IMMCG study reveals clues to how immune system ‘brakes’ prevent self-attack PD-1 and CD73 on naive CD4+ T cells synergistically limit responses to self | Nature Immunology Single-cell transcriptomes and T cell receptors of vaccine-expanded apolipoprotein B-specific T cells Pathogenesis and pathobiology of testicular germ cell tumours: a view from a developmental biological perspective with guidelines for pathological diagnostics Graphical abstract: This study evaluated the interaction between germ... Scientists discover ‘lost world’ of early ancestors in billion-year-old rocks Earliest animals developed later than assumed Figure 4: Model summarizing the regulation and molecular function of... Primordial Life: Scientists Discover “Lost World” of Our Early Ancestors in Billion-Year-Old Rocks Characterizing the mutational burden, DNA methylation landscape, and proteome of germ cell tumor-related somatic-type malignancies to identify the tissue-of-origin, mechanisms of therapy resistance, and druggable targets | British Journal of Cancer Autoimmune Regulator (AIRE) Deficiency Does Not Affect Atherosclerosis and CD4 T Cell Immune Tolerance to Apolipoprotein B Lost world of complex life and the late rise of the eukaryotic crown Updating germ cell tumour pathogenesis – the ability of seminomas for FOXA2-driven extra-embryonic differentiation Titration of 124 antibodies using CITE-Seq on human PBMCs Right ventricular dysfunction and impaired right ventricular–pulmonary arterial coupling in paradoxical low-flow, low-gradient aortic stenosis Genetics re-establish the utility of 2-methylhopanes as cyanobacterial biomarkers before 750 million years ago Putative sponge biomarkers in unicellular Rhizaria question an early rise of animals A ‘lost world’ of early microbes thrived one billion years ago A quantum heat engine driven by atomic collisions ‘Lost world’ of microscopic life in rocks could be humans’ oldest ancestors, experts say Scientists find ‘lost world’ in billion-year-old Australian rock Billion-year-old rocks reveal traces of ancient life Remains of an extinct world of organisms discovered The "First Predators" Ruled a World Full of Bacteria This 'lost world' reveals a new chapter in the evolution of life Molecular Remains of Ancient Complex Life Found in 1.6-Billion-Year-Old Rocks Ancient sponges or just algae? New research overturns chemical evidence for the earliest animals Organisms called Protosterol Biota lived 1.6 billion years ago Figure 3: A) A heatmap including hierarchical clustering and a... The cancer/testis-antigen PRAME supports the pluripotency network and represses somatic and germ cell differentiation programs in seminomas Primary mediastinal germ cell tumours: an immunohistochemical and molecular diagnostic approach New Discovery Reveals the Oldest-known Ancestor of Complex Life Figure 5: A) Summary of found mutations common in each STM entity as... The detection of isochromosome i(12p) in malignant germ cell tumours and tumours with somatic malignant transformation by the use of quantitative real-time polymerase chain reaction Scientists Discover Ancient ‘Lost World’ That Rewrites History of Life on Earth A mixed methods research study on the video‐based counselling method Marte Meo Fig. 2 Global analysis of the histone modification landscape revealed... Re-visiting the Protamine-2 locus: deletion, but not haploinsufficiency, renders male mice infertile Figure 2: GraphPad Prism-based calculation of LD50 doses in GCT cell... Figure 7: Model summarizing the molecular mode of action of romidepsin... Fig. 6: Model summarizing the molecular effects of JQ1 on TGCT cell... Fig. 5: Model of the cellular mechanisms of PRAME. A) Regulation of... Scientists discover ‘lost world’ of early ancestors in billion-year-old rocks