piRNA gene density and SUMOylation organize piRNA transcriptional condensate formation
Topoisomerase 3b facilitates piRNA biogenesis to promote transposon silencing and germ cell development
Somatic piRNA and PIWI-mediated post-transcriptional gene regulation in stem cells and disease
Pachytene piRNAs control discrete meiotic events during spermatogenesis and restrict gene expression in space and time
(PDF) Characterization and comparative profiling of piRNAs in serum biopsies of pediatric Wilms tumor patients
A comparative roadmap of PIWI-interacting RNAs across seven species reveals insights into de novo piRNA-precursor formation in mammals
Malicious jumping genes meet their match: Study reveals cell's adaptive piRNA defenses
Insights into the role of hnRNPK in spermatogenesis via the piRNA pathway
PIWI proteins and piRNAs: key regulators of stem cell biology
Drosophila Piwi distinguishes transposons from mRNAs by piRNA complementarity and abundance
Two-factor authentication underpins the precision of the piRNA pathway
Current Understanding of piRNA in Cardiovascular Diseases
The transcription factor Traffic jam orchestrates the somatic piRNA pathway in Drosophila ovaries
Inherited defects of piRNA biogenesis cause transposon de-repression, impaired spermatogenesis, and human male infertility
Editorial: Functional implications of Piwi proteins and piRNAs in stem cell maintenance and development
Dipteran-specific Daedalus controls Zucchini endonucleolysis in piRNA biogenesis independent of exonucleases
piRNAs are regulators of metabolic reprogramming in stem cells
Embryonic piRNAs target horizontally transferred vertebrate transposons in assassin bugs
Traffic Jam activates the Flamenco piRNA cluster locus and the Piwi pathway to ensure transposon silencing and Drosophila fertility
Powering up piRNAs for heart regeneration
Influence of aging and maternal protein restriction on PIWI-interacting RNA expression in the offspring rat ventral prostate
piRNAs and circRNAs acting as diagnostic biomarkers in clear cell renal cell carcinoma
piRNA-823 Is Involved in Cancer Stem Cell Regulation Through Altering DNA Methylation in Association With Luminal Breast Cancer
Essential functions of RNA helicase Vasa in maintaining germline stem cells and piRNA-guided Stellate silencing in Drosophila spermatogenesis
Researchers identify piRNAs as a highly relevant genetic cause of male infertility
(PDF) piRNA processing within non‐membrane structures is governed by constituent proteins and their functional motifs
Development of a Single-Molecule Biosensor Based on Polymerization-Transcription-Mediated Target Regeneration for Simultaneously One-Pot Detection of Multiple piRNAs
Comparative Analysis of piRNA Profiles Helps to Elucidate Cryoinjury Between Giant Panda and Boar Sperm During Cryopreservation
Mammalian PIWI–piRNA–target complexes reveal features for broad and efficient target silencing
Regulatory mechanisms and biological functions of piRNAs and piRNA/PIWI...
piRNA processing by a trimeric Schlafen-domain nuclease
piRNA loading triggers MIWI translocation from the intermitochondrial cement to chromatoid body during mouse spermatogenesis
The expression of piRNAs and PIWI proteins and the relationship between...
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Chromatin profiling identifies transcriptional readthrough as a conserved mechanism for piRNA biogenesis in mosquitoes
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Binding of guide piRNA triggers methylation of the unstructured N-terminal region of Aub leading to assembly of the piRNA amplification complex
A chromodomain protein mediates heterochromatin-directed piRNA expression
The piRNA pathway is essential for generating functional oocytes in golden hamsters
Morc1 reestablishes H3K9me3 heterochromatin on piRNA-targeted transposons in gonocytes
The two pathways of piRNA biogenesis: primary and secondary (Ping-Pong...
Long first exons and epigenetic marks distinguish conserved pachytene piRNA clusters from other mammalian genes
Unistrand piRNA clusters are an evolutionarily conserved mechanism to suppress endogenous retroviruses across the Drosophila genus
Role of piRNA biogenesis and its neuronal function in the development of neurodegenerative diseases
pre-piRNA trimming and 2′-O-methylation protect piRNAs from 3′ tailing and degradation in C. elegans
PNLDC1 is essential for piRNA 3′ end trimming and transposon silencing during spermatogenesis in mice
Figure. 2. piRNA biogenesis pathways: Ping-pong cycle. Secondary route...
piRNA pathway evolution beyond gonad context: Perspectives from apicomplexa and trypanosomatids
Coupled protein synthesis and ribosome-guided piRNA processing on mRNAs
Biosynthesis of piRNA. (A) Production of piRNA precursors (B) Primary...
Relaxed targeting rules help PIWI proteins silence transposons
RNase κ promotes robust piRNA production by generating 2′,3′-cyclic phosphate-containing precursors
piRNA-guided intron removal from pre-mRNAs regulates density-dependent reproductive strategy
Zucchini consensus motifs determine the mechanism of pre-piRNA production
Mechanisms of piRNA in different CVDs. (A) The combination of CHAPIR...
piRNA-like small RNAs target transposable elements in a Clade IV parasitic nematode
How mammalian piRNAs instruct de novo DNA methylation of transposons
An integrative piRNA analysis of mouse gametes and zygotes reveals new potential origins and gene regulatory roles
AlphaFold structure prediction of the trimeric complex consisting of...
A Pandas complex adapted for piRNA-guided transcriptional silencing and heterochromatin formation
The piRNA targeting rules and the resistance to piRNA silencing in endogenous genes
The evolutionarily conserved piRNA-producing locus pi6 is required for male mouse fertility
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Evolutionarily conserved pachytene piRNA loci are highly divergent among modern humans
Differential expression and correlation of immunoregulation related piRNA in rheumatoid arthritis
AlphaFold predicts a trimeric complex consisting of TOFU-1, TOFU-2 and...
Small-RNA-mediated transgenerational silencing of histone genes impairs fertility in piRNA mutants
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Decoding the 5′ nucleotide bias of PIWI-interacting RNAs
Identification of piRNAs and piRNA clusters in the testes of the Mongolian horse
A satellite repeat-derived piRNA controls embryonic development of Aedes
Pre-piRNA trimming safeguards piRNAs against erroneous targeting by RNA-dependent RNA polymerase
Exonuclease Domain-Containing 1 Enhances MIWI2 piRNA Biogenesis via Its Interaction with TDRD12
piRNA 3′ uridylation facilitates the assembly of MIWI/piRNA complex for efficient target regulation in mouse male germ cells
Gonadal-piRNA pathway vs. proposed model for Protozoa parasites...
Asterix/Gtsf1 links tRNAs and piRNA silencing of retrotransposons
Pathogenic tau-induced piRNA depletion promotes neuronal death through transposable element dysregulation in neurodegenerative tauopathies
Co-dependent Assembly of Drosophila piRNA Precursor Complexes and piRNA Cluster Heterochromatin
Yb Integrates piRNA Intermediates and Processing Factors into Perinuclear Bodies to Enhance piRISC Assembly
The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation
A somatic piRNA pathway in the Drosophila fat body ensures metabolic homeostasis and normal lifespan
Steps of phased piRNA biogenesis: (a) Aub bound to a long piRNA-cluster...
Heterochromatin protein 1a functions for piRNA biogenesis predominantly from pericentric and telomeric regions in Drosophila
MORC3, a novel MIWI2 association partner, as an epigenetic regulator of piRNA dependent transposon silencing in male germ cells
A heterochromatin-dependent transcription machinery drives piRNA expression
Piwi-interacting RNA (piRNA) expression patterns in pearl oyster ( Pinctada fucata ) somatic tissues
Casein kinase II promotes piRNA production through direct phosphorylation of USTC component TOFU-4
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Export of piRNA precursors by EJC triggers assembly of cytoplasmic Yb-body in Drosophila
PIWI-Interacting RNAs (piRNAs): Promising Applications as Emerging Biomarkers for Digestive System Cancer
piRNA regulates transposon silencing. (A) at the transcriptional level,...
Aberrant expression of select piRNA-pathway genes does not reactivate piRNA silencing in cancer cells
Distinct and Collaborative Functions of Yb and Armitage in Transposon-Targeting piRNA Biogenesis
Adaptive Evolution Targets a piRNA Precursor Transcription Network
The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity
New players on the piRNA field
PIWI proteomics identifies Atari and Pasilla as piRNA biogenesis factors in Aedes mosquitoes
piRNA-guided slicing specifies transcripts for Zucchini-dependent, phased piRNA biogenesis
piRNA-1742 promotes renal cell carcinoma malignancy by regulating USP8 stability through binding to hnRNPU and thereby inhibiting MUC12 ubiquitination
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