2023) — Former University of Kentucky Board of Trustee member Zirl A Palmer became Lexington's lone Black pharmacist in the 1950s and emerged as a central figure in Lexington’s African American community until his death in 1982 The following profile on Palmer first appeared in Pharmacy Chronicles: History of Pharmacy SIG Newsletter Big man of the Klan in Lexington was killed there ‘We’re going to kill the biggest Black guy in Lexington,” said Zirl A The interview is part of University Kentucky Libraries’ Louie B The 1968 shootout was a 10-minute gun battle on the streets of Berea anti-Black National States Rights Party that resulted in the death of two carried out a bombing against Zirl Palmer’s Lexington pharmacy in the West End Plaza but Zirl Palmer’s legacy as a community leader and civil rights activist was already firmly established Palmer never set out to become the most prominent Black man in Lexington but as the city’s lone Black pharmacist in the 1950s he emerged as a central figure in Lexington’s African American community until his death in 1982 as the oldest child of James and Lola Allen Palmer Palmer worked as an inspector’s helper for Norfolk & Western Railroad until the age of 21 Army for three years during World War II (1943-46) where he obtained a bachelor's degree in chemistry and mathematics He then spent a year at Howard University in the Graduate School of Chemistry completing courses in the pre-medicine curriculum Palmer finished his training in the College of Pharmacy at Xavier University in Louisiana in 1951 Palmer was an active member of the student body In addition to his work as a reporter for the university paper Palmer was instrumental in establishing a student branch of the American Pharmaceutical Association and served as the student group’s inaugural president Palmer came to Lexington upon graduation in 1951 and opened his pharmacy at the corner of 5th and Race Streets in Lexington’s thriving Black neighborhood of the East End he knew the city had nine Black doctors and four Black dentists His business plan was centered on being the lone Black pharmacist for Lexington’s African American community Palmer’s patience and commitment to professionalism were key many people in the African American community had not seen a Black pharmacist and certainly not one as young as Palmer the community — including some of the local physicians — thought Palmer was too young Without the mentorship of a more senior pharmacist “staying in the books” for the first two years on the job He abided by the wisdom of the Xavier University Dean of Pharmacy who told him “Never dispense anything that you actually don’t know what it is yourself.” So he dedicated himself to study to avoid making any mistakes that would undermine his credibility with the local practitioners or his customers and reliable track record garnered the respect of his community While the absence of a designated pharmacist for the African American community drove business to Palmer his entrepreneurial spirit kept his customers coming back The pharmacy was a gathering place in the neighborhood and was one of the few places in Lexington where the African American community could sit and drink a soda he struggled to find a vendor to sell him ice cream; however Harold Brookings from the Dixie Ice Cream Company won every sales contest in the Lexington area because of his account with Palmer’s pharmacy Palmer sold over 5,000 gallons of ice cream the rest of the ice cream vendors in the city were also interested in doing business with Palmer Palmer understood that it was difficult for his store to compete with the major retail chains when it came to the margins on drugs the profit was to be made on other items in the store Palmer found innovative ways to draw customers into the store beyond the ice cream and soda that had people lined up out the door Palmer saw that there were no calendars depicting Black people so he created his own Palmer’s Pharmacy branded calendars with photographs of the African American community in Lexington causing community members to approach Palmer as early as September to make sure they could secure next year’s calendar When his customers looked at their calendar every day not only did they see images that reflected their community they also saw the name “Palmer’s.” Palmer understood that representation mattered to his community a conviction that was evident in his service to the community separate from his business Palmer also recognized that no businesses in Lexington were processing utility bills like the pharmacies did in New Orleans where he had completed his pharmacy training he began collecting payment for city utilities inside his pharmacy All of these things brought customers into the pharmacy and established Palmer’s reputation as a pillar of the East End community Following the success of his first pharmacy Palmer purchased property in 1959 at the intersection of 5th and Chestnut Street he built a new two-story building to house Palmer’s Pharmacy which opened its doors to the Lexington community in 1961 Palmer again demonstrated his entrepreneurship and commitment to the community by combining essential community services in his pharmacy which housed two physicians and a lawyer in the upstairs suites and Doctor’s Office was the sole Black-owned pharmacy in Lexington at the time and was the first Rexall pharmacy in the United States owned by an African American The success of the East End pharmacy ultimately led Palmer to open a second concurrently operating location in the new West End Plaza Shopping Center on Georgetown Street Palmer’s second pharmacy was adjacent to other businesses and was in a predominantly white neighborhood Palmer recalled that the location made three times the revenue his other pharmacy businesses had taken ten years to make Palmer continued to be a resource in the Black community for matters of health As Black doctors in the community passed away customers would continue to come to Palmer seeking his expertise He advised on matters where he could and made referrals to other doctors when he could not Palmer’s prominence in the community did not go unnoticed 1968 — just days after the racially charged gun battle in Berea that killed two men — a man entered Palmer’s West End pharmacy carrying a brown leather briefcase Palmer and a customer noticed the man and Palmer would later testify that he saw the man leave without the briefcase and the briefcase contained a bomb set on a timer made from a cheap alarm clock Palmer’s pharmacy was in ruins and 10 people were left injured Residents from the nearby Charlotte Court neighborhood rushed to pull survivors from the wreckage Buried in the debris of overturned counters and showcases were Palmer’s wife and daughter who were narrowly saved from the burning building by the heroic men from Charlotte Court Palmer lived in fear for the safety of his family and made the decision not to reopen the pharmacy selling the still-functioning East End store shortly thereafter Palmer continued to serve Lexington as a pharmacist in a local Walgreens and through his service on many state and local councils Palmer made massive contributions to the health and wellness of the African American community of Lexington as a pharmacist but his legacy of service to his community was perhaps even greater Palmer always worked to support and advocate for the Black community as they pursued careers in pharmacy and medicine He and his wife actively encouraged one of his employees to quit her job working the soda fountain to pursue training as a nurse Viola Davis Brown would go on to be the first African American admitted to a nursing school in Lexington the first African American promoted to hospital supervisor at St In addition to creating jobs for clerks and delivery drivers Palmer employed interns from the University of Kentucky College of Pharmacy and wrote recommendations for four of the five Black students he knew had enrolled in Kentucky’s College of Pharmacy as of 1979 In 1972 Palmer was appointed to a seat on the University of Kentucky Board of Trustees by Governor Wendell Ford and reappointed for a four-year term in 1975 by Governor Julian Carroll Palmer was not reappointed in 1979 and protests erupted across the state and from the NAACP Carroll planned to appoint Palmer to the state Council on Higher Education a plan that was never completed after the incumbent decided against resigning his post Palmer was an active participant in the Lexington community He played baseball for the Lexington Hustlers — the local professional Negro League team and the first integrated team in the south — and helped coach the University of Kentucky tennis team He was an active member of Main Street Baptist Church running a health care program in cooperation with the church He was active in local branches of Planned Parenthood and was the first African American member of the Optimist Club and Big Brothers and was a member of the Kentucky Commission on Human Rights at the state and local level Palmer maintained his membership with the American Pharmaceutical Association as well as the National Association of Retail Druggists Palmer’s vast resume of local and state service underscores his commitment to advocacy and his conviction that African American representation mattered at every level In a Lexington Herald-Leader article reflecting on Palmer’s business success and community legacy “It just meant something that a Black person in Lexington could do that He’s always been a mover in the community — many times behind the scenes.” Palmer came to a highly segregated Lexington and made a lasting impact in his communities From benefiting the personal health of the East End customers that he served out of his pharmacies to his advocacy for the rights and representation of the African American community Palmer’s legacy demonstrates the power of the retail druggist to be a community pharmacist in every aspect of the word the University of Kentucky exists to advance the Commonwealth We do that by preparing the next generation of leaders — placing students at the heart of everything we do — and transforming the lives of Kentuckians through education We pride ourselves on being a catalyst for breakthroughs and a force for healing It's all made possible by our people — visionaries disruptors and pioneers — who make up 200 academic programs a $476.5 million research and development enterprise and a world-class medical center Get the best experience and stay connected to your community with our Spectrum News app. Learn More — A new WayPoint center is now open in Lexington at the site of a former historic Black-owned pharmacy The WayPoint initiative under United Way of the Bluegrass is helping underprivileged communities A new center is now open in a historic spot the site of a former historic Black-owned pharmacy was among several state and city leaders in attendance for Monday's grand opening It was supported by a gift from the Marksbury Family Foundation  The historic Palmer pharmacy building in east Lexington was the first Black-owned Rexall pharmacy in the U.S Army veteran Zirl Palmer never reopened it.   But Palmer left behind a legacy as a community leader and civil rights advocate the East 5th Street space will connect people with opportunities to achieve financial stability and independence sat down with the community to gauge its needs for the historic site.  not another redevelopment project that would cause displacement but one that would benefit the folks and the people that live in this neighborhood and call this the East End home,” Brown said “That's why I'm excited today because I think that's how it turned out.”  The WayPoint Center offers services like health screenings financial counseling and help finding a job Mayor Linda Gorton and other leaders gathered for the grand opening “What I see is a strong group of leaders that care about this city," Beshear said they're showing they care about every single part of this city and every single family within Fayette County.”  The WayPoint Center also connects people with providers who can help cover basic needs like emergency food the Palmer Pharmacy in Lexington's East End neighborhood is inching closer to being restored so it can bring community-benefitting services and programs to the area It is one of 40 sites across the country that has received a grant from the National Trust for Historic Preservation's African American Cultural Heritage Action Fund. with the Blue Grass Trust for Historic Preservation After applying two previous times for the grant she said it was thrilling to learn that the third time was a charm and that they had been awarded $50,000 "We immediately just started jumping up and down screaming so yes we were very excited," Sams said Sams said the International Style of the building makes it unique But what makes it truly special is the man who built it: Dr "My reason for coming here [Lexington] was they had roughly nine black physicians and four dentists but no black pharmacists," Zirl said in an audio recording courtesy of the University of Kentucky's Louis B "Segregation really prevailed then and I thought that if I came to an area where they had that many physicians as well as dentists that I couldn't miss as far as making a success in the drug business." The World War II veteran and civil rights pioneer was the first African American to own a Rexall pharmacy in the nation He was also the first African American trustee at the University of Kentucky "He opened up his pharmacy with the spirit of serving the community," Sams said "He had his ice cream and lunch parlor on the bottom floor with the pharmacy shop We just really want to see it serving the community like he wanted it to again." It's working with the Blue Grass Trust to determine how to move forward on the project coupled with the $350,000 already allocated to the project The remaining funds to do a total renovation will likely come from fundraising and the organization or entity that eventually takes ownership of the space To learn more about the history of the building and Dr. Zirl Palmer, including the time his family was attacked by a member of the Ku Klux Klan, read here. You can also watch the brief documentary below: Report a typo (LEX 18) — Today the City of Lexington turned over the keys of the historic Zirl Palmer building to the United Way of the Bluegrass Councilman James Brown represented the first district for seven years when talks of how this building should be transformed began this is one of the projects that I worked on for a few years and to see it come to a successful conclusion is just gratifying in so many ways." this building was home to Lexington’s only Black-owned pharmacy was the third Black pharmacist to practice in the city and was the first African American to own a Rexall franchise in the United States the president and CEO of the United Way of the Bluegrass "I can’t think of a better time to receive the keys to this historic landmark than in the midst of Black History Month." There were several plans for this building that has sat empty for years it will become a Marksbury family WayPoint Center "The WayPoint Center is a collective impact model.. which means helping people row their oars in the same direction The building has meant a lot to the community over decades and now the way this building has aided in helping the community before it will have the opportunity to do so again "Knocking this building down was one of the options on the table and the community spoke out loud and said having a center in place is actually letting the community know they were heard their voices were heard and more than that this is here to help empower them,” says Johnson This center will serve as a resource in the community by aiding in job searches Councilmember Brown says projects like this should create support in communities "So when you work on projects in a neighborhood with the history and with the demographics that the east end has you have to be intentional and you have to be focused on making sure that you don't displace folks and that you're creating a neighborhood resource and opportunities for the folks that live here,” says Brown He says that while this is a big step forward there is still more work to be done in the east end of the city AbleGamers The Worlds Largest Charity for Gamers with Disabilities  It can transition from being a home console to a portable handheld and split itself apart to let friends jump into a game alongside you it does none of these things with any concern for accessibility The system’s options contain zero accessibility features  The closest it comes is the ability to swap between white and black themes so that the handheld does not blind you if you try and play it in the dark which also helps make some of the text more legible  There are some bait-and-switch options that seem promising like “Calibrate Control Sticks” and “Calibrate Motion Controls,” but those only reset the features back to the defaults in case something goes wrong  You cannot rebind buttons or change font sizes the option to increase font sizes would have been most welcome the console itself offers some additional accessibility challenges of its own when using the Switch as a handheld is very responsive and can be used to navigate menus and type in passwords and other info but its usage is almost nonexistent outside of this and if you try and poke the screen while it is propped on its flimsy kickstand it will just scoot the system around or push it over and the one that is attached to the console dock is currently only good for charging the pro controller the console’s biggest accessibility flaw is its default Joy-Cons  When attached to the sides of the controllers they feel fine  They are the same buttons that the 3ds uses but the sticks are more raised (which means they can snag on things if you try and just stuff it in your backpack or bag)  The sticks are fairly flat and very smooth which means that your fingers will slip off them if you hold a direction too long a particular annoyance for games like Mario Kart when you are trying to hold a drift  This problem is exacerbated when the Joy-Con is decoupled from the console  The Switch comes with a makeshift frame that allows you to connect both of the Joy-Cons into one Xbox-like controller Using each Joy-Con as its own controller is a fun feature  Playing Mario Kart or 1-2 Switch with friends before class starts or during a lunch break is a lot of fun but if you try and use the hilariously small controllers in more than short bursts  The amount of inputs (the two shoulder buttons and joystick) versus the size of the controller means that there is no room for you to rest the controller on your palms which means that you have to delicately balance the controller like chopsticks The ability to change the Joy-Cons from one configuration to another was one of the console’s selling points and while the different mash-ups all work to some degree it is not always easy to transition from one to the other  The back of each Joy-Con has a small button that needs to be held down while it is pulled away from whatever dock it is attached to  When they are on the sides of the console which means that I often give up on being delicate and just leave handprints all over the console screen  The smaller attachment that is used to turn each Joy-Con into its own controller is even more of a nightmare as the pieces are smaller and require more force to remove  To exacerbate this problem is the fact that the smaller attachment can pretty easily be slid on upside-down whether it be by a careless Switch owner or just a confused friend (both have happened to me multiple times) you have to grip the attachment and yank it off with a worrying amount of force The Pro Controller solves a lot of the problems that the Joy-Cons have being almost identical to an Xbox controller in both feel and layout but does require that extra purchase on top of a brand new console  The Pro’s buttons are larger and it can even be used as a controller for the PC but it suffers from the same accessibility problems as most other modern controllers namely that there are four shoulder buttons (two on each side though when using a single Joy-Con for a controller there are only two shoulder buttons total) and the lack of any system key rebinds means that this can be problematic for games that also lack that feature Individual games can fix some of these problems The game features some accessibile options such as having the player’s car steer itself with assisted driving The game also allows you turn these options on independently of each other 1-2 Switch core gameplay is involving sound and motion actions that do not require looking at a screen and is very accessible to the blind community Many of the indie games available feature accessible options such as button remapping that the system itself does not include Game developers big and small on the system are leading the way with accessible options that the console itself desperately needs After spending quite a bit of time with the Switch I came to embrace the idea of a home console that could also be taken on the go but was often frustrated with how the features were implemented both in terms of the software and hardware  While many people may just want a home console and couldn’t care less about the mobile aspect that would certainly negate a lot of the accessibility gripes I have but if Nintendo was so focused on that aspect then it should have spent more thought and effort into making it an easy and accessible option  After other companies have come so far in implementing accessibility features built into the console it is disappointing to say the least to see Nintendo ignoring accessibility so completely creating opportunities that enable play in order to combat social isolation and improve the quality of life for people with disabilities We’re using the power of video games to bring people together improving quality of life with recreation and rehabilitation LEXINGTON, Ky. — People gathered for a ceremony to listen to speakers and witness Lexington Mayor Linda Gorton give the keys of the Palmer building to the United Way The organization has a WayPoint Initiative to provide services to people that live in underserved communities The Palmer building will soon be used for that purpose Zirl Palmer owned the building during the 1960's The building is significant because it was the only Black-owned pharmacy in Lexington at the time.  but was also a philanthropist that served his community in several ways including participating in the local branch of the NAACP “I can’t think of a better time to receive the keys to this historic landmark than in the midst of Black History Month," said Timothy Johnson the CEO of the United Way of the Bluegrass "At a time where we celebrate the accomplishments of so many distinguished African Americans we look forward to honoring the legacy of the former owner of this space The Palmer building has been vacant for about 10 years The restoration of this building is expected to be completed later this year and there are plans to have a ribbon-cutting ceremony when the new WayPoint center is ready to open its doors Metrics details a crucial process in hemostasis and thrombosis has garnered substantial attention for its implications in various medical conditions Microscopic examination of blood clots provides vital insights into their composition and structure aiding in the understanding of clot pathophysiology and the development of targeted therapeutic strategies This study explores the use of topological data analysis (TDA) to assess plasma clot characteristics microscopically focusing on the identification of the elements components This approach should enable researchers to objectively classify fibrin networks based on their topologic architecture We tested this mathematical characterization approach on plasma clots formed in static conditions from porcine and human citrated plasma samples where the effect of dilution and direct thrombin inhibition was explored Confocal microscopy images showing fluorescence labeled fibrin networks were analyzed Both treatments resulted in visual differences in plasma clot architecture Significant differences between baseline and diluted samples as well as blood anticoagulated with argatroban TDA could be indicative of clots with compromised stability providing a valuable tool for thrombosis risk assessment offers a promising avenue for comprehensive characterization of clot microstructure This method could contribute to a deeper understanding of clot pathophysiology and thereby refine our ability to assess clot characteristics Gaining a deeper insight into changes of fibrin networks is of substantial interest as a precise characterization and quantification of the clot microstructure may shed light on important functional aspects of hemostasis We here propose topological data analysis (TDA) as a novel mathematical approach to objectively quantify qualitative differences in fibrin networks imaged with confocal microscopy Topological data analysis is an analytical framework to identify the geometric structure within a dataset TDA combines methods from algebraic topology as well as statistical analysis which allows to measure the persistence of certain topological features and eventually to classify the data topologically Images are analyzed by creating geometric structures like vertices edges and surfaces out of pixels depending on their grayscale value This enables to observe quantifiable items such as components and holes in an image the qualitative differences of clot formation should exhibit alterations due to specific changes of the individual components of the coagulation system Decreased concentration of coagulation zymogens by diluting the sample or limiting thrombin functional capacity with an inhibitor could result in a specific pattern of structural changes We propose that this pattern can be evaluated and compared by TDA The data analysis protocol was established using porcine blood samples and its applicability on human blood was investigated subsequently TDA analysis was applied to plasma clots in static conditions All experiments were conducted in accordance with the relevant guidelines and regulations This in-vitro analysis was performed with blood samples from healthy volunteers The study was conducted according to the ethical principles defined by the Declaration of Helsinki the study protocol was approved by the institutional review board of the Medical University of Innsbruck (EK number: 1215/2017 Informed consent was provided by all volunteers prior any study related procedures were undertaken Healthy subjects with an age range between 18 to 85 years were included if none of the following exclusion criteria were met: recent intake of medications that could interfere with the results of the study (such as anticoagulants or anti-platelet medications nonsteroidal anti-inflammatory drugs such as ibuprofen or acetylsalicylic acid pregnant or breast-feeding women as well as presence of hereditary or acquired coagulation disorders Citrated whole blood samples were spiked with different concentrations of argatroban (Argatra® The concentration of the spiked argatroban levels corresponded to drug levels observed in vivo 0.50 µg/mL (spiking step 1; S1) and 1.00 µg/mL (spiking step 2; S2) A baseline sample remained untreated except for the addition of 100 µL PBS (Phosphate buffered saline) to account for a dilution effect by adding the medication After addition of the different doses of argatroban or PBS whole blood samples were incubated for five minutes at room temperature on a roller mixer Blood samples were centrifuged at 2500 g for 15 min to obtain plasma for coagulation analysis and confocal microscopy Results of global coagulation parameters were analyzed with GraphPad Prism version 10.1.0 using repeated measures one-way ANOVA (GraphPad Software, La Jolla, California USA, www.graphpad.com) Clot firmness was analyzed using the viscoelastic testing device ROTEM® gamma (Tem Innovations a point-of-care device to measure whole blood coagulation Coagulation is induced by addition of calcium chloride (STAR-TEM Instrumentation Laboratory Werfen) and tissue factor which triggers the rapid activation of clot formation and polymerization of fibrin via the extrinsic pathway (recombinant tissue factor; EXTEM The clotting time (CT) defines the elapsed time to activation of coagulation; clot formation time (CFT) represents the time between the beginning of clot activation and clot strength of 20 mm Increasing strengthening through polymerization up to maximal clot formation is assessed by the maximal clot firmness (MCF) Normal values for results are 35–80 mm CT 35 to 160 s CFT and 53 to 72 mm MCF The amount of both baseline and diluted samples for measurement was 300 µL and temperature was steady at 37 degrees Celsius Raw images were exported from ROTEM devices and processed with Inkscape (version 1.0 beta1, www.inkscape.org) Coagulation was induced via addition of 5 μL CaCl2 (0.2 mol/L CaCl2 in HEPES buffer Real time live confocal microscopy was performed with a spinning disk confocal system (UltraVIEW VoX; Perkin Elmer USA) connected to a Zeiss Axio Observer Z1 microscope (Zeiss Images and Z-stacks with a height of 10 µm were acquired using Volocity software (Perkin Elmer) using a 63 × oil immersion objective with a numerical aperture of 1.42 The (A) original (left), processed (center) and segmented (right) image of a human fibrin network after spiking with 0.5 µg/mL of argatroban (see also Fig. 3) (B) Persistence diagram to illustrate the mathematical processing using the segmented image blue points represent components and orange points holes Due to the high resolution of the given data a vast share of the computed features is due to noise is computed in order to distinguish between distinct features and noise we provide the number of components and holes for each segmented image Points below the thresholds are plotted smaller and more transparent than points with high persistence. Note that introducing such a threshold reduces the number of topological features drastically (Fig. 1B) The definition of Wasserstein distance is as follows: let p ≥ 1 then pth Wasserstein distance of two persistence diagrams d1 and d2 is defined as where σ ranges over all bijections from d1 to d2 and ||·||∞ denotes the infinity norm Since we added the diagonal to a persistence diagram the set of all bijections from d1 to d2 is non-empty For n ∈ N define a persistence diagram dn = {(0 But since the number of points above the diagonal goes to infinity as n → ∞ the limit is not a persistence diagram anymore One therefore adapts the definition of persistence diagrams where N( ∈) denotes the number of boxes of size ∈ needed to cover the non-zero pixels in the binarized images we assess the mean difference from baseline with respect to the Wasserstein distance from the diagonal by applying a paired t-test we provide mean Wasserstein distances with corresponding 95% CIs we assess differences in fractal dimension number of components and holes as well as several laboratory parameters To assess and verify the effect of the interventions addition of the thrombin inhibitor argatroban and dilution of porcine plasma samples global parameters of coagulation as well as viscoelastic tests were performed Median baseline aPTT was 32 s (IQR 30–32) which increased for approximately 25 s after addition of 0.5 µg/mL (S1 IQR 56–61) and 1.0 µg/mL argatroban (S2 The determination of fibrinogen levels was similarly affected returning decreased concentrations after each spiking step The median baseline level of fibrinogen was 258 mg/dL (IQR 245–270) 230 mg/dL (IQR 224–237) after S1 and 185 mg/dL (IQR 184–192) after S2 (p = 0.0453) Viscoelastic measurements of (A) human plasma (blue) spiked with 0.5 µg/mL (yellow) or 1.0 µg/mL argatroban (red) and (B) porcine plasma (blue) diluted with a gelatin-based colloid (pink) MCF mean clot firmness; Results of pooled samples (n = 3) Porcine (pooled plasma) fibrin network without dilution (Baseline left) and after 30% dilution with gelatine (centre) or hydroxyethyl starch (HES Corresponding persistence diagrams are presented in the second row The fewer components due to dilution with HES were also reflected in viscoelastic tests since the reduction of maximum clot firmness (MCF) compared to baseline measurement (both p < 0.05) was higher with HES (BL 25 ± 2 vs 4 ± 3 mm after dilution) than with the gelatin-based colloid (BL 27 ± 7 vs For components, the Wasserstein distance from the empty diagram, i.e. the diagonal, verifies these observations that the baseline is comparable to gelatin, but not to HES (see Table 1) This is reflected by the long distance of components between baseline and HES The differences in the Wasserstein distance for holes from the diagonal is less blatant nonetheless the distance between baseline and HES is again higher than the distance between baseline and gelatin-based colloid no distinction between baseline and gelatin and a marginal difference between baseline and HES is observed Explicitly counting the number of components again shows similar results between baseline and gelatin-based colloid while the network after dilution with HES has less than half the number of components left) compared to networks imaged after addition of 0.5 µg/mL (spiking step 1) and 1.0 µg/mL argatroban (spiking step 2) where components are represented by blue squares holes by red diamonds and the lines represent the associated silhouettes The observed differences between the networks were verified by the measures presented in Table 2 The Wasserstein distances reveal significant differences in the components for both spiking steps and a significant difference from baseline to the second spiking step in the holes The mean Wasserstein distance from the baseline persistence diagram compared to spiking step one (S1) and spiking step two (S2) is 59.44 (41.61 to 77.26) and 71.24 (47.73 to 94.75) for components and 9.69 (7.36 to 12.02) and 9.5 (7.49 to 11.51) for holes This is in accordance with the pairwise differences The fractal dimensions show only small differences among the natural network as well as in the second spiking step (S2) While a significant difference between baseline and S1 is observed no significant alterations are detected between baseline and S2 Counting components of the binarized images shows a decrease in the number of components after spiking Counting the number of holes captures significant differences between baseline and S1 and baseline and S2 Due to the more rigid structure after the first spiking step while the second spiking step reduces the number of fiber cross points of the network and hence decreases the number of holes again This study shows for the first time that the mathematical method of topological data analysis is suitable to assess differences in the architecture of fibrin networks due to pharmacological treatments The structural changes after dilution of pooled porcine plasma as well as the topological variations induced by argatroban are captured in the persistence diagrams We could show the feasibility of this mathematical approach to capture differences of the functionality of the coagulation system within a species by extracting information from multidimensional greyscale images By adding a method to evaluate morphological characteristics of the end product of the coagulation process we expect that this approach might provide a new avenue to explore pathophysiological subtypes in patients with coagulation dysfunctions The TDA method might complement already available tools to investigate the functional properties of the coagulation system and could be a helpful tool to evaluate the influence of various drugs on coagulation or to characterize the response to a certain treatment TDA is a mathematical approach useful for quantification of morphological differences of fibrin clots It remains to be investigated in further studies how this new method may be integrated into scientific and clinical routine and how evaluation of fibrin network density could become an additional tool for identifying patients at risk for bleeding or thrombosis or treatment response in various diseases Relevant data will be freely available to any researcher wishing to use them for non-commercial purposes without breaching participant confidentiality The datasets generated during and/or analysed during the current study are available from the corresponding author on reasonable request Lim, H. 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A new structural biomarker that quantifies and predicts changes in clot strength and quality in a model of progressive haemodilution. Thromb. Res. 134, 488–494. https://doi.org/10.1016/j.thromres.2014.05.039 (2014) Chazal, F. F., Brittany, T., Lecci, F., Rinaldo, A. & Wasserman, L. Stochastic convergence of persistence landscapes and silhouettes. ArXiv https://doi.org/10.48550/arXiv.1312.0308 (2013) An Application of Topological Data Analysis to Fibrin Networks (University of Innsbruck Determination of the topology of factor XIIIa-induced fibrin gamma-chain cross-links by electron microscopy of ligated fragments Weisel, J. W. & Litvinov, R. I. Fibrin formation, structure and properties. Subcell. Biochem. 82, 405–456. https://doi.org/10.1007/978-3-319-49674-0_13 (2017) Chen, J. & Diamond, S. L. Reduced model to predict thrombin and fibrin during thrombosis on collagen/tissue factor under venous flow: Roles of gamma’-fibrin and factor XIa. PLoS Comput. 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Haemostasis 26, 258–265. https://doi.org/10.1159/000217216 (1996) Download references Department of Anaesthesia and Intensive Care Medicine Department of Anaesthesiology and Intensive Care Medicine Sanatorium Kettenbruecke der Barmherzigen Schwestern GmbH M Berger established the image processing and the mathematical data analysis by TDA and analysed all image material and has written the manuscript T Hell conceptualized the project and supervised TDA development as well as application and proof read the manuscript A Tobiasch performed viscoelastic measurements J Martini planned porcine experiments and contributed to writing the manuscript A Lindner has contributed to porcine experiments H Tauber has contributed to porcine experiments M Bachler performed anticoagulation experiments and contributed writing the manuscript. M Hermann performed confocal live imaging of plasma clots conceptualized the project and proofread the manuscript The authors declare no competing interests Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Download citation DOI: https://doi.org/10.1038/s41598-024-63935-7 Anyone you share the following link with will be able to read this content: a shareable link is not currently available for this article Sign up for the Nature Briefing newsletter — what matters in science "Culture stands on the front-line of conflict – it should be at the front-line of peace building.” - UNESCO Director General Irina Bokova the result of a dispute between groups of society formed over a common culture cultural and religious monuments were specifically targeted as visual symbols belonging to the other group Hundreds of mosques and other Islamic religious sites historic bazars and a large number of kullas as well as Serbian Orthodox religious monuments were damaged or destroyed during and after the conflict When inter-ethnic violence briefly but intensely resurged in March 2004 Serbian Orthodox churches and monasteries in different areas became the target of attacks by rioting groups of Albanians While traditional conflict-resolution methods are primarily tailored to address differences of interest between states identity-based conflicts require a new approach cultural heritage protection had to become an intrinsic element of the peace-building process In the immediate aftermath of the conflict the international community focused on the physical protection of religious and cultural sites the NATO peacekeeping forces secured the most prominent Serbian Orthodox monasteries the United Nations Mission in Kosovo (UNMIK) named the preservation of cultural heritage as one of the benchmarks to be achieved by the provisional institutions of self-government in Kosovo Alarmed by the resurgence of ethnic violence in 2004 the international community the following year pledged US$10 million for the protection of cultural and religious heritage sites at a donor conference organized by UNESCO together with the Council of Europe and the European Commission Safeguards for the protection of religious and cultural heritage were included among the guiding principles of the Kosovo status process initiated by the UN Security Council in 2005 The 2007 Comprehensive Proposal for the Kosovo Status Settlement contained an annex with protection mechanisms Although the adoption of the proposal as a peace treaty failed after Kosovo institutions unilaterally declared independence in 2008 The most important were the establishment of special protective zones around more than 40 Serbian Orthodox sites and the establishment of an Implementation and Monitoring Council a high-level dialogue platform bringing together the Serbian Orthodox leadership with the Kosovo government to discuss issues affecting these zones The OSCE and the Council of Europe supported the Kosovo institutions in developing the necessary legal and institutional framework for heritage protection a European Union representative co-chairs the Implementation and Monitoring Council meetings while the OSCE provides technical expertise Installing legal and institutional mechanisms to protect the rights of former opponents to the symbols of their cultural identity was but a first step towards reconciliation in Kosovo even this first step required an immense effort on the part of community leaders and international peace builders Effective implementation was protracted over years hampered by a lack of political support and inadequate financial and human resources A buy-in by the Serbian Orthodox Church into the process required extensive international advocacy Cultural heritage protection was not a fast-selling item the mechanisms the international community introduced were able to trigger a number of positive developments these have gone beyond the mere protection of physical sites to initiate a process of dialogue and reconciliation After the Implementation and Monitoring Council began to meet on a regular basis in early 2013 members of the Serbian Orthodox Church also increasingly participated in local level meetings together with central and local government representatives.  Leaders of all religious beliefs in Kosovo entered into an OSCE-sponsored inter-ethnic dialogue process to jointly advocate for the protection of religious freedom Municipalities are assuming more and more responsibility for ensuring that the law applicable within protective zones is respected Kosovo Albanian mayors and local governments interact with the Serbian Orthodox communities in their municipalities The fact that Kosovo Albanian officials – mayors ministers and even the president – are increasingly visiting Serbian Orthodox sites and participating in the Serbian Orthodox Church’s religious festivities is a major milestone in the development of a constructive relationship between the communities the Kosovo Police established a special unit trained to secure the most vulnerable sites and have taken over almost all security responsibilities from the international community Vandalism and desecration of Serbian Orthodox churches cemeteries and monasteries have a substantial impact on the Kosovo Serb community’s perception of security This violence is committed by a small portion of the Kosovo Albanian community but a larger number will ascertain that their community never received an apology or reparations for the destruction of Albanian sites in Kosovo during the conflict the Kosovo Serb community will not see a sustainable future for itself if it cannot live and express its cultural identity without fear Incidents like the desecration of Orthodox cemeteries in retaliation for the demolition of an Albanian monument in southern Serbia threatening graffiti sprayed on walls and doors of Serbian Orthodox monasteries or stones thrown at Serbian Orthodox pilgrims visiting religious sites clearly demonstrate how fragile any rapprochement between the communities is and how quickly cultural heritage can again become the target of hate crimes Landowners who struggle with the difficult economic situation often lack understanding for the restrictions to their property rights within special protective zones Even after more than fifteen years of international engagement more needs to be done to ensure sustainable cultural heritage protection and to consolidate effective safeguards for cultural identities in Kosovo The challenge remains to transform what was seen as symbols of different identities into the bricks for building bridges between divided communities established in 1999 as “Pillar III” of UNMIK and primarily mandated to establish democratic institutions rule of law agencies and human rights protection mechanisms after the conflict today increasingly includes religious and cultural heritage protection initiatives in its programmes  “Because religion is such an important part of ethnic identity even though the conflict in Kosovo wasn’t religious but ethnic in nature a lot of these religious heritage sites were destroyed or damaged in the conflict and its aftermath rebuilding them and protecting them is a significant element in achieving reconciliation and a lasting peace,” says Head of Mission Ambassador Jean-Claude Schlumberger With a team of resident experts at its headquarters in Prishtinë/Priština and in its field offices across Kosovo the OSCE Mission monitors developments around cultural heritage sites and supports the work of the Implementation and Monitoring Council It engages in mediation efforts between religious and political community leaders supporting dialogue and offering a neutral problem-solving platform at both central and local levels The Mission particularly encourages women to participate in inter-religious dialogue and religious and cultural heritage protection Not only does this provide valuable employment opportunities it is also necessary for effective peace building Women who lost loved ones during the conflict or became victims of violence themselves are an essential part of any peace process The Mission also pays attention to the important role young people can play in building confidence and tolerance among multicultural communities Through art competitions like the 2015 photography contest it brings together students of different communities to promote a sense of shared heritage and dismantle common stereotypes regarding “the others” It thereby complements educational projects of the Council of Europe the European Union and local NGOs such as Cultural Heritage without Borders Students participating in visits to cultural and religious heritage sites are often exposed to the culture of other ethnic groups in their immediate neighbourhood for the first time Children of all communities visiting cultural and religious heritage sites across Kosovo – and their parents supporting such initiatives – are encouraging signals that walls are starting to crumble The Kosovo experience shows that cultural heritage protection is a necessary element of the peace-building process after an identity-based conflict not only because cultural symbols were a target during conflict Proactively using cultural heritage protection to bridge ethnic and religious differences is a necessary precondition for sustainable peace in a society whose members attribute crucial importance to elements of their cultural identity Protection mechanisms that give equal importance to the cultural and religious heritage of all communities are likely to find the broadest public support and thus be the most effective If the rules of special protective zones in Kosovo were also applied to more than a handful of non-Orthodox sites land owners would find it much harder to blame a specific community for unfair treatment and impediments to their socio-economic development Cultural heritage management should go beyond mere preservation It has value for local economic development but also in the creation of employment opportunities in the restoration management and promotion of heritage sites If members of all communities are involved in and directly benefit from this process they are likely to gradually appreciate the value of cultural heritage regardless of its religious or ethnic affiliation Smart cultural heritage management also specifically targets young people as future caretakers cultural heritage may even contribute to the development of a joint Kosovo identity that leaves religious or ethnic affiliation aside the international community has a certain responsibility and soft power For a positive impact among members of the public it will be crucial that the international community recognizes the equal and universal value of the heritage of the different communities in Kosovo for example through the inclusion of sites representing the cultural heritage of all communities on the UNESCO World Heritage list Such international recognition could well contribute to the communities taking pride in Kosovo’s cultural heritage and eventually losing sight of to whom it belongs Päivi Nikander is Deputy Head of the OSCE Mission in Kosovo Valerie Zirl served as political adviser to the Head of the OSCE Mission in Kosovo for more than five years.  Security Community is the OSCE’s online space for expert analysis and personal perspectives on security issues The views expressed in the articles are those of the authors and do not necessarily reflect the official position of the OSCE and its participating States Let us use our new magazine as a vehicle for an open exchange of views and constructive dialogue to encourage convergence among participating States and their societies and thus clear the way for building a true security community fresco in the vault of the Parish Church in Zirl who on this day through your only begotten Son have 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Joseph Prior, pastor of St. John the Evangelist Parish, Morrisville Easter hymn with lyrics: “Jesus Christ is Risen Today” CatholicPhilly.com works to strengthen the connections between people families and communities every day by delivering the news people need to know about the Catholic Church you and hundreds of other people become part of our mission to inform form in the Catholic faith and inspire the thousands of readers who visit every month Please join in the church's vital mission of communications by offering a gift in whatever amount that you can ― a single gift of $40 Your gift will strengthen the fabric of our entire Catholic community and sustain CatholicPhilly.com as your trusted news source USCCB: Statement of USCCB on Vatican’s Document Addressing Pastoral Blessings Pope Francis’ May 2023 Prayer Intention | Watch Video Catholic Charities of Philadelphia Returns to Roots Honest Conversations Reflect on Vision for the Future of Philadelphia’s Church Dan Tarrant Brings God to the World Through Catholic Filmmaking Birders from all over Montana hurried to Missoula in December to get a glimpse of this rare species The most distinguishing field marks on a fieldfare are the gray head and rump This slightly out-of-focus flight picture shows the fieldfare’s wing linings that was seen in the Missoula area in late April and May of that year The species is common in Asia and often seen in the Western Aleutians and Pribilof Islands in the Bering Ocean It was first identified on the Christmas Bird Count on Dec It was found west of Missoula near Council Grove State Park on Harbor’s Bridge Road and La Viola at a private residence feeding in a row of crab apple trees with waxwings and robins Birders from all over Montana hurried to Missoula to get a glimpse of this rare species I heard about it a day after it was found and was unable to get there until the next day You can often miss a rarity by being three days late there were about 10 birders standing in the road with scopes and binoculars focused on a tree I got the bird within five minutes of arriving on site number 373 for Montana and 605 for North America Additional birders came and went the remainder of the morning The species continued to be in the area through Dec It is impossible to say if the bird moved on or a raptor such as a sharp-shinned hawk preyed on it many more would have made the trip to Missoula the Montana birding Internet sites are buzzing with the latest updates on fieldfare sightings I received an email from a Minnesota birder that I met in the Pribilof Islands (off the coast of Alaska) in September “I am on my way now — driving — and hope to be in Missoula late tonight I hope the bird sticks.” He saw the bird on Dec the last record of this bird in the United States was in 1991 in Northern Minnesota The closest sighting to Montana for the species was Vancouver There are additional sightings of the species in Eastern Canada and Nova Scotia over the years If you look at the sightings for this species on eBird it has been recorded in all of Western Europe from Spain north to Sweden and from the British Islands east to Ukraine There are a few scattered sightings in Russia all the way to the Bering Sea there are no sightings in the Aleutian Island chain or mainland Alaskan on eBird Several ornithologists have noted that there are a few sightings from Alaska that were not recorded on eBird the two Western United States continental sightings on eBird are Vancouver and now Missoula It is assumed that these Eastern Canadian birds made it across the Atlantic Ocean from Western Europe why was it not sighted en route to Montana It seems unlikely that it came from a sparse population in Asia Some have suggested that records for Asia are incomplete and it may breed in Asia more than eBird records indicate “Are there known differences between Asian and Western European populations?” One ornithologist responded: “Fieldfares from the eastern end of the range are supposed to average slightly paler and longer-winged and they’ve been proposed as a separate race but I don’t think that subspecies is recognized by most authorities.” Thus the answer to the origin of this fieldfare will remain open for discussion The most distinguishing field marks are the gray head and rump The breast spots are arrowhead in shape on a buffy breast and extend along the sides as well as the breast In flight the wing linings are white and flash in flight The slightly out-of-focus flight pictures show the wing linings These pictures were taken by a birding friend What started off as a normal Missoula Christmas Bird Count put the Montana and national birding community in a state of excitement this year get out there and bird often; you never know what you might see The potential is always there for a rarity such as this one that rewrites the list of birds species found in Montana don’t ignore it; get ahold of other birders and identify the species A Christmas bird count is planned Friday, Jan. 1, 2016, with birders meeting at 8 a.m. at the parking lot of Uncle Buck’s at the Warm Springs exit off Interstate 90. The counts consist of a 15-mile count circle divided into sections with a team of at least two bird counters searching each area. Less experienced bird watchers are paired with experienced birders, providing a great way for beginners to learn the skills of field identification. The task of each team is to identify, count and record every individual bird by species within their section of the circle. This information is later tabulated for the entire count circle and reported via Audubon’s website, www.audubon.org.bird.cbc. Pre-registration is not necessary, but it is helpful for count leaders to know how many volunteers will be participating. Contact Gary Swant at birdmontana1@hughes.net for Grant-Kohrs and Warm Springs and Jack Kirkley at j_kirkley@umwestern.edu for the Clark Canyon CBC count. Area counts are organized by the Pintler Audubon Society. Here are The Montana Standard's top stories for the week of Dec. 26, 2015 through Jan. 1, 2016. But people urged to be responsible and not harass feathered friends Fall is always a great time to look for rare and unusual bird species that might come to your yard. This fall was no exception for me with two… One of the more challenging aspects in birding is identifying a species in juvenile, spring and fall plumages. Some birds don’t vary much in p… Owls by their very nature of being nocturnal are hard to find and see. During the breeding season, they can be heard calling, but that is most… The greatest cause of bird depredation is lack of habitat. As wetlands are drained, grass meadows converted to subdivisions, and old-growth fo… As I mentioned in my last article on bird mortality, habitat destruction and loss is the single biggest factor on declining bird populations w… The gyrfalcon is one of the most sought-after birds of prey in Montana as it is rather rare and only a winter visitor to the Upper Clark Fork … One of the frustrating things for the casual birder is name changes — one species being split into two, or two species now only one. Often the… One of the birds I get a lot of comments on is the American White Pelican. I suppose it’s because everyone knows what pelicans looks like, and… Birders of all skill levels are encouraged to participate I grew up hunting grouse with my dad in the Upper Clark Fork River Valley. In those days, we hunted fool hens and blue grouse. I rarely hear t… Continuing in our series of articles on birding, I want to share with you the most exciting and relevant new development in birding: eBird. One of the more common questions I get from folks is where should I go birding in southwest Montana? Most folks are familiar with the Common Loon as they are a symbol of the wilderness and the great outdoors. Many a poster has been designed of… All owls can be a challenge to find with the exception of the great horned owl, which commonly lives among humans and has a familiar call. I have been asked on occasion how I choose which bird to write about month to month. I do make an effort to write articles that are seasonal i… Check out EventsinButte.com for more activities or to list your event. Fall can be a wonderful time to see rarities that pass through our area. Last month I wrote about the Anna’s hummingbird that spent several da… There are eight species of swallows in North America with seven species in Montana. The cave swallow is mostly found in Texas and Mexico. Tree… I have been fortunate in my life to have the time and financial resources to bird in 15 countries around the world, and this coming November m… Montana is a reasonably good place to bird with 433 species found within our borders. There are no endemics (found only in Montana) species, b… There are only three species of waxwings in the family Bombycillidae in the world with two species in Montana and North America. The two North… As fall and winter approach, I have been thinking about birds that overwinter in the Upper Clark Fork Valley. The American dipper is an often … Birders from all over Montana hurried to Missoula in December to get a glimpse of this rare species, the fieldfare. It’s a member of the thrush family. The most distinguishing field marks on a fieldfare are the gray head and rump. The back is purplish brown, and the tail is blackish. The fieldfare is a large thrush, the same size as the American robin, another thrush, at 10 inches. This slightly out-of-focus flight picture shows the fieldfare’s wing linings. Get up-to-the-minute news sent straight to your device. Account processing issue - the email address may already exist Your account has been registered, and you are now logged in. Invalid password or account does not exist Submitting this form below will send a message to your email with a link to change your password. An email message containing instructions on how to reset your password has been sent to the email address listed on your account. Austria is famed for being an all around pro at all things seasonal and the markets in this city never fail to raise Christmas cheer One of the best and most traditional takes place in front of the iconic “Golden Roof”—a building gifted by the Emporer to his wife in Austria’s Imperial days—and sees clusters of wooden stalls selling a variety of handcrafted treats and trinkets and serving a variety of homemade dishes Christmas Market Innsbruck | © Austrian Tourist Board Best of Both Worlds It’s hard to choose between city breaks and country getaways and Innsbruck offers its visitors both The city has a modest yet interesting cultural scene you can be submerged in meadows and forests The area surrounding the city contains many gorgeous little villages that can be easily reached for day-trips—try Rum Designed by architect Zaha Hadid, the Nordkette cable car lifts you high into the sky and into the wilderness giving unobscured panoramic views of awe-inspiring Alpine landscapes that hug the city the journey takes you across unique views of the city below and then transforms over time to become idyllic countryside Peace and Quiet Although the capital city of Vienna is a must-visit destination when exploring Austria around the peak months it becomes rammed with tourists Innsbruck is the perfect place to visit if you want peace and tranquility Sign up to our newsletter to save up to $800 on our unique trips See privacy policy leading you through thick forests and lush meadows Adlerweg – Innsbruck | © Österreich Werbung / Nina Baumgartne See & Do Lesser-Known Summer Destinations to Visit in Europe See & Do The Best European Cities to Visit in July Guides & Tips The Best European Cities to Visit in December See & Do The Best European Cities to Visit in Autumn See & Do The Best European Cities to Visit in October Architecture An Art Nouveau Architecture Tour Of Vienna See & Do The Best European Cities to Visit in Summer Guides & Tips The Best European Cities to Visit in November See & Do The Best Road Trips in Austria Guides & Tips Beat the Crowds with these Alternative Summer Destinations Guides & Tips This Is Europe's Ultimate Road Trip See & Do The Best European Cities to Visit in September US: +1 (678) 967 4965 | UK: +44 (0)1630 35000 tripssupport@theculturetrip.com © Copyright 2025 The Culture Trip Ltd This website is using a security service to protect itself from online attacks The action you just performed triggered the security solution There are several actions that could trigger this block including submitting a certain word or phrase You can email the site owner to let them know you were blocked Please include what you were doing when this page came up and the Cloudflare Ray ID found at the bottom of this page You can read this article in 3 minutesAgnieszka Kulikowska - Wielgus Photo: Wikimedia / Jochen Teufel CCA SA 3.0 The night-time ban on heavy goods vehicles on the A12 motorway in Tirol allows for some exceptions they are to expire at the end of this year Night traffic is banned on the A12 in Brenner in both directions between 6 km (near Langkampfen) and 90 km (Zirl) The ban covers trucks and articulated vehicles with a maximum gross vehicle weight of more than 7.5 t as well as trucks and self-propelled machinery with trailers where the gross vehicle weight exceeds 7.5 t these vehicles cannot use the route during the following hours: Exempted from the ban are heavy duty vehicles meeting the Euro 6 emission standard (provided that the Euroclass is confirmed by the vehicle’s appropriate marking in accordance with the IG-L regulation on the marking of emission classes). However this exception expires on 31 December 2020 only the following will be exempted from night-time traffic restrictions: – transports carrying predominantly perishable food with a shelf life of only a few days or periodic printed materials (newspapers and magazines) – transport necessary for the provision of emergency medical care – transport related to the construction and reconstruction of road infrastructure on the A12 and A13 motorways the development of railway infrastructure on the Munich-Verona route or the construction of the Brennerbasistunnel railway tunnel – transport subject to loading or transhipment to rail transport to or from the railway terminals in Hall and Wörgl provided that such suitable transport documentation is available on the same section of the Tirol motorway (A12 between Langkampfen and Zirl in both directions) there are traffic bans on heavy goods vehicles over 7.5 t in the lowest emission classes Journeys as part of combined transport for the purpose of rail loading (provided that suitable documentation is available) are nonetheless exempt in the following cases: – to the Hall railway terminal (access possible only in the eastern direction – to the Wörgl railway terminal (access possible only in the western direction Pölös Zsófia Journalist Trans.info | 5.05.2025 Agnieszka Kulikowska - Wielgus Journalist Trans.info | 5.05.2025 Sabina Koll Journalist Trans.info | 5.05.2025 GXO to manage Northern Italy transport operations for PRG retail groupPölös Zsófia Journalist Trans.info | 5.05.2025 Verpasse nicht die neuesten Inhalte von diesem Profil: Melde dich an um neue Inhalte von Profilen und Bezirken zu deinen persönlichen Favoriten hinzufügen zu können Willi Köstinger (74) aus Seefeld am 7.1.2014 verstorben darunter auch Olympiateilnehmer und -Sieger im Nordischen Sport begleiteten den im Gasteinertal aufgewachsenen "Loipen-Papst" und Bergfreund Willi Köstinger (74) am 14.1.2014 auf dem letzten Weg Der Teilnehmer bei Olympia 1964 in Innsbruck-Seefeld hätte im Mai dieses Jahres mit Gattin Christa in seiner Heimat Seefeld Goldene Hochzeit gefeiert und Weihnachten erlebte er noch mit allen Kindern und Enkerln um diesen Inhalt mit «Gefällt mir» zu markieren Es können nur einzelne Videos der jeweiligen Plattformen eingebunden werden Es können nur einzelne Beiträge der jeweiligen Plattformen eingebunden werden um selbst mit eigenen Inhalten beizutragen.