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The fate of the CVE Program—a database that catalogs publicly disclosed security vulnerabilities—was unknown over the past 24 hours
Yesterday, it was leaked that the maintainer of the CVE Program, MITRE, sent a letter to CVE board members
saying that funding for the CVE program was set to expire today
including deterioration of national vulnerability databases and advisories
and all manner of critical infrastructure,” the letter said
Most of the funding comes from the U.S. Cybersecurity and Infrastructure Security Agent (CISA), which at the time the letter was published has not renewed the contract. Fortunately, this morning, CISA did renew its contract with MITRE
ensuring the continuation of the CVE program
Ariadne Conill, co-founder and distinguished engineer at Edera
commented that the loss of the program would be catastrophic
“Every vulnerability management strategy around the world today is heavily dependent and structured around the CVE system and its identifiers,” she said
a new foundation has been formed to further ensure the “long-term viability
The CVE Foundation was founded by active CVE board members
who have been working on this for the past year because they were concerned about the program being reliant on a single government sponsor
as a cornerstone of the global cybersecurity ecosystem
is too important to be vulnerable itself,” said Kent Landfield
“Cybersecurity professionals around the globe rely on CVE identifiers and data as part of their daily work—from security tools and advisories to threat intelligence and response
defenders are at a massive disadvantage against global cyber threats.”
The CVE Foundation plans to release more information over the next several days about its structure
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As announced by the organization Monday afternoon
native has officially signed with Birmingham Legion FC of the United Soccer League
Dourado joins the ranks of professional soccer on the heels of a standout five-year tenure with the Knights
during which he totaled 43 goals and six assists on the strength of 191 shot attempts and 90 shots on goal
He also registered 15 game-winning goals and converted four of his six career penalty kick tries
Upon the conclusion of his collegiate career
his 43 goals ranked fifth most on the UCF all-time list
He also departs UCF in sixth place on the all-time career points list
Dourado in 2024 earned Sun Belt All-Conference First Team honors, representing his fourth consecutive campaign tabbed to a conference’s post-season First Team. His six goals not only paced the team, but also ranked eighth most in the Sun Belt overall, and his 12 points finished second on the squad to Clarence Awoudor’s 13
The forward gained most of his offensive traction down the stretch when his team needed it the most this season
scoring four goals in the team’s last two matches
including his first career hat trick against South Carolina Nov
1 and an 89th-minute game-winner against Coastal Carolina Nov
His hat trick in the team’s home final marked the first by a Knight since Alessandro Campoy’s showing against FGCU Sept
and also lifted him beyond the 40 career goals scored plateau
The effort clinched Sun Belt Offensive Player of the Week recognition for Dourado as well
Follow UCF men’s soccer on X (@UCF_MSoccer)
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From generation to generation
the Guarani Kaiowá way of life endures in the Dourados Reserve (MS)
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On a Saturday morning, about 20 children gather with Dona Floriza, a Guarani Kaiowá healer, in a classroom in the Jaguapiru village, in Dourados Indigenous Reserve (RI)
is passed down from one generation to the next
because today’s children speak more Karai Reko (a non-indigenous way)
their grandfathers may no longer speak Guarani and have lost the language
after explaining to the students how seeds gave rise to food
there was only a little bit of lighting.
– Let’s plant it because this seed will generate for the entire country.”
The project developed by Floriza Souza and her husband
was one of the ways found by the couple to perpetuate traditional Guarani Kaiowá knowledge and practices
even in the adverse context of a Reserve created to confine indigenous people and free up their lands for colonization
From the elderly to the youth, the forms of resistance found by the Guarani Kaiowá indigenous people are multiple, even in the midst of escalation of violence and attacks on their territories
From the Dourados Reserve came names such as rappers Brô Mc's and Jovens Conscientes
filmmakers Graciela Guarani and Michele Concianza
as well as academics such as Indianara Ramires Guarani Kaiowá and Izaque João
The number is equivalent to more than 10% of all indigenous people in the state of Mato Grosso do Sul
the area reserved for them has a population density more than three times greater than that of the state capital in which it is located
Data from the Special Indigenous Health District of Mato Grosso do Sul (DSEI-MS) indicate that the population of the Reserve is even larger than that recorded in the 2022 Census
with at least 16 thousand indigenous people living within the Reserve and its surroundings
as explained by anthropologist Diógenes Cariaga in an article published in the book Povos Indígenas no Brasil 2011-2016 about the one hundred years of the Reserve
many families have begun to reclaim areas adjacent to the reserves
as a way of accelerating the publication of reports identifying traditionally occupied lands
explains the professor at the State University of Mato Grosso do Sul (UEMS) and member of the Socio-Environmental Support and Incentive Network (RAIS)
Although the IBGE has not yet released specific data regarding the indigenous presence in the areas surrounding the Reserve
the movement of indigenous people to these reoccupied villages is already beginning to appear in the 2022 Census figures
as pointed out by indigenous demographer Rosa Colman
from the Federal University of Grande Dourados (UFGD) and also from RAIS
we can observe a small increase in the indigenous population of the reserve
but we know that many people from the reserve moved to the various camps that were formed and expanded around the Dourados reserve,” she states
more than half are between the ages of 0 and 29
the majority of young people are male (53%)
“You can see that the [age] pyramid is more rounded
which means a better distribution of the population across all ages
but young people still account for the majority
This indicates that the number of children has already decreased a little,” assesses the demographer
For these young people, the reality they live in is one of racism and lack of access to basic rights such as water, food, sanitation, energy, security and opportunities. The research “Food insecurity among indigenous families in Dourados, Mato Grosso do Sul, Brazil”
identified the prevalence of food insecurity in almost 65% of the families interviewed in the RI.
So there is a great dependence on the city due to this food insecurity
which today has no space to reproduce and plant and even if it is demarcated
today not everyone would have the tools [knowledge] to be able to plant”
Born in the Bororó village, within the Reserve, the doctoral student and Guarani Kaiowá nurse has worked since her adolescence in a youth organization, the Action of the Indigenous Youth of Dourados (AJI)
She also adds that the context of youth in IR is so violent that the demand for territory sometimes ends up taking a back seat to such basic needs
“My grandparents were forcibly brought here
They came from this context of tekoha [village in Guarani] and they have this perception of what tekoha was like and how important the territory is
but today's youth are born in this context of social fragility
The creation of the Reserve in 1917 by the Indian Protection Service (SPI) – an indigenous agency that preceded the National Foundation for Indigenous Peoples (Funai) – was part of a policy of dispossession and confinement of indigenous peoples in Mato Grosso do Sul
established in the early XNUMXth century as an incentive for the colonization of the Center-West
The result was a series of violations and expulsions that took indigenous people from other villages and territories to the then-called Francisco Horta Barbosa Indigenous Post
created by means of a state decree by the governor of the then State of Mato Grosso
without a prior study that guaranteed the connection of the demarcated area with the lands traditionally occupied by them – as guaranteed today by article 231 of the Federal Constitution
Currently, the urban perimeter of Dourados extends over the Reserve, separated only by a ring road, place where at least five indigenous people were run over in recent years, including a child
has a good part of its surroundings occupied by corn and soybean farms
a wall separates it from luxury condominiums
which illustrates the violent relationship between the city of Dourados and the indigenous population
a professor at UFGD and researcher at RAIS
the expansion of the urban perimeter into the Reserve and the occupations in the surrounding area intensified from the 1970s onwards
that condominiums such as Ecoville and Hectares emerged
the urban perimeter of Dourados was expanded and since then
condominiums have been multiplying rapidly
And these luxury condominiums close to the ring road are beginning to build large
high walls that make it impossible for indigenous families who need to leave the Reserve and access the city to work or shop
impacting the movement of indigenous people,” explains the researcher
“It seems that everything in Dourados is now a city
they have almost taken over all the villages
Right in front of our village there were large
And that is where we always used to get wood to build the house of prayer
Then in a short time they burned the forest
they cut it down because they saw many indigenous people getting wood there to build the house
that is what hurts us the most,” lamented Michele Concianza
It is in this context that youth organizations emerge, mobilizing in collectives such as AJI and Resumption of Young Guarani Kaiowá Aty
“Aty Jovem is a way for young people to have knowledge about education
We always discuss this because we are the youth
we are future leaders,” explains the filmmaker
The 9th Guarani Kaiowá Youth Meeting, the last meeting of the collective formed by young people from the Guarani Kaiowá and Guarani Ñandeva peoples from all over Mato Grosso do Sul, took place between July 22nd and 26th, in Taquaperi Indigenous Land, amidst attacks on indigenous people of the Panambi Lagoa Rica Indigenous Land
only 300 managed to arrive at the meeting location
which also brought together leaders of Aty Guasu
the great assembly of the Kaiowá and Guarani peoples
The issues faced by young people inside and outside the Reservation are expressed in songs by the indigenous rap group Brô Mc's
The group formed in 2009 by Charlie Peixoto
Clemerson Batista and Kelvin Mbaretê brings in their rhymes the struggle and resistance of their people
caused our misery and now he looks at me with disgust
they sing in one of the parts of the song “A Vida Que Eu Levo”
Remember: Brô Mc's is the first indigenous rap group to perform at Rock in Rio
Brô Mc's and Lídia Guajajara launch rap in defense of isolated indigenous peoples
“I see that today they have much more access
They also have more access to college and technical courses
this needs to be improved and strengthened so that they can go even further
but we also need to provide support for this understanding of the importance of the struggle of indigenous peoples,” he ponders
Michele Concianza sees her work as a communicator as a way for young people to represent themselves from their perspective and also to support the resistance of her people
“We indigenous people speak about what is real
we speak about events based on the reality of the Guarani Kaiowá people,” she states
also highlighting the importance of indigenous communicators in producing information about other realities beyond the Dourados Reserve
such as the actions to recover lands carried out by the Guarani and Kaiowá people – which are called “reoccupations” by the indigenous movement and have been taking place since the 1970s
“Sometimes when I remember what our relatives do during the reoccupation
the experience of the reoccupation is very difficult
And especially for us Guarani Kaiowá who have suffered many threats
That is why we want to show this through the media
because this is what is most important to us,” he concludes
The most relevant news for you to form your opinion on the socio-environmental agenda
LAST ISSUE
Portugal's Duarte Seabra and the 12-year-old gelding Dourados 2 (Diarado x Cornet Obolensky) won Saturday's CSI4* 1.55m Grand Prix – counting for the Longines Rankings Group A – which concluded the second week of competition at the Doha International Equestrian Tour 2025 at the equestrian venue Al Shaqab in Doha
Stopping the clock on 39.03 seconds in a jump-off between five horse-and-rider combinations
Seabra and Dourados 2 bested a field of 32 starters – taking the win ahead of last weekend's Grand Prix winner Gerfried Puck (AUT) and Equitron Naxcel V (Balou du Rouet x Landetto) in second in 39.75
Janne Friederike Meyer-Zimmermann (GER) and Iron Dames Dubai du Cedre (Baloubet du Rouet x Diamant de Semilly) completed the podium with a fence down in 38.97 seconds
Mariano Martinez Bastida (ESP) and Jup (Carrera VDL x Siverstone) finished fourth
followed by Torben Köhlbrandt (GER) on Mastermind RL (Mylord Carthago x Alcatraz) in fifth.
© 2025 World of Showjumping - All rights reserved
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The indigenous population located in the central region of Brazil
is the second largest in terms of population size in the country
The Indigenous Reserve of Dourados has risk factors that increase the vulnerability of the indigenous population to infectious diseases
a neglected disease with high prevalence in priority populations in developing countries
The virus can also cause many more severe diseases
We estimated the prevalence of anti-HSV-1 antibodies and correlated it with the demographic and behavioral characteristics of the Indigenous population of the Jaguapirú and Bororó villages (Dourados
Using anti-HSV-1 (Gg1) IgM and anti-HSV-1 (gG1) IgG Euroimmun and the detection and quantification of HSV-1 viral load in plasma samples
The maps were constructed using QGIS and the statistical analyses using R Studio software
A total of 1138 individuals (> 18 years old) were enrolled
The prevalence of anti-HSV-1 IgM and IgG were 20% and 97.5%
The prevalence of anti-HSV-1 antibodies for IgG was higher in both sexes
Anti-HSV-1 IgM antibodies were present in 17.1%
and 22% of the participants with urinary problems
Real-time PCR was used for confirmatory testing; HSV-1 DNA was detected in 25.6% (54/211) of anti-HSV1 IgM-positive samples
Viral loads ranged from 5.99E + 02 to 3.36E + 13
The seroprevalence of HSV-1 IgM and detection of HSV-1 DNA in the Indigenous population confirmed high silent prevalence
the seroprevalence of HSV-1 in the Indigenous population was higher than that reported in the general adult Brazilian population
and health and sexual behaviors could contribute to the facilitation of HSV-1 transmission in the Indigenous population
Our results may help develop culturally appropriate intervention programs that eliminate health access barriers and improve the implementation of public health policies aimed at promoting information regarding the prevention
and control of HSV-1 infection in Brazilian Indigenous populations
We aimed to estimate the prevalence and analyze factors associated with HSV-1 infection in the Indigenous population of the Dourados/MS Reserve using HSV-1 antibody from participants in the Jaguapirú and Bororó villages
Our research is useful for developing culturally appropriate programs that can facilitate access to public health services
eliminate stigmas regarding HSV-1 transmission and treatment
and support the implementation of public health policies to promote the prevention
and control of HSV-1 infections in the Brazilian Indigenous population
All participants provided informed consent before participating in the study
The study adhered to the principles of the Declaration of Helsinki
Approval was received from the Ethics Committee of the University of Grande Dourados (UFGD-MS) in March 2017 (CA AE:62012616.3.0000.5160 (number 2.000.496))
This study was conducted with utmost professionalism and care
ensuring that all doubts and concerns were addressed promptly
The Dourados Indigenous Area Health Team (EMSI
1 and 2) provided multidisciplinary expertise and support for this study
Our sampling team of doctors and nurses q1the use of sterile equipment and needles for venous blood draws
a team of skilled health professionals consisting of medical doctors
with the assistance of a proficient local interpreter
collected data and blood samples from the Indigenous population from two villages in Dourados
The research population was made up exclusively of indigenous adults aged 18 or over who were able to provide informed consent
each individual voluntarily signed a comprehensive consent form and responded to a personalized socio-epidemiological survey
ensuring an optimal level of privacy and anonymity
To further validate our structured questionnaire
we sought input from Indigenous health professionals and an Indigenous health agent translated the questionnaire into the native language when needed
The questionnaire-based interview aimed to capture a comprehensive profile of the participants
focusing on their risks and protective factors
We carefully selected information on risk behaviors for HIV and HBV
including sociodemographic information such as income
and signs and symptoms of hepatitis B and C
The study included consenting individuals aged 18 years who resided in the study area
Participants who failed to provide sufficient blood samples for anti-HSV-1 testing were excluded
The study population was determined using data from the Special Indigenous Health District of Mato Grosso do Sul (SIHD/MS)
there are 13,094 Indigenous individuals residing in Bororó and Jaguapirú within the Dourados/MS municipality
the estimated eligible population for sampling was 3400
The selection criterion for the regression analysis to calculate the p-value
the POR (95% CI) above 0.20 was statistically calculated
The eligible sample size for our study included 295 individuals
We recruited 1,168 study participants over the age of 18 who agreed to take part in the survey; the remainder did not agree to take part in the survey
around four times more than the estimated sample size required
This represents 8.9% of the total population living in the Dourados Indigenous Reserve/MS
Anti-HSV-1 (gG1) IgM and anti-HSV-1 (gG1) IgG Euroimmun (Euroimmun
Medizinische labordiagnostika AG-Germany: Anti-HSV-1 (gG1) ELISA (IgM) order no
EI 2531-9601-2 M LOTE: E180321AT and Anti-HSV-1 (gG1) ELISA (IgG) order no
El 2531-9601-2 G LOTE: E220906BL) ELISA (enzyme-linked immunosorbent assays) detected serological markers of HSV-1 infection
The sensitivity and specificity of both immunoassays were determined according to the manufacturer’s instructions using positive
The test had a specificity of 100% and a sensitivity of 100%
The results were assessed using binary outcomes of positive and negative HSV-1 IgG and IgM
The ELISA technique ensured high antigen specificity
which minimized the incidence of false positives due to cross-reactions with anti-HSV-2
it can be concluded that this assay is reliable and accurate as per the protocol
Information was categorized into distinct categories
Block B covered sociodemographic information
Block C delved into the history of drug and alcohol usage
The participants responded to the questionnaires in a “yes” or “no” format
This questionnaire was validated by the Ethics Committee of the UFGD-MS and is included in Supplementary Information
were analyzed using Pearson’s chi-square test to evaluate their correlation with serological status
and the prevalence odds ratio (POR) were estimated to determine the association between sociodemographic variables and HSV-1 positivity among Indigenous people
and HSV-1 infection using Pearson’s chi-square test
Logistic regression was used to estimate the Prevalence odds Ratio (POR)
The significance level was set at p < 0.05
Analyses were performed using RStudio software (version 2023.03.0)
Maps were constructed using QGIS (version 3.26.1)
The distribution of HSV-1 positivity and negativity corresponding to age
where the mean age at infection was 30 years (interquartile range 22.40) years
with the highest HSV-1 prevalence between 29 and 39 years
Distribution of anti-HSV-1 IgG positive and negative prevalence in Bororó (right) and Jaguapirú (left) villages (Dourados
The prevalence of anti-HSV-1 IgG in Indigenous people who declared to be retired was 97%
lived in another village previously was 97.7%
The use of cell phones to access health information was reported in 76.5% of participants
in which the HSV-1 IgG prevalence was 97% (POR = 0.23 (0.03–0.79); p < 0.05)
Internet use was reported in 21.7% (POR = 0.51 (0.24–1.17) with an HSV-1 IgG prevalence of 96.1%
In participants that did not use cell phones or internet to access health information
more than half of the participants used television (52%)
Positive and negative outcomes for anti-HSV-1 IgG serological tests among Indigenous Guarani-Kaiowá and Terena ethnicities and their geographical locations in Mato Grosso do Sul
The prevalence of anti-HSV-1 IgG was found to be significantly influenced by Indigenous educational background. The prevalence in illiterate and elementary-educated participants was 98.2% (846/861) (POR = 1.14 (0.17–4.23), high-school-educated was 96.1% (246/256) (POR = 0.49(0.07–1.90) and college-educated was 92.2% (47/51) (POR = 0.23 (0.03–1.24) (Table 1)
observing a decrease in the prevalence according to the educational level
and therefore a protective factor with higher educational levels
Families earning > 5 minimum wages had a 100% prevalence of anti-HSV-1 IgG (10/10) accounting for 0.9% of the total Indigenous population; families earning < 1 minimum wages was 97.4% (666/684%)
representing more than half of Indigenous population (58.8%); families earning 1–2 minimum wages was 98.6% (416/422) (POR = 1.87 (0.77–5.2); and families earning > 3 minimum wages was 92% (57/62) (POR = 0.25 (0.09–0.79)
Indigenous people who worked formally or informally tested 97.9% for anti-HSV-1 IgG
Among those who reported condom use behaviors, the prevalence was 14.1% in those who reported ‘always’ used (POR = 0.35 (0.16–0.82), and 85.9% in those who reported ‘sometimes’ or ‘never’ used. In addition, the prevalences in those with risky behaviors and drug and alcohol history are reported in Table 1
The difference in prevalence for former prisoners
and blood transfusions were not statistically significant
sexual intercourse with a partner who was an injection drug user
sexual intercourse with a partner who is an injecting drug user
the prevalence of anti-HSV-1 IgG with respect to sexual preference was 100% in homosexual and 97.6% in heterosexual individuals
Although certain groups may have had higher prevalence rates
these differences were not statistically significant
In Table 2
the Guarani-Kaiowá ethnic group showed the highest rates of illiteracy (60.8%) and elementary school education (73.3%)
which were different from the Guarani-Nhandeva and Terena ethnic groups
where the highest rates of college education were 35.3% and 3.9%
the Guarani-Kaiowá ethnic group had the highest rate with < 1 minimum wage (73.8%)
and the Guarani-Nhandeva and Terena ethnic groups had the highest rates of income of 3–4 minimum wages (36.5%) and five minimum wages (10%)
The Guarani-Kaiowá ethnic group had the lowest income and educational level
HSV-1 among residents of the Bororó and Jaguapirú villages in Dourados
a high percentage (97.5%) of Indigenous Brazilian people residing in Dourados
our research indicates that the prevalence of HSV-1 IgG antibodies is notably similar between the sexes
with females displaying a higher percentage (97.6%) compared to males (97.3%)
It was observed that the majority of the people included in the study were women 80.9% (945/1168)
This is due to the demographic location of the villages being located in difficult access to work
the social phenomenon on the days when the questionnaires were administered and the blood samples were taken
who are the financial providers of the household
were out of the villages due to work or hunting
The results of our study indicated that the prevalence of anti-HSV-1 IgG among the Guarani-Kaiowá and Terena ethnicities was 98.3% and 96%
with odds ratios of 2.53 (1.2–5.42) and 0.51 (0.23–1.2)
the prevalence of anti-HSV-1 IgG in other ethnicities was 82.1%
Our findings suggest that individuals belonging to the Guarani-Kaiowá ethnicity are at a significantly higher risk of acquiring HSV-1 than those belonging to other ethnic groups in the study and are more numerous in the Bororo (72.3%; 405/560) village than in the Jaguapirú village (27.6%; 155/560)
HSV-1 was more prevalent in the Terena ethnic group in the Jaguapirú village (88%; 92/104) than in the Bororo village (13%; 12/104)
These variables may be linked to the increased prevalence of HSV-1 infection in this vulnerable community
Further research is necessary to unravel the specific underlying factors that contribute to HSV-1 acquisition in this group
The prevalence of anti-HSV-1 IgG among Indigenous individuals moving between villages was 97%
compared to those who refrained from travelling and migration
the risk of having anti-HSV-1 IgG was only 3% greater which was not statistically significant
indicating a significantly high prevalence (100%) for HSV-1 in the indigenous homosexual population in Brazil
These findings contribute to a better understanding of the impact of sexual preference on the prevalence of HSV-1 and can guide and prioritize future preventive measures
the scope of this study was constrained due to the scarcity of blood samples required for molecular and phylogenetic analysis
These precious materials were procured from populations that are notoriously hard to reach
contributing to the challenges faced during our investigation
The prevalence of HSV-1 in Indigenous populations was significantly higher (97.5%) than in the general adult Brazilian population (70.1%)
Our study also identified a high incidence of HSV-1 infection and circulation of HSV-1 DNA within the Jaguapirú and Bororú village populations
The discovery of HSV-1 IgM suggests that reactivation or primary infection of HSV-1 may have caused an outbreak of the virus in the Bororó and Jaguapirú Indigenous populations
It is important to emphasize that HSV-1 is a latent virus that can be reactivated and
widespread and disseminated HSV-1 infections can lead to high mortality rates in high-risk groups
and drug use contribute to the increased HSV-1 prevalence in Indigenous population in Brazil
culturally appropriate intervention programs are necessary to eliminate health access barriers faced by Indigenous populations
public health policies should aim to promote information on HSV-1 infections and therapeutically prevent and control the virus among the Indigenous populations in Brazil
Achieving these goals requires a respectful and culturally sensitive approach
including the promotion of appropriate condom usage
Our research offers valuable insights into the prevalence and potential risk factors contributing to HSV-1 infections among Indigenous populations in Brazil
providing more effective public health policies and interventions
it is important to acknowledge that the health requirements and susceptibilities of Indigenous Peoples are diverse
given that they represent unique and multifaceted communities inhabiting varying environmental and social conditions
The data presented in this study are available upon request from the corresponding author
All the data from this study are reported in this article
Special Indigenous Health District of Mato Grosso do Sul
HEALTH ASSEMBLY World Health Organization (WHO)
The health of Indigenous PeoplesDraft resolution proposed by Australia
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a percepção do suicídio como inseparável das outras formas de violência segundo os/as jovens indígenas: um estudo de caso da Reserva Indígena De Dourados
Reserva Indígena de Dourados: Histórias e Desafios Contemporâneos
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High prevalence of human T-lymphotropic virus 2 (HTLV-2) infection in villages of the Xikrin tribe (Kayapo)
Epidemiological aspects of HIV infection and AIDS among indigenous populations
Molecular epidemiology of human T-lymphotropic virus type II infection in Amerindian and urban populations of the Amazon region of Brazil
Analyzing STD and aids control policies among Brazilian indigenous population
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High prevalence of sexually transmitted infections
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Increasing proportion of herpes simplex virus type 1 as a cause of genital herpes infection in college students
Chromatin dynamics during herpes simplex virus-1 lytic infection
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Herpes simplex Virus-1 in the brain: the Dark side of a sneaky infection
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We thank all participants for their contributions to our study
This study was financed by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior—Brasil (CAPES)—Finance Code 001
Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ)
Oswaldo Cruz Institute and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) and partially funded by Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq Grants 440245/2018-4)
Fundação de Apoio ao Desenvolvimento do Ensino
Ciência e Tecnologia do Estado de Mato Grosso do Sul (FUNDECT 041/2017)
and Secretaria do Estado de Saúde of Mato Grosso do Sul
Molecular Virology and Parasitology Laboratory
Ana Carolina Silva Guimarães & Vanessa Salete de Paula
Department of Epidemiology of Microbial Diseases
Universidade Federal de Mato Grosso do Sul-UFMS
Sabrina Weis-Torres & Ana Rita Coimbra Motta-Castro
State Department of Health of Mato Grosso do Sul
Crhistinne Cavalheiro Maymone Gonçalves & Ana Rita Coimbra Motta-Castro
Federal University of Grande Dourados (UFGD)
S.R.d.S.; L.F.T.L and F.F.d.O.B.; investigation
and V.S.d.P.; writing?original draft preparation
F.F.d.O.B.; writing review and editing; supervision
All authors have read and agreed to the published version of the manuscript
Approval was received from the Ethics Committee of the University of Grande Dourados (UFGD-MS) in March 2017 (CA AE:62012616.3.0000.5160 (number 2.000.496))
Informed consent was obtained from all participants involved in the study
The authors declare no competing interests
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations
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Eli Dourado is a senior research fellow at the Center for Growth and Opportunity at Utah State University
His work focuses on identifying and eliminating the barriers to the hard technology innovations needed to drive large increases in economic growth
He has worked on a wide range of technology policy issues
His popular writing has appeared in The New York Times
Eli was the first policy hire at a supersonic aviation startup
he was a senior research fellow at the Mercatus Center at George Mason University and director of its technology policy program
He received a PhD in economics from George Mason University and a BA in economics and political science from Furman University
Now is the time for the NIA to drive science-first funding for the field of aging
The giant 90-meter-wide DOURADO barge successfully crosses the Suez Canal - SCA
Each week, Atlas Obscura is providing a new short excerpt from our upcoming book, Wild Life: An Explorer’s Guide to the World’s Living Wonders (September 17
whose name is Portuguese for “golden grass,” shine like they’re spun out of a fairy tale
Artisans in the Brazilian Cerrado use capim dourado to weave everything from gleaming hats and baskets to luminous
capim dourado is a double misnomer: It’s not gold
“Golden grass” is actually the long stems of a small desert flower known as sempre viva
Lent its flash by the aluminum-rich soil in which it grows
the plant spends much of the year as a small rosette of leaves hunkered close to the ground
But every July—springtime in the Cerrado—the flower stalk shoots up 2 feet (60 cm)
it’s standing tall among the other grasses
glinting until it catches someone’s eye
capim dourado is perhaps brightest in Jalapão
where the Mumbuca community has been harvesting it for nearly a century
Husbandry of the wild plant involves regular controlled burning
which keeps the crowded grass canopy open so that sunlight can reach the rosette
does its part by trapping humid air between the folds of its leaves
which improves its chance of survival during a blaze
and people was nearly undone by the success of capim dourado crafts
When demand for the golden goods skyrocketed in Brazil in the early 2000s
a new wave of harvesters unfamiliar with the environment poured in
the local communities and government called on scientists to help maintain the balance
The researchers helped establish timing that allows the plant to complete its life cycle before it donates its stalk to beauty
“When you harvest it and it’s dry
the [rest of the] plant stays on the ground
you’re going to take the plant with you,” says botanist Isabel Belloni Schmidt
A state law issued in 2019 forbids harvesting capim dourado before September 20 each year
giving the plant enough time to mature and fully dry out
the Mumbuca community of Jalapão began a new tradition: a festival that ushers in the harvesting season
During the Festa da Colheita do Capim Dourado
and to be dazzled by the latest ways in which weavers have transformed this beloved material
Species: Capim dourado (Syngonanthus nitens)
How to see it: This plant grows throughout the Cerrado
but handicrafts made with it are sold in Brazilian cities beyond the grasslands
Nubia Matos da Silva is a journalism student
a Quilombo community in Jalapão State Park
Members of the Mumbuca are descended from African people who did not accept the conditions imposed on them after they arrived in Brazil
instead choosing to build their own way of life in the Cerrado
Nubia’s family has been weaving with capim dourado for four generations
a part of the savanna where the grass grows low to the ground and the earth is very wet
an area with larger trees that grow along the river
I have heard of people who tried to grow capim dourado from seeds
but it never worked because it did not produce its golden color
How long has your community been harvesting capim dourado
There are no records of how long our community has been harvesting capim dourado
since the people here never thought about recording the times and events
But I can say that it is since the time of my great-grandmother Laurina
She was walking through the green field when she noticed something shining
and she thought that she could do something with that shining grass
She picked some of this grass and showed it to her husband
Then she made the first craft ever made with capim dourado—a hat that she gave to her husband to protect him from the sun
We can make capim dourado crafts for the kitchen for decorations
Are there risks of harvesting capim dourado
If it is harvested before the correct time
That is why we need to emphasize that capim dourado can only be harvested after September 20
This practice is respected by the community
What value does capim dourado have to your community
it takes me back to my grandmother and my aunts
and I think about everything that capim dourado gave to us
Many people walked on this grass thinking nothing of it
but my great-grandmother saw its importance and saw that that grass could give us things that would be inaccessible without it
capim dourado is one of the main sources of revenue
Capim dourado does not only have a monetary value
it has a sentimental value and a cultural value
I remember my loved ones who are not here anymore
but who have left us something so precious that it makes us remember always all the possibilities nature has to give us
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The city of Dourados in Brazil's Mato Grosso del Sul state yesterday became the country's first to launch a mass dengue vaccination campaign
In a prefecture statement today
officials said 537 doses were given on the first day of the campaign
which was developed by the municipal health department in a partnership with Takeda
Targeting 150,000 people between ages 4 and 59 years old
the dengue vaccine will be administered in two doses
"Dourados has been an example for the entire country
vaccination strengthens individual defenses and also contributes to building a collective barrier against the spread of dengue."
Brazilian drug regulators approved the Takeda vaccine in March 2023
is built on a serotype 2 backbone and targets all four dengue serotypes
In a clinical cohort study
only 31.9% of high-risk adult COVID-19 outpatients were prescribed an antiviral drug
which the researchers said underscores the need to identify and reduce treatment barriers
A team led by scientists from the California genomics firm Helix analyzed electronic health records from two healthcare systems in Minnesota and Nevada to determine prescribing patterns of nirmatrelvir-ritonavir (Paxlovid)
and remdesivir among 3,247 high-risk COVID-19 patients from April 2022 to June 2023
The findings were published yesterday in Clinical Infectious Diseases
31.9% of patients were prescribed a COVID-19 antiviral
the most common of which was Paxlovid (87.6%)
followed by molnupiravir (11.9%) and remdesivir (0.5%)
The vast majority of patients were given their prescription on either the day they tested positive (30.3%) or the day after (56.3%)
The prescribing rate rose slightly over time
The proportion of patients with underlying conditions prescribed an antiviral was 32.2% to 42.6%
The percentage of patients with Charlson Comorbidity Index (CCI) scores of 1
There is a need to identify and address treatment barriers and raise awareness and understanding among providers and patients around oral antiviral eligibility
Antiviral prescribing rates were similar for adults aged 65 and older (39.6%)
including those with chronic lung disease (39.8%) or a weakened immune system (43.0%)
Of the 1,732 patients (53.3%) with symptoms
prescribing was not meaningfully different overall (35.4% vs 27.9%) among asymptomatic patients or those 65 and older (42.6%)
Ages 50 to 64 years and 65 and older (vs 18 to 49); asthma
or 3-4 (vs 0) were significantly tied to a higher likelihood of prescription
unvaccinated status (vs vaccinated 0 to 5 months earlier) and having an emergency department or laboratory-only (vs outpatient) visit or chronic kidney disease were significantly linked to lower chances of prescription
"There is a need to identify and address treatment barriers and raise awareness and understanding among providers and patients around oral antiviral eligibility
New Jersey meat processor Fratelli Beretta USA has recalled about 11,000 pounds of its Busseto Food brand ready-to-eat charcuterie products after the Minnesota Department of Agriculture detected Salmonella in a product sample
In a recall notice
the US Department of Agriculture (USDA) Food Safety Inspection Service (FSIS) said it is working with the Centers for Disease Control and Prevention and state health partners to investigate a multistate Salmonella outbreak
The positive sample that Minnesota officials found came from an unopened product sample as part of an illness investigation
On January 2, the Minnesota Department of Health (MDH) said one Minnesotan got sick in December after eating a Busseto brand charcuterie sample bought at Sam's Club
since many patients infected with Salmonella don't seek medical care
the number of affected people is likely to be higher
The FSIS recall notice said the sampler pack was produced on October 30
and was sold as a twin-pack containing two 9-ounce trays containing prosciutto
and dry coppa with the lot code L075330300 and best-if-used-by date of April 27
Products subject to the recall were shipped to Sam's Club distribution centers in eight states: Georgia
The FSIS said it is concerned that the products may still be in customer's refrigerators
It urged people not to consume them and to throw the products away or return them to the place of purchase
Most US hospitals now meet the antibiotic stewardship standards set by the Centers for Disease Control and Prevention (CDC), according to a paper published today in Open Forum Infectious Diseases
Using data from the National Healthcare Safety Network Annual Hospital Survey, CDC researchers found that 95% of US acute care hospitals reported using all seven of the CDC's Core Elements of Hospital Antibiotic Stewardship Programs (ASPs)
uptake has been highest in large and teaching hospitals and lowest in small
The CDC has been monitoring uptake of the core elements—hospital leadership commitment
and education—since they were published in 2014
The CDC's objective was to help hospitals develop ASPs by outlining the structural and procedural components associated with successful programs
While only 10% of hospitals reported uptake of all six Priority Elements
which highlight a subset of ASP implementation approaches considered highly effective by experts
46% of hospitals reported uptake of four or five of those elements
91% of hospitals reported monitoring antibiotic resistance patterns at least annually
and 74% said they tracked antibiotic use at least quarterly
The CDC noted that hospitals have also made progress on uptake of recommended best practices
with 76% reporting implementation of prospective audit and feedback and 64% reporting that their ASP was co-led by a physician and pharmacist in 2021 (up from 23% in 2015)
the percentage of ASPs that had a formal statement of support from hospital leadership rose from 53% to 97%
the authors of the paper note that there has not yet been convincing evidence at the national level that increased implementation of the core elements has improved antibiotic use (AU) in US hospitals
"The data in this report demonstrate that US hospitals have built a strong foundation for antibiotic stewardship," they wrote
"Our goal must now be to translate that infrastructure into even more effective interventions to improve AU."
A new report by British members of parliament (MPs) is calling on the UK government to address issues hampering research and development of bacteriophage therapy
which are viruses that target and kill bacteria
has grown in recent years amid the global rise in antimicrobial resistance (AMR) and the weak pipeline for new antibiotics
But the report from the House of Commons Science
Innovation and Technology Committee says their potential as a treatment for drug-resistant infections in the United Kingdom can't be fully realized
because most UK and imported phages have not been manufactured to meet the required Good Manufacturing Process (GMP) standards and therefore can't be used in clinical trials or compassionate use cases
The committee says this issue has hindered attempts to conduct research of phage safety and efficacy
and integrate phage therapy into the UK health system
the report says the UK Department for Health and Social Care (DHSC) should bring together funders and innovation centers to build a GMP facility that can be used by phage researchers and developers
"Such research could harness the UK's genomic research prowess and artificial intelligence to match phages to bacteria and allow manipulation to increase effectiveness," the committee wrote
the committee argues that the government should allow compassionate use of non-GMP phages produced in the UK for last-resort medical cases
which is based on interviews and written evidence submitted by phage researchers and AMR experts
also calls for a dialogue between phage researchers
and other UK health agencies on what specific evidence is needed to fully assess the safety and efficacy of phages; identification of bottlenecks for phage transitional research; an annual report on the progress made in all phage-related technologies; inclusion of information about the clinical use of phages within medical training; and guidance on how phages will be regulated
the Government should produce a clear statement on the role that phages could play in fighting AMR and how they will be supported," the report states
Global Virus Network scientists highlight the need for robust surveillance
and readiness for potential human-to-human viral transmission
only the severe infections continued to cause symptoms.
The Biden-era rule would have prevented the sale of raw chicken or turkey with certain levels or strains of Salmonella
and 83% of infections are part of outbreaks
Almost 90% of the European cases were reported in Romania
The study identified open-space development and low population density as risk factors for Alpha-gal syndrome.
The Wall Street Journal reports the Trump administration is investing $500 million in the universal vaccine project
There are currently 59 herds quarantined in 4 Idaho counties
The CDC today addressed what's known about treatments pushed by Kennedy
urging caution about vitamin A use and citing individual decision-making by heath providers for others
Some of the key steps have included deployment of more community health workers and decentralized lab testing
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states that Women are essential in the fight against the outbreak – as first responders
as well as being disproportionately affected by the crisis.Ensuring the gender dimension in the response requires specific resources targeted to meet the needs of women and girls
Women’s organizations at the community level should be supported to ensure that messages about prevention and response strategies reach all women
Copyright © UN Women
the giant floating dock “DOURADO,” has successfully sailed through the Suez Canal waterway
we now face the possibility of a supply-induced recession
the likes of which we haven’t experienced since the oil shocks of the 1970s
The war in Ukraine and the spread of the Omicron variant of Covid-19 in China could hit supply chains and production capabilities in the U.S
leading to the return of stagflation: high inflation and low economic growth at the same time
We need to adjust our economic toolkit to deal with stagflation
While stimulus payments from Congress and the Fed successfully sustained American demand in the face of the global pandemic and averted a much bigger recession
demand-side fiscal and monetary policies won’t be nearly as useful in a supply-shock recession
To minimize the severity of the next recession
we must address the supply-side of the economy directly
China’s struggles to contain Omicron represent a distinct set of shocks
The “Zero Covid” policies the country used successfully to contain the virus thus far do not appear up to the job of fighting off the new variant
Yet with a population protected only by less effective vaccines and virtually no immunity from prior infection
abandoning these policies would unleash a massive wave of Covid cases that would overwhelm Chinese hospitals and increase the disease’s fatality rate
The country is now locking down multiple cities and even entire provinces
Even if these lockdown measures work in the short term
they may need to be reimposed over and over again
absent a new strategy to contain one of the most contagious diseases in history
These repeated lockdowns will hamper China’s ability to contribute to the global economy and its supply chains
Traditional monetary and fiscal policies have limited utility against a supply shock
supply and demand are more interdependent than typical charts let on
so demand-side policies do have a role to play in preventing the supply shock from depressing spending
these conventional macroeconomic policy tools cannot address the shocks we may soon experience
The only solution is to offset the shock to aggregate supply with a boost in the economy’s productive capacity
Without such a compensatory supply-side action
the negative supply shock will increase inflation and hurt economic growth
we can try to undo the specific shocks we are experiencing
we can try to compensate for the reduction in Russian oil supplies with greater domestic oil production
But this kind of response can only go so far
We cannot quickly ramp up the production of wheat
or Chinese manufactured goods to make up for each individual shock
And with the complexity of modern production
even one missing part can bring a factory to a halt
not all these actions will offer relief from the specific supply shocks we could soon face; nor will they all have an immediate effect
doing as much as possible now to remove barriers to productivity and efficiency is our best hope to avoid prolonged stagflation
Eli Dourado is a senior research fellow at the Center for Growth and Opportunity at Utah State University
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The start of 2020 has been marked by a series of attacks against indigenous Kaiowá communities in Brazil’s border region with Paraguay
part of a long-running and increasingly violent campaign for control of their land
a group of as-yet-unidentified invaders set fire to a community house of worship in the village of Laranjeira Nhanderu
leaving the panicked residents searching for water to extinguish the fire
Rio Brilhante is an area where the land is under dispute
the houses of worship are the strongest symbol of a people under constant threat from industry in central-west Brazil
“The Kaiowá make sure to build houses of worship to provide them with more security,” says theologian and historian Graciela Chamorro
this kind of structure guarantees a locale where ‘the word is germinated,’ which makes them imagine that the non-indigenous respect this place.”
A former professor of indigenous history at the Federal University of Grande Dourados (UFGD)
Chamorro has studied the spiritual relations and religious practices of the Kaiowá for more than 30 years
the houses of worship are where ‘the word sleeps,’ where their tradition is kept alive,” she says
With the indigenous community in Rio Brilhante rattled
the signals coming from the authorities have not been encouraging
The land in Laranjeira Nhanderu has not been formally ratified and demarcated
which means the community faces difficulties obtaining basic support
the federal agency in charge of indigenous affairs
It’s not clear who was responsible for setting fire to the Kaiowá house of worship. One of the leaders of the group Aty Guasu, the main Kaiowá political organization, accused non-indigenous people of the attack on the sacred site
But there are also internal rifts within the community in Laranjeira Nhanderu
pitting those who follow the ancestral rites against indigenous members who have converted to Christianity
The reserve, on the outskirts of a municipality of the same name, is one of the oldest and most populous in Brazil
It’s home to more than 15,000 indigenous peoples — including the Kaiowá
Guarani Ñandeva and Terena — living in precarious conditions in on 3,000 hectares (7,400 acres)
In a statement to Mongabay, the Federal Public Ministry said that after the fire in Jaguapiru, a public hearing on religious intolerance was held at the end of November 2019
did not respond to a request for comment by the time this story was published
The symbolism of these attacks comes on top of already arduous challenges to maintaining indigenous traditions in the region
Foremost among them is the expansion of other religious groups
especially Neo-charismatic evangelical churches
new churches emerged in the absence of the Kaiwá [Evangelical Mission],” Chamorro says
“The indigenous people go to the congregations in the cities and then they bring the pastors to the reserve
We don’t know much about where the new churches came from
but they arrived all at once.” She says there are around 100 Neo-charismatic churches in the Dourados Indigenous Reserve alone
their abundance serving to exacerbate the internal rifts within the reserve’s inhabitants
“When I go to the region to talk with leaders and pastors
I ask about [religious] coexistence in the territories
Of course they don’t admit their desire to do away with the traditional practices
that apprehension got to the point that the State Public Ministry of Mato Grosso do Sul state
where both Dourados and Rio Brilhante are located
the ministry developed two “terms of conduct adjustment” (TAC) to ensure that the different congregations respected the traditional indigenous rituals
The documents were signed by representatives from more than 24 churches and called for the observation of “the cultural freedom of the indigenous villages
respecting all the traditional dances and forms of worship.” The TACs also demanded that they participate in “courses for training
orientation and education” with their leaders and pastors to guarantee “religious freedom at the locale where their congregations
facilities and entities are headquartered.”
Later on the same day that the Kaiowá community was fighting put out the fire at the house of worship in Rio Brilhante
another attack flared up on the outskirts of Dourados
Private security guards from nearby ranches mounted an attack on a group of some 100 Kaiowá families
in reclaimed areas within the limits of the indigenous reserve
“Reclaimed” lands are those invaded by indigenous peoples in order to apply pressure for demarcation — a process permitted under the Constitution
but paralyzed by the administration of President Jair Bolsonaro
The group of attackers comprised around 15 armed guards using a modified tractor that the indigenous community called “the big skull.” They also threw a grenade at the villagers; the explosive blew three fingers off the hand of a child who handled it
There are also allegations that the Department of Frontier Operations participated in the offensive
The agency falls under the authority of the Mato Grosso do Sul governor
A committee of representatives from the Federal Public Defender’s Office of the Federal Public Ministry and 18 other civil society organizations visited the area to investigate the accusations
the public defender’s office sent a letter to the governor
requesting an explanation for the incident
The document describes how the committee “confirmed the existence of several 22-caliber shell casings
as well as the presence of indigenous people with gunshot wounds,” and that “there is no doubt that the scenario is one of intense conflict.” Contacted by Mongabay
the Department of Frontier Operations sidestepped the question
said that “if it had not been for the quick intervention [from the Department of Frontier Operations]
more people would have been wounded and perhaps even deceased.” Souza also raised doubts about the victims
saying the department had provided first aid to a “supposedly indigenous person” who had sustained light injuries
adding that “there had been no formal accusation or complaint” about the operation
The state government of Mato Grosso do Sul has not commented
As in Rio Brilhante, the motive for the attack in Dourados is unclear. Some indigenous people blame it on soybean farmers
while suspicion also surrounds others who stand to benefit from their expulsion from the land
the urban area of Dourados municipality has expanded; in 2015
the reserve’s surroundings were included in the city limits
This has translated into intensified real estate speculation
a number of developers have their eye on the land around the reserve
Tensions in Dourados and surrounding areas are mounting, with the Ministry of Justice and Public Safety sending the National Public Security Force to Mato Grosso do Sul
The decision to deploy troops to the municipalities of Dourados and Caarapó for a period of 180 days was published in the Diário Oficial da União
The dispatch of the National Public Security Force is also in response to the spate of killings of Kaiowá there
The murder rate among the indigenous population in Dourados and surrounding areas was more than three times the national average from 2012 to 2014
according to Federal Public Ministry statistics
One of the worst recent spates of violence in Dourados occurred in June 2019: six indigenous people were murdered in the second half of that month alone
land conflicts are the driving force behind the threats to indigenous peoples
and the situation is no different with the Kaiowá
“There are several court cases seeking to establish the ownership of the land [for the indigenous people]
but they take years and wear down the Indians as well as the farmers,” the state Federal Public Ministry said in a statement to Mongabay
It’s mostly farmers encroaching onto their lands
monoculture plantations and large-scale ranches reign in the landscapes near the border with Paraguay
including in Dourados and surrounding areas
the majority of native vegetation [on indigenous lands in the state] has been replaced by pastures and different agricultural crops since the Paraguayan War [in the 19th century],” says Ariel Martins
a professor of environmental engineering and water resources at Mato Grosso do Sul Federal University (UFMS)
Dourados and Ponta Porã” — all regions where indigenous communities have come under attack recently — “are dominated by rice
The exclusive planting of monoculture crops like sugarcane and soybeans exacerbates erosion
leading to a greater loss of soil and a drop in food productivity
today very little remains of what was once a rich meeting place of the Cerrado
there are only meager remnants of native Atlantic Forest
and the farming practices are still largely unsustainable from an environmental point of view
“Oftentimes there is a lack of technical support to enable producers to do the basics
like diversify the agricultural crops on their properties or drain surface water in order to avoid erosion,” Martins says
Soybean farming continues to expand rapidly in the region, according to the Brazilian Institute of Geography and Statistics (IBGE). The area dedicated to soybean farming in Dourados and Rio Brilhante increased by 20,000 and 30,000 hectares (50,000 and 75,000 acres) respectively from 2013 to 2018, according to Municipal Agricultural Production statistics
The value of soybean production more than doubled during this period: Soy plantations in Rio Brilhante produced 252,000 reais ($63,000) of the commodity in 2013
and by 2018 churned out 506,000 reais ($125,000)
the value of the soybean crop in 2013 was an estimated 312,000 reais ($78,000)
soaring to 688,000 reais ($172,000) in 2018
Banner image of the village of Ypoi by Mídia Ninja
The “fortress conservation” model is under pressure in East Africa
as protected areas become battlegrounds over history
and global efforts to halt biodiversity loss
Mongabay’s Special Issue goes beyond the region’s world-renowned safaris to examine how rural communities and governments are reckoning with conservation’s colonial origins
and trying to forge a path forward […]
The dates displayed for an article provide information on when various publication milestones were reached at the journal that has published the article
activities on preceding journals at which the article was previously under consideration are not shown (for instance submission
Biomedicine and PharmacotherapyCitation Excerpt :contribute significant nephroprotective benefits
Due to the presence of these active natural constituents
Spicatus shows considerable potential for kidney stone prevention and treatment
warranting further research into its application in traditional medicine [99]
has demonstrated potential in the prevention and treatment of kidney stones by enhancing urinary parameters
reducing calcium oxalate deposition in the kidneys
and alleviating tissue pathological damage and inflammation [100]
Desmodium styracifolium has also demonstrated potential in reducing calcium oxalate deposits in the kidneys [50] and mitigating the effects of tissue damage caused by crystals due to its anti-inflammatory and antioxidant properties [51]
Journal of EthnopharmacologyCitation Excerpt :The effect of oral administrations of an ethanolic extract (30 and 300 mg/kg) for 60 days protected against oxidative stress in the kidney produced by an atherogenic diet in rats by reducing the levels of hydroperoxides and increasing the level of renal SOD (Lorençone et al.
Oral administration of an ethanolic leaf extract (30
and 300 mg/kg) were evaluated in a model of rhabdomyolysis-induced acute kidney injury by glycerol (10 ml/kg I.M) in Wistar rats
where a nephroprotective effect was observed at the lowest doses (30 mg/kg) by increasing the urinary excretion of total protein
and all of the treated-groups exhibited a reduction of histopathological lesions and significant elevation of the levels of CAT and SOD in the kidneys (Moreno et al.
this study also demonstrated a reduction in crystallization of urinary crystals
with reductions in the size and proportion of monohydrated crystals in urine samples
All content on this site: Copyright © 2025 Elsevier B.V.
Josh and Agnes would both like Tyler to be more concrete: what does an ethics of economic growth maximization demand of us
I suspect Tyler has reasons for preferring to keep Stubborn Attachments in the realm of the abstract
I am happy to give my own views as to what growth maximization actually looks like
But first I want to push back a little on especially Josh’s query
with apologies if I have misunderstood him
Josh is coming to this discussion with certain ideological priors
He sees in the abstract that Tyler has a compelling argument
but he wishes to understand how—concretely—an ethics of growth maximization interacts with his prior ideological commitments
If one accepts Tyler’s premises and his reasoning
even if they sit uncomfortably with one’s prior ideological preferences
who also argues for conclusions which are uncomfortable to many
one ought to find fault with the argument (which is what Tyler has done)
Insofar as we are doing ethics and not aesthetics
one ought not to reject Singer’s conclusions simply because they don’t comport with prior views
That’s also not how we should approach Tyler’s argument
how could we increase economic growth sustainably without violating human rights
Improve individuals’ access to productive efficiencies that arise from urban life
We cannot execute the NIMBYs without rights violations
remove parking minimums and subsidized parking
Our economy would grow much more quickly if more people were able to live in our most productive cities
we often spend years doing environmental impact assessments which cause delays and high costs without actually providing much in the way of environmental protection (they do allow environmental advocates to temporarily hold projects up in court but that is about it)
Drug development costs are raised by a years-long approvals process that perhaps results in safer drugs on average but reduces the total number of drugs brought to market
or automobiles if we had insisted on today’s safety levels during the early days of those technologies’ development—likewise
we should have laxer safety standards for new emerging technologies
Allow many more immigrants to work in wealthy countries
Taking a talented worker from the Central African Republic
obviously will increase global productivity
as we are nowhere near margins where the total quantity of immigration could be destabilizing
Spend fewer resources “showing that we care.” The RAND health insurance experiment famously showed that health insurance leads to more health care consumption but not necessarily to better health outcomes
The Oregon Medicaid health experiment yielded similar results
We also spend a large fraction of all health expenditures in the last year of life
It’s hard to avoid the conclusion that much health spending
we spend a lot of money attempting to educate people at all levels who don’t really want to learn
and we subsidize higher education without regard to the productivity of the selected major
We could be more “heartless” here without harming economic outcomes very much
Some of the resources we currently spend keeping the elderly alive could be used to do research on how to delay or reverse aging
providing enormous benefits to future people as well as to the economy as people with longer healthspans could have a longer productive life with a given amount of training
Nuclear fusion research also strikes me as particularly worthy
we should do more research across the board
Insofar as our current methods of funding basic research are not getting the best results possible
which might involve slaughtering some sacred cows
The United States in particular does an incredible amount of social engineering through its tax code (e.g.
yet it harms growth by necessitating higher marginal rates to pay for the deductions and credits
The tax code could instead tax negative externalities like carbon dioxide emissions first
then do loophole-free Ramsey taxation on the rest of the economy
This would reduce the amount of resources destroyed through taxation
Get rid of inefficient giveaways to particular industries
Let nurse practitioners have a larger scope of practice
Let unbarred entrepreneurs compete with lawyers
Stop regulating cosmeticians and florists altogether
All of these protectionist restrictions provide higher social costs than benefits
Although it may be possible to quibble with any of the items on my list
at least to my mind it seems that we are very far away from growth maximization
I wonder if Josh and Agnes accept this conclusion
this partial list shows that although Tyler’s framework imposes some ethical demands on individuals (don’t be a NIMBY)
the ways to improve growth involve some level of collective action
It is our collective institutions that are failing us
Tyler’s framework may not be as ethically demanding as Peter Singer’s
but it is quite radical and foreign to western societies on a collective level
Tyler Cowen looks at the place of economic growth in philosophy and public policy
He finds it’s an underexamined subject
sustainable improvements to long-term economic growth
these seemingly trivial changes will prove in the long term to be among the most important choices we make today
Cowen therefore argues for giving greater weight to the longer term
Kim argues for public education and a higher minimum wage
challenging the advocates of economic growth to make the case against them
Although Kim agrees that economic growth matters
he is skeptical that providing social welfare today is liable to slow economic growth
and he calls on Cowen and others to justify this part of their argument
Agnes Callard sees Tyler Cowen as engaged with the classic utilitarian argument for radical wealth redistribution: since spatial differences don’t have moral significance
and the marginal value of our wealth is much higher in the hands of someone crushed by poverty
we should relinquish what we have until that marginal difference disappears
She frames Cowen’s response to this argument in terms of two claims: the similarly arbitrary character of temporal differences
and the utilitarian value of economic growth
When we consider the welfare of future human beings
together with the power of economic growth to raise all boats
then this utilitarian argument becomes an argument for the status quo
Economic growth is fundamental to human well-being
says Eli Dourado; why have ethicists neglected it
He answers that much philosophy was produced when economic growth was either nonexistent or difficult to notice
Even modern ethicists may need to take stock of the world around him
and he closes by praising the beauty of economic growth
Cato Unbound is a forum for the discussion of diverse and often controversial ideas and opinions
The views expressed on the website belong to their authors alone and do not necessarily reflect the views of the staff or supporters of the Cato Institute
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I take the core claim of Tyler Cowen’s Stubborn Attachments to be that a deep concern for maximizing sustainable economic growth
should be an essential element of any system of ethics that purports to care about universal human well-being
Growth is so fundamental to human well-being
both directly and through correlation with other plural values
that this claim hardly strikes me as controversial
and the reason why Stubborn Attachments is such a refreshing contrast
is that so many ethicists have neglected any consideration of economic growth whatsoever
taking the productive powers of the economy for granted
and other ancient philosophers perhaps had an excuse
living standards were similar from century to century
Improvements in productivity led to higher populations (themselves a good thing) but not usually to substantially more per-capita wealth
It would have required extraordinary powers of perception for the ancient Greeks to understand the underlying economics
which were not discovered until much later
The Wealth of Nations could not have been written until the wealth of nations actually started to significantly diverge
the economy in some portions of the world underwent a phase change
Industrialization gave rise to sustained improvement in living standards
with growth suddenly a highly visible phenomenon
moral philosophers do not have the ancients’ excuse
While we are always learning more about economic growth
the benefit of economic growth on the quality of human lives is now well understood to be dramatic
Half a billion years later, around 541 million years ago, things really got going. In the early Cambrian period the number of species exploded. Over a period of around 100 million years, the diverse range of plant and animal life that we know today emerged. Dinosaurs lived, and then were wiped out, except for the ones that were ancestors of today’s birds and crocodiles.
Tyler Cowen looks at the place of economic growth in philosophy and public policy. He finds it’s an underexamined subject. But if we really can make small, sustainable improvements to long-term economic growth, these seemingly trivial changes will prove in the long term to be among the most important choices we make today. Cowen therefore argues for giving greater weight to the longer term.
Joshua M. Kim argues for public education and a higher minimum wage, challenging the advocates of economic growth to make the case against them. Although Kim agrees that economic growth matters, he is skeptical that providing social welfare today is liable to slow economic growth, and he calls on Cowen and others to justify this part of their argument.
Economic growth is fundamental to human well-being, says Eli Dourado; why have ethicists neglected it? He answers that much philosophy was produced when economic growth was either nonexistent or difficult to notice. Even modern ethicists may need to take stock of the world around him, he suggests, and he closes by praising the beauty of economic growth.
Cato Unbound is a forum for the discussion of diverse and often controversial ideas and opinions. The views expressed on the website belong to their authors alone and do not necessarily reflect the views of the staff or supporters of the Cato Institute.
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Three-year-old Sandriely cries in front of the hut where she lived before it was destroyed by a fire set by an unknown arsonist. It was part of a makeshift camp, home to an indigenous Guarani Kaiowa community living squeezed between a highway and their ancestral land.
The attack came as members of Brazil's Guarani tribe are suffering from an increasingly bloody conflict with farmers over traditional territory.
This hut is part of a Guarani Kaiowa makeshift camp, sandwiched between highway BR 463 and their ancestral land, known as Tekoha Apika'y. Members of the indigenous group have been living here since 2009, after they failed to take back the territory from farmers.
The Guarani community as a whole, with a population of around 50,000 divided among the Kaiowa, Ñandeva, and Ava sub-groups, is suffering greatly from an on-going and bitter struggle to return to their traditional territories.
The conflict has the characteristics of a land war, in spite of Brazil's indigenous policy being considered one of the most progressive in the world.
Guarani Ava spiritual leaders perform a healing ritual in a house of prayer on their ancestral territory, which they call Tekoha Yvoh'y.
Despite the Guarani population’s struggle over land, they have managed to preserve their native language and their religion, practiced regularly in rituals and collective prayers.
Guarani Kaiowa woman Dilcia Lopes and her children live in the ramshackle camp on the strip of land between highway BR 463 and their ancestral territory, which they call Tekoha Apika'y.
Dilcia Lopes and her children watch a truck pass by on the highway.
A banner hung by a group of Guarani Kaiowa reads, "Enough of killing indigenous," on the edge of ancestral territory known to them as Tekoha Ita'y. Last April a farmer who occupied part of their land attacked them, but died in the confrontation.
Amnesty International's Secretary General, Salil Shetty (3rd left, dark blue shirt), meets with members of the Guarani Kaiowa community at the makeshift camp where they live.
Amarilda Carvalinda, a 35-year-old Guarani Kaiowa woman, stands in her home.
Paulina Takua Rokavy (right), a member of the Guarani Ava group, teaches children in an improvised school on the edge of ancestral land known to them as Tekoha Yvoh'y.
Guarani Ava children have a lunch of peanuts and chica, a drink made from cassava, at their home.
Guarani Kaiowa children swim in a pond next to a highway that runs past their historic territory, called Tekoha Boqueron.
A Guarani Kaiowa boy stands in front of his makeshift home on the edge of the ancestral land they call Tekoha Takuara. The group's chief, Marcos Veron, was shot to death in 2003.
Guarani Kaiowa tribespeople gather at the place where Denilson Barbosa, a 15-year-old member of their group, was killed by a farmer.
Guarani Kaiowa people gather at the cross marking the place where 15-year-old Barbosa was killed.
A Guarani Kaiowa boy walks past roadside vegetation after a fire set by an unknown arsonist ravaged their makeshift camp.
Members of the Guarani Kaiowa community look at their hut, which was destroyed by a fire near their ancestral land called Tekoha Apika'y.
Relatives of assassinated Guarani leaders attend this year's Aty Guasu, or Great Assembly, that brings together their chiefs and spiritual leaders in Jaguapiru village, Mato Grosso do Sul state.
Guarani leaders and chiefs raise their Mbarak, a type of traditional rattle, during what they called a "war cry for justice and land" during the Aty Guasu.
Guarani chief Getulio Potyvera sits inside the house of prayer on an ancestral land plot known as Tekoha Mykureati.
Guarani spiritual leaders perform the Mita Kara'i, a kind of baptism when children receive their native name and others have their spiritual protection renewed, during the Aty Guasu.
A Guarani Ava child lights a ceremonial pipe called a Petygua, used to ward off bad spirits, during a ritual as the group prepares to take back an ancestral plot called Tekoha Yvoh'y.
A Guarani Kaiowa woman stands watch near their makeshift camp on the edge of ancestral land known as Tekoha Takuara, where chief Marcos Veron was killed in 2003.
Three-year-old Sandriely has a look of suffering. She was born in a roadside camp along the same highway where her brother was run over by a truck. Her grandmother Damiana Cavanha, one of the few women chiefs among the Guarani Indians, has lost, beside her grandson, five other family members: one aunt died of poisoning from pesticides used on the neighbouring sugar cane plantation, and her husband and three of their children were hit and killed by passing vehicles.
Damiana, Sandriely, and 23 other Guarani Kaiowa Indians have been living in a makeshift camp along the shoulder of highway BR-463 in Mato Grosso do Sul since 2009. They settled here after their last failed attempt to take back their ancestral land, called Tekoha Apika’y. Tekohá is loosely translated as ancestral land, and Apika’y, the name of that specific plot, meaning “those who wait.” They were expelled from the land by gunmen, who shot one of them.
A federal prosecutor visited the camp back then, and wrote in a report, “Children, youths, adults and the elderly are subjected to degrading conditions against human dignity. The situation experienced by them is analogous to a refugee camp. They are like foreigners in their own country.”
Four years later, nothing has changed in Tekoha Apika’y. The Indians continue living squeezed between the road and a sugarcane field, which is part of the land they claim. Divided into eight huts, they do not have access to drinking water and depend on meagre donations of food.
Their children show obvious signs of malnutrition. They live with the constant danger of the trucks rumbling closely by them, loaded with Brazil’s rich agricultural commodities, some of which were harvested from plantations on the very land they are claiming as belonging to their ancestors.
I made two trips here, one in early August when Amnesty International’s Secretary General Salil Shetty visited. While I was photographing I heard him say, “I feel like I’m in a place where human rights don’t exist. This is really shameful for Brazil.”
Two weeks after that visit, a fire ravaged the camp, and I quickly returned. Three of the eight shacks were destroyed, and the Indians escaped just in time while their few belongings and food reserves burned. When I arrived I found the community desolate.
“The fire came to kill us, but we survived. Gunmen want to kill us, but we’re not leaving,” sighed Chief Damiana as soon as she recognised me. Her strength is amazing. Even after so many personal losses, she remains decided.
“The seed of my ancestors is in this earth and I will not give it back,” she said.
The cause of the fire remains unknown but Damiana told me how, the night after, gunmen invaded the shacks and threatened to kill the Indians if they didn’t abandon the site. The federal prosecutor opened an investigation into the threats and the possible connection with a major security company already accused of working as a private army for large landholders against other Indian communities.
I went in search of Sandriely, the girl born on the roadside, and found her crying, still frightened, amid the ashes. Her eyes, glistening with tears, contrasted with the grey destruction all around, and I couldn’t avoid thinking of my own daughter Ana, about the same age. Sandriely stuck two sooty fingers inside her mouth while crying. “She’s hungry,” her grandmother said.
“We’re taking back our land with our own blood,” said Getulio Potyvera, a Guarani Kaiowa chief who has received death threats. I met him in his home in the nearby city of Dourados at the beginning of August, as part of my first trip.
He invited me to into his ogapeysu’y, a thatch-roofed house of prayer. As he told it, there is a price on his head. His relatives told the public prosecutor’s office that they were confronted several times by men who were looking for Getulio, offering money for information on his whereabouts.
On the same trip I toured other Tekohas, including one near Caarapo where Indians are fighting to regain Tekoha Pindo Roky. Native women pay a daily tribute at the grave of Denilson Barbosa, shot dead at the young age of 15 by rancher Orlandino Carneiro, last February.
Carneiro confessed to the shooting and was arrested, but is now free on a plea of self-defence. Barbosa’s family is being kept under a government program to protect witnesses and victims of crimes.
The main victims in the land war are the Guarani, with a population of around 50,000 divided among the Kaiowa, Nandeva, and Ava sub-groups. Confined to small areas of land or camped on roadsides, these Indians suffer a long, bitter struggle to return to their traditional territories.
In the past year, Brazil has witnessed a more than twofold increase in violence against native peoples, according to a report by CIMI (Missionary Council for Indigenous Peoples), linked to the Catholic Church. Just in Mato Grosso do Sul, 317 Indians were murdered in the past 10 years. The report also reveals that there were more than 200 attempted murders against Indians in the state during the same period, and, according to the Health Ministry, 470 Indians committed suicide.
Survival International calls the Guarani suicide rate an “epidemic”, quoting Guarani tribe members as blaming it on the loss of land and freedom, and nostalgia for their vanishing way of life.
Last October a group of 170 Guarani Kaiowas wrote an open letter that was interpreted by the media as a threat of collective suicide. In the letter they said they would die together before being evicted from the Tekoha that they were fighting to keep.
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NEW BEDFORD — The defensive strategy worked for a half for GNB Voc-Tech, but host New Bedford found the key and unlocked a 3-0 non-league victory Wednesday night at Walsh Field.
It was the 10th straight victory for the Whalers over their cross-town rivals in their annual game.
Tiago Dourado scored his first of two goals at the 20:16 mark of the second half and New Bedford dominated from there to the finish.
"It was a tough game," GNB Voc-Tech coach Henry Andrade said. "We did a nice job until the first goal was scored, and our energy level went down a little and they capitalized on it.
"I'm happy with the effort my kids put out. Our defensive mode worked in the first half until the first goal."
Dourado's ninth and 10th goals of the season exemplified his game.
"You've got to believe in yourself," Dourado said. "I'm always there for a rebound. I never give up and I was hungry."
The first goal came on a rebound of a shot by Josh Chao.
"Our game is to put the ball on target and have people follow it," New Bedford coach John Macaroco said. "Tiago has a nose to go to the goal. He scores World Cup class goals and he also scores from being in the right place at the right time."
Dourado's second goal came on a charge up the middle at the 29-minute mark.
"I used my speed and blasted it," he said.
The intercity rivalry is tiled heavily in favor of the Whalers and has meaning for the players as well as the coaches.
"This game is always important for the kids," Andrade pointed out.
"It's a derby (cross-town rivalry) to me," Dourado said. "I have a lot of friends on Voc, but we've always been the best team in the city. I've never lost to Voc and I couldn't in my senior year. That would be embarrassing."
The third goal was scored by Chao on a penalty kick. Gilmer Ramos took a header pass into the box and Voc-Tech's sophomore keeper Luis Carranza came out to cut down the angle and reach for the ball. Defender Kyle Shindel got caught in the collision between Ramos and Carranza and touched the ball with his hand.
Chao shot into the right side of the net with eight minutes to play.
New Bedford keeper Eli Reis wasn't challenged much during the contest and recorded his eighth shutout this season.
"When we decide to play our game, it's hard for teams to create good scoring opportunities," Macaroco said. "Our defense is pretty good.
"Tonight, we were patient with the ball and, in the second half, we went wider and opened up the pace of the game. Not many teams can run with us for 80 minutes so, sooner or later, they will break down and that's what happened tonight."
The Whalers (11-1-2, 2-0 Big Three) have lost two regular-season matches in the four years that this senior class has played, including two undefeated seasons. This year, New Bedford lost to Madison Park High of Boston and tied Somerset and Agawam.
GNB Voc-Tech has been very good, too, with its 10-3-2 mark, 10-1-2 in the South Coast Conference. Its other losses were to Bourne and Taunton, and the Bears have tied Apponequet and Bourne.
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We are just past the International Women’s Day 2024 and had a peek at the ephemeral pink Cherry Blossoms of Japan
The people of Panaji are still smarting under the developmental works of Smart City that have made the capital of Goa look like a minescape more than a landscape
and one of the things that makes it ‘golden’ is the Peltophorum ferrugenium
a name that reminds us of the road named after the revolution of 18 June and where the Directorate of Education and the centre for postgraduate studies used to be
The directorate has since moved to Porvorim and the CPIR has been merged with Goa University at Taleigao Plateau but the golden flower trees are still on 18 June road
The rusty shield-bearer or Copper Pod tree is Peltophorum ferrugenium (syn Peltophorum pterocarpum)
The word ‘ferrugenium’ literally means ‘producing iron’ and is a reference to the rusty brown new shoots that are different from the green shoots of the Gulmohar. The one or two-seeded
produce golden flowers for most part of the year
The ground below the tree has a carpet of golden flowers that are a sight to see from end February till the May
Flowers or Gulmohar makes their appearance to paint the town red
The Imagine Panjim Special Purpose Development Limited (IPSPDL) has recently formed a committee to coordinate tree planting in Panaji city in consultation with the Corporation of the City of Panaji (CCP)
An extensive tree survey of trees in the city of Panaji was conducted throughout May and June
and reconciled by another survey in May and June
The then commissioner of CCP is now the chairman of the IPSPDL
The importance of tree architecture for a balanced canopy
especially in stormy weather needs to be understood while pruning trees
2021 by the cyclone Tauktae that knocked down trees across Panaji
My visit to Japan exposed me to the very scientific pruning that their municipal councils execute for the roadside trees
Chain-saws are used in Goa but the tree architecture is rarely considered
The focus only on removal of obstructing branches often results in tree fall during monsoons
It is time to have a closer look at the pruning of trees
The 18th June Road has 49 Copper Pods that have paved the street in gold as in Dick Whittington’s story
only eight of the 73 trees on Atmaram Borkar Road are Copper Pods
There are 49 such trees on Dayanand Bandodkar road; six Copper Pods among the 43 trees on Swami Vivekanand road and 43 Copper Pods at Jogger’s park
one needs to be under a Copper Pod tree this season
we need to add a planned avenue of this golden flowered tree in Patto Plaza to reduce the heat and dust on its streets.