inicia sessão ou cria uma Conta SL Benfica Criar conta › Bruno Jesus and Luciano Maia will be the assistants and Bruno Costa the fourth official The video referee (VAR) will be Tiago Martins Under-19s | Images from the national title win Estoril-Benfica: extended highlights (1-2) The celebration of the five-time champions at Benfica Campus OneFootball's home page Search Settings Sign In Sign InJoinJoao Pinheiro to referee UEFA Champions League clash between Manchester City and Red Star Belgrade | OneFootballCity Xtra João Pinheiro will take charge of the Champions League group stage clash between Manchester City and Red Star Belgrade at the Etihad Stadium in midweek Manchester City begin the defence of their European title at the Etihad Stadium on Tuesday hosting Red Star Belgrade in the opening Champions League Group G clash Pep Guardiola’s side have never previously faced the Serbian club who were also grouped alongside RB Leipzig and Young Boys in the Sky Blues’ Champions League group for the 2023/24 season Manchester City were unbeaten in Europe last season; successfully overcoming Bayern Munich Real Madrid and Inter Milan en route to a maiden Champions League title in Istanbul The Blues are currently unbeaten this season as well including Saturday’s trip to West Ham at the London Stadium Ahead of Tuesday’s clash at the Etihad Stadium UEFA have announced the Match Officials for Manchester City’s meeting with Red Star Belgrade João Pinheiro has been named as the referee for Manchester City’s match against Red Star Belgrade on Tuesday evening who has officiated six matches so far this season took charge of 35 games last year – showing 167 yellow cards and six red cards Pinheiro has never previously refereed a match involving Manchester City but has acted as a VAR and Fourth Official for matches against Borussia Mönchengladbach and Atalanta Pinheiro will be accompanied at the Etihad Stadium by Assistant Referees Bruno Jesus and Luciano Maia Overviewing proceedings will be Video Assistant Referee Tiago Martins and Assistant Video Assistant Referee Pol van Boekel Cláudio Filipe Ruivo Pereira has been named as the Fourth Official The referee will be overseeing conduct within the two dugouts and the behaviour of managers Pep Guardiola and Barak Bakhar Related News“We have to sit down” – Pep Guardiola provides honest reflection on Manchester City’s 2024/25 season What winning the FA Youth Cup meant to City's previous victors Football Association announce FA Cup Final details following Doctor Who and Eurovision clash How Manchester City forward pair helped Liverpool’s Premier League title triumph Manchester City officials chartered aircraft to sign Chelsea forward as a teenager Premier League Awards: Enciso stunner, Semenyo or Delap? Trent Alexander-Arnold announces Liverpool exit Trent Alexander-Arnold has confirmed that he will leave Liverpool this summer via a lengthy social media statement.The academy product is out of contract at Anfield at the end of the... Ruben Amorim worried about Man Utd's 'real dilemma' after record-extending loss OPC UA has been implemented and proven in use at scale on Johan Sverdrup is massive – it produces 30 % of Norway’s total production with OPC UA being a central part of the digitalization strategy since 2015 “The idea behind this platform is to move from silos of data and across our value chain to one common platform that orchestrates all our data across the value chain.” “data without any context is quite useless You need context to ensure that humans and machines understand what the data means in order to be able to use it which can be used for analysis and visualization.” He goes on to explain how Equinor’s business decisions are made faster and better based on the insights derived from the contextualized and/or analyzed data All of this forms Equinor’s four pillars to achieving Data-driven Operations: 1) Data OPC UA is a connectivity framework for industrial automation data managed by the OPC Foundation It systematically supports the contextualization of data available from Equinor’s industrial automation and control systems When viewing the architecture of the heterogeneous OT world and the connectivity to the information the physical equipment is connected to real-time controllers which sends data to the core process control and HMI system The data is tunneled to an IT/OT Gateway to be sent out to Process Historians (IMS) sent to an IMS Historian Cloud Exporter (figure 2) the data goes through a message broker or Cloud Gateway for storage in the OMNIA Data Lake The data is also made available in the OMNIA Timeseries Database so that if a data-consumer (Supplier etc.) requests access to particular data within OMNIA a ticket is created wherein the OMNIA team prepares a Timeseries API to satisfy the request Notwithstanding the connectivity framework that has been built data without context is nonetheless useless and timestamp; but humans and software cannot know if the data is re-lated to a pump a valve; or whether the data point is related to hydrocarbons additional context is needed to make the sensor data actionable In facilities which utilize heterogeneous automation and control hardware and software – which describes almost every process or factory scenario – if each vendor is delivering the same type of data in different vendor- and system-specific interfaces with vendor- and system-specific information models and semantics then humans have to spend a lot of time interpreting incongruent data by mapping and transforming the data It has the ability to turn data into information – data in context – with the OPC UA information modelling framework Its ability to standardize on information across vendors and products contextualized data (information) available this means that two of our four pillars for becoming data-driven are already established it is important that we have our vendors implementing OPC UA so we can lift the data from our [field] level into OMNIA in a much easier and faster way.” Interoperability means that similar information is organized and defined in a standardized way regardless of vendor or system – agreeing on common and open formats while having well-defined and understood interfaces need to agree on standard information models for given domains and assets.” The Enterprise Model OPC UA Library contains all of the templates of all the objects and classes that are defined in all of the different equipment that Equinor has throughout their operations The Engineering Database has within it all of the equipment tag names when merging the OPC UA Library – which is a template that can be used with ANY project – with the Engineering Database the result is a plant-specific OPC UA Mapper; meaning that Equinor has combined all of the types and all of the objects from the library thus automatically assigning types to all the equipment There is no manual intervention – it is an automatic process All that’s left to do is to assign the classes which provides the attributes to be shown on the upper levels of the architecture Each of the field sensors are providing OPC UA data and are connected to the Aggregating Servers (e.g. IACS Gateway or DIG Servers) where the data is replicated to the OT/IT Gateway Once combining the data available from the Aggregating Servers with the plant-specific structure then the information model becomes fully populated the information model is sent to OPC UA Data Collectors and Data Archives Data is made available from the WEB Access Application to anyone with a phone he Equinor OPC UA Template Library consists of 50 objects with the same library being used across multiple assets including renewable energy projects – it’s not strictly an oil and gas library.Equinor’s visualization consists of 745+ pictures that are connected to the available data The tag server started with 190,000+ tags The Equinor OPC UA Asset Structure has defined over 31,000 pieces of equipment – these are the equipment to which earlier reference was made when speaking of automatic “Type” assignment These comprise over one million “Items” and “References” Notwithstanding a wide array of end user benefits which are related to a reduction in the total cost of ownership there are efficiencies gained in the exchange of data without needing human translation in the middle There’s an increase in the flexibility of the overall architecture with easier replacement of components (plug & produce) since the interfaces and information are the same across vendors OPC UA is designed for use across industries making it seamless for a supplier to utilize the same interface and the same information model for myriad customers across various industrial sectors opportunities and in keeping with Equinor’s goal to be a data-driven operator it’s easier and cheaper to access higher-quality contextualized data from plant operations and the industrial automation and control systems Equinor sees improved access to innovation due to broader communities there will be greater competition since owner/operators need to compete on business value and not vendor lock-in Equinor utilizes and benefits from the OPC technology community and by open-sourcing Equinor’s information models The information library is hosted on GitHub It is available to the global community for open utilization at no charge Equinor believes that being open is the key to adoption and that openness is the spirit of OPC UA Equinor is advocating scaling-up broader usage and standardization of OPC UA Information Models There is huge potential for vendors to expand their offerings of OPC technologies there is a strong thirst for tighter integration between the plant floor and cloud applications/services making data and its context available from OPC UA servers there is a gap that can be closed between engineering and operations by aligning AutomationML and OPC UA Equinor envisions benefits through alignment of international initiatives especially since each of them point to OPC UA as one of several key building blocks it would be Equinor’s wish to have the end user community unified as “one voice” while addressing suppliers with industry requirements pertaining to OPC UA technologies READ MONOGRAPH Sara de Almeida Barroso and João Pinheiro da Silva on the purchase from BBVA of the former Castil cinema and was currently occupied by a BBVA.  The team from CMS Portugal advising on this deal was formed by partners pictured right) and João Pinheiro da Silva (Real Estate TELLES hires new co-head of EU and competition law… It represents the main source of information in the legal business sector in Spain and Portugal The digital magazine – and its portal – address to the protagonists of law firms and in-house lawyers The magazine is available for free on the website and on Google Play and App Store information about deals and their advisors For further information, please visit the Group’s website www.lcpublishinggroup.com More than 100 on pitch after Pepe incident sparks brawl AdvertisementHow was your experience today UEFA has appointed officials for the Europa Conference League qualification play-off round second leg between Besiktas JK and FC Dynamo Kyiv Fourth official – Cláudio Filipe Ruivo Pereira The game will take place on August 31 in Istanbul Ptoto – Associação de Futebol de Braga Bruno Jesus and Luciano Maia will be the assistants and Hélder Carvalho the fourth official. The video referee (VAR) will be Tiago Martins, and the assistant (AVAR) Hugo Ribeiro. The celebration of the five-time champions at Benfica Campus! On Friday, January 14, join us on the second episode of Building From Ground Up- season 2. On this episode Koromone Koroye – Managing Editor at TechCabal will be speaking with Vivian Nwakah and João Pinheiro, Co-founders of Medsaf about how to keep your startup afloat with little or no funding. Vivian is the CEO of Medsaf, an online pharmacy that provides both individuals and healthcare facilities such as pharmacies and hospitals, easy, cost-effective medications through its technology platform. She is a serial entrepreneur and strategist that has created and innovated around execution in the healthcare, pharmaceutical, and energy space. João is the CTO of Medsaf. He is a qualified senior developer and has not only shown his programming skills, but also his ability to lead his potential CTO skills with reputable companies in Nigeria and Portugal. On this episode, they will not only discuss what it takes to build and grow a successful startup with limited funding, but we’ll also learn the story of how Medsaf grew from its first funding and how they are transforming access to healthcare in developing markets. Volume 9 - 2023 | https://doi.org/10.3389/fmech.2023.1232562 This article is part of the Research TopicDirect Digital Manufacturing with Process-Structure-Property (P-S-P) RelationshipView all articles Direct digital manufacturing has been identified as one of the key tools of Industry 4.0 and it enables the creation of products directly through digital definition it comprises a set of technologies that are expressively agile in small-scale productions and prototyping in comparison to conventional mass manufacturing processes allows the production of highly complex objects and has been broadly applied in several fields from medical devices to the aerospace industry Although a new era of design possibilities and accessibility was unveiled most developments are focused on shape reproduction precision and the development of new feeding systems and materials This work is focused on a shift in design for additive manufacturing by means of the adjustment of the process conditions (extrusion rate In order to evaluate the morphology of semicrystalline polymers during extrusion-based 3D printing in-situ time-resolving small and wide-angle X-ray scattering measurements were performed at the ALBA synchrotron light source in Barcelona (Spain) The goal of this research is to develop a material property mapping methodology during semicrystalline polymer melt extrusion-based 3D printing Some experiments were performed with low-density polyethylene and we were able to confirm a correlation between the extrusion rate and writing speed of the printing with the level of preferred orientation of the chain folded lamellar crystals in the extrudate In comparison to conventional manufacturing technologies, DDM has enabled a more agile exploration of complex designs, and prototyping has become much faster and less expensive. Moreover, it has been established in industrial and commercial low-volume productions, and for customized tools (e.g., jigs, fixtures) (Paritala et al., 2017) It is assumed that scientists and engineers have another set of technical solutions when designing for manufacturing especially while working on complex and optimized geometries The advantage of mass customization is also beneficial for biomedical applications, where doctors and engineers combine strategies to create custom-fitting products for patients, such as in regenerative medicine, cancer therapies, and drug delivery systems (Morouço et al., 2015) there is not a focus on the material design itself Small-angle X-ray scattering (SAXS) addresses the length of 10–50 nm is able to provide quantitative detail on the size of the chain folded lamellar and the nature of the preferred orientation of these lamellar Time-resolving SAXS is able to follow in real time the transformation of a polymer melt into a semicrystalline morphology and will reveal details of this transformation process which will not be possible to determine from scattering data on the final products at room temperature Wide-angle X-ray scattering (WAXS) is used to determine the crystal structure and the fractions of differing phases present at any specific time Analysis of the WAXS in conjunction with SAXS will determine the shape of the chain-folded lamellar crystals in terms of any twisting during growth Fused granular fabrication (FGF) (or fused particle fabrication) (Woern et al., 2018) is an extrusion-based process that uses plastic pellets instead of a filament as the feedstock it is a suitable approach for the production of bigger parts and for the exploitation of the materials available on the market (typically deployed in injection molding) or custom composites the use of pellets is very straightforward and associated extrusion systems permit a relatively constant extrusion rate (with an even flow of homogeneous melt and without material feed blockages) Representation of the types of fused granular fabrication extruders (A) extruder chamber directly fed with pellets; (B) pellets placed and melt in the piston/plunger chamber; (C) pellets placed and melt in the reservoir material feeding can occur in two ways: directly loading the extruder with pellets or loading it with the polymer melt the beads enter the extrusion chamber (by gravity which has to be cooled to allow the transportation of the plastic material to the heated part where it is compressed and melt Configuration b) requires a full retraction of the piston to allow the refill of the chamber the pellets are then compressed and melted in the same extruder part the material is placed and heated in a separate reservoir The transport of the polymer melt is done by means of the movement of a piston Notice that this configuration has three main heating zones: feeder despite guaranteeing a uniform flow rate of material to a list of parameters commonly involved in this form of additive manufacturing oThermal conductivity and Heat dissipation of the extruder’s body oMechanical elements and movement precision oWrite/print and extrusion speed function (Geng et al., 2019) oAdhesion to bed/platform or to the previously deposited layers of material oPlatform material and finishing (for adhesion and/or heat conduction) ⁃ Viscosity and melt flow index (MFI) oTemperature differential between the layers oTemperature of bed/platform or previously deposited layers of material oAmbient temperature (air and radiant temperatures in closed and open environments) oHeat and matter transfer (air draughts and convection influence) Exploring materials limits in 3D printing requires a set of instruments in order to monitor and contour the above-listed variables (the levels of the list express the dependencies of each main parameter) The time response of the input parameters differs between them and for an “on demand” and “on the fly” control it is rather convenient to have a practically instantaneous transition of the real value to the successive setpoints the property mapping depends on the time it takes for the parameter shifts to have an effect on the material morphology and the amount of time for relaxation and/or crystallization The importance of these factors lies in the resultant precision and resolution of the induced property texture into the object’s material a shift in extrusion rate or print speed happens substantially quicker than with the extrusion temperature Not only this last variable has a noticeable delay associated but it also has a more unstable behavior with successive heating and cooling switches around the target value within a certain interval (overshooting and undershooting) Although an effective extrusion temperature control could be employed this paper focuses on the changes in the writing and extrusion speeds there are limitations such as the overall maximum velocity of the process and the movement precision or induced vibration the low melting temperature (typically from 105°C to 110°C) and the availability of great quantities at a small cost turn the possibility of exploring a vast source of recycled raw material into an opportunity increasing the value of extrusion-based 3D printing and the material itself The exploration of material reinforcement is very significant when including recycled LDPE in the value chain since it has the potential of diluting the effects of degradation (from contaminants and broken molecular chains) induced by the recycling procedures These additives work as nucleation agents which promote faster nucleation and a higher level of crystallinity our ultimate goal is to reinforce the material by mapping its own properties during 3D printing as a consequence of actively changing the process parameters This paper describes the first of many studies to achieve that objective Crystallization processes, whether in a melt or in a solution, involve the processes of untangling the chains and then straightening them to add to the crystal growth face, although the precise details remain unclear. In 1957, a number of researchers deduced that the polymer chains folded at the top and bottom surfaces of the crystals which take the form of thin platelets about 10 nm in thickness but up to several micrometers in the lateral directions (Keller, 1957) Further work revealed that the chain folded lamellar crystals could develop in the framework of a spherulite in which crystals grew out from a common point in a crystallographic direction lying in the plane of the lamellae (Bassett et al., 1986). Figure 2 Schematic representation of a spherulite (semicrystalline structure) Spherulites have been widely studied in polymer science, and the relationships of spherulite morphology to mechanical and other properties have been extensively explored. For instance, it was shown in early studies that the number and size of spherulites are directly correlated with the yield point and overall physical behavior of polymers (Starkweather and Brooks, 1959; Pavlov, 1971) Some efforts to better understand the local mechanical properties have been deployed for mapping along the spherulite radius (Enrique-Jimenez et al., 2016), and to manipulate these structures during the process, with the application of new conditions such as nucleation agents and external loads, obtaining a better orientation of the lamellae and overall elongation (Huan et al., 2013) Other arrangements are possible to observe when the lamellar crystals grow out from a common row nucleus, resulting in a higher level of anisotropy. Not surprisingly these different types of spatial arrangements exhibit different properties both with regard to mechanical behavior and degradation in the case of biodegradable polymers used in biomedical applications (Shah and Vasava, 2019) The formation of row nuclei can be associated with the development of extended chain conformations due to strain in a flow system (Phillips, 1990). Equally highly anisotropic nanoparticles, such as carbon nanotubes (Li et al., 2009) or self-assembling fibrillar nanoparticulate nucleating agents (Shazleen et al., 2021) can lead to higher anisotropic arrangements and a higher level of crystallinity this happens as a consequence of the common alignment of the nucleation sites assuming that the common orientation of the particles introduced during the flow persists at the time crystallization is initiated The same mechanism can occur with the longest molecular chains in a polymer melt. This flow-induced orientation is often associated with the formation of shish-kebab semicrystalline structures (Keller, 1970; Phillips, 1990) (represented in Figure 3) FIGURE 3. Schematic representation of the formation of a shish kebab semicrystalline structure. Adapted from (Dargazany et al., 2014) Basically, the longest chains (with higher molecular weight) become elongated due to the stresses in the flow. If, when reaching the crystallization temperature, these chains remain elongated, they template the nucleation (acting as row nuclei) for the surrounding polymer melt and chain folded lamellar crystals to grow out from. These lamellar crystals have their growth direction normal to the nuclei formed from the elongated chains (Somani et al., 2005) In extrusion-based 3D printing, independently of the plastic part design, the polymer in the liquid phase is forced to pass through a restricting die (nozzle) with a certain length-to-diameter ratio (L/D). Even considering that the extrudate swells at the exit of the extruder (Wang and de Vicente, 2012), the resultant strand diameter is mainly defined by the nozzle diameter, and consequently, it defines the printing resolution, as observed in Figure 4 Representation of the polymer morphology overall change during FGF 3D printing respectively correspond to the melt in the reservoir and the deposited extrudate along the print Shear stresses are applied in order to force the melt to pass through a constricted zone. For semicrystalline polymers (as it is illustrated in Figure 4), this condition induces the elongation of the larger chains (Rubinstein and Colby, 2003), which can generate flow-induced oriented structures such as the shish-kebab arrangements presented in Figure 3 this results in a higher proportion of crystalline to amorphous material These higher levels of preferred molecular alignment are expected to be translated into having a significant impact on the mechanical properties of the manufactured part 3D printed objects can be mapped to be much stiffer in the longitudinal axis of the extruded strands contrasting with a typical isotropic structure regularly obtained the samples correspond to the in-situ produced extrudates of semicrystalline thermoplastic the trials were performed with low-density polyethylene (LDPE) from Repsol with a melt flow index of 7.5 g/10 min For the realization of the morphology analysis, the X-ray scattering was performed with synchrotron radiation, similarly to what has been performed by Mitchell, et al. (Pople et al., 1996); utilizing an especially developed apparatus, in this case, to replicate the extrusion-based 3D printer operation at the beamline. The facilities and the equipment are followingly described in Section 2.2.1; Section 2.2.2 Small and wide-angle X-ray scattering measurements were performed at the ALBA Synchrotron Light Source in Barcelona (Spain), using the NCD-SWEET Beamline (González et al., 2018) This beamline has equipment for the capture of SAXS and WAXS patterns simultaneously The SAXS patterns were obtained in a Q-range from 0.002 Å−1 to 0.125 Å−1 and the WAXS patterns from 1.0 Å−1 to 3 Å−1 The SAXS Detector is a Pilatus3 S 1M system from DECTRIS The X-ray photon absorption in the detector leads to the formation of electron-hole pairs and a charge proportional to the photon energy The Pilatus system is constituted by an arranged set of silicon sensors approximately ∼7% of the detector is intrinsically inactive (this unutilized zone appears as a black stripes grid in the intensity recordings) it is detected and processed by the pixel readout system and the effective pixel has a dynamic range of 20 bits and a size of 172 × 172 μm2 In order to prevent the saturation and damage of the detector a beam stop is placed in front of the detector to absorb the zero-angle transmitted beam The sample to SAXS detector distance was 7.27 m with an incident X-ray wavelength of 1 Å The detector orientation and sample-to-detector distance were calibrated using the well-known standard silver behenate Where n = 0,2,4,6,8 … Only the even orders are required due to the intrinsic inversion centre present in the diffraction pattern of a weakly absorbing material The n = 0 is the component which represents the scattering from an equivalent sample without any preferred orientation n = 2 is the first anisotropic pattern and values of <P2n > correspond to the Herman’s orientation parameter in a scattering pattern from a sample with a high level of preferred orientation are required to fully described the scattering and the orientation distribution function these spherical harmonics are orthogonal functions and a knowledge of one does not depend on the knowledge of the others For samples with a lower level of preferred orientation only components up to n = 8 will be required This equation describes the orientation distribution function of the normal vectors to the lamellar crystals (Q) The first component < P2n> is defined as the orientation parameter on a scale from 0 to 1 the level of anisotropy of the polymer morphology: if < P2n>=0 then the morphology is isotropic; if < P2n>=1 then the crystals share the same alignment FIGURE 5. (Left) A CAD representation of the 3D printer developed for this work. (Right) A schematic of the quasi-static state of the extrudate in a constant gradient of temperature (from the extrusion of the LDPE, passing through crystallization, until cooling down to the surrounding temperature). The evolution of structure can be evaluated by moving the incident X-ray beam down the jet. Adapted from da Silva et al. (2023) this equipment simulates extrusion-based 3D printing along a moving platform with a theoretically infinite path in a single deposition direction (for a wider testing window) This system is adjustable in the cartesian axis and uses a single extruder with a dual channel screw to push the polymer melt through a needle with a high length-to-diameter ratio (L/D ≈ 36) The FGF extruder utilized has a similar design to the one used in the bioextruder (Almeida et al., 2010) (also developed by a team of CDRSP-Polytechnic of Leiria), and it corresponds to the configuration c) in Figure 1 it contains an attached material reservoir and three independent zones of temperature control The communication with a microcontroller board enables the remote operation of the apparatus more specifically the control of the collector velocity (write/print speed) extruder screw rotation velocity (extrusion rate) Figure 6 is a representation of the experimental assembly with the 3D printer mounted on the beamline platform together with the SAXS and WAXS detectors to the scales of observation: lamellae morphology (∼100 Å) and crystalline structures (∼10 Å) FIGURE 6. Representation of the 3D printer analogous equipment mounted on the NCD-SWEET beamline at the ALBA Synchrotron Light Source, with the domain of pattern observation of each detector. Adapted from da Silva et al. (2022) Besides the schematic of the small and wide-angle detectors arrangement this representation shows the main dimensions related to the beamline facilities and the 3D printer For the vertical adjustment of the area to be scanned the distance between the needle outlet and the collector is variable by 50 mm The distance from the sample to the SAXS detector (given by a) was 7.274 m Photograph of the equipment on the mounting stage of the beamline The evaluation of the LDPE crystallization was performed using differential scanning calorimetry (DSC) with a PerkinElmer STA 6000 thermal analyzer. Samples were heated from 30°C to 150°C at a rate of 10°C/min. A steady state at the maximum temperature was maintained for 5 min, followed by cooling back to 30°C at a rate of 5°C/min. The final cooling stage is represented in Figure 8 DSC cooling scan of a sample of LDPE used in this work from 150°C to room temperature (around 30°C) showing the crystallization peak which reveals the maximum rate for a quiescent melt at 90.2°C it is observed that in the quiescent material the onset of crystallization occurs at 94.2°C while the maximum rate of crystallization is observed to be at a temperature of 90.2°C Notice that the material which has been extruded may start to crystallize at a higher temperature than the observed with the quiescent material due to the presence of flow-induced row nuclei In this section, the results of the in-situ small and wide X-ray scattering analysis are presented. Figures 9A–C shows the recorded SAXS scattering patterns of the filaments extruded with different write speeds (print speeds) maintaining the extrusion temperature and rate FIGURE 9. SAXS patterns from the last point of each scan down the extruded filament, at a temperature of 170°C, and a constant extrusion rate with different write/print speeds [increasing from (A–C)]. Adapted from da Silva et al. (2023) These SAXS patterns correspond to the point just before the build platform and are typical for a semicrystalline polymer. Figure 9A shows a practically isotropic ring, indicating an isotropic distribution of the lamellar crystals. On the other hand, Figure 9C exhibits a highly anisotropic distribution of scattering suggesting a higher degree of order of lamellar crystals. Figure 9B corresponds to an intermediate write speed and it comprises both isotropic and highly anisotropic scatterings The WAXS pattern presented in Figure 10 was recorded in the same instant as Figure 9C SAXS pattern corresponding to the arcs observed from right to left the development of an anisotropic morphology is indicated by the variation of the peaks’ intensity in the azimuthal range FIGURE 10. WAXS pattern recorded at the same time as the SAXS pattern shown in Figure 9C. The scattering angle increases from left to right. Only the lower half of the angular range is shown in this figure, corresponding to a Q range of 1 to 2 Å−1. Adapted from da Silva et al. (2023) It is noticed that the anisotropy revealed in the WAXS pattern is less pronounced than the one observed with SAXS This observation underlines the challenge of using wide-angle X-ray scattering to assess the orientation of structures in semicrystalline polymers the twisted arrangement of chain-folded lamellar crystals is commonly observed the preferred orientation of the lamellar crystals cannot be evaluated simply from WAXS patterns The preferred level of orientation of the lamellar crystals, the results are shown in Figure 11. The vertical axis corresponds to the orientation parameter < P2n>, obtained through Eq. 1 this parameter can assume values from 0 to 1 respectively corresponding to a scale from completely isotropic to anisotropic morphology (uniform orientation of the crystalline structures) Plots of the level of preferred orientation of the chain folded lamellar crystals in extruded strands of low-density polyethylene (LDPE) as a function of the collector velocity/print speed (on the left) and the extrusion velocity (on the right) the temperatures of the 3 main zones of the extruder (feeder and extruder body) remained constant (extrusion temperature of 190°C) The left-hand plot corresponds to the variation of the preferred orientation level with the collector velocity (maintaining the extrusion rate value) The plot at the right corresponds to the variation of <P2n> with the extrusion rate (at constant values of collector velocity) Notice that printing speed is represented by the collector main roll rotation velocity given by the product of its angular velocity and radius In order to display any correlations between the preferred molecular orientation and extrusion and collector velocities, the three-dimensional plot shown Figure 12 was prepared, with the combined data from both plots in Figure 11 FIGURE 12. Three-dimensional plot of the level of preferred orientation of the normals to the chain folded lamellar crystals in extruded strands of low-density polyethylene (LDPE) as a function of the extrusion velocity and the write speed (collector velocity) at a constant extrusion temperature, obtained using the data in Figure 11. Adapted from da Silva et al. (2023) it is possible to observe the final anisotropy level in LDPE establishing a briefer correlation with both the extrusion and writing/print speeds (this one represented by the collector velocity) The dark blue corresponds to the isotropic zone and the yellow zones correspond to the higher anisotropy levels the level of preferred orientation of the chain folded lamellar crystals is directly proportional to the collector velocity (write/print speed) and inversely proportional to the extrusion rate In practice, during manufacturing, this is represented by a more pronounced anisotropy value (associated with higher elastic modulus) (da Silva et al., 2022) is reached while extruding a smaller amount of material along the same or a bigger path This can be translated as a thinning of the deposited filament Particular attention has to be given to the faster cooling rates and the thinning of the extrudate, once it may compromise, in a counter-productive way, the interlayer adhesion, as well as the adhesion between subsequently deposited filaments. Consequently, it may affect the mechanical properties and behavior of the generated part (Geng et al., 2019) This condition has to be considered in advance slicing software provides these correlations in order to accomplish the intended geometries if the design for additive manufacturing strategy incorporates this thinning another solution should be the revision of the number of cycles/scans to fulfill a given length/width it is not clearly proven that faster deposition movements of the extrudate should consist of accelerated production at some other level of process optimization if the achievement of a higher level of anisotropy in semicrystalline polymers can be promptly or fully associated with more agile production cycles The use of higher extrusion speed doesn’t necessarily imply a higher manufacturing pace and may limit the overall rate of production new slicing strategies could be applied in order to optimize the anisotropy and obtain well-defined stiffer and softer zones while maintaining a relatively normal to fast-paced production The main conclusion of the present work is that the adjustment of 3D printing parameters (nozzle temperature extrusion rate and write speed) can be utilized strategically to affect the material morphology and structure along the fabrication of an object Exploring the levels of preferred orientation of the lamellar crystals it is possible to transcribe expected properties correlated with the balance between isotropic and anisotropic distributions higher write speeds lead to faster cooling For the same given temperature differential (from the nozzle to the cooled state of the deposited material) constrained and reoriented in the melt flow don’t have enough time to relax and remain mostly extended during crystallization the conception phase of a product can employ this morphology mapping strategy in order to set different mechanical properties it should be expected the possibility to alter conditions and process parameters “on demand” to obtain desirable properties in particular zones of a single material manufactured part This work is dedicated to promoting that approach that the predetermined set of values should be maintained during the whole 3D printing production and depending on the parameter to change (monitoring and control main variable) its set value is theoretically met within a certain period How short or long that response turns out to be in conjunction with the required time for those changes to have an effect on the material morphology controlling the core parameters of 3D printing induces changes in the material structure and morphology of semicrystalline polymers like LDPE it is predicted that will affect the functionality of the printed part allowing the enhancement of mechanical properties in a localized way more than reproducing a certain desired shape it is believed that 3D printing may help develop new degrees of function for even more complex parts The results obtained in this work will be typical for all semicrystalline polymers but the particular details of the correlations will depend on the polymer type the molecular weight and characteristics of the 3D printing systems used including the temperature of the extrusion and the L/D ratio of the extrusion die future works include studies about the rheological behavior and the influence of other variables such as the extrudate temperature the main challenge will consist of the implementation of the correlated data into a manufacturing system where the properties of the materials will be locally assigned along with the digital definition of the objects to produce the active control of the manufacturing process envisioning the optimization of the parts will depend on the implementation of new strategies of slicing and the development of software to run the 3D printing process in accordance with the material design strategies The datasets presented in this study can be found in online repositories. The names of the repository/repositories and accession number(s) can be found below: https://www.cells.es/en/users/call-information-1/bases/2017_07_data_policy_alba_approved-cr.pdf DS; writing—original draft preparation All authors contributed to the article and approved the submitted version This work is supported by the Fundação para a Ciência e Tecnologia (FCT) through the Project references: MIT-EXPL/TDI/0044/2021 UID/Multi/04044/2013; PAMI-Roteiro/0328/2013 (No Add.Additive—Add additive manufacturing to Portuguese industry PO-CI-01-0247-FEDER-024533 and UC4EP PTDC/CTM-POL/7133/2014) These experiments were performed at NCD-SWEET beamline at ALBA Synchrotron with the collaboration of ALBA staff We thank Miguel Belbut from CDRSP-IPLeiria for his help with the evaluation of the orientation parameter The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest All claims 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Silva, Pinheiro, Abdulghani, Kamma-Lorger, Martínez, Solano, Mateus, Pascoal-Faria and Mitchell. 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Volume 15 - 2021 | https://doi.org/10.3389/fncel.2021.637548 This article is part of the Research TopicMolecular Mechanisms Underlying C9orf72 NeurodegenerationView all 8 articles The most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) is a hexanucleotide expansion in the chromosome 9 open reading frame 72 gene (C9ORF72) This hexanucleotide expansion consists of GGGGCC (G4C2) repeats that have been implicated to lead to three main modes of disease pathology: loss of function of the C9ORF72 protein and the production of dipeptide repeat proteins (DPRs) through repeat-associated non-AUG (RAN) translation Five different DPRs are currently known to be formed: glycine–alanine (GA) and glycine–arginine (GR) from the sense strand and proline–arginine (PR) from the antisense strand and glycine–proline (GP) from both strands The exact contribution of each DPR to disease pathology is currently under intense scrutiny and is still poorly understood recent advances in both neuropathological and cellular studies have provided us with clues enabling us to better understand the effect of individual DPRs on disease pathogenesis we compile the current knowledge of specific DPR involvement on disease development and highlight recent advances such as the impact of arginine-rich DPRs on nucleolar protein quality control the correlation of poly-GR with neurodegeneration and the possible involvement of chimeric DPR species we discuss recent findings regarding the mechanisms of RAN translation C9ORF72 repeat associated disease mechanisms The G4C2 repeat expansion can cause C9ORF72 ALS/FTD through three proposed mechanisms (B) RNA foci formation resulting in sequestration of different RNA binding proteins (C) Accumulation of dipeptide repeat proteins (DPRs) generated through RAN translation The third mechanism is a GOF due to the formation and accumulation of DPRs via repeat-associated non-AUG (RAN) translation of the hexanucleotide repeat sequences from both sense and antisense strands (reviewed by Freibaum and Taylor, 2017) (elaborated in this review) The involvement of both LOF and GOF in C9ORF72 ALS/FTD pathophysiology has been comprehensively investigated using different model systems Although more than one of these mechanisms may contribute to C9ORF72 ALS/FTD pathology the presence of DPRs in neurons implies that they likely play a crucial role in disease progression the precise involvement of each DPR species in C9ORF72 ALS/FTD pathogenesis remains unresolved further complicated by a recent finding implicating chimeric DPRs (cDPRs) in C9ORF72 ALS/FTD pathology This review compiles the current knowledge about different DPRs and the recently identified cDPRs and discusses their relative contribution to C9ORF72 ALS/FTD pathogenesis despite being the most readily detected DPR in inclusions it is not clear whether poly-GA is toxic at physiologically relevant levels This delocalization could not be observed with NPM1 and its physiological binding partners capable of inducing the LLPS of NPM1 As NPM1 is heavily involved in ribosome biogenesis and transport hence interfering with NPM1’s ability to fulfill its physiological functions could significantly contribute to DPR-mediated toxicity and most recently disruption of the nucleolar protein quality machinery through the interaction with NPM1 more evidence is required to determine the exact roles the arginine-containing DPRs poly-GR and poly-PR play in the development of the ALS phenotype in vivo Summarizing the detection of DPRs in different human brain regions according to various neuropathological studies examining postmortem brain tissue which suggests that DPR-related toxicity may be responsible for the early progression of the disease The exact role DPRs play in shaping the course of events leading to neurodegeneration thus remains elusive and cannot be satisfyingly answered by solely analyzing postmortem tissue from C9ORF72 ALS/FTD patients Proposed mechanism for the formation of different dipeptide repeat proteins (DPRs) through the G4C2 repeat expansion in the C9ORF72 gene Both sense and antisense strands can be translated through CUG-initiated and RAN mediated translation resulting in the formation of different DPRs cDPRs are proposed to occur because of ribosomal frameshifting or spontaneous mutations in the G4C2 repeat expansion X denotes aminoacids present in N- or C- terminus of DPRs suggesting that poly-GP produced from either the sense or the antisense strand could have different biochemical properties and interacting partners DPRs (and G4C2 RNA) can not only induce the formation of stress granules but also enhance RAN translation and thus their own production resulting in a feed-forward mechanism mediated by the phosphorylation of eIF2α simultaneous inhibition of global protein synthesis might indeed also apply to proteins involved in the degradation of DPRs it is yet to be fully explored how exactly phosphorylation of eIF2α affects the alternative translation initiation mechanisms that are proposed to enhance RAN translation and which form of stress and kinases involved have the most profound effect on RAN translation it remains undetermined by which mechanism the PKR pathway can independently induce RAN translation and to what extent metformin and other PKR inhibitors would be viable therapeutic options for patients with C9ORF72 ALS/FTD More extensive studies will be needed to determine how effective both inhibiting DPR-induced stress and/or targeting different genes important for RAN translation with ASOs will be which potential side effects these treatment options may have other therapeutic targets might revolve around the mitigation of DPR load by directly targeting the individual species of the exact nature and effects of these individual DPR species is highly dynamic as researchers try to unravel the novel mechanisms by which they induce toxicity Although it is accepted that specific DPR species have toxic effects in cellular and animal models their precise contribution to C9ORF72-associated disease progression is still disputed C9ORF72 ALS/FTD patients are likely to express all DPRs and not only a single specific DPR it is essential to understand how individual DPRs may interact with each other at physiologically relevant levels to promote disease pathology this is currently an underexplored area of the C9ORF72-associated ALS/FTD field it still needs to be unequivocally proven that indeed cDPR species are translated in C9ORF72 ALS/FTD patients and then further determined to what extent these species may contribute to the total disease burden evidence suggests that individual DPRs interact with each other and that this may affect disease pathology future work should also consider both C and N-terminus amino acids to more accurately portray the role of each DPR in C9ORF72 ALS/FTD pathogenesis to better understand how DPRs contribute to disease future research should focus on disease models that express multiple DPRs ideally at physiologically relevant levels the development of such models still requires further advances in our current understanding of RAN translation to estimate the precise translated levels of different DPRs in patients This work was supported by the Swiss Foundation for Research on Muscle Diseases Swiss National Science Foundation and the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (Grant agreement No Aladesuyi Arogundade Antisense RNA foci are associated with nucleoli and TDP-43 mislocalization in C9orf72-ALS/FTD: a quantitative study Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons neuronal cytoplasmic and intranuclear inclusions in the cerebellum and hippocampus define the pathology of C9orf72-linked FTLD and MND/ALS Dipeptide repeat proteins inhibit homology-directed DNA double 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Poly(GR) impairs protein translation and stress granule dynamics in C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress Phosphorylation of eIF2 directs ATF5 translational control in response to diverse stress conditions Reduced C9ORF72 function exacerbates gain of toxicity from ALS/FTD-causing repeat expansion in C9orf72 Non-ATG-initiated translation directed by microsatellite expansions Metformin inhibits RAN translation through PKR pathway and mitigates disease in C9orf72 ALS/FTD mice RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia Maharjan N and Saxena S (2021) Emerging Perspectives on Dipeptide Repeat Proteins in C9ORF72 ALS/FTD Copyright © 2021 Schmitz, Pinheiro Marques, Oertig, Maharjan and Saxena. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) *Correspondence: Niran Maharjan, bmlyYW4ubWFoYXJqYW5AZGJtci51bmliZS5jaA==; Smita Saxena, c21pdGEuc2F4ZW5hQGRibXIudW5pYmUuY2g= †These authors have contributed equally to this work Bruno Jesus and Luciano Maia will be the assistants and Miguel Fonseca the fourth official Bruno Jesus and Luciano Maia will be the assistants and Fábio Veríssimo the 4th official. The VAR will be Tiago Martins, and the AVAR Pedro Martins. The 2016 Tulare Holy Ghost Celebration will continue today with a novena and recitation of the Rosary at 7 p.m. in the Chapel at the TDES Hall in Tulare. On Friday, a bloodless bullfight is scheduled at 7 p.m. at the TDES Hall grounds. Featured bullfighters are Joe Correia, Jorge Hernandez and Manuel Telles Bastos. Tickets are $20. The Rosary will be recited daily at 7 p.m. until Saturday, when the crowning of this year’s celebration queen will take place. After the Rosary, there will be a dance and Cantoria, featuring singers Joao Pinheiro, Joao Rodrigues, Manuel do Santos, Adelino Toledo, Jose Esteves, and guitar players Helder Esteves, Michael Vieira, Rafael Ormonde and Joao Gravito. On Sunday, the festivities begin at 10:45 a.m. with a procession from the hall to St. Aloysius Catholic Church, 125 E. Pleasant Ave., for 11:45 a.m. Mass. The first serving of sopas will be at 11 a.m., with an auction to follow at 1 p.m. and a second sopas serving at 7 p.m. Sunday’s festivities continue with a performance from Folklore Group of Tulare at 7:30 p.m. and a grand march at 8:30 p.m. with a dance featuring DJ Tony Nunes. On Monday, there’s vacada at 7 p.m. at the Hall grounds with a dance to follow featuring DJ Dennis Rebelo. The year’s celebration queen is Madison Esteves, 14, daughter of Michael and Gina Esteves. She’s a freshman at El Diamante High School in Visalia. Her attendants are Mikayla Esteves, 15, daughter of David and Diane Esteves and a sophomore at Redwood High School; and Chastine Gist, 14, daughter of Marrs and Cindy Gist and an eighth grade student at Sundale School. The Junior Queen is Caitlin Mendes, 10, daughter of Joe and Monica Mendes and a fourth grade student at Central Valley Christian. Her attendants are Summer Parreira, 9, and daughter of Michael and Danielle Parreira and a third grade student at Mission Valley School; and Bella Valadao, 10, daughter of Eddie and April Valadao and a fourth grade student at St. Rose McCarthy Catholic School. The celebration’s officers are Rosemary and Brian Caso, president; Armando and Jacqueline Da Silva, vice president; Darren and Bethany Rebelo, treasurer; and Mark and Sandra Nunes, secretary. Champions League highlights: Aston Villa 2-0 Bologna Aston Villa's magical Champions League journey continued as they marked Unai Emery's second anniversary in charge by going top of the league phase on another European night to remember set his side on their way against Bologna straight from a free-kick at a raucous Villa Park McGinn's 55th-minute set-piece from out wide evaded everyone inside the penalty area - including Bologna goalkeeper Lukasz Skorupski - before landing in the back of the net The Italians were upset with Portuguese referee Joao Pinheiro as they believed they should have been awarded a free-kick moments earlier Villa doubled their lead nine minutes later when Jhon Duran marked his first Villa Park start for 11 months by sweeping home from close range It was his last touch as he was replaced by Ollie Watkins who was waiting to come on when the Colombia forward scored with Duran showing his displeasure at being replaced by kicking the back of a seat in the dugout Having beaten Swiss side Young Boys and heavyweights Bayern Munich earlier this season Villa now have nine points from three games as Emery's side continue to make light work of their return to European football's top club competition Unai Emery says Aston Villa deserved their 2-0 win over Bologna Duran 'on fire' but under Emery's 'control' Have your say on Aston Villa's performance This was another night to remember for Villa fans under Emery as their team go from strength to strength under the Spaniard When Villa announced the Spaniard's appointment on 24 October 2022 following the sacking of Steven Gerrard they were struggling at the wrong end of the Premier League table Fast forward 24 months and Villa are enjoying their best start to a Premier League season in 26 years while sweeping all before them in Europe Villa did not have it all their own way against Bologna When Sam Beukema headed against the woodwork in the closing stages Emery was seen having strong words with his set-piece coach Austin MacPhee With nine points in the bag and five games still to go - Club Brugge (away) Villa can start thinking about the knockout stage They need another two wins to reach 15 points, which the Opta supercomputer, external believes is required to secure a top-eight finish and automatic passage to the last-16 Villa carved out 16 attempts against Bologna as they responded to the outstanding atmosphere whipped up by the home fans Villa Park was a cauldron of noise by kick-off with fireworks - as well as an eye-catching tifo featuring three lions - greeting the players when they stepped on to the pitch Home fans belted out the Champions League anthem before their team brushed aside Bologna While Villa are yet to concede in the competition There was applause from all four sides of the pitch when Samuel Iling-Junior came on for the Serie A club in the 77th minute - the 21-year-old winger's first appearance at Villa Park Watch highlights of every Champions League game from 22:00 BST on Wednesday on BBC iPlayer and the BBC Sport website and app There will also be a Champions League Match of the Day on BBC One on Wednesday After the opportunity to rate players has closed the score displayed represents the average from all the submissions by BBC Sport users To load Comments you need to enable JavaScript in your browser The BBC is not responsible for any changes that may be made Ravaglia Match OfficialsReferee: João PinheiroVideo Assistant Referee: Tiago Bruno Lopes MartinsAssistant Referee 1: Bruno Miguel Alves JesusAssistant Referee 2: Luciano MaiaFourth Official: João António Ferreira GonçalvesAssistant VAR Official: Fedayi SanMatch StatsKey Skip back to form guideSkip back to season so farMatch FactsScroll LeftScroll RightAston Villa and Bologna have never faced in any competition The Villans have lost four of their six major European games against Italian sides with the two wins both coming at home against Internazionale in October 1990 and September 1994 After winning their first three games against English opponents in major European competition Bologna have lost their last two such games both away against Leeds United in the Inter-Cities Fairs Cup in April 1967 and to Liverpool in this season’s UEFA Champions League Aston Villa have won both of their games in the UEFA Champions League this season – 3-0 v Young Boys and 1-0 v Bayern Munich they’ll equal their longest streak of victories in the European Cup/Champions League last stringing together three consecutive wins in September-October 1981 Aston Villa could become only the third side to win their opening three games in the UEFA Champions League without conceding after Málaga in 2012-13 and Leicester City in 2016-17 Bologna are winless in their last four games in major European competition (D2 L2) and could become the first side to fail to score in their first three games in the UEFA Champions League since FK Austria Wien in 2013-14 (a run of four) Victory for Aston Villa will see Unai Emery pick up his 25th win in the UEFA Champions League becoming the fifth Spanish manager to achieve as many wins in the competition after Pep Guardiola Only Feyenoord (606) have applied more pressures in the opposition’s half in the UEFA Champions League this season than Bologna (572) with 353 of them coming in the final third only Manchester City (395) and Atlético Madrid (358) having more in 2024-25 Only Bremer and Kamil Piatkowski (both 5) have played more line-breaking passes breaking two or more lines among central defenders in the UEFA Champions League this season than Aston Villa’s Pau Torres (4) it was a line-breaking pass that provided the assist for Jhon Durán’s winner against Bayern Munich last time out Aston Villa’s Morgan Rogers has completed more dribbles than any other player in the UEFA Champions League this season (9) with five of those coming against Bayern Munich last time out Only Barcelona’s Iñigo Martínez (20) has completed more progressive carries over 10 metres in the UEFA Champions League this season than Bologna’s Dan Ndoye (19) Jacob Ramsey (Aston Villa) right footed shot from the centre of the box is saved in the centre of the goal Fourth official has announced 3 minutes of added time Charalampos Lykogiannis (Bologna) wins a free kick in the defensive half Sam Beukema (Bologna) hits the left post with a header from the left side of the six yard box Assisted by Charalampos Lykogiannis with a cross following a corner Jens Odgaard (Bologna) left footed shot from outside the box is blocked Santiago Castro (Bologna) wins a free kick in the attacking half Morgan Rogers (Aston Villa) left footed shot from the left side of the box is blocked Jacob Ramsey (Aston Villa) wins a free kick in the defensive half Giovanni Fabbian (Bologna) wins a free kick in the defensive half Charalampos Lykogiannis (Bologna) left footed shot from outside the box misses to the right Benfica increased their advantage at the top of the Primeria Liga to six points after beating Porto 1-0 at Estádio do Dragão The Dragons were dominant early on before Stephen Eustáquio was sent off in the 27th minute Sérgio Conceição’s side were unable to recover fortunate to go into the break level after Fredrik Aursnes and Rafa hit the woodwork Roger Schmidt’s side remained patient however knowing a chance would come which they took in the 72nd minute Rafa raced clear and combined with David Neres the playmaker finding the bottom corner in the decisive moment of the match PortuGOAL's Matthew Marshall reports from the Dragão Porto piled on the pressure in the opening stages Fábio Cardoso unable to keep his shot down after receiving Odysseas Vlachodimos’ weak punch inside the 18-yard box João Mário and Alexander Bah were both booked for taking down Galeno whose pace was causing the Eagles a lot of problems in transition The Dragons created a fantastic chance in the 15th minute Zaidu Sanusi’s cross picked out Mehdi Taremi his header towards the top corner denied by Vlachodimos who made a sensational save Enzo Fernández tried his luck from distance with Benfica unable to test Diogo Costa João Mário and Fredrik Aursnes’ lack of speed resulting in Gonçalo Ramos frequently getting dragged out wide to get on the ball Stephen Eustáquio was booked for a tackle on Alexander Bah in the 24th minute before Bah got forward and headed Fernández’s cross narrowly wide The turning point in the match came in the 27th minute when Porto were reduced to 10 men Eustáquio showed his inexperience with another late challenge on Bah with referee João Pinheiro producing a deserved second yellow card Sérgio Conceição resisted the chance to make a change Mehdi Taremi spending most of his time on the right wing and Otávio moving into central midfield Benfica went desperately close to taking the lead in the 37th minute Fredrik Aursnes surging past him and hitting the post the ball rebounding off Diogo Costa straight into the path of Rafa who headed off the bar when it looked easier to score Fernández was the next player booked after taking down Pepê Aursnes getting his name in the book on the stroke of half time Roger Schmidt was clearly concerned about his booked players suffering the same fate as Eustáquio the tactician making a triple substitution at the break with Gilberto Julian Draxler and David Neres replacing Bah Rafa’s shot deflected wide in the 60th minute before Draxler picked up an injury and was replaced by Petar Musa Sérgio Conceição made his first change in the 67th minute when Gabriel Veron replaced Evanilson the game opening up which was always going to be hazardous for the depleted hosts. And so it proved with Benfica scoring the decisive goal in the 72nd minute Pepê got caught out of position once again the Eagles racing clear through Rafa and David Neres who exchanged passes Rafa turning on the penalty spot and finding the bottom corner Conceição reacted by bringing on Wendell and Toni Martínez for Zaidu Sanusi and Galeno Martinez headed Pepê’s cross straight at Vlachodimos and Otávio saw his shot blocked Conceição’s last throw of the dice bringing his son Rodrigo onto the pitch in the 89th minute as Porto’s fake supporters abandoned their team Benfica were looking more likely to add to their lead in added time when Costa clawed a David Carmo clearance off the line Veron had a half chance in the final minute his deflected shot comfortably saved by Vlachodimos With Sporting Clube de Portugal well off the pace and Braga’s early season promise unsustainable matches between Porto and Benfica were always going to receive extra attention Porto had gone undefeated in their last nine games against Benfica which included seven wins and two draws the Eagles’ last win against the Dragons coming in March 2019 Few teams leave Estádio do Dragão with three points in this case they are extra valuable with Schmidt’s side going six points clear at the top of the Primeira Liga It wasn’t a great spectacle but Roger Schmidt and his side won’t care one bit Porto started strong in front of their supporters but it was always going to be an uphill battle after Eustáquio’s dismissal Wilson Manafá lacking match fitness and Rodrigo Conceição on the bench we saw Pepê Aquino get another start in an unfamiliar position The Brazilian was nowhere to be seen when Aursnes and Rafa hit the woodwork in the first half and he was similarly absent when Benfica scored his defensive duties left to Taremi on both occasions Why Sérgio Conceição waited until the 67th minute to make his first substitution is curious but probably another examlpe why he is a level below the elite managers in club football There is no need to dissect this game any further Conceição was sent off after the final whistle answered one question in the post match press conference before storming out telling you all you need to know about what he thought of the game Benfica now unbeaten in 19 matches this season They had a favourable draw against average opposition which they capitalised on and carried into the Champions League where they beat Juventus in Italy and earned two draws against PSG The Clássico in Porto was another stern test that Roger Schmidt’s side passed with assistance from Stephen Eustáquio Schmidt has kept the momentum going despite missing three injured central defenders He handed António Silva his debut at Boavista the 18-year-old starting all 12 games since Avoiding defeat against Juventus on Tuesday will see Benfica qualify for the Champions League knockout rounds with one match remaining It would be another fantastic achievement in a season that keeps on giving for Eagles supporters The game from matchday 28 of the Liga NOS takes place at Estádio da Luz at 7:15 pm on Tuesday Bruno Rodrigues and Nuno Manso will be the assistantsand Sérgio Guelho will be the fourth official The VAR will be Rui Costa and the AVAR Tiago Costa The referee of the encounter will have Bruno Rodrigues and Nuno Eiras as assistants and Dinis Gorjão as the fourth official The video-referee (VAR) will be Luís Ferreira and the assistant (AVAR) Paulo Miranda The referee of the encounter will have Bruno Rodrigues and Nuno Eiras as assistants and Vítor Ferreira in the role of the fourth official The video referee (VAR) will be António Nobre and the assistant (AVAR) Paulo Brás Statistics from the Liga NOS: x-ray of the Tondela-Benfica match 🎥 Chiquinho: return with great passing accuracy 🎥 Bruno Lage: “Tivemos uma mentalidade competitiva e vencedora” Ferro’s header in Bruno Lage’s winning record Tiago Costa and Pedro Ribeiro will be the assistants and Iancu Vasilica the fourth official Bruno Rodrigues and Nuno Eiras are the assistants and Pedro Ferreira the fourth official The VAR will be Bruno Paixão and the AVAR António Godinho Tiago Costa and Luciano Maia will be the assistants and Ricardo Baixinho the fourth official Nuno Eiras and Sérgio Jesus will be the assistants and Iancu Vasilica the fourth official The VAR will be António Nobre and the assistant (AVAR) André Campos Zivkovic: "Our team is to be congratulated" Rui Vitória: “Giving up does not enter our vocabulary” The referee of the encounter will have Bruno Rodrigues and Nuno Eiras as assistants and André Narciso in the role of fourth official The video-referee (VAR) will be Jorge Sousa and the assistant (AVAR) Sérgio Jesus Nélson Veríssimo: "We will be a team looking for the goals and the victory" Nossos serviços estão apresentando instabilidade no momento Algumas informações podem não estar disponíveis 2022 10h00 AM | Last Updated: September 30 Value of forestry production hit a reacord R$30.1 billion with an increase of 27.1% and production in 4,884 municipalities Value of silviculture production is still above that of wild crop harvesting Silviculture has been on an upward trend since 2020 (an increase of 21.3% from 2019) Wild crop harvesting advanced 31.5% and reached R$6.2 billion a value of production Data come from the survey of Forestry Activities (PEVS) 2021 “Forestry products increased significantly in value in 2021 That has to do with the rise of the dollar and to the resumption of industrial production The most significant increase was that of value of forestry production (27.1%) Most of that (79.3%) comes from silviculture whereas wild crop harvesting accounts for 20.7%,” says Carlos Alfredo Guedes manager at the IBGE’s Agriculture department He explains that silviculture’s participation in value of production of the sector increases every year That does not mean wild crop harvesting has been reduced but that silviculture products have a higher value silviculture even fell by 0.7% in terms of value of production whereas in wild crop harvesting there was an increase leading it to 20.7% of the total value,” Mr areas with planted areas in the country dropped 1.4% The total silviculture area amounts to 9.5 million hectares eucalyptus and pine tree were responsible for coverage of 96.0% of the areas with planted areas for commercial purposes in the country The Southeast was the only Major Region with increase in planted area of silviculture with an increase of 30.7 thousand hectares (0.9%) which has 31.9% of the areas planted with pine tree and eucalyptus in the country According to data from the Secretariat of Foreign Trade (SECEX) pulp was in the ninth position in the ranking of total exports in the country in 2021 (2.4%) The participation of wood products remains preponderant in the sector with 95.6% of the values of forestry production Value of production of wood products from planted areas increased by 23.7% whereas wild crop harvesting recorded an increase of 37.9% “These results confirm the trend to increase of wood products from silviculture and show a bigger increase of these products in 2021,” Mr Value of production increased in all the groups Value of production of wood for production of pulp and paper increased by 24.4%; of charcoal Despite the drop throughout the time series wild crop harvesting recorded increase in the value generated in 2019 (6.9%) Whereas wood products account for almost the entire value of silviculture production in terms of wild crop harvesting this group represents 63.5% Minas Gerais has highest value of silviculture production: R$7.2 billion Minas Gerais still keeps the highest value of silviculture production The state is the main producer of charcoal Paraná is in the second position in terms of planted forests It is the biggest producer of logged wood for pulp and paper being responsible for 17.6% of the national production Logged wood for other purposes also stood out which represents 37.0% of the national overall and the state remains as the main producer in the country Minas Gerais still holds the biggest area of planted forests in the country almost all of which covered with eucalyptus São Paulo has the second biggest area of planted forests Among the 10 municipalities with the biggest areas of planted forests in Brazil Four municipalities in Mato Grosso do Sul are on the leading position regarding planted area in Brazil among which Três Lagoas and Ribas do Rio Pardo stand out both have the biggest areas of planted forests with 237.3 thousand hectares and 196.8 thousand hectares João Pinheiro (MG) is the municipality with the biggest planted area in the state with areas divided into eucalyptus and pine trees Paraná leads national production of firewood from silviculture Paraná is the leader in firewood production from planted forests with a production of 11.3 million cubic meters The South Region accounts for 63.3% of the national firewood production João Pinheiro records highest value of silviculture production   João Pinheiro (MG) recorded the highest value of silviculture production in 2021 Telêmaco Borba (PR) followed with R$556.2 million with 73.0 thousand cubic meters and generating R$3.5 million “João Pinheiro (MG) was in the second position and surpassed Telêmaco Borba (PR) in terms of value of production That results from the demand of steel industry for charcoal produced in João Pinheiro stands out due to the production of logged wood for pulp and paper production,” Mr Among the 20 municipalities in the country with highest forestry production figures 16 had a predominance of silviculture and the other four had as a highlight the production of yerba mate Colniza (MT) and Prainha (PA) stood out due to logged wood Wild crop harvesting increases by 31.5% and generates R$6.2 billion in value of production value of production of wild crop harvesting increased 31.5%; it amounted to R$6.2 billion Among the nine groups of products encompassed by forestry oilseeds was the only one recording decrease in value of production (-2.8%) with the biggest participation in value of wild crop harvesting (63.5%) when wood harvesting fell in relevance and reversed the trend of the last few years in which forestry exploration for wood was gradually replaced by production from planted forests many wood products recorded positive changes Logged wood recorded an increase of 46.7% in value of production; firewood Mato Grosso and Pará accounted for 56.3% of the production of logged wood which had surpassed Pará as the main producer in 2020 with value of production of R$ 152.7 million Acai and yerba mate have highest value of production among non-wood products are the products generating the highest production value amount produced and value of production considering the exploration of planted forests (silviculture) and of natural vegetation resources (wild crop harvesting) among which the highlights are: wood products © 2018 IBGE - Instituto Brasileiro de Geografia e Estatística Nós utilizamos cookies para melhorar sua experiência de navegação no portal. Para saber mais sobre como tratamos os dados pessoais, consulte nossa Política de Privacidade. Lindia remembers the volcanic ash raining down Residents of the former whaling village of Capelo in Faial would walk down the streets with open umbrellas trying their best to protect themselves from the darkness that covered the sun their land and their sustenance by the time the yearlong eruption of the Capelinhos volcano subsided and the island grew by a few acres Almost everybody ended up having a better life because of the volcano The Capelinhos volcano gave rise to a third wave of Azorean immigration to the United States thanks to the Azorean Refugee Act of 1958 spearheaded by then-Sens Other Azoreans who took advantage of the special legislation and the softer immigration laws followed suit during the 1960s and 1970s As a popular high school student involved in sailing Pinheiro had dreams of attending college and had no plans to leave the Azores But the volcano ruined the island's mostly agricultural and seafaring economy after ash covered the dock where Azorean whalers made their living "Our immigration was different from the other types of immigration "I ended up staying here and I'm glad that I did," he said The volcano started slowly just off the coast of Capelo but soon erupted in spectacular explosions reaching more than 3,000 feet high the volcano experienced almost all kinds of volcanic behavior forcing residents to sleep out on the streets for days in a row Pinheiro remembers a funny episode when two groups of journalists one from the Azores and one from mainland Portugal raced in small boats to try to be the first to reach a small island the volcano had created "The ones from mainland had a Portuguese flag The island eventually connected to land near the Capelinhos lighthouse before the eruption finally ceased on Oct said he went to see the volcano only once when he lived in Faial He had worked as a clerk in a grocery store in the city of Horta but the eruption presented a chance to leave for America "I wanted to come to America because everybody talked about America," he said and all I did was go to work and come home Those who came to the United States are now marking the life-changing cataclysm with a yearlong series of events throughout the area The events parallel a series of celebrations in the Azores The observances begin tonight with a banquet at the Venus de Milo restaurant in Swansea co-chairwoman of a committee putting the local celebrations together "There's never been something to bring people together so they can share the emotions they felt back then," Mrs Other events include an oral history project two book releases and a contest for local schoolchildren Azorean officials from Faial are expected to visit the area next June for a local event that includes several awards Celebrations will close in September 2008 with another dinner that will include the giving of awards for the school contest the Azores and elsewhere is available at www.vulcaodoscapelinhos.org The Web site includes an English language version as well as many photos and a 23-minute documentary about the volcano That Portuguese-language documentary tells the story of the imposing Capelinhos lighthouse and the yearlong volcanic eruption that destroyed it Read today's Portuguese stories delivered to your email The occupancy rate in local accommodation in the Azores is currently around 85% but could exceed 90% at Easter along with a growth in tourists from Canada “We have good occupancy rates for the Easter period, which starts next week. We are at around 85% occupancy. And we are expecting it to exceed 90% by the end of Easter,” said the president of the Azores Local Accommodation Association (ALA) According to the official, unlike last year, when Easter took place in March, when the IATA summer had not yet started "there are good prospects" for the festive period with Easter coinciding with the IATA summer flights are back to normal and we expect a good season" The president of ALA told Lusa that “national tourists continue to be the best market” during the Easter period with additional demand from the French and German markets admitting that this may be occurring due to the so-called "reciprocal tariffs" imposed by the United States on its trading partners "We have not yet seen a decline in American tourists we are seeing a great demand from tourists coming from Canada," he added Local accommodation represents 62% of the total number of beds in the Azores and the issue of air connections in the low season and the lack of labor continue to be the main concerns of business owners We appreciate that not everyone can afford to pay for our services but if you are able to we ask you to support The Portugal News by making a contribution – no matter how small You can change how much you give or cancel your contributions at any time Send us your comments or opinion on this article Reaching over 400,000 people a week with news about Portugal the Kazakhstan national team played away against Slovenia The game was held at the stadium “Stozice” in Ljubljana The hat-trick was scored by Slovenian forward Benjamin Šeško Kazakhstan will play its next match in the Nations League away against Austria on October 10 The match will take place at the Raiffeisen Arena in Linz Fourth official: João Gonçalves (Portugal) The ad-free version is ready for purchase on iOS mobile app today we couldn't find that page";var n=e.querySelector("h2");return n&&n.remove(),{staticContent:e,title:t}},d=function(e){var t=document.createElement("button");return t.innerText=e,t.classList.add("error-page-button"),t},f=function(e){var t=document.createElement("div");t.id="recirculation-404",t.classList.add("brand-hint-bg");var n="\n \n \n \n \n \n '.concat(e,' Tick here if you would like us to send you the author’s response who has been a diplomat all his professional life and served the interests of Portugal in Latvia and Senegal among other places says that Europeans are now living in a time of fundamental change and unprecedented financial crisis in which their leaders might not know exactly what scenarios the future will present The Portuguese ambassador to Slovakia is optimistic about Europe’s future though he warns that the years ahead will be difficult He says that not even the painful austerity measures that his government has had to take have changed the fact that the Portuguese continue to identify themselves as European citizens The Portuguese ambassador to Slovakia is optimistic about Europe’s future The Slovak Spectator spoke to Ambassador Niza Pinheiro who arrived here in 2010 and sees much potential for building bridges between Portugal and Slovakia links between Portuguese and Slovak academia and businesses and tourism potential between the two countries The Slovak Spectator (TSS): Portugal has some of Europe’s sunniest areas which has understandably resulted in the rapid growth of the use of solar power in Portugal What are the main challenges that Portugal faces in the area of renewable energy?Joao Luís Niza Pinheiro (NP): Renewable energy is something that has been at the centre of our attention especially in the past decade given the fact that Portugal has a quite high – currently around 77 percent – energy dependence on external resources sufficient amounts of coal and nuclear energy has been excluded so it is crucial for us to pursue an adequate energy mix namely balancing it with renewable resources developed in our territory bearing in mind the situation in the world as well environmental considerations we have subscribed to the 20-20-20 targets at attaining 31 percent of the primary energy in that horizon and in energy efficiency reducing our energy consumption by 25 percent by the same time with our public sector setting an example by reaching a reduction of 30 percent but achieving them will reduce Portugal’s energy dependence as well as keeping our country at the forefront of the European Union in the use of renewable energies My Government sees the role of this sector as one of the motors for the competitive advantage of Portugal I would use recent figures released by Eurostat to illustrate that we are on a good track to achieving those targets: the EU average in renewable energy stood at 12.4 percent of total energy consumption in 2010 this should result in lower dependence on oil which is the largest source of energy in Portugal TSS: Slovakia has been trying for the past two decades to forge better links between the needs of the labour market and academia and is now a country with a rich university heritage?NP: Yes Portugal has a rich university heritage which goes back to 1290 when King Denis founded and granted academic autonomy to the University of Coimbra one of the three oldest universities in Europe This autonomy became an essential characteristic of our system Later the University of Évora emerged in the 16th century marking an important landmark in our university system up to the 20th century when the modern University of Lisbon and the University of Porto were established as public institutions In the early 1970s a number of other public and private universities were set up Yet the whole network has shown a paramount interest in research and interaction with Portuguese enterprises The network was completed by polytechnic institutes which further strengthened the links between businesses and academia The direct links between the universities and businesses include research centres as well as conducting applied research through contracts with individual firms Then research teams from the universities participate in so-called ‘collective research projects’ financed by public funds Specialised units known as incubators to promote start-ups for research done in universities are yet another form of link a certain pragmatic philosophy behind these links between academia and businesses these links have not always been this strong and it was the variety and the increasing development in the academia approach and the growing power of the private sector in Portugal alongside with the continuous internationalisation of Portuguese firms which allowed us to fully realise how useful these links can be and how they can work for the benefit of the whole country there is an important number of starting enterprises which come from this connection are directly emerging from these combined forces which puts them in the forefront of innovation and competitiveness in the economy This is actually one of the areas where I see great potential for cooperation between Slovakia and Portugal and we can mutually learn from each other: you live in a different part of Europe and your economy is doing very well and I think together we can explore interesting ways of bringing academia and the private sector together TSS: The financial crisis has seriously impacted your homeland and in 2011 Portugal became the third EU country after Greece and Ireland to ask for a financial bailout your government has already introduced a package of reforms What are its main pillars and how did the population receive them?NP: The global economic crisis in 2008 to 2009 has been underestimated at a global level which is the primary source of our difficulties The assistance programme negotiated with Portugal is a comprehensive and vast one based on three pillars: budget consolidation; reduction of indebtedness of the economy and reinforcement of the stability of the financial system; and structural reforms to create conditions for more competitiveness of the economy and sustainable development Four review joint missions of the European Commission the ECB and the IMF have extensively scrutinised its implementation and all them have concluded that there is compliance with the goals The Government has continuously declared itself fully committed to the targets and most of the Opposition while criticising some of the aspects of the programme thus allowing for a clear and strong supportive majority in Parliament although severely hit by a series of measures is enduring them without public unrest of the type that we have seen for much less reason in the last two years in some other member states In Portugal we witnessed no riots or buildings on fire although there were general strikes and demonstrations – but these did not really require police intervention and meant that the population freely expressed its feelings but they are expected to be more visible during the very next years It would be very time-consuming to go in detail I will just select two of them: we came from a budget deficit of around 9 percent and reduced it which is a huge consolidation; a considerable plan of privatisations is underway and the first ones are done TSS: Have recent problems within the eurozone as well as the related austerity measures affected the public’s attitude towards the European Union Is there any significant growth in euroscepticism in your homeland?NP: In April I read a piece in Financial Times which suggested that despite the sacrifices the mood of the Portuguese towards the European Union is not showing any fundamental change referring to the fact that only 16 to 18 percent of the population opposed the current developments in the EU suggested that 70 percent of the Portuguese feel themselves European citizens and say that Portugal must stay in the eurozone although concerning the specific issue of austerity only 36.5 percent of the population agrees with the measures required by Brussels I think the EU is deeply ingrained in the lifestyle and thinking of the Portuguese people and I do not foresee any dramatic change In fact euroscepticism has no party representation in Portugal TSS: Could you please describe the current state of economic cooperation between Portugal and Slovakia?NP: Our business links are rather recent: Slovakia has been present in Portugal since the country’s accession to the European Union and we have been present in Slovakia since 2005 I am only the second resident ambassador in Slovakia Slovakia is well-positioned as a destination for Portuguese exports of goods and has made it into the 50 top countries Slovakia ranks 40th in the Portuguese imports Over the past five years the trade balance in goods has always been positive for Slovakia while positive for Portugal in the trade balance in services TSS: Do you think that the investment potential between Slovakia and Portugal has been fully explored What are the areas where you see some potential for cooperation between the two countries?NP: Foreign direct investment from Slovakia to Portugal has been very limited and of course we would like to have more investment from Slovakia We follow the same rules and pay with the same currency and have a very similar system of commercial policies Among the limitations is perhaps that both countries are trying to attract direct foreign investment although of course we are focusing on different markets from Slovakia which is why we are organising various business missions some three months ago the Slovak Chamber of Commerce and Industry took a business mission to Portugal where it co-operates with the Portuguese Industrial Association Your automotive sector is interesting since it is a well-developed sector in Portugal too; among others we have Volkswagen So one of the potential areas for increased business could be for sub-suppliers of parts and accessories for vehicles Also in electronic services: when you think about e-government or electronic procurement our firms have solutions that already moved Portugal into the international arena and I see a potential for the two countries to work closer together in these areas there is the area of scientific and technological cooperation since my country has strongly invested in areas such as biomedical sciences communication and information technologies and this has moved us to the European vanguard for example the International Iberian Nanotechnology Laboratory one of the best-equipped institutes in Europe and thus Slovakia could also benefit from such an area of cooperation So there are tools for exchanging researchers some of this cooperation is already happening: we have some 12 projects underway with Slovakia and 53 research projects were financed by the 7th framework programme of the EU was among the fastest growing languages in the United States How do you assess the interest of Slovaks in Portugal the Portuguese language and the culture of your homeland?NP: I was pleasantly surprised after I found out that there is a real interest in Bratislava A course of Portuguese language and Portuguese culture exists since some years at Comenius University A Portuguese lecturer paid by Portugal is directing it and about 50-90 people might be enrolled every year showed an interest in starting Portuguese courses while the training would be directed at more specific economic terminology which named itself the Portuguese Institute and emerged from local people’s need to be in contact with our language TSS: How do you assess the tourism potential between the two countries and what do you think Slovakia has to offer Portuguese tourists?NP: There is potential There is now a daily direct flight from Vienna to Portugal which is convenient since it takes only about three hours to get to Lisbon Of course I would like to see more Slovaks visiting my homeland and probably they are still not completely aware of what we can offer them This is a role mainly for tourism agencies on both sides Since the purchasing power of Slovaks is getting close to the EU average perhaps they will be able to travel more and Portugal will be on their list of countries has excellent hotelier schools and we could cooperate by providing training in them In Slovakia now the golf sector is growing which is very interesting for the Portuguese as we are now one of the top countries in Europe for golf The Portuguese might also be interested in skiing in the High Tatras since you have competitive prices in your skiing stations But without a doubt we do need to increasingly discover each other because more exposure of the peoples to each other through direct visits will also help integration at the European level The requested URL was not found on this server Unai Emery's side have lost just once this term - a 2-0 defeat to Arsenal in the Premier League - and have shown their worth in the Champions League with victories over Young Boys and Bayern Munich The Midlands club are currently sixth in the league phase table and will want to make it a third successive European win on Tuesday Bologna upset the odds to qualify for the Champions League but have endured a tough start to the 2024/25 season Following the departure of former manager Thiago Motta the Serie A side have found victories hard to come by Here is 90min's guide to Aston Villa vs Bologna This is the first competitive fixture between Aston Villa and Bologna Unai Emery has welcomed back some missing players / Crystal Pix/MB Media/GettyImagesJohn McGinn made a welcome return to action off the bench during the weekend's 3-1 win over Fulham with the Scotsman having been sidelined for around a month Boubacar Kamara had been missing since February but the midfielder was named on the bench at Craven Cottage Tyrone Mings has been another long-term absentee but he could feature in Tuesday's squad after over a year out of action back-up goalkeeper Robin Olsen will miss out with a head injury Emery has been reluctant to make too many alterations between Premier League and Champions League games this season meaning he could field a very similar lineup to the one that won in west London at the weekend Aston Villa predicted lineup vs Bologna (4-2-3-1): Martinez; Konsa Samuel Iling-Junior is on loan from Villa / Alessandro Sabattini/GettyImagesBologna have a mountain of injuries heading to Villa Park including Villa loanee Samuel Iling-Junior Martin Erlic and Lewis Ferguson in the treatment room who caused Liverpool problems in Bologna's last European outing missed the weekend's draw with Genoa but could return this Tuesday The same applies to Moroccan defender Oussama El Azzouzi Bologna predicted lineup vs Aston Villa (4-1-4-1): Skorupski; Posch Unai Emery took Aston Villa to the Europa Conference League semi-finals last season / Richard Heathcote/GettyImagesBologna have been draw specialists this season with seven of their nine matches finishing without a winner. However, they have had a pretty favourable run of fixtures at the start of the new campaign against some of Serie A's weaker sides While they showed their teeth against Liverpool in defeat it seems unlikely that the Italian side will be able to better their result at Anfield when they return to England They have scored just nine times in eight Serie A matches and haven't been particularly inspiring at the back Villa find themselves in tremendous form as they continue to juggle European football and the Premier League seamlessly They have been electric in front of goal this term and have earned clean sheets against Bayern Munich and Manchester United in two of their last three fixtures © 2025 Minute Media - All Rights Reserved The content on this site is for entertainment and educational purposes only Betting and gambling content is intended for individuals 21+ and is based on individual commentators' opinions and not that of Minute Media or its affiliates and related brands All picks and predictions are suggestions only and not a guarantee of success or profit If you or someone you know has a gambling problem crisis counseling and referral services can be accessed by calling 1-800-GAMBLER.