Texas Rattlers veteran sits tied with fourth-most conversions amongst premier series pack Texas – If you’d have asked us whether we thought veteran Claudio Montanha Jr would be ranked within the Top 12 of the Unleash The Beast World Championship standings with less than two months remaining until the 2025 PBR World Finals at ANY POINT in the past two years we’d have politely declined the idea.And lost the bet the 35-year-old pieced together a rather productive session for the Texas Rattlers last summer finishing the year 8-for-14 as a depth contributor to the 2023 Champs as he shook off a bit of rust But that was only good enough for a No so the idea that he’d be shifting things into overdrive during the 2025 premier series campaign wasn’t something that seemed likely at the time. Yet it’s the exact circumstance hundreds of thousands of fans around the world continue to witness lately as the Brazilian seems determined to make some noise once more riding a bit of a second wind during what’s become quite the unpredictable season.  Just seven days after tying Paulo Eduardo Rossetto for seventh-place honors back in Milwaukee Montanha went on to secure a third-place finish last weekend in Little Rock courtesy of a flawless performance.One of just four men to stay perfect throughout the three-round showcase he earned his first podium appearance of the season by tying tour leader Brady Fielder for third place. Pairing an 87.5-point journey aboard Hunter from Round 1 with an 85.5-point mark in Round 2 atop Mr he found himself competing in his eighth short round of the season Selecting a rematch opportunity with Hoobastank the very bull which bucked him off during Milwaukee’s Championship Round he made sure to finish the job this time around.  Now 5-for-6 over the course of the circuit’s last two showdowns he’s still 421.5 UTB points behind the Australian who continues to set the pace But the only way to chase him down is consistently turning in quality performances. Bringing six Top 10s and 10 Top-15 efforts into this weekend’s competition it’s fair to say he’s been one of the more consistent guys around this season Having ridden at least one bull in 14 of the 16 events in which he’s competed in he might only be averaging an 84.6-point score when he meets the 8. But if that’s the formula which can keep him within striking range Tied with Keyshawn Whitehorse and Cort McFadden with the fourth-most qualified rides on tour The Brazilian veteran has also attempted the most bulls of all cowboys on the circuit one more than Luciano De Castro and two more than Fielder and Koltin Hevalow. With a pair of premier series victories to his resume dating back to the 2019 and 2021 campaigns he understands what it feels like to win big on the top tour. It’s just been a while.Yet his third and fourth-place efforts this season suggest he could be on the cusp of collecting what would be his first UTB event title in nearly four years. Preparing to challenge his 43rd bull of the season will the trending talent continue his climb up the standings? Be sure to check out all of this weekend’s action LIVE and FREE beginning Friday night The stream for Kubota PBR Louisville begins Friday ET.Fans can keep an eye on PBR.com and @PBR social media channels for the latest news wrecks and more! Photo courtesy of Josh Homer/Bull Stock Media 8 seconds is all it takes to become a legend Read today's Portuguese stories delivered to your email founder and artistic director of MiratecArts and producer of the “Montanha Pico Festival” announced this weekend at the New Bedford Film Festival that the thirteenth edition of the festival which happens on the Azorean island and highest point of Portugal will dedicate a Spotlight in the programming to New Bedford or works by New Bedford filmmakers are welcomed,” divulged Terry Costa after the panel dedicated to South Coast Filmmakers We can have one session with a few shorts or quite an extensive selection of the best works representing the city and what its artists produce.” We appreciate that not everyone can afford to pay for our services but if you are able to we ask you to support The Portugal News by making a contribution – no matter how small You can change how much you give or cancel your contributions at any time Send us your comments or opinion on this article Reaching over 400,000 people a week with news about Portugal The page you are looking for might have been removed Top 30 riders from Round 1 will advance to Wednesday night’s Round 2 – In a field of 90 riders split across two nights of competition for the opening round of the Pendleton Whisky Velocity Tour (PWVT) Denver PBR Chute Out at the National Western Stock Show With the highest ride score of the entire two-day extended round at 91 points the 35-year-old Texas Rattlers athlete dominated his matchup with a previously unridden bull Earning 29 Velocity Global points for his efforts heads into the third day of competition atop the leaderboard.  the Top 30 riders from Round 1 will return to each face one bull The 15 bull riders with the top combined ride scores following the first two rounds will then advance to the final championship round on Wednesday night Texas) secured second place in Round 1 courtesy of his action-packed matchup with Renegade for 87.5 points on Tuesday night In addition to sailing into Wednesday’s final round who is on the Missouri Thunder roster during the PBR Team Series Oklahoma Wildcatters man Cort McFadden (Novice Texas) and seven-time PRCA World Champion Sage Kimzey (Strong City Oklahoma) tied for third place in the round with matching 87-point ride scores.  a member of the Austin Gamblers who won the 2024 Championship title was in control aboard Ringling Road from the moment the chutes flew open Tuesday night McFadden had the Denver Coliseum crowd cheering as he triumphed over Down to Fly.  Kimzey and McFadden each collected 16.5 Velocity Global points for their efforts New York Mavericks’ standout Leonardo Castro (Cassilandia Brazil) rounded out the Top 5 with an 85.5-point ride aboard his bovine opponent Cutting Edges Bandit In addition to punching his ticket to Round 2 the Brazilian cowboy earned 15 Velocity Global points.  The Denver PBR Chute Out will continue at the National Western Stock Show on Wednesday immediately followed by the championship round.  PBR Pendleton Whisky Velocity Tour (PWVT) - Denver PBR Chute Out  National Western Stock Show – Denver Round 1-Round 2-Event Aggregate-Event Points1 US EditionUK EditionScottish SunIrish SunSearchMy Account Senior Boxing ReporterPublished: Invalid Date Butterbean was once beaten in a K1-kickboxing bout against giant fighter Montanha Silva Butterbean - real named Eric Esch - was an icon in combat sports and was primarily known for his career in the traditional boxing ranks where fans became enthralled by his KO power and huge physique Esch took on one of the most formidable challenges of his career when he took on huge standing 6ft 11ins Silva in a kickboxing clash Silva had a whole foot advantage over Esch who stands at 5ft 11ins but it was a challenge he was certainly up for trying to navigate Resembling of 'David vs Goliath' the American faced off with his rival who towered over him as the first bell rang The opening round began with Silva extremely hesitant waiting patiently for the natural boxer to come to him when the pair let their hands go in small flurries The giant went down again as Butterbean charged forward, but it seemed to be ignored as a knockdown despite him collapsing after a shot landed through the guard. A second stanza followed a similar pattern with Esch trying to close the gap, so much so he speared his rival into the ropes and on to the canvas. The final round came and went in a similar vein with many feeling that Esch had actually done enough to get a nod on the judges' scorecards. but looked reluctant and landed less shots was ultimately handed the decision on the judges' scorecards given Esch failed to cause any significant damage Unfortunately it wasn't to be with Silva declared the winner by unanimous decision but fans were simply stunned with Esch's effort overall He had performed well to even try to overcome the size difference which to many was the biggest they had seen in combat sports David Haye and Nikolai Valuev shared a similar height disparity, one which Haye sensationally overcame to become world champion in the boxing cruiserweight division Silva's next moves came in four forthcoming clashes in kickboxing But the Brazilian now works as a Jiu-Jitsu practitioner and wrestler in his home country and has become a phenom due to his frightening size Esch went on to fight in an array of different disciplines after his third consecutive K1 defeat He had already burst on to the scene two years before in a showdown with heavyweight legend Larry Holmes, during which he was battered and unfortunately lost His final outing came in 2013 when he lost his final clash to Kirk Lawton and was forced to turn his back on combat sports given he had health issues Since that day, Esch has lost 200lbs in weight and is a completely transformed man Butterbean has even made surprise calls for a comeback at the age of 58, particularly given Mike Tyson will face Jake Paul in a professional fight this year The American had already called out Paul several years ago and was forced to turn down his own potential exhibition with Tyson to whom he has now made a winner-takes-all offer He has even shown off training footage insisting he hasn't 'lost his power' but a full return currently seems unlikely Get the latest fight news, reaction and the best opinion from talkSPORT pundits in our Boxing WhatsApp channel. 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Volume 13 - 2022 | https://doi.org/10.3389/fphar.2022.814134 This article is part of the Research TopicWomen in Drug Metabolism and Transport: 2021View all 6 articles The aim of the study was to apply Physiologically-Based Pharmacokinetic (PBPK) modelling to predict the effect of liver disease (LD) on the pharmacokinetics (PK) of dexamethasone (DEX) in the treatment of COVID-19 A whole-body PBPK model was created to simulate 100 adult individuals aged 18–60 years hepatic blood flow) and portal vein shunt were incorporated into the LD model The changes were implemented by using the Child-Pugh (CP) classification system DEX was qualified using clinical data in healthy adults for both oral (PO) and intravenous (IV) administrations and similarly propranolol (PRO) and midazolam (MDZ) were qualified with PO and IV clinical data in healthy and LD adults The qualified model was subsequently used to simulate a 6 mg PO and 20 mg IV dose of DEX in patients with varying degrees of LD The PBPK model was successfully qualified across DEX the simulated systemic clearance of DEX decreased (35%–60%) and the plasma concentrations increased (170%–400%) in patients with LD the AUC ratio between healthy/LD individuals remained comparable to lower doses The exposure of DEX in different stages of LD was predicted through PBPK modelling providing a rational framework to predict PK in complex clinical scenarios related to COVID-19 Model simulations suggest dose adjustments of DEX in LD patients are not necessary considering the low dose administered in the COVID-19 protocol different forms of administration and detailed description of the individuals included in the study (e.g. LD severity according to CP score) are lacking The aim of this study was to use PBPK modelling to predict DEX PKs for the treatment of COVID-19 in patients with liver impairment A whole body PBPK model constructed using Simbiology v was used to generate a cohort of 100 individuals aged 18–60 years (50% female and 50% male) The following assumptions were made during simulations: 1) instant and uniform drug distribution (well-stirred model) across each compartment (tissue/organ); 2) no reabsorption of the drug from the colon; and 3) drug distribution was limited by blood flow No ethical approval was required as results for this investigation were generated virtually TABLE 1. Physiological and biochemical parameter changes in the liver disease model according to CP score (A, B, C). Johnson’s reported values (Johnson et al., 2010) Oral absorption was simulated using a compartmental absorption and transit model (Bosgra et al., 2012). The drug absorption rate constant (Ka) was calculated using the effective permeability (Peff) based on the in vivo regional jejunal permeability in humans for PRO (Gertz et al., 2010). For MDZ and DEX values observed in the literature for Ka were applied. The parameters are described in Table 2 Physiochemical and pharmacokinetic characteristics of dexamethasone The clearance of MDZ, PRO and DEX in the gut (CLgut) were calculated considering the intrinsic clearance (Clint) and abundance of the enzyme involved in the metabolism of each drug in the intestinal tissue (Eq. 1): The fraction of drug escaping gut metabolism and transitioning to the liver (Fg) was computed with the following equation (Eq. 2): Where Qgut represents the blood flow to the gut, and fu,gut is the fraction unbound of the drug in the gut, considered equal one in the model. (Yu and Amidon, 1999) Similarly, to the gut, the intrinsic clearance of each enzyme involved in the hepatic metabolism of MDZ, PRO and DEX were scaled up to the whole liver (CLint, liver) considering the equation below (Eq. 3): The MPPGL was calculated according to equation reported by (Eq. 5) Barter et al., 2008: The total hepatic intrinsic clearance (∑CLint, liver) was considered as the sum of all enzymes involved in the metabolism. The hepatic systemic clearance (CLhep) was calculated considering blood flow and the total ∑CLint, liver (Eq. 6): Where Qhv is the hepatic blood flow rate, fup is the fraction of drug unbound in plasma and R is the blood to plasma ratio. The fraction of drug that escapes hepatic metabolism and reaches the systemic circulation (Fh) is represented by the following equation (Eq. 7): Where Qpv is the blood flow rate of the portal vein Given DEX`s auto-induction of CYP3A4, induction of CYP in the intestine and liver were calculated from using the following equation (Eq. 8): Where Emax is the maximum enzyme activity, Corgan,u is the average unbound drug concentration in the intestinal and liver tissues and EC50 is the DEX concentration required to reach half of the maximum enzyme activity. Then the CLgut and CLint, liver (Eq. 1 and Eq. 3) was multiplied by IndCYP3A4,organ Portocaval shunting was incorporated into the LD model by implementing a shunt index that considers the varying levels of shunting associated with the different severities of liver disease as well as the serum total bile acid concentrations in the peripheral vein (Ohkubo et al., 1984; Simón-Talero et al., 2018). The fraction of drug that bypasses the liver due to shunting (Fshunt) is represented by the following (Eq. 9): Elimination of MDZ and PRO were considered as exclusively hepatic however, for DEX an additional renal clearance amounting to 10% of the systemic clearance was applied in accordance with the literature (Table 2). (HEMADY, 2021) A liver impairment scaling factor for renal function was applied as described in Table 1 Overall step-by-step workflow representing the PBPK modelling qualification and predictions The mean PK parameters for PRO across all individuals were also calculated and compared for both simulated and observed clinical data The PBPK model was used to predict the PK of DEX in virtual populations with varying degrees of liver disease, classified according to CP scores (A, B, and C). The varying levels of portacaval-shunting associated with liver disease considered in the simulations was an aleatory linearly spaced range with minimum value of 0.1 and maximum value of 0.7 as previously described (Simón-Talero et al., 2018) The dosages selected for the simulations were in line with current COVID-19 protocols stipulated by the National Institute for Health and Care Excellence; 6 mg dose once a day PO for 7–10 days; 6 mg dose once a day IV for 7–10 days (The National Institute for Health and Care Excellence, 2021) The PK parameters were calculated considering steady-state plasma concentration on 10th day in accordance with the COVID-19 protocol The PBPK model was successfully qualified for all drugs in healthy (MDZ, PRO and DEX) and LD individuals (MDZ and PRO) according to the selected criteria. The simulated and observed PK parameters for each drug as well as the AFE values are presented in Table 3, as previously described. The plasma concentration-time profiles of each drug are described in the supplementary material (Supplementary Figures S1–5) Qualification of the PBPK model in healthy and liver disease individuals for midazolam Predictions of dexamethasone pharmacokinetics in virtual populations with varying degrees of liver disease Simulated concentration-time profile of DEX in different LD conditions after 6 mg intravenous administration (graph on the top) and 6 mg oral administration (graph on the bottom) Dashed lines represent simulations with shunting and solid lines with no shunting The clinical management of individuals with LD is challenging. The PK of DEX in LD patients has been partially described through a clinical study, showing a reduced clearance and increased half-life, but no information of total exposure (AUC0-inf) and PK profiles were available (Kawai et al., 1985) The PBPK model described herein simulated DEX PK in different stages of LD with various grades of shunting providing evidence-based guidance towards the clinical management of COVID-19 in LD patients the AUC ratio between healthy and individuals with LD remained comparable to the lower dose (6 mg once a day) no simulation with shunt effect was performed with the higher dose since the same behaviour of lower dose is expected Whilst side effects need to be monitored during the administration of DEX no dose adjustments seem necessary in healthy or LD patients and unknown LD physiopathology mechanisms not represented in the model corroborate the challenge of qualifying the LD PBPK model against specific CP classifications An increased exposure of DEX across varying stages of LD was predicted using PBPK modelling Although DEX exposure was predicted to be more than 3 times higher in CP-C individuals no dose adjustments seem necessary in patients with LD considering DEX’s low hepatic extraction the low dose administered in the COVID-19 protocol and short period of treatment (10 days) This study provides in silico evidence-based guidance towards the management of complex clinical scenarios related to COVID-19 and provides a rational framework for future PBPK modelling applications in LD patients Further PBPK modelling initiatives would be necessary to evaluate the net effect of both LD and inflammatory physiological alterations on the PK of drugs used in the treatment of COVID-19 - To propose a PBPK model capable of simulating the PK of drugs in LD patients classified according to the Child-Pugh system - To integrate portacaval-shunting associated with LD in a PBPK model - To predict DEX exposure in LD patients considering the dose administered in the COVID-19 protocol The original contributions presented in the study are included in the article/Supplementary Material further inquiries can be directed to the corresponding author All authors contributed to the overall concept of the model and MS wrote the manuscript with support from all the other authors All authors reviewed and contributed to the final manuscript This project is funded by a research grant awarded by the UKRI (MRC) and the DHSC (NIHR) The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher The Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fphar.2022.814134/full#supplementary-material Deciding on success Criteria for Predictability of Pharmacokinetic Parameters from In Vitro Studies: an Analysis Based on In Vivo Observations PubMed Abstract | CrossRef Full Text | Google Scholar Simultaneous Quantification of the Abundance of Several Cytochrome P450 and Uridine 5'-Diphospho-Glucuronosyltransferase Enzymes in Human Liver Microsomes Using Multiplexed Targeted Proteomics PubMed Abstract | CrossRef Full Text | Google Scholar ACTEMRA® (tocilizumab) (2021) Google Scholar A Comparison of Pharmacokinetics between Humans and Monkeys PubMed Abstract | CrossRef Full Text | Google Scholar Covariation of Human Microsomal Protein Per Gram of Liver with Age: Absence of Influence of Operator and Sample Storage May Justify Interlaboratory Data Pooling PubMed Abstract | CrossRef Full Text | Google Scholar Physiological Parameter Values for PBPK Models Google Scholar An Improved Model to Predict Physiologically Based Model Parameters and Their Inter-individual Variability from Anthropometry PubMed Abstract | CrossRef Full Text | Google Scholar Physiological Parameter Values for Physiologically Based Pharmacokinetic Models PubMed Abstract | CrossRef Full Text | Google Scholar The Effect of Age on Plasma Levels of Propranolol and Practolol in Man CrossRef Full Text | Google Scholar Corticosteroid-related central Nervous System Side Effects CrossRef Full Text | Google Scholar de la Grandmaison Organ Weight in 684 Adult Autopsies: New Tables for a Caucasoid Population PubMed Abstract | CrossRef Full Text | Google Scholar Effects of Interleukin-6 (IL-6) and an anti-IL-6 Monoclonal Antibody on Drug-Metabolizing Enzymes in Human Hepatocyte Culture PubMed Abstract | CrossRef Full Text | Google Scholar DrugBank (2021a). Dexamethasone. Available at: https://go.drugbank.com/drugs/DB01234 (Accessed 27 October 2021) Google Scholar DrugBank (2021b). Midazolam. Available at: https://go.drugbank.com/drugs/DB00683 (Accessed 27 October 2021) Google Scholar DrugBank (2021c). Propranolol. Available at: https://go.drugbank.com/drugs/DB00571 (Accessed 27 October 2021) Google Scholar Physiology-based Simulations of a Pathological Condition: Prediction of Pharmacokinetics in Patients with Liver Cirrhosis PubMed Abstract | CrossRef Full Text | Google Scholar EMA. (2021a). Guideline on the Evaluation of the Pharmacokinetics of Medicinal Products in Patients with Impaired Hepatic Function. Available at: https://www.ema.europa.eu/en/evaluation-pharmacokinetics-medicinal-products-patients-impaired-hepatic-function (Accessed 27 October 2021) Google Scholar Google Scholar The Impact of CYP3A5*3 Polymorphism on Sirolimus Pharmacokinetics: Insights from Predictions with a Physiologically-Based Pharmacokinetic Model CrossRef Full Text | Google Scholar FDA (2021). Guidance for Industry: Pharmacokinetics in Patients with Impaired Hepatic Function: Study Design, Data Analysis, and Impact on Dosing and Labelling. Available at: https://www.fda.gov/media/71311/download (Accessed 27 October 2021) Google Scholar Prediction of Human Intestinal First-Pass Metabolism of 25 CYP3A Substrates from In Vitro Clearance and Permeability Data PubMed Abstract | CrossRef Full Text | Google Scholar Physiologically Based Pharmacokinetic Modeling in Regulatory Science: An Update from the U.S Food and Drug Administration's Office of Clinical Pharmacology PubMed Abstract | CrossRef Full Text | Google Scholar HEMADY (dexamethasone Tablets) (2021) A Semi-mechanistic Model to Predict the Effects of Liver Cirrhosis on Drug Clearance PubMed Abstract | CrossRef Full Text | Google Scholar Differences in Metabolic Properties Among Cortisol and Dexamethasone in Liver and Renal Diseases: Accelerated Metabolism of Dexamethasone in Renal Failure CrossRef Full Text | Google Scholar Evaluation of Maternal Drug Exposure Following the Administration of Antenatal Corticosteroids during Late Pregnancy Using Physiologically-Based Pharmacokinetic Modeling PubMed Abstract | CrossRef Full Text | Google Scholar Prevalence of Chronic Liver Disease in Patients with COVID-19 and Their Clinical Outcomes: a Systematic Review and Meta-Analysis PubMed Abstract | CrossRef Full Text | Google Scholar Characterization of CYP2C19 and CYP2C9 from Human Liver: Respective Roles in Microsomal Tolbutamide PubMed Abstract | CrossRef Full Text | Google Scholar Assessment of Drug-Drug Interactions between Voriconazole and Glucocorticoids CrossRef Full Text | Google Scholar Dexamethasone in Hospitalised Patients with COVID-19: Addressing Uncertainties PubMed Abstract | CrossRef Full Text | Google Scholar Role of portal and Splenic Vein Shunts and Impaired Hepatic Extraction in the Elevated Serum Bile Acids in Liver Cirrhosis PubMed Abstract | CrossRef Full Text | Google Scholar Characterization of Interintestinal and Intraintestinal Variations in Human CYP3A-dependent Metabolism Google Scholar The Human Intestinal Cytochrome P450 "pie" PubMed Abstract | CrossRef Full Text | Google Scholar Pentikäinen Pharmacokinetics of Midazolam Following Intravenous and Oral Administration in Patients with Chronic Liver Disease and in Healthy Subjects Google Scholar and Prediction of Osimertinib Drug-Drug Interactions Using PBPK Modeling Approach to Inform Drug Label PubMed Abstract | CrossRef Full Text | Google Scholar Prediction of Pharmacokinetics Prior to In Vivo Studies Mechanism-Based Prediction of Volume of Distribution CrossRef Full Text | Google Scholar and Complications of Related COVID-19 Deceased: a Systematic Review and Meta-Analysis PubMed Abstract | CrossRef Full Text | Google Scholar CrossRef Full Text | Google Scholar Effects of Liver Disease on Pharmacokinetics PubMed Abstract | CrossRef Full Text | Google Scholar Incorporation of the Time-Varying Postprandial Increase in Splanchnic Blood Flow into a PBPK Model to Predict the Effect of Food on the Pharmacokinetics of Orally Administered High-Extraction Drugs PubMed Abstract | CrossRef Full Text | Google Scholar PubMed Abstract | CrossRef Full Text | Google Scholar Impact of Interleukin-6 on Drug-Metabolizing Enzymes and Transporters in Intestinal Cells PubMed Abstract | CrossRef Full Text | Google Scholar Modeling Approach to Predict the Impact of Inflammation on the Pharmacokinetics of CYP2C19 and CYP3A4 Substrates PubMed Abstract | CrossRef Full Text | Google Scholar Simón-Talero Association between Portosystemic Shunts and Increased Complications and Mortality in Patients with Cirrhosis PubMed Abstract | CrossRef Full Text | Google Scholar A Study of the Relationship between Serum Bile Acids and Propranolol Pharmacokinetics and Pharmacodynamics in Patients with Liver Cirrhosis and in Healthy Controls PubMed Abstract | CrossRef Full Text | Google Scholar The National Institute for Health and Care Excellence (NICE) (2021). COVID-19 Rapid Guideline: Managing COVID-19. Available at: https://www.nice.org.uk/guidance/ng191/resources/covid19-rapid-guideline-managing-covid19-pdf-51035553326 (Accessed 27 October 2021) Google Scholar Cytochrome P450-Mediated Metabolism in the Human Gut wall CrossRef Full Text | Google Scholar Population Pharmacokinetic Model Characterizing 24-Hour Variation in the Pharmacokinetics of Oral and Intravenous Midazolam in Healthy Volunteers PubMed Abstract | CrossRef Full Text | Google Scholar The Cytochrome P450 3A4 Inhibitor Itraconazole Markedly Increases the Plasma Concentrations of Dexamethasone and Enhances its Adrenal-Suppressant Effect PubMed Abstract | CrossRef Full Text | Google Scholar Vecchié High-dose Dexamethasone Treatment for COVID-19 Severe Acute Respiratory Distress Syndrome: a Retrospective Study PubMed Abstract | CrossRef Full Text | Google Scholar Concerns about Pharmacokinetic (PK) and Pharmacokinetic-Pharmacodynamic (PK-PD) Studies in the New Therapeutic Area of COVID-19 Infection PubMed Abstract | CrossRef Full Text | Google Scholar Pharmacokinetics and Dosage Adjustment in Patients with Hepatic Dysfunction Eur CrossRef Full Text | Google Scholar An Update on Current Therapeutic Drugs Treating COVID-19 PubMed Abstract | CrossRef Full Text | Google Scholar A Compartmental Absorption and Transit Model for Estimating Oral Drug Absorption CrossRef Full Text | Google Scholar Khoo S and Siccardi M (2022) PBPK Modelling of Dexamethasone in Patients With COVID-19 and Liver Disease Received: 15 November 2021; Accepted: 11 January 2022;Published: 28 January 2022 Copyright © 2022 Montanha, Cottura, Booth, Hodge, Bunglawala, Kinvig, Grañana-Castillo, Lloyd, Khoo and Siccardi. 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Advertise on Cineuropa Logos and Banners CANNES 2024 Directors’ Fortnight by Teresa Vieira 20/05/2024 - CANNES 2024: Paulo Carneiro takes us to Covas do Barroso in Portugal for a truly captivating portrait of the local community’s fight against lithium mining It’s a hybrid movie that portrays the real-life hardships – and These are people who have been fighting against the attempts of British company Savannah Resources to create the biggest European open-pit lithium mine in their midst A duel can be seen as taking place between these two sides – Savannah and the mountain – and the film opts for a fable-like storytelling style mixed with hints of western visual and narrative notes The fictional approaches used in this movie enable it to strike a righteous balance between a light captivating mood and a strong political stance that can easily resonate with the general public A particular part of the allure stems from who we see on screen and even how we see them: people from Covas do Barroso playing a role that is imbued with a slight touch of fantasy as well as a certain theatrical flair as they reenact the events that have unfolded over the past few years As we are led through the different seasons and as the threat of the open-pit mine edges closer and becomes ever more real different forms of movement can be observed: there are calendar-based rituals different processions that keep elements of cultural memory and local history alive There are also the things that people are trying to save the ingredients that make this home for them But then one can also sense the movement of the community itself their unity and strength growing stronger every step of the way We also sense movement through the opportunity to feel and observe different routines and dynamics as if we had been transported into this town’s very way of life motorbikes and trucks are signs that very clearly situate the audience in terms of which side we’re following (be it the heroes or the enemies) these vehicles are portrayed in the context of the vast landscape: with the occasional use of wide shots means of transportation can make their way through the landscape but the director still shows that the scenery All of the songs throughout – composed by Carlos Libo – set a very powerful tone musical elements connected with sounds from the objects in use in agriculture; on the other hand some of the pieces ooze a feeling of collective participation “collective” is one of the key words in this whole experience: we get a sense of being invited not only to listen to and be aware of what all of these voices have to tell us The mesmerising cinematography lures us in: the precise editing leads us through proceedings but it’s the overall positive feeling we get in every scene that will stay with us afterwards It’s this sensation that elevates the film even further sincere and tender homage to the people of Covas do Barroso but also a very promising sign of what the future (of film Savanna and the Mountain is a Bam Bam Cinema (Portugal) production, in co-production with La Pobladora Cine (Uruguay). Its international sales are entrusted to the Portugal Film agency Please subscribe to our newsletter to receive more stories like this directly in your inbox “Since I don't believe in conventional documentary anyway, I started to write the story as a fiction” CANNES 2024: The Portuguese helmer breaks down his aesthetic concept and how he worked with the protagonists of his documentary-fiction hybrid   18/05/2024 Afternoons of Solitude opens the ninth edition of the Spanish film festival this Friday, which is dedicated to auteur and independent cinema   25/02/2025 | Ibiza 2025 Ten projects have been selected for the former strand, while Agora Boost will offer expert guidance to four Greek documentary projects at various stages of development   03/02/2025 | Thessaloniki Documentary 2025 | Agora The French filmmaker is also rewarded for his work as a screenwriter, while the Spanish films They Will Be Dust, The Rim and Salve María also receive awards   28/10/2024 | Seminci 2024 | Awards “We will go from surprise to surprise, from unexpected to unexpected” The general delegate of the Directors’ Fortnight in Cannes discusses the 2024 selection and sheds light on the debate regarding its editorial line   18/04/2024 The Romanian gathering will showcase “the cinema of truth” from 20-27 October, offering four competitive sections and a host of thematic sidebars for all generations   07/10/2024 | Astra 2024 CANNES 2024: Paulo Carneiro takes us to Covas do Barroso in Portugal for a truly captivating portrait of the local community’s fight against lithium mining   20/05/2024 | Cannes 2024 | Directors’ Fortnight 21 feature films, including two animations and two documentaries, grace the agenda of a selection full of surprises, and dominated by Patricia Mazuy, Jonas Trueba and Thierry de Peretti   16/04/2024 | Cannes 2024 | Directors' Fortnight The industry section of the gathering organised a range of activities and showcased new technologies for its over 400 international attendees   10/03/2023 | Thessaloniki Documentary 2023 | Agora/Awards The 11 participating projects from Southeastern Europe and the Mediterranean region will be in with a chance of winning one of the Agora Docs in Progress post-production awards   14/02/2023 | Thessaloniki Documentary 2023 | Agora 02/05/2025goEast 2025 Review: My Magical World 30/04/2025Films / Reviews – Italy Review: San Damiano 30/04/2025Hot Docs 2025 Review: King Matt the First 29/04/2025Films / Reviews – Italy Review: Storia di una notte 29/04/2025Films / Reviews – Peru/Spain Review: Kayara. La guerrera del Imperio Inca 29/04/2025Hot Docs 2025 Review: Supernatural Subscribe to our newsletter to receive the most important daily or weekly news on European cinema Distribution / Releases / Exhibitors Europe European Arthouse Cinema Day set to return on 23 November Cannes 2025 Marché du Film Indie Sales presents a three-star line-up at Cannes HOFF 2025 The Shadow and U Are the Universe win at Estonia’s Haapsalu Horror and Fantasy Film Festival Crossing Europe 2025 Awards The New Year That Never Came and The Flats crowned at Crossing Europe Cannes 2025 Marché du Film Be For Films to sell Love Me Tender in Cannes Cannes 2025/Sponsored Latvia set to shine bright at Cannes, led by Sergei Loznitsa’s competition entry Two Prosecutors Las Palmas 2025 MECAS/Awards Manuel Muñoz Rivas and Joana Carro win awards at the eighth MECAS Cannes 2025 Marché du Film Playtime to present some high-impact and entrancing trump cards at Cannes Production / Funding Italy Shooting begins on Walter Fasano’s Nino, a portrait of scoring maestro Nino Rota goEast 2025 Production / Funding Belgium Wallimage is backing Michaël R Roskam's Le Faux Soir Box Office Slovakia Slovak crime-thriller Černák becomes the highest-grossing film in domestic cinemas Market TrendsFOCUSA busy spring festival season awaits the European film industry. Cineuropa will continue to keep its readers up to date with the latest news and market insights, covering the buzziest events, including Cannes, Kraków, Karlovy Vary, Tribeca, Hot Docs, Annecy, Brussels, Munich and many others Distribution, Exhibition and Streaming – 02/05/2025Slovak crime-thriller Černák becomes the highest-grossing film in domestic cinemasThe second film in the saga about a local mafia boss, directed by Jakub Króner, outgrossed its first part, which dominated Slovak cinemas last year Animation – 30/04/2025Mirko Goran Marijanac • Media sales executive, DeAPlaneta EntertainmentDuring our chat, the exec shared key insights from this year’s Cartoon Next and touched on the current climate for the animation sector Želimir Žilnik • Director of Eighty Plus The Serbian director discusses his deep suspicion of ideologies in relation to his irresistibly charming latest feature, which follows a man whose life spans three political systems Paulina Jaroszewicz • Distribution and marketing manager, New Horizons Association Cineuropa sat down with the Polish distributor to discuss her company’s strategy as well as the connection between its distribution line-up and BNP Paribas New Horizons Festival’s programme Lorcan Finnegan • Director of The Surfer The Irish filmmaker discusses his mystery-thriller, how he created the character with Nicolas Cage and his approach to the use of colours in the film Julien Rejl • General Delegate, Directors’ Fortnight The General Delegate of the Cannes Directors’ Fortnight discusses the 2025 selection and clarifies the debate on its editorial line Privacy Policy The images used on this website have been provided by journalists and are believed to be free of rights if you are the owner of an image used on this website and believe that its use infringes on your copyright We will remove the image in question as soon as possible We have made reasonable efforts to ensure that all images used on this website are used legally and in accordance with copyright laws About us | Contact us | Logos and Banners MissionPartnersTeamDonationsTerms and conditions Personalized news alerts with our mobile app Please subscribe to continue reading… during the second round of the Greensboro Unleash The Beast PBR won his first Professional Bull Riders Unleash The Beast tour event since 2019 in Columbus when he rode to the event championship at the Union Home Mortgage Invitational Montanha, who bucked to the championship at the Billings stop at the Metra in 2018 The 32 year old was second in the first round with an 89-point ride on Saturday The PBR reported that in the second round Sunday Montanha scored an 88.75-point ride and followed with an 88-point effort in the final round for a walk-off win Montanha collected 144 world points and $29,641.27 He vaulted from 29th to 17th in the world standings Vieira had two round wins on the weekend (90.25 and with his second-place overall finish Vieira netted 118 points and $20,098.49 also from Brazil and in his second year on the UTB tour won the 15/15 Bucking Battle on Saturday with a 90.75-point score aboard I'm Legit Too He earned 59 points with the special-round victory the PBR reported The next stop for the premier series is in Manchester BILLINGS — It was only fitting Claudio Montanha Jr Boudreaux Campbell of Texas captured the Velocity Tour Finals event win – As the dirt settled from PBR’s 13th elite series stop inside Greensboro Coliseum Brazilian veteran Claudio Montanha Jr. (Pacaembu Brazil) climbed to the top of the Can-Am Cage hoisting his first Unleash The Beast buckle since 2019 the 32-year-old Montanha put together a perfect 3-for-3 performance at the PBR Union Home Mortgage Invitational presented by Bass Pro Shops en route to the win Finishing second in Round 1 with an 89-point ride on Express Lane (Rickey West Bucking Bulls/2R Bucking Bulls) Montanha parlayed his Saturday night success into a pair of commanding rides to reign supreme on championship Sunday Matching up with Milk Man (TNT Bucking Bulls/Hart Cattle Co) in Round 2 Montanha made the 8-second whistle for an 88.75-point score putting him in the lead heading into the championship round draft The four-time PBR World Finals qualifier selected CopperPoint Swagger (Hart Cattle Co/Hale) as his championship round opponent and blew out of the chutes in front of a crowd full of anticipation Montanha conquered his bovine foe on the way to the whistle for an 88-point ride Montanha earned 144 world points and $29,641.27 with the win Entering the event narrowly inside the Top 30 in the world at No Continuing his chase for his first PBR World Championship veteran Joao Ricardo Vieira (Itatinga Brazil) also went a perfect 3-for-3 on the weekend After winning Round 1 with a 90.25-point masting of Viper (Cord McCoy/Big Sky Bulls Vieira matched up with Texas Blood (Blake Sharp/Henry Wilson) in Round 2 The Round 2 out produced an 84.5-point trip which sent Vieira down to third in the championship round draft Still left with plenty of bull power to choose from the 37-year-old drafted Diddy Wa Diddy (Cord McCoy/Bill McCarty) and turned in his second 90-point ride of the weekend with the 90.75-point score With two round wins on the weekend and the second-place finish Vieira earned 118 world points during the event Vieira’s efforts also earned him a $20,098.49 payday Brazil) was one of only two riders to go 2-for-3 on the weekend and finished third Dang It (Davis Rodeo Ranch/Ed & Cindy Fogle) had helped Eguchi to fourth in Round 1 on Saturday night with an 87-point ride Grey Smoke (Hart Cattle Company) held Eguchi in the Top 3 in Round 2 as the pair danced their way to an 88-point mark Drafting First Down (Hart Cattle Co./Farris) in the championship round Eguchi was ditched by the bovine athlete in 4.21 seconds The 2018 PBR World Finals event winner picked up 70 crucial world points with the bronze finish Three-time PBR World Champion Silvano Alves (Pilar do Sul Brazil) added onto his resurgence in 2021 with another Top 5 finish Alves had covered Hammered Down (Davis Rodeo Ranch/D&H Cattle) in Round 1 for 83.75 points and returned on Sunday to best Roulette (Torres Brother Bucking Bulls LLC) for 84.75 points in Round 2 Walking Tall (Davis Rodeo Ranch) bucked Alves off in 4.78 seconds in the championship round ending Alves’s bid for another late-season event-win Alves also picked up a second-place finish in the event’s 15/15 Bucking Battle on Saturday night matching Detroit Lean (Blake Sharp/Henry Wilson) jump-for-jump on the way to a 90.5-point score The runner-up finish in the special round gave Alves another 49 world points The Brazilian legend earned 93 world points on the weekend Campbell’s 88.75-point ride on Caddyshack (Blake Sharp/Paige Stout/Lukas Banning Bucking Bulls) in Round 1 was enough for the fifth-place finish Campbell hit the ground before the 8-second whistle in Round 2 coming off of Wicked Hou (Hart Cattle Co/Hale/Randy Wood) in 6.2 seconds and again in the championship round in 4.95 seconds as Homegrown (Cord McCoy/Chad Reese) prevailed The highest-finishing American in the event Brazilian Mauricio Gulla Moreira (Gaviao Peixoto the 22-year-old picked up his second 15/15 Bucking Battle win of the season on Saturday night with his 90.75-point ride on I’m Legit Too (Hart Cattle Co/Hale) Earning 59 world points for the victory in the special round Moreira further cemented himself in the No For the first time since the tour’s Fort Worth there was a tie in the event’s YETI Built For the Wild Bull of the Event Both Blue Crush (Cord McCoy/Chad Reese) and Jersey Tuff (McClellan/Lidgard/Hart) turned in 45.75-point outs in the 15/15 Bucking Battle to split the honor PBR’s Top 30 riders and the UTB tour now turn north for next weekend’s Monster Energy Invitational Virginia) captured his career-first event win topping the field at the Pendleton Whisky Velocity Tour’s Wheeling Invitational in West Virginia Beaty was one of six riders to register a qualified ride in Round 1 inside WesBanco Arena covering Zacchaeus (Jenkins Cattle Co.) for 85 points Beaty returned determined on Championship Saturday surging to the top of the event leaderboard after tying for the Round 2 victory compliments of his 87-point effort aboard How Bout It (UTC/Sellers Bucking Bulls) While the Virginia native was unable to conclude the event making the 8-second whistle dispatched by Cutthroat (Cornwell Bucking Bulls) in 2.34 seconds in the championship round Beaty’s initial scores were enough to clinch the golden finish Beaty earned 37 world points and is now ranked No PBR’s finest were also hard at work abroad this weekend as the league’s Australian Monster Energy Tour bucked into BB Print Stadium in Mackay Queensland) won the PBR Mackay Invitational 1 in the race for the 2021 PBR Australia Championship Should Kleier win the national title an unprecedented fourth consecutive time in 2021 the Queensland sensation would tie David Kennedy (Kyogle New South Wales) for most Australian national titles won by one rider in league history Kennedy topped the national standings in 2009-2010 Kleier surged to the golden finish in his home state after covering Meet Ya Maker (Brandenburg/MJ Bucking Bulls) for an event-best 84.5 points in the opening round of competition Kleier was unable to accept a re-ride after Red Flash (Fred Kleier) fell during their Round 2 out and left him with an injury that relegated him to the sidelines was enough to clinch the Clermont-native’s league-leading third event win of the year Kleier is also now tied for most round wins by one rider in 2021 with four For his efforts Kleier earned a critical 65 Australian points and extended his lead atop the national standings PBR UNIONHOME MORTGAGE INVITATIONAL PRESENTED BY BASS PRO SHOP Event Leaders (Round 1-Round 2-Round 3-Event Aggregate-Event Points) 2021 Professional Bull Riders World Standings invaded a small community of riverside peasant farmers and traditional fishermen living beside the Tapajós River in Pará state in the Amazon they’re armed and threatening everyone,” one local resident told Mongabay The beiradeiros say that a large group of garimpeiros arrived in the area disobeying a legal order “not to enter any area occupied by the traditional population of Montanha-Mangabal.” The miners threatened violence against the local inhabitants including the ammunition for our firearms.” The garimpeiros left after making their threats but the beiradeiros now feel vulnerable and isolated Their houses are scattered along the river and it takes an average 20 minutes to row from one to another The community only has two or three radios along about 70 kilometers (43 miles) of river the beiradeiros appealed to the Federal Public Ministry (MPF) an independent branch of the federal government neither the MPF or any government branch has responded The violence against the beiradeiros arose when the 100 families residing in Montanha-Mangabal — frustrated with the government’s failure to mark out the legal borders of their settlement The miners see that process as a serious challenge to their illegitimate land claims The community of Montanha-Mangabal was legally established in 2013, when residents won a long struggle to gain rights to their land Brazil’s National Colonization and Agrarian Reform Institute (INCRA) created a 550 square kilometer (212 square mile) Agro-Extractive Settlement (PAE) for the community the beiradeiros — which is what people living along Amazon rivers call themselves — can go on occupying the land and using it the way their ancestors did in perpetuity told Mongabay: “A few days ago the inhabitants of the PAE began their process of auto-demarcação putting up signs marking out the limits of their land.” that action angered the invading miners because it clearly showed that the riverside land didn’t belong to them That’s when the threats began “within this process in which communities are empowering themselves to defend their territories against illegal mining in the Tapajós region.” Martins sees the Montanha-Mangabal conflict in a broader context: “In the Amazon as a whole the mechanisms for advancing capital in the region always involve agrarian conflicts struggles over the control of natural resources and violence,” he said adding “Wildcat mining is only the advance guard of larger economic interests in the region The miners are used to carry out criminal actions against local families.” Martins sees events in Montanha-Mangabal as being linked to the current political climate in Brazil: “Tension and violence in the Brazilian countryside have increased with the extreme political instability in the country.” Critics of the Temer government hold that the administration’s pro-development policies have emboldened ruralists agribusiness and mining interests eager to exploit the Amazon becoming a PAE was the culmination of a 140-year-struggle for legal recognition The community was settled in the second half of the 19th century when hundreds of poor farmers from impoverished northeast Brazil migrated to the Amazon to tap rubber After the rubber boom went bust in the early 20th century many were trapped without the money for the 2,000 kilometer (1,200 mile) trek home some single men abducted women from neighboring indigenous groups and settled down with them recalled family stories of how her grandfather “stole” her grandmother she added; they brought centuries of indigenous survival knowledge to the rubber-tapper communities without which the communities might have perished This helps explain why beiradeiros communities — which cut only small areas for crops — have some of the best-conserved forest in the Amazon acquired evidence of their long term settlement — reports by priests for the small community to get its land rights recognized the PAE immediately ran counter to the plans of then President Dilma Rousseff who was eager to open the Amazon to large scale economic activities to turn the biodiversity rich Tapajós basin into an industrialized export corridor building a series of dams on the river to generate energy for mining still in the planning stages — would flood land given to Montanha-Mangabal the 100 families will now have to be resettled to a locale acceptable to them Luiz Bacelar Guerreiro Junior, at the time the superintendent for the regional office of Brazil’s National Institute of Colonization and Agrarian Reform (INCRA) and the person who signed the portaria (order) creating the PAE, said: “I am very proud to be ending a struggle like this one Felipe Fritz Braga, a prosecutor in the Federal Public Ministry, independent government litigators, commented: “The recognition of Montanha-Mangabal by the Brazilian state is an unmistakeable act of true and effective agrarian reform It is the first time the federal government recognizes the antiquity of the occupation of this land by these communities and treats them as people having fundamental rights INCRA was obliged to mark out the borders of PAE Increasingly concerned about the way their undemarcated land was being invaded by loggers the community repeatedly appealed to INCRA to fulfil its obligation the beiradeiros decided to mark out their lands themselves in the process known as “auto-demarcação” (self-demarcation) told Mangabay: “This demarcation is happening because a lot of our land is being invaded explained more fully: “We are demarcating the land ourselves so that they [the outsiders] will know where they can go and what land belongs to us They are always saying to us: ‘I don’t know which is my land which is yours.’ So as of today all those people who come from the road all those people will know where they can — and where they can’t — go.” none of the invaders can lay legal claim to the land The settlement lies within the area of Influence of the Transamazon Highway a 100 kilometer (62 mile) strip was claimed by the federal government on either side of the highway Though the beiradeiros are constantly threatened by loggers and miners waving documents that All the land is federal unless the government decides otherwise as in the case of the Montanha-Mangabal PAE The auto-demarcaçāo has lately become a tool for strengthening an emerging alliance between the beiradeiros and local indigenous communities these communities fought each other for control of territory Now they increasingly see themselves as allies with each helping the other with demarcation In 2014, when the Munduruku carried out their own auto-demarcação marking the boundaries of their Daje Kapap Eipi (Sawré Mubyu) indigenous territory Now the indigenous communities are reciprocating “We and the beiradeiros both depend on this forest and this river,” said Juarez Saw Munduruku the cacique (chief) of Sawre Muybu village “We are threatened in the same way by government projects I am in debt to Montanha-Mangabal and I have come to pay that debt And I have brought 23 male and female warriors with me.” Both the Munduruki cacique, Juarez Saw Munduruku, and the beiradeiro Chico Caititu are worried about the hydroelectric dams planned for the Tapajós River — which scientists say is an environmental “crisis in the making.” Of particular concern is the nearest one where studies for the dam’s licensing are due to be finished next year the Jatobá dam will have a severe impact on both the Munduruku and the beiradeiros Other Munduruku groups, not directly affected by Jatobá, also helped in the recent demarcation. Two leaders from the Satere Maue community undertook a five-day journey to visit and express their support for Montanha-Mangabal’s demarcation. They are involved in their own struggle, so far successful, to stop large São Luiz do Tapajós dam — shelved by IBAMA in 2016 after a major public campaign against it It is too soon to gauge the reaction of other beiradeiro communities and indigenous communities to the violence happening in Montanha-Mangabal Today the beiradeiros in Montanha-Mangabal increasingly feel part of a broader community which is resisting government and business incursions into the region and standing against the rising wave of violence a beiradeiro playing an active role in the demarcation this alliance we have made with the Munduruku Correction: When this article was originally published several photos were credited erroneously to Ailen Vega but were actually shot by Fernanda Moreira FEEDBACK: Use this form to send a message to the author of this post The “fortress conservation” model is under pressure in East Africa as protected areas become battlegrounds over history and global efforts to halt biodiversity loss Mongabay’s Special Issue goes beyond the region’s world-renowned safaris to examine how rural communities and governments are reckoning with conservation’s colonial origins and trying to forge a path forward […] Ohio – As the lone rider to deliver a flawless performance inside the Schottenstein Center Brazil) earned his first PBR (Professional Bull Riders) Unleash The Beast event win of the 2019 season victorious at the Wrangler Long Live Cowboys Classic Having covered Night Sweats (Plummer/Hart Cattle Co.) for 85.75 points in Round 1 on Saturday night the 29-year-old stepped foot on the campus of The Ohio State University on Championship Sunday fifth overall in the event His climb to the top of the leaderboard continued in Round 2 when he made the 8 aboard Millenium (Torres Buckign Bulls) for 76.5 points As one of five riders to cover both of his long-round draws the surging Brazilian earned the fifth pick in the championship round draft (TNT Bucking Bulls/Hart Cattle Co.) who he had bucked off in 3.36 seconds at the premier series stop in September 2018 in Austin taking him to the 8-second whistle for a score of 87.25 points Montanha leaves the Buckeye State with $32,467.86 in addition to 470 world points Backed by a dominant performance in the event’s final rounds Texas) finished second to collect $20,097.86 Rebounding from a 4.84-second buckoff of Cool Customer (D&H Cattle/Flinn) in Round 1 the Texan won Round 2 courtesy of an 87.5-point ride atop Nailed (Broken Arrow Bucking Bulls) He then cemented his runner-up finish with an 89.25-point ride on Milky Chance (Hart Cattle Company) in the championship round Teel climbed one position in the world standings to No After beginning the event 1,025.83 points back Competing for the first time since breaking his jaw two weeks ago Brazil) earned his second third-place finish of the season in Columbus The veteran Brazilian began the final night of action second overall after covering Peep Show (Cornwell Bucking Bulls) for 87.25 points in Round 1 Despite bucking off Steer Clear (Creekbend Bucking Bulls) in the second round in 3.47 seconds making the 8 aboard Bottoms Up (TNT Bucking Bulls/Hart Cattle Co.) for 88 points Aparecido also gained 290 crucial points towards the world standings 21 and 247.5 points in front of the cutline With an 87.5-point trip on Sugar Boom Boom (Cornwell Bucking Bulls/Circle G) at his back Kolbaba retained his spot atop the event leaderboard after the second round taking Jungle Can Do (Dakota Rodeo/Chad Berger/Clay Struve/ Diamond Willow) to the whistle for 87 points Kolbaba selected Big Black (K-C Bucking Bulls/Joe & Nina Webb) who has helped four riders earn event titles thus far in 2019 dispatched by the bovine athlete in 4.36 seconds He returns to the Pacific Northwest $11,747.86 richer Kolbaba’s best of 2019 on the elite Unleash The Beast Rounding out the Top 5 was 2018 PBR World Finals event winner Marco Eguchi (Poa netting $9,067.86 along with 210 world points After recording the seventh-best score in Round 1 an 85.25-point ride on Bandit (Mike Miller Bucking Bulls) Eguchi was bested by Lefty (Bill Henson/Gene Owen) in 4.26 seconds in the second round Determined to reach the 8 again inside the Schottenstein Center Eguchi took Losing My Religion (Broken Arrow Bucking Bulls) to the whistle for a championship round-winning 89.5 points The round win was his second of the season earning his first in Round 2 of the Little Rock the out was the first qualified ride he had earned atop Losing My Religion in three meetings The bovine athlete had previously bucked him off in 5.69 seconds at the premiere series event in Tulsa also his top event performance of the year The Top 3-ranked riders in the world standings remained constant following the Wrangler Long Live Cowboys Classic Leme finished 10th after going 1-for-3 to net $2,217.86 and 45 world points tying for sixth after going a matching 1-for-3 Sky Harbor (Chad Berger/Clay Struve/Wilks Ranch/Paradigm Bull Co.) and SweetPro’s Bruiser (D&H Cattle Co./Buck Cattle Co.) tied for the YETI “Built for the Wild” Bull of the Event after recording matching 45.75-point scores Sky Harbor earned the marks in the championship round for his 3.85-second buckoff of Leme while SweetPro’s Bruiser’s were recorded in Saturday’s 15/15 Bucking Battle when he dispatched Outlaw in 7.43 seconds While the honor is the first of the season for Sky Harbor it is SweetPro’s Bruiser’s second having earned the title at the most recent stop in Billings SweetPro’s Bruiser remains atop the race for World Champion Bull 2 Fearless (D&H Cattle/Buck Cattle/Tommy Julian) two bovine athletes extended their premier series buckoff streak to 32 after dispatching their rider opponents in Columbus Heartbreak Kid (D&H Cattle/Buck Cattle/Erwin Cattle) made fast work of Mason Taylor (Maypearl while Bad Touch (Jo Z Bucking Bulls/K-C) sent Ryan Dirteater (Hulbert Oklahoma) to the dirt in 7.7 seconds in the championship round The all-time premier series buckoff streak is held by three-time PBR World Champion Bucking Bull Bushwacker (Julio Moreno/Richard Oliveira) with 42 consecutive buckoffs Fans can relive all the action on-demand on Monday Each chasing their career-first Velocity Tour Championship – Riding with the support of a sold-out Saturday night crown in Hampton Virginia) tied for the event win at the PBR (Professional Bull Riders) Pendleton Whisky Velocity Tour’s Hampton Classic inside Hampton Coliseum Montanha began his outing in the Old Dominion State with a bang topping Round 1 with an 88-point effort atop Two Hands (Frenzel/King) Positioned atop the event leaderboard as the championship round began Montanha was next tasked with Here I Am (Cash Money Bucking Bulls) the charismatic Brazilian reached the 8 for 86.5 points to clinch the co-event win Montanha’s golden effort garnered him 110 Velocity Global points as he looks to earn his career-first PBR Pendleton Whisky Velocity Tour Championship this May in Corpus Christi Lane’s 2-for-2 victory netted him 109.5 Velocity Global points marked 86 points atop Krampus (Blue Ridge Bucking Bulls/M&B) Virginia’s own Lane surged to the top of the standings when he recorded the high-marked ride of the tour stop in the championship round outlasting Eager Snake (Triple C Bucking Bulls) for 88.5 points Third was surging Brazilian Guilherme Valleiras (Pirassununga Rounding out the podium as the last rider to be flawless inside Hampton Coliseum Valleiras rode You’re Right (Topline Steel Buildings/Barrett) for 83 points in Round 1 and Shakira (Cannon Cattle Co.) for 87.5 points in the championship round Chambers’ 87.5-point score aboard Happy Gambler (Cash Money Bucking Bulls) in Round 1 netted him 39 Velocity Global points Rounding out the Top 5 in fifth was Elijah Mora (Wiggins Courtesy of his 86-point effort on Area 51 (LH Cattle Co./Sho-Me Rodeo) Mora earned 33.5 Velocity Global points at the PBR Hampton Classic The PBR Pendleton Whisky Velocity Tour next travels to Knoxville The PBR Knoxville Invitational gets underway at 7 p.m Event Leaders (Round 1-Round 2- Event Aggregate-Event Points) Montanha leads second-place contenders Hunter Ball and Bennie Shetler by 0.5 points ahead of Championship Saturday for the PBR ZipRecruiter Capital City Classic – In front of a raucous Friday night crowd in Charleston winning Round 1 of the PBR (Professional Bull Riders) Pendleton Whisky Velocity Tour inside the Charleston Civic Center to surge to an early lead in the ZipRecruiter Capital City Classic led the pack of competitors compliments of an 85-point score earned aboard Jeff (Julian Cattle) The 8-second effort garnered the charismatic Brazilian a crucial 28 Velocity Global points Montanha is within the sights of Hunter Ball (Carsonville The duo of cowboys trail the top position by a mere 0.5 points after each delivered an 84.5-point score to net 17.5 Velocity Global points Ball conquered Next Question (UTC/Sellers Bucking Bulls) while Shetler went the distance atop Area 51 (LH Cattle Co./Sho-Me Rodeo) Lima reached the whistle atop Whip (White/Knapp Ranch) for 84 points to leave the Charleston Civic Center with 16 Velocity Global points North Carolina) rounded out the Top 5 in fifth Drawing One Boot Patches (Obernagel/Sho-Me Rodeo) Stepp matched the animal athlete jump-for-jump en route to an 83-point score earning him an accompanying 15 Velocity Global points Three additional contenders also delivered scores in Round 1 of the PBR ZipRecruiter Capital City Classic each collecting 13.5 Velocity Global points the pair covered Jake Brake (Clark View Farms/Jenkins Cattle) and Blackened (Crooked Crown Bucking Bulls/Braswell Bucking Bulls) He bested Sundance (Damn Skippy Ranch/S&S Bucking Bulls) for 79.5 points to earn 11 points in the race for the 2023 PBR Pendleton Whisky Velocity Tour Championship Action for the PBR ZipRecruiter Capital City Classic will conclude with Round 2 and the championship round on Saturday Photo courtesy of Andre Silva/Bull Stock Media we continue to take a look at the PBR from a different angle with the Women of the PBR As we continue with Finals Week and roll into World Finals These ladies play a variety of important role both in front of and behind the scenes AM: Claudio was already a friend of my brother They were both competing in bull riding so they traveled together on the weekend But I had only heard of Claudio when my brother would talk about him at home he was at the lake fishing with my brother I arrived at the lake and I was surprised he was here PBR.COM: What was your first impression of Claudio AM: I thought he was handsome when I first saw him because he was kind of like that because of my brother PBR.COM: What was the first PBR event you attended AM: In Brazil it was the Americana and here in the United States it was in Las Vegas PBR.COM: How were you introduced to the Western sports world AM: I was raised in the interior of São Paulo and there are many rodeo events And I had a brother who was very good now and then I did not watch him much but I always saw the reports AM: It’s been two years since I came to the United States and I do not have that same routine I had in Brazil But here every day I go to the gym and I like it a lot I help with homework every day with Joao Victor’s school and I like it very much We go to the mall even if I do not understand English It is very fun because he wants to go in all the movies I take him and his friends to the movies and I go along and watch the movie So I am adapting here and learning a word every day and I like it selling bank financing and Claudio worked with the computer He had the dream since childhood to come here to the United States and to be a world champion so I wanted to follow Claudio’s dream he got to the United States and I came here with him I would like to have a store for myself because I love the business of selling and talking to customers I know one day I'm going back to Brazil and I'm going to have this chance because my family is all there and that's how I think I want to see Claudio accomplish his childhood dream PBR.COM: How does Claudio support your endeavors Joao wakes up at 7 o'clock and Claudio wakes up every day so he helps me a lot with Joao He helps a lot here at home with different food we want to make And so we go and help each other in our day-to-day PBR.COM: What do you see trending in the fashion industry currently AM: Women think they always want to be updated in fashion I think that is good because I have my style I'll feel comfortable with certain clothes and I have a lot of people that follow me and it can sometimes be crazy like when someone direct messages me: “Aline where did you buy those pants we loved your look.” Or like when I posted the Montana Silversmiths photos how much would it be for you to send me one?” I alone have my style so I always like updating and what I feel in PBR.COM: What is your favorite jewelry accessory I do not go without a bracelet or without an earring cannot go without my favorite bracelet and earrings PBR.COM: How would you describe your style PBR.COM: Describe your style difference between every day and what you wear to an event we work out then I go back in a bath and put on more comfortable clothes Staying at home you always wear comfortable clothes One thing is that before I go to the event PBR.COM: Do you have someone you look to in terms of their style AM: I do not have a specific reference in a single person but I look at a woman like “look at what beautiful clothes.” If I like and find that it looks good on me because I have my own style I might find that I loved those pants or I loved that necklace PBR.COM: How did you select the pieces in your Montana Silversmiths collection I really like black and I really like turquoise blue The pieces that I chose go with everything It can be used both at night and day-to-day depending on the occasion or the place you go I like all the pieces but I chose this because I like the blue I like things that attract attention and can be used with everything You can check out Aline’s collection with Montana Silversmiths here Be sure to catch next week’s Montana Silversmiths’ Women of the PBR as we talk with another of the Women of the PBR The Alchemist: We are images, dreams, photographs. We must not stay here. Prisoners! We shall break the illusion. This is Maya! Goodbye to the Holy Mountain. Real life awaits us. Your Ads Privacy ChoicesIMDb Brazilian rookie Joao Augusto Cezere beat out a crowded field of BFTS stars including Claudio Montanha Jr. Joao Ricardo Vieira and Guilherme Marchi to claim the PBR Brazil Iron Cowboy title at the famed Americana rodeo BRAZIL – Winning the title of Iron Cowboy requires a heroic effort and sometimes even the PBR’s elite riders fall short it was a young rookie who was flying high as João Augusto Cezere beat out the field to win Iron Cowboy at Brazil’s famed Americana rodeo Cezere (6.88 seconds) beat out Built Ford Tough Series rookie sensation Claudio Montanha Jr (2.1 seconds) based on buckoff time for his first PBR Brazil victory during Round 4 of the head-to-head "It's a mix of feelings,” Cezere told PBR Brazil’s Jorge Cardoso “I cannot believe that I won my first event in PBR Brazil and even more in Americana who is a massive fan of the comic book superhero Superman emerged from a crowded field that featured many of the BFTS’ Brazilian superstars including 2008 World Champion Guilherme Marchi and 2013 Rookie of the Year Joao Ricardo Vieira With the iconic Superman “S” symbol emblazed on his riding vest the 22-year-old rode Different for 86.25 points in Round 2 on his way to the title Cezere has worn the symbol since he started riding five years ago and has adopted “Superman” as a nickname in Brazil who is currently ninth in the world standings Vieira finished fourth overall in the event for 20 world points after riding Gringo for 85.75 points in Round 1 It was a dream for Cezere to even compete in PBR Brazil let alone alongside some of his biggest heroes "I've struggled a lot to be here and compete with competitors that I'm a fan of like Guilherme Marchi Juninho dos Índios and João Ricardo among others,” Cezere said Lucas Divino won the PBR Brazil Iron Cowboy qualifying event earlier in the weekend by going 2-for-2 44 in the world standings and is 80.41 points outside of the Top 35 To learn more about PBR Brazil, check out pbrbrazil.com  Between 1,000 and 1,400 people are estimated to have died The US, Britain and other western governments have pinned the blame on the Syrian government; Russia has accused the rebels. Hersh describes this as part of a "false flag" operation designed to draw the US into a conflict with Syria In his 6,000-word article Hersh relies heavily on single and constructs a narrative in which the Turkish government was responsible for the largest chemical attack since the one carried out by Saddam Hussein on Halabja in 1988 and it brings the reliability of his sources and conclusions into question Hersh makes no mention of the munitions used on 21 August, something that is key to understanding the attacks. In an interview for Democracy Now! he states that the weapons were both homemade and not in Syria's arsenal Two types of munitions were used on 21 August and are linked to the dispersal of sarin gas. Both were recorded in a report by the UN and the Organisation for the Prevention of Chemical Weapons (OPCW) and tested positive for signs of sarin One was a Soviet-era M14 140mm artillery rocket certainly not a "homemade" munition and the second was a munition that was widely unknown Studying videos and photographs posted by opposition and pro-government sources has allowed researchers to piece together a great deal of information about these rockets We know they are referred to as "Volcano" rockets and come in at least three sizes: 107mm and a much larger type based on a 220mm rocket motor It is also clear that there are both explosive and chemical versions as well as evidence of their use by the Syrian military from late 2012 In all examples the rockets have been fired at the opposition and appear to share an identical design even pro-Hezbollah sources started posting images of Volcano rockets in action It is quite clear that no matter how "homemade" Hersh believes the rockets to be they have been used by the Syrian military for more than a year When questioned about this in a recent interview with the Turkish website Diken Hersh dismissed the Volcano rockets seemingly because he believes a range of "a mile" somehow means they should be discounted as important to his narrative Hersh refers to the work of Ted Postol and Richard Lloyd who believe the range of the rockets is about 2km But this range issue isn't the problem Hersh appears to think Video footage from both sides of the conflict has allowed researchers to accurately find the positions of government controlled areas on 21 August. The Russian-language news site ANNA News posted two dozen videos showing "Operation al-Qaboun" a Syrian government military operation running from June to August 2013 they were able to film the progress of the operation to clear positions between Jobar and Qaboun a strip of land about 2km away from the 21 August impact sites Videos from opposition groups show the other side of the fighting including attacks on checkpoints and government movements Based on this information it appears that the front lines were about 2km away from the furthest impact sites of rockets used on 21 August Only two rockets landed at the 2km maximum range described by Lloyd and Postol with the reported impact sites of the remaining rockets being between 1.5km-1.8km away It has been possible to confirm the precise impact locations of some of the rockets by a combination of GPS information and around a dozen impact sites were reported by local groups in eastern Ghouta Hersh's belief that the 2km rocket range is enough to dismiss them from his narrative is clearly misguided Despite Hersh's claims we can clearly see that the rockets were used by the Syrian government and within range of government controlled territory But what about his claim of Turkey helping Jabhat al-Nusra Seven issues need to be addressed: difficulty of manufacture Anyone who claims otherwise is oblivious to both history and chemical engineering the US and the former Soviet Union took years to perfect the process Its production requires a number of complex steps and the ability to handle highly dangerous chemicals at very closely controlled high temperatures and pressures There is no evidence anyone has come up with any sort of streamlined method to manipulate the molecules to make sarin but it would have needed to be closer to that than the size of a house Of the panoply of chemical warfare agents available to modern science and engineering are arguably easier to produce; mustard or lewisite are easier and use less technology Numerous toxic industrial chemicals which might "fly under the radar" of non-proliferation regimes could be used as weapons To make this operation work it is going to take a lot of highly trained people It would cost many tens of millions of dollars When the rebel factions are so stretched for resources Lavish expenditure must raise a paper trail somewhere; there would be order books and receipts You don't turn precursor material magically into sarin: you need about 9kg to end up with 1kg of sarin It is simply assumed that things like phosphorus trichloride and thionyl chloride just get summoned up in vast quantities without someone noticing Most commentators on this issue have also forgotten about something called conservation of mass If you use 9kg of material to synthesize 1kg of sarin you end up with 8kg of waste There are also the logistics of getting a lot of sarin into rockets and getting those rockets from Aleppo to Damascus They need to be concealed not just from the Syrian regime but from other rebel factions and perhaps even your own people who might desert get captured or say silly things on YouTube videos There is deathly silence from Aleppo and we only find out about it from Hersh There are important physical clues found in the traces of sarin at the impact sites of the 21 August rocket attack a chemical with no history of use in nerve agent production But hexamine can be used as an acid scavenger and thus its presence could be explained due to its use as an additive to the sarin This idea has been reinforced by both the admission of the Syrian regime that they used hexamine as part of their formula and by Syria's declaration to the OPCW of an inventory of 80 tonnes of hexamine specifically as part of their chemical weapons program they could have omitted it from their declarations Hexamine in field samples plus hexamine in Syrian inventories plus an admission that hexamine was in their recipe seems a compelling case for tying the Sarin in the field to the Syrian regime How would an Aleppo-based rebel factory somehow come up with the same exact idea all these points add up to a very high degree of improbability Isn't it more probable that the Sarin came from the people who confessed to having a Sarin factory fired from areas controlled by the government 2km away from the impact sites in munitions the government had been using since 2012 Miranda: What we see and what we seem are but a dream, a dream within a dream. grains merchant Archer-Daniels-Midland Co ADM.N said on Tuesday it has carried out the largest soybean shipment in the history of the Ponta da Montanha Grain Terminal (TGPM) located in the northern Brazilian city of Barcarena as it shipped 84,802 tonnes in a single vessel It also represented the largest volume ever shipped on a grain vessel from ports located in the Amazon Basin “This showed us that we have one more option to move soybeans through the TGPM using our own vessel… This is definitely something we will do again more often” ADM’s South America Logistics Director which is 237 meters (777.56 ft) long and 40 meters wide set sail last week for the port of Rotterdam in the Netherlands The company said all the soybeans moved will be crushed by ADM itself The previous record for shipments from Brazil’s northern region was set at the port of Santarem in 2020 when 82,531 tonnes of soybean were moved in a single vessel (Reporting by Nayara Figueiredo; Writing by Gabriel Araujo; Editing by Bernadette Baum) Sign up for gCaptain’s newsletter and never miss an update and updates delivered daily straight to your inbox Spot rates across all the major east-west deepsea trades continued their downward descent this week although it has become increasingly clear that widespread blanked sailings on the transpacific trade managed to stave off a complete crash The Mediterranean Sea has become the world’s fifth Emission Control Area (ECA) for sulphur oxides starting May 1 adopted by the International Maritime Organization (IMO) Small-value packages shipped to the US from China will no longer be exempted from tariffs starting Friday when President Donald Trump’s move against an exception he called a “big scam” takes effect Subscribe to gCaptain Daily and stay informed with the latest global maritime and offshore news Stay informed with the latest maritime and offshore news For general inquiries and to contact us,please email: [email protected] To submit a story idea or contact our editors, please email: [email protected] For advertising opportunities contactEmail: [email protected]Phone: +1.805.704.2536 Essential news coupled with the finest maritime content sourced from across the globe Look out for your first newsletter in your inbox soon We help you navigate a myriad of possibilities Sign up for our newsletter for the best of the city By entering your email address you agree to our Terms of Use and Privacy Policy and consent to receive emails from Time Out about news Sign up for our email to enjoy your city without spending a thing (as well as some options when you’re feeling flush) Our newsletter hand-delivers the best bits to your inbox Sign up to unlock our digital magazines and also receive the latest news By entering your email address you agree to our Terms of Use and Privacy Policy and consent to receive emails from Time Out about news, events, offers and partner promotions. Lisbon Does it make sense for a Nepalese restaurant to steal the name of the most famous mountain in your country Does it make sense that it has a brother and gives it the same name And that there are three more with the same nomenclature in the city Do not get confused: the two Alvalade ones belong to the same group and are great places to sample food from Nepal And do not forget to warn about the intensity of the spice you want in the order Perfect for: discovering the happiest waiters in Lisbon.Must try: saag paneer Thanks for subscribing! Look out for your first newsletter in your inbox soon! facebookinstagramAbout us Contact us The WIPO Arbitration and Mediation Center and Internet Commerce Association UDRP Review Project Team have published their initial report The full initial report and executive summary of recommendations are available on WIPO’s website The core message is to carefully maintain the good functioning of the UDRP The purpose of the Review Project is “to provide ICANN with assistance in finding a more efficient and practical way forward by providing crucial background information that can help direct the Phase 2 Review” of Rights Protection Mechanisms being carried out by ICANN The report is based on input from 16 UDRP experts and 28 specific subject matter experts are: appeals layer; changing “and” to “or”; supplemental filings; expedited or summary procedures; remedy: true cancellation; panellist appointment accreditation and quality; codification of case law; free speech; and decision format Feedback on the report can be provided until 27 June 2025 via WIPO’s website here WIPO and ICA will submit a final report to ICANN after that The report was showcased at the conference marking the 25th anniversary of the UDRP A number of MARQUES members joined either in person or online Memorandum Circular No 2025-009 sets forth the Rules and Regulations for the Declaration and Creation of the Register of Well-Known Marks in the Philippines and institutionalizes an administrative procedure of having a mark declared as well known the only way to have a mark declared as well-known was when a competent authority such as the Bureau of Trade Marks or a court declared it as such in the course of opposition or litigation In determining whether a mark is well known the following criteria or any combination of them may be taken into account any interested party may file a written observation once the application is published or upon finality of a decision resolving a third-party observation the Intellectual Property Office of the Philippines (IPOPHL) shall issue a certificate of well-known mark declaration and shall cause the said declaration to be entered in the Register of Well-Known Marks The IPOPHL shall also publish the contents of the Register If a trade mark previously declared as well-known by a competent authority in the course of litigation is not included in the Register the trade mark owner or their authorised representative may file a manifestation to such effect with the Bureau of Trade Marks attaching evidence of the declaration by the competent authority The mark previously declared as well-known may then be included in the Register upon the payment of the prescribed fees For marks previously declared by a competent authority as well-known proof of continuous commercial use must be submitted within five years from the date of effectivity of the circular the required proof of use must be submitted as provided further below Failure to submit the requisite manifestation and the proof of continuous use shall result in non-recordation of the previously declared well-known mark in the Register of Well-Known Marks The declaration of well-known mark shall be for a period of 10 years renewable for periods of 10 years The registrant is required to prove continuous use in commerce by submitting pieces of evidence such as receipts bills of lading and photos of the product bearing the mark and well-known status by submitting proof such as advertisements certificates of registrations and financial statements within one year from the fifth anniversary of the declaration and upon each renewal If the mark declared as well known is already registered with the IPOPHL only the evidence of well-known status shall be required within one year from the fifth anniversary of the declaration and upon each renewal without prejudice to the submission of the Declaration of Actual Use requirements under the Trade Mark Regulations Blog post written by Joseph Lyle K Sarmiento, Partner, BCCSLAW in Manila and a member of the MARQUES International Trade Mark Law and Practice Team The Czech Arbitration Court recently ruled in favour of the EUIPO in a UDRP proceeding concerning the domain name euipp.com the Panel found it was the respondent's intention to deceive and divert consumers as evidenced by their dissemination of scam emails sought to take advantage of the EUIPO's goodwill and credibility luring internet users into using services that may appear to be affiliated with the Office The panel acknowledged EUIPO’s reputation and the widespread recognition of the EUIPO mark, which is itself registered as an EU trade mark and as an international mark The respondent did not file an effective response to the complaint The panel concluded that: the disputed domain name was confusingly similar to EUIPO’s trade mark; the respondent had no right or legitimate interests in the disputed domain name; and it had registered and was using the disputed domain name in bad faith In a post on its website EUIPO stated: “This is the first time the Office has successfully relied on its registered EUTM in a domain name dispute resolution process The ruling demonstrates how IP rights provide tangible enforcement benefits in holding scammers accountable for misleading consumers.” the EUIPO has intensified efforts to tackle fraudulent activities EUIPO has also secured criminal court rulings in Sweden and Germany in cases involving scams For more information on misleading payment requests, view the dedicated webpage on EUIPO’s website or speak to a member of the MARQUES Anti-Fraud task Force In 2021 the UK IPO launched its five-year 'Transformation Programme' to modernise and aggregate its services for different categories of intellectual property The findings of the 2nd Consultation regarding the Programme were published last Thursday (10 April 2025); the responses relate to proposed changes in the following areas: The Programme aims to create an online service where trade mark and design documents will be published and available for inspection online much like the UK IPO's existing service for inspecting patents This is a significant update from the current system where trade mark and design documents have to be requested directly from the IPO The response from the consultation was favourable though the IPO notes the concerns regarding confidentiality and potential data scraping by third parties The series mark service (in place currently) allows for a single trade mark application to contain up to six variations of a mark the marks in question must resemble each other as to their material particulars and differ only as to matters of a non-distinctive character not substantially affecting the identity of the trade mark about 40% of series mark applications do not meet these requirements The IPO intends to discontinue the system for series marks and requested responses on its user experience the UK IPO intends to remove the series mark service: it estimates that a small proportion of applicants would need to make additional applications and most customers would benefit from the simplification The majority of the responses favoured the system Respondents found the service practically very useful given its low cost and administrative benefits but some were confused about whether a series mark provides any actual or perceived additional protection compared to a standalone trade mark Many respondents said that six is a good maximum number for a series There was general opposition to the removal of the series service altogether because applying for standalone marks would come at an increased cost (both in terms of application fees and enforcement costs) and might create difficulties for existing It would also put an end to the high volume of invalid series applications The IPO says the costs of applying are “already low” The IPO believes that there is an imbalance between the high number of IPO Tribunal proceedings and the relatively low number of parties using its commercial mediation service It seeks to encourage mediation by introducing Mediation Information and Assessment Meetings (MIAMs) into the IPO Tribunal process in which parties would be briefed on the benefits of ADR and can see if their case is suitable to be mediated The IPO says it will introduce a Pilot MIAMs scheme for proceedings where there are private individuals on both sides Responses were broadly in favour of MIAMs taking place during proceedings but warned that they would not like being “forced” to mediate The IPO intends to launch its updated digital patent service later in 2025 followed by its online trade mark and design service in 2026 Report by Gavin Stenton, Chair of the MARQUES International Trade Mark Law and Practice Team The Team will continue to monitor this topic and report on any further developments The 2025 Kay Uwe Jonas Memorial Lecture was delivered by Lydia Gobena during the MARQUES Team Meetings in Barcelona in March The topic of Lydia’s lecture was “The Case for Creativity” she described “how participating in creative endeavours outside of your practice can benefit you professionally and personally” Lydia (a member of the MARQUES Famous and Well-Known Marks Team) drew on her own experience of jewellery making from her first weekend class at a prestigious fashion school in 2001 and making jewellery for friends and family to launching a small business and exhibiting in galleries and exhibitions She also illustrated her talk by wearing items of jewellery she had made “It has been more than two decades since I first stepped in to the jewellery marking studio and it has been one of the most educational and satisfying adventures I have undertaken I learned several valuable lessons,” she said These lessons include: a greater appreciation for clients’ needs the need for flexibility and taking a business perspective; developing foresight problem-solving and imagination; managing anxiety; coping with disappointment; finding a safe space to make mistakes; being authentic and being comfortable with who you are; and seizing the moment “Some of the most interesting and beautiful things that you can create will be a product of your mistakes,” said Lydia I may even rejoice in those mistakes when they turn out differently than what I had imagined instead of dwelling on them or amplifying them I try to figure out how to avoid them next time - or glean something positive from an otherwise negative situation.” Lydia dedicated the speech to the memory of Kay Uwe Jonas Cory Joshua Germaine Alleyne and her mother Abebetch Gobena She concluded: “Live your life fully you might learn some things and end up finding joy.” The full text of Lydia’s speech is available to read on the MARQUES website here WIPO is hosting a conference to mark the 25th anniversary of the Uniform Domain Name Dispute Resolution Policy (UDRP).It will take place in Geneva Switzerland on 23 April this year with online attendance also possible According to WIPO: “The conference will include a retrospective on the UDRP taking stock of jurisprudential trends and looking ahead to the planned review of the UDRP by ICANN Sessions will also look at ADR systems for blockchain domains and DNS industry and enforcement forecasts including the potential impacts of AI.” The conference will include opening remarks by WIPO Director General Daren Tang and Assistant Director General Marco Alemán followed by sessions on: the UDRP in numbers; UDRP retrospective (a global blueprint); WIPO’s ccTLD program; UDRP review expert group report; WIPO Overview 3.1; WIPO’s e-filing system and case platform; ICANN’s new gTLD program; applying the UDRP model to Web3/Blockchain domains/Alt Roots; and the future of DNS enforcement: AI tools/state of play There will also be time set aside for open discussion The conference is open to the public including brand owners academics and other domain name and Internet stakeholders.  On-site attendance includes lunch and a cocktail reception For more information on the program and speakers, visit WIPO’s website here To register to attend online, click here To join the waiting list for on-site attendance, email arbiter.meetings@wipo.int EUIPO has published details of its approach to artificial intelligence including information on its current use of AI tools The information is available on the EUIPO website here. There is also a video by EUIPO available on YouTube The information on the website sets out EUIPO's responsible approach to AI which is bult on five pillars: AI as a strategic enabler; adopting AI in a structured way; applying AI in a practical way; cooperating and sharing knowledge on AI; and introducing AI with a human-centric approach EUIPO says it uses AI "to empower staff and efficiency" and builds AI systems that are "transparent with strong safeguards to protect privacy and data" It adds: "Our commitment to AI governance focuses on ensuring that all AI solutions are developed with ethics we aim to drive meaningful change across the EU enhancing both our services and the experiences of those we serve." AI tools are currently used at various stages of the trade mark lifecycle (see chart below) eSearch plus and eTranslation for eSearch Case Law Illustration from EUIPO website used with permission HomeMANAGED LANDSForest and Trust Lands The World Heritage Centre is at the forefront of the international community’s efforts to protect and preserve World Heritage partnerships for conservation Ensuring that World Heritage sites sustain their outstanding universal value is an increasingly challenging mission in today’s complex world where sites are vulnerable to the effects of uncontrolled urban development Our Partners Donate Take advantage of the search to browse through the World Heritage Centre information known as 'the loveliest mountain of China' was acclaimed through art and literature during a good part of Chinese history (e.g the Shanshui 'mountain and water' style of the mid-16th century) Today it holds the same fascination for visitors painters and photographers who come on pilgrimage to the site which is renowned for its magnificent scenery made up of many granite peaks and rocks emerging out of a sea of clouds Célébrée durant une bonne partie de l'histoire chinoise dans l'art et la littérature (par exemple dans le style shanshui « montagne et eau » exerce toujours la même fascination sur les visiteurs les peintres et les photographes d'aujourd'hui venus en pèlerinage dans ce lieu enchanteur connu pour son paysage grandiose composé de nombreux rochers et pics granitiques émergeant d'une mer de nuages يُحتفى بجبل هوانغشان أجمل جبال الصين على مرّ التاريخ في الفنون والأدب (مثلاً في تحفة "جبل وماء" من النسق الشانشوي أواسط القرن السادس عشر)، وهو لا يزال ينُشده الزوّار والأدباء والرسّامون والمصوّرون المتوافدون في رحلةِ استجمام إلى هذا المكان الآسر المعروف بمناظره الرائعة المكوّنة من العديد من الصخور والقمم من مادة الغرانيت المطلة عبر بحرٍ من الغيوم 黄山被誉为“震旦国中第一奇山”。在中国历史上的鼎盛时期,通过文学和艺术的形式(例如16世纪中叶的“山”、“水”风格)受到广泛的赞誉。今天,黄山以其壮丽的景色——生长在花岗岩石上的奇松和浮现在云海中的怪石而著称,对于从四面八方来到这个风景胜地的游客、诗人、画家和摄影家而言,黄山具有永恒的魅力。 часто использовался в литературе и искусстве (к примеру В наше время гора также привлекает посетителей которые наслаждаются видом живописных гранитных пиков ha sido celebrada por artistas y literatos durante gran parte de la historia del paí­s (por ejemplo en el estilo "montaña y agua" del Shanshui Su grandioso paisaje de rocas y picos graní­ticos que emergen de un mar de nubes sigue ejerciendo hoy el mismo poder de fascinación sobre los numerosos viajeros pintores y fotógrafos que acuden en peregrinación a visitarla often described as the “loveliest mountain of China” has played an important role in the history of art and literature in China since the Tang Dynasty around the 8th century when a legend dated from the year 747 described the mountain as the place of discovery of the long-sought elixir of immortality This legend gave Mount Huangshan its name and assured its place in Chinese history Mount Huangshan became a magnet for hermits fascinated by its dramatic mountainous landscape consisting of numerous granitic peaks emerging through a perpetual  sea of clouds During the Ming Dynasty from around the 16th century this landscape and its numerous grotesquely-shaped rocks and ancient gnarled trees inspired the influential Shanshui (“Mountain and Water”) school of landscape painting providing a fundamental representation of the oriental landscape in the world’s imagination and art located in the humid subtropical monsoon climate zone of China’s Anhui Province and covering an area of 16,060 ha with a buffer zone of 49,000 ha is also of outstanding importance for its botanical richness and for the conservation of a number of locally or nationally endemic plant species some of which are threatened with extinction Criterion (ii): The cultural value of Mount Huangshan’s scenic landscape first entered the Chinese imagination in the Tang Dynasty and has been held in high esteem ever since The mountain was named Huangshan (Yellow Mountain) by imperial order in the year 747 and from that time on attracted many visitors all of whom eulogized the mountain’s inspirational scenery through painting and poetry creating a rich body of art and literature of global significance 64 temples were constructed on the mountain the monk Pumen came to Huangshan and built the Fahai Meditation Temple By the Ming Dynasty (around the16th century) depictions of Mount Huangshan had become a favourite theme of Chinese landscape painters establishing the influential Shanshui (“Mountain and Water”) school of landscape painting Showcasing the interaction of man and nature in this highly scenic setting has inspired generations of Chinese artists and writers Criterion (vii): Mount Huangshan is renowned for its magnificent natural scenery which includes massive granitic boulders and ancient pine trees which are often further enhanced by cloud and mist effects This dramatic landscape includes formations of natural stone pillars The property features numerous imposing peaks the famous Lianhua Peak (Lotus Flower Peak) Criterion (x): Mount Huangshan provides the habitat for a number of locally or nationally endemic plant species Its outstandingly rich flora contains one-third of China's bryophytes (mosses and liverworts) and over half of its pteridophytes (ferns)  Species endemic to Huangshan include 13 species of pteridophytes and 6 species of higher plants with many other species endemic to the region or to China This exceptional flora is complemented by an important vertebrate fauna of over 300 species A total of 13 species are under state protection including the Clouded Leopard Neofelis nebulosa (VU) and the Oriental Stork Ciconia boyciana (EN) All the elements that embody the values of Mount Huangshan are present within the boundaries of the inscribed property and its designated buffer zone It is a highly scenic natural area showing good evidence of glaciation The ancient temples (of which there are the remains of more than 20) the rock inscriptions and the pathways to them and to scenic viewpoints are also intact and well-maintained most of whom are staff and their dependants A policy is in force to reduce these numbers as well as the accompanying buildings as opportunities arise The imposing scenery of Mount Huangshan has inspired some of the most outstanding creations of Chinese painting and poetry A legend from the Tang Dynasty dated from the year 747 describes the mountain as the place of discovery of the long-sought elixir of immortality This gave to Mount Huangshan its name and assured its place in Chinese history fascinated by the landscape of mountains emerging from a sea of clouds During the Ming Dynasty (from around the16th century) this landscape inspired the Shanshui (“Mountain and Water”) school of painting whose masters included the artists Jian Jiang The most famous of all was Shi Tao whose essay “Comments on the paintings of the monk Bitter Pumpkin” is one of the most renowned works of Chinese literature It is from these works of art and literature that the authenticity of Mount Huangshan can best be understood; the place of inspiration for some of the world’s greatest cultural achievements Mount Huangshan World Heritage property is a National Park protected under the laws of China These include:  the Law on the Protection of Cultural Relics (1982) the Law on the Management of Scenic and Historic Interest Areas (1985) and the Law on the Protection of Wildlife (1988) conservation and management of the property have been strengthened by the establishment of the Management Committee of Huangshan National Park directly under the authority of Huangshan Municipality A special fund has been set up to assure adequate financial resources are available to monitor and manage the property to the highest international standards A Master Plan for the property is currently under implementation Objectives of this plan are to balance conservation of the property with tourism promotion to ensure the safeguarding of the scenic area within a framework of sustainable development for the local community and to raise conservation management standards by “digitizing and humanizing” the property’s management regime in order to preserve effectively the artistic cultural and environmental heritage value of Mount Huangshan The pressure of visitors is the most obvious factor affecting the property Mount Huangshan is one of the most popular scenic landscapes in China with annual visitation at 2.74 million and increasing at 8.96% per annum Other threats to the property include pine wood nematode pests; storm damage to trees littering); and water shortages which increase fire hazards Rocky Mountain National Park's 415 square miles (265,807 acres) encompasses a spectacular range of mountain environments From meadows found in the montane life zone to glistening alpine lakes and up to the towering mountain peaks there is something for everyone to discover Along the way explore over 300 miles of hiking trails and incredible wildlife viewing Planning to visit Rocky from late October through early June Be prepared for snow and winter conditions at higher elevations Timed Entry Reservations will be needed to enter RMNP beginning on Friday Discover what different park entrance fee and pass options are available Learn about road conditions and seasonal updates Planning to visit Rocky between late May and early September Learn all about planning for a summer trip to the park Click here for weather forecasts and other information Learn about different activities to enjoy in the snow Conditions can vary based on where you are in the park Click here for RMNP's latest Trail Conditions Report Learn about Camping in Rocky Mountain National Park Learn all about planning for a wilderness overnight backpacking trip The Kawuneeche Valley Restoration Collaborative brings together agencies and organizations focused on restoration of the Kawuneeche Valley Learn about Rocky's Long-Range Visitor Day Use Access Plan Moraine Park Campground & Headquarters Utility Project is underway Download the NPS app to navigate the parks on the go we are celebrating the 67% of our territory that lies within the mountains and highlighting the imposing Andes that accompanies almost all of our landscapes Then Chile is your ultimate destination: high snow-capped peaks and craters are some of the attractions that adventure sport lovers will find here among the highest summits of each of Chile's regions Parinacota Volcano - "place of flamingos" in Aymara - is the highest mountain in the region It forms part of the snow-capped Payachatas chain inside the Lauca National Park the volcanoes located in the Lauca National Park are the tombs gifted by nature to an Inca princess and prince which today bear the name of Parinacota and Pomerape The most recent volcanic activity is thought to have taken place around 1800 consistent with that which is told in Aymara legend Due to its height and low technical difficulty it is probably the most-climbed mountain in the area which means "devil's chair" in the Aymara language is a small mountain range of volcanic origin located on the Chile-Bolivia border Considered a sacred mountain or "mallku" in Andean culture dominating all the other peaks in the area It astonishes visitors with a small glacier tongue on its south-eastern face considered the southernmost glacier discovered in the altiplano (highlands) which means "hot water" in the Aymara language is located between Salta Province and the Antofagasta Region Despite being the third highest mountain in Chile with beautiful surroundings and small streams that flow between wetlands and grasslands in ravines replete with guanacos it is rarely visited due to difficult access and the existence of minefields in the sector There are currently two ascent routes in Chile: the northern route allows you to reach 4600m by vehicle while the southern route allows you to reach about 5000m it is necessary to cross large snowfields with hard snow; it is therefore recommended that you bring crampons and an ice axe east of Copiapó and straddling Catamarca Province on the Argentine side the Ojos del Salado Volcano stands out as the most impressive summit among the area's Andean peaks It holds several Chilean and world records: it is the highest volcano in the world; the second highest peak in America; the highest mountain in the Chilean Andes; and the second highest in the Argentine Andes Because of its location to the south of the Atacama Desert in the middle of the South American altiplano and accompanied by the snow and glaciers that crown the peaks of the Andes' most arid desert area As well as being the highest mountain in the Coquimbo Region Nevado de Olivares is the fourth highest in Argentina's San Juan Province after Nevado Olivares Central or La Majadita It is a "six-thousander" that is little-publicized due to difficulty of access and the lack of water in possible camps The normal route through Argentina begins next to the route to Paso Aguas Negras at the entrance to the San Lorenzo ravine at about 4100m altitude while the normal route through Chile beings past La Laguna reservoir at about 3400m; the approach is therefore longer through Chile In addition to the dryness of the mountain on the Chilean side this means that it receives very few visits from our country Juncal is a huge snow-capped mountain that occupies an important position in the central mountain range near Santiago It is the point of communion for large glacial systems that spread out from its four summits in different directions boasting snow that is unmatched among its neighbors especially those located in the central Chilean Andes have a northern slope as snowy and steep as Nevado Juncal It is therefore a unique case that has drawn the attention of glaciologists from around the world who have traveled to investigate it in detail "hill where the river of gold is born" and "observatory of the condors" are some of the interpretations of its name in the Huarpe It is the highest mountain in the Andes south of Aconcagua and dominates its surroundings with its enormous size and distinctive cone surpassing all neighboring peaks by many meters This volcano is a serious challenge for mountaineers seeking high-altitude experience isolated and technically simple "six-thousander" that is as hard as Aconcagua Many mountaineers who have ascended a mountain in the Cajón del Maipo area have probably been struck by the large a strange mountain that has been rarely visited in recent times due to access restriction policies Despite being the highest mountain in the sector it does not have a clearly identifiable summit but rather what appears to be a large glacial mass that is almost flat on top with four main peaks one in Argentina and another that straddles both countries the volcano complex of Planchón-Peteroa-Azufre constitutes one of the most attractive mountain phenomena of the central Andes which provide the source of important rivers which merges with the Teno River at Los Queñes and part of the upper Colorado River basin On the Argentine side is the Valenzuela River which turns into the Rio Grande further down Peteroa is a flat volcano of approximately 3600m It is located between the Planchón Volcano to the north and the Azufre Volcano to the south A set of craters awaits the mountaineer at the summit instead of the classic volcanic cone that Peteroa once had and its neighbor Azufre still maintains This volcano rises in the central zone of the Chilean Andes as well as its two large neighbors: Nuevo Volcano (3186m) and Viejo Volcano (3122m) It is home to several glaciers that give it its name the most characteristic being those that hang down to the southeast and southwest the southwest glacier has been reduced to a small mass of ice that descends from the summit to approximately 2500m in the direction of the Shangri La Valley there is a huge volcanic slag in the middle of a beautiful native forest containing lenga beech Because it is the most accessible of the region's glaciers it is used for practice by climbers from Concepción Chillán and other towns in the eighth region The Sierra Velluda is located east of the city of Los Angeles with an extraordinary height that dominates its surroundings It can be seen from Victoria in the south to Chillán in the north The mountain has numerous glaciers of considerable importance Tilly made the first ascent to the main summit of the Sierra Velluda (north peak Kroessig complains of not having encountered the difficulties they expected for a mountain with the fame that the Sierra Velluda had at the time is to the southern cordillera what Aconcagua is to the central cordillera: both surpass their neighbors by more than a thousand meters and impose themselves on the horizon like no other Some Argentine poets from Junín say that they glimpsed both oceans from its extinct crater This fantastic claim has still not been corroborated; however Lanín certainly dominates the surrounding area for more than 150km Mapuche legend had it that evil spirits lived at the summit of the volcano and killed those who dared to climb it Lanín also comes from the first-person plural of the verb "we sink" (in the ashes of volcanoes or in the snow) It is not known when the volcano last erupted but Lanín certainly scared many generations of Mapuche in past times The volcano's original name is Quitralpillán which means "dwelling of the ancestors with fire" in Mapudungun Villarrica is considered to be one of the most active volcanoes on the continent and its smoke can be seen from miles away during the day the fascinating reflection of the incandescent lava at its summit can be observed from great distances There are some who claim that the volcano was climbed by the Mapuche many centuries ago this hypothesis is unlikely considering the deep religious significance of the volcano as the sacred dwelling of their ancestors the Mapuche people respect the volcano and continue to dedicate rituals to it A lot of tourists currently visit the volcano's crater to observe the explosions of incandescent magma that occur at regular intervals it is possible to descend from the edge of the crater on skis or snowboards; the descent with the lake as a backdrop is amazing Incredible too are the ancient Dombey's beech and araucaria (monkey puzzle) trees in the forests surrounding the volcano covered by seven glaciers that spread out along its slopes until falling violently off of cliff faces; its height which makes it by far the highest peak in the surrounding area more than 100km to the north; its three regal-looking peaks; the gigantic cracks that cross its glaciers and are always a threat to mountaineers; and the remarkable environment in which it is located surrounded by spectacular lakes and symmetrical volcanoes All of this means that Tronador is a mountain that is difficult to forget for anyone who has gazed upon it Tronador is located to the east of Todos los Santos Lake it has three clearly distinguishable summits: the main summit lies on the border and is shared by the two countries; the Chilean summit Patagonia is home to some of the most attractive terrain in the world for exploratory mountaineering as there are still many mountains awaiting their first ascent An exception is the great Monte San Valentín considered the highest peak of the Patagonian Andes San Valentín is located at the northern limit of the Northern Patagonian Ice Field It is surrounded to the north by the Circo Glacier to the east by the San Valentín glacier and Cerro Cuerno de Plata to the west by the San Rafael Glacier and Cerro Pirámide; and to the south by Cierro Fiero and the glacial extension of the Northern Patagonian Ice Field Located in the Aysén del General Carlos Ibáñez del Campo Region within the Laguna de San Rafael National Park the Northern Patagonian Ice Field is an area of continental ice located entirely in Chilean territory and it has a length of approximately 120km and a width of 50km It is delimited to the north by the Tranquilo Bayo and Exploradores rivers; to the east and south by General Carrera Lake and the course of the Baker River; and to the west by the Pacific Ocean the Ofqui Isthmus and the Baker River Delta the Lautaro Volcano is not only the highest peak in the Magallanes Region but in the entire Southern Patagonian Ice Field This active volcano is part of the Pío XI cordon It is located in the Bernardo O'Higgins National Park northwest of the Cuatro Glaciares plateau from which the Viedma northeast of the Caupolicán plateau and south of the Todas las Madres plateau It last erupted in 1979 and there are abundant ash deposits on the surrounding glaciers (O'Higgins and Chico) which is why it is considered an active volcano For more information: AndesHandbook Meet "Chiri-Chan", Chile's mascot for Expo Osaka 2025 Global Cherry Summit 2025: Chilean cherry season is marked by an increase in shipments Chile-Brazil: 180 years of cooperation and a renewed economic agenda Chile projects itself in Asia with strategic presence in Expo Osaka 2025 one of the most pleasant urban parks in the city of Lisbon The project includes new leisure and recreational areas and equipment and the extension of pedestrian and cycling paths One of the most pleasant urban parks in the city of Lisbon is going to grow The promised construction of the second phase of the Mountain Valley Urban Parkin Areeiro which with this expansion will grow until it is very close to the Bela Vista Metro station The first works involve the removal of the debris that over the years has been accumulating on the slopes of that valley and the opening of new paths which currently occupies parts of the territories of the parishes of Areeiro and Marvila The expansion will complete the park with a second kioska lane intended for the sportive use of the bicyclean area of urban agriculture a large lawn for different sporting activities There will also be an extension of pedestrian and bicycle paths making it possible to reach areas that are currently inaccessible safely by these means The work is expected to last one year and is accompanied by one year of maintenance; will cost 3.38 million euros and is the responsibility of the company Decoverdi - Plantas e Jardins S.A.which won the public tender launched later in 2020 The second phase of the Mountain Valley Urban Park will follow the philosophy of the existing park: will be a space where Nature will be left in its most natural state possibleThis will promote the self-regulation of the ecosystem thus providing the city with a large urban park the city's recycled water network will be used the intervention will privilege the use of dryland biodiverse grassland and native species increasing the success of the vegetation installation and reducing maintenance costs and existing trees in good phytosanitary conditions and compatible with the program will be maintained (namely olive and fruit trees) The clearing area covered with grass will have a high load capacity in order to ensure an informal recreational use and stay and at the same time can be used as a recreational field The Mountain Valley Urban Park will be bordered to the south by the Estrada de Chelas/Largo de Chelaslinking to the old Convent of São Felix and São Adriãoof high heritage and historical value and also with the Santo Condestável Avenuewhere the designated Swiss Palace which today can be taken from both Alvalade and Areeiro will end at Avenida da Ucrânia and will assume different configurations along the park from a bidirectional design to areas shared with pedestrians It will be possible to use this green corridor to walk or cycle to Bela Vista or Chelas from Areeiro or Alvalade Remember that the Vale da Montanha Urban Park is directly connected to two other urban parks where festivals like Rock in Rio take place The first phase of the Mountain Valley Urban Park was completed in 2017 The work now underway should be completed by the summer of 2024 MB Way: 933 140 217 (indicar “LPP”) Ou clica aqui Podes escrever-nos para [email protected] O LPP / Lisbon For People é um jornal local dedicado à cidade e à área metropolitana de Lisboa editado de forma totalmente independente e sem fins lucrativos ' + scriptOptions._localizedStrings.webview_notification_text + ' " + scriptOptions._localizedStrings.redirect_overlay_title + " " + scriptOptions._localizedStrings.redirect_overlay_text + " peter schulz was a professor at the Institute of Physics "Gleb Wataghin" (IFGW) at Unicamp for 20 years He is currently a professor at the Faculty of Applied Sciences (FCA) at Unicamp In addition to articles in specialized journals in Physics and Scientometrics he is dedicated to scientific dissemination and the study of aspects of interdisciplinarity He published the book “The crossroads of nanotechnology – innovation 2009) and was the curator of the exhibition “So far so close – telecommunications and society” My memory goes back to the nearest peak, as the plates displayed there were brought to Campinas and revealed in the basement of the Cosmic Ray Department building until the end of the 1980s.[YOU] noticed by all of us who walked around there The plates are still available for analysis after all it is a repository of “big data” only analog (thousands of developed films) which needed diligent trained people observing under a microscope square millimeter by square millimeter of those films Particle Physics in Chacaltaya was not limited to the now distant year of 1947 but lasted for decades until the mid-1990s in a collaboration between Brazil and Japan the physicist who proposed the theoretical existence of mesons was Hideku Yukawa who then he suggested this collaboration to Cesar Lattes Science arrived in Chacaltaya before César Lattes, through a meteorological station in 1942, and today, returning to its original vocation, it houses a Global Atmosphere Watch station, collecting data on climate change[IX]. These changes, by the way, led to the closure of the ski resort there[X] The diversification of science in Chacaltaya can be appreciated by the appearance of the name of this peak in the titles abstracts and keywords in articles indexed on the Web of Science platform which curiously does not record the article in Nature in 1947 only those that appeared from 1960 onwards but which today share the list with other topics: atmospheric meteorology researched for the column; but visiting it seems impossible at least on this mountain at an altitude of 5400 meters [I] Content kindly reviewed by Edmilson Manganote [II]https://www.unicamp.br/unicamp/ju/artigos/peter-schulz/cientistas-esses-desconhecidos [III]https://www.symmetrymagazine.org/article/the-legacy-of-cesar-lattes [IV]https://www.nature.com/articles/162168a0 [IN]http://www.comciencia.br/o-eclipse-de-1919-e-as-disputas-pela-ciencia/ [VI] These and other stories are in the special edition of Jornal da Unicamp: https://www.unicamp.br/unicamp_hoje/ju/marco2005/capa281.html [VII] http://www.fiumsa.edu.bo/ [VIII] Wilfredo was Guillermo Cabrera's doctoral advisor [IX]http://www.chacaltaya.edu.bo/ [X]https://www.snow-forecast.com/whiteroom/chacaltaya-bolivia-worlds-highest-ski-resort/ Access JU news on Unicamp’s social networks secexec@unicamp.br sediments available in this river and in its tributaries are essential for fauna and flora species distribution and richness and also for soil fertility of Amazon floodplains Monthly suspended sediment discharge (QSS) in South America rivers in tons per day The color scale presents values in a base-10 logarithmic scale 10 to the scale values power. Source: Fagundes et al. how do sediments get out of the mountains and reach the oceans The rain will detach the soil particle and from there the water flowing on the slopes will transport these sediment particles to the nearest water body which may be a river that will find another river the water will carry the particle until it reaches the oceans (or it will be deposited along the way Largest Amazon rivers; denudation rate: time in which the topsoil layer decreases; and solid discharge: amount of sediment transported by a river reach in a given period           The Andean region (a mountain chain in the South America western region) has the highest rate of soil denudation (time in which the topsoil layer decreases) This makes this region the main sediment source for the Amazon rivers; we can call it the yield zone The lowest slope areas (dark green) are primarily responsible for sediment transport; we can call them transport zones The flatter regions (light green) and the flooded areas are those where most of the sediment deposition occurs; we can call them deposition zones           The Solimões River and the Madeira River are the main sediment transporters About 50% of the sediment delivered to the Amazon River outlet comes from the Madeira River The Negro River (a river of black waters) has a high water discharge and transports less sediment than smaller rivers The Tapajós and Xingu rivers have clear water and           Most of the suspended sediments are trapped in the Amazon floodplains In the following figure we identified some of the major Amazon floodplains with yellow dots The suspended sediment concentration in rivers generally decreases after the floodplains having major implications in the maintenance and dynamics of local ecosystems The floodplains that retain most sediment are located close to the Andes and in the Central Amazon after the confluence of the Negro and Solimões rivers as river water discharge increases the sediments concentration tends to decrease due to sediment dilution Annual average suspended sediment amount deposited in the major Amazon floodplains The color of the rivers indicates the daily average concentration of suspended sediments (CSS) in its reach The thickness of the rivers indicates the river discharge (Q) the sediment path from the mountains to the oceans is long sediments are an important “food” for rivers and help to maintain ecosystems we intend to assess the impacts of human action and climate change on sediment transport Fagundes, H. D. O., Fan, F. M., Paiva, R. C. D., Siqueira, V. A., Buarque, D. C., Kornowski, L. W., … & Collischonn, W. (2021). Sediment flows in South America supported by daily hydrologic‐hydrodynamic modeling. Water Resources Research, 57(2), e2020WR027884. (Link) Fassoni-Andrade, A. C. & Paiva, R. (2019). “Mapping spatial-temporal sediment dynamics of river-floodplains in the Amazon.” Remote Sensing of Environment, 221: 94-107. (Link) Filizola, N., Guyot, J.-L., Wittmann, H., Martinez, J.-M., de, E., (2011). The Significance of Suspended Sediment Transport Determination on the Amazonian Hydrological Scenario. Sediment Transp. Aquat. Environ. (Link) Filizola, N., Guyot, J.L., 2011. Fluxo de sedimentos em suspensão nos rios da Amazônia. Rev. Bras. Geociências 41, 566–576. (Link) Latrubesse, E.M., Stevauc, J.C., Sinha, R., 2005. Tropical rivers. Geomorphology 70, 187–206. (Link) Hugo é Engenheiro Ambiental (UFES), mestre e doutorando em recursos hídricos e saneamento ambiental (UFRGS). Veja mais no Grupo de Pesquisa em Hidrologia de Grande Escala, Plataforma Lattes, ResearchGate and LinkedIn Let’s deep dive into the world of kickboxing, check out the match between Butterbean and Montanha Silva This fight was truly a clash of the titans with both fighters boasting ridiculous physiques that made for an unforgettable spectacle This was Butterbean, standing at about 180 cm (5’11”) and weighing around 168 kg (370 lbs) standing at an astonishing 210.82 cm (6’11”) tall and weighing in at 142 kg (312 lbs) Butterbean is a legendary figure in the combat sports world Known for his robust build and punching power Eric Esch has had a storied career in both boxing and kickboxing Brazil’s ‘The Amazon Goliath’ Montanha Silva is a giant of a man at nearly seven feet in height His towering height and massive frame made him a formidable opponent in the kickboxing arena The match between Eric Esch and Montanha Silva took place at K-1 Beast 2004 in Shizuoka Despite the American’s powerful punches Montanha Silva’s size and reach proved too much and he won the fight by unanimous decision After this match, Eric Esch continued to fight in various disciplines, including MMA and boxing Butterbean’s career has been marked by his charismatic personality and his ability to entertain crowds with his aggressive fighting style Montanha Silva competed in various kickboxing matches and professional wrestling Timothy Wheaton is a combat sports writer who covers MMA He has been an avid follower of these sports since 2005 Tim also works with a host of other media sites such as Calf Kick Sports Tim is the authority on kickboxing and an MMA journalist who has covered K-1