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is a common cause of furuncular myiasis in dogs in Latin America
presented as an erythematous nodule that causes pruritus and pain
Typical treatment consists of sedation for removal of larvae by surgical incision or manual pressure
Medications to kill the larva before its extraction can reduce inflammation and discomfort and provide a less traumatic larval removal
Isoxazolines are broad-spectrum ectoparasiticides with larvicidal activity previously reported in the treatment of screwworm myiasis in companion animals
The aim of this study was to evaluate the effectiveness of sarolaner as part of the clinical management of furuncular myiasis in dogs caused by D
Ten short-haired mixed breed dogs naturally infested with D
Clinical diagnosis was achieved by observation of skin nodules and visualization of larval motility through the lesion orifice
Sarolaner was administered at manufacturer recommended dose for fleas and ticks
Lesions were reexamined 24 h post-treatment and assessed for viability of larvae
Larvae were removed by digital compression and identified as D
hominis larvae were retrieved from ten dogs
demonstrating 100% larvicidal efficacy of sarolaner
Skin lesions were healed 30 days post-treatment and new lesions were not observed
Sarolaner seems to be effective as larvicidal treatment for dogs with furuncular myiasis
reducing discomfort caused by the presence of the larva in the skin and facilitating its safe removal
The objective of the present study was to evaluate the effectiveness of sarolaner as part of the clinical management of furuncular myiasis in dogs naturally infested with D
All dogs were examined one more time 30 days after sarolaner administration to follow up on the initially diagnosed lesions and assess for the potential presence of new ones
The number of furuncular myiasis lesions with a single larva ranged from 3 to 16 in the enrolled dogs. Signalment, sarolaner administered dose, number of lesions and affected body areas are presented in Table 1
The areas of the body presenting with furuncular myiasis varied in the affected dogs
The largest number of nodules was observed on the lateral thorax bilaterally (46/75; 61.4%) followed by the top of the head (14/75; 18.7%) and base of the ears (7/75; 9.4%)
hominis larvae were retrieved from all 10 dogs
No adverse events associated with the sarolaner treatment were noticed during the first 24 h post administration
Upon physical examination 30 days post-treatment with sarolaner
all previously observed furuncular myiasis lesions were healed and no new lesions were noticed in any of the dogs
The fact that all ten studied dogs were mixed breed dogs with a short hair coat further corroborates these observations
The body areas where the lesions are found
as well as geographic origin and/or travel history of the affected dog should always be considered along with thorough physical and dermatological examinations
hominis larvae infestation at a standard dose recommended for the treatment and control of fleas and ticks
Isoxazolines are a novel class of ectoparasiticides that has unique characteristics of rapid absorption
high margin of safety and broad-spectrum activity labeled for flea and tick treatment and prevention
Different drugs in this class are also used off label for the treatment of mange mites and myiasis
a 100% larvicidal efficacy of sarolaner was achieved within 24 h post-treatment
hominis larvae to be mechanically removed from all ten dogs by digital compression
The death of the larvae likely decreased the discomfort caused by their motility within the furuncular lesion and associated inflammation
the treatment also facilitated larval removal and the clinical management of the lesions
avoiding the need of sedation or a more invasive procedure on the skin
dogs were reexamined 30 days after sarolaner administration
and not only all previously diagnosed lesions were healed
It is plausible that the monthly use of sarolaner for flea and tick prevention may also provide protection against the establishment of myiasis due to D
which are deposited on the hosts’ skin by phoretic dipterans
Oral administration of sarolaner at the dose recommended by the manufacturer seems to be effective for treating furuncular myiasis by D
reducing discomfort caused by the presence and movement of the larvae within the skin and facilitating removal of larvae
All data obtained in this study are included in this published article
Universidade Federal Rural do Rio de Janeiro
Furuncular myiasis caused by the human bot-fly Dermatobia hominis in a domestic cat from Brazil
First report of furuncular myiasis in a domestic dog caused by Dermatobia hominis (Linnaeus
Zhou X, Hohman AE, Hsu W. Current review of isoxazoline ectoparasiticides used in veterinary medicine. J Vet Pharmacol Ther. 2021. https://doi.org/10.1111/jvp.12959
Efficacy of sarolaner on the treatment of myiasis caused by Cochliomyia hominivorax (Diptera: Calliphoridae) in dogs
Chrysomya bezziana (Diptera: Calliphoridae) infestation in two Malaysian cats treated with oral lotilaner
Efficacy of afoxolaner (NexGard®) on the treatment of myiasis caused by the New World screwworm fly Cochliomyia hominivorax (Diptera: Calliphoridae) in naturally infested dogs
Cutaneous myiasis: a review of the common types of myiasis
Dermatobia hominis in a dog imported from Brazil to Romania
Botfly myiasis: case report and brief review
Inquérito sobre os casos de miíase por Dermatobia hominis em cães da zona sul do município do Rio de Janeiro no ano de 2000
Myiasis caused by the new word screwworm fly Cochliomyia hominivorax (Diptera: Calliphoridae) in cats from Brazil: report of five cases
Efficacy of spinosad on the treatment of myiasis caused by Cochliomyia hominivorax (Diptera: Calliphoridae) in dogs
Campos DR, Assis RCP, Chaves JKO, Almeida GPS, Lima EAS, Intrieri JM, et al. Furuncular myiasis caused by Dermatobia hominis in five cats and efficacy of topical fluralaner for its treatment. Vet Dermatol. 2021. https://doi.org/10.1111/vde.12998
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We thank Zoetis Brazil for covering the publication fees for the article
This study was funded by Coordenação de Aperfeiçoamento de Pessoal de Nível Superior—Brasil (CAPES)—Finance Code 001
Federal Rural University of Rio de Janeiro
Department of Veterinary Clinical Medicine
University of Illinois at Urbana-Champaign
College of Veterinary Medicine and Biomedical Sciences
Department of Veterinary Medicine and Surgery
PAA participated in the experimental design
preparation of the text and contributed to the corrections of the manuscript
RCM participated in the execution and experimental design
JIF participated in the coordination of the study
GGV and CPS contributed with the review and helped with the writing of the manuscript
All authors read and approved the final manuscript
The study was approved and conducted in accordance with the institutional animal care and use committee (number 2165240619 CEUA/UFFRJ)
Zoetis Brazil is the manufacturer and distributor of Simparic™
Zoetis Brazil covered the publication fees
but the authors declare that the sponsor had no role on this study and its conclusions or on the decision to publish this manuscript
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations
unless otherwise stated in a credit line to the data
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DOI: https://doi.org/10.1186/s13071-021-04910-3
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Four young players and a coach will arrive this Thursday and will spend a year at Perólas Negras soccer academy
They were living in the Zaatari refugee camp
São Paulo – Five Syrian refugees living in Jordan will arrive in Brazil this Tuesday (28) to practice and play in Perólas Negras, soccer team and school in the city of Paty do Alferes, Rio de Janeiro. The team was created by NGO Viva Rio
we try to place them in the market through soccer
in the sport field or not,” said the marketing director of Viva Rio
The group of Syrians includes four young players – Qais
“We went to Jordan and selected them at the Zaatari refugee camp
The executive describes Pérolas Negras as a “world team of refugees.” In the team
is registered at the federation and compete in regular tournaments
the team already competed twice in Copa São Paulo de Futebol Júnior and won the championship of the C level (third level) of Campeonato Carioca (Rio de Janeiro state competition)
not only of the Arabs in the West and here in Brazil
but of the refugees in general,” said the executive
According to Brazil’s ambassador in Amman, Jordan, Francisco Luz, the Asian Football Development Project (AFDP)
organization chaired by Jordanian price Ali Bin Hussein
and the Jordan Football Association held a first player draft
selecting 150 among over 1,000 young Syrian refugees in the country
the staff of Viva Rio visited Jordan and chose the five people to come to Brazil
The Brazilian embassy in Amman held a ceremony to hand the visas to the young players and it was covered by the local press. The Jordanian newspaper Jordan Times
had a full coverage of the event last Monday (20)
Joining the Syrian players and coach and the ambassador
also attended the ceremony the project’s manager
The Gulf country has deposited its instrument of acceptance of the World Trade Organisation (WTO) Agreement on Fisheries Subsidies
which is aimed at curbing harmful subsidies that contribute to overfishing and promoting the sustainable management of global marine resources
The Brazil-Arab News Agency (ANBA) is the news website of the Arab Brazilian Chamber of Commerce
Its goal is to promote communication between Brazilians and Arabs
especially if they are made with the right intent
Rich in Love is about two people from two different spectrums of life who meet
and discover there is a spark between them
How will they retain the spark while trudging through the lies being told to keep the relationship afloat
This and more below make Rich in Love an interesting watch
Rich in Love introduces the viewers to Teto Trancoso from Paty do Alferes
He is the heir to his father’s agricultural empire
The boy is the epitome of a rich brat who has no clue about the amount of hard work that is being put in to make the company run
is the caretaker’s son and happens to be the only person who is honest with him
but Teto does not understand the concept of working his way up the hard way because
the Richie Rich life has been handed to him on a platter
Teto is more concerned about the birthday party he is throwing and the car he wants from his father
Paula is a hardworking doctoral resident intern with a local hospital in Rio de Janeiro
is keeping her around only because he likes her
Paula heads to Paty do Alferes for her best friend’s bachelorette party
Teto’s grand birthday party at Paty do Alfares sets the stage for the meet-cute between him and Paula
Paula comes across as an independent woman who loathes the idea of spending money lavishly
and Paula is the first one who does not care who Teto is
it is obvious to notice that Teto goes through a change of heart not just because of Paula but also because Igor instilled in him the idea of being with a person who will always challenge him and not just agree to everything he wants
he joins the apprenticeship program in Rio as Igor
and Igor would be presented as Teto so that the real Teto can slip through the program as someone else and prove himself to be the right person for the job of the junior executive
and he will have to play fair and smart when it comes to earning the position
But the lies he is concocting will catch up to him
In a bid to meet Paula in the city and ace the apprenticeship program
Teto ropes in Monique because she has been fired from his father’s company
The boy does not feel pity for her but rather offers her a fair deal
Asking Monique for help showcases the seriousness with which Teto is willing to work on himself from scratch
Monique and Paula have been the only two women he’s met who did not try to sleep with him
and he wants to keep them around because he believes
Monique agrees to the deal because she has her sister and her sister’s child to take care of
and that’s why they begin helping each other out
Teto pursues Paula and introduces himself as the son of the caretaker of the rich Trancoso farmland
but to begin a relationship based on lies and question whether Paula is after his money is probably not the correct approach
He has balanced the act so far without much confusion
But his lie won’t last long because soon things will get out of control
is pursued by talent consultant Alana at the program
Without realizing the plan made and put into motion by Teto and Igor
she falls into the trap that Teto had set up
With all the lies that have been spread by Teto for his convenience
things go awry on the night of his meeting with investors
which happens to be the night of Paula’s graduation party
This was bound to happen because no matter how much one tries to get hold of the lies and pile them with other lies
This is what happened in Teto and Igor’s cases
Teto’s identity is revealed to Paula by her friend’s cousin
but what bothers her is that he does not feel comfortable enough to share his real identity with her
causing a rift between the two in the form of trust issues
Teto is the one who is announced as the winner of the coveted post
was expected to happen because Teto comes across as someone with business acumen
but he is not good at looking at the long-term repercussions of the plan he set in motion a month ago
He was supposed to give the car to Igor if the latter was selected
Though Alana is happy to know Igor is not Teto
but since Teto was announced as the winner as well
the car comes to Monique as per her deal with Teto
There was no written contract between anyone
and the four of them reached a dead end in their pursuit to come to an understanding
and it makes a profitable investment for all four of them
and the amount received from the sale will be invested in the business of growing organic tomatoes
The venture involved Monique’s neighborhood in a program to grow organic tomatoes on their roofs
and the residents would earn extra income from taking part in it
This idea encourages the upliftment of the community
This would also push the youngsters to experiment with their entrepreneurial skills
and Teto’s father is proud of his son for stepping away from his comfort zone and promoting organic produce
The ending of Rich in Love brings Paula back into Teto’s life
She has probably heard of his successful venture
and she is also proud of him for what he has managed to achieve
which is a sign of their coming back together
The film ends with the last shot of the roofs of the entire neighborhood filled with tomato gardens
Rich in Love is a Brazilian Netflix original streaming with subtitles
Teto and Paula are back with the second installment of Rich in Love
After all the deceit and drama that unfolded in Rich in Love
Teto and Paula finally reunited in the end
They are still together and madly in love with each other
But problems start in paradise when Paula decides to resume working as a volunteer doctor in the Amazon
Bidding goodbye to Paula was not easy for Teto
and he was ready to do whatever it took to keep her close
but business at “Teto Fresco” was not going too well
His father decided not to renew the contract between ‘Trancoso Tomatoes’ and ‘Teto Fresco.’ The co-op started by Teto
and with ‘Trancoso Tomatoes’ refusing to buy their product
and he asked his father to somehow convince Paula and her mentor
to set up their project in Paty do Alferes instead of the Amazon
Paula could sense that Teto was behind the proposal
Tawan wanted to focus on the patients who were dependent on them in the Amazon
offered to help their cause by connecting them with businessman Everaldo Coimbra
Coimbra worked at his father’s farm and used to be his right-hand man
had recently become the largest producer of tomatoes in the north of Brazil
Teto watched his dream crush before his eyes as Teo provided Dr
Tawan and Paula with sponsorship to continue their work
When Teo declared that he would not resume the contract his company had with ‘Teto Fresco,’ Teto tried to come up with a plan to save his co-op
Tomatoes were produced in abundance in the southeast
so Teto decided to take his business to the Amazon
The decision was partly to save the company but mostly to stay close to Paula
Teto arrived at Paula’s medical camp on her birthday in a decorated steamer boat
Paula struggled to put up with Teto’s overbearing nature
She wanted to focus on her work instead of dealing with her boyfriend’s insecurity and tantrums
When Paula left the settlement to visit another community
Teto decided it was the right time to chase her and propose to her
As Teto tried to find his way through the forest
Members from the indigenous community helped Teto recover
The accident allowed Teto to look beyond his selfish needs and focus on finding a solution that would help his business and benefit the indigenous community as well
When Everaldo Coimbra offered to buy Teto Fresco
He was not ready to let go of the business for money
selling the company was the next logical step
Teto requested that Igor and Monique give him a week to come up with a proposal that would help revive their business; if he failed
Teto’s plan was to create sustainable agroforestry by making a ‘Teto Fresco’ co-op in partnership with the Hipanaa community
Teto had to win the trust of the Hipanaa community
and only then could he start building the co-op
a member of the community who helped Teto heal from his injury
the community would not have to depend on working at the illegal mine
The money that the community would earn could help them fight for their land
he needed the approval of every leader that existed within the community
Teto had to first prove that he could become a part of the community
Wunin helped him understand how his negligence was affecting everyone around him
She taught him the importance of learning to live as a collective
Teto was a spoiled brat who never had to care about others’ opinions
but as he started to live within the community
he realized the importance of listening to others and working together
After proving that he was worthy of becoming a part of the community
and he was declared a member of the collective
After watching Teto evolve from a self-obsessed individual to someone who was ready to dedicate himself to the community
Their romantic moment under the waterfall was interrupted when they heard faint screams
They noticed Wunin there and watched the people working at the mine from a distance
Paula noticed that the men were adding mercury to the deposits they collected
and she realized that it was the reason why most of the people in the community were rapidly falling ill
Community members who worked at the illegal mines knew the reason behind the sudden sickness
but they were helpless and chose to remain silent.
Everaldo was not selling tomatoes for the price of gold; he was selling gold
The tomato business was simply a cover for the illegal mine
Everaldo planned on expanding the business
and he was bribing his way to get the regulations modified according to his interests
Teto’s partnership business idea was a threat to Everaldo
and that was the reason why he wanted to buy the company
Since Tawan was trying to raise awareness about the impact of mercury on the community
at least until the mine was regulated and under law
Tawan accepted the money offered by Everaldo
Wunin later revealed that their community member
was kidnapped by Everaldo’s men to force their community to move out of their land
They could either sacrifice their lives by staying
Igor and Monique were ready to accept Everaldo’s deal
but they wanted to wait for Teto’s approval
and Wunin climbed in and threatened Everaldo to ask his bodyguards not to react to the sudden hostage situation
so Paula discussed Everaldo’s illegal mining business to explain the ambush
The only way for Everaldo to escape the situation was by allowing Pawi to go free
Since Igor had introduced himself as Teto to win Everaldo’s trust
he asked Igor (who he thought was Teto) to somehow come to an understanding with Teto (who
Teto admitted that he was Teto and not Igor
but he did not understand the secret that Everaldo was talking about
Teto’s grandfather had a son out of wedlock
and Everaldo was the one who handed the baby over to the farm housekeepers to raise him
While Igor was not sure about Everaldo’s story
He always considered Igor to be his brother
and he was elated upon finding out that they were indeed related
but he refused to admit that he was at fault for investing in an illegal mine
Everaldo was convinced that someone someday would take advantage of the land
and he was not apologetic about the decisions he made
He pointed his gun at Teto and shot him for ruining his business
and he was brought to Hipanaa to be treated
Paula revealed that she knew about the bribery
Tawan showed Paula the video he had secretly shot during his conversation with Everaldo
He was not on Everaldo’s side; he simply wanted to show the world how corrupt Everaldo was
The video started to trend on social media platforms
Rich in Love comes to an end with the arrest of Everaldo five days after the release of the bribery video
Nine million dollars in cash were recovered from the operation
Alena and Monique were back at Paty do Alferas
The family gathered for Alena’s baby shower
they were all glad to be together as a family
Teodoro offered Igor to become the Vice President of the Trancoso company
Igor could not accept the offer because Alena wanted to continue working after giving birth
and he decided to look after their baby and focus on completing his college thesis
Teto asked Teo to consider Alena for the VP position
Teto announced Monique as the CEO of ‘Teto Fresco.’ After starting the partnership
‘Teto Fresco’ became a booming business
we find out that Teto was onto his next innovation after finding a sustainable way to keep ‘Teto Fresco’ afloat
she mentioned having had golden tomatoes as a child
Teto was fascinated by the idea of golden tomatoes
and he decided to travel to the border where Wunin grew up to find a way to grow them
Teto was successful in growing back the golden tomatoes
and finding solutions and innovations gave his life meaning
He intended on taking the golden tomatoes to Wunin and the community
and only if they agreed would he take the tomatoes around the globe
Paula realized that Teto was no longer the spoiled brat she once met
He found his identity without constantly relying on Paula to give his existence meaning
and she fell in love with him all over again
Rich in Love ends on a happy note with the reunion of Paula and Teto
and life turned out to be his best teacher.