The new site, which specializes in early-phase development and manufacturing services with a team of more than 80 employees, is set to strengthen Siegfried’s customer offering for drug substances in terms of capabilities and geographical coverage Siegfried intends to develop the site into a best-in-class hub for early-phase CDMO services for its global customer base including services for projects with highly potent APIs said: “Siegfried now offers an integrated range of services from early-stage development to commercial production of APIs through to the manufacturing of fully formulated drug products.” enable the company to provide comprehensive support to customers in the pre-clinical and clinical development and manufacturing of drug substances and further strengthen its drug substance pipeline The acquisition is financed from existing funds The outlook for 2024 and the mid-term financial targets remain unchanged CHEManager Spotlight is an exclusive event tailored for practitioners and decision-makers in the chemical industry This part of our event series delves into the latest trends and innovations in logistics to streamline your operations and drive efficiency CHEManager Innovation Pitch supports innovation in the chemistry and life sciences start-up scene and start-ups to present their companies to the industry In a five year period from 1990 through 1995 Maddy Tormoen was in the opinion of many observers the greatest woman duathlete in the world She won many races in the Coors Light Duathlon Series and after that many more Powerman races She punctuated her pro duathlon career with eight straight wins in the Powerman series and her second victory at the sport’s crown jewel at Powerman Zofingen in 1995 she collected $50,000 – the biggest prize purse in multisport to that point — $30,000 for the women’s title $10,000 for beating all the men in a gender handicap division and another $10,000 for winning the Powerman series title Tormoen also qualified three times for the U.S Olympic women’s marathon trials with a top finish of 30th place in a time of 2:41 in 1996 Unlike other woman champions at Powerman Zofingen like Erin Baker Tormoen never competed in the fast-growing and more popular sport of triathlon After spending two months trying to learn to swim competitively What few fans of the sport realized about Tormoen is that her success was somewhat of a miracle as she stoically endured dozens of operations for a myriad of leg ailments Like triathlon world champions Greg Welch and Emma Carney Tormoen has survived several near-fatal bouts of ventricular tachycardia with the aid of an implanted defibrillator she lives in Colorado Springs and works as a counselor with the Colorado Department of Corrections just outside Chicago until I was about 3 or 4 years old ST: Tell us something about your parents and siblings my father is living in the Minneapolis area and my mother lives near me in Colorado Springs None of my siblings pursued athletics to the extent I did however I had a younger sister who was a very good distance runner in high school She also ran one year in college and with little effort qualified for nationals One of my brothers was good at basketball Maddy: I came from a very large and complex family My parents divorced when I was in the 5th grade and my father eventually remarried We started living with my father and stepmother when I was in the 7th grade My father and stepmother eventually had three other foster children live with them who were my stepmother’s sisters’ children Maddy: I look very similar to my father’s mother so I guess I have a strong Norwegian heritage I would describe myself as fairly serious in my outlook and very determined You might say I persevere in the long haul Maddy: I was the fourth of six full siblings I cried a lot as a child and did not like attending preschool I had a neighbor boy who walked to school with me and I remember sticking my head in the bushes and crying as he tried to get me to go with him I was the athlete of my class; when I was young we moved to a small town in Wisconsin called Port Edwards and we lived in a large house on the Wisconsin River There were about 60 kids in my graduating class and engaged in three sports during the school year My freshman year I was a bit of a troublemaker but I turned it around again during my sophomore year ST: Any moments growing up that defined your character my parents divorced when I was in the fourth grade My mother struggled with schizophrenia during my upbringing; she was hospitalized when I was in the third grade for the first time Then she was hospitalized again when I was in the fifth grade and a couple of times after that Witnessing her struggle with her illness certainly impacted me as did not having her around much of the time my siblings and I did not have any consistent adults in the home This made us all very independent and we took on a parenting role for ourselves and each other at a young age I learned pretty young about some of the cruelties life can offer and I was therefore more serious and less light-hearted Maddy: I ran track and cross country in high school I qualified for state in the 440 yard dash once I think I qualified for the state meet in cross country one year as well I loved basketball and played guard and forward I earned the nickname Stormin’ Tormoen because I was so aggressive on defense I have a picture of me playing in high school where I look funny as I am so focused and have the eyes of a tiger Maddy: I attended Oregon State University initially I was paying for my own college so I dropped out I had a very bad experience in my first psychology class I signed up for what I was led to believe was a research project as part of my class requirement and the professor abused my mind He claimed to be one of the best hypnotists in the world and was what I would describe as obsessed with shamanism and the pursuit of power I was young and did not understand all of this until it was too late I moved away at the end of the term and worked in San Diego before returning to school a year later in Eugene Maddy: I rowed on the eight-woman crew at OSU one fall It was fun; I sat just behind the stroke in seat 7 so I was part of the stern pair I had to reinforce and support the pace set by the stern I enjoyed this seat and learned I can do well supporting someone else Maddy: While earning my master’s degree I started taking long trail runs It was a very reflective time in my life and long runs helped me sort through the things my mind was pondering I ran some local races in Eugene and I won a half marathon I thought that was pretty good given I was in Eugene so I started to train with Mike Manley and I qualified at the Houston Marathon for the Olympic Trials I ran the Trials but was having hamstring problems that plagued much of my career I had my first hamstring release operation in 1989 During that time I started to bike for rehab and after putting the two sports together I started duathlon ST: What were your best running performances Maddy: My best results were in the marathon but I think if I had tried to run in college I could have been a good miler and 5k runner 40 minutes and 23 seconds at Cleveland in 1996 where I placed 6th on a flat and fast course ST: What years did you qualify for the US Olympic marathon trials Maddy: I qualified in 1988 in Houston with 2:43.51 Then I qualified again in 1996 at the Disneyland Marathon and then ran 2:41:40 at the Trials where I finished 30th I qualified for the 2004 trials at the Houston Marathon where I placed 2nd with a time of 2:45.30 What do you remember about your first time in Switzerland Maddy: That was my first time out of the country and I did not get picked up at the airport by the race committee I was an elite athlete but no one was too worried about me at the time obviously I met some guys who took me to the basement of some building for a free meal for immigrants and I ate potatoes and gravy and green beans for lunch along with a bunch of old men who were all laughing at me Some guy I met in an alley wanted to marry me so he could become an American citizen I must have looked very lost walking around the city trying to figure out where I was supposed to be ST: What about your more successful outings at Zofingen Maddy: The first time I won I can hardly remember the screw that held my handlebars in place broke a few miles into the bike Murphy Reinschreiber just about died when he saw my handlebars after the race Erin Baker would have beaten me anyhow and I ended up second [9:53 behind Baker] ST: Tell us about your big payday at Zofingen in 1995 where you won $30,000 for first place and a $10,000 bonus for the gender handicap prize and I knew going into the race she would push me That year I felt a lot of pressure and had a lot riding on my shoulders I had returned to Oregon State University to confront the professor who had been so abusive and had filed some complaints and so forth during the two years prior so I was dealing with some difficult political issues in my personal life But I entered the race determined to win and did I actually earned $50,000 as I also won $10,000 for winning the Powerman series that year Maddy: I had numerous good running coaches over the years Mike Middlestadt and Dick Brown [Mary Decker Slaney’s coach in the early ‘80s] are several I recall I learned a lot from my running coaches that I was able to translate to training on the bike I coached myself during the last two years of my racing It worked out fine as I think this taught me to push hard at the front of a race with no one around I won every duathlon I did during the 1994-5 Powerman series Maddy: Traveling to so many places in the world and having success in sport helped me in other areas of my life I have had to face some difficult issues and it gave me confidence to confront those things that needed addressing and I continue to live my life in this manner I rarely say to myself that I can’t do something I am interested in doing Maddy: Earlier in my career it was Liz Downing Liz had dominated the sport for a long time so when I challenged her dominance it was of course considered a rivalry When I started to focus on the Powerwoman series after the Coors Light series ended my main rivals were often triathletes who showed up at Zofingen At one point Heather Fuhr raced a lot of Powerwoman races but I was able to beat her due to my bike leg I remember beating her in Japan; I could tell the male pros had been rooting for her I think they just wanted to see someone else win ST: Describe your simple enjoyment in running Maddy: I love the peace and quiet of running on trails I planned to compete in mountain races but was diagnosed with a heart ailment and had to slow down ST: You have had more than your share of injuries people did not realize how many injuries I had I had five left knee surgeries because I hit a hurdle in high school and my leg hyper-extended I raced my entire duathlon career with no ACL in my left knee I had three bilateral hamstring releases due to compartment syndrome; then eventually my piriformis muscle was released on both sides Apparently that is what I needed from the start I also had heel spurs and neuromas removed ST: Why did you continue after so many operations I simply enjoyed the process of getting back into shape after surgery This was when I would see significant improvement and payback for my effort I think some of my experiences have given me a rare determination to succeed when it would make more sense to fail when forced to face one of my greatest fears it was my refusal to give up that helped me persevere I accessed my survival instinct to the fullest because deep down I believed if I gave up I would fall into an abyss and no one would be there to catch me this tendency has caused me to fight back excessively ST: What did you do after you retired from pro duathlon Maddy: After I retired from duathlon in 1995 I continued to run but also returned to full-time work as a counselor but also had my ACL replaced and piriformis released In 2000 I had heart tests due to dizzy spells I experienced while training The doctor told me I was alright but the dizzy spells recurred and got worse In 2001 I was diagnosed with ventricular tachycardia which is when the large chambers of the heart begin to beat too quickly VT is life-threatening if not terminated rather quickly ST: Were you surprised you suffered ventricular tachycardia after you retired I actually had my first episode of ventricular tachycardia (VT) at the Duathlon National Championships in Santa Fe I just did not know what it was at the time I dropped out of the first run due to dizziness and blurred vision and the symptoms went away as fast as they occurred — after about 15 seconds but after I was diagnosed in 2001 I realized it had been VT that self-terminated ST: How many other episodes did you suffer through before diagnosis Maddy: In 1994 I was at O’Hare Airport in Chicago after returning from Europe with a 5-hour layover I went out to an empty parking lot to do a few running intervals and woke up lying on the cement after my third interval I thought I had simply fainted but in retrospect that was a bad episode of VT I was told I was lucky to have lived; I was alone so no one witnessed exactly what occurred I did not have any more episodes that I know of until 1998 just after winning the Garden of the Gods 10-mile run I went into VT that did not self-terminate My blood pressure dropped to 30/10 that day and I was unconscious by the time the ambulance arrived That was when the doctors realized I needed a defibrillator Maddy: My first defibrillator was not a cure-all 14 being inappropriate (my defibrillator shocked me when it did not need to) and 18 appropriate (the shock was to stop VT) But there is no doubt I would have died several times over if I did not have a defibrillator ST: How many operations have you had for VT Maddy: I have had a total of eight surgeries related to either implanting a defibrillator or removing old wires a procedure that destroys a small portion of heart tissue to disrupt the electrical short-circuit in the muscle causing VT Ablations work very well for atrial fibrillation which is when the small heart chambers beat erratically ST: What finally convinced you to quit competing at a professional level in running Maddy: I qualified for but did not run the Olympic Trials in the spring of 2004 as my ventricular tachycardia was occurring more frequently I had an ablation for the VT at the Mayo clinic in May of 2004 it made my VT worse and I got shocked a lot that summer I had another ablation in September of that year by the same doctor and was able to slowly get back into non-competitive exercise But for the first time in my life I was too afraid to compete again as I knew I would just get shocked if I tried ST: What was your emotional reaction to these repeated life threatening jolts Maddy: I was very sad to have to stop competing I still dream about Zofingen and duathlon Sometimes I wake up and realize how detailed my dreams are and how much I just want to go and be able to compete again I was very sad it had to end the way it did; I felt broken all over again And that was after working hard to heal from other deep wounds ST: Did you talk to Greg Welch about ventricular tachycardia Maddy: Greg and I talked a couple of times over the phone We have both been through a lot with our hearts I let him know I would be dead without my defibrillator when he was making the decision about having one implanted I would have enjoyed talking to him more but we all deal with our issues in our own way and I got the sense he needed space to handle his heart the way he needed to I am really glad to hear he is doing well ST: Do I remember correctly that you once said you wanted to make sure that you had used up every mile in your body before you died Maddy: I probably did make a comment like that and I guess I’m living up to those words I’m sure my body and mind will be entirely expired when I pass on That principle helped me achieve a lot in sports and now I try to apply it to other goals I want to have an impact on the world; I enjoy looking under the surface of things to determine what else might be going on that others are ignoring or have missed ST: What work did you pursue after you were through with sports Maddy: I started working full-time in the prison system in Colorado counseling sex offenders and then inmates at the psychiatric prison I eventually worked with incarcerated women and then with boys committed to the Division of Youth Corrections This is what I still do; I have always worked in the mental health arena Maddy: We have programs to help teenage boys build healthy strategies to have fun and belong with the hope of getting them out of gang-associated criminal activity and/or substance abuse Kids come to us with very serious addictions and criminal activity in their background They have often experienced significant trauma and abandonment and see little hope for a different future I see my work as an opportunity to support youth during a difficult time in their lives and to help them make lifestyle changes they want to make ST: How satisfying has it been to work as a counselor I have always wanted to give back; my mother taught me to value giving through her volunteer work she is doing great and has been stable for years She assists boys in youth corrections by tutoring them in math and recently received an award for all her volunteer effort ST: What did you buy with your big $50,000 payday I supported myself after moving out of the house at 18 so I learned to value money and understood responsibility at a young age Instead I built a barn and lived out there for a couple of years until I decided to move to Colorado Springs ST: Has your ventricular tachycardia been tamed But last summer I got 12 very painful shocks that were inappropriate a defibrillator wire which was recalled years ago The Sprint Fidelis Lead breaks more frequently than other wires and when a defibrillator wire breaks it can result in the defibrillator not delivering a shock when it should My Sprint Fidelis Lead broke in May of 2013 and unfortunately the alarm did not go off to notify me of the broken wire Medtronic developed software called the Lead Integrity Alert system for defibrillators and if programmed correctly it can warn you with an alarm that your wire is broken My software was not programmed correctly so when my wire broke in May the alarm did not sound Two months later the wire got so bad my defibrillator just started shocking me Maddy:I am very lucky to be able to run and ride my mountain bike at a comfortable pace but my heart has been pretty stable for several years and my medication helps keep me out of VT ST: What is the advanced degree you are pursuing now Maddy: I am working on my dissertation and I will graduate with a PsyD in Organizational Leadership My focus is on iatrogenic outcomes in psychotherapy which is a fancy way of saying I am investigating the literature surrounding harmful therapeutic outcomes exploitation and oversight within the profession I hope to add some qualitative research to the area of study by interviewing people who have had negative counseling experiences It is a fascinating topic and one that needs further attention and of course my personal experiences have given me insight that many others may not have ST: How satisfying has it been to build that barn in Pueblo and to work on your house and garden in Colorado Springs Maddy: Colorado Springs is a beautiful place to live and the downtown area is great It was an experience I will never forget and when I decided to sell my land I remember driving out there one day It occurred to me that I was saying good-bye I had to pull my car over to the side of the road and cry for a long time I left a part of my soul out there; I have not returned since I sold it as I prefer to remember it as it was I moved rocks from my land to my home here in Colorado Springs and built a rock garden in my front yard Now I don’t know if I will ever be able to sell my home I live in now © Slowtwitch - Built with Federated Computer we and our partners use technologies like cookies to store and/or access device information Consenting to these technologies will allow us and our partners to process personal data such as browsing behavior or unique IDs on this site and show (non-) personalized ads may adversely affect certain features and functions Click below to consent to the above or make granular choices. Your choices will be applied to this site only. You can change your settings at any time or by clicking on the manage consent button at the bottom of the screen To read Meredith Dolhare’s long list of athletic triumphs, it’s tempting to ask if there’s anything she can’t do. After transferring to join the Vanderbilt women’s tennis team in 1993 following a freshman stint at perennially top-ranked UCLA, Dolhare (along with then-new Head Coach Geoff Macdonald) helped lift the program from a ranking in the mid-70s to the top 10 nationally Dolhare completed several marathons and 12 Ironman triathlons before setting her sights on far more arduous adventures In 2013 she finished third in the Badwater Ultramarathon—a 135-mile race in 120-plus-degree heat that features a grueling climb from California’s Death Valley (279 feet below sea level) to the trailhead of Mount Whitney (8,360 feet) Four months later she became the sixth woman ever to complete the Death Valley Cup which combines the Badwater run and the Furnace Creek 508-mile bicycle race Among her proudest accomplishments is a fifth-place finish in the Brazil 135 an ultramarathon that winds through the jungles of Camino da Fe in South America and includes 30,000 feet of ascent and 28,000 feet of descent “That one was hard because I’d had reconstructive surgery on my spine six months earlier,” Dolhare says She also finished second among women in the Ultraman United Kingdom a three-day endurance race that includes a 6.2-mile swim underneath Dolhare’s seemingly endless string of athletic-endurance accomplishments lurks a darker history of battling substance abuse and depression problems that stemmed from the trauma of being raped by a peer in high school So getting to the finish line and crossing it—it’s like you’re shedding something “Finishing a race is the most amazing feeling Partly through her newfound love of endurance racing Dolhare realized she wasn’t the only person who had experienced bad times but I came to realize somebody always has it worse.” a nonprofit organization that aids homeless men and women “The homeless aren’t cute and cuddly,” she says Dolhare and her team use physical fitness as a method to teach the homeless community life lessons Each session includes a run followed by a workshop that focuses on anger management “We aren’t just handing them a meal and walking away,” says Dolhare whose RunningWorks organization now operates five programs that serve a minimum of 60 participants each week “We are trying to teach them a way of life We are teaching them how to fish—not just giving them a fish.” Dolhare credits her time at Vanderbilt for preparing her for this chapter in her life and is the main reason she continues to be involved with the university through volunteering and philanthropy “Transferring to Vanderbilt was one of the best decisions I have yet to make in my life,” she says “My human and organizational development major prepared me for the challenges I face every day not only in running a nonprofit but also in interacting with those I consider part of my family of choice within my own organization It is an easy segue for me to stay involved with an institution that has given me so much.” Nashville, Tennessee 37240 615-322-7311 • Contact Us Vanderbilt University’s Online Privacy Notice Medievalists.net A remarkable medieval coin hoard has been discovered in southwestern Germany Around 1,600 coins dating to the 14th century were found in the village of Glottertal Claus Völker made the discovery while doing pipe laying work near the village’s swimming pool He spotted some “small metal plates’  and contacted representatives of the State Office for Monument Preservation (LAD) of Stuttgart Regional Council the archaeologists found about 1000 coins in the trench where the pipe was being laid down The LAD followed up the discovery by commissioning three metal detectorists to search the surrounding area experts began assessing the significance of the hoard “These are mainly coins from the Breisach which were minted around 1320,” explained Andreas Haasis-Berner He further noted that some coins originated from Basel Haasis-Berner also highlighted the historical importance of the find: “The evaluation of this coin hoard will enable us to make statements about the circulation of coins in Breisgau but also the mining in Glottertal.” He added an intriguing perspective on the hoard’s value at the time: “You could have bought about 150 sheep with the coins.” Top Image: Courtesy State Office for Monument Preservation in the Stuttgart Regional Council We've created a Patreon for Medievalists.net as we want to transition to a more community-funded model We aim to be the leading content provider about all things medieval podcast and Youtube page offers news and resources about the Middle Ages We hope that are our audience wants to support us so that we can further develop our podcast and remove the advertising on our platforms This will also allow our fans to get more involved in what content we do produce Member Login Siegfried Bilfinger maintains the production facilities for Siegfried at its location in Zofingen Bilfinger has been providing maintenance services for its Swiss client since 2010. Specialists make use of the Bilfinger app "BMC@work" for maintenance services allowing them to receive paperless tasks or to revise material needs online Bilfinger also provides support for repairs maintenance and inspections of the production facilities Bilfinger employees also manage the auxiliary and operating materials warehouse for Siegfried manage reception and are involved in plant protection provided by fire officers they oversee plant expansions and conversions A total of 55 Bilfinger employees at the Zofingen site are involved in providing industrial services Learn more (German) Receive our weekly Newsletterand set tailored daily news alerts Three new Monforts finishing ranges were installed in record time for a Swiss mill to mark its 185th anniversary Interiors has installed two new energy-saving six-chamber Montex stenters as well as a Monfortex compressive shrinkage range to replace the machinery damaged during the heavy storms that broke in July 2017 Particularly badly affected was the town of Zofingen in the canton of Aargau the most fierce hail storm I’ve ever seen This was enough to close all of the local roads and then the rain started and just didn’t stop – and the flooding and landslides began,” recalled the company’s plant manager Frank Katzenstein the Bethge plant was in the direct line of a 1.6-metre-high wave which thundered down onto the town when a dam above it finally burst its banks “It was unbelievable in its ferocity,” said Mr Katzenstein “It crashed right through the steel doors of the plant and completely engulfed our machines More than 450 rescue workers were mobilised to deal with the chaos in Zofingen the railway station underwater and the motorway around the town closed in both directions for many hours although a number of people were taken to hospital but the freak storm had caused millions of francs worth of damage with the Bethge plant taking the brunt of it The following week a crisis meeting was held by the directors of the family-owned company and it became clear that its finishing lines – including the existing Monforts stenter and shrinkage range – would have to be completely replaced “It really looked like the business was finished unless we could resume operations in a very limited amount of time,” said Mr Katzenstein “For many years we have specialised in the finishing of woven textiles for third party brands and distributors These are destined for the home and hotel tableware and bedding markets in Switzerland “Hospital linen is another key end-use sector for our fabrics and as one of the few remaining textile finishing operations in Switzerland – where both costs and environmental standards are extremely high – our just-in-time delivery and quality guarantees have been crucial and the company’s manufacturing and installation teams were able to pull out all the stops for us.” Bethge opted to order two new energy-saving six-chamber Montex stenters which is characterised by a larger shrink cylinder allowing for longer processing paths to achieve enhanced shrinkage values The first stenter was manufactured at the Montex plant in Austria and was delivered installed and commissioned in a record time of less than four months “We were able to salvage our existing air cleaning system and after the first of the new stenters was up and running we were able to resume operations and build up back to where we were month by month,” said Mr Katzenstein All of the Monforts lines have working widths of 3.4 metres and benefit from the latest Qualitex 800 control system This has all of the familiar features of touchscreen smart phones and tablets making navigation easy and cutting down the time required for becoming familiar with the system Operation is via touchscreen and wheel-effect selection and the dashboard can be individually configured to meet the exact needs of an operator’s tasks The second Montex stenter that has been installed at the Zofingen plant is equipped with the latest Monforts texCoat system as an extension of Bethge services to its customers The latest Monforts coating heads are tailored to the company’s drying technology for maximum benefits Monforts offers multi-functional coating heads for its texCoat units with modules that can be integrated into new lines or retrofitted into existing ones Bethge also manufactures certain technical textiles as well as Damask fabrics and voiles destined for Africa’s apparel markets The company is now back to full production finishing some three million metres of fabric annually www.monforts.de Monforts coating competence at Techtextil 2019 New Monforts publications chart success in Europe Together with the R&D center in Zofingen, it will offer chemical process R&D and analytical development services for Siegfried's global drug substances network With workspaces for over 100 specialists and 40 new jobs created the R&D center strengthens Siegfried’s development capabilities in phase II and III supporting the company's Evolve+ strategy commented: “The new R&D Center in Evionnaz significantly enhances our Drug Substances network and demonstrates our unwavering commitment to providing cutting-edge research and development capabilities for our customers It will be a key element in driving development excellence as part of our Evolve+ strategy and represents another pivotal step in strengthening our position among the top providers in the CDMO sector." ProteiNext is an annual symposium that offers a platform for sharing insights on protein analysis create more value as an integrated supplier' the Swiss pharma outsourcing partner completed upgrading the Zofingen Switzerland facility for high containment drug products and acquired Alliance Medical Products in Irvine how these pieces fit into Siegfried's puzzle of offerings to meet and even exceed their customers' expectations CHEManager Europe: How would you judge the response your new slogan created in the markets you are serving?Marianne Späne: We are pleased with the slogan ‘expect more' as it represents Siegfried as a broad and full-fledged service partner Combined with our redesigned website and exhibition booth the slogan has been very well received by our customers and everyone understands Siegfried's position When a company makes a statement as strong as ‘expect more' to reflect its primary corporate message then expectations will be nothing short of the competition As we combined the slogan with concrete promises for expansion in 2012 we had to underline the commitment with actions because they walked that "extra mile" to meet and exceed customer expectations wherever possible What actions are you referring to?Marianne Späne: We strengthened our position as an integrated supplier through investment in supporting technologies for our business Switzerland facility for high containment drug products and mid-year we obtained approval for development and production of highly potent drug compounds from "Swissmedic" the Swiss agency for authorization and supervision of therapeutic products Thanks to this piece of the high-potency puzzle we can offer our customers a fully integrated continuous supply chain for high-containment products starting with API development through to commercial manufacturing of drug products.In addition we now offer micronization technology at both our global headquarters in Zofingen and at our U.S which further supports our promise to customers packaging and tableting capabilities to enhance oral applications production in Malta Didn't your stakeholders and customers expect more a bigger step forward?Marianne Späne: Naturally and I am pleased to say that they will receive more At the end of June we acquired Alliance Medical Products This acquisition clearly demonstrates our commitment as an integrated service provider In addition to our existing oral formulation and manufacturing capabilities in Malta we now offer sterile/aseptic development and manufacturing competencies in the USA Combined with our current chemical facilities in Pennsville and in Zofingen this additional site allows us to provide fully integrated services both in the US and in Europe Do AMP and Siegfried fit together?Marianne Späne: AMP works with unique and interesting customers that ideally complement Siegfried's current customer portfolio this provides us with a great potential for new business opportunities Our customers have expressed interest in forward integration and we are convinced that AMP's customers will appreciate backward integration into API for some of their products Siegfried and AMP as one company provide a US-focused customer the possibility to expand into Europe and other regions The 2012 CPhI convention coming up in October will be a great format for us to share with customers the unique opportunity they now have with our integrated sterile filling facility we are planning a combined customer road show with AMP experts within the next months It is great to see that AMP and Siegfried have a common desire for doing business together and both sides collectively enjoy the forthcoming opportunities makes AMP such a good fit?Marianne Späne: AMP is a unique fit for Siegfried because they are true specialists in producing sterile drug products and they offer a full range of aseptic-fill services for pharmaceutical biotechnological and medical device companies they provide small-run manual filling for special cartridges We plan to expand and augment their existing development and contract manufacturing focus We intend to do this by developing a portfolio to include our own IP combined with co-development and other creative business models customized to our customers' requirements AMP reports sales of about US-$ 20 million Do you expect significant short-term growth potential?Marianne Späne: Absolutely With some interesting phase-3 projects in the pipeline there is real growth potential At the same time we recognize that there is no guarantee that a phase-3 development will become commercial there are many promising opportunities at the evaluation stage: we are assessing our customers' interest in the forward integrated opiate business and in sterile high-containment drug products Market analysis tells us that around 80% of cytotoxic products are applied in sterile form We therefore have sufficient opportunities on our plate Other Siegfried business segments are also developing positively How do you view their growth potential?Marianne Späne: We are growing our opiate portfolio via new products and improving and sustaining our existing overall portfolio with optimized processes We naturally have to stay competitive and constantly offer lifecycle improvements we see an increasing interest in our oral formulation and manufacturing capabilities lifecycle management or contract manufacturing we have expanded our Malta capacity in tableting packaging and warehousing to cater for this growth Is this possible with a purely Western-hemisphere dominated company?Marianne Späne: It is an incredible challenge and we actively consider all opportunities to lower our costs at all times we are not in a position to compete on costs alone we try to offset the competition by working with our Asian partner and our USP as an integrated supplier with an effective supply chain and great quality practices this is not always enough to obtain new business.Based on these circumstances we have chosen to invest in our own factory in Nantong China - about two hours outside Shanghai - which will mirror our Zofingen site We plan to offer non-GMP substances beginning in 2014 and GMP substances from 2015 onward We are very excited about this opportunity as we can offer a secondary cost structure strategy and we will gain access to new markets such as China How can Siegfried manage all of these projects simultaneously?Marianne Späne: The key is a good team that shares the same strategy and is enthusiastic to be part of the growth and success of the organization We recognize that it is not an easy path to follow we have demonstrated that our talented team is strong enough to overcome such hurdles The infamous Powerman Zofingen in Switzerland the ITU Long Distance Duathlon World Championships had a different look to it on Sunday – because Great Britain’s Emma Pooley With the four-time consecutive winner (2014-17 inclusive) absent who finished sixth over three consecutive years but was unable to race for the last two editions The men’s Elite race saw a third win for Gaël Le Bellec (FRA) to add to his title from 2014 and 2015 He finished just over two and half minutes clear of another French athlete Congrats to Greenlighter Jane on winning Long Distance Duathlon World Champs 💪 10km run, 150km bike, 30km run🤮 pic.twitter.com/227TaNqdJ2 — GreenlightPT (@GreenlightPT) September 5, 2018 Follow the madness of the 'Race that eats its young' on RUN247 With an Olympic Silver and World Championship Gold medal on her extensive C.V Great Britain’s Emma Pooley has already cemented her status in the history books Returning to her multisport roots in 2014, Emma has since won three back-to-back titles at the infamous Powerman Zofingen in Switzerland which hosts the ITU World Long Distance Duathlon Championship After a brief return to cycling in 2016 to compete at Rio 2016 Pooley is now racing a range of events in triathlon duathlon and running – usually with as many hills as possible Emma will put that perfect record in an Elite GB Trisuit on the line this weekend at the ETU Middle Distance Duathlon European Championships The 10km / 60km / 10km (non-drafting) format is considerably shorter than the Zofingen monster (10km / 150km / 30km), but she will be up against Nina Brenn (SUI), who took the Silver medal in Zofingen last year. Brenn was the 2016 winner over the distance in Copenhagen Global (07 September 2023) — South African female endurance runners are having their moment in the spotlight and scooping podium victories across the world Christelle Hattingh put the power in the Powerman Zofingen for South Africa making a proud podium placement at the global duathlon event in Switzerland Christelle came in third for the long-distance duathlon for her age category and shared that she was also the speediest South African in—an apt charm for her third experience tackling the Powerman especially as race day was one of the hottest for the World Triathlon event “The route and competition is always tough,” Christelle tells Good Things Guy “the feeling of accomplishment once I have crossed that line is just priceless,” she adds the support from the Zofingen community also makes the many kilometres running and cycling (over 8 hours) worth it “I am so grateful for my Homestay Family Mariaan and Patric Ebeling who invited me into their home for the week leading up to Powerman I wish all my friends could also experience it in the way I did,” Christelle adds Her achievement follows that of another female South African trailblazer—Toni McCann who recently became the first local to ever win the Ultra-Trail du Mont-Blanc OCC in France last week—a first for South Africa Ashleigh Nefdt is a writer for Good Things Guy Ashleigh's favourite stories have always seen the hidden hero (without the cape) come to the rescue her labour of love is finding those everyday heroes and spotlighting their spark - especially those empowering women sustainability shakers and creatives with hearts of gold she's dedicated to her canvas or appreciating Mother Nature Comment * document.getElementById("comment").setAttribute( "id" "a856072bcdec8f5a5db724e933e73441" );document.getElementById("d2d9e305b5").setAttribute( "id" and website in this browser for the next time I comment Would you like to receive truly phenomenal inspirational and good thing stories right to your inbox Then subscribe to our weekly GoodThingsGuy newsletter today I accept GTG’s Privacy Policy GoodThingsGuy is the home of everything good and those are the things that really matter We believe that there is good news all around us and over 1 million readers a month agree with us GoodThingsGuy was officially launched on the 1 August 2015 in order to only promote good news inspirational stories and promote only positive multi-platform media company that distills unique content across multiple media platforms We consider individual and corporate contributions through the website or mail us directly here. Be sure you have your GPS enabled and try again Sprinter Alex Wilson has been banned for a further ten years by the Court of Arbitration for Sport for doping with EPO possession of prohibited substances and undue influence The four-year ban that Wilson received for a positive doping test would have expired next Monday Swiss Sport Integrity tested the now 34-year-old Swiss 100m record holder unannounced after a training camp in Las Vegas Swiss Sport Integrity then continued the investigation and commissioned a follow-up analysis of a blood sample taken in July 2021 This led to a positive result for erythropoietin (EPO) Wilson denied taking EPO in a statement shortly after the blood sample was analyzed Swiss Sport Integrity revealed that Wilson was in possession of banned substances Wilson is said to have deliberately provided false whereabouts information the facts are supported by the confession of naturopath Eric Lira before a court in the USA He is alleged to have supplied Wilson with growth hormones and EPO in 2021 the main hearing took place before the Swiss sports court which Wilson attended without excuse and without making a statement the ban for a second offense was increased from eight to ten years The new ban will come into effect on April 28 Wilson must also pay a fine and costs of CHF 17,400 Swiss Athletics welcomed the sanction against Alex Wilson: "In our view the severe penalty is absolutely justified in view of the repeated Managing Director of the athletics association He was "deeply disappointed" by the Basel athlete's behavior: "It contradicts all the values of sport which many people in Swiss athletics stand up for every day."