New research and EURETINA highlights from the director of the "underdog" eye clinic At this year's European Society of Retina Specialists (EURETINA) meeting visited the Ophthalmology Times Europe booth including central subfield thickness (CST) measurements in age-related macular degeneration (AMD) and diabetic macular oedema (DME) picking the right intraocular lenses for patients with geographic atrophy (GA) and interesting symposia from the congress including in-office applications of artificial intelligence (AI) Editor's note: The below transcript has been lightly edited for clarity I'm a professor of ophthalmology with a teaching affiliation at the University of Bonn but my main practice is at the Eye Clinic Sulzbach Germany Nobody knows Sulzbach—that's the sort of the underdog statement that we have all the time Sulzbach is sort of at the Southwest border we are the largest surgical retina centre in Germany and we're sort of top three in medical retina practice in Germany as well.So So one that I spoke about was fluid quantification with the RetInSight Fluid Monitor in the VABYSMO [faricimab-svoa] patients in a real-life cohort when you look at CST measurements compared to fluid quantification in AMD CST underestimates the drying with VABYSMO by two-fold in DME; it's a four-fold underestimation of CST Patients with DME get an up to 60% drying with VABYSMO up-load So this is first-time quantification of these data but it appeared to be reproducible among many sort of incremental data acquisitions that we had.The other contribution that we made at this meeting was that we had looked at a kind of new intraocular lens which was a monofocal lens that has a hyperspheric design And that is very interesting for patients who have some form of macular atrophy geographic atrophy is a big buzzword at this moment and so a lot of these patients who have a macular atrophy have a lost fixation fixation is something that you can quantify with microperimetry when you first turn on microperimetry devices they do something what is called a fixation cloud the lesser the ability of a patient to fixate Our theory was that if you put in a regular lens then the IOL is basically [shining] the optical path onto the macular scar But by using a lens that has a wider viewing angle you can actually look at the somewhat healthier areas at the edges of the scar and thereby perhaps shrink that fixation cloud this is exactly what happened in a smaller cohort of patients Were basically independent of the sort of approval and transparency an unexplored niche in sort of visual rehabilitation of patients So this is really just exploratory at the moment but I think this is a very interesting technology that once you get sort of the hang of this lens and what it can do you start seeing so many patients who have macular disease we can put it in What else did I sort of get excited about at this meeting then you need to go to your clinic manager I came across a pitch presentation at the EURETINA Innovation Symposium and it will go into your medical record and pull those patients for you." Fantastic I'm not saying AI is replacing people Join ophthalmologists across Europe—sign up for exclusive updates and innovations in surgical techniques and clinical care Editorial Advisory Board members bring research findings to ARVO Ophthalmology Times and Modern Retina editorial advisory boards are present and presenting at the 2025 ARVO meeting PHOTON Results and Their Relation to DME Patients in Your Practice to discuss the PHOTON trial results and their relation to patients with diabetic macular oedema in clinical practice LuxIA receives CE-MDR certification LuxIA is designed to screen adult diabetic patients for more-than-mild diabetic retinopathy PULSAR Results and Their Relation to nAMD Patients in Your Practice to discuss the PULSAR study results and their relation to patients with neovascular age-related macular degeneration in clinical practice The future of microbial keratitis treatment is bright Ultraviolet light’s potential in ocular care extends beyond structural reinforcement to antimicrobial applications Daniela Ferrara appointed by Topcon Healthcare as CMO Topcon Healthcare has appointed Daniela Ferrara as chief medical officer to lead the company’s clinical and medical strategy 609-716-7777 Roberto Gualdoni started his professional career in 1983 as a Commercial Coordinator for the global seamless steel pipe business at Tenaris in Buenos Aires where he held various management positions over the years including Group Vice President of the Foam Products Business Unit from 1998 to 2001 Group Vice President of the Engineering Plastics Europe Business Unit from 2001 to 2005 Senior Vice President of Global Procurement Basic Products from 2006 to 2007 and Senior Vice President Global Procurement Raw Materials from 2007 to 2010 he became President of BASF's Styrenics business unit which merged with INEOS units to form the Styrolution Group a global leader in styrenics for the automotive Roberto Gualdoni holds a degree in industrial engineering from the University of Buenos Aires and he also graduated with an MBA from INSEAD in Fontainebleau Please select what you would like included for printing: Copy the text below and then paste that into your favorite email application Andrea Helma Strange passed away on Thursday to Max Klaus Seiler and Paulina (Berbner) Seiler especially returning to visit her family and friends in Germany She enjoyed shopping and going to antique stores Her laughter was contagious and she always brought a smile to the faces of those she loved. She was also an active member of her church. Andrea’s most favorite role was being a loving wife Andrea is preceded in death by her father Max. She is survived by her loving husband Mark Strange and Connor Strange. She is also survived by her grandchildren Addison Gross Lillian Gross and Emilia Strange. In addition she is survived by her brothers Frank (Monika) Seiler along with her sisters Marion (Karl) Stein from 5pm-7pm at Hendersonville Funeral Home. A Celebration of Life will be held on Wednesday at 2pm with visitation beginning at 1pm followed by a committal service at Hendersonville Memory Gardens the family requests that donations be made in Andrea’s name to the American Cancer Society Enter your phone number above to have directions sent via text Click to watch This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply Service map data © OpenStreetMap contributors Connecting decision makers to a dynamic network of information, people and ideas, Bloomberg quickly and accurately delivers business and financial information, news and insight around the world according to people familiar with the matter The private equity group is working with an adviser on a potential deal and has held initial talks with potential buyers asking not to be identified discussing private information First-round bids are due in early May and other private equity firms are expected to express interest Medical Design and Outsourcing December 3, 2018 By Nancy Crotti Implandata Ophthalmic Products announced that the first patient in its international ARGOS-SC01 clinical study has been successfully implanted with its novel pressure sensor This first-in-human clinical study is being conducted to validate the suprachoroidally placed Eyemate-SC a sensor implant for continual monitoring of intraocular pressure (IOP) While Implandata’s already CE-marked Eyemate-IO intraocular sensor implant is intended for use in glaucoma patients undergoing cataract surgery the Eyemate-SC device allows implantation in glaucoma patients not indicated for cataract surgery yet “The new Implandata sensor is pleasantly small and easy to surgically implant; therefore most patients undergoing glaucoma surgery are likely to be eligible candidates for such a pressure sensor,” said principal investigator Peter Szurman in a prepared statement Szurman performed the implantation of the Eyemate-SC device in conjunction with non-penetrating glaucoma surgery at the Eye Clinic Sulzbach of Knappschaft Hospital Saar “This breakthrough product enables glaucoma patients for the first time to monitor their own eye pressure at any point in time,” Szurman added “I expect that it will improve therapeutic compliance and also significantly reduce the risk of unnecessary visual field loss or even blindness due to glaucoma.” Intraocular pressure monitoring is a considerable challenge for glaucoma patients and their ophthalmologists Current IOP measurement methods require in-office procedures to be performed by trained medical staff these measurements are obtained just a few times a year although it is known that the eye pressure is highly dynamic influenced by many parameters and changes throughout the day continuous IOP measurements outside the ophthalmologist’s office enhancing treatment options and contributing to less vision loss in glaucoma patients Earlier studies demonstrated that the Eyemate system which provides direct feedback to the patient in a home setting It may also reduce the number of office visits and provide the ophthalmologist’s with more and better information about the patient’s specific situation the aggregation of IOP measurement data may shed new light on the emergence and progression patterns of the disease potentially unlocking new or more efficacious intervention approaches “The successful inclusion of the first Argos-SC01 study patient is a pivotal milestone for Implandata towards broadening the use of our Eyemate system eventually allowing also stand-alone implantation of our proprietary eye pressure sensing devices,” said Implandata CEO Max Ostermeier Implandata is expanding the study to other sites in Germany and Switzerland and expects it to be completed by early 2020 Subscribe to Medical Design & Outsourcing share and interact with the leading medical design engineering magazine today DeviceTalks is a conversation among medical technology leaders webinars and one-on-one exchanges of ideas & insights MassDevice is the leading medical device news business journal telling the stories of the devices that save lives Copyright © 2025 WTWH Media, LLC. 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Site Map | Privacy Policy | RSS Learn how to describe the purpose of the image (opens in a new tab) Leave empty if the image is purely decorative We're working on a visual shortcode editor until then please follow these instructions Email us to support@plugin.builders for any problems PDF Aim To investigate the safety and performance of a telemetric suprachoroidal intraocular pressure (IOP) sensor (EYEMATE-SC) and the accuracy of its IOP measurements in open angle glaucoma (OAG) patients undergoing simultaneous non-penetrating glaucoma surgery (NPGS) Twenty-four eyes of 24 patients with OAG regularly scheduled for NPGS (canaloplasty or deep sclerectomy) were simultaneously implanted with an EYEMATE-SC sensor Six-month follow-up on the sensor’s safety and performance as well as on the level of agreement between the EYEMATE-SC measurements and IOP measurements with Goldmann applanation tonometry (GAT) Results The eyes underwent canaloplasty (n=15) or deep sclerectomy (n=9) and achieved successful implantation of the sensor dislocation or serious device-related complications occurred A total of 367 comparisons were included in the IOP agreement analysis The overall mean difference between GAT and EYEMATE-SC measurements was 1.31 mm Hg (lower limit of agreement (LoA) 7.55 mm Hg; upper LoA –4.92 mm Hg) The maximum difference of 2.5 mm Hg ±3.96 (LoA 0.30–2.29) was reached on day 10 and continuously improved to an agreement of –0.15 mm Hg ±2.28 (LoA –1.24 to 0.89) after 6 months the percentage of eyes within an IOP difference of ±5 mm Hg improved from 78% (day 3) to 100% (6 months) the EYEMATE-SC sensor was safe and well tolerated Data may be obtained from a third party and are not publicly available https://doi.org/10.1136/bjophthalmol-2021-320023 If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service You will be able to get a quick price and instant permission to reuse the content in many different ways especially Goldmann applanation tonometry (GAT) require trained personnel and specialised equipment This limits IOP monitoring to isolated recordings during scheduled visits medical treatment decisions are mostly based on these few random IOP measurements continual IOP measurement is desirable for glaucoma monitoring The aim of this study was to investigate the safety and performance of the EYEMATE-SC suprachoroidal sensor and the accuracy of its IOP measurements in patients with open-angle glaucoma (OAG) undergoing simultaneous non-penetrating glaucoma surgery (NPGS) multicentre clinical investigation to assess the safety tolerability and performance of the EYEMATE-SC suprachoroidal pressure sensor system in patients with OAG undergoing NPGS The study was conducted at five investigational sites in two countries The primary objective was to evaluate the safety tolerability and performance of the EYEMATE-SC system during implantation and throughout a 6-month follow-up period The secondary objective of the study was to evaluate the level of agreement between measurements with GAT and the EYEMATE-SC system The study included 24 patients of legal age with OAG who were scheduled for NPGS The medical indication for NPGS had to be given irrespectively of study participation Potential study patients had given their consent to NPGS before joining the study Female patients had to have a negative pregnancy test performed prior to surgery Only one eye per patient was eligible for treatment although both eyes could be screened for inclusion Exclusion criteria comprised neovascular and angle-closure glaucoma prior glaucoma surgery and other ocular surgery procedures within 6 months (cataract surgery within 3 months) prior to EYEMATE-SC implantation or evidence of ocular diseases other than glaucoma patients with other active medical implants in the head/neck region or a serious generalised disease were excluded The EYEMATE-SC system consists of a cushion-shaped sensor device for permanent implantation into the suprachoroidal space and an external handheld reader device (Mesograph) (see figure 1) (A) Front view (vitreous site) depicting the sensor chip with integrated capacitive pressure sensor membranes and the wire-wound gold microcoil for power and digital data transmission Note the lenticularly rounded back surface to adapt to the curved scleral shape The EYEMATE-SC sensor bears the same micro-electromechanical system as the EYEMATE-IO implant,7–9 11 although the implant is miniaturised in its final dimensions (7.5×3.5 mm and an outwardly decreasing thickness of 1.3 mm at the centre and 0.9 mm in the periphery). The surface shape of the implant is lenticularly rounded to smoothly adapt to the curved scleral shape (figure 1A,B) The custom chip (application-specific integrated circuit ASIC) integrates pressure and temperature sensors identification and analog-to-digital encoders The ASIC is bonded to a wire-wound gold microcoil and hermetically encapsulated in validated medical-grade silicone rubber material Owing to the nature of metals contained in the device (gold and aluminium) it is entirely non-magnetic and has been tested for MRI safety The Mesograph consists of a power source, a coil for the electromagnetic field supplying the sensor with power, and an antenna for transmitting the signals (figure 1C) IOP is displayed on the LED display of the reader the system collects and averages 10 samples The reader can store up to 3000 IOP readings which can be transferred wired or wirelessly through a Global System for Mobile Communications module Each sensor is calibrated to be highly accurate before sterilisation and packaging and is checked for plausible readings immediately before implantation The implant is tested and certified for electromagnetic and radiation safety according to the requirements of the European medical device law The EYEMATE-SC implant can be placed either as a stand-alone procedure or in combination with glaucoma surgery we included eyes with scheduled NPGS (canaloplasty or deep sclerectomy) The rational is that the access to suprachoroidal space created during the NPGS can easily be used for placing the EYEMATE-SC sensor After conjunctival peritomy, a 5×5 mm superficial scleral flap is created. Below this, a deep scleral flap (4×4 mm) is prepared. Depending on the surgeon’s preference, the second flap is either prepared completely until the choroid is exposed (100% thickness technique, figure 2A–C) or a thin scleral lamella of 10–50 µm is preserved (90% thickness technique, figure 2D–F) The dissection is continued across the scleral spur to open Schlemm’s canal (SchC) After SchC is deroofed a trabecular-Descemet window is created The deep scleral flap is excised and juxtacanalicular TM is peeled SchC may additionally be dilated with viscoelastics (OVD; viscocanalostomy) or probed with a microcatheter and tensioned with a 10–0 prolene suture (canaloplasty) Two techniques for suprachoroidal implantation of the EYEMATE-SC sensor device. (A–C) Preparation with 100% thickness technique13: the deep flap is prepared until the choroid is completely exposed (A) viscoelastics are injected into the suprachoroidal space and the EYEMATE-SC sensor is carefully inserted using padded implantation forceps (B) The sensor is buried in the suprachoroidal space acting as a spacer for suprachoroidal drainage (D–F) Preparation with 90% thickness technique: the deep flap is prepared und a thin scleral lamella preserved; the choroid is not exposed (D) a 5 mm incision in the remaining thin scleral lamella is made (D) and the EYEMATE-SC sensor is inserted into the suprachoroidal space (E) the sensor is buried in the suprachoroidal space without additional suprachoroidal drainage (F) suprachoroidal space is accessed either through the window (100% thickness technique) or through a 5 mm incision in the remaining scleral lamella (90% thickness technique) The choroid is separated from the sclera by means of OVD and the EYEMATE-SC implant is carefully inserted into the suprachoroidal space using padded implantation forceps and avoiding contact with the sensor’s ASIC the superficial scleral flap and the conjunctiva are closed and sutured Follow-up examinations were performed on days 1 An ophthalmological examination including best-corrected visual acuity funduscopy and tonometry was performed at each visit External eye photography and optical coherence tomography (OCT) of the anterior segment were performed at baseline visit and days 10 Tonometry was performed using GAT and EYEMATE-SC at each visit EYEMATE measurements were performed by the patients GAT was performed with two measurements; in case of a difference of more than 2 mm Hg In order to avoid operator/investigator bias GAT measurements were taken directly prior to EYEMATE measurements to ensure the investigator is unaware of the EYEMATE result All patients received the reading unit for long-term self-tonometry and were encouraged to measure IOP at home regularly The safety population included all subjects in whom EYEMATE-SC implantation was attempted The per-protocol set comprised all subjects in whom the sensor was successfully implanted and for whom the full dataset was available until month 6 Bland-Altman plots were used to evaluate the mean difference and 95% limit of agreement (LoA) in IOP measurements between the averages of GAT and EYEMATE-SC at each study visit.13 The Pearson correlation coefficient r was used to measure the strength of the agreement between GAT and EYEMATE-SC on the scatter plot the mean difference in the measurements between the two methods on the Bland-Altman plot was the estimate of the fixed bias The probability distribution of the difference of the paired measurements grouped within 1 mm Hg was compared with the primary objective of the accepted 70% of the measurements to agree between ±5 mm Hg Statistical analysis was performed using the statistical software Stata V.14.2 (StataCorp) A p≤0.05 was considered statistically significant The 24 patients who met the inclusion criteria originated from 5 centres and 7 surgeons performed the surgeries 2 eyes underwent combined cataract surgery Primary OAG was the predominant diagnosis (n=20) pigment dispersion (n=1) and uveitic glaucoma (n=1) Mean preoperative IOP was 19.4±5.4 mm Hg (range: 12–37 mm Hg) with a mean number of antiglaucomatous medication of 2.8±0.8 (range: 0–4) The patients underwent the procedure with either canaloplasty (n=15) or deep sclerectomy (n=9) EYEMATE-SC implantation was successful in all cases and all implanted sensors remained in the eye during follow-up All patients completed the 3-month follow-up and 21 patients completed the 6-month follow-up 3 patients missed the follow-up due to COVID-19 The implantation of the EYEMATE-SC succeeded without complications in all eyes No intraoperative injury of the choroid or bleeding from the entry site were reported In all cases the sensor could be implanted with the right orientation (ASIC towards the choroid) During the first 6 months, no serious or sight-threatening complications occurred. Figure 3 shows the postoperative anterior segment photography of a patient at day 10 and 90 Postoperative anterior segment photography of a patient at day 10 (A) and at day 90 (B) The most frequent postoperative complication was hyphaema which occurred in nine eyes (seven after canaloplasty two after deep sclerectomy) and resolved spontaneously in all cases Two patients had superficial punctate keratitis for 3 weeks One patient showed early postoperative leakage one patient had choroidal detachment and hypotony for 3 weeks One patient complained about postoperative photopsia for 5 weeks two reported slight pain in the operative area The touch sensitivity was assessed as possibly device related All other AEs were assessed and determined to be caused by the surgical intervention itself No serious AEs related to the EYEMATE-SC sensor were reported The position, orientation and distance of the sensor from the scleral spur, which were measured by anterior segment OCT and 50 MHz ultrasound biomicroscopy, showed complete spatial stability. There were no reports of device migration, rotation or dislocation (figure 4) partially inserted into the suprachoroidal space at the end of surgery with approximately 1/6th remaining in the deep scleral lake slipped back early postoperatively into the suprachoroidal space and remained stable there Multimodal imaging 6 months after suprachoroidal implantation of the EYEMATE-SC sensor using AS-OCT (A B) and 50 MHz ultrasound biomicroscopy (UBM It shows the sensor remaining stable underneath the choroid (orange line) at the site of implantation AS-OCT visualises the microelectronics carrier substrate (■) and the gold coil (▲) but not the silicone encapsulation (* and green line) UBM depicts the lenticularly rounded silicone encapsulation smoothly adapting to the curved scleral shape anterior segment optical coherence tomography No permanent device malfunction occurred. Bland-Altman plots were used for analysing the agreement between the measurement with GAT and EYEMATE-SC throughout the follow-up visits (figure 5) A total of 405 comparisons were included in the analysis The overall mean measurement difference for all pressure sensors and all follow-up measurements was 1.31 mm Hg (lower LoA 7.55 mm Hg; upper LoA –4.92 mm Hg) Bland-Altman analysis of agreement between GAT and EYEMATE-SC (95% CI) available postoperative study from day 1 to day 180 are plotted The bold black line represents the average over all comparisons; red and green dashed-dotted lines represent the upper and lower level of agreement (LoAs An analysis over time shows that during the first month the EYEMATE-SC IOP values were significantly higher than the GAT measurements with a maximum difference of 2.5 mm Hg ±3.96 (LoA 0.30–2.29) at day 10 the overall bias between the two methods significantly declined reaching an satisfying agreement after 3 and 6 months the percentage of eyes where the difference in the IOP measurement between GAT and EYEMATE-SC was within ±5 mm Hg improved from 78% (day 3) to 100% (6 months) Scatter plot of all paired GAT/EYEMATE-SC comparisons It reveals that the deviation is evenly and closely distributed around the idealised zero error line (dotted line) The best fit linear regression line (red dash dot) shows a slight positive bias towards lower IOP values all eyes achieved agreement within the targeted ±5 mm Hg and a mean difference of –0.15 mm Hg ±2.28 SD (LoA –1.24 to 0.89) Bland-Altman analysis of agreement between Goldmann applanation tonometry (GAT) and the EYEMATE-SC (95% CI) Only data available from day 90 and day 180 are plotted to exclude the postoperative interval of increased astigmatism the lower limit of agreement (LOA) significantly improved to LOA –4.6/+4.9 mm Hg The bold black line represents the average over all comparisons; red and green dashed-dotted lines represent the upper and lower LOA (mean difference +/–1.96 SDs) Deviation between EYEMATE-SC and Goldmann tonometry presented with corneal astigmatism values at the different time points The 6-month interim evaluation shows that the EYEMATE-SC sensor is a safe and well-tolerated suprachoroidal implant that allows continuous IOP monitoring of glaucoma patients This suprachoroidal approach was developed to solve these limitations The EYEMATE-SC system consists of a miniaturised IOP sensor that is implanted into suprachoroidal space It can be used independent of the lens status and is also suitable for younger glaucoma patients for whom continuous IOP monitoring is particularly important Implantation can also be combined with trabeculectomy The long-term goal is a further miniaturised device for very small incision implantation in a stand-alone procedure preferably in one of the lower quadrants to leave space in the upper ones for glaucoma surgery If YAG goniopuncture is needed after NPGS to enhance the pressure-lowering effect a loss of sensor function is physically unlikely The experiences we have made with YAG capsulotomy in the Eyemate IO study as well as two cases where a YAG goniopuncture was performed after Eyemate-SC implantation show that after recalibration the sensor function was flawless In our study, transient deviations were observed in the agreement between GAT and the telemetric EYEMATE-SC IOP within the first few weeks after implantation; the deviations normalised after 3 months. This was concomitant but not directly correlated with a temporarily observed significant increase in postoperative astigmatism due to the scleral flap sutures of the NPGS (see table 1) our experience from clinical practice shows that it is very difficult to achieve reliable IOP values with GAT in hypotonic eyes And in the first 2 weeks after a canaloplasty or deep sclerectomy hypotony is common as the sutures are not immediately watertight assume that telemetric IOP measurements achieve a higher validity than GAT especially in eyes with altered corneal biomechanics and at abnormal IOP levels without comparing the values with real-time IOP measurement using intraocular probes this assumption remains merely speculative Limitations of this study include the relatively small and heterogeneous patient population The follow-up period is still relatively short but the 6-month interim analysis was intended to focus on safety and performance in the postoperative healing process potential explantability of the implant has only been proven in human autopsy eyes and in rabbit experiments Further observations are necessary to assess the long-term safety performance and reliability of the implant and the system the EYEMATE-SC is the first suprachoroidal sensor for telemetric IOP measurement It has been successfully and safely implanted in all 24 patients during simultaneous NPGS The 6-month evaluation showed no severe complications The suprachoroidal sensor allows continuous telemetric IOP self-measurement even under conditions where the validity of the GAT may be limited The study protocol was approved by the ethics committee of Saarland (ID:CIV-18-07-025065) and followed the tenets of the Declaration of Helsinki The authors thank the EYEMATE-SC study investigators and clinical research teams for their dedication and support Collaborators The EYEMATE-SC study group: Further Study Team: Eye Clinic Sulzbach: Arno Haus MD University Eye Clinic Bochum: Matthias Elling,MD MD University Medical Center Mainz: Katrin Lorenz MD Ludwig-Maximilians-University Munich: Matthias Nobl Contributors The authors are justifiably credited with authorship HLR and A-MS—data analysis and interpretation Funding This study received support from Implandata Ophthalmic Products which produced and provided the medical devices under investigation Competing interests PS has a pending international patent for the EYEMATE-SC system (PCT/EP2015/062976) Thea outside the submitted work; KM reports grants from Implandata (C) and non-related financial disclosures from Santen (C) Oertli (C) MM reports grants from Implandata (C) and non-related financial disclosures from Acufocus HLR reports consulting fees from Santen and Allergan and research support from Carl Zeiss Meditec Provenance and peer review Not commissioned; externally peer reviewed Barbara (Barbie) Liss and their fur baby Karlee and husband to his soulmate and best friend Seppi will be remembered for his love for life He loved to spend time with his family and friends Seppi was a known ‘parrot head’ attending many Jimmy Buffet concerts He was an avid sports fan of the Detroit Lions and Michigan Wolverines along with going to Detroit Tigers spring training in Florida every year of Gaylord for 9 years as an assistant manager He loved working with his co-workers and interacting with the customers He was preceded in death by his mother Margot (Rau) Natter; maternal Grandparents Richard and Lina Rau from Sulzbach Germany; Paternal Grandparents Katharia and Hermann Natter of Au The memory of his life will be fondly cherished by those he left behind; Hubert “Sepp” and Diana; sister Tanya (John) Thode; niece and goddaughter Sadie Sue; step sisters Nicole (Dean) Christner On Barbara’s side he leaves behind his in-laws Paul and Christina Liss Mandy Liss; cousin and godson William Bronson A mass of Christian burial will be held Tuesday at Noon with a visitation beginning at 11:00 a.m Visitation at the Nelson Funeral Home will be Monday from 4:00 until 7:00 with a rosary being offered at 6:45 p.m Mary Cathedral Schools through the Nelson Funeral Home Designed to reduce the symptoms of tremors by detecting muscle signals and providing electrical stimuli in response the human-machine interface is in development at the Fraunhofer Institute for Biomedical Engineering (IBMT) in Sulzbach The implants are made from biocompatible platinum-iridium and silicone and are injected into the muscle through a catheter Just three centimetres long and a millimetre in diameter the tiny implant has an electrode at each end that functions as either a sensor or an actuator External electrodes sewn into a textile ribbon supply the module with energy sending pulsed alternating current through the muscle tissue. the sensors register the first signs of muscle tremors and pass the information on to the external components The controller evaluates the data and sends signals through the textile electrodes to stimulate the muscle This closes a ‘control circuit’ of sensor and actuator components The stimulus signal is not strong enough to trigger a muscle contraction directly the nervous system registers the stimulation in the muscle tissue and responds by stopping the commands that trigger the muscle tremor. The finer details of the relationship between tremors and signals from the nervous system are yet to be researched Initial trials have shown that providing the patient with stimuli for one or two hours is enough to reduce tremor symptoms for a longer period of time,” said Andreas Schneider-Ickert project manager for active implants and innovation manager. “We have managed to reduce muscle tremors significantly in trials with patients.” Since tremors often occur in both arms and both legs implants can be injected and external textile electrodes placed in all the affected muscle groups creating a distributed sensor network. The controllers keep track of all the implanted and external electrodes at the same time and control them in coordination with each other with the patient reportedly experiencing no delay The system is part of the EU-funded Extend project in which nine partners from five countries are developing a versatile platform of distributed neural interfaces The technology is aimed at helping people with neuromuscular disorders such as tremors or symptoms of paralysis. The platform uses external controllers to link implanted electrodes into an intelligent network The components communicate with each other wirelessly detecting muscle signals and sending targeted stimuli into the muscles. Technology being developed in the Extend project is minimally invasive so could be easier to implement than conventional implanted systems. The technology platform could also help people with spinal cord injuries Sensors would register stimuli sent to nerves from the brain which would then activate the right prosthesis to support the muscles to execute the movement the concepts and technologies used in Extend have been developed optimised and subjected to further implementation studies with a successful proof of concept of the miniaturised system in humans. Fraunhofer IBMT will use the knowledge gained from Extend to develop its expertise in the field of neuromuscular and neural interfaces Want the best engineering stories delivered straight to your inbox? The Professional Engineering newsletter gives you vital updates on the most cutting-edge engineering and exciting new job opportunities. To sign up, click here Content published by Professional Engineering does not necessarily represent the views of the Institution of Mechanical Engineers Please enable JavaScript to view the comments powered by Disqus. Read now Download our Professional Engineering app Subscribe to Professional Engineering newsletter Opt into your industry sector newsletter Please enable Javascript on your browser to view our news. Flexible spaces at our head office in Westminster, London Reading"“The main thing is love,..." More fromWork Contact Advertising Opportunities Newsletters Insights + Opinion Creatives + Projects Advice + Resources Culture + Lifestyle Nicer Tuesdays The View From... POV Forward Thinking Review of the Year Jenny Brewer Olivia Hingley Ellis Tree Elizabeth Goodspeed Liz Gorny Extra Search really”: Mikey Yates paints sweet memories of his family and friendsHaving grown up within an itinerant military family the Filipino American artist looks back to his past for inspiration It’s not uncommon for an artist to turn an eye onto their personal life for inspiration does just this by using his medium to make sense of his past was in the army and was stationed in Germany when he was born and between them there’s a total of around 40 years worth’ of military Mikey and his family have lived in various places like Germany “My mum and two older brothers are from the Philippines so we kept that culture with us everywhere we moved – most of my family still lives in Manila,” he tells It’s Nice That Mikey would often find himself drawn to the subject matter of Mortal Kombat and its iconic 3D characters He’d often put pencil to paper in his own time but it wasn’t until the age of 22 that Mikey started to take it seriously – he was “I took my first drawing class in college where you stand up and draw still lives with charcoal This class inspired him to swap his major and soon enough he was knee-deep in the arts Mikey’s paintings are immensely autobiographical people playing basketball and someone doing the washing up Mikey’s subject matter appears a little more intimate The artist has painted his friends and family for his first solo show at Taylor Grahne Projects The works involved are all newly commissioned and depict a compilation of storytelling and portraiture where each piece has been inspired by a specific time or place my paintings are of memories from a few years ago,” he explains my paintings are of what I’m experiencing this week and usually it has to do with the people and things closest to me.” Courtesy Mikey Yates and Taymour Grahne Projects These moments arise from all sorts of memories but more often than not it’s from the various American states he’s lived in as well as his experiences of growing up within an itinerant military family A mishmash of cultures and locations belie the work a vibrant bricolage of everything he’s ever been influenced by and most pieces tend to start off a little differently than the other “I’m usually operating on the outer edges of what I’m comfortable with,” he adds “so each piece feels experimental.” For this specific body of work – the first since graduating from school and also the first he’s created using almost solely acrylic paint – he started off with drawings from snapshots of his family he recomposed the compositions and continued to build on the image “I really wanted to try and follow my intuition and forget some of the grad school overthinking that was going on.” Coffee and Cassava Cake with Mom in Texas (2021) is one of Mikey’s favourite pieces from the series It depicts a portrait of his mum amongst her own space with her belongings Mikey has painted the military building Ft “She just found out she needed to unexpectedly move again because of the military,” he says I saw her sitting room get unpacked in the new house in the exact same way it was in the old house: the colourful chair the grandfather clock and my brother's childhood painting.” For this painting Mikey was inspired by the “semblance of normalcy” and how his home was always his safe space growing up a place to shelter from the constantly changing outside world Mikey depicts himself and his father playing chess Inspired by the many nights he and his brothers would play the board game with their father the piece therefore sings with a sense of familiarity and closeness – it’s “set up as a contest and a confessional; when we play chess we talk one-on-one and exchange stories and ideas in private.” This painting evokes a sense of love and memory – there’s always a story behind it giving them their flowers while they are still here.” Love Letters is on view at Taymour Grahne from 23 October - 20 November 2021 Mikey Yates: Coffee and Cassava Cake with Mom in Texas Mikey Yates: Christmas in California (Auntie Nen’s Apartment) Mikey Yates: Olyvia Making Student Examples for Class Mikey Yates: Priscilla buying Mom flowers (Honolulu) 2021 Acrylic and oil pastel on cradled wood panel Further Infowww.mikeyyates.net www.instagram.com/mikey_yates www.taymourgrahne.com Ayla Angelos Ayla is a London-based freelance writer After joining It’s Nice That in 2017 as editorial assistant she was interim online editor in 2022/2023 and continues to work with us on a freelance basis and she is also the managing editor of design magazine Anima Fancy a bit of It's Nice That in your inbox Sign up to our newsletters and we'll keep you in the loop with everything good going on in the creative world Instagram TikTok LinkedIn Facebook Twitter Pinterest About Careers at It’s Nice That Privacy Policy Insights Residence Creative Lives in Progress If You Could Jobs © It’s Nice That 2024 · Nice Face Logo © It’s Nice That Ayla is a London-based freelance writer this custom title design balances broken structures with ornate details to embody the protagonist’s sense of disconnection The photographer Ana Flores joined us at April’s Nicer Tuesdays to talk the crowd through her career to date from going with her gut and leaving a background in law to study fashion photography rediscovering her Peruvian roots along the way Ana took us through the process behind some of the projects that have led her to document the indigenous women of her birthplace with a focus on adornment The photographer explores masculinity within domestic spaces in Taiwan and the UK blurring the lines between performance and documentary Following the release of his debut book, New York Nico’s Guide to NYC the director and documentary filmmaker Nicolas Heller sat down with our US editor at large Elizabeth Goodspeed to discuss the origins of his widely loved Instagram page his career in filmmaking thus far and why he’s intent on capturing the city’s most charismatic characters Drawing on her personal experience with depression the artist and photographer has collated several years of still life imagery that mirrors internal emotional states writer and “sometimes artist” took to the New York Nicer Tuesdays stage to share the story behind the development of Bread on Earth: a project archive and umbrella for the research and experiments that she undertakes to better understand bread By offering a different view on the magic of the mundane carb Lexie shows us how the simple foodstuff can be an agent of personal and cultural identity – a gateway to bigger conversations about what it means to be human Elena’s compassionate project was designed for her own son as a tool for connection lens-based artist Daniela Spector outlined how archiving came to be the central purpose of her photographic practice to the creation of her project I Forbid You to Forget Me Daniela detailed her journey through grief and the ways she’s found to make work that carries some of the weight of it Contemporary Haggadot are upending tradition and asking what freedom – and Jewishness – look like now A shocking photograph of the artist’s grandfather in a newspaper triggered a deeply personal journey to unearth hidden family histories The biannual magazine is exploring the “universal yet deeply intimate” subject of the home through a range of inventive personal submissions The London-based painter’s earthy palettes swirl through surreal scenes that merge family archives and fiction to create new and imagined realities www.mikeyyates.net www.instagram.com/mikey_yates www.taymourgrahne.com Love Letters is on view at Taymour Grahne from 23 October - 20 November 2021 While focusing on moments from his everyday life this painter never paints from photographs he lets memory and imagination lead the way The Barcelona-based visual artist is transforming reality into blotchy collaged forms that merge medieval and folkloric inspirations The comedian and artist describes the collection of paintings and accompanying essays as some of his “greatest artistic achievements” Read on to find out all about the drama surrounding that infamous Harry Styles portrait The Helsinki-based artist’s surreal and sensual works are drawn from constant detailed observation and scenes she discovers when her head is in the clouds Having grown up within an itinerant military family About Contact Advertising Opportunities Newsletters Insights + Opinion Creatives + Projects Advice + Resources Culture + Lifestyle Nicer Tuesdays The View From... POV Forward Thinking Review of the Year Jenny Brewer Olivia Hingley Ellis Tree Elizabeth Goodspeed Liz Gorny Instagram TikTok LinkedIn Facebook Twitter Pinterest Careers at It’s Nice That Privacy Policy Insights Residence Creative Lives in Progress If You Could Jobs The team at the Fraunhofer Institute for Biomedical Engineering (IBMT) in Sulzbach are working as part of an EU research project to improve control of prosthetic hands Conventional myoelectric prostheses usually use electrodes placed on the skin which pick up electrical signals from muscle contractions and send them to an electronics module the researchers said they have shown that controlling prosthetic hands can be improved using ultrasonic sensors with “far greater” accuracy and sensitivity in commands The new technique uses ultrasonic sensors that continuously send sound pulses into the muscle tissue in the forearm and the time they take to propagate provides information about the depth of the muscle strand that is reflecting the wave This allows contractions in the muscle tissue to be studied in great detail allowing the identification of ‘activation patterns’ for specific movements The aim of the project is for AI-controlled software to handle that identification via an electronic box worn on the user’s body The electronics could then send decoded signals as commands to the actuators in the prosthetic hand triggering movement of the prosthetic fingers “The ultrasonic-based control acts with greater sensitivity and accuracy than would be possible with electrodes The sensors are able to detect varying degrees of freedom such as flexing extending or rotating,” said Dr Marc Fournelle head of the Sensors & Actuators group at Fraunhofer IBMT Piezoelectric sound transducers used in the project send impulses at frequencies from 1-4MHz each one providing data about the position of muscle strands The sensors are currently integrated into a bracelet which might be fitted into the shaft of the prosthetic hand at a later stage Users have to complete a short training session to link the muscle signals with the correct fingers and desired movements Imperial College London developed the AI process for recognising movement patterns and carried out initial testing on subjects. the researchers want to improve the temporal resolution of the sensors and make the electronics smaller so that the prosthesis can be controlled even more accurately and comfortably They also want to make the system bidirectional with the brain receiving sensory stimuli from the prosthesis The feedback could be delivered via electrodes implanted in “When someone who hasn’t lost their hand picks up a glass of water and holds it to their mouth they get constant feedback from their fingers on how tight to hold the glass so that on the one hand it doesn’t slip and fall and on the other so it doesn’t shatter from being squeezed too tightly Such functionality is also being investigated within Soma and could one day be integrated into prosthetic hands,” said Andreas Schneider-Ickert project manager in the Active Implants unit and innovation manager at Fraunhofer IBMT Please enable Javascript on your browser to view our news Flexible spaces at our head office in Westminster Source: Abercrombie & Fitch Corporate Source: Insider Old Hollister stores have also gone through one of the more popular transformations during the Retail Apocalypse — thriving retailer to haunted house the Mall of Abilene in Texas transformed its Hollister location into a fully operational mini golf course which opened in 2017 and has since permanently closed maintained a sense of the Hollister spirit by keeping the lighting quite dim — the course was completely glow-in-the-dark A recent viral TikTok shows a former Hollister location at the Valley View Mall in LaCrosse "I can't explain why but my hometown mall turning Hollister into an escape room and just leaving the aesthetic is sending me into space," user @freshsketti wrote. which has now been viewed nearly 500,000 times writing "love what they're doing with the place." As documented by TikTok user @venusflytrap42 one Hollister store has even been converted into a sock store aptly titled "Socks To Be You." capturing images of children dressed in fairy costumes Several abandoned Hollister locations seemingly have been transformed into bookstores with many of the new stores keeping the old Hollisters. The above store became an outlet bookstore becoming a used bookstore with an eclectic mix children's books and collectibles. "Visiting your hometown mall on a Friday night That book store was once a Hollister," TikTok user @sarahgaliant0 wrote in reference to the used bookstore "2009 me would never ever thought I'd see a Hollister turned into a bookstore," one user commented Just when you thought defunct Hollister stores couldn't possibly evolve into any other form of experiential retail one location in Pennsylvania's Monroeville Mall became an axe-throwing venue. mall-goers could walk through the doors of an old Hollister and hurl axes at a bullseye target served the United States for more than 25 years as a member of both the United States Army and United States Air Force ELKINS — Throughout his more than 25-year military career an Elkins man helped to bring home a number of prisoners of war served as a member of the United States Army from August 1958 through the summer of 1964 when he retired as a Specialist E-5 He returned to the military as a member of the United States Air Force in January 1968 as part of “Operation Homecoming,” Lothes was involved in bringing two West Virginian POWs home from Hanoi Vietnam — Gail Kerns of Valley Bend and Joseph Rose of Morgantown “I just happened to be on the flight that brought him out of Hanoi.” POW rescue flight he was involved in two other POW rescue missions — one in February 1973 and another on March 29 Lothes also assisted with several significant aeromedical evacuation missions including helping victims of the hijacked cruise ship “Achille Lauro” on Oct 1986; helping victims of an international Pan Am 747 that was hijacked in Karachi “Victims of the hijacked cruise ship ‘Achille Lauro.’ It was a cruise ship off the coast of Italy A significant part of the mission for us was there was an elderly lady and her husband was in a wheelchair The terrorists shot him and threw him overboard,” Lothes said “We went and evacuated the victims from that There was also a Berlin disco bombing at a night club It was a terrorist attack on an establishment frequently visited by American soldiers and there was a bomb explosion “There was a Pan Am 747 hijacked in Karachi That was an American Pan Am 747 aircraft that was hijacked on the ground in Karachi and when an airplane is on the ground they have what they call an APU that runs the electricity on the plane,” he continued they forgot to keep gas in the APU so the lights went out in the airplane so the terrorists ran through the airplane shooting and throwing grenades so we sent an aerovac unit down to Karachi to bring those survivors back.” Lothes was also involved with roughly 30 humanitarian missions including being a crew member on missions that evacuated more than 600 freedom fighters “We evacuated over 630 Afghan freedom fighters to the United States for medical care when the Afghans were fighting the Russians The physicians in Texas agreed to give medical care to the Afghan freedom fighters that were fighting the Russians in Afghanistan,” Lothes said “He worked with the state department and the state department negotiated with the military department of defense and they arranged for the aerovac system once a month and these freedom fighters would come over the mountain and congregate in Islamabad,” he continued pick them up and fly them back to Rhein Main They would stay at the Wiesbaden Air Force Hospital of the Frankfurt (Germany) General Hospital overnight or until we had the next mission coming to the states We would bring them to (Andrews Air Force Base) and the domestic aerovac system would take them to Texas Lothes also spoke of three soldiers he knew — Tech Sgt medical tech — all three of whom lost their lives during the April 4 “Operation Baby Lift was during the evacuation of Saigon (Vietnam) when Saigon fell to evacuate these children out of Saigon and that airplane actually crashed,” Lothes said “Three aerovac crew members were lost during that incident Those are the three names on the Vietnam Wall that I actually knew Those are the only three names that I personally know on the Vietnam Veterans Memorial Wall in Washington Lothes also served as Military Airlift Command (MAC) Command Surgeon’s representative for the Advanced Medium Short Takeoff and Landing (AMST) aircraft and the Stretch C-141 project and started the Medical Readiness Internship Program in February 1985 He co-authored the article “Aeromedical Evacuation During Wartime,” which was published in the May/June 1982 edition of U.S Awards and decorations received by Lothes include the Air Force Meritorious Service Medal with three oak leaf clusters; the Air Medal; the Joint Service Commendation Medal; the U.S Army Good Conduct Medal; the Armed Forces Expeditionary Medal with three devices; the Humanitarian Service Medal with three devices; and the Republic of Vietnam Campaign Medal Lothes said the thing that sticks with him about his time in the service is the willingness of military personnel to go the extra mile for their country “I’m impressed the most by the willingness of the military individuals to give their all for their country they are willing to give their all for their country,” he said wife and children to go do things for the country at their expense their willingness to do whatever it takes.” he did so with a group of his friends from Elkins and the surrounding areas “There were 21 or 23 of us from Elkins in August of 1958 that joined the army and we went to basic training on the ‘Buddy Plan,'” Lothes said “They recruited us and we went in as a group The assignments they gave me ended up being the things that I loved.” Lothes served as a Fourth Ward Elkins City Councilman from 1993 to 1997 He was chairman for the safety committee and a member of the finance committee he was elected to the Randolph County Board of Education and served as board president the Air Force Association and the National Association for Uniform Services A 1957 graduate of Don Bosco Agriculture High School in Huttonsville Lothes earned a bachelor of arts degree in business administration from Davis & Elkins College the United States Air Force Reserve Officer Training Course (ROTC) program He later earned a masters degree in business administration from the University of Guam Married to the former Wilga Betty Pirner of Sulzbach-Rosenberg Copyright © 2025 Elkins Inter-Mountain Company | https://www.theintermountain.com | 520 Railroad Ave. gagged and severely beat her for two hours with the goal of ‘driving out the devil’ German police have arrested five members of a South Korean family suspected of beating to death a 41-year-old woman in a religious exorcism ritual in a hotel room The relatives allegedly believed that the woman was “possessed by demons” and tied her to a bed gagged and severely beat her for two hours with the goal of “driving out the devil” “I have never seen anything like it,” said Nadja Niesen The body was found Saturday in a hotel room where the five suspects – a 44-year-old woman her 21-year-old son and 19-year-old daughter one of whom was the victim’s son – were arrested on suspicion of murder The cause of death was “suffocation due to massive chest compression and trauma to the neck” Officials said the woman’s killers used “severe violence” against her beating her chest and stomach while gagging her with a towel and then a cloth-covered coat hanger The national news agency DPA reported that the family were of unknown religious affiliation and had arrived in the city around six weeks earlier The investigation led police to discover a second suspected victim alive in the garage of a house the group had rented in the town of Sulzbach Suited for extrusion and injection molding FortronÂ® FX4382T1 PPS complies with FDA and EU food-contact regulations This unreinforced grade is formulated to deliver long-term durability over life of components found in food handling applications including conveyor systems for food processing Exhibiting hydrolysis resistanceÂ as well as moisture absorption of < 0 .05% product supports continuous use up to 329Â°F and offers chemical resistance at elevated temperatures View All White Papers & Case Studies View All Resources Select From Over 500,000 Industrial Suppliers compatible with all major CAD software systems Plasteurope.com is a business information platform for the European plastics industry It is part of KI Kunststoff Information and PIE Plastics Information Europe one of the leading content providers for the European plastics industry We offer daily updated business news and reports polymer prices and other services for the international plastics industry News | Polymer Prices | Suppliers Guide | Jobs | Register | Advertising A few months after the start of construction of the "Food Garden" the topping-out ceremony for this unique project was celebrated The opening of the new "Food Garden" with a total of eight food outlets is planned for spring 2025 The Main-Taunus-Zentrum - one of the largest and highest-turnover shopping centers in Germany - is being supplemented by a new highlight with the "Food Garden": a new lively and urban center with a high-quality varied gastronomy and food offer is being built in the middle of the open-air shopping center in Sulzbach near Frankfurt am Main Five free-standing restaurant buildings with partly covered attractively landscaped outdoor areas and sophisticated architecture are being created The new "Food Garden" will be built on an area of around 9,000 m² with around 4,000 m² of rental space in the heart of the shopping center in place of a former department store building The aim of the project is to supplement the high-quality tenant mix with additional highlights and an extensive gastronomic offer to further increase the quality of stay and length of stay in the Main-Taunus-Zentrum and to strengthen its character as an open A total of eight tenants will enhance the quality of the MTZ's gastronomic offering the existing unique selling points of the Main-Taunus-Zentrum with its greater gastronomic expertise will significantly strengthen the regional appeal of the MTZ Wood as the construction method for the project - A forest in the middle of the center Wood is used as the main building material in the construction of the new "Food Garden" - currently one of the most sustainable solutions in this area Kai Laumann is one of the most successful and experienced companies in the region when it comes to ecological and sustainable construction The basic structures of the five "Food Garden" buildings consist of an innovative and solid timber modular construction system This sustainable construction method offers ecological advantages over other building materials and leaves a small carbon footprint One 1m³ of spruce wood stores 1t of CO² 1,300 m³ of spruce wood is used in the "Food Garden" This amount is roughly equivalent to the amount of CO² that an average car would consume if it were to drive around the world 162 times Timber construction has other positive characteristics - it can be used to create highly efficient buildings The construction method can be used in such a way that the solid wood can make the most of its natural climate-regulating abilities: Temperature and humidity remain at a comfortable level "We are actively contributing to climate protection with this construction method The "Food Garden" is an exciting and challenging project that will be a real asset to the Main-Taunus-Zentrum," says Kai Laumann "I am delighted that the construction work for the "Food Garden" is on schedule and that we can celebrate the topping-out ceremony today The project is an impressive example of what the subsequent use of the former site which was home to a department store until 2021 The project is also unique in terms of sustainability: "The Food Garden is being built entirely in solid wood," says Center Manager Daniel Quaas Deutsche EuroShop and a closed-end real estate fund are investing around 28 million euros in the new project as owners which is also responsible for the operation and leasing of the center is responsible for the planning and implementation has over 170 stores on a sales area of over 90,000 m² Hollister and Zara as well as a multiplex cinema Attached you will find the names and descriptions of the new tenants in the future "Food Garden"