From dreamy castles to sprawling palaces and enchanted villages and cosmopolitan hubs
here are our ideas for the best day trips to take from Tübingen
past designs and concept cars in their dedicated exhibitions
You can reach Ludwigsburg within an hour from Tübingen
Esslingen is situated a mere 45-minute drive north from Tübingen and lures with an old town that oozes medieval charm
The Neckar River and several canals cut through the old town of half-timbered houses and create picture-perfect vistas for your holiday snaps
locals decorate their houses with fresh flowers
even adding to the idyllic charm of the town
you can explore Esslingen on foot or rent a paddle board to sail down the waterways
Viacheslav Lopatin / Shutterstock If you’re into fairytale castles (who isn’t?)
this one should take the number one spot of your list of priorities
Perched on a hilltop 30 minutes south of Tübingen
the beautiful castle emerges from the canopy and towers above a picturesque valley below
The interior is best explores as part of a guided tour which takes you around the lavishly decorated royal chambers
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© Kraft_Stoff / Shutterstock More magical bliss is brought about by Lichtenstein Castle
you might feel as if you’re about to enter a Disney film
You’re not alone – the serene setting has lured German filmmakers to the site before
Some of the highlights are the 15th and 16th-century glass art in the castle chapel
the weaponry and the royal chambers which are decorated with colourful murals
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Less than 40 minutes from USAG Stuttgart is the small city of Tübingen
Filled with beautiful architecture and quaint strollable streets
it has its own castle filled with history and museums plus plenty of places to eat
Tübingen is big enough that there are tons of things for everyone to do
but it is small enough to not feel overwhelming or tiring
E-mail :ji-knkak@mail.doshisha.ac.jp
fairy-tale city21 March 2022ShareSaveSrishti ChaudharyFeatures correspondentShareSaveWestend61/Getty Images(Credit: Westend61/Getty Images)Located in a German region famed for its frugality
Tübingen is known for its fiercely green reputation
where veganism and environmental friendliness are the default setting
we published many inspiring and amazing stories that made us fall in love with the world – and this is one our favourites.)
nestled between the alps of the Swabian region and the densely wooded Schönbuch nature park
a university city that would put most Disney locations to shame
The city is built around the almost perfectly preserved old town
(While historical centres of most German cities were destroyed during World War Two
just one bomb fell on Tübingen.) The river Neckar flows through the city centre
forming a little island – the Neckarinsel – which is covered with blossoms in the spring and shines golden in autumn
a German region famed for its frugality – and which is also one of the nation's sunniest spots
making it considerably more cheery than other parts of the country with more gloomy
I find it incredibly international," said Nele Neideck
I first came to Tübingen eight years ago to visit a friend
with its idyllic landscape and youthful vibe; out of the 90,000 residents
more than 27,000 are students at the University of Tübingen
feasted on Swabian specialties and travelled to parties in buses full of students
I never imagined that years later I'd be returning to make it home
But that's what Tübingen does: it pulls you in
the ease of living in a place as small and vibrant as this makes you never want to leave
But that's not all that characterises Tübingen: it's also innovative
green and allows the existence of alternative lifestyles
To put the city's singularity into context, Tübingen was one of the centres of the German student protests of 1968
which took place all over West Germany rejecting traditionalism and authority
which influenced the city's leftist and environmental sensibility
• Germany's futuristic city set in a forest
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• How can we be sustainable post Covid?
there are self-governed housing initiatives
where cooking and grocery shopping is organised collectively and is mostly vegan," explained Jenny Bröder
who has been living in Tübingen for 12 years and works at the university
"The people running and living in these housings are often politically active
cultivate an awareness for social and ecological topics
and contribute to the cultural scene by organising concerts
The food offered at these events is usually vegan too."
a lot of people I have met since moving here are vegetarian or vegan
and it's as common to ask if someone eats meat as it is to ask if they have allergies
Tübingen is even an official participant in Veganuary
the annual challenge that encourages people to go vegan for the month of January
"Our vegetarian offering of the day gets sold out much quicker than the meat offering," said Alok Damodaran, who runs a South Indian food truck in the city
This is significant in a country that is known for its sausage
Green politicians have been a part of the District Council since way back in 1979
And as a third of its population are students
the city is home to an educated community that is aware of environmental issues
It is this young and energetic spirit that allows for sustainability to be functional
Amelie Dietenberger and Kajetan Krott started baking vegan banana bread during the pandemic
first making individual deliveries and then turning it to a business supplying to several cafes
"Tübingen has a certain feel of being green and happy
which fits our project," said Dietenberger
"People are so supportive because it's a local initiative
and they especially appreciate it that we deliver it in an electric car."
virtually all the food is vegetarian or vegan
There are delicious böreks filled with spinach
"We are sold out every evening," Yalcin said
"A vegetarian Turkish bakery works here because of all the students
Tübingen is also constantly being redesigned and updated to be ever-more environmentally friendly. Wide and well-integrated bike lanes along with high parking fees makes the city very car unfriendly. An order passed in February 2022 declared that cars will no longer be allowed to drive on the city's central street
which will be reserved for buses and bikes
Students can travel on buses for free on weekends and after 19:00 in the evenings
while bus travel is free for everyone on Saturdays
(The local government even plans to make buses free all the time.)
Tübingen spends three times as much per capita on bicycle infrastructure than Copenhagen
And a new tax imposed at the beginning of 2022 – with Tübingen being the first city in Germany to implement it – has upgraded the green status of the city even further
The Verpackungssteuer(packaging tax) imposes an extra payment of fifty cents on any disposable packaging
from coffee cups to ice cream bowls to meal plates
Even pizza boxes and the foil around a takeaway falafel are taxed
Regardless of whether they're made from sustainable or recycled material
anything that is one-time use will be costlier
based on the principle that non-production is better than future recycling or disposal
The tax is already off to an encouraging start: the first few weeks resulted in up to 15% less waste in the city's rubbish bins
as more people get in the habit of bringing their own cutlery and restaurants start providing reusable dishes
Both the residents and businesses of Tübingen have risen to the challenge. "I have stopped stocking any disposable plates," said Naresh Taneja, who has owned vegan Indian restaurant Maharaja in Tübingen for 30 years
"We were already encouraging our customers to bring their own lunchboxes
Yalcin added that the local government provided assistance to deal with the packaging tax and helped them buy dishwashers and reusable cutlery
The ruling has not gone down well with Tübingen's only McDonald's, however, which is suing the city over the tax
With more than 1,500 restaurants across the country
McDonald's claim it's hard to customise solutions and are arguing for a uniform framework as opposed to rules differing across cities
"We agree that the best packaging is the one that is not produced in the first place
But local special paths of individual cities or communities stand in the way of a nationally successful and implementable concept," said a spokesperson
as the company is implementing targeted trials of their own reusables system
Palmer is confident that Tübingen's packaging tax will prevail when the case is heard in March 2022
"We believe that a city has the right to frame such a tax
and then even a big company has to accept that
I can't believe why an international company can't switch to reusables if every small business can do that."
This gives us hope that there might be a way to overcome global warmingPalmer
is credited by many for shaping Tübingen's green policies
such as obligatory solar photovoltaic systems on roofs and the free buses on Saturdays
"We have seen a reduction in the emission of carbon dioxide per capita by 40% in the last 15 years
while Tübingen's economy has grown by 40%," he said
"This gives us hope that there might be a way to overcome global warming and keep growing."
While much can be learnt from Tübingen's model, perhaps it's hard to replicate the city's victories, as they emerge from a uniquely supportive social and political landscape. Some worry Tübingen runs the threat of going too far: a 2011 Spiegel article described the French Quarters
one of the greenest neighbourhoods in the city – and the country – as a "green hell"
presenting its residents as intolerant and hypocritically green
many feel that Tübingen is too academic to be considered a real-world example
"You will stay very much in the academic bubble if you live there," said Kathi Winkler
who lived in Tübingen for several years before moving to Berlin
the example of Tübingen shows that paving the way for a greener planet can be achieved on a small scale
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The Amazon Scout devices were created by Amazon
and roll along sidewalks at a walking pace
currently delivering packages to customers in four states in the U.S.
but will continue to expand to more customers
Our investment in this new Amazon Scout team in Germany
which will consist of dozens of software development engineers and applied scientists
is driven by our partnership with the academic community in Tübingen and made possible by the talented people who live here
We’re now hiring software engineers and applied scientists in the fields of computer vision who are at the forefront of robotics and autonomous systems technology
Establishing a new group for Amazon Scout in Tübingen is another example of Amazon's continued investment in Germany
Amazon Scout joins other teams that form Amazon's innovative Tübingen Development Center
which hosts groups focused on other pioneering areas such as explainable AI
causality and how AI systems can comprehend their environments
the creation of the Amazon Scout team in Tübingen is in line with our plan to further grow the local development center by hiring highly skilled employees
including high skilled jobs in our development centers in Berlin
The University is currently operating under normal conditions
A delegation from UNC-Chapel Hill discussed shared interests and collaboration with the German university’s new president
Leaders at UNC-Chapel Hill and its longtime strategic partner Eberhard Karls Universität Tübingen in Germany are finding new pathways for interdisciplinary collaborations
complex problems demand global partnership and a multidisciplinary approach,” said Chancellor Kevin M
Guskiewicz during a summer visit to Tübingen
“Our partnership is an example of how we’re contributing to society by breaking out of silos and solving the grand challenges of our time.”
Guskiewicz was there with a Carolina delegation that included Vice Chancellor for Research Penny Gordon-Larsen
Vice Provost for Global Affairs Barbara Stephenson and Hussman School of Journalism and Media Dean Raul Reis
The group discussed the universities’ shared interests and collaborations with Tübingen’s new president and other leaders
which included a substantive meeting with Tübingen’s new president
affirmed the strength of the UNC-Tübingen partnership,” Stephenson said
but we are also committed to similar goals for producing research that benefits society.”
the two universities share similarities in size
collaborative approach and research in cancer
“Our shared emphasis on research excellence
innovation and impact transcends disciplines and borders,” she said
The visit coincided with the conference “The Weaponization of Knowledge” and the workshop “Humanities
and Science: Exploring the Power of Narratives.” Both the conference and the workshop were funded by a joint seed fund established in 2022 by Carolina and Tübingen to support interdisciplinary collaborations in data science
“Weaponization” conference organizers included Carolina faculty members Tori Smith Ekstrand (Hussman School of Journalism and Media)
Priscilla Layne (College of Arts and Sciences) and Francesca Tripodi (School of Information and Library Science)
Health and Science” workshop with Carolina English department faculty members Courtney Rivard
“The problems we face in democratic governance worldwide will only be addressed through interdisciplinary dialogue,” Ekstrand said
“This kind of cooperation among colleagues and global partners is essential to defining the problem and addressing it.”
Stephenson sees faculty engagement as a cornerstone of the partnership
“While this partnership has long counted on strong support from university leadership
faculty play a critical role in making our relationship with Tübingen vibrant
This visit has clearly demonstrated their integral involvement,” she said
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a concern after the storm hit western North Carolina
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nearly a thousand Tar Heels got help from fellow students through this free Learning Center program
© 2024 The University of North Carolina at Chapel Hill
A new director establishes the Department of Complex Biological Interactions at Max Planck Institute for Biology Tübingen
focusing on the molecular interactions and coevolution between carnivores and their prey
Yen-Ping (“Ping”) Hsueh heads one of the sixth Departments at the Max Planck Institute for Biology Tübingen
the institute expands its expertise in molecular mechanisms in evolutionary biology
“We are thrilled that Ping is joining us,” said Ruth Ley
the Managing Director of the Max Planck Institute for Biology Tübingen
“She brings an exemplary international research record
and a perfect fit with the institute’s research goals of advancing the knowledge of evolutionary biology.”
At the Max Planck Institute for Biology Tübingen
Hsueh will lead the Department of Complex Biological Interactions
focusing on understanding the cross-kingdom predator-prey interaction and co-evolution between carnivorous fungi and nematodes
Hsueh and her team’s research will significantly advance our understanding of the biology of nematode-trapping fungi such as the oyster mushroom
Their work seeks to answer how carnivorism arose in the fungal kingdom
and to open new avenues for developing biocontrol methods and novel treatments for parasitic nematode infections in the long term
Her research also aims to understand how the model nematode C
elegans senses and responds to fungal predators and to unveil the secrets behind the predatory mechanisms and evolution in the fungal kingdom
Yen-Ping Hsueh was born in Taipei and received her undergraduate and master’s degrees at the National Taiwan University
majoring in Plant Pathology and Microbiology
she joined the Department of Molecular Genetics and Microbiology at Duke University
for her PhD and stayed on as a postdoctoral fellow under the guidance of Dr
she studied the genetics and evolution of the sexual cycle and the mating-type locus of the human fungal pathogen Cryptococcus neoformans
where she worked as a postdoctoral fellow in Dr
investigating the predatory-prey relationship between Caenorhabditis elegans and the nematode-trapping fungus Arthrobotrys oligospora
Yen-Ping Hsueh established her independent laboratory at the Institute of Molecular Biology
Hsueh received the Taiwan Outstanding Women in Science (TOWIS) 2022 Award in the Most Promising Young Scientist category and is a member of the EMBO Global Investigator Network (GIN) and Young Investigator Program (YIP)
dateFormat['de_DE'])+ ' - '+item['institution']+'
Weitere Pressemitteilungen dieser Einrichtung
On behalf of the iFIT spokespersons Lars Zender
it is our pleasure to inform you about and invite you to the next episode of our iFIT Seminar Series 2024 that will take place
at Big Lecture Hall in the CRONA (Hoppe-Seyler-Straße 3
“Dynamics and Structure of Engineered Immune Synapses”
Adoptive cell therapy using chimeric antigen receptor (CAR) T cells has shown unprecedented efficacy in treating hematological malignancies
such as relapsed/refractory B cell lymphomas
challenges remain in improving long-term responses
and expanding the use of CAR T cells to a broader range of hematological malignancies and difficult-to-treat solid tumors
Achieving these goals requires a deep cellular and molecular understanding of how CAR designs influence three essential aspects of their function: 1) the dynamics of CAR T cell-tumor cell interaction at the immune synapse
and 3) the mechanisms of target cell killing
The group surrounding Benita Wolf has developed a novel super-resolution microscopy technique
to study the native ultrastructure of CAR T cell-target cell interactions— a first in the field
they mapped the nanoscale architecture of physiological and engineered immune synapses and found that CARs with different co-stimulatory molecules varied in immune synapse actin architecture
their work explores the impact of CAR designs on CAR T cell short- and long-term efficiency
All members of the University Hospital and University of Tübingen are invited to participate
We look forward to this Seminar Series session and to see you there
Cooperation for transparency and quality in healthcare
Stern: Germany's Outstanding Employers in Nursing 24/25
Subsidies from the Hospital Future Fund financed by the European Union
© 2025 University Hospital and Faculty of Medicine Tübingen
the mayor of Germany’s southwestern city of Tuebingen
2023 that he was taking some “time out” after coming under fire at the weekend for using a racist slur at a conference
BERLIN (AP) — The mayor of Germany’s southwestern city of Tuebingen said Monday that he’s taking some “time out” after coming under fire over the weekend for using a racist slur
Boris Palmer also said he’ll resign from the Green party following criticism over his repeated use of a racist term for Black people at a conference Friday
which prompted some attendees to walk out in protest
Palmer then repeatedly used the racial slur and suggested he was being victimized
“If someone uses the wrong word then they’re a Nazi to you,” he told the activists
and suggested that this reputation would stick with him like “the Star of David” that Jews were forced to wear during the Third Reich
Palmer apologized to “those I’ve disappointed” and said that a mayor “should never speak that way.” The 50-year-old
added that he’s “incredibly sorry” at having given the impression that he downplays the significance of the Holocaust
Palmer said he would seek “professional help” to prevent himself from reacting inappropriately when he feels unjustly attacked in the future
Palmer was first elected mayor of Tuebingen
in 2006 and won re-election running as an independent last year
Under the University’s Excellence Strategy
the Department of Population-Based Medicine hosted a workshop in collaboration with colleagues from the University of the Witwatersrand (a strategic partner located in Johannesburg
we developed an interdisciplinary project proposal aimed at addressing stress factors and coping mechanisms in teachers
These two distinct settings will offer a rich context for comparison
and we are excited to move forward in realizing the ideas generated during the workshop
We hope that the project will have meaningful real-world implications for teachers
including training programs and policy applications
Photogallery
is designed to specifically bind to two different proteins located on different cell types
One protein is located on the surface of immune cells
The other protein is found on tumor cells as well as in the surrounding tissue and blood vessels
which means that both structures can be specifically targeted by the antibody
🤞 The researchers hope that this dual effect will be particularly effective in combating the tumor
🎯The aim of the clinical trial is to test the safety and efficacy of the antibody in patients with metastatic cancer of the upper gastrointestinal tract
breast and sarcoma.👏 Congratulations Juliane on this great recognition
🍀 Wishing you and your team much success with conducting the clinical trial
The Measures give an overview of all research activities in the FONA Strategy
international cooperation and research infrastructures
The NETPEC concept envisages using artificial photosynthesis to extract CO2 from the atmosphere and convert it into products that can be stored over the long term
An initial process is being developed and tested for efficiency and usability
If negative emissions have to be realized on the scale that is currently emerging
aspects such as long-term storability and land consumption will become very important in addition to costs
The artificial photosynthesis approach investigated in the project allows
to minimize land consumption and associated challenges
CO2 is converted into another substance using energy from sunlight
The choice of the photoelectrochemically generated product can be adapted to the storability
oxalate and coal flakes are investigated first
the NETPEC project scrutinizes which of the products have the greatest potential in terms of long-term
safe storability and what conversion efficiencies can actually be achieved
adapted catalysts and solar cells are developed and combined to form a photoelectrochemical carbon sink
the climatic conditions will be modeled and the sustainability of the entire process chain will be evaluated
The project will allow a first assessment of whether and to what extent photoelectrochemical approaches could be a useful complement to the methods of terrestrial carbon dioxide removal that have been mainly investigated so far
Matthias MayUniversität TübingenAuf der Morgenstelle 15
Phone: +49 7071 2976232Email: matthias.may@uni-tuebingen.de
Geo- und UmweltforschungszentrumSchnarrenbergstraße 94-96
Phone: +49 7071 2974791Email: kira.rehfeld@uni-tuebingen.de
NETPEC homepage
Carolina and Eberhard Karls Universität Tübingen in Germany are jointly pursuing how to use academic partnerships to address data science challenges.
UNC-Chapel Hill is deepening inroads with its longtime strategic partner Eberhard Karls Universität Tübingen in Germany as the two universities jointly pursue how to best use academic partnerships to address global challenges.
As part of this visit, Stephenson invited Stan Ahalt, inaugural dean of the School of Data Science & Society to join.
“Tübingen is a German University of Excellence and a leader in machine learning and data science,” said Stephenson. “And we spotted an opportunity to connect Dr. Ahalt with experts not only in data science research but administrators of data science programs and graduate students with interests related to data science as part of the Royster Conference.”
Ahalt joined conference sessions and attended meetings with Stephenson and Tübingen leadership to discuss their efforts on data science. According to Ahalt, he found inspiration in Tübingen’s approach that he plans to implement in Chapel Hill, and the student discussions have already informed his thinking as he prepares for the 2023 launch of the School of Data Science & Society.
“In many ways it was the perfect trip to take at just the right time,” said Ahalt.
Over the past year, while international travel was limited due to the pandemic, Carolina and Tübingen held a series of virtual meetings between university leaders, research offices and faculty to keep the relationship strong. Participants explored shared academic strengths and goals, and through these conversations, teams from both institutions hypothesized that they could have greater impact by working together.
“Around the world Carolina is known for being good at collaboration, a place where researchers can reach across silos and come together on work that benefits society,” said Stephenson. “Our partners at Tubingen share that core value, as manifested in the cluster of excellence focused on machine learning, and this visit reinforced a commitment to closer collaboration to solve global challenges.”
Carolina and Tübingen are incentivizing joint research projects through a newly created seed fund. Together the Office of the Vice Provost for Global Affairs (OVPGA) and UNC Research have established a fund with Tübingen to support interdisciplinary collaborations in the fields of data science and health, data science and democracy, and data science and urban planning. The OVPGA is currently accepting applications for funding on a rolling basis.
Scholars from across multiple disciplines and both institutions will gather in Tübingen next summer for a workshop to discuss how to study the weaponization of intellectual thought and its impact on democratic processes. Following the workshop, the group will begin gathering data and will collectively seek funding for further joint research initiatives.
The OVPGA will continue to support faculty interested in collaborating with Carolina’s international partners to address global challenges. As part of this experience at Tübingen, Ahalt will be able to apply what he’s learned to address global challenges through the School of Data Science & Society.
“Global challenges, like climate change and health as an example, are going to require international dialogue,” said Ahalt. “What we need to do from a scholarly perspective is to be able to motivate our networks of scientists, humanists, researchers and have a dialogue that persists long enough that we can actually solve problems.”
This visit not only paved the way for new ideas and new global collaborations. It also led Ahalt to deepen his appreciation for the Carolina community.
“This experience makes me more and more proud to be part of this wonderful University.”
For more information about Carolina’s collaboration with Tübingen and to inquire about joint seed funding, contact Melissa McMurray (melissa_mcmurray@unc.edu), OVPGA associate director of global partnerships.
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Want more Carolina news? The Well newsletter updates Tar Heels on UNC-Chapel Hill’s top stories, upcoming events and campus accolades, arriving in your inbox every Tuesday, Wednesday and Thursday morning.
NC Children’s will be North Carolina’s first freestanding hospital dedicated to caring for kids.
The Carolina sophomore shares her life through her poems, tours and activities on campus.
Text by David Kasparek. In the Swabian city of Tübingen, the Stuttgart-based office VON M has completed the new headquarters for the municipal housing company GWG, which is both a homogenizing urban building block and a contemporary architectural flag ship for the client.
The surroundings are heterogeneous. It takes a quarter of an hour to walk here from the train station and you find yourself between a branch of a retail group, two-story turn-of-the-century houses with mansard roofs, and three-story post-war modernism.
Courtesy of VON MHere, on Eisenbahnstrasse, GWG has set up its new company headquarters. The company builds, sells, rents, and manages residential buildings. The design for the company's new flagship building was created by Stuttgart-based VON M. The architects' maxim was to translate the company's contemporary self-image into an appropriate architectural form and functional spaces.
the VON M team has ensured that the local housing company has an architectural calling card that reflects its own vision but does not egotistically occupy a space in the city
Coupled with carbon dioxide-binding materials
the building represents a contemporary approach to architecture
The way in which it stands as an unpretentious cube in the urban space
consciously and thus literally withdrawing from the actual address in terms of urban development and thus creating something for the microclimate and the general public
and not timeless idea of what architecture can be today
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- The new science lab’s focus is to research fair
and explainable Artificial Intelligence (AI)
- The Lablet aims at establishing a culture of sharing research results in the form of publications
- To build trust in AI and to serve the public
the science team’s aim is a steady interchange with science
- AI research in the Lablet follows a curiosity-driven approach
which gives scientists full freedom of choice
2019 – Amazon announced to establish a Lablet in Tübingen
a new kind of research center that is dedicated to the open research in Artificial Intelligence (AI) and its applications to work on long-term challenges in AI
will conduct fundamental research in the field of AI
Their particular interests are explainability
causality and research on AI that comprehends its environment
To foster scientific progress and reproducibility
the Lablet team will strive to share the research in the form of publications
The research is curiosity-driven instead of aiming at incrementally improving products and applications
The freedom of research and above all the freedom to choose what to scientifically examine are only the first two steps towards an unbiased
fair and open AI,” said Bernhard Schoelkopf
scientific advisor of the Tübingen Lablet and director at Max Planck Institute of Intelligent Systems
“Another important step is a steady interchange with science
We are convinced that AI should serve the public
we must build trust in AI – and we can only succeed if we make AI as transparent and understandable as possible.” Amazon plans to establish more Lablets to conduct fundamental research in AI worldwide
Focus on exchange with scientific and local communities
Research in Artificial Intelligence in the Tübingen Lablet will focus on the following areas: causality and explainability
The choice of location is also based on this substantive focus
As a globally renowned research location in Germany
Tübingen and the local Cyber Valley initiative are characterized by a lively and reflective debate culture
Amazon harnesses this potential to let both the scientific community and the public participate in the Lablet research
The research center welcomes an open dialogue and lively discussions with leaders from politics
“Amazon prioritizes long-term results over short-term benefit
which is exactly what we need for curiosity-driven
Operative Head of the Amazon Lablet in Tübingen
we want to understand AI and make AI understand its environment
Our goal is to empower humans to question and explain data-based decisions
and to provide causal explanations for an algorithm’s behavior.” As part of its local commitment in Tübingen
Amazon has a close collaboration with the Max Planck Institute for Intelligent Systems and the University of Tübingen
this collaboration is open to scientists from other institutions
New building for the Amazon research center
Amazon announced to open a research center in Tübingen and to create jobs for 100 high-skilled employees
The company also joined the Cyber Valley initiative
which brings together international key players from science and industry to concentrate their research activities in the field of AI
The Tübingen site is the fourth Amazon Research and Development Center in Germany after Berlin
The new Lablet will be part of this Amazon Research Center in Tübingen
the city council of Tübingen approved the sale of land adjacent to the Max Planck Institute for Intelligent Systems to a developer
Amazon will lease this building to set it up as its new research center in Tübingen
The building was planned according to the requirements of the municipality as well as local Amazon research teams
all of which will be accessible to the public to foster scientific exchange and discussion with local communities
Amazon is guided by four principles: customer obsession rather than competitor focus
and Alexa are some of the products and services pioneered by Amazon
visit amazon.com/about and follow @AmazonNews
Combining PET and MRI techniques can provide a more detailed view of the molecular and functional changes in tumours.Credits: University Hospital Tuebingen / Beate Armbruster
Science has made great strides in treating cancer
yet many tumours eventually become resistant to therapy
The Image-guided and Functionally Instructed Tumor Therapies (iFIT) Cluster of Excellence at the University of Tübingen
Founded in 2019 with a grant from the German Research Foundation (DFG)
iFIT is the only oncology cluster of excellence in the country
The group unites three key areas of cancer research: functional target discovery and molecular therapies
By bringing these fields together under one institutional roof
the cluster aims to generate new insights on the biological processes within tumours
informing the development of therapies that target weak points and help keep resistance at bay
“We realized we’re in a unique situation,” says Lars Zender
that all three disciplines are pursued at such a high level in the same place
“With teams working at the boundaries of these areas
you can really do holistic translational cancer research.”
Functionally instructed molecular therapy is Zender’s area of expertise
They use technologies such as RNAi and CRISPR to screen tumours for new therapeutic targets
The university’s strong medicinal and pharmaceutical chemistry departments mean their findings are being translated into new experimental treatments
led by iFIT co-founder Hans-Georg Rammensee
who researches personalized peptide vaccines for cancer patients
The cluster also develops bispecific antibodies
which direct T cells to specific targets on malignant cells
which combines imaging methodologies to unlock new molecular insights
the university has a long track record — PET-MRI
The cluster now has its own pipeline for PET imaging tracers
targeted molecular labels that can reveal features such as metabolic activity within a tumour
including professorships and new independent research groups
to foster innovation at the interface between these three disciplines
It has attracted high-flying lab heads from around the world
a cell biologist specialising in microscopic imaging technologies
“I was able to build this infrastructure of microscopic imaging and integrate it with the macroscopic imaging.”
Combining PET and MRI techniques can provide a more detailed view of the molecular and functional changes in tumours.Credit: University Hospital Tuebingen / Beate Armbruster
Weigelin is using her expertise in microscopic imaging of the behaviour of immune cells within tumours to create a bridge between fundamental cell biology and larger-scale clinical imaging
Her work helps clinicians decode what their images are revealing about tumour behaviour
"We can go from the sub-cellular scale to the whole body of a mouse in preclinical imaging,” says Weigelin
“We’ve already translated some of the new PET tracers to the clinic and they have been used successfully in patients.”
One such tracer identifies a treatment stress response in tumour cells called senescence
Senescent tumour cells secrete factors involved in therapy resistance and being able to target them could transform cancer treatment
iFIT's molecular therapies team is already pursuing this and other tumour stress responses
To find out how you can contribute to the groundbreaking research being done at the University of Tübingen’s iFIT Cluster of Excellence, visit us here.
a global pioneer in the production of green and renewable hydrogen
has built and will operate a green hydrogen production plant for Deutsche Bahn in Tübingen
The electrolysis plant in the innovation hub of DB Energie
has an annual production capacity of up to 30 tons (installed electrolysis capacity of 1 MW)
The green electricity comes from Deutsche Bahn’s green electricity portfolio
DB Energie is testing new technologies for sustainable rail energy supply
including in the “H2goesRail” project
a climate-neutral hydrogen train will be put into operation this year on a test route in Baden-Württemberg – between Tübingen
“This project demonstrates the economic viability of hydrogen solutions in the transport and mobility sector
Sustainable energy sources and innovative technologies are needed to decarbonize the transport sector
One of these technologies is hydrogen-powered trains
which are a clean and efficient alternative to conventional diesel-powered trains as they are virtually CO2-free
The H2goesRail project is a pioneer in the field of passenger and freight transportation,” says Luc Graré
Head of Central and Eastern Europe at Lhyfe
Lhyfe wants to gain experience for a largely autonomously operated system
as well as the direct coupling of hydrogen production with a filling station on a large scale
The commissioning of the complex system with its many different dynamics
Lhyfe is taking on this challenge in order to provide Deutsche Bahn and subsequent partners with a hydrogen production plant that can be used to test the integration of green hydrogen production into customer processes
Lhyfe develops customized solutions throughout Europe for the construction of local production and distribution systems for green hydrogen
The site in Tübingen is Lhyfe’s first plant in Germany
Another 10 MW plant is currently being built in Schwäbisch Gmünd
which will produce up to 4 tons of green hydrogen per day
Lhyfe aims to become a major player in the mobility and industry sector
through customer deliveries in tube trailer (bulk) in France and Germany by 2025
Several other sites throughout Europe are already under construction or being expanded
Lhyfe has been operating its first green hydrogen site in France since the second half of 2021
and two other sites were opened in France in 2023
Click to access the Lhyfe Media Kit (press releases and visuals)
Lhyfe inaugurated the first industrial-scale green hydrogen production plant in the world to be interconnected with a wind farm
it inaugurated the first offshore green hydrogen production pilot platform in the world
and currently has several sites under construction or expansion across Europe
Lhyfe is represented in 12 European countries and had 195 staff at the end of December 2023. The company is listed on the Euronext market in Paris (ISIN: FR0014009YQ1 – LHYFE). Lhyfe.com
Click to access the Lhyfe Media Kit (press releases and visuals)
We are pleased to recognize the outstanding achievement of Sophia Kieferle
who was recently awarded the MoBBEL Prize of the Tübingen Biochemists for outstanding master's theses
In her master's thesis in Professor Schindler's working group
Sophia dealt with the BioNTech corona vaccine
she treated primary cells such as connective tissue cells
vascular cells and muscle cells with the mRNA vaccine from BioNTech
The different cell types serve as a model to replicate the most important cells at the vaccine injection site
Sophia then investigated how much spike protein the cells produced and whether the spike protein is incorporated into extracellular vesicles
We congratulate Sophia Kieferle on this great achievement and wish her continued success on her scientific path
Elekta Unity combines advanced diagnostic standard MR imaging and precision radiotherapy technologies
giving doctors the “vision” to zero in on tumors and avoid healthy tissues
the radiation oncology department at Tübingen University Hospital introduced its new Elekta Unity MR-linac
a groundbreaking cancer treatment system that integrates two critical but distinct technologies in a single platform: a state-of-the-art
high field wide bore 1.5 Tesla MR imaging system and a next-generation linear accelerator
This new technology enables clinicians to confidently see and track the target during treatment and respond accordingly
personalizing therapy for each patient every time they are treated
“Elekta Unity ushers in a new level of personalized patient care in radiation therapy,” said Richard Hausmann
“We are pleased to celebrate with Tübingen University Hospital as they prepare to bring our shared vision of transformative cancer therapy to their patients
prolonging and saving lives and to supporting our customers as they work with patients every day to achieve these critical goals.”
“Elekta Unity will give our clinicians the ability to see crystal-clear
high-field MR images while the radiation is being delivered
Tumors and surrounding tissues can be located and their movement monitored with accuracy at the time of treatment
This allows treatment plans to be adapted while the patient is on the table in response to changes in tumor position
biology and the relationship to sensitive organs over time,” says Daniel Zips
Professor Radiation Oncology at Tübingen University Hospital
“We expect that this enhanced real-time visualization of cancer targets will allow us to avoid healthy tissue as much as possible during the delivery of therapeutic radiation
leading to improved outcomes for cancer patients and positioning Unity as a truly unique way to treat cancer.”
The hospital imaged the first patients with the 1.5 T MR imaging system and calculated the first MR-based treatment plans on June 19 when the Unity CE mark was issued
Tübingen University Hospital expects to use Elekta Unity to treat a wide range of cancers and potentially enable new therapeutic options for hard-to-treat cancers with anatomies that require high-field imaging to effectively distinguish the tumor from nearby healthy tissues and organs-at-risk
This allows anatomical structures that previously were deemed unsuitable for radiotherapy to be considered for treatment and gives the care team greater flexibility in their approach to radiation therapy
It also ensures each patient receives optimal care based on individual tumor characteristics every time treatment happens
“It was exciting to showcase Elekta Unity during the open house,” added Dr
Chair Research Section Biomedical Physics at Tübingen University Hospital
“We are especially proud to serve this community
advanced technology that will potentially transform how we treat individuals with cancer.”
Elekta Unity has CE mark but is not available for commercial distribution or sale in the U.S
https://www.elekta.com
Posted in: Device / Technology News | Medical Condition News
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Leaders at UNC-Chapel Hill and its longtime strategic partner Eberhard Karls Universität Tübingen in Germany are finding new pathways for interdisciplinary collaborations
A Carolina leadership delegation including Chancellor Kevin Guskiewicz
Vice Chancellor for Research Penny Gordon-Larsen
Vice Provost for Global Affairs Barbara Stephenson
and UNC Hussman School of Journalism & Media Dean Raul Reis
recently traveled to Tübingen to continue discussions on the universities’ shared interests and collaborations with Tübingen’s new president and other leaders
affirmed the strength of the UNC- Tübingen partnership,” Stephenson said
collaborative approach and areas of research strength including: cancer
“We’ve identified many complementary research areas that benefit from this collaboration and our mutual desire to address the most pressing global challenges,” she said
innovation and impact transcends disciplines and borders.”
The visit coincided with the conference “The Weaponization of Knowledge” on the shared concern of “the misuse
manipulation and reappropriation of knowledge for anti-democratic purposes.”
The organizers included UNC-Chapel Hill faculty members Tori Smith Ekstrand (Hussman School of Journalism and Media)
Priscilla Layne (Department of Germanic & Slavic Languages & Literatures)
and Francesca Tripodi (School of Information and Library Science)
and Guido Zurstiege from Tübingen’s Institute for Media Studies
Twenty-one graduate students and faculty members from six institutions joined the conference
“‘The Weaponization of Knowledge’ is an outgrowth of a variety of social
political and economic factors; the problems we face in democratic governance worldwide will only be addressed through interdisciplinary dialogue,” Ekstrand said
Both the conference and the workshop were funded by a joint seed fund established by Carolina and Tübingen in 2022
which supports interdisciplinary collaborations in data science
Carolina’s portion of the fund is provided by the Office of the Vice Provost for Global Affairs and the Office of the Vice Chancellor for Research
complex problems demand global partnership and a multidisciplinary approach,” Guskiewicz said in welcome remarks at the conference
As the universities continue to identify areas of collaboration across multiple disciplines
faculty play a critical role in making our relationship with Tübingen vibrant; this visit has clearly demonstrated their integral involvement,” she said
“They are highly engaged in collaborative research and teaching with international partners
and the Office of the Vice Provost for Global Affairs is here to support them as a facilitator
Applications for the joint seed fund will open soon. Subscribe to the UNC Global Affairs newsletter to receive updates
Many law students spend their summers working at a firm or doing research with a professor, but five students were selected to spend two weeks in Tübingen, Germany, with UNC School of Law Dean Martin H. Brinkley ’92, Professor Lissa L. Broome and Professor John F. Coyle as part of a new study abroad program
Through research workshops and courses, the Tübingen-Chapel Hill Law Program facilitates trans-Atlantic collaboration among students through a strong teaching component designed to promote mutual understanding of each other’s legal systems and cultures
Andrew Wisniewsky 2L and Carleigh Zeman 2L visited the Eberhard Karls University Faculty of Law July 1-12 to take courses—taught in English—alongside German students
They studied issues relating to corporate law
and participated in excursions to institutions like the Court of Justice of the European Union in Luxembourg and the European Central Bank headquarters in Frankfurt
The UNC students also had the opportunity to explain U.S
law and legal institutions to German law students
Professor Jonas Monast, director of Carolina Law’s environmental law center
also visited Tübingen in June to cohost a workshop on energy transitions in federal legal systems with scholars from Germany
The UNC Center for Banking and Finance
offered each student a stipend to defray the costs of travel and housing
One of those stipends was funded through an endowment for the center established by the law firm Williams Mullen
which was supplemented by a personal gift from Williams Mullen attorney Camden Webb ’95
Students will speak about their Tübingen experience at the August meeting of the center’s board of directors
will not scrap its formal name despite calls for the change - Count Eberhard Im Bart was a virulent 15th-century antisemite who expelled all the Jews living in the city
Rob Hyde
3 min read A leading German university has voted to keep the name of a notorious antisemite as part of its official title —prompting fury among students and Jewish groups
made the decision not to scrap its formal name despite calls for the change
Count Eberhard Im Bart was a virulent 15th-century antisemite who expelled all the Jews living in the city and surrounding area
vice-president of the Jewish Student Union of Germany (JSUG)
told the JC the university’s decision was “utterly disappointing”
the commissioner against antisemitism for the state of Baden-Württemberg
Ms Veiler said: “Of course we respect the fact that it was a democratic decision
“We find it so disappointing that the university had the chance to change this situation and to set an example
“We realise that you cannot just change a difficult past
but it had the opportunity to draw the right conclusions
Here the university has just failed.” In a written statement to the JC
Mr Blume said: “The fact that the senate of my alma mater did not even listen to me before making its brief and wrong decision
despite my letter of support for the Jewish students
unfortunately speaks for itself.” Founded in 1477
the university is internationally renowned
In the hope of ending a decades-long controversy over its name
it commissioned a six-strong team of expert historians to determine the extent to which Count Eberhard could be deemed antisemitic
The investigation was led by Sigrid Hirbodian
director of the Tübingen Institute for Regional History
who concluded in her report: “Eberhard is hostile to Jews and thus in no way differs from the vast majority of his contemporaries and peers.” The university senate then voted 16-15 to keep the name
As a two-thirds majority was needed to change the title
the university will continue to be called the Eberhard-Karls-Universität Tübingen
Mr Blume said: “I consider the present report on the exculpation of Count Eberhard im Bart to be historically one-sided and weak and assume that there will be a new vote on renaming in just a few years
Nobody should have to study at a university that is named after a Jew hater
Jew expeller and public adulterer.” He suggested to the university’s rector
that the university should be renamed after Eberhard’s mother
Students have campaigned since the 1970s to rename the university
Ms Veiler wrote in the Jewish newspaper the Jüdische Allgemeine last year: “How is it possible that with all the lip-service German politicians repeatedly claim to have learned from history
Jewish students still have to go in and out of institutions named after staunch antisemites
And how can it be that the discourse on this is conducted so far away from the students
“We cannot and will no longer tolerate the unwillingness of German institutions to stand by their antisemitic past.” Another name proposed is that of Ernst Bloch
a Jewish Marxist philosopher who died in 1977 and remains a popular figure with radical students
Flags bearing the legend “Ernst Bloch University Tübingen” are a familiar site at left-wing protests
some Jewish students want the name to remain the same
board member of the Jewish Student Association for the Region of Baden
told the JC: “The JSUD (Jüdische Studierendenunion Deutschland) started a large-scale campaign last year: ‘Remembering means changing.’ “But we say changing does not mean deleting and erasing
this opportunity for a necessary confrontation with the person is thereby completely taken away
He posted on Facebook: “The demand for this clearly stems from woke cancel culture
The evidence for Eberhard’s antisemitism is by no means drastic in the context of the time.” Despite repeated attempts by the JC
changed its name to the Berlin University of Applied Sciences and Technology because of the antisemitic history of 19th-century Prussian statesman Christian Peter Wilhelm Beuth
Germany
Antisemitism
signed a new Memorandum of Understanding and announced the new round of joint investment during a trip to Tübingen
She was joined by our Pro-Vice-Chancellor (Global)
Professor Claire O’Malley and our Executive Dean for Arts and Humanities
A long and proud history of collaboration
Formalised by a Memorandum of Understanding signed in April 2017
our relationship with the University of Tübingen is one of Durham University’s flagship strategic partnerships in Europe
It dates back to 1989 and builds on a successful track record of student exchanges
a precedent for research collaboration and membership of the Matariki Network of Universities.
There is a long history of collaboration between Durham and Tübingen
Durham City Council has been twinned with the city of Tübingen since 1969
took part in a DCC student exchange with a family in Tübingen.
Durham and Tübingen have student exchange agreements in Chemistry
A partnership for mutual benefit
When the strategic partnership was established
it was agreed that the senior leadership teams of both institutions would take part in delegation visits on a regular basis to allow senior colleagues to develop a close working relationship with their counterparts
They could learn more about the partner institution
The visits would also provide the opportunity to explore issues pertinent to the senior leadership at both universities. Durham and Tübingen colleagues would also share updates on key institutional developments and priorities
Delivering impact through research collaborations
A key part of the institutional relationship between Durham and the University of Tübingen has been a mutual commitment to supporting joint research projects
These have been selected and funded through a joint Strategic Development Fund.
both institutions have invested €150,000 per partner in support of collaborative projects
we have secured a £970k grant from the Biotechnology and Biological Sciences Research Council on the topic of plant immunity and a £250k European Commission Archaeology Grant focusing on Climate
An additional collaboration between Durham and Tübingen archaeologists resulted in a successful joint seedcorn project “Death and Demographics: Comparing Settlement and Burial Records in the Ancient Near East”
This collaboration secured a £1m European Research Council grant to fund Durham’s work with Tübingen
on the use of remote sensing and GIS techniques in archaeological analysis.
Working together to address global challenges
The fourth call of the fund was launched on 22 January 2024 with a deadline of 17 May 2024
The priority themes for this call will be:
This additional investment will not only benefit Durham and Tübingen
but also the wider society and economy in the UK and Germany
Both institutions look forward to enhancing further this partnership through the seedcorn fund.
The Palatine CentreDurham UniversityStockton RoadDurham DH1 3LE
Our weekly email is chockful of interesting and relevant insights into Jewish history
When members of the Protestant TOS church in Tuebingen began to investigate the hidden Nazi history of their city and their own families they were in shock
“Many were horrified to discover that their fathers and grandfathers had been actively or passively involved in the Holocaust as SS guards
civil servants or in other capacities,” explains Claudia Kiesinger
had been unaware of any personal connection to the Holocaust
Although she had seen photos of her maternal grandfather in his army uniform
she assumed it was a closed chapter in Germany’s history
When encouraged to explore their families’ hidden past
Pfeiffer was shocked to discover that her grandfather
Pfeiffer was shocked to discover the terrible family secret that her paternal grandfather
It took weeks for her to come to terms with that horrific realization
Then in 2012 she traveled to Auschwitz with her church and addressed a group of Holocaust survivors
“I wanted to speak the words that my grandfather never spoke
he told his family what he had done and said
nobody must know.’ And so the whole story remained a secret,” explained Pfeiffer
At the end of the war near the city of Tuebingen there had been eight concentration camps well-known for their cruelty and high death rate
In April 1945 the surviving inmates were sent on brutal death marches to Dachau
Along the way thousands were shot in front of German civilians
Survivors and their descendants walked side by side with the descendants of Nazi perpetrators
the first March of Life took place in April
following the same route through the German countryside
Holocaust survivors and descendants of survivors from the United States joined the March
walking side by side with the descendants of Nazi perpetrators
started by Jobst and Charlotte Bittner and members of TOS Church in Tuebingen
is now an independent organization though still affiliated with the church
In 2018 almost 60 Marches of Life took place worldwide ranging from small Marches in Ueckermünde
Germany with 40 participants to the large March of the Nations in Jerusalem that had 6000 participants
Approximately 20,000 people ventured into the streets with a March of Life in over a hundred cities and towns all over Germany including Heidelberg
Marches have been held in other countries like Romania
Claudia Kiesinger feels there has been an overall positive response to Marches of Life in Germany
“The message about looking into the history of one’s own family concerning the Nazi era is a challenging concept but something that every German can relate to
Occasionally there is criticism that March of Life is connecting remembrance with a clear pro-Israel stance or asking “Why do we still have to talk about the Holocaust?”
In 2015 the organization established a house in Caesarea for Holocaust survivors with weekly gatherings and a luncheon
“Each time both the survivors and the descendants of Nazis share their stories
It is a very emotional experience and sometimes not easy but new friendships are always formed,” explains Kiesinger
An emotional moment for a Holocaust survivor and the descendant of a Nazi
Sometimes special encounters take place such as one last June between Berta Feinstein and Riva Leibovich who had known each other in the ghetto of Mohyliv-Podilskyi in Ukraine
Berta was 13 years old when she came to the ghetto with her family in 1941
Riva's mother asked Berta to take care of her little daughter
the two girls lost all contact with each other
Berta graduated from Kiev University with a degree in Russian Literature and Linguistics and became a teacher in Minsk for 40 years
recognizing and excitedly hugging each other in the March of Life house
the March of the Nations brought 6000 people from 50 nations to the streets of Jerusalem on the 70th anniversary of the State of Israel
Its motto: MiShoah LeTkuma – from Holocaust to New Life
2019 the March of the Nations will take place in a condensed format in different cities throughout Israel
The March of Life has been honored by the Israeli Knesset for its special efforts on behalf of Holocaust survivors
The March of Life is also involved with sending volunteers on a regular basis to ALEH Negev
“The idea is practical reconciliation: the descendants of Nazis serving the weakest members of Israeli society.”
“The idea is practical reconciliation: the descendants of Nazis serving the weakest members of Israeli society
We have had several exchange and encounter programs with schools in Ashdod and other cities and also a special encounter in Yad Vashem of members of the Krembo Wings Youth movement and young people from Germany
Poland and other nations,” says Kiesinger
When asked about the organization’s response to the disturbing rise in anti-Semitism in Europe
“We believe that the most effective way to combat anti-Semitism today is to learn from the past by confronting the unfortunate anti-Semitic history in a personal way
relating to the mostly hidden family histories in Germany concerning the Nazis
Also in other European countries like Austria
France and Switzerland there was collaboration and sympathizing with the terrible acts committed during the Holocaust
We are continuing to call and train people to do annual Marches of Life in their own cities
to lift a relevant voice for Israel and against modern anti-Semitism and to keep organizing Marches ourselves.”
Born in South Africa and raised in Canada, Menucha Chana Levin B.A. M.Ed. has lived in Jerusalem with her family for over twenty years. The author of five novels, her latest book is Hidden Heritage about international adoption in Jewish families
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Science of the Total EnvironmentCitation Excerpt :16 EPA Polycyclic aromatic hydrocarbons (PAHs) summed up to 2.9 mg/kg dry weight almost exclusively shared by high molecular weight PAHs
indicating a strong impact by traffic exhaust and combustion origin (Tobiszewski and Namieśnik
Recent studies highlighted that traffic-borne air particulate matter carries considerable loads of PAHs and traffic-related metal contamination
which we assume to contribute via urban surface runoff to the overall contamination load of the sample in addition to road runoff (Jandacka and Durcanska
the mineral oil index revealed a total oil concentration of 0.6 %
which also confirms the strong traffic impact of the urban and road runoff particulate matter retained in the sedimentation basin
Journal of Contaminant HydrologyCitation Excerpt :The channels span 140 km in total
and the sampling station was located near the end of the channel
with an average width of 7 m and a height of 4 m
The basin is heavily urbanized and populated
and experiences high traffic from both light and heavy vehicles as well as motorcycles
with over 20 million daily trips estimated from 4 million vehicles and 3 million motorcycles in Tehran (Nasrabadi et al.
The length of this channel and its tributaries is about 140 km
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Institutul de Cercetare al Universității din București (ICUB) vă invită la cel de-al 38-lea seminar ArchaeoSciences
de la Universitatea din Tübingen va susține prelegerea intitulată „Sinagovtsi on Vidbol and its importance for the study of the contacts along the Middle and the Lower Danube during the Early Neolithic period”
Evenimentul va avea loc în data de 3 aprilie 2025
Această ediție a seminarului se concentrează pe o descoperire arheologică de excepție din Bulgaria
Proiectul recent de construcție de la Sinagovți
situat pe râul Vidbol – un afluent sudic al Dunării în apropiere de Vidin – a scos la iveală un sit neolitic ce conține o groapă mare (cu suprafață de aproximativ 18 metri pătrați) și un șir de trei schelete: un bărbat adult
toate aflate la circa trei metri sub nivelul actual al solului
Cei doi adulți au fost înhumați în interiorul gropii
în timp ce copilul a fost depus în exterior
Modul de înhumare a fost diferit pentru fiecare individ: unul a fost așezat în poziție dorsală
Deasupra scheletelor au fost depuse oase de animale
Sincronizarea umpluturii gropii și a mormintelor este susținută de datarea radiocarbon directă a oaselor umane și animale
Având în vedere numărul redus de situri neolitice timpurii cercetate în nord-vestul Bulgariei
descoperirea de la Sinagovți oferă un potențial semnificativ pentru analize multi-proxy
Acestea urmăresc corelarea practicilor funerare cu datele genetice antice (ADNa)
informații despre dietă obținute prin analiza faunei și a izotopilor stabili din oasele umane și animale
dar și proveniența mineralogică și geochimică a materialelor litice
O scurtă trecere în revistă a progreselor recente în studiile asupra Neoliticului timpuriu din nord-vestul Bulgariei și din regiunile învecinate va pune în perspectivă importanța acestor descoperiri
Petar Zidarov este cercetător asociat la Universitatea din Tübingen și arheolog independent
În ultimii patru ani a lucrat în colaborare cu Institutul Național de Arheologie și Muzeu din Sofia
Muzeul Regional de Arheologie din Plovdiv și
cu Centrul de Arheologie Subacvatică din Sozopol
a lucrat timp de 12 ani (2008–2020) în cadrul Laboratorului de Arheometrie și Arheologie Experimentală de la Universitatea Nouă din Bulgaria
unde a susținut o teză de masterat dedicată sitului chalcolitic de la Durankulak
iar studiile doctorale – aflate în curs de finalizare – s-au concentrat asupra industriei osoase din Epoca Bronzului de la Troia
Activitatea sa de cercetare include analize ale uneltelor și podoabelor din os din perioada neolitică și chalcolitică
desfășurate în cadrul unor colaborări internaționale
precum cele de la Pietrele (cu Svend Hansen)
Teleac (alături de Nick Boroffka și Horia Ciugudean) și
Bucova Pusta (cu Raiko Krauss și Dan Ciobotaru)
La Pietrele și Bucova Pusta s-a ocupat de studiul materialului osteologic prelucrat
iar la Pietrele și Teleac a realizat prospecțiuni geomagnetice
Zidarov a studiat materiale provenite de la numeroase situri preistorice de referință precum Troia
A efectuat prospecțiuni magnetometrice pe peste 120 de situri din Bulgaria
proiectele desfășurate în zona siturilor pre-neolitice de la Göbekli Tepe
Evenimentul este organizat de Universitatea din București sub umbrela proiectului „Centru regional de Orientare și Consiliere în Cariera de Cercetător – București-Ilfov – de la educație preuniversitară la cercetare avansată” (SciResCareer)”
finanțat în cadrul PNRR/C9/ Investiția „I10 – Înființarea și susținerea financiară a unei rețele naționale de opt centre regionale de orientare în carieră ca parte a ERA TALENT PLATFORM”
Aceste seminare sunt o inițiativă originală a Platformei ArchaeoSciences (ASp) din cadrul ICUB
care își propune să ofere un cadru de exprimare profesioniștilor din domeniul științelor arheologice din diferite părți ale lumii pentru a împărtăși cunoștințe și a transmite informații semnificative despre cele mai recente probleme referitoare la metodele și abordările actuale utilizate pentru studierea trecutului
reprezintă o șansă pentru studenții români de a afla mai multe despre diversele aspecte interdisciplinare ale arheologiei
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Courtesy of White Arkitekter ABThe combination of wood as an essential structural material on the upper floors and renewable raw material in the expansion and façade enable savings in greenhouse gas emissions
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Infectious Diseases: Epidemiology and Prevention
Volume 11 - 2023 | https://doi.org/10.3389/fpubh.2023.1159622
population mobility remains the main reason for the spread of SARS-CoV-2
The state of Baden-Württemberg (BW)
approved a model study in Tübingen (TÜMOD) to evaluate how mandatory rapid diagnostic tests (RDT) could reduce transmission
approximately 165,000 residents and visitors to the city were screened for SARS CoV-2 infection using Abbott Panbio™ COVID-19 Antigen rapid test device
We assessed incidences and recorded epidemiological characteristics in a subset of 4,118 participants recruited at three of the nine testing stations
PCR tests were performed in RDT-positives to determine the positive predictive value (PPV)
and circulating variants of SARS-CoV-2 were identified by whole-genome sequencing
2,282 RDT-negative samples were tested by pooled PCR to calculate the false negative rate (FNR)
116 (3%) participants were positive by RDT
52 SARS-CoV-2 genomes were successfully sequenced
which had a high viral load (average Ct = 19)
had reached the incidence in the state of BW
While it is difficult to assess the impact of TÜMOD on incidence independent of confounding factors
further studies are needed to identify the effect of close-meshed testing on infection rates
Population mobility remains the main reason for the spread of SARS-CoV-2, and various forms of contact restrictions, including lockdowns, have been enacted in response to the COVID-19 pandemic, resulting in enormous economic burdens at both the individual and societal levels (1, 2)
One way to limit this burden is to introduce a large-scale rapid SARS-CoV-2 test as a complementary measure to overcome the lockdown and enable a safe resumption of public life while containing the risk of an increase in infections
In Germany, several infection control measures were taken in early 2021, such as restricting retail, catering and cultural events, and limiting the size of public gatherings, while RDTs have been available since late 2020 (6). In this context, the state of Baden-Württemberg (BW) approved the implementation of a model study in the city of Tübingen (Tübingen Model Study, TÜMOD) (7)
Its main objective was to assess how mandatory RDT testing could enable the reopening of public facilities without risking an increase in infections
In addition to continuous monitoring of incidence
the study had three main objectives: (a) to conduct an epidemiological survey among individuals with positive and negative RDT results for SARS-CoV-2
(b) to compare SARS-CoV-2 RT-qPCR with RDT results and determine the positive predictive value (PPV) and false negative rate (FNR)
(c) to conduct SARS-CoV-2 genome sequencing to determine viral lineages in circulation
During the TÜMOD study from 16 March to 24 April 2021 (7)
and cultural facilities could only be visited by clients holding a negative RDT certificate no more than 24 h old
nine testing stations throughout the city offered free RDT testing every day
individuals were reported to the health authorities and subsequently referred for PCR testing
positive RDTs were not included in the 7-day incidence per 100,000 inhabitants
which is calculated from positive SARS-CoV-2 RT-qPCR only
participants undergoing RDT testing were included from 22 March to 19 May 2021 (Cohort1)
cohort 2 was recruited at RDT testing sites for university staff members from 26 April to 22 June 2021
RDT: Rapid Diagnostic Test; PCR: Polymerase Chain Reaction; ITM: Institute for Tropical Medicine
University of Tübingen; Ct: cycle threshold
If PCR was performed at the local reference laboratory in Tübingen
the same swab material was used for RT-qPCR for independent confirmation at the ITM (n = 65)
if PCR was analyzed at another laboratory outside of Tübingen
participants were asked to provide a second oropharyngeal swab at the testing site on the same day for analysis at the ITM (n = 47)
Four RDT-positive individuals could not be confirmed by PCR at the ITM because no sample could be obtained
Participants with a positive RDT result were recruited from 22 March to 19 May 2021
Although the model study ended on 24 April
the testing facilities in Tübingen remained accessible to the Tübingen population and recruitment of RDT-positive participants continued until 19 May 2021
As a high rate of false positive RDTs became apparent
it was decided to also investigate the false negative rate (FNR)
Pooled PCR testing was performed in 2,282 RDT-negative individuals to determine the FNR
Since the model study had already ended and the demand at the test stations in the city had diminished
participants were recruited between April 26 and June 22
2021 at five testing stations set up for University of Tübingen staff
and PCR testing was performed in pooled samples at CeGaT
RT-qPCR was performed within a median of two days (range: 0–11 days) after sample collection
The 7-day incidence per 100,000 inhabitants as well as the number of new infections with SARS-CoV-2 was obtained from the website of the Robert Koch Institute, the central federal authority for disease surveillance and prevention in Germany (16, 17). The population of BW and its districts in the second quarter of 2021 was retrieved from the State Statistical Office of BW (18)
These included the BW cities of Heidelberg (weight 0.431 in the synthetic control model) and Freiburg im Breisgau (weight 0.300) and the districts of Enzkreis (weight 0.254) and Heilbronn (weight 0.016)
It was expected that incidence in Tübingen district would increase during TÜMOD because of increased testing
leading to the detection of more infections but not necessarily reflecting more infections in the district
the number of true positive RDTs was estimated from the number of total positive RDTs based on a PPV of 0.5 for each week
these true positive tests were subtracted from the number of new infections per 100,000 population in a week as they were possibly detected only because of the increased testing during the TÜMOD
The proportion of different SARS-CoV-2 lineages was compared by residence of infected individuals
and viral load by Ct values was compared between lineages in the Student’s t-test
The epidemiological characteristics of the study participants are shown in Table 1
the regulations as to who was allowed to participate in activities of the model study changed on 1 April 2021
the place of residence can only be compared between uninfected and infected individuals until then
there was no major difference in the places of residence between the groups
one around the mid-twenties and one around the 60s in both groups
Three of the 46 infected individuals were children (aged 7 to 16 years) belonging to two families
the proportion of males among those infected was higher (p = 0.01)
The infected more often lived with children in their household (p = 0.02) and had more children than the uninfected (p = 0.008)
They also were less likely to work in home office (p = 0.0002)
The proportion of people who had received at least one dose of SARS-CoV-2 vaccine was higher among the uninfected
although the difference was not significant (18% versus 9%
There were no differences in the proportion of people with a positive test on a previous occasion between infected and uninfected people (p = 0.71).Remarkably
those infected were much more likely than those not infected to give other reasons for testing (none of the reasons “shopping,” “tourism,” “going to restaurants or private meetings” applied) (46% vs
False and true RDT-positives were also compared (Table 2)
False positives did not differ from the true positives in age (p = 0.15)
The two groups did not differ in sex distribution (64% vs
The reason “Other” was also much more prevalent among true positives (46% vs
while “Shopping” was given less frequently (15% vs
The number of participants who had received at least one dose of a vaccine against SARS-CoV-2 was high among false positives but was not significant (26% vs
To assess the performance of the Abbott Panbio™ COVID-19 Ag rapid test under real-life conditions, swabs from participants with positive RDT were analysed by RT-qPCR. A PPV of 51% (57/112, 95% CI 41–60%) was observed (Supplementary Table). Among vaccinated individuals, the PPV was even lower at 24% (4/17, 95% CI 7–50%). As shown in Figure 1
a subset of 65 samples were subjected to RT-qPCR at CeGaT before sending the remaining swab materials to the ITM for confirmatory RT-qPCR and sequencing
which was negative for SARS-CoV-2 infection at CeGaT
all remaining 64 samples had concordant results in the RT-qPCR at both laboratories
One RDT positive sample had a Ct > 34 at both laboratories
which was considered a negative result for this analysis
A second cohort for the FNR determination was recruited at testing stations for members of the University of Tübingen only
A total of 2,282 individuals with a negative RDT result participated and were tested by RT-qPCR for SARS-CoV-2 in 135 Pools
None of the pools yielded a positive result
therefore the FNR in this cohort was zero (95% CI 0–0.0016)
the incidence at the pool-testing sites was very low throughout the period
as none of the over 11,000 RDTs conducted there was positive
0.15% of all RDTs performed at the testing sites in the city were positive
Assuming a similar prevalence at the pool-test stations
about 15 positive RDTs would have been expected there in total
the prevalence at these sites must have been lower than at the testing stations in the city of Tübingen
It is therefore not possible to combine the two datasets to calculate sensitivity and specificity of the RDT
the increase in infections was steeper in Tübingen than in the whole state of BW
leading to an assimilation of 7-day incidence in Tübingen to that of the state during the model study
TÜMOD = Tübingen model study
TU = district of Tübingen
FR = city of Freiburg im Breisgau
BW = Baden-Württemberg
The difference between these two groups was significant (p < 0.01)
the phylogenetic tree likely did not contain sufficient temporal information to conduct a meaningful analysis on phylodynamics during TÜMOD
the infected persons often made use of the testing opportunities because they already had a reason to believe that they were infected
This might explain the fact that they more often stated “other reasons for testing.” Informal communication between subjects and examiners revealed that they often had contact with an infected person or had symptoms of SARS-CoV-2 infection
Since persons already suspected of being infected should be separated from tourists and shoppers at the testing sites to reduce the risk of transmission while waiting for the test
it is important to set up separate testing sites for them
This was done at the referral PCR testing centre
but apparently not communicated clearly enough to the community
This is consistent with our finding that participants who reported a reason for testing other than shopping
visiting restaurants or private gatherings had more true positives
which may indicate a higher prevalence in this subgroup
the prevalence of SARS-CoV-2 might have been very low in this cohort
represented exclusively by university staff - a selected group that might have been more privileged in terms of exposure to the virus than the average visitor to the Tübingen model project
The vaccination rate could also be higher in this subgroup
The alpha variant of concern (line B.1.1.7) was identified in most SARS-CoV-2 isolates from TÜMOD participants. Higher viral loads (27) and infectivity (28) were observed in infections with this variant
which replaced the B.1 lineage in Europe in early 2021
The number of SARS-CoV-2 infections in the districts of Tübingen increased fivefold during the study period and reached an equilibrium as in the federal state of BW in April
As this trend was observed in most areas of Germany between March and April 2021
it is difficult to draw conclusions about a causal relationship with the model project
The incidences of SARS-CoV-2 infection in the district of Tübingen was analysed and compared to a synthetic control model by Diederichs and colleagues (20)
By creating a “virtual twin” of the Tübingen district
they aimed to determine the effect which TÜMOD had on the incidences
The authors compared the 7-day incidence per 100,000 inhabitants between Tübingen and their synthetic control and calculated the incidence in Tübingen without cases detected only due to the model study
They found that there were fewer cases in Tübingen at the beginning of the model study than would have been expected without the study
but that the case numbers rose in early April more than can be explained by increased testing alone
it can be argued that TÜMOD was responsible for a modest increase in documented infections in early April
Limitations included the fact that only a fraction of RDT positives could be interviewed
so that their group was significantly smaller than that of RDT negatives
the negative ones were only interviewed during a short period at the beginning of the study
the first cohort for PPV determination and epidemiological analysis and the second cohort for FNR analysis
were not recruited from the same parent population due to organizational restrains
they cannot easily be compared to each other and sensitivity and specificity of the RDT cannot be calculated
no epidemiological data at the level of the city of Tübingen were available for a detailed evaluation of the infection incidence
The Tübingen model project intended to assess the effects of cautious revival of social and economic life under close-meshed testing
incidence increased to the level of the state of BW
to draw firm conclusions about the impact of TÜMOD on district incidence due to several possible confounders and the natural lack of a “control group,” which would have to consist of a second
the model trial allowed the city to return to a freer public life to some extent
The implementation of broad-based testing strategies in low-prevalence settings also resulted in a low PPV
which must be accounted for in the assessment of the endemic situation
informing the population about the intended use of the test offers is crucial to direct people with suspected infection to separate test centres
Epidemiological surveys suggested an increased risk of infection for males and people living with children in their household
and a protective role of working in home office
The dominating lineage was B.1.1.7 during the whole model project
The vaccination rate has now reached 75% or more
but new variants such as Omicron and its sub lineages are dominating the community
These new factors could have a major impact on the sensitivity and PPV of RDTs and must equally be given consideration in future testing strategies
this is an interesting study model that the city of Tübingen has carried out with the perspective of keeping business and social life alive in the city while accounting for the risk of an increase in infections
The datasets presented in this study can be found in online repositories. The names of the repository/repositories and accession number(s) can be found in the article/Supplementary material
The studies involving humans were approved by Ethics Commission of the Medical Faculty of the Eberhard-Karls University and the University Hospital of Tübingen
The studies were conducted in accordance with the local legislation and institutional requirements
Written informed consent for participation in this study was provided by the participants' legal guardians/next of kin
and writing – review & editing
FB: investigation and writing – review & editing
All authors contributed to the article and approved the submitted version
The authors acknowledge the support of the township Tübingen and Land Baden Württemberg in sponsoring this study
FB is employed by Center for Genomics and Transcriptomics (CeGaT) GmbH
The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations
Any product that may be evaluated in this article
or claim that may be made by its manufacturer
is not guaranteed or endorsed by the publisher
The Supplementary material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fpubh.2023.1159622/full#supplementary-material
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Real-life validation of the Panbio™ COVID-19 antigen rapid test (Abbott) in community-dwelling subjects with symptoms of potential SARS-CoV-2 infection
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Comparing susceptibility and contagiousness in concurrent outbreaks with a non-VOC and the VOC SARS-CoV-2 variant B.1.1.7 in daycare centers in Hamburg
Kremsner PG and Velavan TP (2023) Tübingen model study: large-scale introduction of rapid antigen testing in the population and the viral dynamics of SARS-CoV-2
Received: 06 February 2023; Accepted: 06 October 2023; Published: 24 October 2023
Copyright © 2023 Ayran, Köhler, Linh, Schneider, Pallerla, Battke, Federle, Martus, Kremsner and Velavan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY)
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*Correspondence: Thirumalaisamy P. Velavan, dC52ZWxhdmFuQHVuaS10dWViaW5nZW4uZGU=; Peter G. Kremsner, cGV0ZXIua3JlbXNuZXJAdW5pLXR1ZWJpbmdlbi5kZQ==
†These authors share senior authorship
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The Universities of Nottingham and Tübingen have announced their intention to expand their cross-border partnership to cooperate more closely on cutting-edge research to solve some of the world’s greatest challenges
A delegation from Nottingham led by Vice-Chancellor Professor Shearer West has been in Germany this week for the signing of a strategic partnership agreement with the University of Tübingen
which builds on several years of mutual investment into research
The signing ceremony was led by Professor West and Tübingen’s recently appointed Rector Professor Karla Pollmann
and was attended by senior leaders from both institutions
Professor West announced a significant investment by Nottingham into the partnership
She added: "The great complementarity in our respective institutional and research expertise will lead to even greater outcomes
That is why I am also pleased to announce today that the University of Nottingham is investing a further £320,000 into this relationship.”
This investment includes a seed fund of £125k which will be matched by Tübingen to further engage in research collaboration between both institutions
The investment in this partnership does not begin here
In May 2020 the first investment initiative of this partnership was undertaken in the form of a joint research workshop
The workshop challenged academics to explore how they might work collaboratively
bringing their respective and complementary areas of research together to create real-world impact
This ultimately led to identifying several priority themes based on existing connections:
The two universities agreed to a joint funding round of seed funding and co-supervised studentships
with Tübingen generously matching Nottingham’s £30k with a €70k investment
Professor West added: “Since investment in the partnership through dedicated resource
our joint researcher outputs have increased by 220 per cent from 2019 to 2021
something that will only continue to grow as a result of our joint seed fund investment in new and innovative projects.”
Though new to her position at the University of Tübingen
Professor Karla Pollmann is equally committed to the success of this strategic partnership and said: “British universities are currently
an indispensable pillar of European research
it is of great importance for the University of Tübingen to maintain and strengthen our traditionally excellent relations with British academic institutions
This will not only benefit students and researchers at Nottingham and at Tübingen
but also society and economy in Germany and the UK as a whole.”
The partnership will open their second seed fund call early this year and both institutions look forward to supporting the development of this partnership in the years ahead
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By Amy L. Allocco
December 14, 2020
“Living with the Dead in Hindu South India,” draws on Allocco’s current ethnographic research project and was sponsored by the Asia-Orient Institute
associate professor of religious studies and director of the Multifaith Scholars Program
recently delivered an invited lecture titled “Living with the Dead in Hindu South India” via Zoom at the University of Tübingen in Germany
Sponsored by the Department of Ethnology within the Asia-Orient Institute
her lecture drew on her long-standing ethnographic research on ritual relationships with the dead in Hindu South India
Allocco offered an overview of her current research project
which analyzes the abiding relationships that many communities maintain with their deceased kin in Tamil-speaking South India
before focusing her presentation on a class of dead called puvataikkari
who are worshiped as family deities and may be ritually invited back home to reside as a permanent household protector
which was published in The Journal of Hindu Studies earlier this year
relies on more than a decade of fieldwork and interviews with one Hindu family in South India to explore the hermeneutical issues – what Allocco calls “interpretive ambivalence” – that arise from narrative multiplicity
Audience members engaged Allocco in an hour of robust discussion and question-and-answer following her presentation
Ambos is one of eight scholars who will be presenting a paper in a double panel that Allocco is convening for The Annual Conference on South Asia in Madison
Focused on the theme of “Intensification vs
New Patterns in Contemporary Hindu Representation and Practice,” the two panels were to have been delivered at the Conference on South Asia this past October
but the meeting was postponed to 2021 due to COVID-19
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Elon University Professor of History Michael Matthews explores the romantic and sexual lives of Mexico City’s poor and working class during the rule of Porfirio Diaz
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