Facility in Høje-Taastrup will heat 6,000 dwellings Waste heat from a new Microsoft data center in Denmark will warm up to 6,000 homes The data center in Høje-Taastrup, 25km west of Copenhagen, is one of three being built to provide a Danish Azure availability zone announced in 2020 Warm water from the site's cooling system will be repurposed by VEKS which builds district heating systems around Copenhagen The three are intended to provide a reliable service that meets the requirements to store Danish citizens' data locally in Denmark VEKS and Microsoft expect the first deliveries will be ready to reach residents during the 2025–2026 heating season Microsoft has been posting construction updates for the site since 2022 The data center was announced and approved in 2022 and included plans to recycle heat from the start "In Høje-Taastrup Municipality, there has been a desire from the start to utilize the excess heat from the data center," he told Zealand News in 2022 the surrounding infrastructure makes this possible and we have had good cooperation with Høje Taastrup Fjernvarme (HTF)." The data center provides lukewarm water at 20-30oC which is cheaper for HTF to heat up using heat pumps “There’s considerable potential for surplus heat from data centers in the Greater Copenhagen area," said Steen Christiansen Other data centers in the area include one being built by DigiPlex (now Stack) which has also committed to give its warm water to the local community Microsoft has also promised to keep a green area adjacent to the data center which is one of 17 green areas to be developed in the municipality Data Centre Dynamics Ltd (DCD), 32-38 Saffron Hill, London, EC1N 8FH Email. [email protected]DCD is a subsidiary of InfraXmedia The Local Europe ABVästmannagatan 43113 25 StockholmSweden Staff at PostNord's Taastrup terminal resumed work on Thursday afternoon The company confirmed the strike in a statement earlier on Thursday saying it could result in delayed deliveries in the coming days Following the resumption of work by sorting staff Letter deliveries could be delayed by a single day “I can confirm that a strike began yesterday in breach of the collective bargaining agreement at our post terminal at Taastrup,” PostNord director of communications Andreas Brethvad said in Thursday's statement READ ALSO: EXPLAINED: What is a Danish collective bargaining agreement? “The strike in question is among staff who handle letters,” he said The company was unable to comment on the reason for staff taking the action saying that was a matter for their trade union Any delays to deliveries may be relevant news for British residents in Denmark who plan to vote by post in the upcoming UK General Election READ ALSO: The key deadlines Brits in Europe need to know to vote in the UK election you will be sent a ballot paper which will need to reach the polls by polling day where a UK-based voter you trust can vote on your behalf You can also travel back to the UK on election day and vote in person in the constituemncy where you're registered but unless you just happened to be planning a visit home at that time anyway it's probably more convenient to apply for one of the two above options If you apply for a proxy vote online you've got a bit more time but you'll need to submit your application for this by 5pm on June 26th Please log in here to leave a comment The order was received from Høje Taastrup Fjernvarme and VEKS who are currently constructing the 70,000 m3 PTES solution in Høje Taastrup Aalborg CSP will deliver an advanced lid solution tailor-made for large-scale This PTES project is an example of flexible and efficient sector coupling of electricity and district heating Sector coupling through energy storage is one of the main elements within the sustainable energy system of the future and thus a key element in reaching the global environmental energy and climate targets of the next decades Høje Taastrup Fjernvarme and VEKS are currently establishing a 70,000 m3 PTES Integrated Energy Solution in Høje Taastrup near Copenhagen Denmark – a project which will include the world’s most advanced PTES lid technology developed and patented for large-scale commercialization The parties have recently signed a contract with the Danish renewable and energy storage specialist for design and delivery of a 11,000 m2 insulating lid The purpose of the PTES lid is to minimise the heat loss inside the PTES The lid solution from Aalborg CSP is based on the development of a durable technology which ensures stable operation over the lifetime of the project The PTES in Høje Taastrup is a thermal storage functioning as a thermal battery with a capacity of 3,300 MWh The thermal battery is charged by heat from the transmission grid and discharged to the district heating network when the demand for heating increases when the price on heating is low and is utilized later on The PTES project in Høje Taastrup is a great example of flexible and efficient sector coupling within the power and district heating sectors Sector coupling is one of the main elements within the sustainable energy system of the future and is thus a key element in reaching the global environmental “It is the first time this type of storage is used in one of the very large district heating networks in Denmark” said Astrid Birnbaum To further optimise the durability and lifetime expectancy of the storage we have worked with different types of technical solutions We chose the new PTES lid solution from Aalborg CSP as we believe that it is a reliable solution added that the lid solution is ‘state of the art’ which the entire district heating supply and thus all district heating customers within the metropolitan area of Copenhagen will benefit from The aim of the PTES Integrated Energy System project in Høje Taastrup is to make the district heating supply more efficient and minimize the expensive peak load production Besides reducing the peak loads that occur throughout the day within a district heating network the storage will also add flexibility to the heat production for optimal utilization of the district heating Høje Taastrup and VEKS will benefit from a PTES solution with a lid that prevents accumulation of air water and moisture inside the insulation in an efficient way The PTES lid helps increase the efficiency and reliability of the storage and ensures long-term durability of the storage The purpose of the new design is to address and solve the problems and challenges as well as minimising the risks which are typically experienced during the installation and operation of a PTES This design improves the quality and reliability of PTES systems contributes to lower heating bills for the consumers and adds flexibility to the energy system The PTES lid solution from Aalborg CSP differs from traditional PTES lids in a number of ways a long lifetime and reduces the heat loss inside the storage These unique design features minimise the heat loss inside the PTES and is contributing to increased efficiency and reliability of the complete energy system This is a key step in commercialising the PTES technology where it is expected to see millions of m3 capacity of PTES Integrated Energy Solutions installed in Denmark as well as other European countries A full-scale version of the new PTES lid design has been tested at Marstal Fjernvarme where it has been included in the Integrated Energy System already counting Solar and Biomass the new lid replaced the original PTES lid which was of a previous design and damaged due to moisture accumulation inside the PTES lid construction This recent replacement has resulted in a full-automatic operation with a minimum of maintenance and supervision the heat loss inside the PTES has been reduced Aalborg CSP Reflecting on the unexpected success of the weekend Walsh admitted that she will now have to reset her goals for the rest of the long course season Carlson has the potential to impact UIC in the 200 free where last season’s top times were held by graduate students Spain repeated as the Men’s Water Polo World Cup champions and secured a spot to compete in Singapore April 19th, 2021 Europe, International, News, Previews & Recaps The Danish Open got underway over the weekend with Olympic medalist Jeanette Ottesen in the pool racing her bread-and-butter sprint fly events the 33-year-old mother produced a solid swim of 25.98 in the women’s 50m fly a time which garnered her the silver medal behind teammate Emilie Beckmann just .12 outside her lifetime best in the event The pair are also seeded 1-2 after this morning’s 100m fly heats with Beckmann snagging lane 4 in 58.49 to Ottesen’s 58.90 The former owns a PB of 58.01 in this event while the latter owns a career-quickest of 56.51 from back in 2014 Ottesen punched a 1fly result of 58.75 at a FINA Champions Series meet The men’s 100m fly saw Danish junior record holder Rasmus Nickelsen surge to the wall first in 53.04 to give the Helsingør Swimming Club the pole position entering tonight’s final Δdocument.getElementById( "ak_js_1" ).setAttribute( "value" Δdocument.getElementById( "ak_js_2" ).setAttribute( "value" Had to laugh at chrome’s translation to English of the results I can only assume that “aircraft” is the English translation of butterfly whereas breaststroke is translated to chest for men and breast for women Former Masters swimmer and coach Loretta (Retta) thrives on a non-stop but productive schedule that includes having earned her MBA while working full-time in IT while owning French 75 Boutique while also providing swimming insight for BBC More from Retta RaceSee All Subscribe to our newsletter and receive our latest updates your new go-to podcast to spice up your weekday mornings with relevant news and behind-the-scenes from Brussels and beyond From the economy to the climate and the EU's role in world affairs this talk show sheds light on European affairs and the issues that impact on our daily lives as Europeans Tune in to understand the ins and outs of European politics Dare to imagine the future with business and tech visionaries Deep dive conversations with business leaders Euronews Tech Talks goes beyond discussions to explore the impact of new technologies on our lives the podcast provides valuable insights into the intersection of technology and society Europe's water is under increasing pressure floods are taking their toll on our drinking water Join us on a journey around Europe to see why protecting ecosystems matters and to discover some of the best water solutions an animated explainer series and live debate - find out why Water Matters We give you the latest climate facts from the world’s leading source analyse the trends and explain how our planet is changing We meet the experts on the front line of climate change who explore new strategies to mitigate and adapt Remember the struggle of staying awake in those early morning classes at school it was hard to fall asleep at night and he often went to school without having had enough sleep "You lie and turn and turn for a long time and cannot fall asleep," he told Euronews Health Public health and sleep experts in Denmark say young adolescents have a different circadian rhythm than adults and that teenagers in the Nordic country don't get enough sleep According to a report from the National Institute of Public Health teenagers should sleep eight to 10 hours a day but almost 60 per cent of 15-year-olds today sleep less than that The report contends that this is due to both bodily changes and the use of screens in the evening a hormone that the human body releases at night to induce sleep a stress hormone that wakes up our body respectively are released later in the day in teenagers than in adults "If you ask a teenage daughter at 10 pm to go to bed and she says 'I'm not sleepy yet,' then she [may] not be lying So the physiological needs of teenagers do not fit with how the school system is structured demanding them to go to school early," Cathrine Wimmelmann a senior researcher at the Centre for Childhood Health The consequence of too little sleep can lead to an increased risk of unhappiness and the development of stress and depression Amid a growing awareness of youth mental health several schools in Denmark have trialled changing their start times since the summer of 2023 began letting pupils aged 13 to 16 (between Danish 7th and 9th grades) start at 9 am instead of 8.10 am "You get better quality sleep and you fall asleep faster," Rasmus said we were very tired and quite upset in the morning There were a lot of us feeling drowsy and we didn't really care for each other," Emily We talk to each other instead of looking down at our phones," she added they sleep longer and they actually have more energy Not only in the morning but also during the day and when they have to do their activities outside of school," Tine Agerholm Kristiansen Langs Skole collaborated with a Danish tech start-up to track the sleep of students between the 7th and 9th grades via an app the school found that students slept an average of 7 hours and 58 minutes during the tracking period and showed improvement in sleep duration and fatigue during the first three months of the initiative how much time they spend in bed actually sleeping it had risen a lot," Karina Juul Uldal Christesen "Our then-seventh-grade class used to spend an average of 3.5 hours falling asleep before the project Our ninth-grade class dropped to about half an hour," Christesen added Langs Skole has spread throughout the country and inspired other schools over the past two years there are about 20 schools in Denmark that have pushed back their start times was one of the latest ones to follow suit when the current school year started we have started with the senior students [who] are meeting one hour and 15 minutes later than all the other students because of their sleeping habits," said Kennet Hallgren Students here have had similar positive experiences "I'm very satisfied because I go to bed at the same time So I get basically one hour more sleep so I can be more productive in school and I'm more focused," said Julius a 13-year-old (7th-grade) student at Taastrup Realskole and I'm now more concentrated in school and I can learn more," said Lina Experts say a later start time shouldn’t mean a later finish time to ensure students have enough free time after school The easiest way is to just prolong the day; Meeting later because that would compromise the students and spare time activities," Wimmelmann said "We need to think creatively in terms of how to structure the school day,” she added nothing prevents schools beginning later so long as the target hours are met "There is only an actual legal requirement that the teaching must take place between approximately 8 am and 4 pm unless there are special events," according to Denmark’s Ministry of Education "It is up to the schools and the municipalities to decide how the teaching is to be organised and the municipalities decide how many and how long school days pupils should have choose to operate with more school days than usual whereby the days can each be slightly shorter" Langs Skole and Taastrup Realskole have more regulatory freedom and resources to restructure their curricula to implement a later school time but… we have put two teachers in some of the lessons," Anja Nordgaard Roland Some public schools have also managed to start later and end at similar times as before by adjusting school curricula While experts believe it’s a promising initiative given the physiology of teenagers they warn there are a few caveats many of the schools that have implemented the initiative have not had methodologically scientific evaluations of the initiatives," Wimmelmann said "Many of the studies that evaluate these initiatives only address sleep duration and that is only half of the story," Wimmelmann added "We mostly look at sleep duration and not the quality of sleep [in these studies] and they're both really important for the outcomes; cognitive ability and Singapore have tried similar experiments and yielded positive results Wimmelmann says it’s unclear whether the effects will last for a longer period "The very positive results from some of these studies are a few years old I think they cannot necessarily be transferred and used today because a lot happened to young people's lives," Wimmelmann added Experts say moving a school's starting time alone is not sufficient and addressing other health behaviours such as the screen or physical activity could help improve or support the effects of the initiative with later school start times "Screen use definitely affects sleep quality; the waves We wake up more if we have been looking at a screen until we fall asleep," said Wimmelmann The schools that have pushed their start times admit that mitigating students’ screen time is a challenge but important to ensure better sleep and improve the well-being of their pupils is a public school that has delayed its starting time and run a campaign named 'Healthy Sleep and Healthy Screen' According to its recently published evaluation report the school actively communicated "key tips" for healthy screen use with its pupils as well as tracked their sleep and screen time using technologies and sleep duration and efficiency increased in all 7th classes that participated in app courses and tracking for four weeks Wimmelmann says the number of teenagers who don't sleep enough has doubled since the 1980s "We have known and discussed this for years focus on mental well-being among our youth," said Wimmelmann "We are talking about a mental health crisis at the moment Society and the research environments are all very preoccupied with finding solutions to how we can improve the living conditions for our young people obvious way to adjust the system to their needs," she added Just Human is a Danish NGO that works "to inspire schools and lawmakers to consider implementing later school start times" It launched the project ‘Later Meeting Time’ five years ago when most schools were reluctant to embrace the idea "Structural changes are needed to improve the well-being of children and young people and to turn around this mental-health crisis," Eva Molin the ‘Later Meeting Time’ project manager at Just Human "By letting the teenagers start school later in the morning we can give them the opportunity to sleep more and this can have a great positive effect on their well-being learning potential and social interactions There are so many great benefits," she added "We are very happy to see now that the schools are opening up for this idea and that they realise the benefits that the later start times could give the students" About seven municipalities in Denmark are currently engaged in active discussions about support for schools to try a later start time "They're opening up and trying to investigate – 'how can we do it in our municipality?,' 'What can we do this to support young people's sleep and therefore overall mental health and well-being?'" said Molin To investigate the in vitro effects of clinically relevant concentrations of the local anesthetics (LAs) bupivacaine and ropivacaine on equine chondrocyte and fibroblast-like synoviocyte (FLS) viability Chondrocytes and FLSs of the metacarpophalangeal joints of 4 healthy adult horses Viability of chondrocytes and FLSs was determined with 3 assays: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) Viability was assessed after 30- and 60-minute exposures to 0.0625% Viability of chondrocytes was significantly decreased with exposure to 0.25% bupivacaine Viability of FLSs was significantly decreased with exposure to 0.25% bupivacaine Clinically relevant concentrations of LAs had in vitro time- and concentration-dependent cytotoxicity for chondrocytes and FLSs isolated from the metacarpophalangeal joints of healthy horses Bupivacaine was more toxic to chondrocytes than lidocaine and ropivacaine were more toxic to FLSs than preservative-free lidocaine Several LAs may negatively affect chondrocyte and FLS viability synoviocyte death may reflect an indirect pathway of cartilage injury The objective of the study reported here was to further investigate the in vitro effect of 3 clinically relevant concentrations of 5 LAs (bupivacaine and ropivacaine) currently available in equine practice on the viability of isolated equine chondrocytes and synoviocytes Cartilage and synovial membrane were collected postmortem from both metacarpophalangeal joints of 4 horses aged 5 to 12 years and without clinical signs of orthopedic disease Horses were evaluated subjectively for lameness on a straight line on a hard surface prior to euthanasia and were excluded from the study if they were lame or had synovial effusion of either metacarpophalangeal joint The articular surface and synovial membrane were inspected postmortem for macroscopic evidence of cartilage degradation Horses were euthanized for reasons unrelated to the present study by captive bolt followed by exsanguination according to Danish law and regulations The Ethical and Administrative Committee at the Department of Veterinary Clinical Sciences University of Copenhagen approved the study protocol (protocol No and horses were included after informed consent by their owners Chondrocytes and FLSs were isolated as previously described.18 Articular cartilage was harvested aseptically from the distal aspect of the third metacarpal bone Chondrocytes were isolated at 37°C by sequential digestion in high-glucose DMEM (4.5 g/L) that contained penicillin (300 U/mL) and gentamicin (50 µg/mL) with added 0.1% pronase for 1 hour followed by an 18-hour incubation with added 0.15% collagenase type II Released chondrocytes were rinsed and cultured in a monolayer in 96-well culture plates at a density of 40,000 cells/well in an incubator at a controlled humidified atmosphere (37°C; 5% CO2) in high-glucose DMEM with 10% fetal calf serum Synovial membrane was harvested aseptically from the metacarpophalangeal joint cavity Fibroblast-like synoviocytes were isolated at 37°C by digestion in high-glucose DMEM (4.5 g/L) that contained penicillin (300 U/mL) and gentamicin (50 µg/mL) with added 0.15% collagenase type I for 3 hours Released FLSs were rinsed and cultured in a monolayer in T75 flasks in an incubator with a controlled humidified atmosphere (37°C; 5% CO2) in high-glucose DMEM with 10% fetal calf serum and gentamicin (50 µg/mL) until 80% cell confluence when cells were then passaged 3 times by use of 0.05% Trypsin-EDTA cells were seeded in 96-well culture plates at a density of 40,000 cells/well (day 0) On day 2 of the cultures of chondrocytes and FLSs culture media were modified to exclude serum and phenol red (ie serum- and phenol red-free [conditioned] media) Cells not incubated with an LA (control) were instead incubated with 100 µL of saline solution plus 100 µL of culture media All assays were performed according to manufacturers' protocols Incubation time was recorded for each plate the total number of cells and the number of cells with absorbed blue dye (nonviable cells) were counted Calculations and statistical analyses of cell viability associated with each LA were based on the ODs of treated and control wells for the MTT and LDH assays whereas cell viability was based on a count of the number of nonviable cells for the TB assay Cytotoxic effect of each LA was calculated for the specific assays according to their manufacturers' instructions as follows: MTT assay: ([control OD – sample OD]/control OD) × 100 LDH assay: ([sample OD – control OD]/[positive control OD – control OD]) × 100 percentage cell viability was determined by subtracting the calculated percentage for each LA and assay from 100% control wells were calibrated to 100% viability and treated wells were reported as a percentage of the calibrated control wells for each assay Cell viability > 100% indicated a higher viability for the treated cells than the control cells Statistical analyses were performed with commercially available software.k Normality was assessed with the Shapiro-Wilk test The 60-minute chondrocyte data set for the LDH assay was logarithmically transformed to normalize its distribution Cell viability was compared between control and LA-treated cells with a 1-way ANOVA for repeated measures on normally distributed and log-transformed data and then results analyzed post hoc with the Tukey test Data for the MTT and TB assays for FLSs after 60 minutes of LA exposure were not normally distributed and were analyzed with the Friedman test and then analyzed post hoc with the Dunn test Values of P < 0.05 were considered significant After 30 minutes of exposure to 0.0625%, 0.125%, or 0.25% bupivacaine, cell viability did not significantly differ, compared with control, but viability was significantly (P = 0.037) lower for cells exposed to 0.25% bupivacaine versus those exposed to 0.0625% bupivacaine, resulting from a simultaneous decrease and increase of cell viability, respectively (Figure 1) Cell viability was significantly (P = 0.022) decreased after 60 minutes of exposure to 1% LP Figure 1Viability of chondrocytes that were harvested from the metacarpophalangeal joints of 4 healthy adult horses determined with an MTT assay after 30 (A) and 60 (B) minutes of exposure to saline (0.9% NaCl) solution and culture media (control); 0.25% or 0.25% lidocaine with (LP) or without the preservative methylparaben; 1% Cell viability is reported as a percentage of cell viability for the control (100% [dotted line]) Each bar represents mean percentage cell viability and each error bar represents SD *Cell viability significantly (P < 0.05) differs between LA and control Citation: American Journal of Veterinary Research 82, 6; 10.2460/ajvr.82.6.478 Cell viability was significantly (P < 0.001) decreased after 30 minutes of exposure to 0.25% bupivacaine, compared with control, 0.125% bupivacaine, and 0.0625% bupivacaine (Figure 2) cell viability was significantly decreased after 30 minutes of exposure to 0.5% ropivacaine compared with control (P < 0.001) and 0.125% ropivacaine (P < 0.001) cell viability was significantly decreased compared with 0.5% LP (P = 0.029) and 0.25% LP (P = 0.026) Figure 2Viability of chondrocytes that were harvested from the horses in Figure 1 determined with an LDH assay after 30 (A) and 60 (B) minutes of exposure to various concentrations of various LAs. See Figure 1 for key Cell viability was significantly decreased after 60 minutes of exposure to 0.25% bupivacaine, compared with control (P = 0.005) and 0.0625% bupivacaine (P = 0.001), and significantly (P = 0.012) decreased after 60 minutes of exposure to 1% mepivacaine, compared with control (Figure 2) Cell viability was also significantly decreased after 60 minutes of exposure to 1% lidocaine compared with control (P = 0.004) and 0.25% lidocaine (P = 0.045) Exposure to 0.25% ropivacaine also significantly decreased cell viability compared with control (P = 0.047) and 0.125% ropivacaine (P = 0.001) Exposure to 1% LP significantly (P < 0.001) reduced cell viability Figure 3Viability of FLSs that were harvested from the horses in Figure 1 determined with an MTT assay after 30 (A) and 60 (B) minutes of exposure to various concentrations of various LAs. See Figure 1 for key After 30 minutes of exposure to 0.0625%, 0.125%, or 0.25% bupivacaine, cell viability did not significantly differ, compared with control, but viability was significantly (P = 0.017) lower for cells exposed to 0.25% bupivacaine versus 0.125% bupivacaine, resulting from a simultaneous decrease and increase in cell viability, respectively (Figure 3) Cell viability was significantly (P = 0.008) decreased after 60 minutes of exposure to 0.25% bupivacaine and significantly decreased after exposure to 1% mepivacaine compared with control (P = 0.015) and 0.25% mepivacaine (P = 0.042) After 30 minutes of exposure to 0.0625%, 0.125%, or 0.25% bupivacaine, cell viability was not significantly different, compared with control, but viability of cells exposed to 0.25% bupivacaine was significantly (P = 0.033) lower, compared with 0.125% bupivacaine (Figure 4) Cell viability was significantly (P < 0.001) decreased after 30 minutes of exposure to 1% mepivacaine After 30 minutes of exposure to 0.5% or 0.25% ropivacaine cell viability was significantly (P < 0.001) decreased and after 30 minutes of exposure to 0.5% ropivacaine Cell viability was significantly (P < 0.001) decreased after 60 minutes of exposure to 0.25% bupivacaine compared with control and 0.125% and 0.0625% bupivacaine After 60 minutes of exposure to 1% mepivacaine or 0.5% mepivacaine and after 60 minutes of exposure to 1% mepivacaine viability was also significantly (P < 0.001) decreased Cell viability was significantly decreased after 60 minutes of exposure to 0.5% ropivacaine compared with control (P < 0.001) and 0.125% ropivacaine (P = 0.02) Figure 4Viability of FLSs that were harvested from the horses in Figure 1 determined with an LDH assay after 30 (A) and 60 (B) minutes of exposure to various concentrations of various LAs. See Figure 1 for key Cell viability was significantly decreased after 30 minutes of exposure to 0.25% bupivacaine, compared with control (P < 0.001), 0.125% bupivacaine (P = 0.011), and 0.0625% bupivacaine (P < 0.001), and after 30 minutes of exposure to 0.5% ropivacaine, compared with control (P = 0.033; Figure 5) Thirty minutes of exposure to 1% LP significantly (P < 0.001) decreased cell viability Cell viability was significantly decreased after 60 minutes of exposure to 0.25% bupivacaine and after 60 minutes of exposure to 0.5% ropivacaine Figure 5Viability of FLSs that were harvested from the horses in Figure 1 determined with a TB assay after 30 (A) and 60 (B) minutes of exposure to various concentrations of various LAs. See Figure 1 for key the wells that contained ropivacaine appeared cloudy As the LA solutions were aspirated from the wells crystallization was evident in all wells that contained ropivacaine; crystallization was confirmed microscopically The amount of crystallization appeared to correlate with the concentration of ropivacaine with higher concentrations resulting in more crystals No further analyses of the crystals were performed and none of the other LAs caused crystallization The recommended volume of LAs to inject into a horse's joint is lower than or equal to the volume of synovial fluid within the joint,21–23 such that chondrocytes and FLSs are likely exposed to diluted LA in vivo versus the label concentration of LA The degree and rate of mixing of LA and synovial fluid are unknown but horses exposed to LAs for joint blocks during lameness examination are weight bearing and Consequent to the likelihood that an LA becomes diluted in a joint evaluated LA concentrations were adjusted to more closely mirror the in vivo LA concentrations in a joint after intra-articular injection; therefore results presented here may be more clinically relevant these findings suggest that maximum LA concentration in the synovial fluid after intra-articular injection of an LA would be achieved in < 2 hours cell exposure times of 30 and 60 minutes for each LA were chosen for optimal clinical relevance the standard concentration of commercially available formulations Results of the present study of horses showed that 0.0625% and 0.25% bupivacaine were also toxic to the chondrocytes and FLSs after exposure times of 30 and 60 minutes when the exposure time was extended to 2 hours and 1 intra-articular injection of 2% mepivacaine induces joint inflammation and collagen catabolism in horses whereas a toxic effect on equine chondrocytes was noted with 0.25% ropivacaine in the present study a toxic effect on human chondrocytes occurs after exposure to 0.75% ropivacaine but not to 0.5% ropivacaine Differences in concentrations at which LAs are toxic to chondrocytes and FLSs may be explained by the use of various methodologies for determining cell viability among studies crystals in the joints may cause microtrauma there the in vivo consequences of crystals cannot be assumed on the basis of the findings of the present in vitro study and the results of the present study revealed decreased in vitro viability of equine chondrocytes and FLSs at clinically relevant concentrations of LAs The cytotoxicity of various LAs was time and concentration dependent and the results highlighted the impact that the choice of LA may have on the viability of articular chondrocytes and FLSs of horses The most toxic LA was bupivacaine; therefore Mepivacaine and lidocaine were similar in their effect on cell viability Because of ropivacaine's tendency to crystallize in vitro at physiologic pH The time of chondrocyte and FLS exposure to various LAs is difficult to influence in vivo but because of the dose-dependent toxic effects use of the lowest effective dose of an LA for intra-articular anesthesia in clinical practice is recommended Funded in part by Boehringer Ingelheim Denmark A/S None of the authors have any financial or personal relationships that could inappropriately influence or bias the content of the article The authors acknowledge horse owners that permitted their horses for inclusion in the study 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide MTT cell proliferation assay kit (ab211091) Severe chondrolysis after shoulder arthroscopy: a case series Postarthroscopic glenohumeral chondrolysis Comparison of ropivacaine and bupivacaine toxicity in human articular chondrocytes and mepivacaine on human chondrocytes and cartilage Lidocaine exhibits dose-and time-dependent cytotoxic effects on bovine articular chondrocytes in vitro Comparison of the cytotoxic effects of bupivacaine and mepivacaine in equine articular chondrocytes Viability of equine chondrocytes after exposure to mepivacaine and ropivacaine in vitro Local anaesthetics or their combination with morphine and/or magnesium sulphate are toxic for equine chondrocytes and synoviocytes in vitro Changes in equine carpal joint synovial fluid in response to the injection of two local anesthetic agents In vivo effects of a single intra-articular injection of 2% lidocaine or 0.5% bupivacaine on articular cartilage of normal horses Effects of intra-articular administration of lidocaine and the preservative methyl parahydroxybenzoate on synovial fluid biomarkers of horses Human chondrocyte apoptosis in response to mechanical injury Chondrocyte apoptosis and nitric oxide production during experimentally induced osteoarthritis Chondrocyte-derived apoptotic bodies and calcification of articular cartilage Proc Natl Acad Sci U S A 1998;95:3094–3099 The effect of local anaesthetics on synoviocytes: a possible indirect mechanism of chondrolysis Knee Surg Sports Traumatol Arthrosc 2013;21:1468–1474 In vitro toxicity of local anesthetics and corticosteroids on chondrocyte and synoviocyte viability and metabolism Diagnosis and management of lameness in the horse The role and therapeutic implications of fibroblast-like synoviocytes in inflammation and cartilage erosion in rheumatoid arthritis Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill A bioluminescent cytotoxicity assay for assessment of membrane integrity using a proteolytic biomarker Biochemical synovial analysis and determination of synovial volume at distal joints of the forelimbs of horses Volume of the synovia in certain joint cavities in the horse Intra-articular administration of lidocaine plus adrenaline in dogs: pharmacokinetic profile and evaluation of toxicity in vivo and in vitro Mepivacaine: its pharmacological effects and their relationship to analytical findings in the horse Evaluation of chondrocyte death in canine osteochondral explants exposed to a 0.5% solution of bupivacaine The in vitro effects of bupivacaine on articular chondrocytes Chondrolysis after continuous intra-articular bupivacaine infusion: an experimental model investigating chondrotoxicity in the rabbit shoulder The effects of bupivacaine and neostigmine on articular cartilage and synovium in the rabbit knee joint Apoptosis and mitochondrial dysfunction in human chondrocytes following exposure to lidocaine and preservatives found in local anesthetics containing epinephrine The toxicity of local anesthetics: the place of ropivacaine and levobupivacaine Crystallization of local anesthetics when mixed with corticosteroid solutions Alkalinization and precipitation characteristics of 0.2% ropivacaine On the viscosity and pH of synovial fluid and the pH of blood Measurement of synovial fluid pH in normal and arthritic knees Subscribe to newsletters © 2025 American Veterinary Medical Association. All rights reserved. Powered by KGL PubFactory Company could build five facilities at the 1 million sq ft site Nordic data center company DigiPlex plans to build up to five data centers at a new campus near Copenhagen The company has acquired a 110,000 square meter (1,184,000 sq ft) plot of land in the Høje-Taastrup municipality to the west of Copenhagen and secured power contracts to support its development The project will be its second Danish data center site Register now for this week's global summit on data center sustainability DCD>Towards Net-Zero “We are seeing huge interest in sustainable data center development in the Nordic region and continue to invest to capitalize on this trend," said Wiljar Nesse "The acquisition of this major plot, plus the Norwegian land acquisition we announced last month further strengthens DigiPlex ability to rapidly meet the need for data center capacity from hyperscalers as well as local and international businesses requiring ultra-sustainable cost-effective colocation facilities." Nesse said that the company is ready to start construction and is in discussion with "a number of" potential international customers The five data centers will be water-cooled with the majority of water needs set to be met by onsite wells and rainwater The company plans to build a lake to collect rainwater and contribute to a storm-water basin DigiPlex said it has secured enough electricity supply for the first phase of its development but has the option to increase this to up to 100MW DigiPlex "will create development and invest in our local infrastructure and ecosystem," Høje-Taastrup mayor Michael Ziegler said "I’m also very pleased to announce that DigiPlex has kindly agreed to contribute to water reservoirs and to upgrade local roads as well as building new cycle paths This will benefit the whole community." Data Centre Dynamics Ltd (DCD), 32-38 Saffron Hill, London, EC1N 8FH Email. [email protected]DCD is a subsidiary of InfraXmedia On June 27th, Swedish train company Snälltåget sent its first night train from Stockholm to Berlin stopping in Høje Taastrup outside Copenhagen on its way to Germany This will be the first international overnight train route through Denmark since November 2014 when Swiss train service CityNightLine ceased service to Denmark Here’s what you need to know about the new night train connection from Copenhagen to Germany What time can I catch the train in Copenhagen The train stops in Høje Taastrup at 10:45 p.m. It drops off in Hamburg at 5:31 am and Berlin at 8:52 am the following morning, according to Snälltåget The return trip begins from Berlin at 7:02 pm and Hamburg at 11:26 pm arriving in Høje Taastrup at 6:38 am the following morning Image: Snälltaget Departures from Sweden will operate daily from June 27th until September 5th and then on Wednesdays and Saturdays until September 29th Departures from Germany will operate daily from June 28th until September 5th and then on Wednesdays and Saturdays from September 8th until October 2nd Prices vary depending on departure and class of comfort Prices are available via Snälltåget’s online booking system The most affordable option is the purchase of a basic reserved seat There is also the option to book a wider reclining seat The private compartment can convert from seat mode into sleep mode with three bunk beds on each side of the compartment Snälltåget is not accepting solo bookings in compartments Snälltåget honors valid Interrail Global Pass but also requires the purchase of a reservation which vary in price from 145 DKK to 1680 DKK The entire trip must take place within the validity period of your Interrail pass There are two restaurants aboard the train The night trains offer Wi-Fi and power outlets and each coach regardless of class has two toilets pets and bikes (except folding bikes) are not allowed on the journey In addition to experiencing Hamburg and Berlin, tourists can continue their journey by night train with ÖBB Nightjet a service the Austrian national railway announced in December 2020 Night trains from Hamburg connect to Vienna A French startup, Midnight Trains, is hoping to further expand Europe’s network of overnight trains in 2024, connecting cities in France, Spain, Portugal, Belgium, Germany, Denmark, and Scotland. The Guardian reports that ticket prices would be competitive with short-haul flights including hidden costs of baggage fees and transit to and from the airport What’s behind the return of Europe’s night trains Over the years, Europe’s night trains were phased out as the popularity of low-cost flights and long-distance buses increased, The Guardian reported it’s anticipated that tourists will have a greater interest in more sustainable forms of travel Night trains are a part of the European Commission’s plans to shift passengers toward rail service, as outlined in its Sustainable and Smart Mobility Strategy released in December 2020 The new push toward night trains has long been awaited by some Danes. In 2018, the Transport, Building and Housing Committee at Christiansborg received roughly 42,000 signatures demanding the return of night trains in Denmark “There is great interest in traveling by train and night train seen from an environmental perspective,” said Marco Andersson to reduce the environmental impact of the overnight train journey a SwimSwam partner Commit Swimming has Team Management Software Improved Meet Entry Flow in Commit What… La decisión tiene efecto inmediato tras una votación en una reunión extraordinaria del European Aquatics Bureau el 24 de abril April 21st, 2021 Europe, International, News The Danish Open concluded today at Taastrup Swimming Hall which means we now know the nation’s roster for the European Championships coming up in May This 5-day competition represented the final qualification opportunity for athletes and 24 were able to make the grade and be named to the roster for Budapest These swimmers will not only use the European Championships as an elite event in their own right but will also be able to continue striving to qualify for this summer’s Olympic Games The following swimmers have notched Olympic qualifying times to date: One rapidly-spreading technology that’s doing just that is vertical farming which uses LED lights and a heavily-controlled indoor environment to grow produce with dramatically less water or fertilizer than in traditional agriculture in an area called Taastrup outside of Copenhagen At 7,000 square meters (just over 73,000 square feet) it will be the biggest vertical farm in Europe Crops will grow in stacks 14 layers high and will use more than 20,000 LED lights The farm’s technology comes from a Taiwanese vertical farming company called YesHealth Group which partnered with Danish food tech company Nordic Harvest for this project Beyond the abundance of layers and lights, it takes automation to the next level; little robots on wheels will be tasked with delivering seeds to the various rows of stacked growing shelves. Sensors combined with smart software will monitor and process more than 5,000 different data points; a key one is the intensity of the LED light as it relates to the stage of growth the plant is in and the farm’s creators felt that using this sustainable source of energy was the optimal choice We’ve gotten used to being able to buy and eat whatever fruits and vegetables we desire at any time of year Produce that’s out of season costs us a little more at our local grocery store and it’s probably flown or shipped in from thousands of miles away but hey—sometimes you just want to make a cherry pie from scratch in the middle of winter Sign up to receive top stories about groundbreaking technologies and visionary thinkers from SingularityHub The supply chain to get these fresh foods from point A to point B is no small endeavor From keeping fruits or veggies cold and pest-free for the journey to making sure they arrive unblemished to using chemicals to keep them fresher for longer this system puts a lot of strain on both the environment and on the foods themselves they may not be able to grow everything under the sun—for now they’re mostly limited to greens like lettuce etc.—but they can grow the same quantity and quality of crops year-round and they’ll redefine the meaning of “eating local.” If enough of them pop up they could even help allow some farmland to be reforested According to Nordic Harvest’s website if it established more sites like Taastrup and grew greens in a space equaling the size of 20 soccer fields this would allow Denmark to become “self-sufficient in salads and herbs” rather than importing them from other countries; currently only 30 percent of Denmark’s consumption of these items is grown domestically Not only will Taastrup grow produce locally, it will grow it quickly. The facility plans to harvest the layered greens 15 times a year, for an output totaling 1,000 metric tons annually. “In this kind of growing method...you won’t be influenced by the climate, so you can [grow on] a new schedule,” said Stella Tsai The facility plans to start producing in the first quarter of next year and expects to be profitable next year too reaching its full 1,000-ton capacity by the end of 2021 Image Credit: Nordic Harvest Vanessa has been writing about science and technology for eight years and was senior editor at Singularity Hub. She's interested in biotechnology and genetic engineering, the nitty-gritty of the renewable energy transition, the roles technology and science play in geopolitics and international development, and countless other topics. Be Part of the FutureSign up to receive top stories about groundbreaking technologies and visionary thinkers from SingularityHub. SingularityHub chronicles the technological frontier with coverage of the breakthroughs danish artist thomas dambo has installed six open air treasure hunt for the public to experience and enjoy dambo’s huge wooden creatures are ‘hidden’ in rødovre all six sculptures have been carefully crafted from recycled scrap wood and have been built alongside the help of local volunteers ‘little tilde’ in installed in vallensbæk ‘little tilde’, ‘teddy friendly’, ‘thomas on the mountain’, ‘oscar under the bridge’, ‘hill top trine’, and ‘sleeping louis’ are hidden in ‘secret’ locations across the danish woodland. each of the six giants have been built by hand by dambo and a team of volunteers who sourced scrap wood from local fallen trees and broken down buildings the enormous figures can each be engaged and interacted with like ‘little tilde’ who hides 28 birdhouses inside its belly whose gaping mouth can be entered and played within.  the sculpture is made solely from local scrap wood scavenged by dambo and his team ‘teddy friendly’ is hidden in høje taastrup local trees have been used to create the figure’s ‘fur’ ‘thomas on the mountain’ can be found in copenhagen ‘thomas’ overlooks the municipality of albertslund the team had help from a group of young volunteers from a local school ‘oscar under the bridge’ is installed in ishøj the sculpture is made from scrap wood from a torn down watermill and broken pallets from local industries ‘hill top trine’ can be spotted in copenhagen visitors can crawl into the palms of her hands and overlook avedøresletten ‘sleeping louis’ takes a nap on a hill in a secret area in rødovre AXOR presents three bathroom concepts that are not merely places of function but destinations in themselves — sanctuaries of style Copyright © techoraco and its affiliated companies 2025 The campus will be constructed in Høje-Taastrup municipality to the west of Copenhagen in an area surrounded by industrial developments and is part of "The Finger-Plan" development' strategy of the Greater Copenhagen Area DigiPlex said it has secured enough electricity supply for the first phase with an option to increase this to as much as 100MW as the campus grows "We are seeing huge interest in sustainable data centre development in the Nordic region and continue to invest to capitalise on this trend,” said Wiljar Nesse plus the Norwegian land acquisition we announced last month further strengthens DigiPlex ability to rapidly meet the need for data centre capacity from hyperscalers as well as local and international businesses requiring ultra-sustainable "Through close collaboration with all parties we already have power agreements and all necessary building regulation approvals in place “We are ready to start campus construction and are already in discussion with a number of potential international customers." Five water-cooled data centres are planned with the majority of water requirements met by onsite wells and rainwater "We are very happy to welcome DigiPlex to Høje-Taastrup Their data centre campus will not only bring jobs but also add value to the municipality,” said Michael Ziegler “DigiPlex which is an environmentally sustainable datacenter will create development and invest in our local infrastructure and ecosystem “I'm also very pleased to announce that DigiPlex has kindly agreed to contribute to water reservoirs and to upgrade local roads as well as building new cycle paths DigiPlex plans to build a lake to collect rainwater for use in cooling as well as contribute to a storm-water basin to benefit the local community "Data centre developments such as DigiPlex' are exactly what we aim for to bring the advantages of the digitalisation to Danish economy,” commented Maria Tarp “The high-value services will cement Denmark's already established reputation as a perfect location for these enablers of the sustainable digital economy We are pleased to see DigiPlex expanding its current footprint in Denmark to now also include Høje-Taastrup.” who is selling the land said it was important that the new owner added value to the land and to the local community DigiPlex has a total of seven data centres in the Nordic region and opened new centres at Fetsund and Hobøl last year An additional centre is under construction at Fetsund and 100,000 m2 of land has been purchased for an additional campus outside Oslo at Treklyngen industrial park in Ringerike You have reached the limit for gifting for this month Text description provided by the architects. The Danish Meat Research Institute (DMRI) develops solutions for the international meat industry and provide consultancy both nationally and internationally. The building cements our position as the world's largest and leading international centre of excellence in research and innovation in meat and meat products, and with the new facilities, our research and development can step up even more towards new technologies, new products and new markets, says CEO Søren Stjernqvist, Danish Technological Institute. Courtesy of C.F. Møller ArchitectsThe DTI campus was originally designed by architect Vilhelm Wohlert in the 1970s. The complex is laid out in a spiral shape in a green landscaped setting, and the individual institutes are designed in a simple and austere architecture with red brick and exposed concrete lintels. The new building is based on the same simple design idiom, but with more modern twists such using pre-fabricated brick reliefs, and incorporating bay windows. Courtesy of C.F. Møller ArchitectsThe 6,600 m² building houses about 120 DMRI employees, and includes a research abattoir complete with cooking and smoking, ultra-modern microbiological and chemical laboratories (including laboratory facilities for the study of the occurrence of pathogenic bacteria in meat production), integrated robotic workshops, as well as offices and meeting facilities. Floor PlanA large atrium facilitates extrovert and open collaboration across the organization, and customers are already on arrival presented with the company’s activities, via glazed openings in the lobby, revealing workshops and office space. Møller Architects has designed the project with C.F The client is the Danish Technological Institute and the construction was carried out by Enemærke & Petersen (originally started by Pihl) You'll now receive updates based on what you follow Personalize your stream and start following your favorite authors If you have done all of this and still can't find the email Forty Turkish origin candidates were elected in the Denmark local elections held on Nov The local media reported that as many as 101 Turkish origin candidates competed in the election from several parties who was elected as a member of Höje-Taastrup Municipality Assembly in eastern Denmark told Anadolu Agency that foreigners have been facing misperceptions in Denmark and he would work to break this perception we are exposed to misperception by the media and society because we can not express ourselves,” he said we will have better results when we are in the municipalities and working closely with the mayor and other members of the council.” another Turkish origin candidate who was elected member of the Roskilde Municipality Assembly in Sjælland region said his victory would pave the way to take measures against racism He mentioned that hardcore racism was “taking place in Europe at this time" and added: “It is very important for us to be in the city councils we can make ourselves heard and take some kind of measure against racism." Reporting by Davut Colak; Writing by Sorwar Alam Travellers wishing to take the night train from Sweden to Austria can depart from Malmö at 14:55 on Thursdays between December 22nd and March 18th arriving in Salzburg the next morning at 09:12 with the train continuing through the Austrian alps to its final destination of Innsbruck The return train departs from Innsbruck on Fridays at 17:00 including all the stops between Sweden and Austria: Tickets start from between 999-1,499 Swedish kronor (€90-€135) per adult one-way depending on departure time with a fee of around 500 Swedish kronor/€45 depending on the service for a bed in a shared couchette or a fee of around 6,000 Swedish kronor/€545 for a private couchette There are substantial discounts for multiple people booking together: if two adults book together the second pays half price and children under 16 pay just 20 percent of the full price despite some journeys costing 999 kronor each way for a single adult or 1,901 kronor for a return trip the same journey costs 1,901 kronor each way for a family of two adults and two children under 16 putting return transport costs for a family of four at 3,802 kronor or €346 If this family book a private couchette both ways this adds around 10,000 kronor to the price putting the final sum at 13,998 Swedish kronor or around €1,275 for a return journey The night train service is aimed at skiers with a check-in ski service offered at 249 kronor per person per journey and a host of bus connections to popular skiing resorts from train stations in Austria The service is currently only offered as a return package: one ticket in each direction which mean's it's not possible to only book a ticket for Sweden to Austria without booking your return ticket from Austria to Sweden at the same time Snälltåget say that they may open up single journey bookings in the future if there is a lack of interest in return journeys It's also possible to book a ski package holiday with train journey, transfers, hotels and lift passes via Nortlander.se and Slopetrotter.se There is also a restaurant on board serving hot meals on porcelain See Snälltåget's website here for ticket booking and more information This website is using a security service to protect itself from online attacks The action you just performed triggered the security solution There are several actions that could trigger this block including submitting a certain word or phrase You can email the site owner to let them know you were blocked Please include what you were doing when this page came up and the Cloudflare Ray ID found at the bottom of this page A purple glow illuminates stacked boxes where lettuce herbs and kale will soon be sprouting at one of Europe’s biggest “vertical farms” which has just opened in a warehouse in an industrial zone in Copenhagen Fourteen layers of racks soar from floor to ceiling in this massive 7,000-square-metre hangar used by Danish start-up Nordic Harvest A general view of the ‘Nordic Harvest’ vertical plant farm The produce grown here will be harvested 15 times a year It is lit up around the clock by 20,000 specialised LED lightbulbs.  Plants cultivated at the vertical plant farm 'Nordic Harvest' little robots deliver trays of seeds from aisle to aisle The large aluminium boxes are mostly empty for now but lettuce and other leafy greens will soon be growing Some 200 tonnes of produce are due to be harvested in the first quarter of 2021 and almost 1,000 tonnes annually when the farm is running at full capacity by the end of 2021 founder and chief executive of Nordic Harvest That would make the Taastrup warehouse one of Europe’s biggest vertical farms.These urban facilities have unsurprisingly received a cool welcome from rural farmers who have questioned their ability to feed the planet and criticised their electricity consumption.  But Riemann stresses the environmental benefits of his farm with produce grown close to consumers and its use of green electricity “A vertical farm is characterised by not harming the environment by recycling all the water and nutrition or fertiliser,” says Riemann about 40 per cent of electricity consumption is wind-based we use 100 per cent energy from windmills which makes us CO2-neutral,” he adds While he wouldn’t disclose how much Nordic Harvest’s electricity bill comes to he said the power came with “wind certificates” registered on the Danish commodities exchange.  These legal documents guarantee that “the amount of electricity you consume in one year is equivalent to the electricity produced by numbered windmills offshore” vertical farms have taken off in Asia and the United States which is home to the world’s biggest The idea has slowly started to catch on in Europe used to plant seeds and check the plants while growing moving at the ‘Nordic Harvest’ vertical plant farm The robot moving past vertical racks at the vertical farm Urban farming could even allow land exploited by single-culture farming to be reforested “We moved the forests in order to have fields,” he laments noting that now farmers like him can bring “some of the food production back into the cities where you can grow on much smaller land and space optimised in height” His farm uses one litre of water per kilogramme of produce or 40 times less than underground farms and 250 times less than in fields The farm uses one litre of water per kilogramme of produce The names of his clients remain confidential According to a poll conducted by the Danish Farmers Union 95 per cent of Danes are ready to change their consumer behaviour to protect the environment.  “The EU regulation dictates that the word organic is linked to the word ‘soil’ so if you take soil out of the equation you can’t name it organic anymore,” he says But “we grow on the same terms as organic: we don’t use pesticides or insecticides” Aarhus University agriculture professor Carl-Otto Ottosen notes that Denmark “doesn’t have a space problem” and companies like Riemann’s are largely a novelty that won’t threaten Danish farming traditions where there’s no space to farm and where they want quality products,” he says Ottosen insists Danes are still more inclined to buy products based on “price please register for free or log in to your account A few moments ago Jesper Lindstrom Future Stars Academy Objectives Card leaked for FIFA 23 Ultimate Team We do not know if this card will effectively ever be released but according to FUT Camp The Lindstrom Future Stars will be released next few days during the Future Stars Promo Future Stars is the yearly celebration of the wonderkids poised to take The World’s Game by storm Former Future Stars have gone on to win league titles so each Special Player Item represents a footballer’s induction into an elite class of the brightest prospects in the game Every upgrade represents what each Future Star could become with upgrades that showcase them at their full potential.  Lindstrom has obtained an important boost to his base card stats: +13 Pace It also had a boost at the Skill Moves 4* and Weak Foot 4* too The card in question can be redeemed by completing these Weekly Objectives FIFA 23 is available from September 30th on PlayStation 5, Xbox Series X, PlayStation 4, Xbox One, PC, Steam and Nintendo Switch. Keep on following us also through our social Facebook, Twitter and Instagram for other news and Promo.