Rafael Jódar is having an exceptional season in American collegiate tennis
but his actions during the match between his team
The Spaniard was disqualified for hitting a ball into the fence
narrowly missing the Stanford team's bench where players and coaching staff were situated
This incident was deemed as aggressive behavior by the chair umpire
UVA’s Rafa Jodar is defaulted after hitting a ball into the fence towards the Stanford bench. Harsh and monumental punishment. https://t.co/GAjwYqwhMS
This news is an automatic translation. You can read the original news, Rafael Jódar, descalificado en un partido de la NCAA por un tremendo motivo
Rafa Jódar is part of the new generation of Spanish tennis players who are hoping to follow in the footsteps of Rafa Nadal
Rafa won the US Open Boys tournament and represented Spain in last year's Davis Cup
Jódar is currently on the US college circuit getting ready to make it in pro tennis
because I think there are many players not called Rafa
I think it's good to have these kind of players
Have you had the chance to meet the No.1 Rafa
but I would like obviously to meet him one time
He's also preparing for other tournaments for the rest of the season
he's been one of the greatest players in the tennis history
I joined my tennis club in Madrid called Club de Tenis Chamartín
Since that moment I started playing tennis just with my father
like many times that I had to maybe go somewhere
but at the end I enjoyed so much playing tennis since I was six years old
Tell me now about winning the US Open juniors
what did you feel and what did it feel like
I felt a good feeling about winning this title
because I had been working hard many years to lift this trophy
I also wanted to say thanks when I was doing the speech
also my coaches and my family who couldn't come to this
all the people in general who support me since I was younger
but I have two or three weeks in Madrid to be
Then you get an invitation to be part of the Spanish Davis Cup team
I knew I was coming to the Davis Cup before US Open
my flight tickets from New York to Valencia since the first days
of course after winning US Open junior is for me the best reward
I think it's just the first step of the journey
You have said that Rafa Nadal was your hero when you were growing up; I'm assuming you had posters on the wall of your bedroom
How much can you learn from watching those sort of players
I like those players who not just play tennis but
I'm very thankful for the Federation to give me the opportunity to be here
I want to thanks the organization and the Spanish Federation
and I thought this is really actually a little bit amusing
that's crazy that he achieved those titles before I was born
one of the best from my point of view of the history
1 thing you want to achieve in your career
RAFAEL JODAR: It's difficult to say something now
my dream is to be able to compete with these kind of players that I watch on TV
And maybe sometimes I can beat them; sometimes I can get some losses
to compete against them and be able to be in the big tournaments
there is a lot of attention now coming on to you and a lot of focus; is it easy to put that to one side
I think this tournament means that I can compete against the players who were born in my age
many more steps to reach the top of the tennis
I have to do many things well and keep pushing as I have ever done
How important do you think it is for you in your development that you're going to go to college in the United States
like are texting me after US Open that be happy
so I'm very happy that they give me that confidence
but maybe I think at University of Virginia the business school is really good
Is it by the side of your bed at home or in the lounge room
RAFAEL JODAR: I actually spent two hours in Madrid when I had to fly from New York to Madrid
When I arrive to Madrid (afterwards) I will have it in a better place (smiling)
Virginia has dropped three of its first four conference matchups
Facing the top team in both the ACC and the nation
Virginia struggled to gain momentum in a 4-1 loss
1-3 ACC) continued to play its new doubles pairings — freshman Rafael Jodar with graduate student James Hopper and junior Ty Switzer with freshman Jangjun Kim — in an effort to shake things up
the Cavaliers could not overcome the Demon Deacons’ (21-0
with Jodar securing Virginia’s only point.
Virginia’s new doubles pairing of Jodar and Hopper found itself locked in a grueling battle on Court 2
ultimately falling short in a tiebreak as Wake Forest secured the doubles point
the Demon Deacons applied pressure with Court 2’s lefty serve causing troubles for the Cavaliers
Jodar and Hopper quickly fell behind 1-4 as their attempts to rush the net and end points quickly proved unsuccessful
They had a chance to shift the momentum at 2-4
but Wake Forest held strong to maintain its advantage
sophomore Dylan Dietrich and junior Mans Dahlberg dropped their set 3-6
while Switzer and Kim on Court 3 managed to recover from a late break at 5-2 to close out a 6-3 win.
Jodar and Hopper faced a do-or-die moment on Jodar’s second serve
forcing deuce before Jodar delivered a big serve and Hopper put away three overheads to send the match to a deciding seven-point tiebreak
with Jodar crushing a massive inside-in forehand return to tie it 4-4
The Cavaliers then won two straight points to take a 6-4 lead
Hopper lost a serve-and-volley exchange at 6-5
allowing Wake Forest back into the tiebreak.
taking a 7-6 lead before Jodar responded with two huge serves to put the Cavaliers ahead 8-7
A missed return at 8-8 gave Wake Forest another opportunity
Hopper’s short pickup shot at the net led to a firing of forehands from Wake Forest to finish the match
giving it the early edge in the matchup.
with Jodar the lone standout in an otherwise difficult match
Even after a close doubles match where every point mattered
Jodar delivered an impressive straight-sets victory over the No
controlling the match from start to finish with a 6-2
His aggressive baseline play and consistency under pressure helped him secure the Cavaliers’ only singles victory of the day
providing a much-needed point in this very challenging matchup.
the rest of the Cavaliers found little success
but his match remained unfinished after he lost the second set 3-6
Hopper also pushed his opponent to the limit
winning a tight first set in a tiebreak before his match was halted at 7-6 (7-5)
Virginia struggled in the lower lineup as well
Kim and freshman Stiles Brockett were quickly overpowered
6-0 on Court 4 and Brockett suffering a 6-1
Dahlberg found his footing late in the second set but ultimately fell 6-0
while Wake Forest secured dominant victories to seal the match.
Virginia will look to regroup as it continues through ACC play
The Cavaliers showed flashes of promise and the competitiveness of their new doubles pairings
the depth and consistency across the lineup proved to be a deciding factor
Virginia will need to find ways to close out tight matches as it prepares for the matches ahead.
Virginia will hope to bounce back and secure a much-needed ACC win Friday when it faces Boston College at 3 p.m
Indieheads is one of many Contracted Independent Organizations at the University dedicated to music
though it stands out to students for many reasons
Indieheads President Brian Tafazoli describes his experience and involvement in Indieheads over the years
as well as the impact that the organization has had on his personal and musical development
Full Listings: Boys' Commits & Girls' Commits
Pulsed-power facility explores elusive warm dense matter regime lead image
At the intersection of the realms of condensed matter and hot plasma lies the regime of warm dense matter (WDM)
This describes matter too hot to be easily described by condensed matter theories
but too dense to fall under the umbrella of plasma physics
Probing this regime experimentally has also been challenging
leaving this temperature and pressure region largely unexplored
developed a pulsed power facility capable of applying multiple optical and electronic diagnostics and accessing a large thermodynamic range
“By reaching and probing unexplored thermodynamic states
we hope to guide theoretical research on density functional theory and average atom calculations in a temperature and density range where they do not match yet,” said author Benjamin Jodar
The researchers’ experimental facility consists of a metallic foil sandwiched by a sapphire anvil and heated by a kiloamp electrical pulse
This setup allowed the team to precisely control the density and pressure of the sample
they collected direct measurements of tension
and particle velocity on aluminum to evaluate its equation of state and DC conductivity
The authors plan to further improve their facility by expanding its functional range and increasing its diagnostic capabilities
“We are currently working on improving the capabilities to reach warmer temperatures and higher pressures,” said Jodar
work is in progress for implementing a temperature diagnostic that will help us assess the temperature of the plasma and its emissivity
We will also try to couple our experiment to a synchrotron source to probe the plasma electronic structure by X-ray absorption spectroscopy.”
Source: “A pulsed power facility for studying the warm dense matter regime,” by B. Jodar, L. Revello, J. Auperin, G. De Lachèze-Murel, A. Marizy, T. Géral, E. Lescoute, J.-M. Chevalier, C. Blancard and L. Videau, Review of Scientific Instruments (2024). The article can be accessed at https://doi.org/10.1063/5.0220607
holds up the championship cup after defeating Nicolai Budkov Kjaer
celebrates with her team members after defeating Wakana Sonobe
poses for a photo with runner-up Nicolai Budkov Kjaer
holds up the championship cup after defeating Wakana Sonobe
NEW YORK (AP) — Rafael Jodar of Spain rallied to win the U.S
beating top-seeded Nicolai Budkov Kjaer of Norway 2-6
12-seeded Jodar denied Budkov Kjaer a second straight major title
after he won Wimbledon to become the first Norwegian man to win a Grand Slam singles title at either the junior or professional level
said after his victory he wasn’t sure if he would still go to the University of Virginia as planned
of Britain won the girls’ title by beating No
The top-seeded team of Czech Maxim Mrva and Rei Sakamoto of Japan won the boys’ doubles title by edging Denis Petak and Flynn Thomas 7-5
Norway’s Emily Sartz-Lunde and Malak El Allami of Morocco captured the girls’ championship in a match tiebreaker
beating Julie Pastikova and Julia Stusek 6-2
The Longhorns advanced to the semifinals of the ITA Indoors for the second time in the last four years
to advance to the semifinals of the ITA National Indoor Championships on Saturday at the Styslinger/Altec Tennis Complex in Dallas
It marks the second trip to the semifinals in the last three years for the Longhorns
Eriksson grabbed the only break of the first set on a deuce point in the opening game even though Kim had two deuce point holds along the way
but Eriksson took it from there with a 6-0 run that included two deuce-point breaks for 4-1 and then on match point
Ojakaar opened the match with a break and then held at love for a 2-0 lead
He later broke again for 4-1 and consolidated at deuce for 5-1
Dahlberg collected the only break of the set for a 4-2 lead
and though the last three games were on serve for Dahlberg's win
Both players held their opening serve in the third set
but it was all Ojakaar from there as he set out on a 5-0 run to the win with none of those games reaching deuce
Bailly completed his three-set win over James Hopper
Three deuce points – all won by Hopper for two breaks and a hold – defined the first set
The first came in the second game for a break
which Hopper then consolidated for a 3-0 lead
Bailly answered with a 3-0 run of his own and had an opportunity for 4-0 on a deuce point
The final deuce point then resulted in a break for the set for Hopper
After Hopper held on yet another deuce point to start the second set
Bailly broke out on a 10-0 run to capture the second set and establish a 4-0 lead in the third
which were the last game of the second set and for the 4-0 lead in the third
The run might have lasted a game longer as the next one also went to deuce
but Hopper was able to break to begin a 3-0 run
The deuce point momentum finally went Bailly's way after that
as he broke and held at deuce to win the match
the first set stayed on serve until Rice broke on another for a 5-3 lead and served out the set
Braswell collected his first break on a deuce point for a 2-0 lead
however Rice broke back for 2-1 and then evened it
The set stayed on serve from there until Braswell broke again for a 5-3 lead and then held at deuce to go to a third
it was Rice who broke first on a deuce point for 2-0 and Braswell who broke back and evened it
The rest of then set was then on serve to the tiebreaker
but Braswell responded with a 4-0 run that he never relinquished despite Rice getting within one at 5-4 and 6-5
That's when Braswell came through with a final mini-break for the win
sending his teammates streaming onto his court
Two matches remained unfinished that were also in third-set tiebreakers with each team leading one of them. Freshman No. 11 Timo Legout was up on No. 44 Rafael Jodar, 4-6, 6-4, 6-6 (3-1), while junior No. 10 Sebastian Gorzny trailed No
Jodar opened it with a deuce-point hold and a break for a 2-0 lead
Legout then broke back and held to even it
but Jodar broke again for 4-2 and consolidated for 5-2
Legout got the second break back on a deuce point for 5-4 to get back on serve
Legout secured the only break for a 4-3 lead and later held on a deuce point for the set
after Legout held on a deuce point for 2-2
Jodar broke back and the rest of the set stayed on serve to a tiebreaker despite each player registering a deuce-point hold along the way
Legout won the first three points before play halted with the score 3-1
Gorzny's match featured two sets with tiebreakers
The first set stayed on serve the entire way with each player having one deuce-point hold
but Dietrich responded with a 3-0 run to tie it
but Gorzny came right back with a 3-0 run to win it
five of the first six games went to deuce but all stayed on serve
until Dietrich secured the only break for 5-3 and served it out
The third stayed on serve for the first 10 games even though there were three deuce points
Dietrich finally recorded the first break for a 6-5 lead
but Gorzny broke back to keep the match alive and go to the tiebreaker
Virginia claimed the first match with a 6-3 win by the No
75 pair of Dietrich and Dahlberg over Gorzny and Bailly at No
The match was decided on the only deuce point
which provided the Cavaliers the only break for a 4-2 lead
Virginia then clinched the point by the same score in a win for No. 65 Hopper and Rice over the No. 5 duo of Legout and sophomore Lucas Brown at No
After the Longhorns held on a deuce point for 2-2
including a deuce-point break that gave them a 5-3 lead
3 that was between Braswell and Ojakaar and Kim and Jodar
The Cavaliers broke in the opening game and held for a 2-0 lead
and although the Longhorns got the break back on a deuce point for 3-3
Virginia answered it for the lead when play stopped
The Longhorns will next have Sunday off before facing 1 seed No
2 Wake Forest in the semifinals at 3:30 p.m
Thanks for visiting
The use of software that blocks ads hinders our ability to serve you the content you came here to enjoy
We ask that you consider turning off your ad blocker so we can deliver you the best experience possible while you are here
The 18-year-old Spaniard has amazed in his first steps in the NCAA and is leaving magnificent impressions in his first professional tournament of the year
and the one chosen by Rafael Jódar is becoming increasingly common and tempting in the world of tennis
The 2024 Junior US Open champion decided to sign with the University of Virginia
He has only been there for three months and has already broken into the top-10 of the NCAA
making a sporadic leap to professionalism that is proving to be impressive
Exciting, hopeful, and of great interest. This is the only way to describe Rafael Jódar's progress in the early months of 2025
where he reached world number 4 and established himself as a promising talent with his title at Flushing Meadows
decided to postpone his move to professionalism to explore American collegiate tennis
- Why do more and more young tennis players choose to go through the NCAA before turning professional
It is increasingly common to see young players from around the world migrate to the land of the stars and stripes on tennis scholarships
The level of the NCAA is continuously improving
attracting talent from all over the world that sees this path as an ideal opportunity to learn English
receive academic training in globally recognized institutions
mature as individuals by stepping out of their comfort zone
meet new people and different working methods
and postpone professionalism until they are physically and mentally ready
Joao Fonseca himself had a pre-contract to compete for the University of Virginia
but his meteoric progress led him to turn professional at a young age
There are many examples of players who reach the elite after going through the NCAA
who dominated the competition in his rookie year and decided to join the ATP circuit
or Brandon Nakashima are other current examples of players in the top 100 who went through collegiate tennis
- Jódar has won 15 out of the 16 matches he has played in the NCAA
No one expected the Madrid native to stand out so much in such a short time
lost his first match against Connor Thompson
some against top-level opponents like the number 3 in the NCAA
His breakthrough has been so spectacular that he is already part of the country's top-10
Many wonder why Rafael is competing in a Challenger tournament in Morelos
the current rules between the NCAA and ATP allow college players to compete in two professional tournaments per year
Taking advantage of the break before the decisive phase in the fight for individual and team NCAA titles
the Madrid native decided to try his luck in this event
where he has already managed to claim two victories
Rafael Jódar appears much more physically mature
having strengthened himself and acquired explosiveness in his shots and movements on the court
His serve is much more damaging to opponents
and he is playing an aggressive style with his forehand as a key element
It will be interesting to see how long he combines the NCAA with these occasional appearances in professionalism because if the sensations continue to be positive
it wouldn't be surprising if his university days are shorter than expected
This news is an automatic translation. You can read the original news, La ilusionante progresión de Rafael Jódar, el universitario de moda
Sunday represented a huge win for Virginia
Freshman Rafael Jódar fired his second serve
There was some spin on it — just enough to pull the opponent
off his spot and give Jódar the advantage he needed
A quick rally ensued before Jódar put the ball away
pumped his fist and celebrated his win with a triumphant shout
It all came down to Court 6 and freshman Stiles Brockett
Brockett delivered — a big serve and a forehand to follow it up was all it took
His 6-3 win in the third set punctuated the Cavaliers’ (5-1
0-0 ACC) comeback win at home over the stacked Longhorns (6-1
exemplifying the grit and toughness for which this Virginia program is known
“[The team] came out and believed,” Coach Andres Pedroso said
This program has always prided itself in doing that.”
Coming off of a competitive but ultimately difficult loss Friday to No
the Cavaliers entered the match hoping for a win
Virginia will head to Dallas for the ITA National Team Indoor Championships
winning two sets before the Cavaliers could win one
then sophomore Dylan Dietrich and junior Mans Dahlberg lost a tight matchup 7-5
The freshman duo of Jódar and Jangjun Kim was tied at 5-5 when the Longhorns clinched the doubles point
“I told [the team] that in a college tennis season
you need to come back from losing the doubles point,” Pedroso said
Why not now?’ That’s what I told them after the doubles point
Kim played some incredible tennis en route to a 6-3
The Cavaliers were trailing 3-1 — Texas needed one more point to take home a win and serve Virginia its second ranked loss in 48 hours
Both Dietrich and Brockett won competitive second sets to keep the match alive after losing the first set
The Longhorns won five of six first sets — many in quick fashion — and it looked like their match to lose
needing three in a row to keep Virginia’s hopes alive
His heroics and clutch play kept the Cavaliers in the match
Dietrich earned the Cavaliers’ second point
In the final set he won all six of his service games
he lost two straight points but won the last point in clutch fashion to leave Virginia’s hopes in the hands of the two freshmen
Big serves and the ability to put points away from seemingly any position were
2 singles player in the country in junior Sebastian Gorzny
Jódar and Brockett both got off to strong starts
displaying incredible consistency and strong offensive play all day
before Brockett did what it took to send the Longhorns home empty-handed and extend the Cavaliers’ win streak against Texas to nine matches
Virginia was still missing one of its top players in freshman Keegan Rice
a win over the top-ranked team in the nation with a major tournament around the corner is an incredible result and bodes well as the team begins preparation for the ITA National Team Indoor Championships
the team will travel to take on Georgia Friday
0-0 SEC) are on a three-match losing streak
A clenched fist is exactly what Sunday's result felt like for Virginia
14 California that tested the resilience of the squad
8 Stanford 4-2 in a statement win at home Sunday
The weekend served as a full-circle moment for the Cavaliers (12-6
embraced lineup experimentation and found answers under pressure.
these tough times — you need to have them to have great times,” Coach Andres Pedroso said he told his team following the match against the Golden Bears
“I don’t know when those great moments will come
And this is a real test of our culture.”
In Friday’s battle against the Golden Bears (13-2
the Cavaliers found themselves in another close match against a top-20 team
but the Golden Bears proved just a little sharper in big moments
The doubles point slipped just out of the reach for Virginia
With yet another new lineup — graduate student James Hopper and freshman Keegan Rice playing Line 1
sophomore Dylan Dietrich and freshman Rafael Jódar playing Line 2
and juniors Mans Dahlberg and Ty Switzer debuting at Line 3 — the Cavaliers found promise but could not seal the deal.
Dietrich and Jódar rode their strong baseline games to a 6-4 win on Court 2
The top singles duo turned Line 2 doubles partners capitalized on their strong forehands
translating their strong singles play into doubles
“It’s different,” Dietrich said of partnering with Jódar
“[Jódar] and I play a quicker doubles — hit the ball big and try to finish points fast
It’s a different dynamic than with [Dahlberg]
where it’s more about building the point and being tricky at the net.”
while Dahlberg and Switzer were broken midway through and lost 3-6.
overcoming a controversial call late in the second set that nearly swung the momentum
The win gave Jódar his 14th-straight win and improved his record to 10-0 on the top singles court
6-3 and dominating points with his big forehands and a handful of aces.
freshman Roy Horovitz made his Line 4 singles debut
Still regaining strength after his ACL surgery
“He’s dying to play,” Dietrich said of Horovitz
“He’s probably the hardest-working guy on the team right now — in rehab
Hopper brought his trademark intensity and fight to Line 5
winning the first set 6-2 and then surviving an epic third-set tiebreak
drawing cheers from teammates and spectators
Dahlberg played one of the most intense matches of the day
where Dahlberg had a match point at 6-5 but ultimately fell 5-7
ending the match in the Golden Bear’s favor
5-3 ACC) and flipped the script — just as Pedroso had predicted.
“We’re going to make some adjustments from today and just continue to fight hard,” Pedroso said after the California loss
“I challenged the guys to be problem-solving machines
Another new doubles configuration — this time featuring Rice and Dietrich together for the first time — paid off immediately
The pair brought a fast-paced and aggressive style to Line 2
attacking returns early and controlling rallies to dictate points
Rice’s volley game complemented Dietrich’s steady presence from the back of the court
allowing the duo to roll to a dominant 6-2 win.
Hopper and Horovitz showed composure under pressure
The duo earned a crucial break at 5-5 and held serve to clinch the doubles point with a 7-5 victory — a strong debut pairing that blended Hopper’s experience with Horovitz’s quick energy at the net.
freshman Jangjun Kim reentered the lineup and immediately delivered a steady
Known for his steady play and smart point-building
Kim controlled tempo from the baseline and took advantage of short balls to close quickly at the net
6-4 win gave Virginia its first singles point and early breathing room in the match
6-4 and Line 4 saw the Cardinals edge out Hopper in a rollercoaster three-setter
He bounced back from a dropped second set by stepping inside the baseline and overwhelming his opponent with pace to win 6-3
He raced through the third set to put the Cavaliers back in front.
He surged through the second set 6-2 to force a decider
but the third was anything but smooth sailing
and keeping his footwork steady under pressure
breaking his opponent at 5-4 to clinch the match 4-6
6-4 and secure the 4-2 victory for Virginia.
and was tied 1-1 in the third when Rice sealed the win.
so uncommon in the last handful of seasons
But Sunday’s win felt like a monumental marker and a massive result
“Any culture can be great when we’re winning
and I know the guys are going to handle it great,” Pedroso said
The Cavaliers will look to build on Sunday’s win as they hit the road next weekend for a pair of ACC matchups
he reaches the 171st position in the ranking
The American went from being a qualifier in the preliminary rounds to winning the tournament
an absolute feat that confirms his upward trend in recent months
the 18-year-old Spanish talent Rafael Jódar surprised everyone with an incredible week at the Morelos Challenger (Mexico)
reaching the semifinals after three tough matches against Roberto Cid Subervi (6-3 5-7 6-2)
He eventually fell to the dangerous Marc Andrea Huesler
Jódar climbs 223 places and now stands at 688th position
Jack Draper moves up to sixth place after the 90 points relinquished by Casper Ruud
This news is an automatic translation. You can read the original news, Ránking ATP. Brooksby asciende 335 puestos y Jódar 223
Rafael Jódar bids farewell to a dream week at the Challenger Morelos 2025 in the semifinals
but the Spaniard left the Mexican tournament after falling to Marc Andrea Huesler
A very positive week for Jódar as he climbs 223 spots in the ATP Ranking
This news is an automatic translation. You can read the original news, Huesler remonta para acabar con el sueño de Jódar en Morelos
Rafael Jódar is the champion of the US Open Junior 2024
winning in a dramatic final against the great Nicolai Budkov Kjaer in just over 2 hours (2-6 6-2 7-6)
The Spaniard played a fantastic second set and achieved an epic comeback
demonstrating a fighting spirit worthy of another tennis player with the same first name
Rafa Jódar thus secured his first junior Grand Slam title against Budkov Kjaer
who already had this year's Wimbledon title in his trophy cabinet
17 years old and seeded 12th in the tournament
defeated players like Kaylan Bigun and Rei Sakamoto on his way to the title
captivating the audience with his tennis throughout the week
receiving all the affection possible and already inspiring a new "Vamos Rafa."
This news is an automatic translation. You can read the original news, Jódar conquista América en el US Open Junior 2024
First junior Grand Slam title for Rafael Jódar
who emerges to the world as a new big name in tennis: "I am very proud of myself."
Rafael Jódar arrived at the US Open Junior with a very clear objective
to achieve a feat that seemed difficult but possible
he faced the world number two and three in his category
American Kaylan Bigun and Japanese Rei Sakamoto
winners of the Australian Open and Roland Garros respectively
to top it off in a dramatic final against the world number one and reigning Wimbledon champion
With a celebration in true 'Bellingham' style in the moments following the title, Rafael Jódar spoke to the media with overflowing happiness for having clinched the US Open Junior 2024
- "All the work of my whole life has been proven here"
Jódar was asked to assess his exciting feat: "I am very happy
it has been a pleasure to play the final against Budkov Kjaer
all the work I have been doing throughout my life has been proven here
I was able to play my game when I needed it most
It has been the most important thing for me."
which I wasn't handling well in crucial points
So I just told myself that I had to believe in myself because I was in the US Open final and it was a gift for me
and I was able to perform better for the rest of the match."
"I won a similar match in the quarterfinals
and I managed to rise up because of all the people watching the match
I kept pressing and started playing more aggressively in decisive moments."
he was asked if he intended to accept the offer from the University of Virginia and continue his education
a matter he concluded with a smile: "Right now
This news is an automatic translation. You can read the original news, Jódar, en una nube tras ganar el US Open Junior: "Es como si estuviera soñando"
The Wimbledon Junior tournament features a 17-year-old Spaniard who is aiming to go far
excelled in his debut by defeating Tomasz Berkieta with a convincing score of 6-0 6-3
The recent winner of the international U18 Roehampton tournament arrived at Wimbledon in great form
well-prepared for this relatively new surface for him
the Madrid native strengthens his position by overcoming the fourth seed and remains the sole surviving Spaniard following the losses of Izan Almazán and Andrés Santamarta
This news is an automatic translation. You can read the original news, Rafael Jódar, la promesa española que ya está en cuartos de Wimbledon Junior 2024
Volume 12 - 2020 | https://doi.org/10.3389/fnsyn.2020.551691
This article is part of the Research TopicDendritic Spines: from Biophysics to NeuropathologyView all 10 articles
axonless granule cells (GC) mediate self- and lateral inhibitory interactions between mitral/tufted cells via reciprocal dendrodendritic synapses
Locally triggered release of GABA from the large reciprocal GC spines occurs on both fast and slow time scales
possibly enabling parallel processing during olfactory perception
Here we investigate local mechanisms for asynchronous spine output
To reveal the temporal and spatial characteristics of postsynaptic ion transients
we imaged spine and adjacent dendrite Ca2 +- and Na+-signals with minimal exogenous buffering by the respective fluorescent indicator dyes upon two-photon uncaging of DNI-glutamate in OB slices from juvenile rats
Both postsynaptic fluorescence signals decayed slowly
with average half durations in the spine head of t1/2_Δ[Ca2 +]i ∼500 ms and t1/2_Δ[Na+]i ∼1,000 ms
We also analyzed the kinetics of already existing data of postsynaptic spine Ca2 +-signals in response to glomerular stimulation in OB slices from adult mice
either WT or animals with partial GC glutamate receptor deletions (NMDAR: GluN1 subunit; AMPAR: GluA2 subunit)
In a large subset of spines the fluorescence signal had a protracted rise time (average time to peak ∼400 ms
This slow rise was independent of Ca2 + entry via NMDARs
since similarly slow signals occurred in ΔGluN1 GCs
Additional Ca2 + entry in ΔGluA2 GCs (with AMPARs rendered Ca2 +-permeable)
resulted in larger ΔF/Fs that rose yet more slowly
Thus GC spines appear to dispose of several local mechanisms to promote asynchronous GABA release
which are reflected in the time course of mitral/tufted cell recurrent inhibition
Since as in other synapses reciprocal release of GABA is Ca2 +-dependent (Isaacson and Strowbridge, 1998)
how could spine Ca2 + signals mediate asynchronous release
we explored several potential local mechanisms that might be involved in slow spine Ca2 + signaling and thus are directly related to the biophysical properties of individual spines
While the endogenous Ca2 + buffering capacity κE in GC spines is not unusually high (∼120) and thus cannot explain lingering Ca2 +, the Ca2 + extrusion from the spine cytosol is sluggish (rate γ∼500 s–1 at RT), which might support asynchronous output (Egger and Stroh, 2009)
However, these previous recordings of synaptic fluorescence transients were all performed with the Ca2 + indicator dye OGB-1 (100 μM, Kd = 200 nM). Therefore transients are substantially buffered and do not reflect true kinetics of Ca2 + signals (Egger and Stroh, 2009)
even though their observed decay times seem to fit well with the time scale of asynchronous release
Thus here we asked whether synaptic signals are indeed slow
also in comparison to AP-mediated transients
Finally, we noticed that in spite of similar endogenous Ca2 + dynamics and similar amplitudes of spontaneous and evoked synaptic transients in adult mouse and juvenile rat GCs (Egger et al., 2005; unpublished observations Egger and Stroh, Egger and Stroh, 2009; Abraham et al., 2010), postsynaptic Ca2 + signals in adult mouse GCs were yet slower with regard to their rise time (original data set from Abraham et al., 2010
in which kinetics had not been analyzed quantitatively)
This study had revealed a correlation between behavioral performance in a go/no-go odor discrimination task
and modifications of postsynaptic ΔCa2 + into the majority of GC spines via viral transfection
(2) mice with a deletion of the GluA2 AMPAR subunit (ΔGluA2; increased Ca2 + entry) which resulted in faster discrimination and thus a gain of function
and (3) mice with a deletion of the NR1 NMDAR subunit (ΔGluN1
Here we provide a quantitative analysis of the kinetics of the respective Ca2 + signals and the response probability and use the genetic pharmacology provided by the viral knockdown to infer possible mechanisms for the slow rise
here we aim to unravel the pyhsiological time courses of postsynaptic Ca2 + and Na+ signals in juvenile rat GCs in order to investigate their overlap with the previously established time course of asynchronous release
we describe an additional potential source of delayed release from adult mouse GC spines
Sagittal OB brain slices (thickness 300 μm) were prepared in artificial cerebrospinal fluid (ACSF
composition see below) following procedures in accordance with the rules laid down by the EC Council Directive (86/89/ECC) and German animal welfare legislation
Slices were incubated a water bath at 33°C for 30 min and then kept at room temperature (22°C) until recordings were performed
The extracellular ACSF was bubbled with carbogen and contained (in mM): 125 NaCl
Whole cell current clamp recordings were performed at room temperature (22 °C) and granule cells were held near their resting potential of −80 mV
Granule cells were filled with an internal solution containing the following substances (in mM): 130 K-Methylsulfate
and 1 mM SBFI (Na+-binding benzofuran isophthalate
United States) or 0.1 OGB-6F (Ca2 + indicator
The patch pipette resistance varied between 6 and 7 MΩ
For Na+ imaging experiments, electrophysiology and imaging were performed as in Ona-Jodar et al. (2017), and for Ca2 + imaging experiments as in Bywalez et al. (2015). Uncaging is also described in detail in Bywalez et al. (2015)
Imaging and uncaging were performed on a Femto-2D-uncage microscope (Femtonics
Verdi-pumped Ti:Sa lasers (Chameleon Ultra I and II respectively
The first laser was set either to 840 nm for excitation of OGB-6F or to 800 nm for excitation of SBFI in GC spines and dendrites
and the second laser was set to 750 nm for uncaging of caged glutamate
The two laser lines were directly coupled into the pathway of the microscope with a polarization cube (PBS102
As caged compound we used DNI-caged glutamate (DNI; Femtonics)
DNI was used at 1 mM in a closed perfusion circuit with a total volume of 12 ml
Caged compounds were washed in for at least 10 min before starting measurements
The uncaging laser was switched using an electro-optical modulator (Pockels cell model 350-80
Na+ and Ca2 + signals were imaged in line scanning mode with a temporal resolution of ∼1 ms
The scan position was checked and readjusted if necessary before each measurement to account for drift
The response probability is an estimate of the release probability and was calculated as the ratio of detected responses to the total number N of stimulations (average N = 14 ± 5 in WT)
Statistical comparisons were made with non-parametric tests (Wilcoxon test for paired and Mann-Whitney test for unpaired data sets)
Comparisons between WT GC responses and the ΔGluA2 and ΔGluN1 GC groups were made via pairwise Mann-Whitney tests with Bonferroni correction
Frequency distributions of parameters were compared with the Kolmogorov-Smirnov test
TPU-evoked Ca2 + entry into juvenile rat GC spines with low exogenous buffering
Imaging of TPU-evoked Ca2 + transients within GC spines with low exogenous buffering (100 μM OGB-6F)
(A) Scheme of experiment: whole cell recording from GC (filled with dye via pipette) and TPU at spine head
The pipette was also used for brief current injections to evoke somatic APs (sAP)
(B) Top: two-photon scans (z-projections) of three representative examples of individual spines filled with OBG-6F
Red and gray dotted line indicate line scan positions
Middle: respective averaged fluorescence transients (ΔF/F)TPU that were collected from line scans across the spine heads above (S
red) and the adjacent dendrite at the base of the spine neck (D
Blue dashed lines and star: time point of uncaging
Bottom: (ΔF/F)TPU transients averaged across experiments (Ca2 + imaging: n = 11 spines) with the same time axis
spine response in red and dendrite response in gray
The black trace in the Ca2 + imaging graph represents the averaged response (ΔF/F)AP to a backpropragating somatically evoked AP (recorded in n = 8 of the 11 spines)
(C) Cumulative plots of (ΔF/F)TPU amplitudes in dendrite and spine pairs (highly significantly different: P < 0.001
and of rise times and half durations t1/2 of (ΔF/F)TPU within the spine heads (mostly not detectable in the dendrites)
Right panel: half durations t1/2 of (ΔF/F)TPU within the spine heads (t1/2 could not be measured in most dendritic transients because of noise)
distance of the spine to the soma and spine neck length (means 99 ± 35 μm and 5.9 ± 3.3 μm respectively
The average rise time was 250 ± 130 ms and the half duration t1/2 = 890 ± 770 ms in the spines
including frequently observed plateau-like phases
Individual (ΔF/F)TPU signals in dendritic shafts were usually too noisy for kinetic analysis
As for TPU-evoked Ca2 + transients (Bywalez et al., 2015), there were no significant correlations between spine (ΔF/F)TPU amplitudes and distance to soma or spine neck length (Figure 2C)
and also no correlation between the amplitude ratio of spine/dendrite and spine neck length (not shown)
From these experiments we conclude that the time course of asynchronous components of GABA release triggered by unitary activation (Lage-Rupprecht et al., 2020) matches well with substantial and prolonged elevation of postsynaptic Na+ and Ca2 + concentrations in the GC spine
Late release therefore might result from local processing following unitary inputs to the reciprocal spine (see section “Discussion”)
Figure 3. Postsynaptic responses in adult WT, ΔGluA2 and ΔGluN1 GC spines. (A) Left: Scheme of experiment (modified from Abraham et al., 2010, their Figure 2)
Electrical glomerular stimulation and whole-cell recording of the resulting compound EPSP from a GC
including two-photon imaging of a responding spine and its adjacent dendritic shaft
Genetically modified GCs (ΔGluA2 and ΔGluN1) were identified by the expression of the fluorescent construct Kusabira-Orange
Right: line scans through the spine and dendrite during consecutive glomerular stimulations
that shows a slowly evolving Ca2 + transient confined to the spine head
with each trace imaged in a different spine
Same scales for ΔF/F and time as in (A)
Top transients with their associated compound EPSP recordings
Note the larger size and yet slower evolution compared to WT and ΔGluN1
Cumulative analyses of responses in adult mouse WT
(A) Estimated likelihood of observing a (ΔF/F)syn response upon glomerular stimulation (“response probability,” calculated as number of responses divided by number of stimulations)
Pairwise comparison (Mann-Whitney test) and Bonferroni: Pr WT vs
(B) Frequency distribution of (ΔF/F)syn response amplitudes for the three GC groups
but not from ΔGluN1 (P < 0.001 and P = 0.16
(C) Distributions of (ΔF/F)syn response time to peak for the three GC groups
The rightmost bar shows the responses where the peak might not yet have been reached within the scanning time window (up to 1,200 ms post stimulation)
(D) Frequency distribution of (ΔF/F)syn response time to peak for the three GC groups
with peaks possibly beyond scan window set to 1,200 ms (minimal time to peak)
but not from ΔGluN1 (P = 0.02 and P = 0.09
This slow rise was unrelated to Ca2 + entry via NMDARs, since similarly slow signals occurred in ΔGluN1 GC spines with reduced Ca2 + entry (Figures 3B, 4A–C; ΔGluN1 TTP 580 ± 260 ms
n = 13 events; 4 events with peak beyond scan
TTPmin = 740 ± 350 ms; no significant difference to WT TTPmin: Kolmogorov-Smirnov test P = 0.09)
The probability to observe such events in ΔGluN1 GCs (Pr = 0.18 ± 0.15
n = 7 spines) was also not significantly different from WT
the temporal extent of this asynchronous release was shorter than in the classical dendrodendritic inhibition experiments (maximal extent of ∼500 ms vs
>1 s) and therefore there might be additional mechanisms involved whenever GCs are activated more strongly
The NMDAR-mediated Ca2 + current into juvenile rat GC spines is expected to recede within less than 200 ms (e.g., Hestrin et al., 1990; Egger et al., 2005). It is thus on its own unlikely to mediate substantial asynchronous release far beyond the first 100 ms, even though the slow extrusion of Ca2 + from the cytoplasm may contribute to delayed release (Egger and Stroh, 2009)
To further unravel signaling downstream of the NMDAR and Nav activation during the local spine spike
we investigated the time course of postsynaptic Na+ and Ca2 + elevations with minimal exogenous buffering
Both ion species showed prolonged elevations for durations well compatible with asynchronous output
Further experiments are required to unravel such interactions
While this Pr value is no more than an estimate due to the small number of recorded responses and substantial noise in some experiments
we observed similar values also for recordings from ΔGluN1 and ΔGluA2 GCs
with the slight increase for ΔGluA2 possibly explained by the improved detectability of signals in these cells
Intriguingly, apparently slowly rising signals in GC spines may also be of presynaptic origin, e.g., due to late firing of principal neurons in response to glomerular stimulation (Kapoor and Urban, 2006; Gire et al., 2012; Giridhar and Urban, 2012)
this source might also contribute in the wake of glomerular stimulation; a correlation with late EPSPs is difficult to test because of the high spontaneous activity and low number of responses in our recordings
such delayed presynaptic activity is probably not a main source of slowly rising signals in our data set
since an enhancement of presynaptic signal contributions specifically in ΔGluA2 GCs appears rather unlikely
In conclusion, we find that several mechanisms such as delayed and slowly evolving excitation, slow removal of Ca2 + and perhaps extended local postsynaptic depolarization as indicated by the persistent elevation of Na+ may feed into asynchronous GC spine output. Since on the other hand there is also a fast, synchronous component of reciprocal release (Halabisky et al., 2000; Lage-Rupprecht et al., 2020)
GC spines are obviously capable of parallel processing on multiple time scales
a property that appears to be further refined with maturation
The raw data supporting the conclusions of this article will be made available by the authors
Ethical review and approval was not required for the animal study because according to German animal welfare legislation
our experiments in acute brain slices of rats and mice are classified as in vitro and do not require the approval of an ethics committee
monitored and certified by the authorities with regard to animal handling and the preparation process
which involves anesthesia and decapitation
Rat granule cell Ca2 + imaging was performed by VL-R
mouse viral injections by NA and mouse granule cell Ca2 + imaging by VE
All authors except for TOJ contributed to editing the manuscript
This study was funded by the BMBF (German Ministry of Education and Research
FKZ 01GQ1502; VE) with additional equipment funding by DFG-SFB 870 (Deutsche Froschungsgemeinsschaft
Regensburg University Library provided the open access publication fees
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest
Pietryga-Krieger for expert technical assistance
Gerkau (Heinrich Heine University Düsseldorf) for initial help with Na+ imaging
Synaptic inhibition in the olfactory bulb accelerates odor discrimination in mice
Maintaining accuracy at the expense of speed: stimulus similarity defines odor discrimination time in mice
Similarity and strength of glomerular odor representations define a neural metric of sniff- invariant discrimination time
Google Scholar
Rhythm sequence through the olfactory bulb layers during the time window of a respiratory cycle
Local postsynaptic voltage-gated sodium channel activation in dendritic spines of olfactory bulb granule cells
Calcium extrusion mechanisms in dendrites of mouse hippocampal CA1 inhibitory interneurons
Fast neurotransmitter release triggered by Ca influx through AMPA-type glutamate receptors
Analysis of relations between NMDA receptors and GABA release at olfactory bulb reciprocal synapses
CrossRef Full Text | Google Scholar
Postnatal development of dendrodendritic inhibition in the Mammalian olfactory bulb
Google Scholar
Synaptic sodium spikes trigger long-lasting depolarizations and slow calcium entry in rat olfactory bulb granule cells
Calcium buffering in rodent olfactory bulb granule cells and mitral cells
Mechanisms of lateral inhibition in the olfactory bulb: efficiency and modulation of spike-evoked calcium influx into granule cells
Dendrodendritic synaptic signals in olfactory bulb granule cells: local spine boost and global low-threshold spike
Dynamic optimization of odor representations by slow temporal patterning of mitral cell activity
Independent control of gamma and theta activity by distinct interneuron networks in the olfactory bulb
Mitral cells in the olfactory bulb are mainly excited through a multistep signaling path
Mechanisms and benefits of granule cell latency coding in the mouse olfactory bulb
Google Scholar
Neuronal pattern separation in the olfactory bulb improves odor discrimination learning
Calcium influx through NMDA receptors directly evokes GABA release in olfactory bulb granule cells
Contribution of a calcium-activated non-specific conductance to NMDA receptor-mediated synaptic potentials in granule cells of the frog olfactory bulb
Asynchronous GABA release generates long-lasting inhibition at a hippocampal interneuron–principal neuron synapse
Mechanisms generating the time course of dual component excitatory synaptic currents recorded in hippocampal slices
CrossRef Full Text | Google Scholar
Mechanisms governing dendritic gamma-aminobutyric acid (GABA) release in the rat olfactory bulb
Olfactory reciprocal synapses: dendritic signaling in the CNS
CrossRef Full Text | Google Scholar
Ca2+ ion permeability properties of (R,S) alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptors in isolated interneurons from the olfactory bulb of the rat
Enhancement of asynchronous release from fast-spiking interneuron in human and rat epileptic neocortex
doi: 10.1146/annurev-physiol-021113-170338
long-latency activity in the olfactory bulb granule cell network
The sniff as a unit of olfactory processing
Presynaptic NMDA receptors cooperate with local action potentials to implement activity-dependent GABA release from the reciprocal olfactory bulb granule cell spine
Google Scholar
Interplay between local GABAergic interneurons and relay neurons generates gamma oscillations in the rat olfactory bulb
A strict correlation between dendritic and somatic plateau depolarization in the rat prefrontal cortex pyramidal neurons
Sodium dynamics in pyramidal neuron dendritic spines: synaptically evoked entry predominantly through AMPA Receptors and removal by diffusion
Mondragão
Extrusion versus diffusion: mechanisms for recovery from sodium loads in mouse CA1 pyramidal neurons
Dendritic integration in olfactory bulb granule cells: threshold for lateral inhibition and role of active conductances upon simultaneous activation
Axonal sodium channel NaV1.2 drives granule cell dendritic GABA release and rapid odor discrimination
Disruption of GABAA receptors on GABAergic interneurons leads to increased oscillatory power in the olfactory bulb network
Two-photon Na(+) imaging reports somatically evoked action potentials in rat olfactory bulb mitral and granule cell neurites
Google Scholar
Granule cell excitability regulates gamma and beta oscillations in a model of the olfactory bulb dendrodendritic microcircuit
Odor representations in the olfactory bulb evolve after the first breath and persist as an odor afterimage
Google Scholar
Synaptically driven state transitions in distal dendrites of striatal spiny neurons
Regulation of dendritic calcium release in striatal spiny projection neurons
Theoretical reconstruction of field potentials and dendrodendritic synaptic interactions in olfactory bulb
An olfactory cocktail party: figure-ground segregation of odorants in rodents
NMDA receptor-mediated Na+ signals in spines and dendrites
Two-photon Na+ imaging in spines and fine dendrites of central neurons
The life cycle of Ca2+ ions in dendritic spines
CrossRef Full Text | Google Scholar
Dendrodendritic inhibition in the olfactory bulb is driven by NMDA receptors
Regulation of synaptic timing in the olfactory bulb by an A-type potassium current
Google Scholar
NMDA receptor-dependent synaptic activation of TRPC channels in olfactory bulb granule cells
Faithful expression of multiple proteins via 2A-peptide self- processing: a versatile and reliable method for manipulating brain circuits
An improved measurement of the Ca(2+)- binding affinity of fluorescent Ca(2+) indicators
Gamma-frequency oscillations: a neuronal population phenomenon
regulated by synaptic and intrinsic cellular processes
Speed and accuracy of olfactory discrimination in the rat
PubMed Abstract | CrossRef Full Text | Google Scholar
Downregulation of parvalbumin at cortical GABA synapses reduces network gamma oscillatory activity
Synchronous and asynchronous modes of synaptic transmission utilize different calcium sources
Google Scholar
Population imaging at subcellular resolution supports specific and local inhibition by granule cells in the olfactory bulb
NMDA channel regulation by channel-associated protein tyrosine kinase src
Gain control of NMDA-receptor currents by intracellular sodium
PubMed Abstract | CrossRef Full Text | Google Scholar
Rose CR and Egger V (2020) Local Postsynaptic Signaling on Slow Time Scales in Reciprocal Olfactory Bulb Granule Cell Spines Matches Asynchronous Release
Copyright © 2020 Ona Jodar, Lage-Rupprecht, Abraham, Rose and Egger. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY)
distribution or reproduction in other forums is permitted
provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited
in accordance with accepted academic practice
distribution or reproduction is permitted which does not comply with these terms
*Correspondence: Veronica Egger, VmVyb25pY2EuRWdnZXJAdXIuZGU=
†Present address: These authors share first authorship
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations
Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher
94% of researchers rate our articles as excellent or goodLearn more about the work of our research integrity team to safeguard the quality of each article we publish
3-ranked team in the nation (Ohio State) on Friday
1 team in the country in their next match less than 48 hours later
The top-ranked Longhorns won the doubles point with relative ease and then won the first set in five of the six singles matches
All of those indicators seemed to point towards a second-straight home loss for the No
Andres Pedroso's Cavaliers showed incredible toughness and battled back for a thrilling 4-3 comeback victory over Texas on Sunday afternoon at Boar's Head Sports Club in Charlottesville
The Longhorns immediately had the Hoos on their heels in doubles play
winning the top two courts 6-2 and 7-5 to take a 1-0 lead
Jangjun Kim made short work of Sebastian Eriksson 6-3
6-3 on court 5 to get the Cavaliers on the board at 1-1
it seemed the match was headed firmly in the direction of the Longhorns
Jonah Braswell held off Mans Dahlberg in the second set to win 6-0
6-4 on court 4 and then James Hopper fell to Pierre-Yves Bailly 6-2
moving Texas within one point of clinching the match at 3-1
Texas had plenty of opportunities to secure that last point
having won the first set on each of the other three courts still in play
But Stiles Brockett extended his match on court 6 against Lucas Brown with a 7-5 win and then
UVA's freshman phenom Rafael Jódar saved three match points and won the second set against Timo Legout
3-ranked men's singles player in the country
Dylan Dietrich rallied after losing the first set to beat Sebastian Gorzny
2-ranked men's singles tennis player in the country
Rafael Jódar sustained the momentum from the second set tiebreaker win into the third set and raced past Legout to win the match 3-6
a victory which evened the overall score of the match to 3-3
That left the fate of the match to be decided on court 6
where Stiles Brockett defeated Lucas Brown 4-7
6-3 to clinch the match and complete the comeback victory for the Cavaliers
WAHOOOOOWAA!!!Final Score5⃣ Virginia 4, 1⃣ Texas 3The Cavaliers come back to take down No. 1 Texas #GoHoos pic.twitter.com/vsBG3P0EHv
The three men's tennis teams that played at Boar's Head this weekend are some of the best in the country
Not only are they each ranked in the top five right now
but Virginia defeated Texas and Ohio State in the semifinals and finals in 2023 to win back-to-back national titles
losing in the quarterfinals to Wake Forest
but Texas and Ohio State both advanced to the Final Four and the Longhorns wound up losing to TCU in the National Championship
Sunday's comeback victory over Texas shows that Virginia is very ready to compete strongly for another national title this spring
Virginia (5-1) will head to Athens for a road match at Georgia on Friday at 6pm ET before traveling to Dallas for the ITA Team Indoor Championships the following week
The content on this site is for entertainment and educational purposes only
Betting and gambling content is intended for individuals 21+ and is based on individual commentators' opinions and not that of Sports Illustrated or its affiliates
All picks and predictions are suggestions only and not a guarantee of success or profit
If you or someone you know has a gambling problem
crisis counseling and referral services can be accessed by calling 1-800-GAMBLER
Luis Jodar is Chief Medical Affairs Officer for Global Vaccines and Antivirals at Pfizer Inc
Jodar heads Pfizer’s vaccines medical development
clinical and scientific affairs worldwide comprising around 200 MD
Jodar has held different positions at Pfizer including Vice President
Medicines Development Group and Scientific Affairs; Head of Vaccines
Medical Affairs for Emerging Markets and Executive Director for Clinical and Scientific Affairs for the Asia Pacific (AP) region at Wyeth
Jodar was Deputy Director General at the International Vaccine Institute (IVI) in Seoul
an international organization established by the United Nations for the development
introduction and use of new vaccines and adjunct professor at Seoul National University
he was responsible of directing the IVI’s Translational Research Division which conducts programs of interdisciplinary research
including pre-licensure and post-licensure clinical trials
studies of the economics of vaccine introduction
sociobehavioral and policy research on vaccines against cholera
Jodar worked at the World Health Organization (WHO) leading the global vaccine research and introduction of meningococcal vaccines
activities related to adverse events allegations and quality
safety and correlates of protection of vaccines
Previously he was the focal point of the Task Force for Vaccines and Viral Diseases at the European Commission in Brussels
Jodar is a neuroimmunologist with doctoral and post-doctoral training in Madrid
Jodar has worked in vaccine-related programs in more than 50 countries around the world including developing countries in Africa
published in the most accredited peer-review journals (e.g
and served on a number of advisory groups on vaccines to WHO
ADVAC and Columbia University and has a long track-record in launching and coordinating public private vaccine development partnerships to accelerate the development
introduction and commercialization of vaccines of public health importance for developing and middle-income countries having received more than $100M in grants
He has also been awarded with several honors including the “cross of officer of the order of civil merit” from the King of Spain for his work in vaccines and vaccination in developing countries
This information—including product information—is intended only for residents of the United States
The products discussed herein may have different labeling in different countries
who will be a key contributor next season and beyond
In 2023, Virginia was the national champion. This year, it lost in the ACC Championships and failed to advance to the NCAA Semifinals
despite an underwhelming finish this season
the future is incredibly bright for Virginia men’s tennis
The team has plenty of returning talent that will be complemented by a stellar class of incoming recruits
After advancing past the NCAA Super Regional to the NCAA Quarterfinals May 10
2 Virginia men’s tennis pushed to keep momentum going in the hopes of defeating No
6 Wake Forest and advancing to the NCAA Semifinals
the Cavaliers could not keep up with the Demon Deacons and fell to them 4-1 May 16.
Virginia faced Florida State — an opponent ranked lower than them that had managed to upset two strong teams before coming to the championship
The Seminoles had defeated both the second and third seed teams before facing the Cavaliers
so they had built strong momentum that would have been hard to defeat by any team.
The loss to Florida State was notably a close contest
The results for the entire ACC Tournament came down to the third set on the top court between two top-10 players in the nation — then-No
Returning to the NCAA Tournament, which is always seen as a marathon of a competition, the Cavaliers had initially started very strongly. They defeated both NJIT and VCU 4-0 in order to advance to the NCAA Round of 16
completely shutting out their opponents to ensure their victories
Advancing to the NCAA Quarterfinals was also relatively easy for Virginia
once the Cavaliers arrived at the NCAA Quarterfinals match against Wake Forest
Their top-ranked singles player had to be scratched from the lineup due to illness
affecting both the doubles and singles lineups for the matches.
Many of the singles courts had to go to a third set to decide the match
so the results were similar to the ACC Championship — Virginia pushed to win each court but unfortunately were defeated in the end.
it is going to be hard to replace all of the fantastic athletes that are finished with their collegiate career — Rodesch
senior Alexander Kiefer and graduate student Edoardo Graziani
this will allow some new players to step up and fill the roles that are opening up
Dietrich will continue to improve after a stellar rookie campaign
as he advanced to the NCAA Singles Round of 16 before ultimately falling to No
On top of his impressive achievement of making it far individually
Dietrich was also named ACC Freshman of the Year April 25.
Another player that has been pretty consistent all season — and still has a few more years of eligibility — is sophomore Måns Dahlberg
Dahlberg had some impressive feats this season — going 8-1 in singles in ACC play and having his first win against a top-100 ranked singles player
28 sophomore Jonah Braswell of Texas.
With these two consistent individuals returning in the fall to help lead the team to more victories
that these two might not be enough to fill the gap that will be left by the five departing players
it will be important that Coach Andres Pedroso takes advantage of his top-ranked recruiting class for the 2024-25 season.
A few of the athletes that are a part of this renowned incoming class are Joao Fonseca
1 in the ITF Junior Rankings in 2023 and has reached a rank of No
226 globally despite only being 17 years old
Jodar and Rice have also been nationally ranked — No
32 respectively — and help round out the internationally diverse group.
With key players returning and new additions joining the team
it will be important for everyone to work on building skills and confidence in the offseason in order to maintain the reputation that the Cavaliers have as being a men’s tennis powerhouse.
The dates displayed for an article provide information on when various publication milestones were reached at the journal that has published the article
activities on preceding journals at which the article was previously under consideration are not shown (for instance submission
All content on this site: Copyright © 2025 Elsevier B.V.
Science of the Total EnvironmentCitation Excerpt :Nevertheless
the hydrological impact of such precipitation decrease is not as simple as it looks at first glance
As a result of temperature trends observed in Central Chile (Burger et al.
as snowmelt generates low runoff flows that increase their infiltration and hence augment aquifer recharge (Jódar et al.
The joint impact on the decrease of both rainfall and snowfall
together with less return flows when irrigation is reduced
derive from the current megadrought developed in central Chile
Science of the Total EnvironmentCitation Excerpt :These high groundwater contributions to the total streamflow have been also observed in high mountain karst aquifers
which are known to store and transmit large volumes of water (Somers and Mckenzie
(2018) reported a contribution of 87% in the northern Alps on the Germany/Austria border
(2020) reported a contribution of 75% in the Ordesa and Monte Perdido National Park
which constitutes the highest karst system in Western Europe
Contrary to what happens in these karst systems
the permeable outcrops in the Bérchules watershed correspond almost exclusively to weathered materials (Fig
Journal of HydrologyCitation Excerpt :Karst aquifers are valuable groundwater resources that provide fresh water to approximately 25% of the human population (e.g.
the mountainous karst aquifers in the Mediterranean region including Pyrenees (e.g.
2014) are predominately used for drinking water and agricultural activities
Since these mountainous karst aquifers receive a large proportion of the precipitation as snow(Fayad et al.
they are currently more vulnerable to the climate-induced impacts than the relatively lower altitude karst aquifers
particularly considering the increased temperature over the Mediterranean regions (Alpert et al.
Jodar Performance, Race Part Solutions‘ in-house brand
has a lot of innovative products and specializes in those hard to find and often overlooked high performance racing tools and components that make fabrication easier
With commonly available fuel filters and distribution blocks maxing out at -10 AN
Jodar Performance’s fuel components are stepping it up to a larger size
“We’ve expanded our fuel distribution components with -12 AN Y-blocks and fuel filters
along with all our other components like injector bungs and specialized fuel fittings,” stated John Kerr of Jodar Performance
With the introduction of -12 AN fuel distribution components
fuel system options for drivers with high horsepower engines that demand a lot of fuel have opened up immensely
Instead of running two or more -8 AN lines for a fuel system
a single -12 AN line can be used to distribute fuel while also eliminating clutter and confusion
Another couple of cool innovative parts from Jodar Performance are their blow-off valves
They have a 50mm and 104mm blow-off valve that are great for high horsepower and tight spaces
and help eliminate clutter without reducing flow
“The 50mm blow off valve is very compact
making it a great option for tight engine bays where there isn’t a lot of clearance,” explains Kerr
“The 104mm BOV can replace smaller dual singles and still keep enough flow capacity.”
Build your own custom newsletter with the content you love from Dragzine
We will safeguard your e-mail and only send content you request
We'll send you the most interesting Dragzine articles
We promise not to use your email address for anything but exclusive updates from the Power Automedia Network
La Hermandad de la Misión ha hecho público que debido a la elección
de la Madrugada del Viernes Santo como jornada prioritaria para realizar la estación de penitencia a la S
siendo la tarde del Viernes Santo la segunda opción
la Banda de Cornetas y Tambores ‘Nuestra Señora de la Asunción’ de Jódar (Jaén) no podrá acompañar al único paso de la cofradía la próxima Semana Santa
que acompañará en 2021 a Cristo Rey y al Santísimo Cristo del Amor
tampoco pudo estrenarse el pasado Sábado de Pasión detrás de Ntro
Padre Jesús de la Misión Redentora debido a la suspensión de los desfiles procesionales de Semana Santa provocada por la crisis del COVID-19
Tu dirección de correo electrónico no será publicada
Los campos obligatorios están marcados con *
Δdocument.getElementById( "ak_js_1" ).setAttribute( "value"
Spain has produced some of the most legendary tennis players
Carlos Alcaraz is one active name on the ATP Tour who still has multiple years of his prime remaining
the 21-year-old is no longer in conversations regarding the future of tennis in Spain
This tag has now been awarded to Rafael Jodar
Jodar has become one of the most popular names in Spain
The 17-year-old first became the talk of the town after winning the Juniors US Open 2024
The 12th seed made headlines for defeating the #2
Rafael Jodar comes through the ultimate path to the US Open Boys’ title! pic.twitter.com/HlSZ8IM7NO
— US Open Tennis (@usopen) September 7, 2024
As a result of this victory, the Madrid native has been invited to Malaga to help the Spanish team led by Alcaraz prepare for the ongoing Davis Cup 2024
Clips of Jodar rallying with the ATP World No.3 have gone viral
and fans are gushing over the two youngsters
( copadavis en instagram) pic.twitter.com/R8nn8k0Shb
— Carlos Alcaraz Italia (@alcaraz_italia) September 12, 2024
Besides the two most significant moments of his career, enthusiasts are also lauding the youngster for his mentality. During a recent interview with Punto de Break
the teenager remained humble and put in the hard work rather than allowing the victories to get to his head
the 2006-born prodigy is choosing to “maintain the same humility” before all the success
Important people like (Alvaro) Morata have started to follow me
but I know I have to keep my feet on the ground
This is an important victory that will give me a lot of motivation to keep going
but there are things that must remain the same
I must maintain the same humility and without believing myself to be someone I am not
that is my goal right now,” Jodar said (translated from Spanish)
While the youngster doesn’t “care” about the comparisons to Rafael Nadal or Alcaraz
from what clips from their training camp suggest
captain David Ferrer is seemingly grooming him to become the next big Spanish player on the ATP Tour
it might be quite a while before we see Jodar becoming a regular name on the tour
Having signed the letter of intent to attend the University of Virginia from this year onwards
he hopes to develop playing in the American college circuit for the next year and beyond
Post Edited By:Sampurna Pal
Advait Jajodia
an NBA and Tennis journalist for The SportsRush
has had a passion for both sports for over a decade
and Rafael Nadal pushed him to gain a profound understanding of the sports
With a background as a multi-sport athlete
Advait uses his experience on the hardwood and the court to offer insightful analysis
Over four years of dedicated sports journalism has equipped the 22-year-old with a unique perspective
reflected in his prolific portfolio of 4,700+ articles
Day 13 of the 2024 US Open will feature the summit clashes of the Juniors division for both the boys and girls
The four players involved in the two title fights will be keen to get their hands on the junior US Open title which will help them to make a mark in professional tennis in the future
On the side of the boys, reigning Wimbledon champion Nicolai Budkov Kjaer will be in action against Rafael Jodar of Spain
British Mika Stojsavljevic will take on Wakana Sonobe of Japan in the girls' final
Let's look at the two Junior finals slated to take place on September 8
Top seed Nicolai Budkov Kjaer will look to win his second Junior Major title in 2024 when he takes on 12th-seeded Rafael Jodar of Spain in the final of the 2024 US Open
The Norwegian has already won the Junior Wimbledon title this year and also reached the semi-final of the Australian Open
where he lost to eventual champion Rei Sakamoto
Kjaer put in a dominant performance to defeat Charlie Robertson 6-3
Rafael Jodar has gradually improved his performances at the Junior Majors this year. After not playing at the Australian Open, the Spanish teen reached the third round at the French Open
He followed it up by reaching the quarterfinals at Wimbledon
Jodar caused a massive upset when he defeated third seed and the current Australian Open boys singles champion Rei Sakamoto in the semi-final
Kjaer will be the favorite to win the title
The girl's final at the 2024 US Open will see seventh-seeded Wakana Sonobe face off against the unseeded Brit Mika Stojsavljevic
The British player is having the best performance of her junior career so far at this season's US Open
She defeated the top seed and the runner-up at this year's Junior Australian Open and Wimbledon
Emerson Jones in the third round in straight sets
The unseeded Brit caused another upset when she defeated third-seeded and home favorite Iva Jovic in the semi-final
Wakana Sonobe reached the third round at the Junior French Open
losing to eventual champion Tereza Valentova
the Japanese played knocked out the fourth-seeded Teodora Kostovic and the eighth-seeded Mingge Xu in the quarter-final and semi-final respectively
Stojsavljevic is in better form as she took out two of the top three seeds at the event
Your perspective matters!Start the conversation