There are no statistics available for this player Thanks for visiting The use of software that blocks ads hinders our ability to serve you the content you came here to enjoy We ask that you consider turning off your ad blocker so we can deliver you the best experience possible while you are here « Back Guardia Civil officers in Yaiza have arrested a couple who committed at least 17 burglaries and thefts in Playa Blanca. An investigation was mounted in nearly April after a sharp rise in burglaries from rooms while guests were absent. With the help of Yaiza Local Police’s Drone Unit, a woman was arrested with cell phones, money, cosmetics and perfumes. Although the other burglar had been identified, he remained at large committing thefts until he was detained by an off-duty police officer. Further evidence confirmed that the pair had fraudulently used stolen bank cards. The pair were later discovered to be one of the most active criminal pairs on Fuerteventura, accused of 20 crimes on the neighbouring island. Guardia agents from Fuerteventura came to Lanzarote to re-arrest the pair, who will face charges in Arrecife. Your email address will not be published. Required fields are marked * Save my name, email, and website in this browser for the next time I comment. Jet2 is expanding its winter 25/26 programme with more flights to 13 popular destinations (including Lanzarote & Fuerteventura) from Manchester Airport & London Stansted. Fire fighters were called to put out a minibus engine fire yesterday morning. Lanzarote Pool & Spa Shop in Playa Blanca are currently looking for an Office Administrator & Customer Service Representative. A head-on collision between two vehicles on the LZ-1 near Mala yesterday evening saw three people injured. Six local derbies will take place next season as three Lanzarote teams take part in Group 12 of the Third RFEF league. We are using cookies to give you the best experience on our website. You can find out more about which cookies we are using or switch them off in settings. Sign-up to the Gazette Newsletter to receive a weekly email including the most important news stories and upcoming events. This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful. Strictly necessary cookies should be enabled at all times so that we can save your preferences for cookie settings. If you disable this cookie, we will not be able to save your preferences. This means that every time you visit this website you will need to enable or disable cookies again. Union Sur Yaiza are almost certainly facing the drop as the season winds up. It’s a sad end to what has been a spirited campaign in the team’s historical first taste of the national leagues. Yaiza had already suffered two defeats on the trot before hosting Real Madrid “C”, and hopes of a great escape had already evaporated. But the Lanzarote side still showed spirit and resilience as they faced the Madrileños under the volcano. Union Sur Yaiza’s recent home defeat against Real Madrid’s second reserve team significantly diminishes the team’s chances of securing survival in the three remaining matches of the regular season of the Second Federation. Two goals from the visitors in the first half left the green and white team with no chance, and they were unable to get back into the game in the closing stages. Unión Sur Yaiza were able to deal with Real Madrid “C’s” initial push, as they pushed dangerously close to the area. Trovento tried to score after a pass from Marco Siverio, smashing the ball into a defender’s body, but later Carvajal made no mistake, putting the visitors ahead in the 15th minute. The Madrileños scored their second goal midway through the first half, with captain Carlos heading in a corner kick. Needing an audacious gamble to fight back, Yaiza’s coach Emilio Ferreras team made a double substitution in the 31st minute, bringing on Pablo Margallo and Nuha. It seemed to work at first – Unión Sur Yaiza stepped up to the challenge in the second half and almost reduced the deficit with a Pablo Bolado free kick, but the goal was denied as two home players caused an obstruction in the wall. A Nuha header that went wide and a Jordan cross that was cleared by the goalkeeper were the clearest chances. Although relegation from the league is not yet a mathematical certainty, the defeat leaves Unión Sur Yaiza on the brink of relegation. With three matches remaining at the time of writing, they are nine points behind Colonia Moscardó, the team occupying the play-off position. Consequently, even if the Greens win all three games their fate will still be in the hands of other sides. The last match of the season on 4th May will offer fans the chance to turn out and show appreciation to Yaiza and their first season at the highest level they have ever competed. FORTHCOMING HOME GAMES AT THE CAMPO DE FUTBÓL12 noon, Municipal Stadium of Yaiza (check beforehand) Of this very young dancer, it can be said, as a preliminary matter, that she was born and lives in the depths of a natural setting where the cante por soleá reached a unique brilliance. Yaiza Wheat saw its first light and grew up in the very caves of Alcalá de Guadaíra, that is, at the foot of the mythical castle where the three Marías climbed, as the lyrics tell. email and website in this browser for future purposes Privacy Policy Agreement * I agree to the terms and conditions of the Privacy Policy. The Voice of the Flamenco in the World.  Please enter your username or email address to reset your password 02 Feb 2025 12:00:00 GMT?.css-1txiau5-AnswerContainer{color:var(--GlobalColorScheme-Text-secondaryText2);}Getafe B won 1–0 over CD Union Sur Yaiza on Sun This is 21 of the Segunda Federacion - Group 5 Predicted lineups are available for the match a few days in advance while the actual lineup will be available about an hour ahead of the match The current head to head record for the teams are CD Union Sur Yaiza 0 win(s) Have scored 6 goals in their last 5 matches Who won between CD Union Sur Yaiza and Getafe B on Sun 02 Feb 2025 12:00:00 GMT?Getafe B won 1–0 over CD Union Sur Yaiza on Sun 02 Feb 2025 12:00:00 GMT.InsightsHave scored 5 goals in their last 5 matches CD Union Sur Yaiza is playing home against Getafe B on Sun Yaiza Martín has a very different life from a few years ago | en.edatv.news, Telecinco LIFESTYLE Impact on 'Fiesta': Yaiza Martín's New Life Is UnveiledThe Telecinco program has left everyone perplexed with the direction the Canary Islander has taken now30/03/2025 19:00:00h by María Merino Fiesta has left all its viewers perplexed this afternoon The reason is that it has uncovered the surprising new life of Yaiza Martín former contestant of Supervivientes and ex-girlfriend of Ginés Corregüela the Canary Islander disappeared from the public sphere and the program now wanted to uncover what she is doing she has left the sets to work in the motor world Yaiza Martín now works in the automotive sector | TelecincoFiesta Unveils the Transformation of Yaiza Martín Yaiza Martín burst onto the television scene as the defender and partner of Ginés Corregüela during his participation in Supervivientes especially when it was revealed that her relationship with him had begun while he was still married This caused family tensions and debates in various programs Yaiza has decided to step away from the media spotlight the program Fiesta has investigated her whereabouts and discovered that she has made a radical shift in her professional career driving a tow truck for a transport company from Monday to Friday she spends weekends repairing vehicles in a mechanical workshop This drastic change has surprised everyone considering her past in the entertainment world A reporter from Fiesta has traveled to the Canary Islands with the intention of interviewing Yaiza Martín and obtaining more details about her new life the former contestant has shown a reserved attitude A stance that contrasts notably with her previous willingness to share aspects of her personal and professional life on television Emma García has empathized with the Canary Islander and understood the reason for her silence: "It's because she suffered a lot." A stance that has also been supported by Juan Luis Galiacho and has provoked a reaction from Omar Suárez Emma García has understood what Yaiza Martín has done | TelecincoThis turn in Yaiza Martín's life reflects her ability to adapt and resilience Her return to motor-related work seems to be a return to her professional roots moving away from the media frenzy of recent years The audience of Fiesta has reacted with astonishment to this revelation evidencing the interest that the Canary Islander still generates Her decision to reinvent herself and seek a more discreet life is a reminder that public figures also seek their own path to happiness Bullock Lab Unión Sur Yaiza will return to the Third Federation next season after yesterday’s scoreless draw against Tenerife’s B team. The result confirmed relegation for the southern team, whose first season in the Second Federation began brightly but soon turned into a gruelling battle for survival, with exhausting fortnightly journeys to Madrid, rural Spain and even North Africa.   Yaiza will once again compete in Group 12 of the Third Federation, facing Canarian sides including local rivals San Bartolomé and, barring a miracle, UD Lanzarote. 06 Apr 2025 10:00:00 GMT?.css-1txiau5-AnswerContainer{color:var(--GlobalColorScheme-Text-secondaryText2);}AD Union Adarve won 1–0 over CD Union Sur Yaiza on Sun This is 30 of the Segunda Federacion - Group 5 The current head to head record for the teams are AD Union Adarve 1 win(s) Have scored 3 goals in their last 5 matches Who won between AD Union Adarve and CD Union Sur Yaiza on Sun 06 Apr 2025 10:00:00 GMT?AD Union Adarve won 1–0 over CD Union Sur Yaiza on Sun 06 Apr 2025 10:00:00 GMT.InsightsHave scored 1 goals in their last 5 matches AD Union Adarve is playing home against CD Union Sur Yaiza on Sun 09 Feb 2025 10:00:00 GMT?.css-1txiau5-AnswerContainer{color:var(--GlobalColorScheme-Text-secondaryText2);}CD Mostoles won 3–2 over CD Union Sur Yaiza on Sun This is 22 of the Segunda Federacion - Group 5 The current head to head record for the teams are CD Mostoles 0 win(s) Have scored 4 goals in their last 5 matches Who won between CD Mostoles and CD Union Sur Yaiza on Sun 09 Feb 2025 10:00:00 GMT?CD Mostoles won 3–2 over CD Union Sur Yaiza on Sun 09 Feb 2025 10:00:00 GMT.InsightsHave scored 5 goals in their last 5 matches CD Mostoles is playing home against CD Union Sur Yaiza on Sun has served on Yaiza’s council for 13 years His Unidos Por Yaiza party was re-elected with an absolute majority last year and he also serves as an opposition councillor in the Cabildo We spoke to him at Yaiza Ayuntamiento last month It’s been over a year since you were re-elected What are your main projects for this term of office We’d like to improve public transport adding two more lines to Playa Blanca’s internal service Security is another important factor for our visitors and we want to increase the police presence in Playa Blanca which reassure the public and also offer directions and advice We also want to improve the rubbish collections service and introduce the “fifth container” for organic waste we’d like to finally draw up and approve a General Plan for Yaiza Is there a date for the opening of the Playa Blanca sports centre yet but the company who won the contract to build it have continually asked for extensions and more money This ended up with a demand for a further €3 million We’re currently looking at the possibility of suing for breach of contract taking on management of the project ourselves or opening parts of the centre What about recent problems with sewage spills at the Town Beach and the bad smells issuing from the sewage treatment plant Playa Blanca is the fastest growing town on Lanzarote and its sewage system is old and almost obsolete and the pumps can’t always deal with all the waste the system is blocked by wet wipes and paper The Canarian Government have announced that they’ll extend and update the sewage works but the general issue is an island-wide problem Will cruisers be arriving at Playa Blanca next year That’s the request we made at international Cruise Fair at Miami this year We’d like to see Playa Blanca receiving medium-sized “boutique” cruisers and large yachts but it requires authorisation from the port authority It’s worth remembering that the harbour extension was not intended to convert Playa Blanca into a cruise port But we need to stay competitive now that other destinations such as Greece and Turkey are improving their offers What about the taxi queues in Playa Blanca in the evenings This is a problem we’re well aware of and we’re planning to grant ten new licences for taxi drivers There may be a lot of demand for taxis in the evenings but at other times of day there’s very little That means the taxi associations need to organise shifts and cars I’m also in favour of an islandwide taxi agreement It’s ridiculous that a taxi from San Bartolomé can bring tourists to Playa Blanca but is not allowed to pick up from here and must travel back empty Is there a project to widen the LZ-2 main road from Yaiza to Playa Blanca yet although it’s something I’m very much in favour of Objections to this sort of project often rely on the fact that new territory will be taken up by the road but in this case the territory is already there The problem that occurred when the smaller road was converted to a cycle route was that the slower heavy vehicles that previously used it went back onto the main road Nobody expected the coast road to El Golfo to collapse I would have liked to see immediate action but this is a National Park and highly protected The current Cabildo plan is to reinforce the existing road with pillars at a cost of €4 million El Golfo is an unmissable tourist attraction It seems as though the eternal complaints about lack of supermarkets in Playa Blanca may soon be solved we’re expecting Lidl to open in the industrial zone before Christmas and Aldi on the Femés road a few months later We also have Mercadona showing a lot of interest possibly in a site near the Marina Rubicón we’re also seeing professionals such as doctors and teachers turn down jobs because there’s nowhere to live and that mainly involves granting land and licences for construction There are parcels currently in preparation for social housing We also need to provide land for projects such as a new secondary school Local schoolchildren are tired of travelling to Mácher every day and website in this browser for the next time I comment Jet2 is expanding its winter 25/26 programme with more flights to 13 popular destinations (including Lanzarote & Fuerteventura) from Manchester Airport & London Stansted Fire fighters were called to put out a minibus engine fire yesterday morning Lanzarote Pool & Spa Shop in Playa Blanca are currently looking for an Office Administrator & Customer Service Representative A head-on collision between two vehicles on the LZ-1 near Mala yesterday evening saw three people injured Six local derbies will take place next season as three Lanzarote teams take part in Group 12 of the Third RFEF league We are using cookies to give you the best experience on our website You can find out more about which cookies we are using or switch them off in settings Sign-up to the Gazette Newsletter to receive a weekly email including the most important news stories and upcoming events This website uses cookies so that we can provide you with the best user experience possible Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful Strictly necessary cookies should be enabled at all times so that we can save your preferences for cookie settings we will not be able to save your preferences This means that every time you visit this website you will need to enable or disable cookies again Yaiza Ayuntamiento has announced a brand-new triathlon event “Magma Yaiza – Lanzarote Triatlón” 400 participants are expected to take part in the newest sporting event on Lanzarote’s calendar “Magma Yaiza – Lanzarote Triatlón” it has been announced by Yaiza Ayuntamiento unlike the 1,500 meters swimming of the Olympic modality the sprint is 20 kilometers and 5 kilometers of running while the Olympic distance is 40 kilometers on the bike and 10 kilometers of running a real challenge for the women and men registered” concluded by saying that “an event of this magnitude will also demonstrate our ability to organize and manage major activities thus increasing our credibility both at the island and regional level” Registration opens this Tuesday, February 18 on the web www.summitsportsevents.com Union Sur Yaiza’s players will face some long journeys in their first season in Spain’s national leagues after the Royal Spanish Football Federation decided the composition of the leagues in the Second Division RFEF Yaiza will play in Group V of the five-league division and their main objective will be to survive their first year at this level It is the first time a Lanzarote team has competed in the national leagues since UD Lanzarote were relegated from the Second Division B in 2010 The Yaiza team will swap short island hops and free Binter chocolate bars for the three-hour haul to Madrid for eight of their away games.  Four games will be played in Castilla La Mancha south of Madrid and two other fixtures will take place in Extremadura whose Badajóz Airport is not served directly by Lanzarote against CD Tenerife B and La Palma’s Atletico Paso.  will be to North Africa to play in the Spanish enclave of Melilla This will probably involve a flight to Andalusia and a ferry trip across the Straits of Gibraltar The season will begin on the weekend of the 31st August/ 1st September Yaiza Mayor Óscar Noda has claimed that cruise ships will be operating in Playa Blanca by this year or next Noda made the claim after a meeting with Canarian Mobility Minsiter Pablo Rodríguez saying “The councillor assures us that Promotur Turismo Canarias is already in charge of channelling the marketing strategy of our port for cruise tourism.” “the commitment that the minister conveys to us is that cruise ships will arrive in Playa Blanca A video uploaded to TikTok has caught the attention of residents on Lanzarote as it shows on of the island’s public buses almost crashing into a car while overtaking uploaded by user “playablancadigitall” shows a bus attempting to overtake on the LZ-2 near the Repsol petrol station The manoeuvre was a little too close for comfort as the bus and a car travelling in the opposite direction came quite close to each other the bus also almost forces a car off of the road forcing the driver to hit the brakes to avoid hitting the bus The Three Kings have already arrived on Lanzarote and are doing the rounds The biggest parade will take place in Arrecife this evening a parade will take place this morning in Puerto del Carmen’s old town while the Kings will swiftly pass through Costa Teguise at 12.35 Playa Blanca will host a full parade at 6 pm this evening is a national holiday in Spain and many shops and public buildings will be closed 11.30am: The Kings will arrive by boat at Puerto del Carmen’s harbour before parading from C/Teide to C/ Los Afrechos 6pm: Parade in Tías from roundabout at C/Perez Galdos/ Avenidad Central to Calle Libertad followed by letter collection at the football ground from Galeria de Yaiza to Plaza de los Remedios from roundabout near bus station to Plaza de Nuestra Señora de Carmen 5.30pm: Parade starts at football ground and ends at plaza de San Roque 6pm: The largest parade on the island will depart from Puerto Naos and head to the Parque Islas Canarias Yaiza’s Mayor Oscar Noda announced the latest developments in the saga of Playa Blanca’s sports centre yesterday Noda said that the works on the centre were 95% complete but had been paralysed due to the inability of the constructor Noda confirmed that the company had entered bankruptcy proceedings and stated that Yaiza had contracted assessors to advise on how to cancel the contract and complete the works itself Noda said that “we have always maintained our desire and commitment to finish the work and open the Pavilion We have reserved 700,000 euros from the municipal budget for its direct management to cover cleaning and we even have an advanced draft of the public prices for the use of the facility It is the fastest way to put the Pavilion into operation.” © 2025 EmCan Media - Hosted By canaryfone The Yaiza Council are taking steps to demolish the Son Bou hotel located in the main tourist area of Playa Blanca in response to long-standing legal pressures This action comes after a 2005 court order mandated the demolition of two-thirds of the hotel due to urban planning violations and excessive construction revealed that the Superior Court of Justice of the Canary Islands (TSJC) recently questioned the council as to why the demolition order has not been carried out The hotel’s license was revoked for violating planning laws and exceeding allowed construction limits Noda stated that due to the owner's inaction the council has now initiated the process to enforce the demolition order "We are moving forward because the property owner has ignored the situation The submitted plans do not meet the requirements and the responsibility falls on us," Noda explained He added that they have the execution project ready and will notify the property owner accordingly Noda highlighted that another hotel owned by the same people is also in a similar state of legal irregularity a demolition project was submitted to address the non-compliant areas but only a fraction of the work was completed Follow-up inspections confirmed that it still does not meet the required standards,” Noda said A report commissioned by the Yaiza Town Council has outlined the process for the partial demolition of the Son Bou Hotel in Playa Blanca The complex has been operating with twice the permitted number of guests and an excess of 6,000 square metres of built-up area beyond what was legally authorised the Son Bou Hotel in Playa Blanca appears to be just another tourist complex mirroring the typical holiday scene seen in surrounding buildings It lacks any identifying signage and has no reception Access is only possible via a ramp leading to a communal area or through an underground passage connecting it to the luxury hotel Princesa Yaiza and both have continued operating despite being classified as illegal The Son Bou hotel was originally granted planning permission in 1998 by former mayor Juan Francisco Reyes who is now serving a prison sentence for corruption Reyes pushed through over 1,500 tourist accommodation permits as part of a scheme to enrich himself while in office Court rulings from the Yate case determined that many of these licences were granted irregularly Reyes’ governance saw the rise of ‘developer-led urbanism’ where he demanded money from businesses with real estate interests in Yaiza under the pretext of expediting planning approvals he ignored essential legal requirements such as tourism permits and legal assessments Many of Yaiza’s current tourist complexes are legacies of this period Attempts at Legalisation and the Road to Demolition owner Juan Francisco Rosa has sought to legalise Son Bou His most recent attempt involved proposing an expansion of the neighbouring Princesa Yaiza hotel to integrate the Son Bou apartments the Yaiza Town Council commissioned a technical report to establish the necessary measures for the partial demolition of Son Bou to bring it in line with municipal urban planning regulations prepared by architect Maximiliano Valero Padilla found that the architectural plans submitted by the hotel’s owners did not correspond to the actual structure consists of three above-ground storeys and two underground levels The report confirmed that the Lanzarote Cabildo has revoked the original operating licence for the aparthotel the structure exceeds the permitted limits of the Yaiza General Planning Scheme The Son Bou hotel currently accommodates 220 guests double the 111 allowed under municipal regulations the total constructed area exceeds the legal limit by more than 6,000 square metres covering 9,427 square metres instead of the authorised 3,333 Demolition Proposal and Implementation Plan the technical report sets out how the partial demolition should be carried out to bring Son Bou in line with urban planning laws It also includes a series of renovation works for the parts of the building that will remain intact According to legal documents presented by the town council’s defence team the responsibility for preparing the demolition project lies with the hotel’s ownership which must comply with the findings of the technical report the property must ensure the physical execution of the demolition without further delays by hiring a construction firm with adequate resources A legal submission made to the Administrative Litigation Division of the Canary Islands High Court of Justice (TSJC) on 18th November 2024 granted the hotel 30 working days to accept the demolition proposal and six months to present a partial demolition plan the property will have 18 months to complete the works the Yaiza Town Council will take immediate action and carry out the demolition itself recovering the associated costs from the hotel’s ownership Demolition Scope and Structural Modifications The proposal does not require alterations to the second basement level but outlines significant changes to other floors the common area available to guests must be reduced to an 83-square-metre lounge To ensure that the basement level is not classified as a ground floor lowering the solarium area around the swimming pool the gym and changing rooms must be converted into internal service rooms The tunnel connecting Son Bou with the Princesa Yaiza Hotel will remain intact The most substantial changes begin on the ground floor where 76% of the vertical perimeter walls must be demolished to create an open-plan space All internal divisions and external fittings must also be removed The reception office and a service room will be transformed into guest communal areas and the entrance pergola will be dismantled a partial demolition of the vertical façade is required to comply with municipal regulations This floor must be transformed into an open-plan area The second floor will undergo the most extensive demolition with the complete removal of the building’s roof and flooring and sanitary facilities must be eliminated walkable rooftop fitted with the existing photovoltaic system the layout of the remaining apartments must be reconfigured to ensure that the hotel complies with the legal capacity of 111 guests The demolition of Son Bou marks a significant step in rectifying illegal developments in Lanzarote’s tourist sector the Yaiza Town Council aims to ensure compliance and restore adherence to urban planning laws in the region Metrics details Metastasis involves dissemination of cancer cells away from a primary tumour and colonization at distal sites the mechanical properties of the nucleus must be tuned since they pose a challenge to the negotiation of physical constraints imposed by the microenvironment and tissue structure We discovered increased expression of the inner nuclear membrane protein LAP1 in metastatic melanoma cells at the invasive front of human primary melanoma tumours and in metastases Human cells express two LAP1 isoforms (LAP1B and LAP1C) using in vitro and in vivo models that recapitulate human melanoma progression we found that expression of the shorter isoform constrained migration and invasion by allowing a weaker coupling between the nuclear envelope and the nuclear lamina We propose that LAP1 renders the nucleus highly adaptable and contributes to melanoma aggressiveness whether NE blebs contribute to cellular migratory programmes is unclear The involvement of nucleo-cytoskeletal connections in NE bleb dynamics suggests that studying how these structures are regulated might shed light into how tumour cells withstand high-level mechanical stress we challenged melanoma cells derived from primary tumours and those derived from isogenic metastatic lesions to multiple migratory constraints and 3D invasion in collagen to identify proteins that enable cells to negotiate these challenges molecular cell biology and advanced microscopy we discovered that elevated expression of the inner nuclear membrane (INM) protein lamin-associated polypeptide 1 (LAP1) supports the ability of metastatic cells to overcome repetitive physical challenges through a migratory programme involving NE blebbing cells were challenged to migrate through transwells once or collected after a round of migration and challenged again The arrows indicate the direction for chemotactic migration Percentage of primary melanoma WM983A cells and metastatic melanoma WM983B cells stably expressing GFP-NLS that translocated their nuclei (b) and displayed NE blebs (c) after one round of migration in transwells of various pore sizes Percentage of WM983A and WM983B cells stably expressing GFP-NLS that translocated their nuclei (d) and displayed NE blebs (e) after a second round of transwell migration through 5 μm pores Representative images of WM983A and WM983B cells stably expressing GFP-NLS and stained for DNA after a second round of transwell migration through 5 μm pores Transwell pores were visualized using transmitted light Magnifications show nuclei that translocated and displayed NE blebs indicated by white arrowheads Percentage of WM983A and WM983B cells stably expressing GFP-NLS that translocated their nuclei (g) and displayed NE blebs (h) after one round of transwell migration through 8 μm pores upon ROCK inhibitor (ROCKi Percentage of WM983A and WM983B cells stably expressing GFP-NLS that translocated their nuclei (i) and displayed NE blebs (j) after a second round of transwell migration through 5 μm pores upon ROCKi treatment Resolved lysates from WM983A and WM983B cells grown in 2D or collected after overnight passage through 8 μm transwell pores were examined by western blotting with anti-pMLC and anti-GAPDH anti-sera Bar charts show the mean and error bars represent s.e.m error bars represent the standard deviation (s.d.) from N = 4 independent experiments P values calculated by one-way ANOVA (g–k) two-way ANOVA (b and c) and two-tailed unpaired t-test (d and e); *P < 0.05 Numerical data and exact P values are available in source data Source data suggesting that passage through the first constraint activates a Rho-ROCK1/2-dependent migration programme specifically in metastatic melanoma cells Percentage of primary melanoma WM983A and metastatic melanoma WM983B cells grown in 2D displaying NE blebs Representative images of WM983B nuclei with NE blebs of different shapes stained for Lamin A/C (magenta) and DNA (blue) Percentage of nuclei with NE blebs according to bleb number per nucleus and bleb shape in WM983A and WM983B cells Percentage of NE blebs containing Lamin A/C Lamin B1 or Lamin B2 in WM983A and WM983B cells Representative images of a WM983B nucleus with an NE bleb stained for Lamin A/C (green) Representative live-cell image sequence of WM983B GFP-NLS nuclei with an intact NE bleb (left) and a ruptured NE bleb (right) with correlative serial block-face scanning electron microscopy (SBF-SEM) images of the same nuclei The white arrow indicates the site of rupture of the nuclear membranes Percentage of intact and ruptured NE blebs in WM983A and WM983B cells imaged over the course of 15 h Percentage of intact and ruptured NE blebs in WM983A (n = 486 and 522 cells respectively) and WM983B (n = 453 and 560 cells respectively) cells stably expressing GFP-NLS after treatment with GSK269962A and imaged over the course of 15 h Duration of NE rupture in WM983A and WM983B cells stably expressing GFP-NLS and imaged live (not significant (NS) NE rupture events per hour in WM983A and WM983B stably expressing GFP-NLS and imaged live bar charts show the mean and error bars represent s.e.m horizontal lines show the median and whiskers show minimum and maximum range of values g and h) and two-tailed unpaired t-test (a Source data These results suggest that metastatic melanoma cells have a higher background level of NE instability Fold regulation of candidate genes expression validated by RT–qPCR in A375M2 compared with A375P TOR1AIP1 and SUMO1 expression validated by RT–qPCR in metastatic melanoma WM983B cells compared with primary melanoma WM983A cells Heat maps displaying fold change in expression of candidate genes in melanoma cell lines compared with melanocytes from Philadelphia and Mannheim datasets TOR1AIP1 expression in primary tumours and metastasis in Kabbarah (n = 31 and 73 Experimental data have been pooled from three individual experiments P values calculated by two-tailed unpaired t-test (a–d); *P < 0.05 Source data These data suggest that expression of TOR1AIP1 is upregulated during melanoma progression Schematic of TOR1AIP1 human gene transcription and translation The gene comprises ten exons and encodes a long protein isoform (584 amino acids) and a short protein isoform (462 amino acids) resulting from the use of an alternative translation initiation site at position 122 Representative immunoblot of LAP1 expression levels in the indicated melanocytes primary melanoma cells and metastatic melanoma cells Quantification of LAP1B and LAP1C protein expression in panel of cell lines in b Representative immunoblot of LAP1 expression levels in WM983B cells upon transfection with pooled LAP1-targeting siRNA Percentage of WM983B cells that translocated their nuclei (e) and displayed NE blebs (f) after a second round of transwell migration through 5 μm pores upon LAP1 depletion with siRNA pool 3D invasion index (number of invading cells at 50 μm/total number of cells) of WM983B cells in 3D collagen I matrices upon LAP1 depletion with siRNA pool Representative images of WM983B cells stained for DNA at 0 μm and 50 μm into collagen upon LAP1 depletion with siRNA pool P values calculated by two-tailed unpaired t-test (e–g); **P < 0.01 numerical data and exact P values are available in source data Source data LAP1 allows metastatic melanoma cells to negotiate migratory constraints in the microenvironment We suggest that LAP1C can move more freely in the INM than LAP1B and can populate NE blebs in a Lamin A/C-dependent manner Percentage of primary melanoma WM983A cells stably expressing GFP-NLS alone or WM983A cells stably expressing GFP-NLS and LAP1C-mRuby3 LAP1B-mRuby3 or LAP1-mRuby3 and metastatic melanoma WM983B cells stably expressing GFP-NLS that translocated their nuclei (a) and displayed NE blebs (b) after a second round of transwell migration through 5 μm pores WM983A GFP-NLS LAP1B-mRuby3 or WM983A GFP-NLS LAP1C-mRuby3 cells invading into collagen I matrices and stained for DNA at Z = 0 μm and Z = 50 μm (c) and 3D invasion index from c (d) Schematic of LAP1B lacking the arginine finger (LAP1BR563G) LAP1B lacking lamin-binding region 1–72 (LAP1BΔ1-72) LAP1B lacking its chromatin-binding region (LAP1BΔCBR) and LAP1C and LBR-fusions to LAP1C’s N-terminus Percentage of WM983A cells stably expressing GFP-NLS and LAP1B-mRuby3 LAP1BΔCBR-mRuby3 or LAP1BR563G-mRuby3 that translocated their nuclei (f) and displayed NE blebs (g) after a second round of transwell migration through 5 μm pores Representative images of WM983A GFP-NLS LAP1B-mRuby3 WM983A GFP-NLS LAP1BΔCBR-mRuby3 and WM983A GFP-NLS LAP1BR563G-mRuby3 cells invading into collagen I matrices and stained for DNA at Z = 0 μm and Z = 50 μm into collagen (h) and 3D invasion index for h (i) Percentage of primary melanoma WM983A cells stably expressing GFP-NLS and LAP1C-mRuby3 LBRNT-LAP1C-mRuby3 or LBRTRS-LAP1C-mRuby3 that translocated their nuclei (j) and displayed NE blebs (k) after a second round of transwell migration through 5 μm pores Representative images of WM983A GFP-NLS LAP1C-mRuby3 WM983A GFP-NLS LBRNT-LAP1C-mRuby3 and WM983A GFP-NLS LBRTRS-LAP1C-mRuby3 cells invading into collagen I matrices and stained for DNA at Z = 0 μm and Z = 50 μm into collagen (l) and 3D invasion index for l (m) P values calculated by one-way ANOVA; *P < 0.05 Source data We suggest that the strong NE/lamina tethering provided by LAP1B and its activation of Torsin-1A do not allow NE blebbing and constrained migration whereas the weaker NE/lamina tethering provided by LAP1C allows NE blebbing and lets cells negotiate physical constraints Representative images and QuPath mark-up (map) of haematoxylin and eosin (HE) staining (a) and quantification of invading cells into the dermis (b) from day 42 WM983A and WM983B tumours grown in NXG mice Dashed lines represent the boundary between PIF and DIF HE-positive tumour cells are in red in the map Representative images and QuPath mark-up of HE staining (c) and quantification of invading cells into the dermis (d) from day 24 and day 36 A375P tumours and day 24 A375M2 tumours grown in NXG mice (d) Representative images (e) and percentage of tumour cell nuclei according to LAP1 intensity score in TB PIF and DIF (f) of day 42 WM983A and WM983B tumours Representative images (g) and percentage of tumour cell nuclei according to LAP1 intensity score in TB PIF and DIF (h) of day 24 and day 36 A375P tumours and day 24 A375M2 tumours i–k Representative and QuPath mark-up of HE staining (i) quantification of invading cells into the dermis (j) and tumour growth curves (k) of A375P GFP-NLS LAP1B-mRuby3 A375P GFP-NLS LAP1C-mRuby3 and A375M2 GFP-NLS tumours grown intradermally in NXG mice graphs show the mean and error bars represent s.d P values calculated by one-way ANOVA (d and j) two-way ANOVA (f and h) and two-tailed unpaired t-test (b) significant P values shown are for LAP1 score 3 Source data suggesting that these cancer cells establish different interactions with the tumour microenvironment for their differential growth in vivo our data show that LAP1C supports tumour invasion both in vitro and in vivo Representative images of TB and IF of a primary tumour and a metastasis in human melanoma patient cohort A The magnifications show representative cell nuclei H-score for LAP1 staining in TB and IF of primary tumours and metastases in cohort A by unpaired (left) or paired (right) analysis Percentage of tumour cell nuclei according to LAP1 intensity score in TB and IF of primary tumours and metastases in patient cohort A Significant P values shown are for LAP1 score 3 Representative images of TB and IF of a primary tumour and a metastasis in human melanoma patient cohort B H-score for LAP1 staining in TB and IF of primary tumours and metastases in patient cohort B by unpaired (left) or paired (right) analysis Percentage of tumour cell nuclei according to LAP1 intensity score in TB and IF of primary tumours and metastases in patient cohort B Kaplan–Meier survival curve of disease-free survival according to LAP1 expression in the IF from primary melanomas LAP1 expression was categorized as low or high using the mean expression LAP1 levels are elevated at the IF of melanoma tumours which are enriched in cells displaying amoeboid features like a rounded cell morphology can localize to NE blebs in a Lamin-A/C-dependent manner and promotes transit through physical constraints through its weaker N-terminal NE/lamina tethering allowing NE blebbing P values calculated by one-way ANOVA (b and e) two-tailed unpaired and paired t-test (b and e) and log-rank test (g); *P < 0.05 Source data Here we identify the INM protein LAP1 as a master regulator of NE remodelling during melanoma progression we propose that by fine tuning expression and localization of LAP1 isoforms at the NE cells may alter their array of nucleo-cytoskeletal connections and Torsin activation to modulate nuclear plasticity and allow their negotiation of physical constraints We found that LAP1 could be a prognostic marker in human melanoma and propose that a better understanding of LAP1 function would not only provide a route to prevent metastatic dissemination but also may guide research on normal or pathological cell states featured by perturbed nuclear membranes This research complies with all relevant ethical regulations; all animals were maintained under specific-pathogen-free conditions and handled in accordance with the Institutional Committees on Animal Welfare of the UK Home Office (The Home Office Animals Scientific Procedures Act All animal experiments were approved by the Ethical Review Process Committees at Barts Cancer Institute or King’s College London and carried out under license from the Home Office tumour samples were processed by IRB Lleida (PT17/0015/0027) and HUB-ICO-IDIBELL (PT17/0015/0024) Biobanks integrated in the Spanish National Biobank Network and Xarxa de Bancs de Tumors de Catalunya following standard operating procedures with approval of their ethics and scientific committee and were collected with specific informed consent in accordance with the Helsinki Declaration WM1361 and WM793B were cultured in Roswell Park Memorial Institute medium (Gibco) supplemented with 10% foetal bovine serum (FBS) and 1% (v/v) penicillin and streptomycin (PenStrep A375P and A375M2 were cultured in Dulbecco’s modified Eagle’s medium (DMEM Gibco) supplemented with 10% FBS and 1% (v/v) PenStrep; M206 and M443 were cultured in MBM-4 basal growth medium (Lonza) supplemented with the Melanocyte Growth Medium-4 BulletKit (MGM-4 Lonza) supplemented with 1% (v/v) PenStrep Cells were grown at 37 °C and 5% or 10% CO2 Cells were kept in culture to a maximum of three or four passages CAL-51 or WM983B cells were seeded at a density of 8 × 104 cells in 4-well or 24-well plates and transfected with 0.5 μg of vector using Lipofectamine 3000 (Invitrogen) CAL-51 cells were fixed with 4% formaldehyde (FA) for 15 min at room temperature HEK293T cells were seeded at a density of 4 × 105 cells ml−1 in six-well plates cells were transfected with 1.5 μg of lentiviral vector 0.5 μg of pVSVG and 2 μg of HIV-1 pCMVd8.91 using Lipofectamine 3000 cells were transfected with 1.5 μg of retroviral vector 0.5 μg of pHIT-VSVG and 2 μg of MLV-GagPol using Lipofectamine 3000 Viral supernatants were collected 48 h post-transfection filtered (0.2 μm) and used to transduce melanoma cells Antibiotic selection as required was started 48 h post-infection Transwell migration and invasion assays were carried out 48 h post-transfection Cells were starved in serum-free DMEM overnight and seeded at a density of 1.65 × 105 cells ml−1 per insert in 24-well plates or 2.335 × 106 cells ml−1 per insert in 6-well plates Cells were allowed to migrate 16 h in 24-well plates and 24 h in 6-well plates cells were collected after one round (24 h) from inserts in 6-well plates and seeded on inserts in 24-well plates Cells were fixed with 4% FA for 15 min at room temperature ROCKi GSK269962A (Axon MedChem) was used at 1 μM and staurosporin (Cell Guidance Systems) was used at 1 μM the inhibitor was added to the chemoattractant Melanoma cells were seeded at a density of 1 × 105 cells ml−1 in 12-well plates 24 h before the experiment RNA was extracted using TRIzol (Life Technologies) following the manufacturer’s instructions RNA was treated with DNA-free DNA Removal Kit (Life Technologies) and RNA purity was determined with an ND-1000 Nanodrop (Thermo Fisher Scientific) QuantiTect primer assays and Brilliant III SYBR Green QRT-PCR Kit (Agilent Technologies) in a ViiA 7 Real-Time PCR System (Thermo Fisher Scientific) The following qPCR primers from Qiagen were used: RANBP2 (QT00035378) ZMPSTE24 (QT00025627) and TOR1AIP1 (QT00070147) Melanoma cells were seeded at a density of 6 × 105 cells ml−1 in 12-well plates and lysed the next day with LDS buffer 1× (Life Technologies) Lysates were denatured at 95 °C for 5 min and sonicated SDS–PAGE and western blotting were performed using standard procedures Membranes were visualized and bands quantified using an Odyssey Fc (LI-COR) Loading controls were run on the same blot Individual 680 and 800 channels were co-visualized in greyscale on the same image Primary antibodies were: LAP1 (1:1,000; #21459-1-AP) #10895-1-AP) from Proteintech; pThr18/Ser19-MLC2 (1:750 #3672) from Cell Signaling Technology; GAPDH (1:10,000 Secondary antibodies were: IRDye 680RD goat anti-rabbit IgG (1:10,000 #925-68071) and IRDye 800RD goat anti-mouse IgG (1:10,000 The assays performed were adapted from ref. 44 Protein solubilization from melanoma cell lysates was carried out using the following extraction buffers supplemented with 1 mM dithiothreitol 0.3 mM phenylmethylsulfonyl fluoride and cOmplete EDTA-free protease inhibitor tablet (Roche): 50 mM Tris–HCl pH 7.5 (hypotonic); 50 mM Tris–HCl pH 7.5 1% Triton-X-100 (hypotonic + detergent); 100 mM Tris–HCl pH 7.5 1% Triton-X-100 (low salt + detergent); 500 mM Tris–HCl pH 7.5 Protein lysates were incubated for 20 minutes on ice and then centrifuged at 14,000g for 15 min The supernatants were combined with 4× LDS buffer and the pellets solubilized with 1× LDS buffer Collagen I matrices were prepared using FibriCol (CellSystems) at 1.7 mg ml−1 and melanoma cells were seeded on top at a density of 5 × 103 in 96-well plates Medium was changed the next day to DMEM 1% FBS cells were fixed with 20% FA for 15 min at room temperature cells were fixed with 2% FA for 30 min at room temperature Collagen I was prepared using FibriCol at 2.3 mg ml−1 Melanoma cells were suspended in serum-free DMEM to a final concentration of 1.5 × 104 cells per 100 μl of collagen Cells were centrifuged at 1,800 rpm and 4 °C for 8 min resuspended in collagen and seeded on glass-bottom 96-well plates (Ibidi) Plates were centrifuged at 900 rpm for 5 min to get all the cells at the bottom Cells in collagen were fixed with 20% FA overnight at 4 °C The 3D invasion index was obtained by dividing the number of invading cells at 50 μm by the total number of cells Cells in coverslips were fixed with 4% FA for 15 min at RT permeabilized with 0.3%Triton-X-100 for 20 min blocked with 4% bovine serum albumin (BSA) for 30 min and incubated sequentially with primary antibody in 4% BSA for 2 h at room temperature and secondary antibody in 4% BSA for 1 h at room temperature DNA was stained with DAPI 1:1,000 or Hoechst 1:5,000 in PBS (Gibco) cells were washed in PBS pre-fixation and incubated with CSK buffer (10 mM PIPES 5 mM Na2VO3 and 0.5% Triton-X-100) for 3 min and again for 1 min on ice Cells were fixed with 4% FA for 20 min on ice blocked with 10% goat serum for 1 h at room temperature and incubated sequentially with primary antibody in 1% goat serum overnight at 4 °C and with secondary antibody in 1% goat serum for 1 h at room temperature cells were permeabilized with 0.5% Triton-X-100 for 30 min incubated with primary antibody in 4% BSA overnight at 4 °C and with secondary antibody in 4% BSA for 2 h at room temperature #10298-1-AP) from Proteintech or (1:200; #mab3538) from Millipore; Lamin B1 (1:200 LAP1 (1:200; #21459-1-AP) and Emerin (1:1,000 #10351-1-AP) from Proteintech; pSer19-MLC2 (1:200 #901503) from BioLegend; Gamma-H2AX (1:600 #NB100305) from Novus Biologicals; Mab414 (1:200 Secondary antibodies were Alexa Fluor 488 and Alexa Fluor 555 (1:1,000) from Life Technologies and raised in donkeys against the corresponding species F-actin was stained using Alexa Fluor 546-phalloidin from Life Technologies and DNA with Hoechst 33342 from Invitrogen Images were acquired with a Dragonfly 200 high-speed spinning disc confocal microscope (Andor) Imaging was carried out with 20× dry or 60× oil objectives Z-stacks of 1–5 μm step-size distance were acquired from fixed cells in 2D A Z-range of 50 μm was used to assess 3D invasion into collagen I Live cell imaging was performed at 37 °C and 5% CO2 in an environmental chamber Movies were taken at 2 min intervals for 1–15 h Image analysis was carried out using ImageJ Fluorescence signal intensities were quantified from pixel intensity in single cells relative to the areas of interest Cells were seeded at a density of 8 × 104 in four-well chamber slides (Ibidi) 24 h before the experiment An LSM 880 Carl Zeiss microscope was used for imaging Cells were kept at 37 °C and 5% CO2 in a sealed chamber Cells were imaged with a 63×/1.4 NA objective five pre-bleached values were acquired and then squares of 1.3 × 1.3 (1.69 μm2) at the main NE and at NE blebs were bleached with 50% laser intensity Fluorescence recovery was measured every second for 200 cycles The FRAP data were curated subtracting background and normalized Permutations were set to 1,000 and permutation type to gene-set Gene Ontology gene sets were classified according to Gene Ontology ontologies Upregulated gene sets were filtered on the basis of FDR <5% and P < 0.05 no statistical method was used to pre-determine sample size the experiments were not randomized and the investigators were not blinded to allocation during experiments or outcome assessment Further information on research design is available in the Nature Portfolio Reporting Summary linked to this article All other data supporting the findings of this study are available from the corresponding authors on reasonable request Biological materials created in this study can be obtained from the corresponding authors on reasonable request No code beyond freely available ImageJ tools was used in this study Pre-clinical modeling of cutaneous melanoma TGF-β-induced transcription sustains amoeboid melanoma migration and dissemination Regional activation of myosin II in cancer cells drives tumor progression via a secretory cross-talk with the immune microenvironment Myosin II reactivation and cytoskeletal remodeling as a hallmark and a vulnerability in melanoma therapy resistance Diverse matrix metalloproteinase functions regulate cancer amoeboid migration WNT11-FZD7-DAAM1 signalling supports tumour initiating abilities and melanoma amoeboid invasion ROCK and JAK1 signaling cooperate to control actomyosin contractility in tumor cells and stroma Rac activation and inactivation control plasticity of tumor cell movement Cell jamming: collective invasion of mesenchymal tumor cells imposed by tissue confinement Intravital third harmonic generation microscopy of collective melanoma cell invasion: principles of interface guidance and microvesicle dynamics Physical limits of cell migration: control by ECM space and nuclear deformation and tuning by proteolysis and traction force Nuclear deformability constitutes a rate-limiting step during cell migration in 3-D environments Mechanics and functional consequences of nuclear deformations The distinct roles of the nucleus and nucleus–cytoskeleton connections in three-dimensional cell migration Emerging views of the nucleus as a cellular mechanosensor Repetitive disruptions of the nuclear envelope invoke temporary loss of cellular compartmentalization in laminopathies Transient nuclear envelope rupturing during interphase in human cancer cells Perinuclear Arp2/3-driven actin polymerization enables nuclear deformation to facilitate cell migration through complex environments Fine control of nuclear confinement identifies a threshold deformation leading to lamina rupture and induction of specific genes Actomyosin drives cancer cell nuclear dysmorphia and threatens genome stability ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death Nuclear envelope rupture and repair during cancer cell migration Nuclear envelope rupture is induced by actin-based nucleus confinement DNA damage follows repair factor depletion and portends genome variation in cancer cells after pore migration Compromised nuclear envelope integrity drives TREX1-dependent DNA damage and tumor cell invasion Rupture dynamics and chromatin herniation in deformed nuclei Blebs lead the way: how to migrate without lamellipodia Confinement hinders motility by inducing RhoA-mediated nuclear influx Nesprin-2 accumulates at the front of the nucleus during confined cell migration Modes of invasion during tumour dissemination Quantitative phase imaging unravels new insight into dynamics of mesenchymal and amoeboid cancer cell invasion Cortical contractility triggers a stochastic switch to fast amoeboid cell motility Confinement and low adhesion induce fast amoeboid migration of slow mesenchymal cells The role and regulation of blebs in cell migration Genomic analysis of metastasis reveals an essential role for RhoC Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature Integrative genome comparison of primary and metastatic melanomas The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastases Identification of a novel human LAP1 isoform that is regulated by protein phosphorylation Molecular cloning of one isotype of human lamina-associated polypeptide 1s and a topological analysis using its deletion mutants Integral membrane proteins of the nuclear envelope interact with lamins and chromosomes and binding is modulated by mitotic phosphorylation Integral membrane proteins specific to the inner nuclear membrane and associated with the nuclear lamina Torsin ATPases influence chromatin interaction of the Torsin regulator LAP1 In vivo identification of GTPase interactors by mitochondrial relocalization and proximity biotinylation How lamina-associated polypeptide 1 (LAP1) activates Torsin Regulation of Torsin ATPases by LAP1 and LULL1 The nucleus measures shape changes for cellular proprioception to control dynamic cell behavior The nucleus acts as a ruler tailoring cell responses to spatial constraints Parallels between cytokinesis and retroviral budding: a role for the ESCRT machinery A combined approach for the localization and tandem affinity purification of protein complexes from metazoans Loss of pigment epithelium-derived factor enables migration invasion and metastatic spread of human melanoma Comprehensive expression profiling of tumor cell lines identifies molecular signatures of melanoma progression Transcriptional profiles in melanocytes from clinically unaffected skin distinguish the neoplastic growth pattern in patients with melanoma Download references is a Wellcome Trust Senior Research Fellow (206346/Z/17/Z) is a Cancer Research UK (CRUK) Senior fellow and the V.S.-M lab was supported by (CRUK) C33043/A24478 and Barts Charity lab by a Fundación Alfonso Martin Escudero fellowship and Marie Skłodowska-Curie Action received a King’s Health Partners PhD studentship R.M.M was funded by ISCIII/FEDER ‘Una manera de hacer Europa’ FIS-PI1500711 and PI18/00573; R.M.M and X.M.-G were funded by CIBERONC CB16/12/0023 UK) for their supervision with cell biology experiments Marais (Cancer Research UK Manchester Institute) for the melanoma cells provided and B Jiménez (Universidad Autónoma de Madrid and Instituto de Investigaciones Biomédicas CSIC-UAM Marshall (Queen Mary University of London) for help with animal experiments This work was supported in part by the Francis Crick Institute which receives its core funding from Cancer Research UK (FC001002 and FC001999) the UK Medical Research Council (FC001002 and FC001999) and the Wellcome Trust (FC001002 and FC001999) the author has applied a CC BY public copyright licence to any Author Accepted Manuscript version arising from this submission These authors contributed equally: Victoria Sanz-Moreno These authors jointly supervised this work: Victoria Sanz-Moreno Irene Rodriguez-Hernandez & Victoria Sanz-Moreno School of Cancer and Pharmaceutical Sciences Randall Division of Cell and Molecular Biophysics Electron Microscopy Science Technology Platform Advanced Light Microscopy Science Technology Platform Department of Pathology and Molecular Genetics supervised experiments and wrote the paper; Y.J.-G analysed the data and wrote the paper; O.M performed immunohistochemistry and digital pathology and supervised mouse work; I.R.-H assisted with the transcriptomic analyses and qPCR; J.M performed and supervised the CLEM experiments; M.J.R in FRAP and supervised the experiments; R.M.M The authors declare no competing interests Nature Cell Biology thanks Matthieu Piel, and the other, anonymous, reviewer(s) for their contribution to the peer review of this work. Peer reviewer reports are available Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations b) Percentage of primary melanoma WM983A and metastatic melanoma WM983B cells that did not translocate their nuclei (a) and displayed nuclear envelope blebs (b) after one round of migration in transwells of various pore sizes (c,d) Percentage of WM983A and WM983B cells that translocated their nuclei and displayed nuclear envelope blebs classified according to bleb number (c) and bleb shape (d) after one round of migration in transwells of various pore sizes (e,f) Percentage of WM983A and WM983B cells that did not translocate their nuclei (e) and displayed nuclear envelope blebs (f) after a second round of transwell migration through 5-μm pores (g) Percentage of WM983A and WM983B cells that translocated their nuclei and displayed nuclear envelope blebs classified according to bleb number (left) and bleb shape (right) after a second round of transwell migration through 5-μm pores (h,i) Percentage of WM983A and WM983B cells that translocated their nuclei (h) and displayed nuclear envelope blebs (i) after a third round of transwell migration through 5-μm pores Bar charts show the mean and error bars represent S.E.M P-values calculated by two-way ANOVA (a,b,c,d,g) and unpaired two-tailed t-test (e,f,h,i); *p < 0.05 Numerical data and exact p-values are available in the Source Data Source data (a) Percentage of alive primary melanoma WM983A cells and metastatic melanoma WM983B cells after a first round of migration in transwells through 8-μm pores (b) Percentage of alive WM983A and WM983B cells after a second round of migration in transwells through 5-μm pores upon staurosporin treatment (c) Representative pictures of WM983A and WM983B cells expressing GFP-NLS (green) and stained for caspase-3 (magenta) and DNA (blue) after a second round of migration in transwells through 5-μm pores in the presence or absence of staurosporin (d) Resolved cell lysates of WM983A and WM983B cells after treatment with ROCK inhibitor (ROCKi) GSK269962A were examined by western blotting with antisera raised against GAPDH (e) Representative pictures of WM983A and WM983B cells treated with ROCKi and stained for pMLC2 (magenta) lamin A/C (green) and DNA (blue) after a first round of transwell migration through 8-μm pores (f,g) Percentage of WM983B cells that translocated their nuclei (f) and displayed nuclear envelope blebs (g) after a second round of transwell migration through 8-μm pores upon ROCK inhibitor (ROCKi) GSK269962A treatment Bar charts show means and error bars represent S.E.M P-values calculated by unpaired two-tailed t-test (a,f,g) numerical data and exact p-values are available in the Source Data Source data (a) Percentage of nuclei with nuclear envelope blebs in M206 melanocytes (b) Representative image of M206 melanocytes stained for lamin A/C (magenta) and DNA (blue) The magnification shows a M206 nucleus with a nuclear envelope bleb percentage of elongated and rounded cells (d) and pMLC2 levels (e) in primary melanoma WM983A cells and metastatic melanoma WM983B cells grown on collagen I percentage of elongated and rounded cells (g) and pMLC2 levels (h) in less metastatic melanoma A375P cells and highly metastatic melanoma A375M2 cells grown on collagen I A375P and A375M2 cells stained for pMLC2 (green) actin (magenta) and DNA (blue) on collagen I The magnifications show representative cells and in the magnification the scale bars are 10 μm (j) Percentage of nuclei with nuclear envelope blebs in WM983A and WM983B cells grown on collagen I (k) Percentage of nuclei with nuclear envelope blebs in A375P and A375M2 cells grown on collagen I A375P and A375M2 cells stained for lamin A/C (green) In a,d,g,j,k Bar charts show the mean and error bars represent SEM from N = 3 independent experiments In c,e,f,h horizontal lines show the median and whiskers show minimum and maximum range of values p values calculated by two-way ANOVA (d,g) and unpaired two-tailed t-test (c,e,f,h,j,k); **p < 0.01 Source data (a) Percentage of nuclear envelope blebs positive for DNA damage response markers (53BP1 and γ-H2AX) in primary melanoma WM983A cells and metastatic melanoma WM983B cells (b) Representative pictures of a WM983B nucleus stained for γ-H2AX (green) (c) Relative γ-H2AX and 53BP1 fluorescence intensity levels (left) and average γ-H2AX and 53BP1 foci per nucleus (right) in WM983A and WM983B cells with or without nuclear envelope blebs (d,e) Representative image sequence from repetitive transient nuclear envelope rupture events in WM983A cells (d) or WM983B cells (e) stably expressing GFP-NLS and imaged over 5 hours Images showing the first frame of a nuclear envelope rupture in (d) or (e) are surrounded by a magenta square Numerical data are available in the Source Data Source data (a) Flow diagram of GSEA carried out comparing highly amoeboid and highly metastatic melanoma A375M2 cells with less amoeboid and less metastatic melanoma A375P cells from data of gene expression microarray analysis (b) The upper pie charts show the distribution of upregulated and downregulated nuclear gene sets in A375M2 cells (left) and A375P cells (right) The lower pie chart shows the 12 most enriched GO gene set categories in A375M2 (c) Section of heatmap of the leading-edge analysis showing a cluster of upregulated nuclear envelope genes in A375M2 cells (d) Flow diagram of the GSEA carried out comparing A375M2 cells with A375M2 cells treated with contractility inhibitors (ROCK inhibitors H1152 or Y27632 or myosin inhibitor blebbistatin) (A375M2_inh) The graphs show the distribution of upregulated and downregulated nuclear gene sets in A375M2 cells (left) and A375M2_inh (right) (e) Upregulated nuclear envelope genes selected from leading-edge analysis with their log2 fold change in expression and statistical significance in A375M2 compared to A375P cells and in A375M2 compared to A375M2_inh Statistically significant upregulated genes appear in bold in the table P-values calculated by two-tailed unpaired t-test Source data (a) Quantification of LAP1B (left) and LAP1C (right) expression in metastatic melanoma WM983B cells after 48 hours of treatment with a siGENOME SMARTpool targeting LAP1 (b) Percentage of alive WM983B cells after a first round of transwell migration upon LAP1 depletion with a siGENOME SMARTpool (c) Representative immunoblot for LAP1 expression levels in WM983B cells after 48 hours of LAP1 depletion with ON-TARGETplus individual siRNAs Western blot was probed with anti-GAPDH and anti-LAP1 antisera (d) Quantification of LAP1B (left) and LAP1C (right) expression in WM983B cells after 48 hours of LAP1 depletion with ON-TARGETplus individual siRNAs as in (c) (e,f) Percentage of WM983B cells that translocated their nuclei (e) and displayed nuclear envelope blebs (f) after a second round of transwell migration through 5-μm pores upon LAP1 depletion with ON-TARGETplus individual siRNAs P-values calculated by one-way ANOVA (d,e,f) and unpaired two-tailed t-test (a,b); *p < 0.05 Source data (a) Resolved soluble (S) and insoluble (P) fractions from WM983B cells subject to the indicated extractions were examined by western blotting with antisera raised against LAP1 Western blot representative of N = 2 independent experiments (b) Schematic of the different N-terminal domains of LAP1 isoforms and cartoon illustrating the mitochondrial retargeting assay (c) Representative images of mitochondrial retargeting assay in cells expressing mEmerald-Lamin A/C (left) or mEmerald-Lamin B1 (right) and stained for HA (magenta) and DNA (blue) (d) Percentage of cells showing co-localisation of mEmerald-Lamin A/C (left respectively) with LAP1BNT/ LAP1B1–121/LAP1CNT P-values calculated by one-way ANOVA (d); *p < 0.05 Unprocessed western blots and numerical data are available in the Source Data Source data (a) WM983B cells stably expressing LAP1B-mRuby3 or LAP1C-mRuby3 transfected with mEmerald-lamin A/C or mEmerald-lamin B1 stained with SiR-DNA and displaying nuclear envelope blebs mEmerald-Lamin A/C and mEmerald-Lamin B1 in the main nucleus and in NE blebs of WM983B cells stably expressing the indicated LAP1-mRuby proteins (c) WM983A cells stably expressing LAP1C-mRuby3 and stained for Emerin and DNA (top) or NPCs (bottom) n = 671 and 605 for anti-Emerin and anti-NPC staining (e) Representative immunoblots for lamin A/C lamin B1 and lamin B2 expression levels in WM983B cells after 72 hours of siRNA depletion of lamin A/C lamin B1 or lamin B2 with siGENOME SMARTpools (f) Representative pictures of WM983B stably expressing GFP-NLS (green) and stained for endogenous LAP1 (magenta) and DNA (blue) and transfected with the indicated siRNA NE blebs without LAP1 staining indicated by arrowhead (g) Percentage of nuclear envelope blebs containing LAP1 upon depletion of lamin A/C lamin B1 or lamin B2 with siGENOME SMARTpools in WM983B cells (h-j) FRAP analysis of LAP1 isoforms at the main nuclear envelope (h) and at nuclear envelope blebs (i) in metastatic melanoma WM983B cells stably co-expressing LAP1B-GFP and LAP1C-mRuby3 White arrowheads indicate bleaching at the main nuclear envelope and at the nuclear envelope bleb graphs show the mean and error bars represent S.E.M In i,j graphs show the mean and error bars represent S.D P-values calculated by one-way ANOVA (g); *p < 0.05 Source data (a) Representative immunoblot for LAP1 expression levels in primary melanoma WM983A cells stably expressing GFP-NLS and LAP1C-mRuby3, LAP1B-mRuby3 (LAP1 M122A) or LAP1-mRuby3, related to Fig. 5a–d c) Percentage of less metastatic A375P cells stably expressing GFP-NLS A375P stably expressing GFP-NLS and LAP1-mRuby3 LAP1B-mRuby3 or LAP1C-mRuby3 that translocated their nuclei (b) and displayed nuclear envelope blebs (c) after a second round of transwell migration through 5-μm pores e) Percentage of less metastatic melanoma A375P cells stably expressing GFP-NLS and LAP1B-mRuby3 LAP1BΔCBR-mRuby3 or LAP1BR563G-mRuby3 that translocated their nuclei (d) and displayed nuclear envelope blebs (e) after a second round of transwell migration through 5-μm pores g) Percentage of primary melanoma WM983A cells stably expressing GFP-NLS and LAP1B-mRuby3 or LAP1BΔ1-72-mRuby3 or siRNA resistant LAP1B-mRuby3 (LAP1BR-mRuby3) LAP1BΔ1-72-mRuby3 (LAP1BΔ1-72R-mRuby3) or LAP1BΔCBR-mRuby3 that translocated their nuclei (f) and displayed nuclear envelope blebs (g) after a second round of transwell migration through 5-μm pores upon treatment with LAP1 siRNA#1 OnTarget LAP1 siRNA#1 targets a sequence present within the CBR of LAP1 i) Percentage of WM983A cells stably expressing GFP-NLS and LAP1C-mRuby3 or LAP1CR441G-mRuby3 that translocated their nuclei (h) and displayed nuclear envelope blebs (i) after a second round of transwell migration through 5-μm pores Graphs show the mean and error bars represent S.E.M P-values calculated by one-way ANOVA (b-g) and two-tailed t-test (h Source data A375P or A375M2 tumours grown intradermally in NXG mice A375P endpoints considered at same-time and same-volume as A375M2 (c) Representative images and QuPath mark-up (map red) of SOX10 staining and (d) quantification of dermal invasion in Day 42 WM983A and WM983B tumours grown intradermally in NXG mice Dashed lines represent the boundary between proximal invasive front (PIF) and the distal invasive front (DIF) (e) Representative images and QuPath mark-up (map red) of CITED1 staining and (f) quantification of dermal invading cells in Day 24 and Day 36 A375P tumours and Day 24 A375M2 tumours grown in NXG mice (g-j) Representative images (g,i) and percentage of tumour cell nuclei according to LAP1 intensity score (h,j) in the tumour body (TB) and invasive front (IF) of Day 55 WM983A (n = 8) and WM983B (n = 4) tumours (g,h) or in TB and IF of Day 33 A375P tumours (n = 8) and Day 33 A375M2 tumours (n = 8) grown subcutaneously in SCID mice Significant p values shown for LAP1 score ‘3’ (k) Representative images and QuPath mark-up of GFP-NLS staining (map (l) quantification of dermal invasion in Day 28 intradermal tumours (n = 10 in all conditions) and (m) in-vitro proliferation curves of A375P cells stably expressing GFP-NLS LAP1B-mRuby3 GFP-NLS LAP1C-mRuby3 and A375M2 GFP-NLS cells horizontal lines show the median and whiskers show minimum and maximum P-values calculated by one-way ANOVA (f,l) scale bars are 50 μm (10 μm in enlargements) Source data Signalling regulation gene sets enriched in A375M2 nominal P value for the enrichment score calculated by phenotype-based permutation test familywise-error rate (FWER P value) and the position in the ranked list at which the maximum enrichment score occurred (RANK MAX) of signalling regulation gene sets enriched in highly metastatic melanoma A375M2 cells Nuclear membrane gene sets enriched in A375M2 familywise-error rate (FWER P value) and the position in the ranked list at which the maximum enrichment score occurred (RANK MAX) of nuclear membrane gene sets enriched in highly metastatic melanoma A375M2 cells Cell division gene sets enriched in A375M2 familywise-error rate (FWER P value) and the position in the ranked list at which the maximum enrichment score occurred (RANK MAX) of cell division gene sets enriched in highly metastatic melanoma A375M2 cells Organelle organization gene sets enriched in A375M2 familywise-error rate (FWER P value) and the position in the ranked list at which the maximum enrichment score occurred (RANK MAX) of organelle organization gene sets enriched in highly metastatic melanoma A375M2 cells Cellular localisation gene sets enriched in A375M2 familywise-error rate (FWER P value) and the position in the ranked list at which the maximum enrichment score occurred (RANK MAX) of cellular localization gene sets enriched in highly metastatic melanoma A375M2 cells Cellular development gene sets enriched in A375M2 familywise-error rate (FWER P value) and the position in the ranked list at which the maximum enrichment score occurred (RANK MAX) of cellular development gene sets enriched in highly metastatic melanoma A375M2 cells Cytoskeleton organization gene sets enriched in A375M2 and the position in the ranked list at which the maximum enrichment score occurred (RANK MAX) of cytoskeleton organization gene sets enriched in highly metastatic melanoma A375M2 cells Cellular movement gene sets enriched in A375M2 familywise-error rate (FWER P value) and the position in the ranked list at which the maximum enrichment score occurred (RANK MAX) of cellular movement gene sets enriched in highly metastatic melanoma A375M2 cells Cellular transport gene sets enriched in A375M2 familywise-error rate (FWER P value) and the position in the ranked list at which the maximum enrichment score occurred (RANK MAX) of cellular transport gene sets enriched in highly metastatic melanoma A375M2 cells Membrane remodelling gene sets enriched in A375M2 familywise-error rate (FWER P value) and the position in the ranked list at which the maximum enrichment score occurred (RANK MAX) of membrane remodelling gene sets enriched in highly metastatic melanoma A375M2 cells Nuclear matrix gene sets enriched in A375M2 familywise-error rate (FWER P value) and the position in the ranked list at which the maximum enrichment score occurred (RANK MAX) of nuclear matrix gene sets enriched in highly metastatic melanoma A375M2 cells familywise-error rate (FWER P value) and the position in the ranked list at which the maximum enrichment score occurred (RANK MAX) of biosynthesis gene sets enriched in highly metastatic melanoma A375M2 cells Clinical information for patients with primary melanoma The table shows the average patient age ± s.d. the number and percentage of patients according to gender and the number and percentage of tumours according to location for human patients with melanoma in cohorts A and B Clinical information for patients with metastatic melanoma and the number and percentage of metastases according to location for human patients with melanoma in cohorts A and B The table shows the PCR primer name and nucleotide sequence The table shows the siRNA target and siRNA oligo sequence The table shows a description of the BioWave programme steps Representative SBF-SEM reconstruction of the nucleus of a metastatic melanoma WM983B cell with an intact NE bleb Representative correlative live imaging before fixation for CLEM of the nucleus of a metastatic melanoma WM983B cell stably expressing GFP-NLS (green) with an intact NE bleb Representative SBF-SEM reconstruction of the nucleus of a metastatic melanoma WM983B cell with a ruptured NE bleb Representative correlative live imaging before fixation for CLEM movie of the nucleus of a metastatic melanoma WM983B cell stably expressing GFP-NLS (green) with a ruptured NE bleb Representative movie of NE rupture in a WM983A cell stably expressing GFP-NLS (green) Representative movie of NE rupture in a WM983B cell stably expressing GFP-NLS (green) FRAP of LAP1 isoforms in metastatic melanoma cell Representative movie of FRAP in a WM983B nucleus stably co-expressing LAP1B-GFP (LAP1 M122A) (green) and LAP1C-mRuby3 (magenta) and with an NE bleb FRAP was measured at the main NE and at the bleb Representative movie of FRAP in a WM983B nucleus stably co-expressing LAP1B-GFP (M122A) (green) and LAP1C-mRuby3 (magenta) and with an NE bleb Numerical source data and exact P values for Fig Numerical source data and exact P values for Extended Data Fig Download citation DOI: https://doi.org/10.1038/s41556-022-01042-3 Anyone you share the following link with will be able to read this content: a shareable link is not currently available for this article Sign up for the Nature Briefing newsletter — what matters in science Yaiza’s Mayor Óscar Noda has registered his “surprise” that the public company Puerto Canarios has submitted a request to deregister with the Association of Mediterranean Cruise Ports if it is confirmed “it will leave Playa Blanca out of the market and seriously undermine the economic interests of Playa Blanca and Yaiza.”  He has demanded explanations from Puertos Canarios and the Canarian Government Yaiza has intended to open Playa Blanca’s port to medium-size and boutique cruisers since it was extended but has not yet received the authorisation to do so If the Canaries are removed from Medcruise’s schedules it will also affect ports in Fuerteventura and Noda claims this will damage the Canaries as a whole On January 5th three wise guys will arrive at all corners of Lanzarote following yonder star and their parade is one of the most eagerly-awaited children’s events on the island Although more and more Spanish kids receive gifts from Santa its the Three Kings who have traditionally brought Christmas presents here and they do it on the night of the 5th January long after much of the rest of the world has forgotten about Christmas but recently in Spain their identities have been adapted to reflect the influence of the church in three of the world’s continents usually portrayed as a white man with a white beard with a dark beard and often wearing Arabian-influenced costumes Baltasar is usually portrayed as a young black King from Africa In the past this would often involve a council worker smearing his face with burnt cork or boot polish but more recently the job has been given to a local from the Spanish/African community the Kings will arrive and do a whistle stop tour of local villages parading on camels or in pen-topped vehicles throwing boiled sweets to crowds of children they will stop to receive the letters of children who will then head to bed dreaming of what awaits them next morning ARRECIFE 6pm: The largest parade on the island will depart from Puerto Naos and head to the Parque Islas Canarias TEGUISE 9am onwards: Tour of the municipality Parade in La Villa de Teguise at 7pm 6.30pm: Parade in Caleta de Sebo TÍAS 11.30am: The Kings will arrive by boat at Puerto del Carmen’s harbour before parading from C/Teide to C/ Los Afrechos TINAJO 5.30pm: Parade starts at football ground and ends at plaza de San Roque The Blue Flags for Playa Blanca’s town beach and Puerto Calero have been hoisted this week by the Yaiza Mayor and Ayuntamiento councillors Yaiza hoisted its newly renewed Blue Flags at the town beach in Playa Blanca and at Puerto Calero The hoisting of the flags was attended by Yaiza Mayor Noda stated that the two flags “give greater value to Yaiza as a tourist destination of the highest level in the Canary Islands” later stating that “Yaiza Ayuntamiento renews its commitment to invest in the beach [in Playa Blanca] within the scope of its powers so that our neighbours and tourists continue to enjoy a placid and emblematic location.” Medina described it as “a symbol of Playa Blanca with presence in the various formats of tourism promotion being also an important location for the practice and exhibition of local sports such as wrestling and sailing.” Noda emphasised the work of businessman José Calero “it is fair to publicly recognise the great investment effort reflected in 40 years of trajectory and 29 consecutive blue flags apart from other quality seals achieved by the marina in four decades of history” Puerto Calero is the only marina in Lanzarote with a Blue Flag ALDI has opened its first ever supermarket in Playa Blanca which is now the third supermarket on Lanzarote ALDI maintains its commitment to expansion in the Canary Islands with the supermarket chain’s first opening in the archipelago of 2025 bringing its total number of shops in the Canary Islands to 16 The company plans to open four new supermarkets in the Canary Islands this year of the nearly 40 planned for the whole of Spain where it has strengthened its position since its arrival in 2022 “Since we arrived in the Canary Islands more than two years ago our aim has always been to offer savings opportunities to more and more Canarian households,” said José Luis Redondo “One of the keys to our low prices are our trusted relationships with more than 50 local suppliers which is why 20% of our products come from the Canary Islands,” added Redondo The inauguration of the new ALDI in Playa Blanca was attended by David Mille Pomposo the Canarian Government’s Director General of Trade and Consumer Affairs “ALDI has become a very important operator in our market with a significant degree of acceptance by both consumers and producers due to its commitment to local produce,” said Mille The event was also attended by Yaiza Mayor Noda thanked “the confidence placed in Yaiza as the main beneficiaries are the residents of the municipality and the entire island of Lanzarote because they will have a cheaper shopping basket and a new alternative to purchase quality products The council is aware that resolving issues quickly is in the interest of the entire population.” The ALDI supermarket in Yaiza-Playa Blanca is open to the public from Monday to Sunday from 8:30am until 10pm consumers will find a wide range of quality products at low prices with a focus on own brands – nearly 9 out of 10 products are own brands – and on local and national origin 20% of ALDI’s range in the Canary Islands comes from more than 50 suppliers in the archipelago who supply the supermarket chain with more than 360 locally grown products ALDI will be offering exclusive offers and holding weekly and fortnightly promotions to make it easier to save on shopping baskets Yaiza Ayuntamiento reopened Playa Blanca’s town beach on Thursday after it was closed due to water contamination the previous Sunday Playa Blanca’s town beach was closed again due to water contamination despite claims from the Popular Party of Yaiza that it was due to sewage spills again Yaiza councillor Daniel Medina told La Voz “it was water with chlorine from a swimming pool.” Medina added that the pool was “probably emptied and reached the beach through the sewage system” The beach reopened this Thursday and was jam-packed that afternoon with bathers and swimmers enjoying the small beach once again A 45-year-old man was rushed to hospital in serious condition after being rescued from the sea off the coast of Yaiza according to a report by the Emergency Services Coordination Centre (CECOES) The incident occurred around 5:00pm yesterday afternoon (Sunday) when an alert was raised indicating that a boat was heading towards Marina Rubicón port with a person onboard in cardiorespiratory arrest The affected person apparently fell off the boat into the water prompting his friends to perform CPR to try and resuscitate him while navigating back to the port paramedics took over and continued the resuscitation efforts and immediately transported him by ambulance to Hospital Molina Orosa where he is receiving urgent treatment after being revived The Local Police and Guardia Civil officers were also dispatched to the scene to assist with the incident and coordinate the transfer of the affected man Authorities are continuing to investigate the circumstances surrounding the incident to determine the exact cause of the accident Hailing from Puerto Rico and trained at The Royal Central School of Speech and Drama in London Yaiza Figueroa is noted for A Beautiful Death The Befuddled Box of Betty Buttifint and the lead in Grace and The Showreel who finds herself unable to build new memories following an experiment to generate and travel through a wormhole The taut sci-fi thriller follows Ana’s desperate efforts to understand what happened and to find out who—or what—is behind the rising confusion in her life Yaiza reveals what attracted her to this intellectual thriller and what she drew upon to bring Ana to life This was a surprisingly interesting film about a compelling scientific topic Yaiza Figueroa: I was originally cast for a supporting role The protagonist and his supporting actor were both male Then I was given another script by director Keir Burrows because we had worked before in another short film I was drawn to exactly what you mentioned earlier—the film’s multi-level intellectual take on the subject matter When they changed the gender of the lead and offered me the protagonist It gave the lead an added dimension as well as ethnic diversity Touching on immigration appealed to me because I was going through the same sort of loneliness Ana was facing I was in the UK when they were talking about Brexit and I was feeling all the emotions surrounding immigration I was thankful in getting the lead because most Latinas are often handed housemaid or sexy bombshell roles You rattled off highly technical terms like a Ph.D chemist Did you immerse yourself in the technology before taking on this project ‘I feel like I have a quantum physics degree now.’ I spent three days in the lab working with the production designer I had to become familiar with all the machines What did you find most challenging about portraying Ana Yaiza: I felt distant from the sci-fi aspect of the film so I had to work twice as hard to sound natural What did you draw from to portray a woman struggling with self-identity Ana appears untethered to her past and at some point how did you approach bringing that out in Ana Yaiza: I was also doing a short called The Showreel about an immigrant trying to make it as an actress in London But She was from the Middle East and she was disconnected from reality by playing different roles in life So we had been working with that idea from that short film The film obliquely segued into animal rights Are you an advocate of protecting animals in medical research Yaiza: It’s funny because the first draft of the script did not have that as a secondary theme Do you believe we will ever develop teleportation If so do you think a person’s soul will remain intact Maybe I feel close to introspective characters I like the challenge of portraying a character that has so many things going on inside I’m currently doing a light comedy TV series called Such is Life and I’m a sports reporter for a TV channel here—I love sports I’ll probably move to New York in a year or two and do more films Anti Matter will be in select theaters and VOD September 8th Our website uses cookies to improve your experience The Papagayo Arena hotel has been operating without a license for years and although the Lanzarote Cabildo and the Canary Islands Government seemed to throw it a lifeline its legal situation does not seem to be close to being resolved The Yaiza Town Hall issued a statement last night in which it clarified that it cannot resolve the urban planning license for the Playa Blanca complex without the approval of Costas and without making the public access road to the coast usable again that they built over which the Cabildo of Lanzarote began to process this Monday although they assured that these were two different procedures “The Yaiza Town Hall cannot grant a planning licence without having official tourism authorisation from the Cabildo,” the council responded bluntly in a statement The City Council is protected by Law 2/2019 on the Renewal and Modernisation of Tourism in the Canary Islands which states that the implementation of new tourist accommodation in Lanzarote Gran Canaria and Tenerife is “subject to prior authorisation from the respective island councils” prior authorisation is required for renovations and extensions of hotels the Yaiza Town Council also needs the approval of Costas which has placed the complex in the coastal protection zone Costas has reviewed the beach boundary and has confirmed that the width of the right of way bordering the sea is 100 metres and not 20 as thought the resolution of Costas orders “to rectify the legal situations in the registry that contradict the approved boundary If the complex doesn’t have both authorisations it will not be able to issue any resolution on the project to legalise the hotel” it is forbidden to build houses or hotels of any kind the City Council has announced that it will appeal the new boundary “not specifically because of the Papagayo Arena hotel but because of the wide area of ​​the municipal territory affected.” The hotel's license was revoked in the “Yate” case ruling which was one of the darkest periods for Yaiza and Playa Blanca granted dozens of licenses "with no legal basis other than his whim," according to the ruling the complex has more floors than allowed and occupies a public access road to the coast This is why the Yaiza City Council stresses that in order to begin the project to legalise the complex it must remedy the occupation of the public pedestrian access roads to the coast A total of 904 secondary school students from Lanzarote & other Canary Islands will participate in the IES Yaiza Triathlon this Friday Of the 904 secondary students that are taking part from Lanzarote there are 94 from IES Playa Honda there are participants from IES Agustín Espinosa In the 25th edition of the IES Yaiza Triathlon there will be various categories for students under 20 years of age with 380 boys who will form 102 male teams 135 girls for the 36 female teams and 253 participants who form the 65 mixed teams as well as 40 triathletes in the male individual category and 4 for the female individual and 7 triathletes for the male individual category and 5 in the female individual category The participants will gather at IES Yaiza at 8:15am to be welcomed and given their race numbers before heading down to the beach at Puerto Calero to start the swimming part of the race at 10am After covering a distance of 800m in the swimming race they will transition to a short foot race to the Hotel Secrets where they will collect their bikes and start the 8,500-metre cycle race along a dirt track that will end at the football pitch at the IES Yaiza at the football pitch they will take part in a 3,500-metre mixed circuit race before making a final effort for the finish line With Lanzarote’s population growing steadily and tourism stronger than ever the island’s road network has come under increasing pressure There are now 140,000 vehicles on Lanzarote and the greater independence of tourists means that more and more hire cars are on the road every year Transport was just one of the issues at the heart of April’s protests against the effects of mass tourism with the island’s public transport system creaking under added pressure and chaotic queues of traffic at many of the island’s touristic attractions there are no serious plans to reduce Lanzarote’s heavy reliance on the motor vehicle the island has been forced to address the fact that many of its roads need improvement There are several road building plans in the pipeline for the next few years Plans to widen the LZ-40 road between Indelasa and the Restaurante El Toro are likely to be carried out within the next three years The €40 million project will be approved this year Playa Blanca’s increasing importance as a resort a port and a residential area has led to pressure on the LZ2 where tailbacks caused by heavy vehicles and coaches are frequent The Cabildo and Yaiza Ayuntamiento agree on the need to build a continuous dual carriageway between the resort and Yaiza but the Canarian Government has pledged to commission one within its current term It is hoped that the second underpass at Playa Honda which will filter off traffic coming from Arrecife to Deiland will ease pressure on the notorious Playa Honda double roundabout but bigger plans are in the works to relieve congestion in Playa Honda the construction of a brand new 8-kilometre dual carriageway linking the airport with the hospital at Arrecife This road would be located to the north of Playa Honda’s industrial zone relieving pressure on the LZ-2 road considerably The second option is the burial of the LZ-2 through Playa Honda This would allow lighter traffic above ground and permit Playa Honda’s residential and industrial zones to be linked This option is favoured by environmentalists and studies claimed that it would also be cheaper than building an entire new road although Cabildo President Oswaldo Betancort has criticised the new road option saying “I will not allow more territory to be lost.” However continued indecision could mean the loss of funds allocated for improvements Getting onto Arrecife’s outer ring road (and on towards Costa Teguise for example) from the main airport road involves traffic moving into the fast left-hand lane on a poorly signposted stretch A project for a raised roundabout has been drawn up but objections have been lodged by the César Manrique Foundation and the PLZT21 collective The project will be licenced by the end of the year The Canarian Government plans to approve a €60 million project to bury part of the main road going past the hospital with work starting in the next legislature (after 2027) The existing road split the zone of Argana Alta in two and has been the scene of a number of accidents as pedestrians try to get across Roundabout fever is set to continue in the north of the island with plans for a roundabout between the Jameos del Agua and Yé Another roundabout will improve connections to Jameos and Cueva de los Verde while a third will be built on the exit from Punta Mujeres The road will also be resurfaced and widened to ensure greater safety for cyclists The blueprint for this project is currently awaiting approval from the Canarian Government’s Ecological Transition department The road to El Golfo via Los Hervideros has been closed since a sinkhole appeared in 2021 geological surveys are taking place to establish how This road through beautiful volcanic scenery is an accident blackspot mainly due to its width and poor condition Yaiza Ayuntamiento have removed electric scooters from three rental companies in Playa Blanca after they were found to lack the necessary licences announced that they had issued a ten-day deadline for electric scooter companies to present the necessary licences and paperwork to rent out scooters in Playa Blanca explained that any companies that failed to provide the necessary documentation would have their scooters removed from the southern resort Up until this week there had been no news on the follow-up to Yaiza Ayuntamiento’s statement with many residents taking to social media to call attention to the fact that the scooters remained it has been announced that three companies have had their scooters removed by Yaiza Ayuntamiento after they failed to prove that they had the documentation to rent out the vehicles stated that “we cannot allow these vehicles circulate on our roads without the relevant authorization and therefore we have proceeded to its withdrawal” Óscar Noda stated “Our intention is not to prohibit the use of these scooters but to regulate it because there are many neighbourhood complaints regarding their use and the way they are left abandoned on sidewalks and roads obstructing the passage of pedestrians among other inconveniences and deficiencies that we note and want to correct we are also working on a set of conditions so that companies wishing to provide this service can do so but complying with a series of requirements to do it in the best possible way and without causing inconvenience to the neighbours of Yaiza” has spoken to Lancelot regarding the recent camel abuse controversy after a video surfaced of a young camel buckling under the weight of two workers last week Last week a video surfaced online showing two camel handlers sitting in the saddles either side of a young camels back The camel was unable to stand with the weight of the two men they urged the mother to move forward to pull the young camel to its feet The video showed the young camel grunting as its legs buckled under the weight of the two men The video was recorded by a Spanish tourist who later published the video to Instagram The video quickly gained traction online and found its way onto Facebook Yaiza Ayuntamiento announced that they will take action and started a process to establish the correct penalty the camel handler involved in the video has apologised publicly saying The Mayor of Yaiza recently spoke to Lancelot regarding the incident Noda defended the camel sector making it clear that what happened is a “one-time event” and is far from the way that the camels are usually treated “It is clear that we will take measures for what happened but to go as far as to suggest that the activity [camel ride tours] should be eliminated… there are families that live from it “It is an activity that has been passed down for generations and we will continue to regulate and improve the service so that is it done in the best conditions.” Noda stated “we have already identified the company that is now being review especially in relation to treatment of animals and appropriate measures will be taken… We want to have a meeting with everyone involved in the sector to ensure that this does not happen again.” For regular updates, pictures and videos of Lanzarote be sure to like and follow our Facebook page “Gazette Life Lanzarote”. Text description provided by the architects Gentrification is cruel to the historical centres of cities diverse and well-equipped neighbourhood is becoming a highly coveted luxury It's necessary to regulate the real estate market and mass tourism to democratize access to housing in densely populated areas in addition to multiplying its share of affordable housing how to build housing in the developed centre if it is the place where the available space is more expensive and scarce cities are proposed to fill in the cavities of their built-up teeth It understands vacant lots, properties that have not exhausted their buildability and even excessively large public spaces as places of opportunity to house residential units that using modular prefabrication with criteria of urban achieve faster execution that is more economic fair and sustainable than conventional public housing previously used as an extension of the adjacent public space it houses the extension of a nearby sanitary facility and it contains a total of twelve accommodations of which eight are one-bedroom and four are two-bedroom apartments All the accommodations have a minimum of two facades The northwest facade opens onto a courtyard that contains the vertical nucleus of accesses facing a narrow street, is clad with wooden balcony doors of vertical proportion like the buildings of most of the historic centre the four largest accommodation units have wider openings The facades are ventilated and their thermal insulation gives the building the best energy-efficient features Its exterior walls have been resolved with a translucent polycarbonate cladding clear skin increases the luminosity of the accommodation while subtly reflecting the surroundings thereby improving street lighting without compromising the privacy of its inhabitants You'll now receive updates based on what you follow Personalize your stream and start following your favorite authors If you have done all of this and still can't find the email Yaiza Ayuntamiento has issued a ten-day deadline for electric scooters to be removed from the streets of Playa Blanca A council announcement directed at companies who rent the scooters requested the voluntary removal of all scooters within a period of ten days the council will remove and impound them itself (as has occurred in other parts of Lanzarote) The reason for the ultimatum is “the absence of qualifications necessary to carry out such activity” – probably a reference to the way scooter companies operate without a municipal business licence.  Yaiza Mayor Óscar Noda explained that the council was preparing new regulations to govern  personal mobility vehicles and said  “We have had citizen’s complaints about the invasion of scooters into public spaces  on sidewalks and pedestrian footpaths such as Calle Limones or the promenade so until the by-laws come into effect we intend to guarantee the safety of pedestrians and also requesting the collaboration of private owners who also may not circulate on pedestrian streets The scooter is an alternative for mobility but we cannot ignore the fact that it is a vehicle and like any other vehicle it is obliged to obey road signs.” emphasizes Students from the IES Yaiza school were all given coloured markers and the freedom to draw on a new mural in the municipality IES Yaiza school students were allowed to let their creative juices flow as they were each given a handful of coloured markers and a blank mural to draw whatever they liked on it This is not the first time that the Yaiza Ayuntamiento has involved its school students in practical activities For more than two years they have involved students in workshops and other projects to give them a voice in social “Which is why we have several projects in the works for sports facilities” reported that “the students worked on the new mural with the help of the artist Iván T.” Not only did the students express their creativity and interests but they also took the opportunity to raise awareness for social issues “Our educational centres are essential spaces for sharing ideas of social change and wellbeing” For regular updates, pictures and videos of Lanzarote be sure to like and follow our Facebook page “Gazette Life Lanzarote” Feature Films Database Southern Mediterranean films database Scriptwriters European Film Schools Production Companies Distributors International Sales Submit a Film Industry Reports Co-Production Podcast Online Screenwriting Training Course Guided Course for Feature Film Writing Script Analysis Analysis of the potential of your series Cineuropa's Training Catalogue Film Festival Photographs Newsletter Photogalleries EUFCN Location Award Euro Film Fest 27 Times Cinema GoCritic! Advertise on Cineuropa Logos and Banners FUTURE FRAMES 2020 “Why should film festivals get scared just because you can see some genitalia?” by Laurence Boyce 29/06/2020 - Spanish filmmakers Yaiza de Lamo Maria Lorente and Mariona Vázquez discuss their short film DIYSEX Screening as part of 2020 Future Frames, European Film Promotion’s annual showcase of student short films that this year will take place online during Karlovy Vary’s Eastern Promises DIYSEX is a powerful Spanish documentary examining female attitudes towards sex and pornography The film follows a protagonist who wants to make a porn film that reflects her wants and desires she asks sex workers about the porn industry and works her way to making her own perfect film The film is the product of the collaboration between filmmakers Yaiza de Lamo Maria Lorente and Mariona Vázquez who met while doing the masters in Theory and Practice of Creative Documentary Filmmaking by UAB in Barcelona We wanted to find out more about the making of the film Cineuropa: What drew you all to making this documentary?Yaiza de Lamo Mariona Vázquez: We were really concerned about how sexuality is represented in media and mainstream pornography is the main source that people are used to watching We started questioning ourselves as well as our surroundings DIYSEX was born from an intimate need to answer some unanswered questions How do you work collaboratively on such a project especially one that initially seems to be based on the POV of one person?It’s a made-up person based on a little something of all of us we discussed a lot about literally everything We spent so many hours having conversations about why ‘this’ or ‘that’ wasn’t useful or representative the made-up protagonist is the link to all of our thoughts - even if don’t always agree – and provides a common area and a collective POV In talking frankly about sex was there ever any worry about ‘putting yourselves out there’ too much Or does working as a collective help minimise that?There were times that we thought what we were saying was too explicit but working as a group makes everything a little easier that way but it is true that pornography is still a highly taboo topic so it made us insecure as we exposed our own intimacy from the first line And we become part of this same stigma each time we have to explain what our documentary is about Did your views on porn change as you made the film?Before making this movie we just had an open mind and a will to learn We didn’t already know that virtually every famous and free porn site profits from mostly stolen content -which means no money or visibility for the sex workers It’s an industry where no one wants to pay for what they watch Paying for those huge porn sites doesn’t work and it just means that you are paying for stolen videos What other things surprised you?The whole process of how to make a different porn film is shown in DIYSEX and it shows how performers discuss what is going to be done When our audience watched both our performers sit down to talk about what parts of their bodies were off limits was something most of them weren’t expecting We think it’s a crucial conversation to show: it’s just a natural thing to do and a necessary thing to do in any kind of sexual activity Did you ever debate how sexually explicit the material you included in the film was going to be and whether this would cause problem with festival selections We did have long discussions regarding to the people and bodies that we were showing in the film but we didn’t talk that much about film festivals refusing our film because of this reason We also stand by the idea that porn is just cinema so why should film festivals get scared just because you can see some genitalia Please subscribe to our newsletter to receive more stories like this directly in your inbox 12/08/2020Production / Funding – Spain The Revolution of Muses is ready to begin 02/05/2025 Annegret Richter • Artistic director, Stuttgart International Festival of Animated Film“There’s no definition of which target group it has to be for; you can tell any story with stop motion” 02/05/2025 Sanja Božić-Ljubičić • CEO, Pickbox, Mediatranslations, Mediavision and NEM“We will always stay focused on the CEE region, a region that’s unique – it can be challenging, but it’s also incredibly rewarding” 30/04/2025 Mirko Goran Marijanac • Media sales executive, DeAPlaneta Entertainment“It’s all about using AI ethically, and making the most of its tools to boost efficiency in animation and distribution” 29/04/2025 Anne Pouliquen • Founder and Director, Futura Cinema“Futura Cinema acts as a bridge between cinemas, cultural innovation and technological solutions” 28/04/2025 Paulina Jaroszewicz • Distribution and marketing manager, New Horizons Association“What has changed in recent years is that we buy half of our line-up based on script – like for Carla Simón’s Cannes Competition title Romería” all interviews Subscribe to our newsletter to receive the most important daily or weekly news on European cinema Cannes 2025 Marché du Film AFCI runs its second annual Global Film Commission Network Summit at Marché du Film Festivals / Awards Czech Republic Czech Republic’s Anifilm goes sci-fi Distribution / Releases / Exhibitors Europe European Arthouse Cinema Day set to return on 23 November Cannes 2025 Marché du Film Indie Sales presents a three-star line-up at Cannes HOFF 2025 The Shadow and U Are the Universe win at Estonia’s Haapsalu Horror and Fantasy Film Festival Crossing Europe 2025 Awards The New Year That Never Came and The Flats crowned at Crossing Europe Cannes 2025 Marché du Film Be For Films to sell Love Me Tender in Cannes Cannes 2025/Sponsored Latvia set to shine bright at Cannes, led by Sergei Loznitsa’s competition entry Two Prosecutors Las Palmas 2025 MECAS/Awards Manuel Muñoz Rivas and Joana Carro win awards at the eighth MECAS Cannes 2025 Marché du Film Playtime to present some high-impact and entrancing trump cards at Cannes Production / Funding Italy Shooting begins on Walter Fasano’s Nino, a portrait of scoring maestro Nino Rota goEast 2025 Review: My Magical World Market TrendsFOCUSA busy spring festival season awaits the European film industry. Cineuropa will continue to keep its readers up to date with the latest news and market insights, covering the buzziest events, including Cannes, Kraków, Karlovy Vary, Tribeca, Hot Docs, Annecy, Brussels, Munich and many others Distribution, Exhibition and Streaming – 02/05/2025Slovak crime-thriller Černák becomes the highest-grossing film in domestic cinemasThe second film in the saga about a local mafia boss, directed by Jakub Króner, outgrossed its first part, which dominated Slovak cinemas last year Animation – 30/04/2025Mirko Goran Marijanac • Media sales executive, DeAPlaneta EntertainmentDuring our chat, the exec shared key insights from this year’s Cartoon Next and touched on the current climate for the animation sector Jaśmina Wójcik • Director of King Matt the First The Polish director discusses her approach to taking on a 1920s children’s literary classic in an unexpected way Želimir Žilnik • Director of Eighty Plus The Serbian director discusses his deep suspicion of ideologies in relation to his irresistibly charming latest feature, which follows a man whose life spans three political systems Paulina Jaroszewicz • Distribution and marketing manager, New Horizons Association Cineuropa sat down with the Polish distributor to discuss her company’s strategy as well as the connection between its distribution line-up and BNP Paribas New Horizons Festival’s programme Lorcan Finnegan • Director of The Surfer The Irish filmmaker discusses his mystery-thriller, how he created the character with Nicolas Cage and his approach to the use of colours in the film Privacy Policy The images used on this website have been provided by journalists and are believed to be free of rights if you are the owner of an image used on this website and believe that its use infringes on your copyright We will remove the image in question as soon as possible We have made reasonable efforts to ensure that all images used on this website are used legally and in accordance with copyright laws About us | Contact us | Logos and Banners Mission | Partners | Team | Donations | Terms and conditions The State Security Forces and the Emergency Services continued their search yesterday for the 26-year-old Czech man who disappeared on Tuesday evening after going for a walk in the Los Charcones area of Yaiza in Lanzarote looked for him for ten hours yesterday from 8.30am until 6.30pm incorporating the Helimar rescue helicopter and Local Police drones along the coast Today (Friday) the search will resume at 8.30am along the same coast between Los Charcones and Faro Pechiguera but the police are asking anyone that may have any information regarding his whereabouts The aprop program for provisional housing launched by the City of Barcelona is designed to offer a swift and pragmatic response to emergency situations caused by shortage of housing keeping neighbors from having to leave gentrified districts sites where there is still buildable surface available as areas of opportunity for the construction of residential units These apartments in particular are built using modular prefabrication systems which make for a quicker and more sustainable execution than what is usual in public housing The City has promoted these residential developments to temporarily accommodate families ejected from the neighborhoods so the ecological footprint of the construction is considerably reduced they avoid energy waste and the emission of greenhouse gas related to massive use of reinforced concrete and steel cast for metallic structures These structures are also completely dismountable which reduces energy waste and residues from demolition processes The APROP in Barcelona’s Gothic quarter is a compact corner volume boxed in by party walls and that harbors at ground level an extension of a nearby sanitary infrastructure and in its four upper floors twelve living units – eight of them with two bedrooms The northwest facade flows out to a courtyard containing the communications core and metallic handrails resembling those found in the traditional buildings of the historic center the four larger apartments have wider windows and they incorporate thermal insulation that makes the building highly energy efficient The outermost skin is built of translucent polycarbonate this clear and bright skin brings in light and subtly reflects its environs improving street illumination without compromising the residents’ privacy there arent any match using your search terms A dispute between Yaiza Ayuntamiento and the company responsible for Playa Blanca’s new sports centre has arisen after it was discovered that modifications would need to be done to the original project The company are asking for a further €2 million to finish the extra work while Yaiza insists it can only provide €600,000 The works that require completion relate to the air conditioning system inside the building and several aspects on its exterior various sports courts and a children’s playground Yaiza is considering issuing a new tender for the remaining works “What is important is that the works are finished properly,” said Mayor Óscar Noda who is confident that the pavilion will be completed by the end of the year “come what may.” has retained its gold medal at the Bacchus 2024 International Wine Competition The Bacchus International Wine Competition is Spain’s leading event in the world of wine and is open to wines vermouths and wine-producing spirits (piscos A unique opportunity to recognize the highest quality elaborations endorsed by a panel of more than 80 national and international tasters No wine event held in Spain manages to bring together over four days such a team of wine tasting experts as that of the Bacchus panel of judges More than a hundred names that combine diverse backgrounds with professionalism and experience In the 2024 edition of the Bacchus competition almost 2000 wines were present produced by wineries from across 19 different countries in the world Bodegas Vega de Yuco’s “Esencia Yaiza” white wine has made a name for itself on Lanzarote not only for its taste but also for its unique and recognisable bottle Many tourists and residents choose to keep the bottle as decoration after finishing it On their website the bodega stated that they receive the gold medal “great enthusiasm this new recognition for the Malvasía Volcánica of the Esencia Yaiza line with all the winegrowers and winemakers and the Vega de Yuco team that make it possible” You can find the wine in various shops on the island, or buy online on their website Residents of Playa Blanca have denounced the bad smells coming from the sewage treatment plant on the road to Femes In response to complaints about the “unbearable smell” Yaiza Ayuntamiento have said that the plant is the responsibility of Lanzarote’s water utility Canal Gestión and urged residents to direct their complaints to the company El Diario reports that the owner’s community of Las Velas has lodged a complaint with Canal Gestión They have called for Canal Gestión to find a solution that guarantees air quality and stops the contamination that is being caused Yaiza residents gathered at the Playa Blanca seafront last weekend to watch the arrival of the Virgen del Carmen by boat The Nuevo Santo Domingo fishing boat carried the Virgen del Carmen to the Playa Blanca beach yesterday The town beach was packed with residents and tourists who gathered to watch as the Virgen del Carmen was lifted off of the boat and paraded through the town the Virgen was brought to the local church Concerts and street parades took places in the centre of town by the local Yaiza Vocal Association and municipal band Check out pictures from the day (@Ayuntamiento de Yaiza): Visitors enjoyed the Uga market last weekend which returned after 2 years of postponements and a 70,000-euro investment from the Yaiza Ayuntamiento the Uga market is back every weekend from 9am until 2pm Last weekend many visitors arrived at the market to enjoy it after so long and to buy locally grown products The enthusiasm from vendors on the day is proof that the return of the market also sees the return of “promoting agriculture which satisfies the demands of the customers who prefer zero-kilometre products while being a part of an activity that energises the people of Uga” has signed an agreement along with the Canary Islands Housing Institute Director for a 42,000 square metre plot in Playa Blanca to be used for the construction of social housing The 42,253 square metre plot is located at Montaña Roja and will be used as part of Yaiza Ayuntamiento’s sustainable social housing plan They are now waiting for the draft design and construction plans as well as the contract to put out to tender Approximately 126 homes will be built on the plot For regular updates, pictures and videos of Lanzarote be sure to like and follow our Facebook page “Gazette Life Lanzarote” Yaiza’s distinctive red taxis will raise their fares for the first time in six years after the Ayuntamiento approved the measure yesterday The standard daytime rate for each kilometre travelled will rise from 0.63 to 0.75 cents while the night-time rate will rise to 0.80 cents The flag drop fee – charged before any journey – will be €2.70 from 6 am to 10 pm which applies to stationery or slow-moving taxis will rise from €124 top €15.40 (€17 at night) The fare rises come in response to the increasing price of petrol and have been requested by cabbies for several months Tias and Arrecife also also raised taxi fares There are currently 67 taxis operating in Yaiza 12 of which are adapted for those with special needs This means that every time you visit this website you will need to enable or disable cookies again.