Equans has announced the second phase of Digital Realty’s PAR13 data center has been successfully delivered in Paris In a recent LinkedIn post the data center construction firm announced that the facility offers 20MW of IT capacity the facility spans 21,700 sqm (233,000 sq ft) and is expected to be joined by an additional building This will bring the total square footage to 581,250 sq ft (54,000 sqm) Plans for the data center were first announced in June last year the site was said to be expandable to 80MW of capacity Equans added the data center includes prefabricated piping Digital Realty has twelve other data centers in Paris Equans previously delivered Digital Realty’s PAR12 facility Earlier this year Mercury delivered the 19MW PAR9 facility to Digital Realty and PAR11 comprise the company’s Paris digital park Construction provider Equans has also delivered projects for data center providers such as Equinix The company’s biggest project is the Virtus Stockley Park Campus in London Data Centre Dynamics Ltd (DCD), 32-38 Saffron Hill, London, EC1N 8FH Email. [email protected]DCD is a subsidiary of InfraXmedia A file photo of Egyptian researcher Reem Hamed Seqens has acquired Novartis’ CGT CDMO CELLforCURE and its manufacturing site located in Les Ulis French contract development and manufacturing organization (CDMO) Seqens aims to strengthen its range of pharmaceutical solutions as a service provider to manage the development of cell and gene therapy (CGT) drugs through to commercialization “The CELLforCURE is focused on development and production of CGT officially marks the complete takeover of CELLforCURE and its CGT development and production site in Les Ulis by Seqens We are confident that this transaction will enable business continuity at the industrial facilities preserve its know-how and safeguard as many jobs as possible,” a spokesperson for Novartis told BioProcess Insider French CDMO CELLforCURE was established by LBF (Laboratoire français du Fractionnement et des Biotechnologies) in 2013 July 2018 Novartis selected CELLforCURE as its chimeric antigen receptor T-cell (CAR-T) therapy manufacturing partner after receiving European Medicines Agency (EMA) recommendation for Kymriah (tisagenlecleucel) approval 2019  Novartis acquired CELLforCURE to expand its capacity for CAR-T therapies which includes six manufacturing suites and will offer large-scale production services for clinical and commercial purposes the site has made it possible to treat 580 patients including one hundred children in four years Novartis said the site is one of the first modular units in Europe to enable large-scale industrial production of CGTs with annual production capacity of several hundred therapeutic batches Seqens and Novartis teams have worked together to find a favorable outcome for the site Novartis is committed to ensuring that Seqens has all the necessary requirements to achieve the best possible transition for the employees,” the spokesperson added this takeover is the result of the firm’s commitment to do everything possible to find the best solution for the site and its employees and has been made possible thanks to the work of social partners employees and the support of the authorities No financial details of the acquisition have been disclosed Journalist covering the manufacturing and processing sectors for biopharmaceuticals globally Feel free to reach out to me at: [email protected] CSL Seqirus signs pandemic preparedness plan with European Commission Ins & Outs: Biopharma players shuffle c-suite ranks American made: Companies continue to emphasize US manufacturing Transforming Protein Production: Lonza’s Comprehensive Solutions for Therapeutic Innovation Registered in England & Wales with number 01835199 Anthony Martial’s record-breaking move to Manchester United will not only catapult the teenager onto the world’s biggest soccer stage it will also transform the finances of a tiny sixth-tier club in the Paris suburbs The striker’s departure to the English Premier League will be a game changer for Martial’s first club based in a southwestern Paris suburb about 20km from the French capital who became the most expensive teenager in the history of soccer after United agreed to pay AS Monaco a reported fee of ￡36 million (US$55.5 million) learned his skills at Les Ulis from 2001 to 2009 the amateur club is also famous for having nurtured the likes of former Arsenal star Thierry Henry and Patrice Evra another Frenchman who wore United’s famous red jersey clubs that help to develop youngsters who are later transferred are entitled to compensation for all the training and education provided over the years The so-called “solidarity mechanism” works between the seasons of the player’s 12th and 23rd birthdays Martial left Les Ulis when he was 14 to join Olympique Lyonnais’ renowned training academy meaning that the club will receive three years of development fees — representing 0.75 percent of his transfer to United — worth an estimated ￡270,000 It is manna from heaven for a team playing four divisions below the professional leagues “It will cover up to four or five years of our budget,” Les Ulis coach Mamadou Niakate said on Wednesday “We are always struggling to make ends meet This money will help us secure existing jobs and renew our equipment we’ve been using the same footballs and training shirts over the past four years.” A small town of about 25,000 people that was built at the end of 1970s and then hit hard by economic recession Les Ulis is mainly known for its soccer school and its big housing projects After years of social tension related to poverty the city council has launched a rehabilitation scheme aimed at diversifying the housing supply and promoting greater social cohesion we try not to turn down anyone and we contribute to the mixing of populations,” Niakate said “We try to instill a proper football culture while insisting on school attendance at the same time.” said Martial’s transfer to United would bring much more money into the club’s bank account than those of Henry and Evra combined “Thierry was just an 11-year-old boy when he left so we did not receive anything because the solidarity contribution does not work if the player leaves the club before his 12th birthday He later paid for an artificial pitch for the club we received about 38,000 euros [US$43,000] in player development fees Our main satisfaction is that someone from Les Ulis is able to join such a prestigious club as Manchester United.” Since the news broke of Martial’s departure to the most widely watched league in the world the 750-member club has been coping with a plethora of new registration requests with dozens of children flowing to the Stade Jean-Marc Salinier to sign up there will be other great players among them,” said Niakate who has been working at the club since 1987 and is coaching Martial’s elder brother “Anthony was really above the rest,” Niakate said “On the very first day he registered with us but that’s still a long way from saying he would one day join United for 80 million euros.” While the fee United paid for Martial — who has made just 29 senior starts in his spells at Lyon and Monaco — has left many soccer fans perplexed Niakate is adamant the comparison with Henry is not premature share the same technical and physical qualities and have more speed than the rest of the field — and like Thierry Martial has the stuff of champions,” Niakate said With the automotive industry’s model in the process of being reshaped Alpine Cars knows it can count on the expertise of its engineering facility in Les Ulis – in the southern Paris suburbs – as it addresses the challenges associated with electrification describes the know-how his teams have acquired over a period of more than 20 years for much of that time perfecting Renault Sport-badged models Renault Sport Technologies officially became Alpine Cars on May 1 but the engineers working out of the engineering centre did not wait until that watershed date to switch their mindsets to Alpine matters.. We’re talking about the same team that revived the A110 by bestowing today’s car with the agile handling and level of driving enjoyment that forged the original’s reputation back in the day They succeeded in applying the same qualities to a modern car that can be driven in any circumstances At the same time, it is no coincidence that the A110 R's wing is made from composite materials. "Light weight is crucial to performance" notes Robert Bonetto. "The A110's all-aluminium, rivet-bonded chassis and bodywork incorporates exclusive technologies that assert our know-how in this field. And while the A110 R makes extensive use of carbon fibre, our A110 E-ternité prototype employs materials that are even more innovative, including flax fibre that is produced in Normandy." There is another area of expertise at the Alpine’s engineering centre that doesn't immediately strike the eye but which becomes apparent the instant you take to the road in one its cars and which, Robert Bonetto believes, has played a significant part in forging the facility's reputation - handling. In the days of Renault Sport, the weeks of development groundwork spent at such a demanding and varied proving ground as the Nürburgring contributed to the depth of the team's savoir-faire, not to mention the sensitivity of its test drivers. "They are capable of perceiving a difference of two millimetres in the width of a carbon wheel flange" says Robert Bonetto proudly. "This work also enabled the cars' set-up to be fine-tuned in a way that truly shaped the sports DNA that made us stand out." The fruit of all this work will be revealed in a few months' time. Until then, the brain cells of the engineers will continue to focus on maximising the pleasure it is possible to derive behind the wheel of an electric sports car! You don't have permission to access the page you requested What is this page?The website you are visiting is protected.For security reasons this page cannot be displayed Working with CellforCure for six months was apparently enough to convince Novartis that buying the CDMO outright would be worth the expense Novartis and CellforCure recently completed the technology transfer which will permit clinical supply production of Kymriah (tisagenlecleucel) to begin at CellforCure's Les Ulis site by mid-2019 At Les Ulis — which is located south of Paris —​ CellforCure has more than 38,000 square feet of space including nearly 24,000 square feet of Good Manufacturing Practice area The site has two GMP certificates from the French drugs regulator Novartis would acquire the site directly along with related adjacent land While it's not clear when LFB might decide Novartis said the transaction could close in the first half of 2019 The Swiss pharma plans to fund the transaction with cash on hand Novartis manufactures Kymriah for commercial use out of its site in Morris Plains It's building a facility in Stein and has inked a partnership with the Fraunhofer Institute in Germany as well to help support production of the complex treatment Rollout of Kymriah hasn't been completely smooth, however. Novartis has had difficulties manufacturing Kymriah up to specifications resulting in some product that — while deliverable to patients — can't be billed In the three months from July to September, Novartis recorded $20 million in sales of Kymriah which costs hundreds of thousands of dollars per patient Get the free daily newsletter read by industry experts More than three-quarters of private biotech investment tracked by BioPharma Dive between January and March was distributed via rounds worth at least $100 million which experts believe reflects a strategic shift Just two acquisitions in the first quarter a notable decrease from the six seen during the same period last year The free newsletter covering the top industry headlines Saturday’s stalemate at Bournemouth was not an easy day for Willy Kambwala Less than a week after a dominant display in only his second senior start for Manchester United, against arch-rivals Liverpool the 19-year-old defender was reminded of the realities of competing in elite Yet it was also Kambwala’s full-blooded 50-50 against Solanke that set the visitors up to score the first of their equalisers in the 2-2 draw and United’s unrelenting injury problems are likely to give the teenager more opportunities to put things right over the final six weeks of the season his Old Trafford career so far is a story of recovering from setbacks he joined them shortly before the close of the extended summer transfer window in October 2020 as one of six under-18s signed from overseas before the shutters came down due to Brexit regulations Just 16 years old at the time, Kambwala signed his contract at Manchester’s Hotel Football on the day Tottenham Hotspur ran out 6-1 winners at the adjacent Old Trafford Despite being the youngest of those six overseas teenagers United agreed a final package of up to €4million (£3.4m; $4.3m at current exchange rates) for him with French club Sochaux and in a break from protocol with academy players announced Kambwala’s signing with an image of him posing in a United shirt Kambwala had been brought to their attention by Mathieu Seckinger, an academy scout based in France who also identified Hannibal Mejbri who was signed the previous summer from Monaco’s academy Despite being born in Kinshasa, the capital of the Democratic Republic of Congo in central Africa, Kambwala is another product of the Paris banlieues — arguably the hottest of hotbeds in world football — and specifically Les Ulis with his family having moved to France when he was five years old it is probably because of Club Omnisports Les Ulis the local team that launched the careers of Thierry Henry is a coach at Les Ulis and a close friend of Evra’s and the former United left-back is a regular source of guidance and advice After completing his mandatory two-week self-isolation period under the pandemic regulations in place at the time, Kambwala debuted for the under-18s in a 4-0 win over their Derby County counterparts that showed why United had sanctioned that €4million fee dominating defensively while playing two years up That was the only glimpse of those abilities for a while a friendly against neighbours Salford City Kambwala suffered an ankle injury serious enough to require surgery and sideline him for the best part of a year Kambwala slowly worked his way back to fitness as best as he could while coping with the challenges any teenager would face living in a country they barely know at a time of Covid-19 lockdowns After an 11-month lay-off, he eventually returned in an 8-2 cup win against Birmingham City in September 2021 Yet even then, a tricky recovery period beset with minor pains and niggles prevented him from a consistent run of appearances and meant his contribution to that season’s successful FA Youth Cup campaign was being an unused substitute twice, although he still celebrated wildly in his club suit during the trophy presentation at Old Trafford after a 3-1 win over Nottingham Forest Kambwala has therefore played relatively little academy football for a prospect United signed three and a half years ago with the majority of his appearances at the under-18 and under-21 levels coming over the past two seasons Yet that has only made the France Under-17 international determined to make up for lost time is known for clocking in early at United’s Carrington base before training to get through additional injury prevention work — often two and a half hours before the rest of the squad are due to arrive He has always been a warm and friendly presence around Carrington making an effort to say hello to staff in the mornings and engaging in conversations rather than sitting engrossed in his phone while waiting for a taxi to pick him up from reception Kambwala had typically been one of the quieter players in the academy dressing room Now, he is more vocal, more confident, and showing more personality every day — something that was on display in that game against Liverpool when, after chasing back to make a last-ditch recovery tackle on Darwin Nunez he turned to the Stretford End and urged the fans to raise the volume A relentlessly positive attitude has helped carry him through the more challenging spells and made him a popular member of the squad Kambwala is especially close with goalkeeper Andre Onana who has offered the teenager advice and mentorship since his breakthrough into the first-team setup — United’s official X account shared an image of Onana putting Kambwala in a playful headlock last Thursday Religion was a great comfort to Kambwala during that long spell recovering from injury and remains a major part of his life attends church regularly and counts a copy of the Bible as one of his most prized possessions It is also an integral part of his pre-match routine Kambwala often takes a moment of quiet reflection in the dressing room before games, either reading the Bible or praying, to help him focus and find inner peace. That especially helped at the London Stadium just before Christmas last year as he prepared to make his senior debut in what turned out to be a 2-0 defeat against West Ham United He turns to his faith “every single moment where I feel in my heart I need it” Just saying thank you for the opportunity.” United’s defensive injury crisis has handed Kambwala a chance to impress Manager Erik ten Hag had other options to deal with the spate of absences in his back line, such as dropping midfielder Casemiro deeper but has trusted that Kambwala can cope with the exposure Kambwala will enter the final year of his contract this summer and there is no one-year extension for the club to trigger automatically United have no plans to lose him on a free And Kambwala has no place he would rather be In April 2018, he visited Old Trafford with a group of his Les Ulis team-mates at the invitation of Martial and watched the 1-0 loss to relegation-bound West Bromwich Albion, which confirmed Manchester City as that season’s champions “It drove me crazy to see them playing on my field without being able to act,” Kambwala told French newspaper Le Parisien earlier this year thrust into this opportunity by circumstances beyond his control The coming weeks will tell whether this talented young defender takes it Rebuilding Old Trafford: What the local residents and businesses think Mark Critchley is a football writer for The Athletic, covering Manchester United and Manchester City. Mark joined after five years as The Independent's northern football correspondent. Follow Mark on Twitter @mjcritchley One of the most celebrated strikers in history With a career spanning more than three decades Thierry Henry has come a long way since his humble beginnings in Les Ulis as a second-generation immigrant from the French overseas territories in the Caribbean Living in the tough Parisian suburb and housing project with his parents it was here that he began his footballing career at the local club is a global sports and style icon who has enjoyed an impressive career both on and off the pitch most notably spending eight years at Arsenal FC under coach Arsène Wenger. That tenure saw him become the club’s all-time top scorer with a record-breaking 228 goals He went on to join Spanish club Barcelona and since retirement has forged a successful career as a TV pundit coach of the French national team for this year’s Paris Olympics.  Travel has been an integral part of Henry’s life from a young age One of his earliest memories of travelling abroad was when he was playing with the French national team.  I must have been around 16 years old at the time and I remember being really excited to represent my country Then my career took me to Monaco and Italy when I was about the same age,” he says Henry has recently teamed up with luxury Parisian luggage house Kabuto to co-design a collection of smart suitcases for savvy travellers “I don’t travel without a hoodie because my neck is my soft spot and the air conditioning on planes blasts my neck” As someone who has travel firmly rooted in his DNA designing a luggage collection was a natural career move “Iʼve travelled to countless destinations over three decades but never managed to find suitcases that tick all the boxes So being able to create this collection with Kabuto The Kabuto x Thierry Henry Carry-on case can increase in volume by 50 per cent with a “simple zip and click” and the Kabuto x Thierry Henry Trunk transforms into a vertical wardrobe with foldable shelves “The way you can open and unlock the cases with your fingerprint for me is game-changing,” says Henry “The world is changing so fast and we don’t necessarily need keys anymore I also love the fact the case has a loop so if I want to hang up my suit it doesn’t crease “I like my suitcase to be packed in a certain way You never leave the same way you arrive on holiday When we travel I always end up bringing more home than we took; either things people have given us to bring home or extra things we have bought.”  and I love my trainers and T-shirts – I live in them,” he says.  I don’t travel without a hoodie because my neck is my soft spot and the air conditioning on planes blasts my neck so I need to protect it Henry has been lucky enough to explore all corners of the globe but Rio is his favourite destination Rio is always such an eye opener to me as there are very few places that have a sense of community in the way Rio does.” he’s acutely aware of how lucky his four children are to have the opportunity to travel.  “Their childhood is so different to mine,” he says “My travel consisted of visiting friends in my neighbourhood Occasionally my mum would take me into Paris and I thought it was beautiful “My kids are so funny as they think going to the Maldives is ‘alright’ I try to ensure they know it’s not normal to travel as much as they do And if there’s one thing he dislikes about travel it’s going through the security checks –  something we can all relate to “It’s annoying when you have to go through and open everything then put everything back in There might be a guy on the right trying to push you because you’re stopping him The guy in front is trying to put his shoes back on while you’re doing your thing I usually just go and find a bench somewhere.” Thierry Henry is a professional football coach, pundit, sports broadcaster and former player. Earlier this year, he partnered with Parisian luggage brand Kabuto as a shareholder and co-designer to introduce a limited edition collection featuring two new smart suitcases mykabuto.com/thierryhenry © BMI Publishing Plugged In Media Company planning new campus to the south of the French capital Interxion is reportedly planning to build a new data center campus to the south of Paris in the Essonne region of France Le Monde Informatique reports that Digital Realty subsidiary Interxion has filed an ICPE building permit with the DDE to operate a 15-hectare site in Les Ulis / Villejuste to the south of the capital city The land is at the intersection of the A10 motorway and the N118 Phase one of the development is due in the second half of 2023 Details on facility specifications weren't shared “The planned investment is just under €1 billion ($1.15bn) and we expect a lot of hyperscaler-type players, but not only that. We are also targeting businesses,” said Fabrice Coquio, president of Interxion France. Neither Digital Realty nor Interxion have made official announcements yet, but a spokesperson reportedly confirmed the news to DC Mag France Coquio also said a program has also been initiated with Total to gradually replace the diesel used in its emergency diesel generators with HVO fuel (hydrotreated vegetable oil), something Kao Data in the UK has already begun Last month Interxion opened its latest Parisian data center, PAR12 Data Centre Dynamics Ltd (DCD), 32-38 Saffron Hill, London, EC1N 8FH Email. [email protected]DCD is a subsidiary of InfraXmedia The French tech company for PEM electrolysis Elogen has taken a key step in the massification of its production as a key player in the green hydrogen sector in France and Europe Following its acquisition by GTT in October 2020 Elogen says it has taken a key step in the massification of its production the construction of a new stack assembly line at the Les Ulis site (Paris region) will boost Elogen’s production capacity to 160 stacks per year This will make it the largest production capacity in France GTT develops systems dedicated to the use of LNG as fuel The group is also active in hydrogen through its subsidiary Elogen which designs and assembles electrolysers notably for the production of green hydrogen This move is supported by the French government through the territorial component of its industrial revival plan The classification is also helped by partnerships with the Ile-de-France Regional Council and Bpifrance Elogen has been working on a Gigafactory project for several months with the aim of producing high-capacity stacks from 2025 The Gigafactory project is one of the 15 projects that the French government submitted to the European Commission as part of the IPCEI on Hydrogen After an initial design phase for the future stack production line Elogen is currently finalising the choice of site in France Elogen’s objective is to commercialise at least 400 MW of electrolysis capacity per year by 2030 This capacity could reach more than 1 GW if the Gigafactory project is selected as part of the IPCEI Elogen is focusing its R&D efforts in order to optimise the efficiency of its electrolysers: the GTT Group has invested nearly €15 million ($16.9 million) in the development of Elogen GTT will continue to build it to make it a flagship of the French and European hydrogen sector Elogen is now a key player in the green hydrogen sector in France and Europe Elogen is entering a new phase of its development with a first industrial ramp-up with the ambition of developing ever more efficient and high-performance PEM electrolysers aims to develop a differentiating French technology and to reduce the cost of producing carbon-free hydrogen.” added: “Elogen kicks off 2022 with the largest electrolyser production capacity in France With over 15 years of expertise in the development of PEM electrolysers leading academic partnerships and a diversified French and European ecosystem these assets enabled Elogen to win the trust of prestigious clients through innovative and defining projects for the hydrogen value chain.” Daily news and in-depth stories in your inbox The Pioneers of Offshore Engineering GustoMSC part of NOV’s Marine and Construction business is recognized for providing advanced design & engineering consultancy for mobile offshore units and reliable equipment and technical knowledge into realistic & innovative ideas The performance of new and existing jack-ups About us | Advertise with us | Contact us Plasma-derived therapies and medicines provide life-changing treatments for patients around the world who suffer from serious diseases that affect the immune system or result from non-functioning proteins in blood plasma Executive Vice President Production at LFB describes the complex and highly regulated manufacturing process of these unique biological medicines Plasma-derived medicinal products have been used for many years in immunology haemostasis and intensive care to treat rare genetic and – in many cases – life-threatening diseases or conditions These include over 80 recognised Primary Immunodeficiency Diseases bleeding disorders such as haemophilia and von Willebrand disease and other genetic disorders relating to missing or non-functioning proteins typically found in blood plasma Although they affect a relatively small percentage of the population There has been recent interest in convalescent plasma for the treatment of COVID-19 focused on the potential benefits of antibodies from recovering patients everyday therapies require the processing of healthy donors’ blood plasma to isolate and purify functioning proteins and immunoglobulins primary immunodeficiency may be treated with immunoglobulin that replaces missing IgG serotype antibodies von Willebrand disease and rarer bleeding disorders require replacement coagulation factors Patients generally require regular infusions or injections throughout their lives ranging from twice a week to once a month for a primary immunodeficiency allowing patients to live a relatively normal life or significantly extending life expectancy therapies derived from plasma play an important role in pre-natal and intensive care Plasma-derived medicinal products are used to treat patients in critical situations with serious deficiencies of essential proteins including severe haemorrhage Processing blood plasma requires a very specialised skillset and a mastery of advanced bioproduction techniques filtration and purification are required to isolate and extract some specific proteins coagulation factors or immunoglobulins required for each therapy Every pharmaceutical company employs its own proprietary procedures detergent treatment and other purification steps The biological nature of plasma demands specific storage and handling requirements as well as stringent testing to ensure safety” Manufacture takes place within a strict pharmaceutical framework defined and inspected by regulatory authorities Stringent and well‑established safety processes are also required to eliminate or inactivate pathogens at every stage Such high standards of purification are an ongoing challenge for specialist plasma technicians The result is a production timeline of between six and twelve months which may come as a surprise to colleagues working with chemical pharmaceuticals and more conventional biologics There are relatively few facilities in the world with these capabilities and consequently staff must often be trained from the ground up Plasma protein therapies are sole-source biologic products plasma-derived therapies rely on human blood which might be either remunerated or non-remunerated depending on the legislation in each country The biological nature of plasma demands specific storage and handling requirements as well as stringent testing to ensure safety so plasma supply and manufacturing costs are a significant proportion of the end cost of the product Source plasma is received in bags or bottles and each is individually tested before entering the manufacturing process Every bag is tracked so manufacturers know exactly which bag is in each end product These are transported in temperature‑controlled frozen containers to arrive at a fractionation facility where the process of testing and purification for plasma-derived products can begin Fractionation was first developed during World War II for the treatment of soldiers suffering shock and burns ethanol and temperature controls to precipitate plasma into five fractions Today’s biochemical and physical processes for base fractionation build on these methods to produce a more sophisticated range of intermediate products specialises in the upstream processing of plasma-derived medicinal products from plasma reception to intermediate product plasma is pooled and put through another rigorous testing process specialises in the downstream process from intermediate product to drug product The first stage is a slow thawing and centrifugation resulting in a liquid cryosupernatant and a cryoprecipitate paste The cryoprecipitate is rich in factor VIII (a blood-clotting protein used to treat haemophilia A) and von Willebrand factor (a blood glycoprotein involved in haemostasis) The cryosupernatant contains all other proteins (potentially other active pharmaceutical ingredients) The fractionation principle is based on the selective precipitation of proteins and adsorption on chromatographic gels for purification All products are purified through a combination of manufacturing steps such as chromatography viral inactivation steps including solvent/detergent treatment pasteurisation and nanofiltration – the latter being a process step first pioneered by LFB in 1995 The main extracted plasma proteins are albumin and immunoglobulins They are separated with a press filter after alcoholic precipitation Albumin is the most common protein in plasma by weight It remains liquid during the complete process of purification till bulk product: cold ethanol precipitations The immunoglobulin manufacturing processes combine several steps: cold ethanol and/or caprylic acid precipitation viral inactivation steps like solvent/detergent treatment and nanofiltration a glycoprotein complex made in the liver that aids both blood circulation and clotting) is firstly purified with cold ethanol precipitation followed by many steps of purification Cryoprecipitate itself is widely used by hospitals in some countries but as an unlicensed plasma component it does not offer the same safety profile as the purified protein.1 Absorption can be used to extract coagulation factors like Factor IX All these manufacturing steps are implemented in totally controlled environments LFB diagrams showing journey from plasma to product Formulation is adapted to a liquid or freeze-dried form Most plasma-derived medicinal products have room temperature stability Fill and finish are operated in LFB’s plant in Lille Bulk products are filled mainly in vials in an aseptic area freeze-dried into powder and aseptically sealed in a highly controlled clean environment then labelled and packaged in accordance with regulations Packaging for LFB’s liquid products is carried out at the site at Carvin and from there medicines are distributed to hospitals around the world the plasma-derived medicinal product traceability is vital throughout the entire supply chain from collection to patient so the latest digital techniques are employed for accurate labelling and tracking When a freeze-dried product is supplied with its solvent reconstitution is carried out at the point of treatment Despite the relative rarity of the genetic disorders usually treated by plasma-derived medicinal products global demand for some of these therapies has been rising steadily due to improving diagnosis rates broader indications and higher standards of care in emerging markets Alongside the pressure to scale up production is a global need to address the climate crisis by achieving greater efficiency and sustainability A 3D render of the new facility being built in Arras At LFB we are addressing these issues through the construction of a major new industrial site at Arras which will merge together all of the production steps for immunoglobulins It has been designed for energy efficiency and with high environmental standards for waste With 2.3 million litres of plasma fractionation capacity this will triple our current capacity to meet growing global demand for these products and greatly expedite manufacture of these vital therapies for patients that rely on them around the world much research is also taking place to explore and develop innovative recombinant medicines even if we produce relatively small amounts of a targeted protein the manufacturing process development remains time-consuming and requires expensive and complex bioreactor equipment and facilities is that it does not depend on plasma collection LFB’s rPRO™ platform in Massachusetts uses recombinant technology to express human proteins in milk that can then be purified for use in medicine using the same high pharmaceutical standards that are applied to human plasma therapies while ensuring consistently high levels of purity Such technology has the potential to greatly increase production worldwide with the prospect of improved access for millions of patients with previously unmet medical needs She is responsible of the industrial activities for plasma-derived drugs and biomanufacturing with the construction of the new industrial site in Arras Carole graduated from the University of Pharmacy (Tours) She has over 30 years of experience in production on most pharmaceutical forms as well as in Contract Manufacturing Organisations (Skye Pharma She has managed several major projects during her career: industrial IT projects site integration in a contractor culture and the start-up of a new vaccine site Carole was Executive Vice President of Delpharm , , , By No comments yet All subscriptions include online membership giving you access to the journal and exclusive content By Comment *document.getElementById("comment").setAttribute( "id" "afc5a488a5279a88433c2a48bc42af4c" );document.getElementById("a9d92917df").setAttribute( "id" Write for us | Advertise with us European Pharmaceutical Review is published by: Russell Publishing Ltd.Court LodgeHogtrough HillBrasted © Russell Publishing Limited Website development by e-Motive Media Limited Necessary cookies are absolutely essential for the website to function properly This category only includes cookies that ensures basic functionalities and security features of the website These cookies do not store any personal information CookieDescriptioncookielawinfo-checkbox-advertising-targetingThe cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Advertising & Targeting".cookielawinfo-checkbox-analyticsThis cookie is set by GDPR Cookie Consent WordPress Plugin The cookie is used to remember the user consent for the cookies under the category "Analytics".cookielawinfo-checkbox-necessaryThis cookie is set by GDPR Cookie Consent plugin The cookie is used to store the user consent for the cookies in the category "Necessary".cookielawinfo-checkbox-performanceThis cookie is set by GDPR Cookie Consent WordPress Plugin The cookie is used to remember the user consent for the cookies under the category "Performance".PHPSESSIDThis cookie is native to PHP applications The cookie is used to store and identify a users' unique session ID for the purpose of managing user session on the website The cookie is a session cookies and is deleted when all the browser windows are closed.viewed_cookie_policyThe cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies It does not store any personal data.zmember_loggedThis session cookie is served by our membership/subscription system and controls whether you are able to see content which is only available to logged in users Thierry Henry honed his skills on the hard surfaces beneath the high-rise tower blocks of his hometown Les Ulis Wenger's forgotten how to win, Pep's still learning The urban centre of his upbringing offered no sprawling fields of green upon which to show off his searing pace with the old kick-and-run that could so easily have seen him race away from any would-be marker Henry would grow up on the solid cement and skin-scraping AstroTurf in reduced spaces which demanded he learn to manipulate it more intricately it was clear to see he had that little bit more than his contemporaries “The moment my father took me in his arms at the hospital he said ‘This boy will be a star footballer’,” Henry later recalled It proved more than just patriarchal pride Henry was plucked from his town of some 26,000 inhabitants and whisked away to the illustrious Clairefontaine academy "We made Thierry start at the age of 17 and he became the exceptional football player that we all know and the person he is today,” Wenger told the official Arsenal website and the teenager quickly found himself on the wrong end of a few dressing downs from some of the more illustrious senior pros including the great Brazil striker Sonny Anderson 'Next time I come on I have to do something create some danger,” Henry told beIN Sports 'Oh isn't this nice to play a bit of football'." a flying winger who had yet to develop his insatiable appetite for goals It took him eight months to find the net in Ligue 1 for the first time my power – whatever – then I saw the goalkeeper and thought Then before you know it the goalkeeper's got the ball.” He was still some way from the record goalscorer he would later become named Ligue 1 Young Player of the Year in 1996 the following season Henry became more decisive hitting nine goals as Monaco claimed the Ligue 1 title The potential was there for all to see and he caught the attention of France coach Aime Jacquet who made a late decision to include some of the nation’s youngest stars in his squad for a home World Cup Henry finished the tournament as France’s top scorer as Les Bleus Europe’s biggest clubs came calling and Henry headed for Italy joining up with Zinedine Zidane at Juventus having hit just 28 goals in 141 matches for Monaco as he struggled to break into a side littered with attacking talent But then came familiar face who would transform his career was looking for a striker to complement Dennis Bergkamp He travelled to see Henry play in a UEFA Cup qualifier and was surprised to see the France international being used as a left wing-back Chelsea are the Christmas No.1 and look simply unstoppable Wenger accompanied Henry on a journey back to Paris that night and told him he wanted him to come to Arsenal as a centre-forward He hit 26 goals in his first season in London and would go on to become a Premier League legend racking up a phenomenal 175 goals in England’s top flight including the famous ‘invincible’ 2003-04 season when the Gunners went the entire campaign unbeaten the UEFA Champions League was the only title to evade him and he remedied that by joining Barcelona after eight years in England It may have been a relatively slow start for the boy from Les Ulis but Henry wasted little time cementing his status as a concrete Ligue 1 legend By commenting, you agree to the Prohibited Content Policy By continuing you agree to our Privacy Policy & 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Stay on current site or go to US version PARIS -- Four grey Renault 13-seater vans stand parked outside the tiny main stand at Les Ulis a semi-professional team with a thriving youth set-up 24km southwest of Paris "Thank Manchester United for them," Tshimen Buhanga Patrice Evra's best friend and the coach of Les Ulis' under-13 teams "Anthony Martial started here and we received some money when Anthony moved from Monaco to Manchester." So that's where some of the £50 million went -- it certainly wasn't down the drain laughing at those who wrote him off so soon Signed shirts from former Les Ulis players adorn the wall of the modern club house: Thierry Henry Sega Keita and many more lesser-known current professional footballers Arsene Wenger reckoned that only Sao Paulo produced more professional footballers than Paris which has only half the Brazilian city's population Paris is surrounded by social housing projects that breed brilliant footballers Kingsley Coman -- they all grew up around Paris whose two goals for Sevilla knocked United out of the Champions League last week by Andy Mitten. Anthony Martial (top row by Andy Mitten.Several of those players spent their formative years in Les Ulis an isolated project of mid-20th Century tower blocks where thousands of immigrant families from Africa and Arabia arrived in the '50s A walk around these blocks with Tshimen is an eye-opener young boys who could look intimidating approach the 36-year-old They're polite and the respect is clear for this pillar of the community the football coach -- one with proper qualifications displayed on the door of the clubhouse "You start to live football here when you are in the womb," says Tshimen as we walk across playgrounds full of kids playing football There's a mother in a hijab acting as a goalkeeper there's the brother of Porto's Moussa Marega with his son playing on a football pitch paid for by Thierry Henry "The kids here are always outside playing football coaches like me who care about them as people and about their schooling A large poster hangs in the clubhouse advocating that the young boys eat well have their kit well organised and brush their teeth twice a day photos of former players who have gone on to success -- the grinning Henry in an oversized Nike jumper Tshimen Buhanga is responsible for nurturing an astonishing array of talent at Les Ulis. Tshimen Buhanga at Les Ulis who is also featured on a framed cover of France's leading daily L'Equipe in the clubhouse also started on a tiny grass pitch outside his tower block There are places to play football everywhere -- even the trees in the school playground have been spaced apart so that they can make goalposts "Martial is from a family of good footballers," Tshimen points to a signed shirt of Anthony's older brother "Les Ulis we have right in front of our youngsters' eyes the perfect examples of all the boys who have become professionals I gave Martial some of Patrice's boots to wear when he was 12 the key is that they stay grounded and humble." We go into the shopping centre among the tower blocks where one of Evra's many brothers once worked and gave him leftover food at the end of the day another of Evra's gang of scallywags who stayed a close knit group of friends throughout their childhood but several stayed on to become leading lights in the community Mohamadou is now the coach of Les Ulis' first team in France's fifth division There doesn't seem to be a male who doesn't know him who doesn't approach with a polite "ca va?" and a handshake It's great to see football coaches as respected pillars of the community detailing the club's proud history in developing youngsters. Les Ulis training room by Andy Mitten."He was very talented," he recalls "We put him into more advanced groups and we could see his determination to be a footballer from the age of 12 because he worked so hard He was fast -- and he was always desperate to win He's from a good family and he had a good education Martial visited Manchester City at 12 and left Les Ulis to live in Lyon at 14 Football gives the boys a focus outside school The ones this writer chatted with on Wednesday claimed to support Barcelona Real Madrid and Manchester United (because of Evra and Martial) but going to PSG matches is another world -- the stadium set amid the wealthy arrondissements of the French capital has long been alien to the culture of boys from Les Ulis Evra to Italy after being missed not only by the Clairefontaine The rejections made him more determined to make it as a footballer -- determination is not lacking among the often underprivileged inhabitants of the drab concrete towers of Les Ulis Paris and its surrounding areas is a hotbed for young French players. Nick Potts/PA Images via Getty ImagesRachid Khlifi a coach and scout mostly based in and around Paris most recently as the head of scouting at the Paris FC academy pinpoints several significant factors which make Les Ulis and other areas like it a breeding ground for talent "Youth football is very well organised around Paris and the standards are very high even those coaching the 6-year-olds -- they all have proper coaching qualifications but the clubs have agreements with the schools for two more training sessions They're playing structured football every day -- and they're playing street football when they finish "These areas are a real melting pot of people You have people from all over the world -- French people coming to Paris for a job black people coming from the old French colonies like Mali or Senegal In the '90s you had people from Congo and Zaire with roots in North Africa -- Morocco or Tunisia This mix produces every type of footballer You can have big physical players that can do well in England "A lot of immigrants and sons of immigrants dream of being professional footballers That makes players with a strong mentality -- and there are lots of very good youth teams for them to play for -- it's just sad that there's not a lot of money beyond youth football France only woke up to football in 1998 after winning the World Cup so there hasn't been that traditional of families following clubs for decades that you have in England." the second team in Paris and doing well in France's second tier But they never forget where they've come from and what they learned there shapes them for life Thierry Henry has opened up on the Diary of a CEO podcast about how his early childhood experiences might have played a key role in transforming him into the star that he later became but left him unequipped to deal with life outside of the sport Henry grew up in Les Ulis as a second-generation immigrant from the French overseas territories in the Caribbean His family had left the Caribbean for mainland France to work and find the ‘French Dream’ There was an expectation within his parents that they had to work hard as they could not let down their communities Despite being born in France, Henry was handed down those pressures that his parents had felt in moving to continental France through their expectations placed upon him. The former player and now current manager for the France under-21s spoke about how it was an experience of It was not so much about belonging to the country or to the community that he grew up in but fitting in enough that you did not disrupt the demands that came with his family’s move Henry’s father left the family home when he was young ‘My parents divorced when I was seven… eight… He was present when I had to go to training or games hugging… when I say that I’m not complaining when you grow up in this sort of neighbourhood it amplifies what’s happening at home be the man… don’t cry.’ These sorts of attitudes were built within the striker from a young age Henry describes where he grew up as a ‘normal neighbourhood… gangs his footballing talent kept him away from the more violent elements within his hometown ‘When you have a certain gift and the guys in the neighbourhood know that you might do something you are also protected He might do something… an unwritten protection because you might do it.’  Henry’s complex relationship with his father is a focus throughout the interview and a dysfunction that the player has not quite come to terms with Even now the player has an uneasy relationship with this dual concept Henry achieved everything he could have imagined as a player but there is this gnawing worry that he has not developed beyond that The first time his father held him as a baby he spoke words that have followed the striker throughout his glittering career: ‘This baby will be an amazing football player.’  The words were quite something else for the baby ‘After that you can imagine what comes next.’ Henry continues ‘I was programmed to succeed… it was always a mission I was on a mission to fulfil his dream to please him.’  Henry relates how when he was 15 he scored six goals in a victory but on the drive back home with his father he was admonished for all the things he had not done right ‘The most difficult thing for me to do as a man and as a player… was to please my dad.’ Even as he won plaudits that the athlete had developed from this childhood ‘but the human being was missing.’ Henry left his familial home to join the prestigious Clairefontaine footballing academy It was a place that fostered from the point of entry an intense sense of competition among those who would grow up around him The trials to get into the academy are notorious a crop of around 1000 young children from across the country attempt to impress their talent upon those watching the best are invited back in an ever-decreasing number until there are only 23 kids left each player was competing for their future and their friend’s futures provided a direct challenge to their own There was no ‘normal young life… what you are exposed to right from the start is very difficult to deal with.’  It is only now that Henry has begun to process the extreme and often alien conditions that he had to experience in a precocious developmental era He now looks at his children who have not grown up around the same pressures and sees something that he feels was lacking within him that was never allowed to grow for him to become the athlete he later became They are teaching me to be a dad.’ He clarifies And they’re opening doors that I did not know how to deal with.’  ‘I can see sometimes when they look at me how much they love me… if they only knew I look at them the same Thanks for being here because it would have been tough.’  Henry joined AS Monaco at the age of 17 and there the forward began a career where he became a legend of the game the invincible season with Arsenal and the Champions League win with Barcelona stand out always in memory ‘When people see my path… they go “it was always going to be” When you know the hardest thing I had to do was please my dad the rest was nothing for me.’ Everything else that came in his career was ‘so easy compared to what I had to do in order to please the old man And my young self is still waiting for that approval.’ the career of an athlete is a short affair and there comes a time when it finishes and until this point Henry had been completely unprepared for what followed ‘As an athlete as long as you stay within that frame you can feed whatever you need to feed to satisfy that other little thing that you had: your ego because you prefer to be the athlete rather than the human being.’ As the athlete the competitor dies… People don’t teach you to die So now you are going to face all your problems.’  it’s a shock to the system because you are not technically equipped to live in that world.’ From the age of five Henry had been training for this career and by the time he was 37 it was over His entire identity until this point had been constructed to be a footballer and within a night it was gone And all that he has put aside and pushed to the back of his mind in pursuit of this relentless goal returns unwillingly to the forefront His decision to stop playing was ‘easy.’ The player had spent the last ten years suffering from an Achilles problem and eventually reached a point where he could continue no longer ‘I didn’t have a problem with stopping… but I didn’t know what would happen ‘Now all I had was questions.’ There was no longer the routine of the professional game there was no structure of seasons and matches to map out a calendar and there was no direction as to what would happen next Henry looked after his retirement to become a manager to fill the void and escape the feeling deep inside ‘You pass your badge… you try to do something to make sure that you’re not going to think about what has been chasing me for a very long time.’  What was chasing him finally found him during his time managing the Vancouver Whitecaps It was here that there was a moment of pause for the first time in his life as the global pandemic hit in 2020 COVID-19 left the manager isolated with his family back home in London ‘Something like that had to happen to me for me to understand vulnerability The lockdown was an immensely difficult time for every one of us and for Henry unable to see his children for a year His feelings so long pushed back had found a way to surface Henry talks about how he was forced at this time to look inward and to consider and communicate with his inner child It was a terrifying prospect for someone who self-admits that he was ill-equipped with the tools to deal with this conversation ‘They tell you everything you didn’t want to hear… Be yourself Henry was able to return to see his children And it sparked a moment that the former World Cup winner appeared to consider the most important in his life As his time visiting his girlfriend and his children was over a return back to his working life awaited him The forward placed down his bags to hug his children goodbye to the kids… For the first time… they see me He could not bear the thought to leave his children or escape a moment where ‘for the first time Henry states in the interview that ‘throughout my career and since I was born I must have been in depression.’ Only now has man finally begun the process to heal and develop what for so long had been holding him back He appears to recognise that it is a long pathway Something he acknowledges is a strange situation for one of the best players to have ever played the game Someone who has a statue of him outside a stadium Someone who will go down in history as an ‘invincible.’ But this was never the approval that he was looking for Our approval was given too easily and too willingly It was not the expression of a son looking to his father for something never given It was not the approval of the human or the child behind the player it was only ever for what the athlete had achieved GFFN | Nick Hartland Please enable JS and disable any ad blocker One whose magic seemed to have spread throughout his body being remembered as one of the best players that has left the history of France Thierry Daniel Henry was born in the Parisian town of Les Ulis (France) a suburb where other stars of the sport such as Anthony Martial or Patrice Evra also grew up Antoine (Guadeloupe) and Maryse (Martinique) as the young Henry was not really attracted by the passion that runs through the bodies of young boys and girls At the age of seven he tried his first experience in a local club but it did not last longer than the pressure exerted by his father to attend training but after a year his father had several altercations with the club so Henry switched to ES Viry-Châtillon and played there for two years Palaiseau's American coach Jean-Marie Panza Antoine focused on helping him succeed in soccer continually taking Thierry to camps and matches where it soon became clear that the youngster was an above-average player for his age Maryse worried that her son was spending too much time on the field and not enough time studying when he needed his parents the most was when they divorced it was Monaco who knocked on his door after he scored six goals in one game Scout Arnold Catalano requested that he complete a course at the Clairefontaine Academy and despite the director's refusal to admit Henry due to his poor school results he was allowed to complete the course and joined Arsène Wenger's Monaco as a youth player He was one of the 25 selected and shared a class with players such as William Gallas Thierry Henry made his first-team debut for Monaco on 31 August 1994 in a 2-0 defeat against Nice Despite Wenger's belief that Henry could explode as a striker (something he did in his later time at Arsenal) he placed him on the left wing as a winger because he believed his pace and ball control would be more damaging against full-backs He had already begun to give hints of the talent he possessed when in 1996 he won the French Young Footballer of the Year award as well as helping his team to the league title in the 1996/97 season with nine goals in 36 games The following season was to be marked by reaching the semi-finals of the UEFA Champions League and participating in the World Cup on home soil where he recorded 28 goals in 156 appearances before making the jump to Turin His arrival at Juventus was rather short-lived with Henry admitting on Jamie Carragher's podcast that disagreements with Juve manager Luciano Moggi were the main reason for leaving the Italian club and starting the new century in London The 1999/2000 season was to be marked by the beginning of a beautiful story between Thierry Henry and Arsenal An eight-year spell in which the Frenchman played his best football at the top of the spear reuniting him with Arsène Wenger and an Arsenal where he proved to be a world-class player He came to replace an old acquaintance: Nicolas Anelka with whom he shared a class at the Clairefontaine Academy Constantly questioned because of his past in Turin and unsure of his ability to adapt to the pace of English soccer these doubts disappeared in his first year thanks to the 26 goals he scored in 47 matches Despite losing the UEFA Cup final to Galatasaray the joy was still intact after arriving and winning Euro 2000 his second consecutive title with the national team being again the top scorer with 3 goals as in the 1998 World Cup The 2000/01 campaign would be similar to the first one in terms of numbers falling again in the Premier League (2nd) with the hegemony of Manchester United These early years were the key that illustrated the point of maturation that the Frenchman was acquiring The good play and the titles at international level were coming but if there was one thing that still eluded him Two runner-up finishes and two lost finals until the 2001/02 season The reward came in the form of a Premier League and FA Cup double with a 2-0 win over Chelsea Thierry Henry became the league's top scorer but his form was not enough to win his third consecutive title with the French national team at the 2002 World Cup in Korea-Japan where the reigning champions suffered a shock elimination in the group stage The 2002/03 season was one of his best in terms of performances: 32 goals again and 28 assists that did not serve to retain his league title but did serve to retain his FA Cup title and earn him his first Player of the Year award as well as proclaiming himself the first player in the 21st century to score more than 20 goals and 20 assists in a single season in all five major leagues he set a record as no one had ever managed to achieve such a number of assists After a poor showing at the last World Cup the French national team ended up with a Confederations Cup in 2003 something he remedied in 2003 with four goals and two assists The 2003/04 season is remembered for being the best ever performance by a team in the history of English soccer It took more than a century for a team to record an unbeaten run through the domestic championship in a single season Thierry Henry had once again surpassed the natural and scored 39 goals and 18 assists as well as picking up his second Player of the Year award from the Professional Footballers' Association (PFA).He was also second again in the FIFA World Player of the Year award and won his first Golden Shoe as a professional Thierry Henry had reached his peak of form along with a series of players led by Arsène Wenger The Invincibles called themselves the Invincibles After getting through the group stage without playing their best football the team led by Zinedine Zidane lost in the quarter-finals against the future champions The bad fortune continued at club level with Henry in a 2004/05 campaign without a league title but with Diego Forlan (31 goals) and an FA Cup The highlight was that he became the first player to win back-to-back Golden Boots as those won by Ally McCoist are considered ''unofficial'' The 2005/06 season meant a lot in terms of autonomy Named Gunner captain after Vieira's departure he became Arsenal's all-time leading scorer surpassing Cliff Bastin's record of 150 goals completed the season as the league's top scorer was voted FWA Footballer of the Year for the third time in his career and was selected in the FIFA World XI for the first time but the flame of hope was eventually extinguished after reaching the 2006 UEFA Champions League Final and losing 2-1 to Barcelona Both Arsenal's inability to win the league title for two consecutive seasons and the relative inexperience of the Arsenal team caused much turmoil over Henry's future the Frenchman declared his unconditional love for the club and agreed to a four-year contract adding that he would stay at Arsenal for life In the 2006 World Cup he came close to a sweet taste when he lost in the final against Italy A final whose most outstanding action was not the penalty that gave the Azzurri victory but Zidane's header on Materazzi in his last performance at international level Henry's eighth and final campaign in London was marked by injuries After being out on several occasions during the season he returned in a Champions League match against PSV but that was when he fell again for three months that condemned him to not being able to say goodbye to his fans as he wanted The results detected a groin problem that closed the curtain on his fruitful spell in London (so far) Barça paid 24 million euros for the Frenchman's services Henry left the club of his life to avoid being an obstacle and landed in Spain with the aim of reviving from his irregular last season He debuted as a goalscorer in La Liga with a hat-trick against Levante and in European competitions against Olympique Lyon he was unable to perform at his best and at the end of his first year there was already speculation of a possible return to the Premier League The expectations of every FC Barcelona fan fell far short of what he had been offering despite his 19 goals he broke a new record and became the French player with the most goals in the history of the French national team at that time with 43 goals and surpassing Michel Platini at Euro 2008 he was again eliminated in the group stage after losing to the Netherlands and Italy If Thierry Henry is also known for breaking countless records The 2008/09 season is remembered for the perfect run by a young Pep Guardiola and his charges A unique six-team run that no team had achieved until Bayern Munich arrived last season to match that epic feat The Frenchman was part of the 2-6 with two goals against Real Madrid at the Santiago Bernabeu but in the second goal he had to leave with a knee injury after a clash with Iker Casillas which affected his participation in the final of the Copa del Rey and UEFA Champions League ended up underlining his poor adaptation and he finished with only four goals in all competitions his lowest tally since his time at Monaco and Juventus he is remembered for a handball to William Gallas that eliminated Ireland from the play-offs was a play that made reference to the goal scored by Diego Armando Maradona in the 86 World Cup against England with his hand France qualified for the World Cup in South Africa with the water on their neck and Henry confirmed his retirement after a poor participation in the World Cup stating that he had made the decision before the World Cup Thierry Henry signed for the New York Red Bulls on July 14 2010 and became the highest paid player in the league with a salary of $5.6 million he managed to help the MLS take a leap in quality David Beckham or Frank Lampard being the next to visit the aphrodisiac American league the surprise came in January 2012: Henry had a pending account in London so he was loaned for two months to the Gunners to say goodbye like the true legend he was the Frenchman scored a memorable goal against Leeds United that earned Arsenal a place in the last 32 of the FA Cup a goal in his own style that brought the Emirates Stadium to its feet it was his favorite goal for the London outfit but failed to win the conference despite registering 35 goals and 30 assists in the last three seasons He also fell just short of his first MLS Most Valuable Player award although the accolade eventually went to Chris Wondolowski he announced that he was leaving the New York club confirming his retirement as a professional footballer two weeks later at the age of 37 Patrice Evra is a French international footballer who has a net worth of $14 million Patrice Evra stands as one of modern football's most charismatic and accomplished defenders Evra's journey from humble beginnings to international soccer stardom epitomizes resilience and determination Rising through the ranks of French football his breakthrough came at AS Monaco before a successful stint at Manchester United defined his career Known for combining defensive solidity with attacking flair the French international earned 81 caps for his country while serving as captain during the 2010 World Cup and larger-than-life personality made him a fan favorite across Europe Following his illustrious eight-year tenure at Manchester United Evra enjoyed successful spells at Juventus and Marseille before retiring in 2019 after a brief stint with West Ham United His post-playing career has seen him thrive as a pundit Patrice Latyr Evra was born on May 15, 1981, in Dakar, Senegal, before his family moved to France when he was a child. Growing up in the tough Parisian suburb of Les Ulis—the same neighborhood that produced Thierry Henry—Evra faced significant hardship The youngest of 24 siblings from his father's multiple relationships working at a McDonald's and cleaning school buildings to help support his family playing for local club CO Les Ulis as a forward before joining CSF Brétigny His talent eventually caught the attention of scouts and he signed his first professional contract with lower-division Italian club Marsala in 1998 continuing to develop his skills before returning to France with Nice in 2000 where coaches converted him from a winger to a left-back—a position that would define his career Evra's breakthrough came after transferring to AS Monaco in 2002, where his performances in Ligue 1 and the UEFA Champions League showcased his exceptional abilities. His speed, technical skills, and tactical intelligence helped Monaco reach the 2004 Champions League final, where they ultimately lost to José Mourinho's Porto This European campaign established Evra as one of the continent's premier left-backs and attracted attention from elite clubs In January 2006, Sir Alex Ferguson brought Evra to Manchester United for £5.5 million—a move that would transform both the player's career and the club's defensive lineup Despite initial struggles adapting to the Premier League's intensity Evra soon became a cornerstone of United's defense forming part of a backline that dominated English football for nearly a decade Evra's eight-and-a-half seasons at Manchester United represented the pinnacle of his career he evolved into a complete modern full-back combining defensive resilience with attacking contributions and understanding with United's wingers added a vital dimension to the team's play The Frenchman collected an impressive trophy haul at Old Trafford: five Premier League titles (2007 and the crowning achievement of the 2008 Champions League victory over Chelsea in Moscow He also reached two additional Champions League finals in 2009 and 2011 Evra emerged as a vocal leader and dressing room presence eventually wearing the captain's armband on numerous occasions His passion for the club and fierce competitiveness particularly in derby matches against Liverpool and Manchester City Evra's international career with France spanned 11 years and included 81 caps between 2004 and 2015 He represented Les Bleus at three World Cups (2010 2014) and two European Championships (2008 became a national scandal in France and led to Evra's temporary suspension from the national team Evra eventually returned to the French setup under Laurent Blanc and Didier Deschamps continuing to represent his country until 2016 Evra secured increasingly lucrative contracts that reflected his status as an elite defender His initial transfer to Manchester United in 2006 came with a reported weekly salary of around £25,000 which more than tripled over his time at the club reliable sources indicated Evra was earning approximately £85,000-£90,000 per week His 2014 move to Juventus came with a two-year contract worth a reported €3.5 million per season (approximately £55,000 weekly) Despite taking a pay cut from his Manchester United wages the deal included performance bonuses and a third-year option that Juventus eventually triggered Evra's brief stint at Marseille in 2017 reportedly earned him around €50,000 weekly though this arrangement ended prematurely following an incident with a fan His final professional contract at West Ham United in 2018 was a short-term deal worth approximately £75,000 per week for the remainder of the 2017-18 season Evra supplemented his club earnings with endorsement deals which further enhanced his financial portfolio Industry estimates suggest his career earnings from contracts and endorsements exceed £30 million enabling substantial investments in real estate and business ventures following his retirement Evra has reinvented himself as an engaging television pundit and social media personality and catchphrase "I love this game!" have made him a popular figure on platforms like Instagram where he shares motivational content mixed with humor Evra has also pursued coaching qualifications and spoken openly about his ambitions to manage at the highest level he began working on his UEFA coaching badges while occasionally returning to Manchester United's Carrington training ground to observe sessions Evra has become an advocate against racism in soccer drawing from his own experiences to speak out on discrimination issues "I Love This Game," detailed both his professional triumphs and the personal challenges he overcame including childhood sexual abuse—a revelation that highlighted his courage in addressing difficult topics © 2025 Celebrity Net Worth / All Rights Reserved