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Excavations conducted by theInstitut national de recherches archéologiques préventives (Inrap) at Onnaing
have uncovered a remarkably large rural site inhabited between the end of theBronze Age and the beginning of theIron Age
The high concentration of remains and the richness of the discoveries offer a picture of Protohistory in northern France
Research has revealed a settlement spanning several centuries
The continuity is evidenced by a remarkable concentration of structures and artifacts over an area of more than three hectares
Never before has such an extensive site been unearthed in the Hauts-de-France region.Among the remains identified
Some present a rectangular plan that can reach 25 meters in length
Similar dimensions suggest constructions intended for collective or specialized activities
more modest structures have been found scattered in the surroundings
testifying to secondary settlements related to daily life and craft activities
The presence of large pits and hearths indicate that the site was a center of numerous activities
Archaeologists have found evidence of spinning and weaving
Among the most unusual discoveries is an exceptionally preserved wooden chest dating back to the early Iron Age
suggest a specific use that is still unknown
The contents of the artifact remain obscure
but its excellent state of preservation opens new perspectives for the study of storage practices or possible rituals related to that period
Archaeologists have identified several burning structures
some of which are of particular interest because of their shape and arrangement
including baked clay blocks and traces of charcoal
rectangular and more elongated (0.8 meters by 3 meters on average)
are found systematically along the walls of the buildings
An additional type of hearth was found in a large repurposed silo
well-fired soil suggests intense thermal activity
Ongoing analyses and experiments will help clarify their use
The importance of the discovery goes beyond the local context
The concentration of structures and their organization suggest that this settlement may have played a central role within a larger network of settlements
Other excavations conducted in the region had already revealed the presence of protohistoric villages
but never with such a density of structures
It remains to be understood what the precise role of the site was: was it a center of production and exchange
Or of a village with a particular social status
The new discoveries enrich our knowledge of protohistoric societies in northern France
LBV Magazine English Edition
archaeologists have discovered a massive village inhabited between the Late Bronze Age and the beginning of the Iron Age
features a high concentration of buildings
making it an exceptional site within the archaeological landscape of northern France
Excavations have revealed more than twenty buildings
with rectangular designs up to 25 meters in length and apse-like finishes
along with other smaller buildings scattered throughout the area
suggests a well-defined spatial organization and differentiation in land use
This configuration indicates that the settlement may have played a central role within a broader network of human occupations in the region
The study of numerous pits found at the site has provided valuable information about the daily practices of its inhabitants
Traces related to activities such as spinning and weaving
food storage and processing have been identified
Notable among the findings are ceramic fragments discovered in the fill of some of these structures
which have allowed researchers to reconstruct aspects of daily life in this prehistoric community
One of the most surprising discoveries is an exceptionally well-preserved wooden box
This 45 cm-sided structure features a unique assembly with few metal elements and walls made of vertical planks
Despite its remarkable state of preservation
the exact function of this object remains a mystery to archaeologists
who continue to investigate its potential use and original contents
One of the most striking aspects of the excavation has been the identification of various combustion structures
whose design and location have raised intriguing questions about their function and technology
with diameters exceeding a meter and fills composed of materials exposed to high temperatures
such as reddened clay blocks and carbonaceous layers
larger rectangular combustion structures have been identified
systematically arranged along the walls of the buildings
These findings are complemented by a large circular model
excavated in an ancient silo and equipped with a thick refractory base
suggesting exposure to intense and sustained heat
archaeologists are considering several hypotheses regarding their potential use
which could be related to food cooking or ceramic production
The discovery of this settlement not only expands our knowledge of the distribution and organization of prehistoric communities in Hauts-de-France
but also raises new questions about the role it may have played in its time
The remarkable concentration of structures and artifacts within a relatively confined area suggests that the site may have been a key point within a network of interconnected settlements
Excavations in Onnaing have provided crucial data for reconstructing life in the Protohistory of northern France
complementing other archaeological evidence from the region
With ongoing analysis of the recovered materials and future research
experts hope to uncover more details about the social
and technological dynamics of these ancient communities
Institut National de Recherches Archéologiques Préventives (INRAP)
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Orano Med’s ATLab Laboratory in Onnaing will begin producing lead-212-based radiotherapy by 2025
will build a new Alpha Therapy Laboratory (ATLab) in Onnaing
It will be the first industrial-scale pharmaceutical manufacturing facility in Europe dedicated to producing the lead-212 radioligand therapies known as targeted alpha therapies (TAT)
The facility will focus on manufacturing lead-212 therapies developed by Orano Med and distributing them across Europe
The project is aligned with France’s biotherapy-bioproduction acceleration strategy
focusing on the development and production of new biotherapies
Orano Med’s combined production capabilities
including the ATLab Laboratory in Onnaing and another similar upcoming facility in Indianapolis
are projected to yield 10,000 doses per year by 2025
Construction of the ATLab commenced with a ground-breaking ceremony in February 2024
The facility is expected to create 25 direct jobs with the production phase to begin in 2025
The new ATLab will be situated in Valenciennes
The ATLab Valenciennes will benefit from the industrial network of the Valenciennes metropolitan area and the Hauts-de-France region
Its proximity to Brussels and Roissy-Charles De Gaulle (Paris) international airports is one of the key factors in the selection of the location
The ATLab Valenciennes will cover a total area of more than 3,000m² (32,292ft²) and produce new targeted lead-212 alpha therapies for cancer patients on a large scale
A modular design will be used for production lines, enabling the addition of more lines in the future. The flexibility will allow for the manufacture and distribution of multiple drugs simultaneously
potentially increasing efficiency and scalability in pharmaceutical production
The facility will initially produce 5,000 patient doses a year
with plans to expand the output tenfold by the end of the decade
The initial dose is planned for release in mid-2025
The ATLab Valenciennes is being developed with a €29m ($31m) investment
The project is supported by the Hauts de France region and the Valenciennes metropolitan area
It is also a recipient of the Industrialisation and Health Capacities 2030 call for projects
making it eligible for public aid of €3.8m ($4.1m) from a total investment of €29m
Lead-212, an alpha-emitting radioisotope from the thorium-232 decay chain, is exceptionally rare and potent as a therapeutic payload against cancer cells. Orano Med leverages its expertise in advanced nuclear technologies to extract and purify lead-212, using it in several promising targeted cancer treatments known as TAT
TAT utilises lead-212 in conjugation with diverse biological molecules
to effectively target and destroy cancer cells
The approach allows TAT to selectively identify and eliminate cancer cells
Orano Med has pioneered a process for large-scale
cost-effective production of high-purity 212Pb (lead-212) using thorium-232
the company is well-equipped to meet the global demand for TAT
The patented chemical process involves multiple extraction and purification stages to isolate lead-212 from thorium-232 descendants
Orano Med’s production and drug chain is fully integrated and independent of external radionuclide suppliers
installation and maintenance services provider based in France
is associated with the construction works of the project and is responsible for all the technical operations
laboratory equipment and pneumatic transport
is a clinical-stage biotechnology company specialising in developing targeted cancer therapies using lead-212
The company employs 110 people across France and the US and has 12 patented innovations
It has two current ongoing clinical trials
two preclinical laboratories for alpha treatment development and one global industrial platform for lead-212 manufacturing
Given lead-212’s short half-life of 10.6 hours
the therapies require production close to hospitals
necessitating the construction of additional ATLabs to meet global patient needs
Additional ATLabs are also planned to meet global demands
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Toyota Motor Europe celebrated yesterday 5 million vehicles production at its Valenciennes plant in northern France
designed by Toyota Europe Design Development (ED²) was revealed
is painted in the French tricolour to mark the occasion
The celebration was attended by 200 guests
including the French Minister Delegate for Industry
The milestone marks a real feat with an impressive production volume reached in less than 24 years
It is the fruit of the hard work and passion of our teams and also all our partners
and stakeholders including local and national French authorities
It demonstrates our ongoing commitment to meet the European market’s expectations with the quality the Toyota brand is known for
TMMF started production of the Toyota Yaris in January 2001 with an initial annual production capacity of 150,000 units
The Yaris became the most produced single model in France seven times over 10 years
the Yaris Cross has quickly established its strong position in the fast-growing European B-SUV market
and was the most produced single model in France in 2022 and 2023
The Yaris Cross now leads the European B-SUV segment and is Toyota’s top-selling model
with sales of 173,209 units in the first 10 months of 2024
the Valenciennes plant produced 273,788 units of both Yaris Cross and Yaris
the largest output amongst Toyota’s five vehicle assembly facitilies across Europe
5,000 employees produce more than 1,200 Yaris Cross and Yaris vehicles every day
Toyota has made a total cumulative investment of 1.6 billion euros in TMMF’s facilities
including the capital investments for each new generation and model
as well as significant resources for continuously improving the manufacturing operation’s environmental performance
Toyota believes that when people are free to move
inclusive and sustainable mobility to achieve its mission of producing “Happiness for All”
TME launched the KINTO mobility brand which offers a range of mobility services in 20 countries
and is growing its business-to-business sales of zero-emission fuel cell products and engineering support
Contributing to the UN Sustainable Development Goals
Toyota is working to achieve carbon neutrality in its entire business across Europe
A historic leader in CO2 reduction in Europe
TME aims to achieve 100% CO2 reduction in all new vehicles in Western Europe by 2035 and will continue to offer a full range of electrified powertrains to customers across the region with its hybrid
Orano Med (a subsidiary of the Orano Group) has laid the foundation stone for its ATLab (Alpha Therapy Laboratory) in Onnaing
This will be Europe's first industrial-scale pharmaceutical facility dedicated to the production of lead-212 (Pb-212) based radioligand therapies
This will be Europe’s first industrial-scale pharmaceutical facility dedicated to the production of lead-212 (Pb-212) based radioligand therapies
Targeted Alpha Therapy with lead-212 combines the natural ability of biological molecules to target cancer cells with the short-range cell-killing capabilities of lead-212 generated alpha emissions
Development of these therapies has been held back by the lack of facilities to manufacture on an industrial scale
Orano Med’s ATLab Valenciennes will help to make these new treatments more readily available
with over 3,000 square metres of floor space will focus on the production of lead-212 therapies developed by Orano Med and their distribution in Europe
Orano Med also plans to inaugurate a similar facility later this year in Indianapolis to serve the US market
This combined capacity will enable Orano Med to manufacture 10,000 doses a year by 2025
with the aim of producing ten times more by the end of the decade
Given the short half-life of lead-212 (10.6 hours)
the drugs need to be produced close to hospitals
The construction of further ATLabs is therefore envisaged to meet patients’ needs worldwide
Orano Group’s Senior Executive Vice-President Projects & Innovation R&D & Nuclear Medicine
commented: “The ATLab in Onnaing is a very important step in our development strategy …
The expansion of our production capacity in the radiopharmaceutical field is part of a drive to revitalise our country’s industrial and economic fabric.”
The construction of ATLab Valenciennes is supported by the Hauts de France region and the Valenciennes metropolitan area
The project has also been selected under the France 2030 plan following the call for “Industrialisation and health capacities 2030″ projects and will receive public support of almost €3.8m
Orano Med CEO Julien Dodet is convinced that radioligand therapies will soon become an essential tool in the fight against cancer
“As the Phase II clinical trial of our most advanced drug AlphaMedix nears completion
we are building a global industrial platform to ensure the large-scale production and distribution of these potential treatments.”
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A Yaris automobile sits on the production line at Toyota's automobile manufacturing plant in Onnaing
Photographer: Pascal Rossignol/AFP via Getty Images
marking the first vehicle plant reopening in the country where the coronavirus pandemic shut most industrial sites last month and some unions have vehemently opposed the return of workers to assembly lines
The Japanese carmaker will restart at Onnaing
where the Yaris model is assembled for the European market
A decision taken last week calls for a gradual return to a single shift each day with adjusted working hours
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Bringing self-charging full hybrid powertrain technology to the Mazda model range
the Mazda2 Hybrid[1] is the outcome of a long-standing collaboration between Mazda Motor Corporation and Toyota Motor Corporation
The two companies entered a long term partnership in 2015
Since then they jointly develop technologies for electric vehicles
collaborated on advanced safety technologies
hybrid vehicle for the European market started on the 15th of January 2024 in Onnaing
The self-charging Mazda2 Hybrid is the perfect car for city life: with its expressive lines
it feels right at home in an urban setting – and is ready for any outer-city adventure
The newly introduced Mazda signature design elements express a sleek and sophisticated look
The 2024 Mazda2 Hybrid has received a new face with a true to Mazda bumper and grill design
Together with a unique rear – designed in the European Design Studio and featuring a liftgate garnish in body-colour – the setup creates a sporty look and gives the vehicle a mellow but expressive surface to showcase the craftsperson’s skill
the new Mazda2 Hybrid conveys a sense of vitality while keeping a simple stability and firmness at its core
Offering a platform with exceptionally high torsional rigidity
low centre of gravity and ideal weight distribution for reduced body roll the car is fun to drive
stable and also has a very short stopping distance
MacPhercon strut front and torsion beam rear suspension combines excellent ride comfort with enhanced agility
Vibration and Harshness) levels are notably low and offer the occupants a quiet
The Mazda2 Hybrid features cutting-edge intelligent hybrid technology which seamlessly transitions between electric
giving the driver an agile and enjoyable driving experience in any situation
92 PS/68 kW three-cylinder petrol engine with a 59 kW electric motor for a total system power of 116 PS/85 kW
The 2024 hybrid accelerates from 0-100 km/h in 9.7 seconds and has a top speed of 175 km/h
It returns WLTP combined cycle fuel economy of only 4.2-3.8 l/100 km and CO2 emissions of just 97-87 g/km (wheel size-dependent)
The company is convinced that by offering a full range of sustainable technologies – ranging from battery-electric vehicles
to using a rotary engine as a power generator – a multi-solution strategy is an efficient and effective way to reduce emissions
Mazda will meet the European CO2 emission targets through to 2030 and beyond
Mazda will further accelerate the electrification of its model range under the multisolution approach: by 2030 the company will be offering a full range of electric vehicles for the most important segments of Europe
Mazda aims to achieve carbon neutrality in all its operations (including product
[1] WLTP fuel consumption (combined): 4.2-3.8 l/100 km; CO2 emissions (combined): 97-87 g/km