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in the heart of the Vallée de la chimie [Chemical Valley]
Arkema’s Pierre-Bénite platform comprises a manufacturing site
the Centre de recherche Rhône-Alpes (CRRA)
a genuine shared services center for the Group
the facility is one of Arkema’s major employment hubs in France
competitiveness and ecological transition issues and challenges
Arkema is engaged in an ambitious transformation of this site to address growing demand for new materials
in particular for current and future generations of Lithium-ion batteries
With its 400-strong workforce, the Pierre-Bénite manufacturing plant specializes in the production of fluorochemicals. It produces Forane® fluorogases as well as the Kynar® polyvinylidene fluoride (PVDF) specialty polymer
The plant’s products are used in a number of sectors: construction
the Pierre-Bénite plant meets the requirements of safety regulations by carrying out hazard studies
and conducting regular exercises with internal teams and external response teams
In order to constantly improve working conditions and ensure everyone’s safety, the Pierre-Bénite plant has an integrated management reference system (Arkema Integrated Management System)
Kynar® PVDF manufactured in Pierre-Bénite is the benchmark material in the semi-conductor market earmarked for microprocessors in ever growing demand
The Pierre-Bénite facility is the only Arkema site among Arkema’s three PVDF production sites in the world to produce the high performance grades required for this market
A benchmark polymer material in the Lithium-ion battery technology
Kynar® PVDF has been renowned and enjoying a leading position in this buoyant market for over 10 years
It is used by all major battery manufacturers in Asia and the US
and is currently being certified by European “pure players” that have emerged following the advent of the European “Gigafactories” ecosystem
The emulsion polymerization and copolymerization technology developed in Pierre-Bénite has enabled Arkema to gain a strong position in this market and a foothold in each of the market’s segments (electronics
In recent years Arkema has also conducted significant research work in the field of Foranext® fluorinated lithium salts
key components in the manufacture of electrolytes for lithium-ion batteries
and is now in a position to carry out the development of new generation salts
Dedicated to battery technologies, the Christian Colette Center of Excellence was established and installed within the Centre de Recherche Rhône-Alpes on this platform in 2021
Close to €100 M have been invested for over 10 years in maintenance
as well as in R&D to improve the site’s security and safety
and develop new high added value and resilient activities and product ranges
thus capitalizing on the emergence of new markets in Europe
in particular in Lithium-ion batteries for electric vehicles
To support the growth of materials for the lithium-ion batteries market
Arkema announced in November 2021 a project to invest in a production line for a new Kynar® PVDF biosourced product range on the Pierre-Bénite site
These new grades will be produced from a pine oil derivative
a pilot line dedicated to the pre-industrialization of the next generations of electrolytes for the batteries of the future is already operational
more information
As part of its societal commitment
Arkema operates as a responsible manufacturer driven by an initiative of constant progress in reducing the environmental footprint of its activities
every year the Pierre-Bénite site conducts hundreds of measurements and sampling points in water and air and in the analysis of its wastes in order to monitor and control its emissions and comply with current regulations
the plant complies with the European directive on the control of major-accident hazards
Always aiming to limit the impact of its activities on the environment, the Pierre-Bénite production unit is certified ISO 14001
the site installed a treatment plant to filter out suspended solids
Arkema has deliberately undertaken a process to substitute fluorinated additives used in small amounts in the manufacture of certain products
Thanks to a major multi-million euro R&D program
the Group today is a pioneer in the development of an industrial technique for the manufacture of fluoropolymers without the use of fluorinated additives
and the Pierre-Bénite site no longer resort to fluorinated additives since 2024
the latest industrial investment announced at the end of 2021 includes a new €3 M treatment plant for production process effluents
Update on the PFAS situation at the Arkema site in Pierre-Bénite
As part of Common Ground®, the CETIA and CRRA of Pierre-Bénite organize actions with elected officials
Presence at the Mondial des métiers
Sponsor of the Envol trophée (Pierre-Bénite’s international athletics meet) and of the Les foulées de Beauregard sports festival in Saint-Genis-Laval
Hosting of the cinema workshop at the social center Graine de vie in Pierre-Bénite for a film shooting
Meeting with stakeholders (elected officials
Partnership with NATURAMA to preserve local biodiversity
Interview with an employee with a disability as part of the “La tête de l’emploi” (Right Person for the Job) series
and administrative expertise brought together at the CETIA contributes to the performance of Business Units (BUs) and industrial sites
It is a group of around 500 people in six entities with innovative engineering and focusing on excellence and sustainable development:
which was set up in 2001 to bring together all the group's textile subsidiaries
into three buildings built around patios and linked by an aerial walkway.The extension will see the installation of a new printing line
to be supplemented by a second line by 2024
"in order to continue the industry's innovation drive and contribute to the development of printing expertise in the 'Lyon-style' setting that is emblematic of the House," explains the company in a press release
pointing out that Holding Textile Hermès was awarded the "Living Heritage Company" label in 2022
The Auvergne-Rhône-Alpes French region and the Compagnie Nationale du Rhône (CNR) have announced the construction of a one-kilometer hydrogen pipeline between the Pierre-Bénite dam and the Saint-Fons chemical valley by 2025
The project consists in building a pipeline between the Pierre-Bénite dam and the Chemical Valley in Saint-Fons
The hydrogen would be produced with water from the Rhône River thanks to a 20 MW electrolyser
It will produce 8 tonnes of hydrogen per day
it would be sent to Symbio’s industrial site
The joint venture between Faurecia and Michelin will produce some 200,000 fuel cells per year at its Saint-Fons plant by 2030
with an annual capacity of 50,000 hydrogen fuel cells from the outset
the pipeline will also be used to supply a refuelling station set up by Hympulsion for buses and coaches
A refuelling point should also be added near the port of Lyon for boats
It should be noted that the project will also link up with the actors of the HyPSTER project
the President of the region Laurent Wauquiez said that “80% of the hydrogen players in France are in our region.” He added: “We expect 150,000 jobs to be created in France by 2030 in this sector
The region is thinking bigger as it also intends to connect to a mega pipeline linking Germany to Fos-sur-Mer
Do you want to learn more about hydrogen pipelines? Then our latest articles about the subject should interest you. You can access all our articles written about hydrogen pipelines here
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translated by Marina Leite and reviewed by Logan King
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Associations and residents near the Pierre-Bénite plant in the 'chemical valley' are taking legal action against the company
after an investigation revealed high levels of PFAS in the blood of local inhabitants and employees
By Stéphane Mandard and Stéphane Horel
he had to undergo total removal of a testicle after being diagnosed with a tumor
a small commune in the Rhône department close to the "chemical valley" south of Lyon
the area of France most polluted by PFAS (per-and polyfluoroalkyl substances)
Ever since he learned a few months ago that the water in his community was contaminated with these highly toxic chemical compounds
he has been unable to avoid making the connection with his little boy's illness: "We don't know for sure
but we do know that exposure to PFAS increases the risk of developing testicular cancer tenfold
37 residents of the "chemical valley" (including 16 children) and 10 associations and unions have decided to take legal action to put an end to the pollution
they applied to the Lyon criminal court on May 25 for an environmental penal sanction against the Arkema chemical group
which is responsible for major PFAS discharges into the Rhône
"We have chosen a fast-track application to stop Arkema discharging PFAS into the Rhône as quickly as possible
and to measure the extent of the contamination by taking new samples
at the polluter's expense," explained Camille Panisset
general secretary of the Lyon branch of Notre Affaire à Tous
which filed an initial application a year ago
estimates that "more than 350,000 people are affected by this health and environmental scandal."
when an investigation broadcast on television channel France 2's Envoyé Spécial program detected high levels of forever chemicals in the air
soil (the stadium in the municipality of Pierre-Bénite) and breast milk (young mothers are now among the plaintiffs) around Arkema
which had been discharging large quantities of PFAS into the Rhône for decades
You have 66.26% of this article left to read
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Luxury French company is planning to extend the capacity of its French factory located in Pierre Bénite with the aim of satisfying the demand of Asian market
Luxury French company has explained that is planning to expand its facilities and the number of employees in its factory of Pierre Bénite
The group is planning to extend the production level up to three buildings and hire 120 new employees that will join the 460 workers that are already operating in the factory
The aim of the group’s factory expansion is responding the Asian consumers demand
The company closed the last exercise with a volume of business of 5,966.1 million euros
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Global chemical supplier Nippon Shokubai and materials science specialist Arkema plan to establish a joint venture to build an industrial plant for the production of LiFSI
The project is intended to support the development of the European battery value chain
The partners mean to enable the mass production of LiFSI electrolyte salt at Arkema’s Pierre-Bénite site in France by the end of 2025
The JV will combine Arkema’s fluorochemicals expertise and Nippon Shokubai’s know-how in the industrial-scale production of high-purity LiFSI
The partners built a LiFSI pilot production line based on a new integrated process that they developed
and this line came on stream at the Pierre-Bénite site in 2021
The companies predict that ultrapure and high-performance LiFSI electrolyte salts
will “speed up the development of new electrolyte formulations for the next generations of batteries
including semi-solid and solid-state batteries
while reducing charging time in high or low temperature conditions.”
Source: Nippon Shokubai
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In a context of rapidly accelerating growth in electric mobility around the world
including greater energy density and shorter charging time
greater autonomy and lighter weight of vehicles
today represent key R&D areas to meet the challenge of energy transition
Thanks to its recognized expertise and unique offering of innovative
Arkema is ideally positioned at the heart of the battery ecosystem to support its customers and partners in the clean mobility revolution
Arkema is thus one of the world's leading suppliers of high-value-added solutions: PVDF for binders and separator coatings
and bio-based polyamide 11 to cool battery lines
This Center of Excellence dedicated to batteries for clean mobility is equipped with state-of-the-art design and analysis equipment
including a dry room and an electrode coating line
It draws on the scientific and technical complementarity of the Pierre-Bénite Research Center’s researchers
which will help accelerate the development of advanced materials and processes for future generations of more efficient
has been co-financed by the European Union as part of the European Regional Development Fund (ERDF)
with the support of the Region Auvergne-Rhone-Alpes
named the Christian Collette Center of Excellence for Batteries
in honor of the Group's R&D Vice President who passed away last April
is inaugurated in the presence of numerous customers
The teams will conduct research with the Group's academic partners (CNRS
LEPMI in Grenoble and ENSCM in Montpellier)
as well as with partners in the battery ecosystem
with which strategic agreements have been concluded (start-ups
To support the exponential growth in demand for lithium-ion battery cell materials in Europe
Arkema also announces a 50% expansion of its Kynar® fluoropolymer production capacity at its Pierre-Bénite site
These polymers are used as separators coatings or as cathode binders
New innovations and product ranges will also be offered
the new Kynar® PVDF made from renewable sources
This new extension should come on stream in the first quarter of 2023
This investment benefited from State support as part of the "France Relance" plan
These projects are perfectly aligned with the Group's strategy aimed at accelerating its growth by fully leveraging its unique positioning in high-stakes markets such as batteries
and at offering its customers and partners innovative high-performance and breakthrough materials to help build a sustainable world
I spoke with Fink about what rationing health care during COVID really means
Our conversation has been edited and condensed for clarity
Mary Harris: You’ve said many hospitals are in the first stage of their pandemic handbook
And that means they aren’t officially rationing—yet
Sheri Fink: They’re telling me they’re in this contingency mode where they’re just stretching
where it’s incredibly difficult for the providers
where the patients aren’t able to get the kind of care they would like to provide
is that a lot of regular types of care are being canceled—if you can hold off on a surgery
These have been called “elective procedures.” But if you’re the one waiting to have your tumor out
It seems to be trickling down to people in emergency situations
It hasn’t felt like all these people arrive and you choose between them
It’s this horrific situation where a lot of patients are not getting regular care
You’re being denied the type of care that would be most recommended
That’s what we call a “standard of care,” what would typically be given to you
And there can be more risk with missing out on that care
even survival from COVID has been lower in stressed hospitals
Sometimes it does come down to choosing who gets a dialysis machine or an ECMO machine— when your lungs aren’t working and you need a machine that does the work of the lungs
That is something that’s been rationed for sure
There are not many hospitals that provide the machines
and the number of hospitals that provide it can only give it to a few patients
So there are definitely cases where there have been choices about which patients get a particular resource
dialysis: Sometimes everybody’s gotten a shortened course of dialysis rather than giving a full course to one person and nothing to another person
there are shortages of staff because workers are getting burned out after a long time too
I feel like that’s all affecting just when we lean on these crisis standards of care
The extraordinary sacrifice of providers and the stress and their dedication—there are now
many stories about just how difficult this is
I’m hearing a lot that there’s an active antagonism toward the medical community
I had one doctor say to me that “Our hospital is full of patients dying of COVID who don’t believe that this pandemic exists.” There are many layers to this
I can’t stress enough how much these people care
so hard for them to watch so many people die
There’s one other level that we haven’t talked about
and that is that some of these crisis-standards-of-care plans envision a situation where somebody has a resource like a ventilator or a critical care bed and doctors expect this patient won’t make it—or that the patient has maybe less of a chance to make it than other patients—and the resources are actually reassigned to somebody else
What really adds to the emotional difficulty there is that in a lot of hospitals
during COVID surgeries or while in units that treat patients
the families aren’t being allowed to visit
you can imagine that doctors and nurses barely have time to make phone calls
But they’re trying really hard to stay in touch with family members
and it is harder to wrap your mind around the situation in a hospital with your relative or loved one when you can’t actually be there
“crisis standards of care” have showed up in the form of a high rate of transferring patients
There are rules for how to withdraw care without the consent of patients if they fail to improve after a certain period of time
Some come with elaborate point systems to help assign relative value to different types of people
Some of those systems incorporate patients’ long-term chances of survival
But using a point system like this is also relatively untested
and these plans often don’t go in front of the public for feedback before they’re put into action
So doctors are understandably wary of putting the exact “crisis standards” into practice
I would say that I’ve really been stretching to find a place that is using these plans as written
I will also point out that there’s always been a problem with these plans because there’s not a lot of research that suggests that you will meet your goals by using these scoring systems
The whole purpose of choosing who gets the resource based on a scoring system
the whole goal is to maximize a certain outcome
Do you look at whether that person has underlying conditions
That’s the other question: Who gets to make that choice
a group of people from a particular socioeconomic and educational background
It has been troubling to look at some of these plans and feel that they didn’t have a lot of input
there wasn’t a huge public awareness of them
and there wasn’t even a lot of awareness among providers that states and hospitals were coming up with these plans
now that they’re being noticed and written about
A number of disability rights organizations have filed complaints with the Office of Civil Rights at the Department of Health and Human Services to say that if you implement some of these plans as written
you will discriminate in ways that are unlawful
Some had these aspects that sound very discriminatory
that may have nothing to do with maximizing survival
And there are people who would argue that it should be randomized
because all of this has a danger of reinforcing structural inequities in our health system
The more light that shines on these documents
The other big issue is that these plans are not so easy to implement
a lot of these hospitals wouldn’t even need to consider these standards
but they’re just not distributed correctly
What would that look like if we did do this better
Would it look like physicians relocating from a place like New York and having a more fluid workforce
There is some coordination going on for getting providers from other places
and there are some very wonderful steps that some hospitals are taking to voluntarily care for patients from other places
But there are places in the world where there’s a much more organized approach to this
where they’re one step ahead and they’re keeping track in real time and they’re actually moving patients ahead of getting into crisis mode
But that’s just not being done for various reasons
and often they’re taught to think of themselves as little islands that have their own departments of health and that communicate with their own hospitals
But we do this coordination during events like hurricanes
We do it when large numbers of patients have to be moved
sometimes—is that we’re more than a year into this pandemic
and we’re still in this situation that’s unconscionable
we’re in what is the fourth surge for many places
We’re not going to get into this situation again.” There hasn’t been a lot of “What did we learn from it and what can we implement?” I feel that we haven’t learned enough
though we’ve had a chance to improve within the crisis
InvestigationThe investigation by 'Le Monde' and 17 media partners revealed the presence of dozens of French sites where the pollution levels are considered hazardous to health
The contamination of the European continent by per- and polyfluoroalkylated substances (PFAS)
ultra-toxic compounds that are persistent in the environment
Le Monde and its partners in the Forever Pollution Project investigation have identified several hundred polluted sites in France
as well as five of the 20 European PFAS production plants
This is the first attempt to measure and map the extent of this contamination in Europe
While there are more than 900 contaminated sites in France
this staggering figure greatly underestimates the reality and extent of pollution by these chemicals
Their persistence in the environment has earned them the nickname "forever chemicals." To locate these sites
we collected data from several public databases containing sampling data
are contamination "hotspots" – places where PFAS concentrations are so high (more than 100 nanograms per liter [ng/l]) that they are considered hazardous to health by relevant experts
A number of these hotspots were identified in the 2010s by a team of researchers from the Nancy Laboratory for Hydrology of the French Agency for Food
Environmental and Occupational Health and Safety (ANSES)
After several months of solving scientific riddles and thanks to a freedom of information request
we were able to identify about 30 of these sites
from Pierre-Bénite (south of Lyon) to the Mediterranean Sea
owe their contamination to the discharges of only two factories: Arkema and Daikin
You have 83.37% of this article left to read
Arkema accelerates its development in China in order to meet the strong demand from its partner customers in the lithium-ion battery business and support the significant growth in the water filtration
also recently announced a 50% PVDF capacity increase at its Pierre-Bénite site in France, which is scheduled to come on stream in the first quarter of 2023
We are committed to supporting the growth of our customers
driven by strong end-user demand for sustainable solutions
Industry news and insights from Europe and around the World
Keep up-to-date with the latest new products and technology
FRANCE: Arkema is planning to shut down its R134a refrigerant plant at Pierre-Bénite
Faced with an expected decline in demand for R134a under the European MAC Directive
which bans the use of the refrigerant in all new cars
the French refrigerant manufacturer is proposing to close the plant in the first quarter of 2017
In a statement yesterday the company said: “The R134a market in Europe is set to undergo an inevitable decline from 1st January 2017 following regulatory changes affecting fluorinated gases for automotive air conditioning taking effect on that date
Arkema has decided to put forward to the central works council today a project for the closure of the R134a fluorogas plant at its Pierre-Bénite site (France)
This proposed closure would not result in any redundancies.”
The automotive air conditioning market is said to be the main outlet for Arkema’s R134a business in Europe
Arkema says it will focus its refrigerant activities at the Pierre-Bénite site on the production of other fluorinated refrigerants and blends for the stationary air conditioning and refrigeration markets
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where creativity and craft unite to make the iconic Hermès ‘carré’ – a square-shaped silk scarf adorned with prints by renowned artists and illustrators
across two sites where each scarf is printed and finished by hand
‘When you see all of the steps,’ says Cécile Pesce
the current creative director of Hermès women’s silk
across the two sites on the outskirts of the city – the Bourgoin-Jallieu site to the south-east and the recently extended Pierre-Bénite closer to the centre – the process of creating a carré harks back to the accessory’s invention by Hermès family member Robert Dumas in 1937 and remains led by the artisan’s hand in the face of modernisation
the hand-inscription of the original design – patterns are commissioned from a series of notable artists and illustrators – into an image editing programme
the team nonetheless painstakingly traces each brush or penstroke by hand using a drawing tablet and stylus in a process which takes on over 600 hours for each scarf’s design (several have taken far longer)
Hermès inaugurated the newly expanded Pierre-Bénite site
which now includes a sleek three-building extension surrounded by verdant gardens created by Lyon-based architecture studio Unanime (it even includes its own vegetable patch
state-of-the-art screenprinting machines have replaced the labour-intensive process of hand-dragging the ink over the screens; another production line is set to be added in the coming months
The site is also where the Willy Wonka-esque process of creating the now over 75,000 shades in the Hermès colour catalogue are mixed and perfected into their (secret) formulas.
colour is perhaps the central facet of Pesce’s role as creative director
which she began in 2020 having worked in the silk department since 2005 (she has also designed collections for Hermès’ ‘beach universe’ since 2014
Pesce is responsible for choosing the colours that best fit the designs that the artists have submitted
as well as updating archival prints with new hues
she demonstrates how different a singular design can appear with the colours shifted and changed
choices are intuitive: ‘[The colours] are mixed from memories
The idea is to reorganise everything; colours are like words to make a sentence,’ she says
‘Or how it is to make music: it is natural for me.’
Pesce notes that it is often easier when the carré utilises numerous shades rather than just a handful
it’s easier because they feel equal to one another,’ she explains
‘But when you just have five colours
You have to respect the different shades – from dark to middle to very bright and the lightest lights.’
whereby Hermès united with a producer in Kyoto
undertaking historic marbled silk printing
captured in a short film by Frédéric Laffont.
escapism and design stories from around the world direct to your inbox
She notes that craft – and the artisans who work on the various silk pieces – remain the bedrock of her métier at Hermès
‘I really like to spend time in the workshop – I have a lot of respect for the artisans
noting that she travels down to Lyon when she can
and around people who are passionate about their work.’ Of the house’s signature silk product
around 1,000 artisans and craftspeople will gather at the new factory site in Pierre-Bénite for its official opening in a celebration that includes musical performances
Bunting made from cut-up triangles of printed Hermès silk flutters overhead
and there is excitement in the air; the festivities will mark a rare halt in production
as everybody will take the day off to toast the occasion
but something much more – a network of artisans across France and beyond
dedicated to working together to unite on the dizzying expressions of craft and creativity which are now synonymous with the bastion of French style
‘It really is a family affair,’ she smiles
hermes.com
Fashion Features EditorJack Moss is the Fashion Features Editor at Wallpaper*
Having previously been the digital features editor at AnOther and digital editor at 10 and 10 Men magazines
he has also contributed to titles including i-D
while also featuring in Dazed: 32 Years Confused: The Covers
He is particularly interested in the moments when fashion intersects with other creative disciplines – notably art and design – as well as championing a new generation of international talent and reporting from international fashion weeks
he has interviewed the fashion industry’s leading figures
France's industry minister Roland Lescure denounced the protest on Friday
declaring on social media platform X "Disagreeing and debating
This image grab taken from AFPTV footage shows Extinction Rebellion and Youth for Climate activists deploying a giant banner depicting a skull and bones
atop a structure inside the Arkema chemical plant after they entered the site to protest against pollution caused by polyfluoroalkyl substances (PFAS)
SYLVAIN THIZY / AFP Environmental activists broke into a French chemicals site Saturday
March 2 to denounce the production of so-called "forever chemicals" – PFAS compounds – leading to eight arrests
Around 300 people from the Extinction Rebellion and Youth for Climate groups cut through fences to reach the Arkema site at the Pierre-Bénite factory near Lyon in southeast France
Once inside they deployed banners and spray-painted graffiti including "PFAS tell the truth" and "Arkema is poisoning us"
"We want to close to door for the 'forever chemicals' that Arkema is dumping into the Rhone river," Julien
we want to open the door because everything that's happening here is being done in secret," he said
are a family of around 4,000 chemical compounds often referred to as "forever chemicals" because of their long lifespans in bodies and the environment
Experts say that exposure to some types of PFAS has been linked to serious health effects
American regulators said this week that materials with PFAS would no longer be sold to package microwave popcorn or other greasy foods in the United States
Arkema said in a statement that the Pierre-Benite site would stop using PFAS compounds to manufacture its products by the end of this year
The protest came as another chemicals group
is seeking to build a new production site nearby
Regional authorities said: "The new site from Daikin will not lead to PFAS runoffs in the water
unlike the Arkema site which has been subject to a September 2022 decree that calls for halting the use of PFAS surfactants by the end of 2024."
Metrics details
Surgical site infections (SSI) occur in 1.4% to 33.4% of cases after orthognathic surgery
This type of complication is a major concern to surgical teams
but there is no consensus for the prevention and treatment of SSI in orthognathic surgery
The purpose of this descriptive study was to evaluate the severity and the consequences of postoperative infections
The charts of all the patients operated on by the orthognathic surgery team between January 2015 and July 2017 were collected
All types of orthognathic procedures (Le Fort I maxillary osteotomy
bilateral sagittal split mandibular osteotomy
and patients diagnosed with SSI were included
as well as long-term complications were recorded
Five hundred and twelve patients were screened
Forty-one patients (8%) presenting with SSI were included
The site of the infection was mandibular for 38 patients (92.7%) and maxillary for 3 patients (7.3%)
The average time between surgery and infection was 31.5 days
Twenty-four patients received isolated oral antibiotics for inflammatory cellulitic reaction (58.8%)
15 patients had a localized collection treated by incision and drainage under local anesthesia (36.6%)
and 2 patients had an extensive collection requiring surgical drainage under general anesthesia (4.9%)
Five patients (12.2%) needed hardware removal for plate loosening
and 2 patients (4.9%) developed chronic osteomyelitis
Infection following orthognathic surgery is easily treated most of the time with no long-term complications
In cases of patients with potential risk factors for severe infection
antibiotics may be given with curative intents
All patients were followed up for at least 6 months
Informed consent was obtained from all participants
This research was approved by the local ethics committee (Collège régional de Chirurgie Maxillo-Faciale) on May 2
and was performed in accordance with the guidelines reported in the ethical principles for medical research involving human subjects (World Medical Association Declaration of Helsinki)
Le Fort osteotomy was performed using a reciprocating saw or Piezotome
Fixation of the maxilla and BSSO was obtained using titanium mini plates
Third molars were removed at the time of surgery if necessary
Surgical wounds were sutured with Ethicon coated VICRYL 3.0 sutures (Johnson and Johnson International)
Standard post-operative care and oral hygiene instructions were given to each patients
antibiotics were prescribed for 10 to 15 days and oral hygiene was re-emphasized
The first line antibiotic was AMOXICILLIN CLAVULANIC ACID 1 g every 8 h
CLINDAMYCIN 600 mg every 8 h was the second line treatment in case of penicllin allergy
When the clinical and radiological evaluation demonstrated a collection
a surgical drainage was performed: local collection were drained under local anesthesia and irrigated with a normal saline solution
Extensive collections were drained under general anesthesia
In case of osteomyelitis (Fig. 1), the patient was managed in collaboration with the infectious diseases department. Following surgical cleansing and bacteriological sampling, culture directed antibiotics were selected and administered for a period of 6 weeks to 3 months.
Axial view of Cone Beam CT: right mandibular osteomyelitis
The following variables were collected: medical history (including tobacco use
immunosuppressive treatment or pathology) age
Every complication occuring in the 6 months following surgery was documented
surgical drainage and patient’s evolution were recorded
The initial SSI severity was defined by the following presentations: cellulitic reaction treated with oral antibiotics
local collection requiring surgical drainage under local anaesthesia
and extensive cellulitis needing surgical drainage under general anesthesia
Local evolution according to initial presentation.
Extensive cellulitis with purulent collection after bilateral sagittal split osteotomy (CT scan
One of the two patients presenting with osteomyelitis was treated for rheumatoid arthritis with METHOTREXATE and ADALILUMAB. These treatments were discontinued 2 months before surgery (Fig. 1)
The 2 cases of osteomyelitis resolved under medical treatment without requiring interruptive mandibulectomy
Short-term prophylaxis reduces adverse effects
decreases selection of resistant bacterial strains
systematic antibiotic treatment cannot be recommended given the available evidence
the low rate of local complications as well as the plethora of possible adverse effects from extended antibiotic therapy support the indication for single dose preoperative antibioprophylaxis
The delay found in the current study might be overestimated
the date of infection was noted as the date at which the patient presented out medical attention on our service
the patients treated for long-term complications in our series were older with an average age of 37.5 years as opposed to 19.6 years for patients needing only hardware removal and 23.4 years for those recovering promptly following oral antibiotics only in the rest of the series
Radiographic evolution of osteomyelitis: diagnosis (A)
1 day after hardware removal and surgical curettage (B)
and 1 year after the antibiotic treatment (C)
The dataset analyzed for this study is available upon request to the corresponding author
Maxillary osteotomy complications in piezoelectric surgery compared to conventional surgical techniques: a systematic review
Unusual and rare complications of orthognathic surgery: a literature review
Les infections du site opératoire en chirugie orthognathique et leurs facteurs de risque
Prevalence of surgical site infections following orthognathic surgery: a double-blind
randomized controlled trial on a 3-day versus 1-day postoperative antibiotic regimen
Method of osteotomy fixation and need for removal following bimaxillary orthognathic
and intranasal surgery: a retrospective cohort study
Prescribing antibiotic prophylaxis in orthognathic surgery: a systematic review
Antibiotic prophylaxis in orthognathic surgery: a complex systematic review
Plate removal following orthognathic surgery
Risk factors contributing to symptomatic miniplate removal: a retrospective study of 153 bilateral sagittal split osteotomy
Is the removal of osteosynthesis plates after orthognathic surgery necessary
Antibioprophylaxie en chirurgie et médecine interventionnelle (patients adultes) 2018
Preoperative antiseptics in clean / contaminated maxillofacial and oral surgery : prospective randomized study
Comparison of the histopathological characteristics of osteomyelitis
medication- related osteonecrosis of the jaw
A language and environment for statistical computing
The efficacy of postoperative prophylactic antibiotics in orthognathic surgery: a prospective study in Le Fort I osteotomy and bilateral intraoral vertical ramus osteotomy
Extended antibiotic therapy may reduce risk of infection following orthognathic surgery
Prevalence of postoperative complications after orthognathic surgery: a 15-year review
Stability and surgical complications in segmental Le Fort I osteotomy: a systematic review
Osseous genioplasty in conjunction with bimaxillary orthognathic surgery: a review of 262 consecutive cases
Preoperative antibiotic prophylaxis in orthognathic surgery: and clinical study
A prospective study on infectious complications in orthognathic surgery
Effectiveness of postoperative antibiotics in orthognathic surgery: a meta-analysis
Perioperative antibiotic prophylaxis in orthognathic surgery: a systematic review and meta-analysis of clinical trials
A systematic review of latest evidence for antibiotic prophylaxis and therapy in oral and maxillofacial surgery
Antibiotic prophylaxis for bilateral sagittal split osteotomies: a randomized
Antibiotic prophylaxis for major maxillocraniofacial surgery
Prevalence of surgical site infections following orthognathic surgery: a retrospective cohort analysis
The ef fi ciency of extended postoperative antibiotic prophylaxis in orthognathic surgery: a prospective
Prophylactic single-dose administration of 600 mg clindamycin versus 4-time administration of 600 mg clindamycin in orthognathic surgery: a prospective randomized study in bilateral mandibular sagittal ramus osteotomies
Are postoperative intravenous antibiotics necessary after bimaxillary orthognathic surgery
Fulminant clostridium difficile colitis: a complication of perioperative antibiotic prophylaxis
Smoking is a risk factor of organ/space surgical site infection in orthopaedic surgery with implant materials
Antibiotic prophylaxis in intraoral orthognathic surgery
Antibiotic prophylaxis for orthognathic surgery: a prospective
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Department of Maxillofacial Surgery and Facial Plastic Surgery
Department of Maxillofacial Surgery and Stomatology
Centre Hospitalier Régional Universitaire Jean-Minjoz
translated the manuscript and reviewed the design and analyses
All authors reviewed the manuscript and approved its final version
The authors declare no competing interests
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Arkema plans a 50% expansion of capacity for polyvinylidene fluoride manufacturing in Pierre-Bénite
to meet demand for the polymer as a binder and separator material in lithium-ion batteries
Arkema also just opened a battery research center at the site
The company says the moves support its goal of having sales to the battery market of at least 1 billion euros (about $1.1 billion) per year by 2030
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InvestigationAccording to the estimate calculated by Le Monde and its partners
France would have to spend €12 billion a year on cleaning up PFAS if the smallest of them
which is widely present in water and not yet regulated
Anne Grosperrin is "very concerned by this discovery." Since the end of 2024
Greater Lyon's vice president in charge of the water cycle has known that "the water catchment area that supplies 98% of the population with drinking water is contaminated with TFA."
In the PFAS (per- and polyfluoroalkylated substances) family
The most microscopic of the "forever chemicals," the darling of agricultural and medical chemistry is making its way at breakneck speed through water
A breakdown product of pesticides and other PFAS
You have 92.12% of this article left to read
Part of the A7 motorway near Lyon will be closed for several weekends over the coming months so urgent repairs to a major bridge along the route can be carried out
Works on the Pierre-Bénite viaduct – a bridge that crosses the Rhône a few kilometres south of Lyon – will take place throughout May and the beginning of June.
The bridge sees around 150,000 cars cross it every day
and has been a key part of the motorway since it opened in 1966
the bridge will only be closed in one direction
with traffic heading northbound (towards Lyon) impacted.
Repairs to the opposite side of the bridge will lead to closures in 2026
affecting drivers hearing south towards Marseille.
The bridge will be closed northbound on the following dates:
Tuesday 29 April 29 at 21:00 to Sunday May 4 at 12:00
Wednesday May 7 at 21:00 to Sunday May 11 at 12:00
Wednesday May 21 at 21:00 to Sunday June 1 at 12:00
Friday June 6 at 21:00 to Monday June 9 at 12:00
work may also be scheduled between June 13 - 16 and June 20 - June 23 if the bridge is not repaired by this time
drivers heading into Lyon will need to take an alternative route
using the A46 motorway and the eastern portion of the city’s ring road.
Read more: Map: where are there free motorways in France?
The prefectural ban is set to remain in place until at least December 31
There are new boxes in the address and personal details page of the 2025 online declaration (for 2024 income)
The geographical spread of Canadian nationals follows a similar pattern to Americans
Jérôme Moroge (LR) a été réélu maire de Pierre-Bénite avec 63.48% des suffrages
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