You don't have permission to access the page you requested What is this page?The website you are visiting is protected.For security reasons this page cannot be displayed OGC Nice claimed a narrow but crucial 1-0 victory over Stade de Reims on Friday night to move provisionally into third place in Ligue 1 A first-half goal from Morgan Sanson was enough to separate the sides but Francesco Farioli’s men were made to suffer during a tense and disjointed second half The only goal of the game came in the 15th minute A long ball from Melvin Bard into the Reims box caused confusion between defender Okumu and goalkeeper Diouf Their miscommunication allowed Morgan Sanson to pounce and slot into an empty net – his third goal in as many games and a rare highlight in an otherwise lacklustre attacking display from the hosts with Reims struggling to make inroads and recording just one touch inside the opposition box by the 32nd minute The Gym were composed without being threatening and a quiet Allianz Riviera saw out a rather uneventful first 45 minutes Will Still’s Reims came out with more intent in the second half and began to stretch a Nice side that clearly dropped off physically and tactically The visitors created multiple clear-cut chances: Junya Ito forced a good stop from Marcin Bulka while Oumar Diakhon and Mohamed Daramy – both second-half substitutes – added much-needed dynamism The best opportunity fell to Ibrahim Diakité in the dying seconds of added time but his close-range effort was blocked by a teammate after Diakhon’s initial strike was deflected were relieved to hear the final whistle after eight minutes of stoppage time While Nice climb into third place – at least temporarily – and take a significant step toward European qualification Reims missed a golden opportunity to mathematically secure their Ligue 1 survival Still in 13th place with three matches remaining they remain five points clear of the relegation play-off spot The evening marked a first Ligue 1 start for 18-year-old midfielder Ange Tia, who impressed in flashes before being forced off early in the second half with what appeared to be cramp. It was an encouraging outing for the Malian youngster despite the result.READ MORE: >>Paris FC clinch historic promotion to Ligue 1 McDonald's This website is using a security service to protect itself from online attacks The action you just performed triggered the security solution There are several actions that could trigger this block including submitting a certain word or phrase You can email the site owner to let them know you were blocked Please include what you were doing when this page came up and the Cloudflare Ray ID found at the bottom of this page Samba Diawara provided a positive update on Junya Ito’s ankle injury earlier this week the Japanese international is not expected to be fit to face OGC Nice Stade de Reims head to the Côte d’Azur with the hope of getting a win that would potentially confirm their safety in Ligue 1 they will have to do so without their key player The Japan international came off injured during the 0-0 draw against Montpellier HSC last weekend There was a fear that Ito had suffered a serious injury stating that the forward had not suffered a sprain Diawara confirmed he would need a few days’ rest and so he misses Reims’ match against Nice on Friday night GFFN | Luke Entwistle OGC Nice tightened their grip on a potential Champions League spot with a narrow 1-0 victory over Stade de Reims in Matchweek 32 of Ligue 1 thanks to an early strike from Morgan Sanson The decisive moment came in the 15th minute when Sanson slotted home what proved to be the match-winner as Nice held firm for the remainder of the contest While Paris Saint-Germain have already secured the Ligue 1 title the race for European qualification is still wide open — and this result could prove crucial who are yet to play their fixture this round comfortably mid-table but with little left to fight for as the season winds down 15 (1:0)Nice: Bulka; Abdi Ali; Bard M.; Mendy An 69); Bombito; Clauss J.; Boudaoui (Santamaria 89)Bench: Dupé; Boga; Louchet; GuessandYellow Cards: Rosario 6; Mendy An 65); NakamuraBench: Olliero; Jeng M.; Sangui; MoscardoYellow Cards: Gbane 62; Nakamura 72 [email protected] Allianz Riviera Stadium is set to host the exciting matchup between home side OGC Nice and visiting club Stade de Reims on Friday in Ligue 1 action The hosts are unbeaten in their last 12 matches against the club from Reims in the French top flight with four wins and eight draws in that span The only other time the club from Nice was able to remain unbeaten for 13 consecutive outings against a single opponent in Ligue 1 was when it did so against Lille between August of 2012 and November of 2018 OGC Nice has conceded just two goals in 10 matches at home against Stade de Reims in the French top flight this century was in its most recent meeting at Allianz Riviera a 2-1 victory for Nice in December of 2023 Live stream OGC Nice vs. Stade de Reims on Fubo: Start your free trial today! The hosts head into the meeting on Friday as the sixth-placed club in the Ligue 1 standings with 54 points in 31 matches so far this season to go along with an overall record of 15 wins The club from Nice is coming off of consecutive wins in league play against the likes of Angers SCO and Paris Saint-Germain Pablo Rosario and Ali Al-Abdi found the back of the net in the narrow 2-1 finish over Angers while Morgan Sanson (twice) and Youssouf Ndayishimiye did the same against the club from Paris Don’t miss the thrilling matchup between OGC Nice and Stade de Reims on Friday in Ligue 1 action where we cover everything we air on fuboTV Contact us: support@fubo.tv Morgan Sanson celebrates his goalPSNEWZ / Sipa Press / ProfimediaNice extended their unbeaten H2H record against Stade de Reims to 13 matches with a nervy 1-0 victory at Allianz Riviera, with the win keeping Les Aiglons in the hunt for an automatic place in next season’s UEFA Champions League.Nice came into the game in a buoyant mood having become the first French team to defeat Paris Saint-Germain in the league this season running out 3-1 winners at Parc des Princes last Friday The Aiglons knew they could take advantage of playing before all of their rivals this weekend and put the pressure onto their shoulders Before the game, Manager Franck Haise said his team are “capable of great things”, and whilst they weren’t at their free-flowing best in the first half, they were able to hit the front with 15 minutes on the clock when a chipped ball into the area wasn’t dealt with by the Reims defence and it fell kindly to Morgan Sanson who swept it into an empty net for his third goal in just his second start of the season there wasn’t much to write home about in a first half that saw both teams only muster a single shot on target apiece with Reims’ poor record in this fixture undoubtedly on their minds as they struggled to make an impression The key statsOpta by StatsPerformHaving done enough to take a one-goal lead into half-time the hosts were keen to press on after the restart Haise’s men have only lost twice at home in Ligue 1 this season but those two reversals did come in their last four matches and they weren’t looking particularly convincing against their lowly opposition The home fans would have been concerned by the fact their team’s last six matches had seen both sides score with Les Aiglons doing little to threaten a second goal and they were almost punished with just over 20 minutes remaining when a ball across the area found Valentin Atangana unmarked but the midfielder lost his footing slightly and saw his close-range effort fly over the crossbar The Red and Whites looked the likelier team to find a goal late on but Nice did just about enough to keep them at bay and hold on for a victory that lifts them into third for the time being while Reims will have to wait until next week to mathematically secure their Ligue 1 safety as they sit 13th five points clear of the drop zone with two games remaining Flashscore Man of the Match: Morgan Sanson (Nice) You can find more about the match here. Japan attacker Keito Nakamura took his season's tally to 11 goals in the French Ligue 1 with a brace on Friday as Reims claimed a 2-0 win away to Lens The 24-year-old steered high into the net for the 33rd-minute opener at Stade Bollaert-Delelis off a low left-wing cross from Sergio Akieme reaching double figures for goals in one of Europe's five major leagues Reims keeper Yehvann Diouf stood firm as the visitors held on to the lead before Nakamura's second in the 88th minute after substitute Nhoa Sangui launched a counter from inside his own half and set up the Japanese to side-foot into the far bottom corner The win moved Reims up to 14th on 29 points and out of the relegation zone attacker Kodai Sano drilled in a left-footed opener 15 seconds into the second half for his second goal this term in the Eredivisie helping NEC Nijmegen secure a late 2-1 over RKC Waalwijk Football: Celtic's Maeda nets 30th goal, Nakamura stars in Reims win Football: Ayase Ueda back scoring as Japan near fastest 2026 World Cup spot Football: Daizen Maeda hits brace as Celtic smash Aberdeen To have the latest news and stories delivered to your inbox Simply enter your email address below and an email will be sent through which to complete your subscription Please check your inbox for a confirmation email Thank you for reaching out to us.We will get back to you as soon as possible OneFootball's home page Search Settings Sign In Sign InJoinPREVIEW | Nice vs Stade de Reims - team news Nice host Stade de Reims this Friday at the Allianz Riviera on Match Day 32 of the Ligue 1 Nice have won 54 points to date and are placed in 6th position. Last time out, Franck Haise's team triumphed 1-3 against PSG (Ligue 1 2024/25) Stade de Reims have 33 points to their name this season and occupy 13th position in the table. In their last outing, Stade de Reims drew 0-0 against Montpellier (Ligue 1 2024/25) The last meeting between the two teams ended with Nice winning 4-2 Related NewsPLAYER RATINGS | OGC Nice 1-0 Reims: Morgan Sanson takes <i>Le Gym </i>onto the podium Reims predicted XI v OGC Nice: Junya Ito out OGC Nice predicted XI v Reims: Franck Haise’s defensive options limited Nico Schlotterbeck reinforces his commitment to BVB Nico Williams and Oihan Sancet miss training for Athletic Club Crystal Palace 1-1 Nottingham Forest: Eberechi Eze scores as Eagles get ready to peak in FA Cup final Glasner will be content with his side’s performance against a team chasing Champions League qualificationCrystal Palace had their chances and could have nicked it late on, but a 1-1 draw... 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Flying high after their famous win at the Parc des Princes last weekend OGC Nice kick-off what will be another tense weekend of action as the battle to the UEFA Champions League and European spots heats up with just three Match days left of the season They face a Reims outfit at the Allianz Riviera that are hoping to seal mathematical safety as they travel to the Côte d'Azur during Friday night's action Les Aiglons are full of confidence following their big win over PSG thanks to a brace from former Marseille man Morgan Sanson and a stunning third from Youssouf Ndayishimiye to seal the end of Les Parisiens' invincible streak in Ligue 1 McDonald's this season Le Gym are now just three points behind Riviera rivals Monaco - with only four points separating Marseille in second all the way down to Strasbourg in seventh place it's a huge achievement," said Nice boss Franck Haise following his 3-1 win over the Champions last Friday evening "The hardest part is reproducing a performance like that." Reims drew against bottom side Montpellier at Stade de la Mosson Samba Diawara's men have a cushion of five points to 16th-placed Le Havre and  six point lead over Saint-Étienne meaning they could mathematically tie up safety with just a draw against Nice on Friday evening Les Rémois will have to travel to the South with a doubt for Junya Ito who had to come off against Montpelier with an ankle injury the Reims coach said in his press conference that the player had "a large bruise "It's a bruise that will still require a few days' rest he can walk normally and has been out on the pitch for a bit even though there could be a dramatic improvement between now and Friday >>One to Watch: OGC Nice's Polish wall Marcin Bułka could be key to European aspirations OGC Nice’s defensive options are limited as they prepare to host Stade de Reims at the Allianz Riviera The club are reeling after two major injuries in the space of the last week Mohamed Abdelmonem was the first to suffer an injury He ruptured his ACL in an innocuous duel against Paris Saint-Germain on Friday and will be out for several months The same fate then befell Youssouf Ndayishimiye He suffered the injury during a duel in training on Wednesday and like his Egyptian teammate will now face a considerable spell on the sidelines Dante returns having missed the win against PSG last weekend with a minor knee injury Franck Haise’s options at the back are therefore limited OGC Nice edged out a spirited Stade de Reims side (1-0) thanks to a first-half goal from Morgan Sanson It sees Franck Haise’s side move provisionally into third place in what is an important win in their attempts to secure UEFA Champions League football Reims have been labelled as a team that can’t or won’t play an attractive form of football but at times who created few chances but gave up plenty to what is considered an inferior opposition Chances were at a premium but Le Gym were provided a glorious one on the 15-minute mark when a dangerous ball into the box landed simultaneously in Yehvann Diouf’s and Joseph Okumu’s goal The goalkeeper was obliged to come but didn’t take the ball who put it on a plate for Sanson to turn it into the empty net Les Aiglons had more possession but it was Les Stadistes who had the better chances in the second half Amadou Koné found himself in a glorious position after a high turnover but with a clear sight at Marcin Bulka’s goal he could only shoot straight at the Poland international Moïse Bombito’s poor positioning saw Keito Nakamura played in on goal but his curled effort was tepid It felt premature and Reims did keep pushing but they could not find the equaliser with Nice holding on for an unconvincing but important victory He looked nervous in the first half and had a couple of ‘moments’ including a slip that almost provided Reims with a glorious chance There is a feeling of what if about Sanson He could have made a huge difference to this Nice side over the course of the campaign had he not been injured for the vast majority of it He popped up in the right position to score his third goal in just two games and was efficient and purposeful in his distribution He has been absent for so long but is now making a big difference in the final sprint His performances against Paris Saint-Germain and Reims are worth six crucial points there was lots of intent and lots of technical quality in his play which hasn’t always been said for Bouanani GFFN | Luke Entwistle – reporting from Nice @2025 - All Rights Reserved. Get Football Group 14. Apr. 2025 / On Monday 14th April 2025 the International Judo Federation ... 12. Apr. 2025 / Koshiki-no-kata (古式の形) corresponds to the form ... 12. Apr. 2025 / Daniel De Angelis is the Director of the IJF Kata Commission. ... 12. Apr. 2025 / Since 13th November 2024, when he took over as head ... 18. Mar. 2025 / The Tbilisi Grand Slam is a firm favourite on the IJF ... 09. Mar. 2025 / On Saturday 8th March, the first Kata World Series ... 04. Mar. 2025 / This is a big premiere, since the first Kata World ... 02. Mar. 2025 / Catherine 'Cathy' Arnaud is a legend of French and ... Seven categories were contested: nage-no-kata, nage-no-kata U21, kagame-no-kata, juno-kata, juno-kata U21, kime-no-kata, and goshin-jutsu. At the end of the day, Italy topped the podium with three gold medals and one bronze medal, closely followed by France with two gold medals, one silver and three bronze medals. In third place was Belgium with one gold, two silvers and two bronze medals. Throughout the day, the participants displayed total commitment, precision pushed to its peak, total concentration and absolute respect. In a few months, most of the judoka present in Reims, and others, will meet again to win the coveted world title. Between now and then, they will all have the opportunity to refine their kata in order to deliver top-level performances. 05. May. 2025 / With Dushanbe already packed away in our recent memory, ... 04. May. 2025 / What can we learn from the 2024 edition of the Dushanbe ... 04. May. 2025 / This is a final category that everyone always looks ... 04. May. 2025 / We've been saying it since the beginning of the tournament: ... 04. May. 2025 / When you've already won the Paris Grand Slam in February ... 04. May. 2025 / The competition was a bit strange for the tournament's ... 04. May. 2025 / European champion in 2024 and a third-place finisher ... 03. May. 2025 / For three days, the world judo capital is in Tajikistan ... 03. 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All rights reserved Reims has all the Gallic glamour of the French capital plus the world’s most famous fizz as its trump card walkable city is the capital of France’s Champagne region and home to all the major champagne houses with their swish tasting rooms and Unesco-listed chalk cellars striking art deco architecture and one of the most impressive gothic cathedrals in France The city’s wartime past is more sobering: it was all-but-destroyed during the First World War while Germany officially surrendered here at the end of the Second World War "},"children":[]}]},{"name":"image","attributes":{"id":"053f37f8-7ef5-4a18-bc88-6118a54b4c78","display":"fullwidth","caption":"St Remi Basilica in Notre Dame Cathedral","title":"Interior of Saint-Remi Basilica in Reims All the big-name champagne houses offer tours but Pommery is the most dramatic place to start with its turreted château and 11 miles of tunnels used for ageing the wine buried 100ft under the city The owner Louise Pommery was the first to make brut champagne in the 19th century and the estate’s warren of dimly lit cellars now double as a modern art gallery with installations alongside bottles of bubbly dating back to 1874 (tours from £23 includes tasting; champagnepommery.com)."}},{"name":"break","children":[]},{"name":"break","children":[]},{"name":"text","children":[],"attributes":{"value":"• Taittinger is the region’s largest family-owned champagne house and one of the most laid-back with a newly opened visitor centre and trendy tasting room where visitors are encouraged to linger for an extra glass or three Its soaring cellars are some of the most spectacular in town originally mined by the Romans then used by 13th-century monks to make wine before becoming an underground hospital during the First World War — it’s still possible to spot graffiti carved into the walls by soldiers (from £33 includes tasting; taittinger.com)."}},{"name":"break","children":[]},{"name":"break","children":[]},{"name":"text","children":[],"attributes":{"value":"• Reims’ Unesco-listed Notre Dame Cathedral is a real gothic showstopper where 25 kings of France were crowned including Charles VII in the presence of Joan of Arc Take a stroll round it at sunset to see its dazzling stained glass windows at their best and spy more than 2,300 statues including one of a smiling angel,"}},{"name":"italic","children":[{"name":"text","children":[],"attributes":{"value":" L’Ange au Sourire"}}]},{"name":"text","children":[],"attributes":{"value":" said to keep watch over the city (free; cathedrale-reims.com)."}},{"name":"break","children":[]},{"name":"break","children":[]},{"name":"text","children":[],"attributes":{"value":"• Stock up on sweet souvenirs at Maison Fossier Its famous crunchy pink biscuits were created to dip into champagne and it’s now possible to watch them being produced largely by hand in the small factory on the outskirts of town End your visit in a gift shop so pink it would make Barbie blush drop by Fossier’s other shop on Jean-Baptiste Langlet (£4.50 for tour and tasting; fossier.fr)."}},{"name":"break","children":[]},{"name":"break","children":[]},{"name":"text","children":[],"attributes":{"value":"• Reims’ significant role in the end of the Second World War is commemorated in the Musée de la Reddition a museum in the same building where the Germans officially conceded defeat on May 7 You can even visit the Map Room where the historic document was signed surrounded by details of casualty numbers and POW statistics exactly as it was on that fateful day (£4.50; musees-reims.fr)."}},{"name":"break","children":[]},{"name":"break","children":[]},{"name":"text","children":[],"attributes":{"value":"• Head to Hautes Promenades park to snap a pic in front of the Reims city sign you can hop on the traditional carousel or even cool off in the splash fountains with an ice cream before strolling back to town to people-watch from one of the many bustling bars in the Place du Forum "}}]},{"name":"image","attributes":{"id":"05b933b7-eb30-410e-bdda-080f44ec83ad","display":"fullwidth","caption":"Maison Fossier is the oldest biscuit producer in France","title":"Biscuits Fossier raspberry biscuits in Reims with its vivid blue wall decor by the comic artist and painter Fabrizio Borrini There’s also a bright terrace for dining alfresco Dishes including snails and beef tartare can all be paired with suggested champagnes You’ll learn to master this ultimate party trick of brandishing a sword to slash the top off a bottle hopefully without taking your hand off you can drink your spoils afterwards (£43; champagne-polcouronne.com)."}}]},{"name":"image","attributes":{"id":"69bc9dce-739f-4211-9b12-81114c87978e","display":"fullwidth","caption":"Café du Palais first opened in 1930","title":"Interior of Cafe du Palais in Reims It’s busy in every sense of the word — decor style and popularity — and is peppered with antiques and artworks under a glass roof created by the celebrated glassworker Jacques Simon lardons and pommes grenailles is a hearty treat (mains from £14; cafedupalais.fr)."}}]},{"name":"heading3","children":[{"name":"text","children":[],"attributes":{"value":"Case à Pain"}}]},{"name":"paragraph","children":[{"name":"text","children":[],"attributes":{"value":"Feast on indulgent French pastries freshly baked bread and rainbow-coloured macarons at wonderfully affordable prices at this informal boulangerie and pâtisserie There’s limited outdoor seating or grab a bag to go for an impromptu picnic in leafy Parc de Champagne The tarte au sucre (£2) is a must-buy (case-a-pain.fr)."}}]},{"name":"heading3","children":[{"name":"text","children":[],"attributes":{"value":"Cuivré"}}]},{"name":"paragraph","children":[{"name":"text","children":[],"attributes":{"value":"If you’ve had your fill of fizz opt for a pint at this hip but relaxed craft beer bar popular with the city’s student population Grab a table with a view of Reims City Hall and order one of 18 beers straight from the copper taps such as rich dark La Lorette Oatmeal stout (from £4; cuivrereims.fr) is near another of Reims’ art deco hotspots the produce-packed Halles Boulingrin food market Brasserie du Boulingrin serves the best market fare in chic bistro surroundings with standout dishes including homemade terrines Breakfast is served on the tucked-away patio while there’s a small drinks menu available at night with two-bed suites to give kids extra space Families are drawn to the swimming pool while the solarium and sauna offer grown-up relaxation with its rich jewel-toned velvet seating and outdoor terrace this hotel is in 17 acres of parklands with 20 rooms and suites sumptuously decorated in classic French style Les Crayères is also renowned for its wine cellars and Le Parc Eurostar travellers can book the high-speed train from Paris Gare de l’Est (a five-minute walk from Gare du Nord) to Reims avoid the harvest in late summer when owners are busiest and may struggle to host guests Note that part of Reims city is a Low Emission Zone To drive here vehicles must display a green Crit Air sticker or an emission sticker rated from 1 to 3 on the windscreen "}},{"name":"break","children":[]},{"name":"bold","children":[{"name":"text","children":[],"attributes":{"value":"Janice Hopper was a guest of Best Western along with unlimited digital access to The Times and The Sunday Times you can enjoy a collection of travel offers and competitions curated by our trusted travel partners complete with compelling history and showstopper cathedrals","slug":"what-to-see-and-do-in-reims-champagne","categoryPath":"/travel/inspiration/city-breaks/what-to-see-and-do-in-reims-champagne-06rg5qdnm","__typename":"Article"},"Image:15a0fca1-cc9e-4cf3-8950-59584dce7987":{"caption":"Reims is the walkable capital of the Champagne region","credits":"Alamy","title":"View of the Cathedrale Notre-Dame de Reims in Reims Here’s where to go","id":"456dc8e6-3a7b-4600-86cd-b55b279ef634","label":null,"publicationName":"TIMES","publishedTime":"2024-07-25T23:01:00.000Z","updatedTime":"2024-07-25T19:51:49.000Z","section":null,"shortIdentifier":"d53z0wttc","shortHeadline":"I’ve visited the Champagne region for 25 years Here’s where to go","seoDescription":"A new biopic has put this area of France — and the formidable woman behind the fizz — in the spotlight stay and pick up bargain bottles","slug":"ive-visited-the-champagne-region-for-25-years-heres-where-to-go","categoryPath":"/travel/destinations/europe-travel/france/ive-visited-the-champagne-region-for-25-years-heres-where-to-go-d53z0wttc","__typename":"Article","summary({\"maxCharCount\":105})":{"type":"json","json":[{"name":"paragraph","children":[{"name":"text","attributes":{"value":"The 17th-century monk Dom Pérignon gets the credit for refining champagne’s production but the bubbly 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walkable capital of the Champagne regionALAMYJanice HopperMonday January 27 2025 The Sunday TimesLess than an hour’s train ride from Paris St Remi Basilica in Notre Dame CathedralALAMYDay one• Morning: Pommery• Lunch: Le Réfectoire • Afternoon: Taittinger • Drink: Pol Couronne• Evening: Notre Dame Cathedral• Dinner: Café du Palais • Morning: Maison Fossier• Lunch: Case à Pain• Afternoon: Musée de la Reddition• Drink: Cuivré• Evening: Hautes Promenades • Dinner: Brasserie du Boulingrin The Maison de Champagne in PommeryALAMYWhat to do• It’s never too early to start sipping in Reims includes tasting; champagnepommery.com).• Taittinger is the region’s largest family-owned champagne house and one of the most laid-back includes tasting; taittinger.com).• Reims’ Unesco-listed Notre Dame Cathedral is a real gothic showstopper where 25 kings of France were crowned said to keep watch over the city (free; cathedrale-reims.com).• Stock up on sweet souvenirs at Maison Fossier drop by Fossier’s other shop on Jean-Baptiste Langlet (£4.50 for tour and tasting; fossier.fr).• Reims’ significant role in the end of the Second World War is commemorated in the Musée de la Reddition surrounded by details of casualty numbers and POW statistics exactly as it was on that fateful day (£4.50; musees-reims.fr).• Head to Hautes Promenades park to snap a pic in front of the Reims city sign Maison Fossier is the oldest biscuit producer in FranceALAMYWhere to eat and drinkLe RéfectoireSavour French classics in the smart but relaxed restaurant on Pommery’s estate including a slightly sweeter Pommery Blue Sky served over ice to accompany the peach melba (mains from £18; vrankenpommery.com) • 12 of the finest champagne houses in France Head to the centre of town to Pol Couronne’s Champagne Bar for a lesson in how to sabre a bottle of bubbles you can drink your spoils afterwards (£43; champagne-polcouronne.com) Café du Palais first opened in 1930ALAMYCafé du PalaisThis Reims institution is art deco in style and first opened in 1930 lardons and pommes grenailles is a hearty treat (mains from £14; cafedupalais.fr) The tarte au sucre (£2) is a must-buy (case-a-pain.fr) • 11 of the best cities to visit in France calf’s head stew and a range of tartares (mains from £13; boulingrin.fr) This article contains affiliate links that can earn us revenue Hôtel Azur Reims has 20 individually decorated roomsSmart budget offering with patioThis independent boutique hotel has 20 individually decorated rooms Non-residents are also welcome (room-only doubles from £62; hotel-azur-reims.com) Best Western Premier Hôtel De La Paix is great for familiesMICHAËL BOUDOTSuper central with an indoor pool tooBook contemporary accommodation across 163 rooms and a delicious ratafia baba (room-only doubles from £132; bestwestern-lapaix-reims.com) Domaine Les Crayères is renowned for its wine cellars and two-star Michelin restaurantANNE-EMMANUELLE THIONStay in a luxurious châteauAn elegant 1904 château and former house of the Polignac family a two-Michelin-star fine-dining restaurant under the chef Christophe Moret (room-only doubles from £405; lescrayeres.com) Reims is about 50 minutes from Paris/Charles de Gaulle airport by train alternatively hop on a bus/tram for £1.60 (grandreims-mobilites.fr) Become a subscriber and Sign up for the travel newsletter and follow us on Instagram and X "The first thing I would like to highlight is the success of this competition Reims already had a history of organising kata competitions Until last year this was done under the auspices of the European Judo Union It made sense for us to rely on local organisers because they already knew what needed to be done They have already expressed their desire to host another edition next year we are also working hard to get other continents involved we believe we can attract more and more participants We are thus providing them with a broader range of opportunities to better prepare for the world championships The Kata World Series is the antechamber to the world championships ‘practising in front of international judges is important.’ It allows them to assess their progress and their room for improvement Since the format is the same as at the world championships everything is in place for everyone to improve being able to participate in more competitions also allows them to develop a sense of belonging to a global circuit It gives them recognition at international tournaments I find that year after year we see more and more countries getting involved There is no doubt that the fruit of this development will be reaped at the next world championships The kata commission expects around 200 pairs The Reims IJF Kata World Series 2025 will help achieve this goal 2025 / On Monday 14th April 2025 the International Judo Federation .. 2025 / Koshiki-no-kata (古式の形) corresponds to the form .. 2025 / Follow the Reims IJF Kata World Series 2025 live on .. 2025 / The Tbilisi Grand Slam is a firm favourite on the IJF .. The Red and Whites (8-9-14) are traveling to Allianz Riviera in Nice France on Friday where they will take on Nice (15-9-7) Nice are priced at -196 and the Red and Whites are at +162 The starting goalkeepers are Marcin Bułka for Nice and Yehvann Diouf for Reims The Eagles have allowed 39 goals while giving up 1.26 goals per 90 min and their oppositition have 153 shots on target against them which puts them at a rate of 19.4% on the campaign Nice has amassed 56 yellow card warnings so far this year as well as 5 red cards The Eagles are 20th in relation to expected goals with 54.2 and the squad's expected goals against are 36.4 the team holds an average of 1.74 points per match (54 points) and they also are ranked 26th among European teams with 39 assists Their goal differential is currently at 20 by means of 59 goals earned and also 39 goals conceded Nice has accounted for 114 SVs and also have a save% of 74.5% on the campaign Get all of our Soccer Betting Picks The Red and Whites are averaging 1.1 pts/match while recording 18 assists and 6 red cards The Red and Whites have a shut out % of 22.6% so far this season and 62 yellow cards Reims ranks 42nd when talking about goals allowed with 42 and the team's goal differential is sitting at -10 the Red and Whites have a save rate of 75.0% (168 shots on target against) and they also are 74th in European soccer with 33 points The team's goals against per 90 minutes is at 1.35 in addition to 125 saves Reims has tallied 32 goals and the team's expected goals this season is 34.2 The man protecting the net for Nice will be Marcin Bułka Bułka has played for a total of 6,300 mins and has earned 200 saves in his pro soccer career His GA/90 is 1.03 (72 total goals allowed) and he is the owner of a save percentage of 73.0% The goalie born in Poland has seen 274 shots attempted at him in 70 starting assignments Bułka (31-20-19 record during his career) has earned 24 clean sheets which has earned him a 34.3%% clean sheet percentage Yehvann Diouf will be looking after the net for Reims Diouf has allowed 121 goals and has racked up 327 stops in 97 starting assignments Diouf has racked up 29 clean sheets and has defended 448 shots attempted against him in 8,775 mins in his career He is the owner of a save % of 73.0% and his clean sheet rate is currently at 29.7%% He has surrendered 1.24 goals per 90 while he holds a mark of 32-29-36 Evann Guessand is a member of the side you are going to want to keep your eye on for Nice Guessand has had a starting assignment in 94 matchups during his soccer career and tallies 0.31 goals per 90 minutes The forward from Côte d'Ivoire has totaled 31 goals in 9,046 professional minutes played He has 16 assists while earning 78 points so far in his career He has totaled 101 points in his pro soccer career and has helped on a goal 13 times The forward from Japan has been on the pitch for 9,784 mins while he has scored 44 goals He has an average of 0.40 goals per 90 and has been a starter in 115 matches in his career Who will win tonight's soccer game against the spread Josh Schonwald's Pick: Take Nice (+162) Get $60 worth of FREE premium member picks. No Obligation. No Salesman. No Credit Card. Fast Sign up with Instant Access Click Here Get all of Today's Free Soccer Picks Get all of Today's Expert Soccer Picks The French government has awarded Latitude funding to support the construction of its new rocket factory in Reims Latitude is developing a two-stage rocket called Zephyr designed to deliver payloads of up to 200 kilograms to low Earth orbit the company expects to produce between five and ten Zephyr rockets per year Latitude first announced plans to develop a larger rocket factory in late 2023, when it expanded its original site from 1,500 to 3,000 square metres The new facility is expected to span approximately 25,000 square metres and will support a production capacity of up to 50 Zephyr rockets per year Latitude announced that it had been awarded funding through the France 2030 “First Factory” call to assist with the construction of its new rocket factory the France 2030 initiative is a €54 billion investment programme aimed at strengthening French industry through technological innovation the country launched the “First Factory” call under the France 2030 initiative as a means of supporting start-ups and SMEs in establishing their first industrial production sites on French soil “This program consolidates our industrial vision: to develop a high-frequency launch capability for small satellites – a key lever of space sovereignty,” said Latitude Executive Chairman Stanislas Maximin Latitude did not disclose the exact amount of funding it received for the construction of its new factory it is known that while part of the funding will be awarded as a straight grant a portion will take the form of a recoverable loan Latitude is currently working toward an inaugural flight of its Zephyr rocket, which is expected to take place in 2026. On 8 April, the company announced that it had completed an initial hot fire test of a flight version of the combustion chamber for its Navier rocket engine at its Titan testing centre in Vatry Maximin announced on Twitter that the company had successfully completed a second test The Executive Chairman also revealed that Latitude is in the process of building a replica of its launch installation to allow the company to begin integrated tests of the Zephyr’s first and second stages at its Titan testing facilities Help European Spaceflight continue to go after stories that are too often overlooked How to Watch OGC Nice vs. Stade Reims: Live Stream, TV Channel, Start Time | 5/2/2025Data SkriveA game featuring two of Ligue 1's top scorers is coming up when Evann Guessand (10th) and OGC Nice meet Stade Reims and Keito Nakamura (10th) on Friday, May 2, 2025. Stream the match on Fubo Nice picked up a 3-1 victory away from home against Paris Saint-Germain while being outshot by 26 in the matchup Stade Reims drew 0-0 on the road against Montpellier HSC in its last game on April 27 Watch live sports and more without cable on FuboTV. Click here for a free trial A Universidade Federal de Pernambuco possui três campi: o do Recife distribuídos na capital e no interior do estado agregam 100 cursos de graduação presenciais regulares: 83 cursos de graduaçã.. consiste em um sistema informatizado gerenciado pelo MEC para seleção de candidatos a vagas em cursos de gra.. A Coordenação de Concursos Docentes tem como atribuição gerir atividades relacionadas aos concursos públicos de provas e títulos para cargos de magist.. A Universidade Federal de Pernambuco possui 100 cursos de graduação distribuídos nos campi do Recife A Universidade Federal de Pernambuco oferece à comunidade acadêmica uma série de cursos seqüenciais que são um conjunto de atividades sistemáticas de .. A produção científica da Universidade Federal de Pernambuco é considerada uma das melhores do Brasil Promover a convergência entre as competências tecnológicas da UFPE e as demandas da sociedade gerando parcerias e interações baseadas na confiança e .. UFPE © Copyright 2025 - Todos os direitos reservados to be forced wide and see his shot blocked The hosts suffered a setback midway through the first half as Deiver Machado was forced off through injury and replaced a few minutes later by the arguably more attack-minded Angelo Fulgini Almost immediately after Fulgini’s introduction, Jordan Siebatcheu will perhaps feel that he should have at least troubled Lens goalkeeper Mathew Ryan, as Junya Ito’s corner was headed over from close range by the American Reims did get their noses in front on 33 minutes, however, as patient build-up play resulted in Sergio Akieme seeing his cross inadvertently sent back to him by Lens defender Juma Bah, with Akieme duly cutting the ball back for Keito Nakamura to guide it into the roof of the net Lens - Reims match statsOpta by StatsPerformTo compound matters, Bah soon had to be withdrawn, having failed to sufficiently recover from a head knock sustained earlier in the half, with Malang Sarr taking his place Lens manager Will Still will have been looking for more attacking quality from his team heading into the second period, with nothing yet guaranteed. Indeed, an equaliser could have materialised less than a minute after the interval were it not for Hiroki Sekine’s block to thwart Sotoca whose downward header was stopped by Diouf before Koyalipou fired the rebound over Lens continued to threaten after that switch, with substitute Wesley Saïd’s poor control preventing him from getting on the scoresheet, before Yehvann Diouf pulled off a double save to deny Anass Zaroury and Adrien Thomasson The points were sealed late on, however, when a breakaway by Nhoa Sangui was stroked home by Nakamura for his second of the night and Reims ended their 13-game H2H winless streak the Sang et Or remain five points adrift of the top six Flashscore Man of the Match: Sergio Akieme (Stade de Reims) Check out all the match stats with Flashscore. ByLauren Mowery Forbes contributors publish independent expert analyses and insights and sustainable living.Follow AuthorDec 03 08:10pm ESTShareSaveComment@font-face{font-family: "Schnyder"; src: url("https://i.forbesimg.com/assets/fonts/schnyders/schnyders-bold-webfont.woff2") format("woff2") url("https://i.forbesimg.com/assets/fonts/schnyders/schnyders/schnyders-bold-webfont.woff") format("woff"); font-weight: 700; font-style: normal;} @font-face{font-family: "Merriweather"; src: url("https://i.forbesimg.com/assets/fonts/merriweather/merriweather-bold-webfont.woff2") format("woff2") url("https://i.forbesimg.com/assets/fonts/merriweather/merriweather-bold-webfont.woff") format("woff"); font-weight: 700; font-style: normal;} @font-face{font-family: "Euclid"; src: url("https://i.forbesimg.com/assets/fonts/euclidcircularb/euclidcircularb-bold-webfont.woff2") format("woff2") url("https://i.forbesimg.com/assets/fonts/euclidcircularb/euclidcircularb-bold-webfont.woff") format("woff"); 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Neue",Corbel,Helvetica,Arial,sans-serif;} #article-stream-0 .quote-embed.font-size p #article-stream-0 .quote-embed .font-size p{font-size: 36px;} Champagne Taittinger's legendary cellars Taittinger quietly welcomed guests back to its Saint-Nicaise site after an 18-month transformation The revamped space now offers an elevated experience complete with three new tours and tastings designed to showcase the essence of this celebrated Champagne house The house produces approximately 6 million bottles annually with about 73% destined for export markets While Taittinger doesn’t compete on volume or value with other brands the American market bestows upon it a reputation for quality and heritage its release of one of the best blanc de blancs Champagnes The new visitor center has clean lines and modern decor traces its origins to the 13th-century Saint-Nicaise Abbey in Reims known as 'crayères,' are ancient chalk quarries dating back to the Gallo-Roman era The stone from these quarries built the city of Reims Champagne houses discovered that these subterranean galleries provided the ideal environment for aging bubbles due to their consistent temperature and humidity levels the crayères served as shelters for the denizens of Reims with makeshift communities developing to maintain a semblance of everyday life below the city’s chaotic streets a school named for General Augustin Dubail was established to ensure the continuation of education for the city's children the crayères of Saint-Nicaise Hill were designated as a UNESCO World Heritage Site recognizing their historical significance and unique contribution to the Champagne region's heritage Taittinger is one of seven historical Champagne houses that still own and utilize chalk cellars in the hill Though Épernay has long drawn tourists and oenophiles to its famous Avenue de Champagne a hallowed street on which some of the region's most prestigious champagne houses call home The city is only 45 minutes by train from Paris alleviating the need to rent a car from the French capital The city lures visitors with its upscale hotels Taittinger temporarily closed its Saint-Nicaise visitor center to undergo renovations the house hosted tastings at its Demeure des Comtes de Champagne venue in central Reims Moving tastings to another location – instead of pausing them – allowed the house to experiment with audio-guided tours and sensory experiences that delved deeper into the stories behind their blends the newly redesigned visitor center reopened in July 2024 revealing a striking new look that was more in line with the artistic ethos of the brand contemporary space infuses French flair through the furnishings from arches and curves to fluted glass doors and cabinetry trimmed in black the rooms and lounges remain accessible to all whether Champagne neophytes or seasoned consumers With a focus on smaller, more intimate groups, Taittinger now offers three experiences This 70-minute tour provides an introduction to Taittinger's point of view Guests explore the cellars before enjoying tastings of the Brut Réserve and Prestige Rosé Champagnes This 90-minute experience highlights the interplay between Champagne and food guests sit down of hors d'oeuvres designed by Philippe Mille a well-known chef from Reims who has received two Michelin stars for his work at Le Parc restaurant in Domaine Les Crayères Guests pair bites with Prestige Rosé and Vintage Brut bubbles to showcase how flavors in food complement different styles of Champagne this 105-minute journey takes guests on a deep dive into Taittinger's history and production methods guests explore three Champagnes with their guide These tours educate guests on the history of the crayères and the Champagne production process while emphasizing Taittinger's brand of hospitality Taittinger will expand the visitor center again with the addition of a restaurant and bar The menu will feature refined French cuisine paired with Taittinger bubbles Pick up a bottle or sleek gift from the retail shop on the way out extending their unbeaten streak against them to 13 games boosting Nice's Champions League hopes while Reims remain safe from relegation OGC Nice secured a hard-fought 1-0 victory over Stade de Reims at the Allianz Riviera extending their unbeaten head-to-head record against Les Stadistes to an impressive 13 matches This nervy win keeps Nice firmly in the hunt for an automatic UEFA Champions League spot next season Coming off a historic 3-1 victory against Paris Saint-Germain – the first Ligue 1 defeat for PSG this season – Nice were brimming with confidence They knew a win before their rivals played this weekend would put significant pressure on the chasing pack scoring his third goal in that short span to give Nice the lead after 15 minutes a fortunate deflection following a chipped ball into the box was the highlight of a first half lacking in significant goal-scoring opportunities for both teams spurred by their manager Franck Haise's pre-match declaration of their team’s potential created several dangerous chances in the second half Valentin Atangana had a gilt-edged opportunity but his shot sailed over the bar The win lifts them provisionally into third place five points clear of the relegation zone with two games left Morgan Sanson was named Flashscore Man of the Match for his decisive goal and impactful performance Reims’ Keito Nakamura also missed a clear opportunity to equalize The match highlights the contrasting fortunes of the two teams: Nice's Champions League ambitions versus Reims' fight for survival Nice's victory underscores their strong late-season form and their determination to secure a top-three finish Their unbeaten run against Reims continues a testament to their dominance in this fixture the focus shifts to securing their Ligue 1 status for next season Morgan Sanson scored the only goal of the game securing a crucial 1-0 victory for OGC Nice against Stade de Reims His strike proved to be the difference-maker in a closely fought match Nice extended their unbeaten streak against Reims to an impressive 13 games with this victory This dominant run highlights the significant disparity in form between the two teams in recent encounters The win significantly boosts Nice's hopes of qualifying for the Champions League It puts them in a stronger position in the Ligue 1 standings closing the gap on the top teams and keeping their European dreams alive they maintain a comfortable position in the Ligue 1 table The full match report detailing the game between Nice and Reims can be found on [Insert Link to Match Report Here] You can also find highlights and more detailed analysis of the game All trademarks are the property of their respective owners All rights reserved @ 2025 Nishtya Infotech (India) Ltd Celtic forward Daizen Maeda scored his 30th goal across all competitions this season in Scotland on Saturday while his Japan teammate Keito Nakamura got a goal and assist as Reims ended their 15-game winless run in France Maeda bagged a brace in a 3-0 home win over Hearts in the Premiership beginning with a 17th-minute opener at Celtic Park where he calmly side-footed into the far corner after Callum McGregor played him through but Jota slotted home the rebound for their second in the 24th minute before the Japanese speedster tapped in Nicolas Kuhn's pass across the face of the goal to complete the scoring in the 41st minute Nakamura got his ninth goal in Ligue 1 this term during Reims' huge 3-1 home win over Marseille grabbing a 29th-minute opener after creating a little gap inside the box before firing home Reims doubled the lead following a 51st-minute counter launched by Japan winger Junya Ito with Nakamura setting up Mamadou Diakhon to squeeze home and while Valentin Rongier's stunner pulled one back for the visitors the home team secured vital points to ease their relegation fears substitute Daichi Kamada assisted Eddie Nketiah for the last goal of Crystal Palace's 3-0 win at Fulham in the FA Cup quarterfinals Kaoru Mitoma came off as Brighton went out at home to Nottingham Forest losing 4-3 in a penalty shootout after a 0-0 draw Shunsuke Mito netted a double in Sparta Rotterdam's 3-0 win at Fortuna Sittard as the attacker took his season's tally to five goals Forward Kento Shiogai came on and scored to help NEC Nijmegen secure a 3-3 home draw with AZ Alkmaar Football: World Cup-bound Japan held 0-0 at home by Saudi Arabia Judo: 66-kg Olympic champion Hifumi Abe to return at open-weight c'ships Snowboarding: Murase, Kimata win as Japan dominates big air at worlds Wolverhampton Wanderers have confirmed the signing of defender Emmanuel Agbadou from Ligue 1 club Stade de Reims The Athletic reported on Monday that Wolves had agreed to a fee of €18million (£14m; $18.8m) plus €2m in add-ons for Agbadou. The centre-back underwent a medical on Monday and has signed a four-and-a-half-year contract with the Premier League club The deal also contains an option for a further 12 months Wolves have been looking to bolster their defence after the departure of former captain Maximilian Kilman to West Ham United in July and the anterior cruciate ligament injury (ACL) suffered by Yerson Mosquera in September Agbadou’s arrival gives new head coach Vitor Pereira — who replaced Gary O’Neil in December — more options in his favoured back three and is the club’s first signing under the Portuguese The 27-year-old is an Ivory Coast international and has been capped 11 times He had made 15 appearances for Reims in all competitions this season “Emmanuel’s a winner and he’s driven,” Wolves sporting director Matt Hobbs told the club’s website He’s the type of player the Wolves fans should love because you’re going to get absolutely everything he’s got but he can fall back on his key attributes being akin to the Premier League “The fact that he was on ours and Vitor’s lists shows that he’s well rounded Then being made captain of Reims has really taken his game to the next level Agbadou joined Reims from Belgian Pro League club Eupen in 2022 one place above the relegation zone after Monday’s 3-0 home defeat against Nottingham Forest and only ahead of 18th-placed Ipswich Town on goal difference The West Midlands side have conceded a league-high 45 goals this season who have previously been deployed as full-backs or wing-backs have been used as part of the three-man defence amid Wolves’ limited options at centre-back Agbadou could be in line to make his debut on Saturday when Wolves begin their FA Cup campaign with a visit to Championship side Bristol City (Top photo: Francois Nascimbeni/Getty Images) Reims Boost PSG's Title Hopes with Stunning Win Over MarseilleStade de Reims pulled off a crucial 3-1 victory over Olympique de Marseille on Matchday 27 of Ligue 1 a result that not only lifts them further from the relegation zone but also brings Paris Saint-Germain to the brink of clinching the title Reims snapped a 15-match winless streak in the league and now sit five points clear of the drop the result means that PSG could mathematically secure the Ligue 1 title this Saturday if they defeat Saint-Étienne and Monaco vs Nice ends in a draw when Keito Nakamura opened the scoring with a composed finish following an assist from Mamadou Diakhon Diakhon then doubled the lead in the 52nd minute capitalizing on Marseille's disorganized defense Valentin Atangana Edoa added a third for Reims Valentin Rongier managed a late consolation goal for Marseille but it wasn’t enough to prevent a third straight league loss for the visitors The loss leaves Marseille second in the table trailing PSG by 19 points and holding just a two-point lead over Monaco and Nice who are in pursuit of European qualification PSG now have a golden opportunity to secure the title early If Luis Enrique’s men defeat Saint-Étienne the Parisian giants will officially be crowned Ligue 1 champions Not only did they take down a top-tier opponent but they also rediscovered their attacking flair and intensity at a critical point in the season Metrics details A rapid and real-time method was established based on the combination of rapid evaporative ionization mass spectrometry (REIMS) and two-dimensional liquid chromatography mass spectrometry (2DLC-MS) for identification of wild Astragali Radix (WAR) and cultivated AR (CAR) The samples were analyzed under ambient ionization without time-consuming sample preparation The phenotypic data of WAR and CAR were used to develop a real-time recognition model the compounds in these two species were comprehensively characterized based on 2DLC-MS and 45 different compounds were screened out by multivariate statistical analysis A semi-quantitative method for 45 different compounds was established based on ultrahigh-performance liquid chromatography/quadrupole-linear ion trap mass spectrometry (UHPLC-QTRAP-MS) The results showed that the relative content of most compounds in WAR was higher than in CAR the method has demonstrated remarkable performance in distinguishing between WAR and CAR providing a reference in the field of traditional Chinese medicine (TCM) analysis and identification it is of great significance to establish a rapid and effective method for identifying WAR and CAR such as the need for cumbersome sample preparation and time-consuming instrument operation these techniques can not fully characterize the samples leading to insufficient discrimination accuracy given the compositional complexity of most herbal metabolites the aforementioned single analytical method is not sufficient to completely characterize complex components and trace components an integrated strategy combining different MS instruments could provide a solid foundation for the systematic characterization and annotation of the chemical diversity of TCM The present study aimed to develop a method that could rapidly and accurately distinguish between WAR and CAR based on REIMS combined with 2DLC-MS technology REIMS was used to establish a discriminant model to identify unknown AR samples in the market thereby enabling accurate distinction of the two types many batches of AR samples were characterized by 2DLC-MS and potential markers were screened by multivariate statistical analysis to further verify the REIMS results a QTRAP-MS platform was used to further screen potential markers and conduct semi-quantitative analysis the REIMS method was developed to identify WAR and CAR in real time without any sample preparation This study provides a rapid and almost nondestructive method for the qualitative detection of TCMs that are easily confused It was found that the overall intensity of the total ion chromatograms (TICs) increased from 30 V to 55 V resulting in the maximum signal intensity at a heater bias voltage of 55 V 40 V and 55 V were chosen as the optimal cone voltage and heater bias voltage c The mass spectra of WAR in the range of m/z 100–1000 d The mass spectra of CAR in the range of m/z 100–1000 c Bidimensional score lots along the first two main linear discriminants e Loading plot relative to the PC2 (explaining 32.48% and 8.38% of the total variance of the model) f Real-time recognition by LiveID of WAR in the mutivariate model g Real-time recognition by LiveID of CAR in the mutivariate model A total of eight unknown samples were identified in real-time; samples U1-U4 were identified as WAR Recognition confidence for both WAR and CAR samples was above 99% The results demonstrated that the REIMS-based method is also feasible and suitable for identifying WAR and CAR samples REIMS eliminates the need for sample pretreatment It takes only a few seconds to complete data collection and analysis avoiding the time-consuming analysis of traditional LC-MS it can also generate information at the molecular level and it is possible to identify different metabolite ions to distinguish medicinal materials It provides a new approach for the analysis and identification of WAR and CAR c Results of 100 permutation tests of OPLS-DA The relative contents of these two saponins were higher in WAR compared to CAR making WAR more advantageous for clinical applications contrasting with the 35.31 ± 7.59 found in CAR It may have application advantages in clinical application of WAR to treat diseases pronounced differences exist in the content of compounds between WAR and CAR attributed primarily to variations in tissue structure and cell composition as well as differences in cultivation methods and growth environments the REIMS method was developed for the direct analysis of WAR and CAR samples combining 2DLC-MS and multivariate statistical model The proposed REIMS method could rapidly distinguish unknown AR samples with an accuracy of 99% Through 2DLC-MS and multivariate statistical analysis 45 different compounds were screened out and identified based on the semi-quantitative analysis platform of UHPLC-QTRAP MS a semi-quantitative method for 45 different compounds in WAR and CAR was established which could be considered as significantly differential metabolites between the two species The results showed that the relative content of most compounds in WAR was higher than that in CAR the REIMS technique is a promising tool for low conductivity sample ionization and MS profiling without sample preparation The strategy of this study not only provides an objective method for identifying WAR and CAR but also provides a reference for the identification of other medicines with the same origin so as to ensure the safety and effectiveness of their clinical use These samples were subjected to authentication by Professor Pengfei Tu (Peking University and perform further confirmation based on microscopic structures All these samples were deposited at the authors’ laboratory (Peking University The sample was crushed and passed through a 50-mesh sieve. 1.0 g of powder was accurately weighed and added to 1.5 mL of water for dissolution, so that the sample became a certain viscous state, and the dissolved sample was placed into a cylindrical container wrapped with aluminum foil for testing, as shown in Fig. S5 Each batch of AR powder (1.0 g) was thoroughly mixed together to make a QC sample for the optimization of the REIMS experimental conditions Accurately weighed AR powder (500 mg) was placed into 15 mL centrifuge tubes containing 10 mL of 70% methanol (v/v) Then the samples were ultrasonic extracted for 1 h followed by centrifugation at 10,000 rpm for 10 min and the supernatant was passed through a 0.22 μm polytetrafluoroethylene (PTFE) membrane to be detected by 2DLC-MS A QC sample was prepared by mixing equal volumes of each AR sample to evaluate the performance of the 2DLC-MS system All sample solutions were stored in a refrigerator at 4 oC before use The REIMS analysis was performed using a REIMS ion source coupled to a Waters Xevo G2-XS quadrupole time-of-flight mass spectrometer (Waters a monopolar electrosurgical knife (Model PS01-63H China) device was used to apply localized high-frequency current to the surface of the samples through a 3 m long 1 cm diameter ultra-flexible tubing (evacuation/vent line) Electrosurgical dissection in all experiments was performed using an Erbe VIO 50 C generator (Erbe Medical UK Ltd and the aerosols containing gaseous compounds were aspirated through a PTFE tube attached to a venturi gas jet pump that is attached to the REIMS source described above The ionization conditions of the iKnife were optimized as follows: heater bias voltage: 55 V; cutting time: 1 S; cutting length: 1 cm; cone voltage: 40 V Ten technical replicates were carried out per sample with 2–3 s delay between each cut 0.1% formic acid-50% acetonitrile/water (v/v) of leucine enkephalin solution (200 pg/μL) was used as a lock mass solution and continuously introduced at a flow rate of 2 µL/min The mass spectra were acquired in negative ion mode with the mass range of m/z 50–1200 USA) was used for REIMS data acquisition and peak extraction and all MS data was collected in negative ion mode The mass spectra signals of 10 peaks were taken from each sample to build a model Data analysis was completed by LiveID 1.2 software (Waters The setting parameters for “Build the model” in Live ID are as follows: five PCA components; one linear discriminant; three standard deviations; binning resolution of 0.1 m/z; mass range of 50–1200 m/z Using the default Leu-Enk setting for the demonstration data peak extraction and alignment were achieved using MS-DIAL 5.1.230912 software The setting parameters related to data processing by MS-DIAL software are as follows: MS1 tolerance 1000 amplitude; mass slice width: 0.1 Da; retention time tolerance The compounds were identified by molecular formula prediction online database retrieval (ChemSpider/PubChem) and confirmation using the “assign” function in Insight Explore software (Shimadzu MetaboAnalyst 6.0 was used for statistical analysis including principal component analysis (PCA) and orthogonal partial least squares discriminant analysis (OPLS-DA) The related parameters settings are as follows: missing value estimation remove features with >50 missing values; sample normalization supervised OPLS-DA analysis was used to visualize the variable difference between two groups and 100 permutation test was conducted to avoid over-fitting of OPLS-DA model Metabolites with a variable importance to the projection value (VIP) > 1.5 and p-value (p) < 0.05 were considered as differential metabolites The raw QTRAP data was controlled and analyzed by Analyst 1.6.2 (AB SCIEX All data generated or analysed during this study are included in this published article and its supplementary information files and pharmacology of Astragalus membranaceus (Huangqi) Astragali Radix (Huangqi): a promising edible immunomodulatory herbal medicine and biological activity of astragali radix Study on genetic diversity of Astragalus membranaceus var Quality analysis of semi-cultivated Astragalus membranaceus var mongholicus from Hunyuan County of Shanxi Province Recent advances in spectroscopic techniques for the analysis of microplastics in food Liquid Chromatography-Mass Spectrometry (LC-MS)-based analysis for lipophilic compound profiling in plants Human biomonitoring of environmental and occupational exposures by GC-MS and gas sensor systems: a systematic review LC-MS/MS determination of 21 non-steroidal anti-inflammatory drugs residues in animal milk and muscles Nontargeted screening method for illegal additives based on ultrahigh-performance liquid chromatography-high-resolution mass spectrometry Chitosan nanoparticles modified TLC-densitometry for determination of imidacloprid and deltamethrin residues in plants: greenness assessment Identification strategy of Fructus Gardeniae and its adulterant based on UHPLC/Q-orbitrap-MS and UHPLC-QTRAP-MS/MS combined with PLS regression model Integrated widely targeted metabolomics and network pharmacology revealed quality disparities between Guizhou and conventional producing areas of Codonopsis Radix Intraoperative tissue identification using rapid evaporative ionization mass spectrometry Matrix assisted rapid evaporative ionization mass spectrometry Differentiation between fresh and frozen-thawed meat using rapid evaporative ionization mass spectrometry: the case of beef muscle Real-time in situ screening of Omega-7 phospholipids in marine biological resources using an iknife-rapid-evaporative-ionization-mass-spectrometry-based lipidomics phenotype Rapid evaporative ionization mass spectrometry-based lipidomics for identification of canine mammary pathology The surgical intelligent knife distinguishes normal borderline and malignant gynaecological tissues using rapid evaporative ionisation mass spectrometry (REIMS) Rapid evaporative ionisation mass spectrometry of electrosurgical vapours for the identification of breast pathology: towards an intelligent knife for breast cancer surgery Laser-assisted rapid evaporative ionisation mass spectrometry (LA-REIMS) as a metabolomics platform in cervical cancer screening Detection of lipidomics characterization of tuna meat during different wet-aging stages using iKnife rapid evaporative ionization mass spectrometry Multivariate versus machine learning-based classification of rapid evaporative Ionisation mass spectrometry spectra towards industry based large-scale fish speciation Real-time authentication of minced shrimp by rapid evaporative ionization mass spectrometry Rapid evaporative ionization mass spectrometry (REIMS) combined with chemometrics for real-time beer analysis Separation and detection of minor constituents in herbal medicines using a combination of heart-cutting and comprehensive two-dimensional liquid chromatography A simple way to configure on-line two-dimensional liquid chromatography for complex sample analysis: acquisition of four-dimensional data Application of two-dimensional liquid chromatography in the separation of traditional Chinese medicine Identification and characterization of quinoline alkaloids from the root bark of Dictamnus dasycarpus and their metabolites in rat plasma urine and feces by UPLC/Qtrap-MS and UPLC/Q-TOF-MS Pseudotargeted metabolomics approach enabling the classification-induced ginsenoside characterization and differentiation of ginseng and its compound formulation products Pseudotargeted metabolomics-based random forest model for tracking plant species from herbal products A multidimensional chromatography/high-resolution mass spectrometry approach for the in-depth metabolites characterization of two Astragalus species Astragaloside II alleviates the symptoms of experimental ulcerative colitis in vitro and in vivo Astragaloside VI promotes neural stem cell proliferation and enhances neurological function recovery in transient cerebral ischemic injury via activating EGFR/MAPK signaling cascades Download references This work was supported by the National Key R&D Program of China (No and the National Natural Science Foundation of China (No State Key Laboratory of Natural and Biomimetic Drugs The authors declare no competing interests Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Download citation DOI: https://doi.org/10.1038/s41538-024-00333-3 Anyone you share the following link with will be able to read this content: a shareable link is not currently available for this article Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology Feature Films Database Southern Mediterranean films database Scriptwriters European Film Schools Production Companies Distributors International Sales Submit a Film Industry Reports Co-Production 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Advertise on Cineuropa Logos and Banners FESTIVALS / AWARDS France by Fabien Lemercier 07/04/2025 - The film by German director Jan Ole Gerster has won the Grand Prize; Little Jaffna The Things You Kill and We Believe You also stand out amongst the winners Unveiled last February as a special screening in Berlin, this English-language film whose story takes place on the Spanish island of Fuerteventura, stars Sam Riley, Stacy Martin and Jack Farthing amongst others. Sold internationally by Protagonist Pictures, Islands will be distributed in France by Jour2Fête Grand PrizeIslands [+see also: film reviewfilm profile] - Jan Ole Gerster (Germany) Police PrizeLa infiltrada [+see also: trailerfilm profile] - Arantxa Echevarría (Spain) Critics’ PrizeThe Things You Kill - Alireza Khatami Audience AwardLittle Jaffna - Lawrence Valin New Blood PrizeWe Believe You [+see also: film reviewtrailerinterview: Arnaud Dufeys and Charlotte…film profile] - Charlotte Devillers and Arnaud Dufeys (Belgium) New Blood Exceptional Best Acting AwardMyriem Akheddiou - We Believe You New Blood awarded by the Grand Est Region Youth JuryWe Believe You - Charlotte Devillers and Arnaud Dufeys Claude Chabrol PrizeThe Kingdom [+see also: film reviewtrailerinterview: Julien Colonnafilm profile] – Julien Colonna (France) Please subscribe to our newsletter to receive more stories like this directly in your inbox 05/05/2025Festivals / Awards – Czech Republic Czech Republic’s Anifilm goes sci-fi 05/05/2025HOFF 2025 The Shadow and U Are the Universe win at Estonia’s Haapsalu Horror and Fantasy Film Festival 05/05/2025Crossing Europe 2025 – Awards The New Year That Never Came and The Flats crowned at Crossing Europe 30/04/2025Cannes 2025 16 works to be presented in the Immersive Selection at Cannes 30/04/2025Festivals / Awards – Romania The New Year That Never Came sweeps the Romanian Gopos 30/04/2025goEast 2025 – Awards Holy Electricity comes out on top at goEast Subscribe to our newsletter to receive the most important daily or weekly news on European cinema Cannes 2025 Marché du Film AFCI runs its second annual Global Film Commission Network Summit at Marché du Film Festivals / Awards Czech Republic Distribution / Releases / Exhibitors Europe European Arthouse Cinema Day set to return on 23 November Cannes 2025 Marché du Film Indie Sales presents a three-star line-up at Cannes HOFF 2025 Crossing Europe 2025 Awards Cannes 2025 Marché du Film Be For Films to sell Love Me Tender in Cannes Cannes 2025/Sponsored Latvia set to shine bright at Cannes, led by Sergei Loznitsa’s competition entry Two Prosecutors Las Palmas 2025 MECAS/Awards Manuel Muñoz Rivas and Joana Carro win awards at the eighth MECAS Cannes 2025 Marché du Film Playtime to present some high-impact and entrancing trump cards at Cannes Production / Funding Italy Shooting begins on Walter Fasano’s Nino, a portrait of scoring maestro Nino Rota goEast 2025 Review: My Magical World Market TrendsFOCUSA busy spring festival season awaits the European film industry. Cineuropa will continue to keep its readers up to date with the latest news and market insights, covering the buzziest events, including Cannes, Kraków, Karlovy Vary, Tribeca, Hot Docs, Annecy, Brussels, Munich and many others Distribution, Exhibition and Streaming – 02/05/2025Slovak crime-thriller Černák becomes the highest-grossing film in domestic cinemasThe second film in the saga about a local mafia boss, directed by Jakub Króner, outgrossed its first part, which dominated Slovak cinemas last year Animation – 30/04/2025Mirko Goran Marijanac • Media sales executive, DeAPlaneta EntertainmentDuring our chat, the exec shared key insights from this year’s Cartoon Next and touched on the current climate for the animation sector Jaśmina Wójcik • Director of King Matt the First The Polish director discusses her approach to taking on a 1920s children’s literary classic in an unexpected way Želimir Žilnik • Director of Eighty Plus The Serbian director discusses his deep suspicion of ideologies in relation to his irresistibly charming latest feature, which follows a man whose life spans three political systems Paulina Jaroszewicz • Distribution and marketing manager, New Horizons Association Cineuropa sat down with the Polish distributor to discuss her company’s strategy as well as the connection between its distribution line-up and BNP Paribas New Horizons Festival’s programme Lorcan Finnegan • Director of The Surfer The Irish filmmaker discusses his mystery-thriller, how he created the character with Nicolas Cage and his approach to the use of colours in the film Privacy Policy The images used on this website have been provided by journalists and are believed to be free of rights if you are the owner of an image used on this website and believe that its use infringes on your copyright We will remove the image in question as soon as possible We have made reasonable efforts to ensure that all images used on this website are used legally and in accordance with copyright laws About us | Contact us | Logos and Banners Mission | Partners | Team | Donations | Terms and conditions Reims clung on for a 2-1 victory at fourth-division Cannes on Wednesday to set up a French Cup final meeting with holders Paris Saint-Germain in May. Cannes were looking to become the first fourth-tier club to reach the final since Calais lost to Nantes in the 2000 showpiece, but came up just short. Instead Ligue 1 side Reims moved to within one win of lifting their first major trophy since the 1991 French League Cup. They will face PSG, who came from two goals down to defeat second-tier Dunkerque 4-2 on Tuesday, at the Stade de France on May 24. Reims took a 14th-minute lead when Mamadou Diakhon powered to the byline and pulled the ball back for his fellow 19-year-old Hafiz Ibrahim to turn the ball into an empty net. Cannes pushed forward in search of an equaliser but almost fell two goals down before the half-hour mark when Reims countered from a corner, but Keito Nakamura could only drag his shot narrowly wide. The hosts were dreaming of the final, though, when captain Cheikh N'Doye levelled seven minutes after half-time. The 39-year-old former Senegal midfielder rose highest at the back post to head home Cedric Goncalves' corner. But Reims restored their advantage before the hour mark, Ibrahim teeing up substitute Teddy Teuma to score. Cannes piled on the pressure, but Reims held on to keep their hopes of a third French Cup title, and first since 1958, alive. Ousmane Dembélé opened the score for PSG on an assist from the Georgia international but saw Nakamura put both teams level less than 10 minutes later Paris was held to a 1-1 draw against Reims at the Parc des Princes in Khvicha Kvaratskhelia's debut for the club Paris hosted Stade de Reims at the Parc des Princes for Matchday 19 of the Ligue 1 McDonald's just three days after their incredible Champions League success against Pep Guardiola's Manchester City It was the perfect opportunity to see Kvaratskhelia make his official debut for the club Luis Enrique made many changes in his starting lineup with Hakimi and Marquinhos not involved in the squad Paris struggled to create much danger on Diouf's goal in the first 20 minutes of the game the Reims' keeper was proved to be important with numerous decisive saves that prevented the French champions to open the score as the first half ended goalless Just two minutes after the start of the second half Kvaratskhelia provided his first assist as a PSG player to Ousmane Dembélé who scored for the eighth times in his last seven games Reims equalised through Nakamura after a superb counterattack started with the keeper Playing in a different position in this game Mendes was more defensively solicited in his duel with Ito Solid perfomance from the former Rennes player Kvaratskhelia made his awaited PSG debut at the Parc des Princes after his transfer from Napoli last week The Georgian displayed flashes of his talent and will without a doubt become an important figure for the club in the upcoming weeks He nevertheless will need to build more chemistry with his teammates He was subbed off at the 83rd minute for Asensio Gonçalo Ramos looked to reiterate the same form he has when coming off the bench the Portuguese failed to score and was well covered by Reims centre back pair He was replaced by Senny Mayulu at the 73rd minute Dembélé showed once more that he is PSG's main offensive threat He was a constant worry for Reims' defender and put Diouf in danger many times His goal came from an assist from Kvaratskhelia on a good link up play and with this duo showing to be promising H was replaced by Barcola at the 60th minute © 2025 Minute Media - All Rights Reserved The content on this site is for entertainment and educational purposes only Betting and gambling content is intended for individuals 21+ and is based on individual commentators' opinions and not that of Minute Media or its affiliates and related brands All picks and predictions are suggestions only and not a guarantee of success or profit If you or someone you know has a gambling problem crisis counseling and referral services can be accessed by calling 1-800-GAMBLER Paris Saint-Germain and Stade de Reims split the points at the Parc des Princes 1-1 in Kvaratskhelia's debut for the club on Matchday 19 of the Ligue 1 McDonald's