Invivyd (Nasdaq: IVVD) has appointed venture capitalist Ajay Royan to its Board of Directors is a significant long-term stockholder who led the 2022 shareholder action focusing Invivyd on protecting against viral infectious diseases The company aims to advance its monoclonal antibody technology platform beyond COVID-19 prevention into more scalable The platform specifically targets vulnerable populations including cancer patients Royan emphasizes the need to address endemic diseases affecting vulnerable Americans with the same urgency as Operation Warp Speed highlighting the limitations of vaccines and the impact of long COVID on these communities Invivyd (Nasdaq: IVVD) ha nominato il capitalista di rischio Ajay Royan nel suo Consiglio di Amministrazione è un importante azionista a lungo termine che ha guidato l'azione dei soci nel 2022 concentrando Invivyd sulla protezione contro le malattie infettive virali L'azienda mira a sviluppare la sua piattaforma tecnologica degli anticorpi monoclonali oltre la prevenzione del COVID-19 verso medicinali più scalabili e di maggior valore La piattaforma si rivolge specificamente a popolazioni vulnerabili individui immunodeficienti e coloro che seguono terapie immunosoppressive Royan sottolinea la necessità di affrontare le malattie endemiche che colpiscono gli americani vulnerabili con la stessa urgenza di Operation Warp Speed evidenziando i limiti dei vaccini e l'impatto del long COVID su queste comunità Invivyd (Nasdaq: IVVD) ha nombrado al capitalista de riesgo Ajay Royan en su Junta Directiva es un importante accionista a largo plazo que lideró la acción de los accionistas en 2022 enfocando a Invivyd en la protección contra enfermedades infecciosas virales La empresa tiene como objetivo avanzar su plataforma de tecnología de anticuerpos monoclonales más allá de la prevención del COVID-19 hacia medicamentos más escalables y de mayor valor La plataforma se dirige específicamente a poblaciones vulnerables individuos inmunodeprimidos y aquellos en terapias inmunosupresoras Royan enfatiza la necesidad de abordar las enfermedades endémicas que afectan a los estadounidenses vulnerables con la misma urgencia que la Operación Warp Speed destacando las limitaciones de las vacunas y el impacto del long COVID en estas comunidades Invivyd (Nasdaq: IVVD)는 벤처 자본가 Ajay Royan을 이사회에 임명했습니다 2022년 주주 행동을 이끌며 Invivyd가 COVID-19를 포함한 바이러스 감염 질병 보호에 집중하게 만든 중요한 장기 주주입니다 회사는 단클론 항체 기술 플랫폼을 COVID-19 예방을 넘어 더 확장 가능하고 가치가 높은 의약품으로 발전시키는 것을 목표로 하고 있습니다 면역 결핍 개인 및 면역 억제 요법을 받는 사람들을 포함한 취약한 인구를 특히 겨냥합니다 Royan은 취약한 미국인들에게 영향을 미치는 풍토병을 해결해야 할 필요성을 Operation Warp Speed와 같은 긴급성으로 강조하며 Invivyd (Nasdaq: IVVD) a nommé le capital-risqueur Ajay Royan à son conseil d'administration est un actionnaire important à long terme qui a dirigé l'action des actionnaires en 2022 en concentrant Invivyd sur la protection contre les maladies infectieuses virales L'entreprise vise à faire avancer sa plateforme technologique d'anticorps monoclonaux au-delà de la prévention du COVID-19 vers des médicaments plus évolutifs et de plus grande valeur La plateforme cible spécifiquement les populations vulnérables les individus immunodéprimés et ceux sous traitements immunosuppresseurs Royan souligne la nécessité de traiter les maladies endémiques affectant les Américains vulnérables avec la même urgence que l'Opération Warp Speed mettant en évidence les limites des vaccins et l'impact du long COVID sur ces communautés Invivyd (Nasdaq: IVVD) hat den Risikokapitalgeber Ajay Royan in seinen Vorstand berufen ist ein bedeutender langfristiger Aktionär um Invivyd auf den Schutz vor viralen Infektionskrankheiten seine Plattform für monoklonale Antikörpertechnologie über die Prävention von COVID-19 hinaus zu erweitern und in skalierbarere Die Plattform richtet sich speziell an gefährdete Bevölkerungsgruppen mit derselben Dringlichkeit wie Operation Warp Speed anzugehen und hebt die Grenzen von Impfstoffen sowie die Auswirkungen von Long COVID auf diese Gemeinschaften hervor (Nasdaq: IVVD) is pleased to announce the appointment of Ajay Royan to its Board of Directors Royan is a venture capitalist focused on transformational companies that have solved critical problems in healthcare is a significant long-term holder of Invivyd stock Royan led the 2022 shareholder action that focused Invivyd on its mission to deliver protection from serious viral infectious diseases “We are delighted by Ajay’s return to the Board of Invivyd as the company prepares to take the next step forward in scaling the medical benefit from its core technologies Invivyd has rapidly re-established the field of monoclonal antibody prevention of COVID-19 and intends to advance into more scalable higher value medicines that can protect Americans from COVID-19 and other diseases Invivyd will benefit substantially from Ajay’s acumen as we move forward,” commented Marc Elia “Invivyd is an important company for the future of American medicine The monoclonal antibody technology platform unique to Invivyd transcends the limits of vaccination to provide high-quality best-in-class medicines for vulnerable populations,” said Ajay Royan “Endemic diseases affecting our country’s most vulnerable need to be attacked with the same alacrity and rapid impact that characterized President Trump’s Operation Warp Speed This is the clarity and urgency with which I and Invivyd look forward to working with critical partners both in industry and the new administration to rapidly deliver innovative monoclonal antibody therapies to patients who need them most – people living with cancer and individuals on immunosuppressive therapies COVID-19 continues to kill and disable vast numbers of vulnerable Americans for whom the limitations of vaccines and the burdens of long COVID are all too real And yet they have received neither their due voice in the media mainstream nor the urgent relief they deserve We can—and therefore must—address their growing unmet medical need with a holistic approach backed by proven American technology.” (Nasdaq: IVVD) is a biopharmaceutical company devoted to delivering protection from serious viral infectious diseases Invivyd deploys a proprietary integrated technology platform unique in the industry designed to assess and adapt to create best in class antibodies Invivyd received emergency use authorization (EUA) from the U.S FDA for a monoclonal antibody (mAb) in its pipeline of innovative antibody candidates Cautionary Note Regarding Forward Looking Statements   This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 Words such as “anticipates,” “believes,” “could,” “expects,” “estimates,” “intends,” “potential,” “predicts,” “projects,” and “future” or similar expressions (as well as other words or expressions referencing future events conditions or circumstances) are intended to identify forward-looking statements Forward-looking statements include statements concerning expectations related to the company’s future prospects including the company’s efforts to scale medical benefit from its core technologies and advance into more scalable higher value medicines that can protect Americans from COVID-19 and other diseases; the company’s research and development efforts; the role of Invivyd in the future of American medicine; the future of the COVID-19 landscape and the potential impact of COVID-19 on certain populations; the expectation that Invivyd’s mAb technology platform transcends the limits of vaccination to provide high-quality best-in-class medicines for vulnerable populations; the expectation to work with critical partners to rapidly deliver innovative mAb therapies to patients who need them the most; the company’s competitive position in the market; the anticipated contributions of the company’s directors; the company’s devotion to delivering protection from serious viral infectious diseases beginning with SARS-CoV-2; and other statements that are not historical fact The company may not actually achieve the plans intentions or expectations disclosed in the company’s forward-looking statements and you should not place undue reliance on the company’s forward-looking statements These forward-looking statements involve risks and uncertainties that could cause the company’s actual results to differ materially from the results described in or implied by the forward-looking statements progress and results of the company’s discovery preclinical and clinical development activities; the risk that results of nonclinical studies or clinical trials may not be predictive of future results and interim data are subject to further analysis; unexpected safety or efficacy data observed during preclinical studies or clinical trials; whether the company’s product candidates are able to demonstrate and sustain neutralizing activity against major SARS-CoV-2 variants particularly in the face of viral evolution; uncertainties related to the regulatory authorization or approval process and available development and regulatory pathways; changes in the regulatory environment; how long the EUA granted by the U.S FDA for a mAb in the company’s pipeline will remain in effect and whether the EUA is revised or revoked by the U.S FDA; the ability to maintain a continued acceptable safety Other factors that may cause the company’s actual results to differ materially from those expressed or implied in the forward-looking statements in this press release are described under the heading “Risk Factors” in the company’s Annual Report on Form 10-K for the year ended December 31 as filed with the Securities and Exchange Commission (SEC) and in the company’s other filings with the SEC and in its future reports to be filed with the SEC and available at www.sec.gov Forward-looking statements contained in this press release are made as of this date and Invivyd undertakes no duty to update such information whether as a result of new information This press release contains hyperlinks to information that is not deemed to be incorporated by reference in this press release Media Relations(781) 208-1747media@invivyd.com  Investor Relations(781) 208-1747investors@invivyd.com  Already have an account? Login This website is using a security service to protect itself from online attacks The action you just performed triggered the security solution There are several actions that could trigger this block including submitting a certain word or phrase You can email the site owner to let them know you were blocked Please include what you were doing when this page came up and the Cloudflare Ray ID found at the bottom of this page Listen to the latest episode of the “Detroit Evening Report” podcast A new study from the University of Michigan shows that Black stroke patients arrive at the hospital significantly later than their white counterparts Subscribe to the Detroit Evening Report on Apple Podcasts, Spotify, NPR.org or wherever you get your podcasts the research included data from more than 600,000 patients in the American Heart Association Get With The Guidelines Stroke Registry from mid-2015 through 2019 The study revealed that it took on average 28 minutes longer for Black patients with stroke symptoms to receive emergency care Researchers also found that EMS workers were roughly 20% less likely to notify emergency departments ahead of a Black patient’s arrival compared to a white patient The disparity was most prevalent in areas with a high poverty rate says getting a stroke patient to the hospital quickly is crucial for positive health outcomes “The therapies that we have for stroke are really effective but they are only available within a short time frame from the time that symptoms start,” Royan said Royan says there has been significant effort to making health care inside hospitals equitable and it’s time to bring those efforts outside the hospital as well “This is a disparity that must be addressed, as Black Americans have a higher prevalence of stroke, get strokes younger and die at greater numbers from the condition,” said Royan in a news release Do you have a community story we should tell Let us know in an email at detroiteveningreport@wdet.org WDET strives to make our journalism accessible to everyone. As a public media institution, we maintain our journalistic integrity through independent support from readers like you. If you value WDET as your source of news, music and conversation, please make a gift today Donate today » WDET is a community service of Wayne State University CONTACT Membership Sponsorship Studio Rentals Technical Support Pitch Us a Story Help/FAQ Other Inquiries Shows Podcasts Schedule Listen Live Contests & Giveaways SUPPORT WDET Membership Leadership Circle Car Donations Business Sponsorship Broadcast Partners Program More » INSIDE WDET About Staff Jobs & Internships Public File FCC Applications Invivyd ( (IVVD) ) has provided an announcement with his term expiring at the 2025 annual meeting of stockholders a venture capitalist with a focus on healthcare will receive compensation consistent with other non-employee directors and was granted an option to acquire 100,000 shares of common stock His appointment is expected to enhance Invivyd’s efforts to advance its monoclonal antibody technology platform which aims to provide high-quality medicines for vulnerable populations affected by COVID-19 and other diseases is a biopharmaceutical company focused on delivering protection from serious viral infectious diseases The company utilizes a proprietary integrated technology platform to develop best-in-class antibodies and received emergency use authorization from the U.S FDA for a monoclonal antibody in its pipeline See more insights into IVVD stock on TipRanks’ Stock Analysis page Disclaimer & DisclosureReport an Issue Invivyd ( (IVVD) ) has provided an announcement Disclaimer & DisclosureReport an Issue ONCE known as the 'Pearl of the Atlantic' a town in France has been compared to Brazil since being rebuilt Unfortunately, during World War Two this gave architects the chance to completely redesigned the town as only a few villas survived the town is full of white concrete low-rise buildings Only a select few of the original villas remained The more modern look meant that the former style of the town has disappeared but in its place, Brazilian-inspired concrete roofs appeared. Many of the villas built by architects after the war are now worth a fortune. One villa, located about five minutes from the beach but without sea views, recently went on the market for €1.1million (£942,199). In comparison, one of the remaining villas from the 1930, located only 600 metres from the beach But the emergence of the new villas in the 1950s were not greeted with open arms by local residents Charlotte explained that for a long time the villas did not have the same value in the eyes of the locals as the 1930s villas that has now changed and some of the 1950s are sold within days of being put on the market Rules in the area have been introduced to protect the villas, meaning that it is forbidden to put external insulation on walls and solar panels are only allowed if they cannot be seen from the road The rules also protect original doors and fittings may of which are unique having been made by artisans using wood "It is an effort but almost everyone agrees that it is worth trying to keep the vision alive of the people who rebuilt the town," Charlotte added Royan's history dates back to the 19th century Rich families from Bordeaux would take boast down the estuary and visitors from Cognac and Libourne would flock to the region A railway then arrived in 1875, allowing more visitors to travel to the town and build holiday villas. This result in holiday villas with grand towers - all in Gothic style One holiday village - Le Parc - stretched from the beach to the hill behind it and was full of ornate buildings Names like the Prince of Wales and Picasso stayed in the town and helped it to gain the nickname 'The Pearl of the Atlantic' When the German navy put huge guns and bunkers along the estuary mouth and buried mines across the town during World War Two, Royan completely changed Royan eventually ended up flattened by bombing raids and was one of the last towns to be liberated It wasn't until the 1950s when the town redeveloped Our journalists strive for accuracy but on occasion we make mistakes. For further details of our complaints policy and to make a complaint please click this link: thesun.co.uk/editorial-complaints/ a town of 18,000 inhabitants on the Atlantic coast south of La Rochelle was almost completely destroyed at the end of World War Two giving architects a blank canvas to rebuild it around the few seaside villas that survived low-rise town dominated by white concrete but with enough architectural follies from before and after the war to give interest Some of the villas command stratospheric prices situated at the mouth of the Gironde estuary had its heyday in the late 19th Century when it developed as a holiday resort Rich bourgeois families from Bordeaux were the first and it also attracted visitors from Cognac and Libourne families from Limoges and all over France built holiday villas in the town where The results were holiday villas with added towers (why not?) gothic flourishes or even Alpine fretwork and Japanese pavilions A holiday village called Le Parc extended from the beach and up the hill behind it The Prince of Wales and Picasso were some of the big names who stayed in the town which gained the nickname The Pearl of the Atlantic the good times for Royan ended in a big way during the war – the German navy put huge guns along the estuary mouth After D-Day and then the invasion by Allies of the south of France the local commander refused to quit and run back to Germany The result was that the town was flattened by bombing raids which included the first large-scale use of napalm by the US airforce and three days of heavy fighting in April 1945 just weeks before the official German surrender Royan was one of the very last towns in France to be liberated – Charles de Gaulle made it a political priority to have French soldiers chase Germans from the country only a few of the original villas in Le Parc remained the town was rebuilt with white concrete as the main material a history expert from the town hall’s heritage and culture section previously told The Connexion: “It was a deliberate choice to be low rise “The main architects and urban developers were influenced by Brazilian architecture which is why white concrete curves predominate instead of the grey used in places like Le Havre.” but the town’s municipality took the opportunity to rationalise access to the seaside such as a Brazilian-inspired concrete-roofed market It contrasted with the controversial dark grey concrete church of Notre-Dame de Royan which is hated and loved in equal measure in the town if owners wanted to build modern villas in contemporary styles to replace their old homes The villas built by architects after the war are now worth a fortune built on a rise five minutes from the beach four bedrooms and a pool in a 694m² garden Even an ‘ordinary’ 1930s villa without architectural flourishes Getting townsfolk to appreciate the 1950s buildings has been a long process “There was no problem with the pre-war villas but the 1950s ones for a long time did not have the same value in the eyes of the local population and the prices some of them fetch show that,” she said “Some are sold within days of being put on the market.” Urban development rules have been made to protect them – it is forbidden to put external insulation on walls and solar panels are tolerated only if they cannot be seen from the road Protecting features such as original doors and fittings is also a priority often the only solution is to build a second “It is an effort but almost everyone agrees that it is worth trying to keep the vision alive of the people who rebuilt the town.” Luxury treehouse, giant maze: Six unusual places to explore in France Downton Abbey’s new film puts French locations in the spotlight Why Strasbourg’s cathedral is one of France’s greatest treasures Learn about Cutting Patches and growing flowers to harvest solely for display Explore the rich history and artistic allure of this medieval hideaway Can you work out which idiomatic expression is depicted below FAD Magazine FAD Magazine covers contemporary art – News Exhibitions and Interviews reported on from London A new exhibition at the Museo Picasso Málaga will explore the radical development of Picasso’s artistic practice during the time he spent living in the French coastal town of Royan from 1939 to 1940 which will bring together Picasso’s sketchbooks from this period for the first time organised in collaboration with the Almine and Bernard Ruiz-Picasso Foundation will contextualise these notebooks by presenting them alongside other works Picasso created in Royan as well as documentation from that period photographs and Picasso’s poems will collectively illuminate this prolific chapter in the artist’s life and career Picasso produced eight sketchbooks filled with pencil and ink drawings while residing in Royan after relocating to the town with Dora Maar and his friend and secretary Jaime Sabartés following the outbreak of the Second World War Picasso’s mistress Marie-Thérèse Walter and their daughter Maya were already settled in Royan Picasso frequently used sketchbooks to capture visual ideas after moving to Royan and leaving behind two spacious studios in Paris the nature of his artistic activity changed Perhaps due to the limited availability of art materials in Royan – such as canvases and oils – Picasso purchased several ordinary notebooks from the local Hachette bookshop which allowed him to carry and use them wherever he went.  The drawings Picasso made in the eight sketchbooks reveal ideas not only for larger works A highlight of the exhibition will be the large oil-on-canvas Woman Dressing her Hair on loan from the Museum of Modern Art in New York The painting brings together many of the radical ideas and experiments around form and composition featured in the sketchbooks.  Picasso: The Royan Sketchbooks will bring to light Picasso’s methods of working and the ways in which he was affected by the Second World War providing an insight into a previously unexplored chapter in the artist’s life and career.  The exhibition is curated by Marilyn McCully and Michael Raeburn Picasso: The Royan Sketchbooks, 31st January – 30th April 2025, Museo Picasso Málaga Mark Westall is the Founder and Editor of FAD magazine - presented in partnership with the artist’s daughter Paloma Picasso Undiscovered painting by Picasso of a mystery woman hidden for more than a century beneath a painting from his famous Blue Period revealed Picasso: Printmaker – reached via a golden lift in the Living and Dying section – a fitting route to an exhibition chronicling the modern master’s life in works on paper Join the FAD newsletter and get the latest news and articles straight to your inbox 2025 is Final Deadline for Submitting Research Works to the Royan International Research Festival Royan International Research Festival which is a globally renowned event with a distinguished position in the scientific community once again calls upon leading biomedical researchers to take part in an intellectually stimulating and prestigious scientific competition this festival aims to expand the frontiers of knowledge and strengthen international collaborations it has become a prominent platform for showcasing and supporting exceptional scientific talent As we approach the 24th Royan International Research Festival we invite researchers and scholars to submit their valuable scientific papers through the website: www.royanaward.com Please note that the submission deadline is set for May 10 The closing ceremony will take place simultaneously with the Royan International Congress in September 2025 in Tehran Only works completed within the last three years and published in high-impact scientific journals will be eligible for review Submissions will be evaluated by a panel of distinguished national and international experts and the final awardees will be honored in a grand ceremony Selected researchers will receive not only a prestigious honor statuette and a $5,000 cash prize but also a rare opportunity to present their scientific findings at the Royan Twin International Congress—a platform designed for visibility and the expansion of new horizons in science If you are looking for an opportunity to make a global impact in the world of research the largest biomedical festival in the Middle East is truly the gateway to a bright and scientifically promising future The Cameroonian has continued to make mistakes both in the Premier League as well as in Europe which have cost the Red Devils big time And the Portuguese is on the lookout for a new No. 1, especially given Altay Bayindir’s uncertain future while the current No 1 has also been linked with a move away Senne Lammens is one name who has been frequently linked with a move to Old Trafford recently with the Belgian ace impressing for Royal Antwerp The “exciting” shot-stopper has kept seven clean sheets in 33 games and has earned praise for pulling off brilliant close-range saves And his displays have alerted several Premier League sides to his availability with both Manchester clubs joining the likes of Newcastle West Ham and Wolves in the chase for the 22-year-old Not only in England but also European giants such as Bayern Munich and Paris Saint-Germain are also looking at the 6ft 3in goalie CaughtOffside have claimed Pep Guardiola is on the lookout for an able replacement for Ederson which means a potential showdown between the City boss and Amorim is on the cards The 20-time English league champions have the upper hand in that case with the player himself recently revealing that he would find it tough to turn down a move to the Theatre of Dreams “Premier League giants Manchester City and Manchester United are looking to sign a new goalkeeper in the summer transfer window Both are looking to make moves for a new player in goal and they are fighting for the same goalkeeper “The uncertain future of Man City goalkeeper Ederson is forcing Pep Guardiola to enter the market to sign a new goalkeeper while Ruben Amorim has been unimpressed with the performances of Andre Onana this season “According to Caught Offside sources Royal Antwerp’s 22-year-old Belgian goalkeeper Senne Lammens is attracting the attention of the giant clubs of Europe and the Premier League with his performance this season.” The report claims Antwerp are looking at earning €20-€25 million from his sale and whether INEOS give the green light to proceed will be interesting to see United are not in the pink of health financially and the Red Devils will have to prioritise which positions to strengthen first before proceeding midfielder and wingback much more urgently finances will dictate in which direction United proceed in during the transfer window Feature image Octavio Passos via Getty Images including the 25th Congress on Reproductive Biomedicine and the 20th Congress on Stem Cell Biology and Technology kicked off today at Shahid Beheshti University The event will also include the 19th Seminar on Nursery and Midwifery the Royan International Congress mainly aims to boost the links between researchers and practitioners from all over the world despite the extant challenges It will cover main topics through highly scientific & extremely innovative online sessions The congress revolves around various fields including genetics of infertility infection and antiretroviral therapy (ART) A total of 33 international scientists and researchers from the U.S. Qatar and India are scheduled to present lectures The event will also include four lectures and 169 articles in the form of poster presentations on topics like stem cell engineering will officially receive the 6th Kazemi Prize - a major scientific award in recognition of the late Saeid Kazemi Ashtiani’s efforts in the field of stem cells Royan Institute was established in 1991 by the late Dr Saeid Kazemi Ashtiani and a group of researchers and physicians in the Iran University of Medical Sciences of Academic Center for Education and Research (ACECR) as an outpatient surgery center to provide medical services to infertile couples as well as research and training in reproductive sciences Reproductive Biomedicine and Stem Cells Biology and Technology has been demonstrated to be one of the most successful experiences of scientific gathering in Iran and West Asia since 2000 the research fields at Royan Institute also extended into stem cell studies the research findings were adjusted for application in regenerative medicine and cell therapy approaches Royan Institute focuses on increasing the success rate of infertility treatment alongside embryo health and the level of public health through cell therapy clinical services During these twenty years of active involvement in sharing and exchanging scientific knowledge and expertise with renowned scientific institutes and scientists the Royan Congress has helped to form many shared scientific projects and exchanges Royan Architecture Month 2024 launches in the French city where many travel to see midcentury builds by the sea from Notre Dame church to Palais des Congrès including the Notre Dame church and the Palais des Congrès as well as current restoration projects in the midcentury realm and the creation of the Municipal Technical Centre A key addition to this year’s festival is the offering of guided tours of the Palais des Congrès the son of the original architect and father of modernist Royan perforated façade remains intact with Jean Prouvé-designed panels in Vermeer grey and yellow and magnificent play of volumes assembled in light' 'We are working with the mayor and banding with other mid-sized European coastal cities with modernist collections to raise awareness and protect our buildings,' said Royan deputy mayor Nadine David Such preservation efforts and focused attention also work towards healing a collective wound: bombs destroyed 85 per cent of Royan in the Second World War Bordeaux-based architect Claude Ferret led the charge to turn the city into a seaside resort with white concrete Oscar Niemeyer’s Pampulha resort particularly inspired him Ferret’s work marked the start of Royan’s renaissance as a modernist coastal gem escapism and design stories from around the world direct to your inbox royan.fr Stacy Suaya is a Los Angeles-based writer focusing on design Her stories have appeared in New York Times Styles one being aimed at the entry-level buyer and/or park fleet buyers The new Swift Royan range offers excellent value and still has some design flair The 35ft x 12ft two bedroomed model should prove to be popular out of the three on offer The exterior is simple in design with no front doors or even a bay window but it does have all the drains and guttering in place and the Swift Royan uses a galvanised chassis as well as Swift’s bonded construction system for extra warmth It might not be a head turner – but it’s only the front flat windows that give you a clue this isn’t a high- end holiday caravan On entering the Swift Royan static caravan it feels pleasant and modern and first impressions are not of an entry level unit especially the front lounge area with its comfortable L-shaped built in settee There’s a low table for your morning coffee or tea and a large side TV cabinet with a deep drawer and shelving LED ceiling lights provide the illumination and modern light curtains brighten the décor The dinette is by the entrance door and consists of a movable bench seat on one side and two circular cushioned stools – though four dining chairs can be ordered as an option There’s a large side window to look out while you have your meal while opposite is the L-shaped kitchen which provides some useful worktop space There are several handless cupboards and wall units too so storage is good – some with open shelving With a white colour scheme mixed with a traditional wood grain it all looks very modern and tasteful The oven has a four burner spark ignition hob complete with extractor fan No fridge or microwave are fitted as standard but provisions are made for these to be added The side twin bedroom is designed for children Here there’s an overhead shelf above beds and a small wardrobe offers reasonable hanging space Across the corridor the main bathroom has a good-sized sliding door shower cubicle toilet and pedestal sink with a mirror above Stepping into the master bedroom and we found it was quite spacious The king size bed has overhead shelving above plus hanging open bedside cabinets at either side in a light woodgrain There’s also a large built-in wardrobe and a small vanity unit with a mirror Next to the large wardrobe is a simple en-suite with a loo and hand basin – but no shower Verdict:  The Swift Royan holiday caravan is for the first time buyer Although there are a few tell tale signs it’s at the lower end of the market They have kept price affordable and the Royan isn’t a static caravan that lacks in too much The interior is simple but modern and tasteful and the options list allows extras that are important to the buyer so they can add to the enjoyment of the Royan plenty of bedroom storage and pleasing colour scheme Minus points: No storage in the main bathroom and limited cupboard space and shelving in the lounge In a nutshell: An entry-level holiday caravan with good essential specification  including a galvanised chassis and central heating Other Swift Royan models available: 28ft x 12ft two bedroomed Others to look at: ABI Coworth 36ft x 12ft two bedroomed Arronbrook Topaz 35ft x 12ft two bedroomed Key optional extras: Exterior colours and finish Spotted in the classifieds: A 2025 Swift Royan static caravan for sale in Caernarfon Cost to insure this sited holiday caravan would be £247** For more information about the range of holiday caravans and lodges from Swift visit www.swiftholidayhomes.co.uk or call 01482 847332 *Extra charges will be made by park operators and/or distributors for transport and siting and annual maintenance Please check the price carefully before you commit to buy as prices vary considerably dependant amongst other factors on the geographical location of your chosen park **Leisuredays static caravan insurance quote based on 2025 Swift Royan two-bedroomed holiday caravan insured for £53,500 (£48,500 for structure and £5,000 contents) Owners are a 68-year-old retired couple with previous static caravan insurance and three years no claim discount Premium includes insurance premium tax at the current rate and is correct as of 27/02/2025 and website in this browser for the next time I comment Δdocument.getElementById( "ak_js_1" ).setAttribute( "value" The Arts and Humanities Research Council (AHRC) has announced that the University of Nottingham along with six other higher education institutions (HEIs) in the Midlands which reflect the HEIs’ successes in Arts and Humanities research and research supervision are for scholarships for arts and humanities doctoral study DeMontfort University and Coventry University have all secured Doctoral Landscape Awards enabling these leading Midlands institutions to continue to build on the thriving relationship and collaborative community of doctoral students producing world-class arts and humanities research Only 50 universities across the UK have received the funding which has been allocated through a formula-based approach Each institutional award will support 15 full-time PhD students with studentships starting in October 2026 – three per year over a five-year period – and will contribute towards the AHRC’s three-fold strategy for post-graduate research funding alongside Collaborative Doctoral Partnerships and Doctoral Focal Awards All institutions receiving Doctoral Landscape Awards will be part of an AHRC-supported regional Hub; preparations to set up a Midlands Hub are currently co-ordinated by Professor Nicola Royan and the University of Nottingham Professor Royan, who is also Director of Midlands4Cities said: “I am delighted to be leading the discussions on the Midlands Hub with a view to maintaining the strengths of Midlands3Cities and Midlands4Cities developing collaborations and being a point of contact for external partners.” AHRC Executive Chair Professor Christopher Smith said: “The AHRC Doctoral Landscape Awards provide flexible funding to allow universities to build on existing excellence in research and opportunities for innovation across the arts and humanities They will support the development of talented people and diverse and internationally-attractive research and innovation system.” More information is available from Professor Nicola Royan in the University of Nottingham’s School of English, via nicola.royan@nottingham.ac.uk Ranked 24 in Europe and 15th in the UK by the QS World University Rankings: Europe 2024 the University of Nottingham is a founding member of Russell Group of research-intensive universities Studying at the University of Nottingham is a life-changing experience and we pride ourselves on unlocking the potential of our students expressed in the vision of our founder Sir Jesse Boot which has seen us lead the way in establishing campuses in China and Malaysia - part of a globally connected network of education Nottingham was crowned Sports University of the Year by The Times and Sunday Times Good University Guide 2024 – the third time it has been given the honour since 2018 – and by the Daily Mail University Guide 2024 The university is a major employer and industry partner - locally and globally - and our graduates are the third most targeted by the UK's top employers according to The Graduate Market in 2024 report by High Fliers Research We lead the Universities for Nottingham initiative in partnership with Nottingham Trent University a pioneering collaboration between the city’s two world-class institutions to improve levels of prosperity health and wellbeing for residents in the city and region we are proud to call home More news… Connect with the University of Nottingham through social media and our blogs , Six new inductees to the Saskatchewan Agricultural Hall of Fame were announced at the 2025 Crop Production Show in Saskatoon today Among this year’s inductees is Bob Bors former head of the Fruit Program in the Plant Sciences Department at the University of Saskatchewan To say that Bors was thrilled to learn he was being inducted into the Saskatchewan Agricultural Hall of Fame would be quite an understatement Grain and oilseed millers are predicted to see sales volumes and margins decline in 2025 according to Farm Credit Canada’s food and beverage report “I practically cried when I heard the news,” Bors said following his introduction to the crowd gathered at the 2025 Crop Production Show “That they wanted to recognize me is something else.” Bors’ work on haskap berries – the number one variety in the world he quickly adds was named after his daughter Aurora – has literally borne fruit around the globe “I never thought anything done in Saskatchewan could become world famous,” said Bors “But we’re world famous for our haskap Bors was joined on stage today by three other inductees while two more received the recognition posthumously were both recognized for their work with their family-namesake “Getting into business our goal was never to seek awards,” said Gerry “But it’s very much appreciated said the award reflects positively on the people who work in their family’s business “It acknowledges the hard work of the people from that area and what you can do from rural Saskatchewan.” another of this year’s inductees in attendance started his career as a radio reporter in Weyburn which is where he began to specialize in agriculture Wilson went on the create the well-known Prairie Farm Report television show a graduate of the University of Saskatchewan’s Western College of Veterinary Medicine operated the Sherwood Animal Clinic in Regina the main large-animal vet clinic in the area for more than 20 years Harold Martens was a rancher who also served as a member of the legislative assembly a senior official with the provincial Ministry of Agriculture and was a board member of several livestock and farming associations Martens also served as president of the Saskatchewan Stock Growers Association from 2011 to 2014 and was board chair of Livestock Services of Saskatchewan from 2014 to 2022 “This award recognizes the lifetime of commitment innovation and plain hard work to help strengthen and grow Saskatchewan’s agricultural sector,” said Ag Hall of Fame president Reed Andrew in introducing the inductees “Congratulations to this year’s inductees they have made a lasting impact on agriculture and the province as a whole.” A formal ceremony celebrating the inductees will be held April 26 Check out all our 2025 Western Canadian Crop Production Show coverage here Newsletter Sign Up - Receive free Western Producer newsletters Breaking ag news stories and commodities markets 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It ended up as a major distraction.What really mattersIn a world with too much noise and too little context We don’t flood you with panic-inducing headlines or race to be first We focus on being useful to you — breaking down the news in ways that inform We rely on readers like you to fund our journalism Will you support our work and become a Vox Member today and other people close to the matter describe an investment firm in disarray by Theodore Schleifer Link Stephanie Keith/Getty ImagesSeven years ago, a smooth-talking associate of Peter Thiel promised that he had launched the “capstone” to Thiel’s investment empire naming their new firm after a mythical metal in Lord of the Rings because it was flashy yet permanent “It’s invaluable,” leader Ajay Royan told one interviewer about Mithril Capital It has all of the things we’d like to be associated with.” But Mithril Capital is primarily associated with some other things these days: drama and unanswered questions about its finances Mithril had its best moment yet last week when a portfolio company, Auris Health, sold to Johnson & Johnson for more than $3 billion — returning at least $500 million to the fund The late-stage investment firm has been a slow-burning mess for the past several months The firm’s troubles have disappointed Silicon Valley’s highest-profile investor according to multiple people close to Thiel who has lent his brand name to the firm but is not operationally involved And it has left a long list of scorned parties slowly shrinking the firm’s headcount of investors — despite having more than $1.3 billion in assets under management That has all raised questions about what exactly is happening with the money and how Royan is handling it and other people close to the matter who spoke with Recode Mithril declined multiple requests to make Royan available for an interview for this story The firm also declined to comment on the record to address any specific pieces of reporting “Mithril has invested deliberately and differently We owe the success of this patient approach to entrepreneurs who work for the long term amid a trend-ridden industry,” a Mithril spokesperson said This is a classic Silicon Valley story of big celebrities and what can happen when you pair big money with little accountability But it is not a five-alarm fire in the orbit of Thiel who is proudly “contrarian” and no stranger to drama Despite raising $740 million for its second fund — with a first close in April 2016 — Mithril Capital has invested only about $90 million of the cash according to multiple people with knowledge of the figures That’s highly unusual for a firm at this point in its investment period; a typical firm would probably be spending at a three- or four-times faster clip Royan has long been clear that he wants to be able to wait out high valuations that have dominated tech investing over the past decade — crafting a 12-year fund instead of the usual 10-year fund to give him more flexibility Royan graduated from Yale at age 20 and got to know Thiel while he was becoming a minor celebrity at PayPal The two have now worked together for 16 years Mithril has always been a somewhat unusual firm with an emphasis on investing outside of Silicon Valley in places like Kansas City and with a single clear leader “Mithril is a unique fund: By design its orthogonal approach is not for everybody and it’s been uniquely successful,” said Jeremiah Hall “As the largest LP in Mithril and the chairman of its investment committee Peter is proud of Ajay’s leadership.” Troubling to some are concerns about Mithril’s management fees which an investment firm uses to pay for operational costs like salaries Royan has told people that he and his entities control 100 percent of the management company meaning that he would be entitled to 100 percent of the fees and would decide where they go The source with knowledge of Mithril’s thinking disputed the ownership structure of the management committee but declined to provide any details Paperwork filed with the SEC shows that more than 75 percent of the management company is owned by a limited company in the Cayman Islands called Talleus which in turn is owned 75 percent or more by Royan The firm is likely collecting as much as $20 million a year in management fees We don’t know exactly how much the firm spends but people close to Mithril say they can’t imagine that the firm is spending more than half of that on operational expenses The source with knowledge of Mithril’s thinking disputed the $20 million figure but also declined to provide an alternative Perhaps the only other person with that data? Royan’s sister, Anuja Royan, who he hired as the firm’s chief financial officer — she has a separate staff that is technically part of an affiliate based in Canada called Mithril360 While she is well credentialed as a former public company CFO her role has troubled some former employees and others close to the firm and raised questions about its internal transparency and governance “A lot of things that were really transparent suddenly became not transparent at all,” said one former employee Ajay Royan told Bloomberg in 2017 that Mithril does not “charge excessive fees.” But he was not exactly known for being thrifty with management money Former employees describe Friday catered lunches where costs could run over $100 per person and Royan was known internally for a “book ordering problem” — a former employee said that “unbelievable amounts of books” would be delivered each week to the office by Amazon to maintain the firm’s extensive library “What made [Silicon Valley] really attractive was it was one giant incubator as a society, with a lot of pay-it-forward culture and a low cost of trying,” he told TechCrunch last year “Now I’m worried about all three of those.” That decision has been unpopular internally Some employees have been resisting moving to Austin and leaving the heart of the tech ecosystem four junior employees in San Francisco — some of whom are the children of limited partners in the fund — believed that they were soon to be terminated because they would not move to Austin according to former Mithril employees in touch with current employees Then at the last second — as Recode was making inquiries about this story — the employees were spared But the rest have been operating in some fear of looming axings and are now without an office The source with knowledge of Mithril’s thinking confirmed that the firm did ask all its employees to move to Austin but insisted that it was open to its employees working remotely This has all led to a work environment that alternates between absent and intimidating and where Royan has a reputation for being a difficult boss at least 11 members of the investing team have left the firm since the firm’s founding in 2012; five departed after the second fund had its first close in the spring of 2016 That turnover has forced at least some founders to have to cycle through multiple different people from Mithril on their board While those 11 are of different seniority levels a common concern for multiple people across the organization has been the salaries that Mithril has paid to its investors which multiple sources described as below-market In a work hierarchy described as very top-down, some sources describe Royan, who now splits his time among Austin, San Francisco, and Canada, as hard to get ahold of and say communication is an issue. That can be true for Mithril’s limited partners, even the venture firm’s own investors. Those relationships are tightly controlled by Royan, who is the firm’s sole managing general partner and who in general likes to avoid confrontation Limited partners have included the Singaporean sovereign wealth fund Temasek and a heavy mix of personal offices that manage family money from overseas Money has come from the billionaire empires of Egypt’s Sawiris family and Malaysia’s Krishnan family some limited partners still speak highly of Royan and are sympathetic to his argument about being slow and steady with deals at a time of high valuations in Silicon Valley should quiet some concerns about his strategy But other limited partners have been trying to survey their options Some limited partners have tried confronting Royan over his spending rate And it’s especially hard for limited partners to organize themselves since Mithril unusually does not have a regular annual meeting — during which limited partners typically trade contacts The firm may be listening to the calls for change — last week, it posted a job listing for a chief accounting officer in Austin to handle financials and deal with limited partners A first fund is raised on reputation — in this case perhaps seeing it as a way to get into Thiel’s choosier flocked to Mithril Capital in 2012 given its $100 million blessing from Thiel And its first fund has performed quite well with investments in not just Auris but also Thiel’s data analytics company Palantir Thiel doubled his personal investment in the second fund But that’s when the spigot got clogged Royan appeared no longer interested in deals “[W]rite clichés on a roulette board and just roll the wheel,” said one former employee “He literally did not want to compete If there was a process or bidding war or something resembling a competition he would just walk,” the employee said ‘I don’t want to outbid.’” The source with knowledge of Mithril’s thinking said the pace of spending in the second fund was about equivalent to the pace in the first fund Now, a further challenge is that the team simply may be too small to compete, with only a few professional investors who can lead their own deals remaining. The source with knowledge of Mithril’s thinking said it employs 17 people, but that figure includes many people who work for Mithril360 and in support functions. Only eight employees are listed on the firm’s website who has paid relatively little attention to the drama at Mithril in recent years But as Recode began inquiring about the state of his late-stage venture arm Thiel in recent weeks has become increasingly agitated with Royan and the state of affairs there who is technically the chair of Mithril’s investment committee has worked with Royan for going on two decades dating back to their work at Clarium Capital and associates of his say they have been reluctant to bring up the situation at Mithril with him he is described by associates to be frustrated Thiel gave his imprimatur to Royan’s fund in the first place But Thiel’s focus is less on Silicon Valley investments and more on other pursuits. He’s active in politics. He has made noise — but with little evident follow-through so far — about building a conservative media company And he sold his San Francisco mansion and moved to Los Angeles (although Recode has learned that he recently bought a previously unreported house in Palo Alto) motivated by a revulsion to Silicon Valley’s politics and culture Mithril has given up its modern industrial office in San Francisco’s Presidio But despite announcing plans to move to Austin five months ago, Mithril Capital’s office — overlooking the Texas Capitol — today remains sparsely furnished. This article originally appeared on Recode.net. Understand the world with a daily explainer plus the most compelling stories of the day, compiled by news editor Sean Collins. Sorry, a robot is probably a safer driver than most humans. OpenAI released a model that tells users they’re right — no matter what. That’s more dangerous than it seems. How the company’s transition to for-profit will affect everyone. Computing has a big energy appetite. What does that mean for our climate goals? America’s EV charging network is stronger than ever. Mithril Capital raised over $1 billion on the name of Thiel one of Silicon Valley’s biggest celebrities Now federal investigators are looking under the hood LinkJohn Lamparski/Getty ImagesFederal investigators are probing the conduct and practices of Mithril Capital a venture capital firm co-founded by Peter Thiel US officials — including the FBI — have in recent months questioned some people close to Mithril regarding concerns of possible financial misconduct at the firm according to people familiar with the matter who insisted on anonymity given its sensitivity Mithril confirmed in a statement that its lawyers are in touch with government authorities has worked with Thiel for almost two decades and has used that relationship to raise over $1 billion Royan has frustrated some of his investors by sitting on some of their money rather than investing it in startups — while almost certainly raking in millions of dollars in fees for himself This federal probe is just the latest — but most significant — problem for the firm which has increasingly struggled with internal tensions and Mithril could eventually be cleared of wrongdoing If you have more information about the situation at Mithril Capital or at other venture capital firms please contact me at teddy.schleifer@recode.net or at 202-809-2946 on messaging services such as Signal When asked if Mithril and Royan were cooperating with the government probe a Mithril spokesperson said: “This is a foiled plot by a self-serving ex-employee There are no allegations from any government agency our attorneys are in contact with government authorities in order to protect [investors] and portfolio companies against any extortionate behavior.” The drama around Mithril pulls back the curtain on a venture capital industry that is awash in money but governed by relatively few rules And it raises questions about how often similar situations are unfolding quietly in high finance but don’t manage to draw the scrutiny of the federal government And while the probe is in the early stages it threatens to destabilize the world of Thiel who heads an enormously influential network of tech investors and political allies across Silicon Valley Thiel sits on the board of Facebook; he’s also built an unusual amount of political power and raised his public profile as one of Silicon Valley’s most prominent supporters of President Donald Trump A federal investigation could subject Thiel, who has not publicly distanced himself from Royan, to new scrutiny as investigators put the firm he co-founded under a microscope. It could also stain the reputation Thiel has established for having a Midas touch in investing A spokesperson for Thiel, Jeremiah Hall, declined to comment on the new probe, but has said previously that Thiel was “proud” of Royan In the months since Recode reported on unanswered financial questions at Mithril according to people familiar with the matter The firm has lost staff and has adopted a more defensive posture Two of the other managing directors at Mithril recently left the venture capital firm in contentious exits the people say — departures that until now haven’t previously been reported which are at least the sixth and seventh people to leave the investing team since the spring of 2016 have essentially stripped a shop with more than $1.2 billion in assets down to a bare-bones operation whose remaining senior full-time employees consist of Royan That shrinking staff list might explain why the firm also removed the “Team” page from its website about two months ago Its entire website now features just a single substantive paragraph of information about the firm Royan is described by sources close to Mithril as obsessed with trying to plug up leaks in his network tactics that these sources say have further sapped morale Royan called his staff to the offices of a downtown San Francisco law firm for a heated intimidating meeting where he implored them to feel gratitude for working at Mithril he repossessed some of his staff’s phones and computers to try to find leakers a search mission that effectively cut off some of his remaining employees from any real Mithril work (Mithril told Recode “this was a device upgrade to increase productivity.”) And in recent months Royan offered at least one former employee some additional financial upside in Mithril funds — if that employee agreed to become a consultant for the firm and signed reinforced nondisclosure agreements is not the only entity scrutinizing Mithril for possible financial misconduct One of the most powerful investment advisers in Silicon Valley is looking into Mithril over financial mismanagement according to people briefed on Cambridge Associates’ activity The firm’s clients have invested millions into Mithril’s second fund which recommended that they invest in Mithril in the first place Cambridge Associates is an outside investment adviser to wealthy families and foundations serving as a powerful gatekeeper of sorts between Silicon Valley and the richest people in the world While it cannot compel cooperation in the same way the federal government can Cambridge Associates is a behind-the-scenes powerbroker in tech investing and its scrutiny could pose reputational risk to Mithril Capital and Thiel’s empire more broadly Cambridge Associates officials repeatedly declined to comment Mithril denies that Cambridge Associates is investigating its firm All of this months-long drama surrounding Mithril has proven to be an embarrassing series of events for Thiel, who has personally given a total of $300 million to the firm and is tied to Mithril by reputation Some entrepreneurs and investors have chosen to work with Royan specifically because they thought it could give them greater access to Thiel even though he is not involved in Mithril’s day-to-day operations While Thiel has a high appetite, in general, for media spectacle, part of the reason Mithril’s drama is so notable is because Thiel projects typically are well-run. Royan promised when he started the firm that it would be the “capstone” to Thiel’s investment empire Mithril said that many of its LPs “have expressed overwhelming appreciation for Mithril’s disciplined deployment of capital and exceptional returns in this late-cycle environment.” Other prominent investments by Mithril include the Thiel-founded data analytics company Palantir, and, according to sources, uBiome, a biotech company under its own federal investigation that just last week filed for bankruptcy that is a highly unusual pace of deployment for a venture capital firm which charges its investors management fees in order to invest money into startups on their behalf Royan suddenly sent investors a long investor update that defended his strategy — a move read by at least some investors as an attempt to quell their concerns he’s also begun quickly trying to spend the money: He told investors that he would be spending about $90 million on upcoming deals a sum that includes Neocis and Glance; if actualized that would mean Mithril has invested about $180 million of the total $740 million that it collected Mithril told Recode that it has communicated its investment strategy to its investors and that the firm “takes a disciplined and concentrated investment approach.” But over the course of the eight-page investor letter Royan said not a word about any of the turnover or drama at his firm in the past year which in the words of one person familiar with the matter was “glaring in its omission.” Those management fees go further in a low-tax state like Texas, where Mithril Capital said it was moving late last year. Several employees resisted the sudden move to Austin, which has a much smaller startup scene than Silicon Valley. Royan has said the move was rooted in his distaste for the Bay Area two sources told Recode that Mithril leaders alluded to tax advantages when privately explaining the multiple reasons for the move And Department of Justice officials in San Francisco have increasingly expressed interest in regulating the world of Silicon Valley investors and possible fraud with the US Attorney’s Office’s new Corporate Fraud Strike Force. The FBI, the investigative arm for the DOJ is one of the agencies involved in the Mithril probe Royan can proceed with his work even as federal investigators probe his firm Royan has added to his public relations team That appearance, though, might be contingent on how the federal probe plays out. we are considered among the leading countries in stem cell science in the region and so far we have been able to produce several products that are going through the stages of clinical trials and obtaining their license; It is expected that these products will be supplied to the pharmaceutical in the next two years,” Leyla Taqiyar Noting that the skin products are tissues of specific skin cells like fibroblast and keratinocyte “They are produced in specific dimensions and in the form of sheets and can be used to treat burns and diabetic foot ulcers.” “We have also made products by using stem cells to treat rheumatoid arthritis and chronic back pain and these products have now completed their clinical trial phase and are in the process of obtaining a license,” Taqiyar said Iranian researchers at Royan Research Institute had also made new discoveries by studying the role of secretions (exosomes) isolated from stem cells in repairing the cartilage of the amputated finger “This research project aims to investigate the effect of secretions (exosome) isolated from stem cells on repairing the cartilage of an amputated finger researchers have conducted studies on the amputated finger of a mouse,” Taqiyar told ANA at the time “Exosomes are cell secretions that can be changed by manipulations performed on them in research processes Human and animal body cells have the ability to release other secretions with the genetic manipulations,” she added “Secretions caused by mesenchymal stem cells with the manipulations carried out on their genome enjoy the capability to repair the damaged tissue and organ of the body,” Taqiyar said “The main goal of this research was to investigate the secretions released from the mesenchymal stem cells of the mouse’s amputated finger the initial phase of this research is testing on animals the necessary clinical tests will also be performed on the human body,” she noted Issues with signing in? Click here Need help signing in? GPI was founded in 2016 by managing partners Khai Ha all ex-members of Ontario Teachers’ high-conviction equities group Your email address is already registered with us. Click here to receive a verification link and login. Don't have an account? Click here to register Please check your spam or junk folder just in case The private company that runs Parc Prison has denied covering up the 25th death related to the jail in Bridgend since the beginning of 2023 G4S was responding to an allegation made by Zack Griffiths who runs a Facebook platform called HMP Prisons Justice Group Mr Griffiths issued a statement that said: “On June 5 we reported that something was happening in HMP Parc We received some information from a source the details we felt were somewhat vague and uncertain with sadness I can confirm that there was a ‘secret death’ that was never made public “Mr Henry Royan died at HMP Parc on June 5 bringing the total deaths to 25 [since January 2023] “We were aware on the day of some issue at the prison I am shocked that HMP Parc never released this information.” Mr Griffiths went on to point out that the death occurred during the first week that new Parc director Will Styles was in charge who formerly ran G4S’s HMP Five Wells in Northamptonshire took over from previous director Heather Whitehead Ms Whitehead’s departure with immediate effect was “not in response to one single incident” Ten inmates had died at the prison since February 27 2023 and three prisoners were also taken to hospital following disorder at the prison days before Ms Whitehead was replaced A spokesperson for HMP Parc emphatically denied that there had been a cover-up in relation to Mr Royan’s death A HMP Parc spokesperson said: “Mr Robert Royan (date of birth 17.01.1953) passed away on Wednesday 05 June 2024 His next of kin have been informed and our thoughts are with his family and friends this will be investigated by the Prisons and Probation Ombudsman and the cause of death is for the coroner to determine.” had been a hospital inpatient since April 29 It is not thought that his death was drugs-related When he was jailed at Swansea Crown Court in 2018 for setting fire to an electricity meter cupboard at the flats he lived in at Pembroke Dock he was said by the sentencing judge to have had a lifelong obsession with causing fires At least four of the deaths since February 2023 are believed to be drug-related while one prison staff member has been arrested in connection with drug dealing there South Wales Police said in March that a Nitazene – a synthetic opioid drug – had been identified in connection with all four deaths had been identified in two of the four deaths G4S has previously said it has a “zero-tolerance policy towards drugs” Two former inmates at Parc have spoken recently to NationCymru about a culture in which prison officers bring drugs into the jail in return for payment told us: “Our Facebook group gets a lot of information from former and current prisoners I’m aware of one officer at Parc who has been bringing in drugs for prisoners since at least 2014 So far as I’m aware he’s still doing it now “Recently a Parc prison officer contacted the group to tell us he was aware of a colleague who was bringing in drugs but didn’t want to identify them because they had a family to support and he didn’t want them to lose their job but the spotlight is on Parc because of the number of deaths.” G4S has acknowledged there is a problem with drugs getting into the prison and has previously stated: “Allegations of any wrongdoing by a member of staff are thoroughly investigated and reported to the police where appropriate.” Δdocument.getElementById( "ak_js_2" ).setAttribute( "value" The Texans would take their stetsons off to HMP Parc… Connect with Nation.Cymru on Facebook and Twitter If you would like to donate to help keep Nation.Cymru running then you just need to click on the box below it will open a pop up window that will allow you to pay using your credit / debit card or paypal Enter your email address to receive instant notifications of new articles All information provided to Nation.Cymru will be handled sensitively and within the boundaries of the Data Protection Act 2018 In 2017 Nation.Cymru was launched after raising £5000 from a crowdfunding campaign Today it is one of the fastest growing news sites in the UK attracting over 1.5 million visitors a month We are not backed by billionaire owners or hidden behind a paywall but we depend on our readers' support to continue our work If everyone who visited the site over the course of a month donated at least £1 we would have enough funding for the next eight years To guarantee our future please consider making a donation today. Radisson Individuals expands to Turkey with its first property nestled in historic Istanbul Radisson Hotel Group is delighted to announce the opening of Royan Hotel Hagia Sophia Istanbul the first Radisson Individuals hotel in Turkey The hotel is located in the heart of the historic peninsula within walking distance of many attractions The opening of Royan Hotel Hagia Sophia Istanbul a member of Radisson Individuals introduces a fifth Radisson Hotel Group brand to Turkey and brings the Group’s portfolio across the country to over 40 hotels in operation and under development features 49 standard and superior rooms and suites equipped with a wide range of amenities such as in-room coffee and tea facilities and free high-speed Wi-Fi to make guests feel at home with bespoke personal touches Guests can enjoy rooms with views onto the gardens or onto the stunning Marmara Sea the Lobby Lounge which serves lunch and dinner in a warm and relaxing atmosphere and the Rooftop Restaurant which offers breakfast and a sumptuous international culinary experience Africa & Turkey at Radisson Hotel Group says: “We are delighted to announce Radisson Hotel Group’s further expansion in Turkey with the signing and opening of our first Radisson Individuals hotel in the country Our newest brand is aimed at individual hotels with strong service scores and existing hotel identities that wish to remain independent or may be considering over time transitioning to one of the Group’s core brands The hotel will benefit from Radisson Hotel Group’s global network and capitalize on the Group’s strong presence in the country where we aim to reach over 50 hotels in operation and under development by 2023 but also to further cement our leadership in Istanbul We thank our partners for their trust and support.” a member of Radisson Individuals is located in the prime area of Sultanahmet where guests can immediately immerse themselves in Istanbul’s rich history Minutes from the old historic city center and key historic sights from three empires Sultanahmet is a top destination offering a wide variety of restaurants cafes and hotels which can be easily explored on foot or by tram Turkey has witnessed a constant growth and remains one of the most popular countries for tourism We are proud to welcome the first Radisson Individuals in Turkey which further diversifies our brand offerings across the market but also demonstrates the recognition of Radisson Hotel Group with an already established presence across Istanbul our guests will benefit from a new exclusive offering in the center of the old town." General Manager of Royan Hotel Hagia Sophia Istanbul a member of Radisson Individuals comments: "It is a great pleasure to announce this exciting project in collaboration with Radisson Hotel Group as we open the first Radisson Individuals in Turkey Radisson Hotel Group has demonstrated a pragmatic approach to support the integration of our hotel into their network in a rapid time and we are looking forward to further expanding our partnership in the future while leveraging the Radisson name distinct architectural and historical design we are confident that the Royal Hotel Hagia Sophia Istanbul a member of Radisson Individuals will be a great success." In response to the need for independent hotel owners to gain further brand exposure and consumer confidence Radisson Hotel Group launched last year the Radisson Individuals brand - a new conversion brand that offers independent hotels and local regional chains the opportunity to be part of the global Radisson Hotel Group platform benefit from the Group’s international awareness and experience whilst maintaining their own uniqueness and identity Joining Radisson Individuals is an ideal first step for individual hotels with strong service scores who wish to remain independent or may be considering transitioning to one of the Group’s successful core brands as well as offering a strong proposition for local hotel brands seeking to explore additional distribution channels and/or co-branding options and are designed to ensure guest safety and peace of mind from check-in to check-out Read more about the hotel here YEŞİM DOĞUKAN, District Marketing & Communications Manager, Turkey, Ukraine, Georgia, Azerbaijan, Radisson Hotel Groupyesim.dogukan@radissonhotels.com SOPHIE CLARKE, Director Social Media & Consumer PR, Radisson Hotel Group sophie.clarke@radissonhotels.com Radisson Individuals is a conversion brand that offers independent hotels and local regional chains the opportunity to be part of Radisson Hotel Group and benefit from the Group’s international awareness and experience with the freedom to maintain their own uniqueness and identity It is a complement brand to the other existing eight brands in the portfolio and an ideal first step for individual hotels with strong service scores who may be considering transitioning to one of the other successful core brands at a later stage Radisson Individuals hotels offer guests an opportunity to discover new locations around the world while always delivering Radisson Hotel Group’s high standards of quality and “Yes I Can!” service ethos combined with the local flavors and personality of the member hotels Radisson Individuals is a part of Radisson Hotel Group and prizeotel brought together under one commercial umbrella brand Radisson Hotels For reservations and more information, visit our website Radisson Hotel Group is one of the world's largest hotel groups with nine distinctive hotel brands and more than 1,700 hotels in operation and under development in 120 countries The Group’s overarching brand promise is Every Moment Matters with a signature Yes I Can The Radisson Hotel Group portfolio includes Radisson Collection including hybrid solutions placing guests and their needs at the heart of its offer Radisson Meetings is built around three strong service commitments: Personal while delivering on the brilliant basics and being uniquely 100% Carbon Neutral please click the box below to let us know you're not a robot Get the most important global markets news at your fingertips with a Bloomberg.com subscription Metrics details Members of the pentatricopeptide repeat (PPR) protein family act as specificity factors in C-to-U RNA editing The expansion of the PPR superfamily in plants provides the sequence variation required for design of consensus-based RNA-binding proteins We used this approach to design a synthetic RNA editing factor to target one of the sites in the Arabidopsis chloroplast transcriptome recognised by the natural editing factor CHLOROPLAST BIOGENESIS 19 (CLB19) We show that our synthetic editing factor specifically recognises the target sequence in in vitro binding assays The designed factor is equally specific for the target rpoA site when expressed in chloroplasts and in the bacterium E This study serves as a successful pilot into the design and application of programmable RNA editing factors based on plant PPR proteins These limitations justify examining the possibility of redesigning natural protein-guided editing systems such as those found in plants we aimed to target only one of the two editing events that are missing in clb19 thus attempting to design a synthetic editing factor that is more specific than the natural editing factor it is intended to replace Here we demonstrate that a synthetic editing factor of this type can be expressed in plants and in bacteria that it edits the chosen target RNA with high specificity and that it is at least partially independent of plant-specific cofactors The C at the editing site is shaded in blue Binding assays were performed with dsn3PLS (a MORF9 in the presence of 1 nM rpoA-78691 target RNA (a a Seedlings were grown under a 16 h photoperiod with a light intensity of either 100 µmol m−2 s−2 (left panel) or 40 µmol m−2 s−2 (right panel) The construct used to transform the clb19-3 mutant line is indicated on the left b Chloroplast transcript abundances are shown as log2 fold-difference compared to their levels in clb19 The RNA was extracted from plants initially grown under low light c RNA editing at the rpoA-78691 and clpP1-69942 sites in the four genotypes Partial editing of rpoA-78691 and no editing of clpP1-69942 was observed in three biological replicates of the plant line expressing dsn3PLS-DYW dsn3PLS-DYW is capable of editing rpoA-78691 but not clpP1-69942 Very little editing of rpoA-78691 was observed in the line expressing inactive dsn3PLS-DYW (E70A) The transgene transcript abundance was quantified using the RNA-seq data to verify to what degree differences in editing could be explained by variations in expression level (Supplementary Fig. S4) The lines with the highest transgene transcript abundance also showed the highest proportions of edited transcripts but the editing differences between the lines expressing CLB19 and dsn3PLS-DYW were much greater than the differences in transcript abundance This suggests that CLB19 is more efficient at inducing editing although it is possible that despite the lack of differences in transcript abundance the proteins may accumulate to different levels Despite the inclusion of a c-myc tag in the transgene constructs we were unable to detect either the CLB19 or dsn3PLS-DYW transgene products by western blot to verify this The only significant site where the log(odds ratio) exceeds 2 is the intended target site The ~492,000 sites below this threshold are indicated by the density contours (grey-black) From left to right: dsn3PLS-DYW(E70A) + MORF2 as a negative control; MORF2 and MORF9 enhance editing by dsn3PLS-DYW by similar amounts; a U at the rpoA-78691 editing position is not detectably reverse-edited to C; the clpP1-69942 site is not detectably edited with or without MORF2 All experiments were repeated in triplicate it is noteworthy that less than 1% editing at a single site is sufficient to give rise to phenotypic differences that could provide a selective advantage This might hint at how new editing events may arise and become selected for This type of data will be helpful for optimising future designs Hopefully this confirmation that MORF proteins act by enhancing RNA binding by PPR editing factors helps remove some of the confusion concerning the role of MORF/RIP proteins in RNA editing this work demonstrates the successful use of a synthetic PPR protein as an RNA-editing factor and lays the foundation for detailed structural and mechanistic studies into the mechanism of RNA editing Designer PPR proteins represent an attractive multipurpose scaffold for targeted RNA binding particularly as programmable RNA-editing factors the ‘high-light’ plants were germinated directly under 100 µE m−2 s−1 light to enhance the phenotypic differences between the lines leaves were harvested during the period of growth at 40 µE m−2 s−1 Escherichia coli strains used in this study were DH5α (Thermo Fisher Scientific, Waltham, MA, USA; https://www.thermofisher.com/) for cloning, BL21 (DE3) (Novagen, Merck KGaA, Darmstadt, Germany, https://www.merckmillipore.com/) for standard protein expression while labelled oligonucleotides were obtained from Integrated DNA Technologies (IDT Purified MORF2 and MORF9 protein was then concentrated using a Vivaspin 3 kDa MWCO concentrator (GE Healthcare) while purified dsn3PLS-DYW protein was concentrated using a Vivaspin 10 kDa MWCO concentrator (GE Healthcare) Concentrated protein was divided into 200 µL aliquots frozen in liquid N2 and stored at −80 °C until further use REMSAs were performed as described previously34 proteins purified were prepared on ice in a dilution series from 0.05–0.2 µM dsn3PLS-DYW or dsn3PLS-E2 or at a constant concentration of 0.1 µM dsn3PLS-DYW or dsn3PLS-E2 with a gradient of 0.1–0.5 µM MORF9 in 2 × REMSA binding buffer (85 mM Tris 1 nM of pre-heated diluted RNA oligonucleotide was added to the sample and incubated for 30 min at ambient temperature before loading onto a 5% polyacrylamide gel the fluorescence was visualised on an Amersham Typhoon system (GE Healthcare) with an excitation wavelength of 488 nm and an emission wavelength of 520 nm dsn3PLS-DYW (E70A) or CLB19 (34–500) were cloned into pCAMBIA1390 along with the sequences for the native CLB19 promoter (−1000 to −1) the N-terminal chloroplast targeting peptide from pea RbcS and a 4 × c-Myc epitope tag 5ʹ to the editing factor gene Expression plasmids were transformed into 2-month-old clb19−3 plants by floral dipping using Agrobacterium tumefaciens strain GV3101 RifR GentR Total RNA was isolated with RNAzol RT reagent (Sigma) from 3.5-week-old seedlings (T3) grown on half-MS plates under dim light conditions (40 µmol m−2 s−2) chloroplast and mitochondrial genomes as ‘decoys’ The libraries were sequenced on an Illumina HiSeq4000 sequencer by Novogene 29–34 million 150 nt paired-end reads were obtained for each sample The read data is available from NCBI (BioProject ID PRJNA680433) Analysis of the data was carried out as described above for the chloroplast RNA data except that the reads were mapped to the E coli BL21 genome (accession CP010816) and the relevant pETM11 and pETM20 constructs Nucleotide count data was analysed statistically with a Fisher exact test as implemented in the Python scipy.stats package and the p-values were corrected for multiple testing using statsmodels.stats.multitest.multipletests with the Simes-Hochberg procedure Odds ratios were used to calculate and visualise differences in editing as they are an estimation of the ratio of editing activities in the two samples being compared Odds ratios were calculated after adding a pseudocount of 0.5 to all observations to avoid division by zero All experiments were replicated at least once (and in triplicate where shown) Replicates are biologically independent samples (independent transformants) Functions and regulation of RNA editing by ADAR deaminases Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business Plant organellar RNA editing: what 30 years of research has revealed Towards a plant model for enigmatic U-to-C RNA editing: the organelle genomes editomes and candidate RNA editing factors in the hornwort Anthoceros agrestis The Expansion and Diversification of Pentatricopeptide Repeat RNA-Editing Factors in Plants Current strategies for site-directed RNA editing using ADARs A cytosine deaminase for programmable single-base RNA editing A pentatricopeptide repeat protein is essential for RNA editing in chloroplasts Redefining the structural motifs that determine RNA binding and RNA editing by pentatricopeptide repeat proteins in land plants Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins reveals their essential role in organelle biogenesis A hypothesis on the identification of the editing enzyme in plant organelles The cytidine deaminase signature HxE(x)n CxxC of DYW1 binds zinc and is necessary for RNA editing of ndhD-1 A conserved glutamate residue in the C-terminal deaminase domain of pentatricopeptide repeat proteins is required for RNA editing activity Cytidine deaminase motifs within the DYW domain of two pentatricopeptide repeat-containing proteins are required for site-specific chloroplast RNA editing A plant pentatricopeptide repeat protein with a DYW-deaminase domain is sufficient for catalyzing C-to-U RNA editing in vitro Plant-type pentatricopeptide repeat proteins with a DYW domain drive C-to-U RNA editing in Escherichia coli Extreme RNA editing in coding islands and abundant microsatellites in repeat sequences of Selaginella moellendorffii mitochondria: the root of frequent plant mtDNA recombination in early tracheophytes Chloroplast RNA editing going extreme: more than 3400 events of C-to-U editing in the chloroplast transcriptome of the lycophyte Selaginella uncinata Variable frequency of plastid RNA editing among ferns and repeated loss of uridine-to-cytidine editing from vascular plants Reverse U-to-C editing exceeds C-to-U RNA editing in some ferns—a monilophyte-wide comparison of chloroplast and mitochondrial RNA editing suggests independent evolution of the two processes in both organelles Fern genomes elucidate land plant evolution and cyanobacterial symbioses Improved computational target site prediction for pentatricopeptide repeat RNA editing factors Elucidation of the RNA recognition code for pentatricopeptide repeat proteins involved in organelle RNA editing in plants Comprehensive prediction of target RNA editing sites for PLS-class PPR proteins in Arabidopsis thaliana A combinatorial amino acid code for RNA recognition by pentatricopeptide repeat proteins Structural basis for specific single-stranded RNA recognition by designer pentatricopeptide repeat proteins AEF1/MPR25 is implicated in RNA editing of plastid atpF and mitochondrial nad5 and also promotes atpF splicing in Arabidopsis and rice Identification of two pentatricopeptide repeat genes required for RNA editing and zinc binding by C-terminal cytidine deaminase-like domains a pentatricopeptide repeat protein required for editing of rpoA and clpP chloroplast transcripts Multiple PPR protein interactions are involved in the RNA editing system in Arabidopsis mitochondria and plastids Two interacting PPR proteins are major Arabidopsis editing factors in plastid and mitochondria Predictable alteration of sequence recognition by RNA editing factors from Arabidopsis An artificial PPR scaffold for programmable RNA recognition The design and structural characterization of a synthetic pentatricopeptide repeat protein RNA-binding specificity landscapes of designer pentatricopeptide repeat proteins elucidate principles of PPR-RNA interactions McDermott, J. J., Watkins, K. P., Williams-Carrier, R. & Barkan, A. Ribonucleoprotein capture by in vivo expression of a designer pentatricopeptide repeat protein in Arabidopsis. Plant Cell https://doi.org/10.1105/tpc.19.00177 (2019) Modular ssDNA binding and inhibition of telomerase activity by designer PPR proteins Delineation of pentatricopeptide repeat codes for target RNA prediction MORF9 increases the RNA-binding activity of PLS-type pentatricopeptide repeat protein in plastid RNA editing Comprehensive high-resolution analysis of the role of an Arabidopsis gene family in RNA editing Multiple organellar RNA editing factor (MORF) family proteins are required for RNA editing in mitochondria and plastids of plants RNA editing in plants: Machinery and flexibility of site recognition The unexpected diversity of plant organelle RNA editosomes Design of stable alpha-helical arrays from an idealized TPR motif Structural basis for the modular recognition of single-stranded RNA by PPR proteins Arabidopsis chloroplast quantitative editotype Identification of critical nucleotide positions for plastid RNA editing site recognition Different patterns in the recognition of editing sites in plant mitochondria interacts with the protein RARE1 and broadly affects RNA editing The conserved domain in MORF proteins has distinct affinities to the PPR and E elements in PPR RNA editing factors Crystal structures of the Arabidopsis thaliana organellar RNA editing factors MORF1 and MORF9 Simplified screening for the detection of soluble fusion constructs expressed in E EMBOSS: the European molecular biology open software suite Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 Salmon provides fast and bias-aware quantification of transcript expression and robust method for rRNA depletion in RNA-sequencing studies interactive logos representing sequence alignments and profile hidden Markov models Download references This research was supported by the Australian Research Council (grants FL140100179 to I.D.S DP150102692 and DP200102981 to C.S.B and I.D.S. DE150101484 to B.G.) and the CSIRO Synthetic Biology Future Science Platform (fellowship to S.H.) Australian Research Council Centre of Excellence in Plant Energy Biology Lilian Vincis Pereira Sanglard & Ian Small wrote the manuscript with input from all co-authors The authors declare no competing interests Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Download citation DOI: https://doi.org/10.1038/s42003-021-02062-9 Anyone you share the following link with will be able to read this content: a shareable link is not currently available for this article Sign up for the Nature Briefing newsletter — what matters in science his day job dedicated to protecting the environment and studied Physics and Philosophy in the UK French language and civilization in France and Mexican literature of the 20th century in Mexico  His short stories have appeared in Coffin Bell I never thought I could fall in love with concrete or even find it aesthetically pleasing, but Notre-Dame de Royan changed that with progressively taller columns edging higher until the final two pierce the sky presumably to guide souls and prayers to the heavens The shapes are like a constellation of vertical razor clams stabbing razor clams into the sand forming a model from the shells of life for this later masterpiece that is the city’s landmark.  An alternative attractive interpretation of the vertical elements is that they are like organ pipes I doubt the inspiration was as innocent as shells More likely that the structure was inspired by the horror of the amassed shards of broken buildings that the church finally replaced in 1958.  The overall is shape is that of a giant yet elegant oval with the bell tower standing proudly at the front top though beautifully and subtly patterned with columns of small square windows (black from the outside) a typical form of Royan’s architecture and a series of longer rectangular deep-blue windows No bright colours are visible in this monument that filled me with awe and curiosity.  Both churches are reminders of the contemporary European tragedy of the Russian war in Ukraine and the mindless destruction includes a grille of six blue lines that project beyond the face that give the building its name Le Grille Pain also employs a series of small square openings for light that echo those of Notre-Dame de Royan and an outside staircase typical of Royan but with a unique blue disc as a type of parasol also by Pierre Marmouget is one – a house shaped after its name metal stairs that go from first floor to the pool like a giant mouth waiting to be fed fire and food and moving blue and yellow walls that remind me of the Ukraine A multi-coloured phoenix emerged in the decades following Royan’s destruction What will emerge from the current war zones in Ukraine when the current nightmare has finally passed how will the Ukrainians rebuild and build a future and wonder what future is possible for the Ukraine.  Essential cookies enable basic functions and are necessary for the proper function of the website Statistics cookies collect information anonymously This information helps us to understand how our visitors use our website Advocates for ideas and draws conclusions based on the interpretation of facts and data Translations may contain inaccuracies—please refer to the original content The news came just days after the United Nations Assistance Mission in Afghanistan (UNAMA) renewed its mandate for the twentieth time signaling the U.N.'s continued commitment to supporting Afghan human rights and well-being But Afghans and those who want to help face a world that has largely moved on from Afghanistan just as the country grapples with more hunger poverty and persecution than it has at any other time since 2002 In addition to setting in motion events that have brought millions of Afghans to the brink of starvation the fall of Kabul in August 2021 was effectively the death knell of democracy human rights and prosperity in Afghanistan most acutely for Afghan women and minority groups while I am grateful that many vulnerable Afghans were evacuated though they go largely unreported as the Taliban controls the national media and the international media has shifted its focus Brave Afghan women leaders and activists and members of the Hazara community—Afghanistan's Shiite ethnic minority—and other minorities have been silenced They are focused on sharing information and analysis with Afghan women leaders and activists outside the country in the hope that these stories will reach the international community and compel leaders to act Reported cases of suicide among Afghan women have increased dramatically While some women have undoubtedly died by suicide out of despair and hopelessness the activists in Afghanistan that I am in touch with believe that many of these women are being murdered by their families Domestic violence has increased under the horrendous economic conditions and food shortage Afghans have faced since August Women who have been arrested by the Taliban for being outspoken are sometimes subjected to sexual abuse while detained and the perceived shame from these events can lead families to commit honor killings While the world has heard the heartbreaking stories of young girls being sold into marriage Hazara girls are also regularly being disappeared and murdered two young Hazara girls in Balkh province were murdered and the dead body of an 11-year-old Hazara girl was found on a street in western Kabul who both previously served as police officers intimidating and murdering women in an attempt drive them out of all professions outside the household The Taliban is also raising revenue by conducting raids on Tajik and Hazara homes in Kabul claiming they are searching for illegal arms and then requiring pay offs to not report families for alleged contraband The Taliban is also manipulating humanitarian aid distribution to cut out women and ethnic minorities, while prioritizing themselves and their supporters. Local Afghan media estimated that historic Hazara communities in Bamyan and Daykundi provinces receive just 2 percent of aid available in the country despite representing a larger share of the population Aid distribution to Hazaras has ceased completely in the heavily Hazara neighborhood of Dasht-e-Barchi in western Kabul the international community has failed to do anything about it the United Nations and the broader aid community played an important role in strengthening Afghanistan's institutions monitoring human rights and coordinating humanitarian assistance Although the collapse of the former Afghan government has made the job of UNAMA and other aid groups much harder than ever before it also made their work even more critical many countries around the world have spoken about how much they support Afghan women and Afghan women's rights but we haven't seen that translate into action women's organizations and members of the Hazara community and other marginalized groups as partners who can help inform It also means implementing a mechanism for monitoring equitable humanitarian aid distribution to ensure the most at-risk groups in Afghanistan don't also face the biggest barriers to accessing aid Although the history of the U.S.-led war in Afghanistan may already be written the fate of millions of Afghan women and ethnic and religious minorities is not we need the international community to not turn away Yalda Royan is an Afghan women's rights activist who leads the Afghanistan country practice for VOICE Amplified a nonprofit focused on combating violence against women and girls around the world The views expressed in this article are the writer's own Newsweek is committed to challenging conventional wisdom and finding connections in the search for common ground Newsletters in your inbox See all The World Flying Disc Federation (WFDF) began organizing the World Beach Ultimate Championships (WBUC) in 2011 A relatively newer discipline of the sport beach ultimate features smaller teams (5 vs While the environment might suggest a more laid back vibe the focus and intensity displayed by participating athletes competing for world titles is anything but USA Ultimate will host tryouts for the event’s three elite divisions (men’s mixed and women’s) while fielding additional age-restricted teams in a variety of masters categories Team USA’s success on the grass has carried over onto the sand the men’s and women’s teams enter the next edition as defending world champions while the mixed squad will look to upgrade its bronze medal from 2023 they’ve combined for 12 medals in the last four tournaments – nine gold View View View View View View View View View View View View View View View View View View View View View View View View View View View View View View View View View View View Northwestern Medicine | Northwestern University | Faculty Profiles News Center when false information about the virus began to spread on Twitter physicians and scientists from Northwestern Medicine and other institutions banded together to combat the deadly misinformation and disinformation and support one another when they ultimately were attacked online for doing so.  Royan and fellow medical professionals explain how successful this group has been and why it is an effective tool to disseminate accurate medical information and combat disinformation while minimizing the harm related to personal and professional harassment that can come with social media advocacy “The pandemic has been really taxing for health professionals,” said Royan (@reginaroyan), an emergency medicine research fellow and clinical instructor of Emergency Medicine “In addition to the emotional toll caring for these very sick patients particularly in the early waves of the pandemic the politicization around COVID-19 added another layer of stress for many of us One thing we highlight in this paper is that these kind of groups can be a safe space for health professionals to talk about issues like harassment on social media to keep the fight against misinformation going.” IMPACT and other health professional amplifiers are comprised of nurses, health economists, scientists, public health professionals and physicians, Royan said. They’ve endured public harassment and attacks after posting scientifically proven medical information about the COVID-19 virus and vaccines IMPACT has also created numerous easy-to-digest infographics in both English and Spanish around specific issues such as the effectiveness of masking and social distancing and how mRNA was used to create the Pfizer-BioNTech and Moderna COVID-19 vaccines It is a creative way the group is trying to reach people who may not have been reading accurate health information “We know that COVID-19 has disproportionately affected the Latino population and it’s been important to us to partner with community organizations like Illinois Unidos to ensure that we are also addressing misinformation with Spanish-language resources,” Royan said.   The group has recently begun to combat false information about reproductive health issues following the U.S. Supreme Court’s overturning of Roe v. Wade. They’ve also started disseminating information about firearm injury, such as a recent tweet that stated “Fact: Mental illness is not an effective predictor of gun violence against others.” IBM Security shares his thoughts on major security challenges faced by organisations amidst today’s complex security environment and how can organisations leverage IBM AI powered QRadar Suite to improve their cybersecurity postures By commenting, you agree to the Prohibited Content Policy By continuing you agree to our Privacy Policy & Terms & Conditions About Us Contact Us Newsletters Royan Kamyar, M.D., MBA When I graduated from medical school in 2006 I was completely unaware there was a “preventive medicine” residency Primary care was largely ignored by highly competitive students looking for the best salaries and lifestyles The emphasis from mentors and peers was always on the “ROAD” to success: radiology Outside of a single guest lecture I received from Dr. Dean Ornish during my second year “prevention” as a field was minimized to vaccinations mammograms and colon screenings… In other words just those interventions that somehow triaged into a business model After recently attending the American College of Preventive Medicine’s 63rd annual conference in Portland I’m sorry to report the landscape is largely unchanged chiefly in the form of poorly aligned reimbursement models continue to reign as the decision-making framework that guides the future of the medical profession and patients’ lives Physicians are still under the gun of dubious insurance practices and now a growing pool of unstructured data The most forward-thinking leaders of the group are calling for a focus on “outcomes” to guide reimbursement and policy models rather than fee for service models of the past While this is undoubtedly a positive next stage of our evolution as an industry what strikes me as consistently missing from these discussions is any real focus on the patient-physician relationship. In the daily practice of healing is there no room to explore the power of human-to-human interaction?  aside or lost cause… In the days of RVUs and number of patients seen per hour as core administrative policies driving hire and fire decisions… perhaps this is to be quietly accepted I couldn’t help but feel there is a large hole in the room TEHRAN – Royan Research Institute ranked among the world's top 10 centers based on the total number of publications investigating male infertility and assisted reproductive techniques (ART) during 2000 to 2019 based on the results of a study published in the international journal Andrologia The article by researchers from eight American Asian and European countries evaluates the total number of publications in male infertility and ART from 2000 to 2019 ART is considered one of the main options in treatment and Royan Research Institute is one of the world leaders in this field The results are obtained from the analysis of twenty years of work by researchers worldwide evaluating the number of articles The research shows that Iranian researchers have had good collaborations with others in the international arena which is an important issue in the future of the research process.  it has been shown that the trend of this type of research in the last twenty years has always been constant and azoospermia (obstructive / non-obstructive) has been the most field of clinical studies (more than 60 percent).  using assisted reproductive techniques has reported over 47 percent success assisted reproductive technologies currently play a special role in treating men's infertility non-profit organization affiliated with the academic center for education Royan is a research institute for reproductive biomedicine and infertility treatments; and a world's leading one in both research and treatment of this field The institute also acts as a stem cell research leader and is one of the best clinics for infertility treatment It has 46 scientific members and 186 lab technicians said in October that foreign couples from neighboring and even European countries highly welcome infertility treatment in Iran because of the favorable cost and successful test results compared to other countries Infertility is the inability to become pregnant after one year of intercourse without contraception involving a male and female partner including some that medical intervention can treat.   Infertility occurs in 10 to 15 percent of couples Causes of infertility can be female or male Male infertility is responsible for 40 percent of infertility cases while 40 percent are due to female infertility and 10 percent are due to combined problems in both parts both people do not have a problem according to the available tests but they do not have children for unknown reasons great strides have been made in diagnosing and treating infertility and about 65 percent of infertile couples have had children using new methods about 10 to 15 percent of couples are infertile these couples went to European countries for treatment but we entered into this issue in time and established more than 70 infertility centers The cost of infertility treatment in Iran is about 50 percent lower than in European and American countries And the success rate in the best centers is between 30 and 40 percent Today marks the 80th anniversary of the liberation of Auschwitz-Birkenau Roma and communists were murdered by the Nazis But today’s commemoration was tarnished by the hypocrisy of western imperialism allegedly to commemorate the lives lost in the fight against Nazism the Allied leaders played an insignificant role in defeating fascism compared to the struggle and sacrifice of the Soviet people Today is the 80th anniversary of Operation Barbarossa the German invasion of the Soviet Union in World War Two which claimed the lives of almost 5m Soviet troops and saw the Nazis plunge deep into Soviet territory was facilitated by the wrecking behaviour of Stalin and the bureaucracy.