By subscribing I accept the terms of use and privacy policy bring the total number of murders in Israel's Arab community since the start of the new year to 48 2025Get email notification for articles from Deiaa Haj Yahia FollowMar 9 2025Two Arab men in their 30s were shot to death early Sunday morning in the Arab Israeli municipalities Zemer and Kafr Qara The School of Maths welcomes new Associate Professor Zemer Kosloff Zemer Kosloff received his PhD from Tel Aviv University in April 2014 Following a 3 year postdoctoral position at the University of Warwick he joined the Hebrew University of Jerusalem in 2016 where he worked until his arrival in Bristol as a new Associate Professor dynamical systems and probability theory with an emphasis on the study of non-stationary systems Staff and PGR intranet More social media After weeks of rumors, US chip giant Qualcomm Technologies today announced that it has acquired Israeli 5G mobile network automation company Cellwize Wireless Technologies Qualcomm said that the acquisition will further accelerate its leadership in 5G Radio Access Networks (RAN) innovation and adoption Qualcomm added that Cellwize’s 5G network deployment and management software platform capabilities would strengthen its 5G infrastructure solutions and fuel the digital transformation of industries and support the growth of the cloud economy No financial details about the acquisition were disclosed but market sources believe that Qualcomm is paying $300-350 million for Cellwize a reasonable return for a company that has raised $75 million from a range of investors including Viola and Vintage as well as chip giants Intel Deutsche Telekom and Green Apple will see the biggest returns including 110 in its Ramat Gan development center will receive incentive bonuses worth tens of millions of dollars if they commit to continue at the company Cellwize was founded in 2013 and until 2018 developed just one product - a system for optimizing and self-organizing automated networks (SON) The company's customers were mainly small companies from Asia and Latin America Viola founding partner Shlomo Dovrat replaced the venture capital funds representative on the board with Doron Inbar A new strategy was introduced which catapulted the company into the world telecom mainstream with its 5G mobile network automation Cellwize CEO Ofir Zemer will become Qualcomm VP product management "We are excited to join Qualcomm Technologies as we are both committed to accelerae the mission to modernize Radio Access Networks and enable mobile network operators and enterprises to fully realize and monetize their digital transformation." Published by Globes, Israel business news - en.globes.co.il - on June 13 © Copyright of Globes Publisher Itonut (1983) Ltd. A Toronto District School Board sign is shown in front of a high school in Toronto on Tuesday Much like the September 11, 2001, terrorist attacks by al Qaeda in the US—9/11 to many of us—the 10/7 terrorist attack in Israel by Hamas changed everything. In both cases, the localised events were catastrophic killing over a thousand innocent civilians the events sent shockwaves reverberating around the world Jews in most Western cities weren’t as shocked by the terrorism itself as they were by the rapid explosion of antisemitism in its newest guise of anti-Zionism Perhaps even more shocking was the tepid response by decision-makers who enabled its expansion through their acts of omission and incorporating values of diversity and inclusion “Fighting Antisemitism: Standing with Israel” and shows “an Israeli flag clearly displayed” on a young girl The oppositional parents also took the liberty to share their deep knowledge of the Middle East conflict by defining anti-Zionism for our Jewish community: “Anti-Zionism is the rejection of colonialist racist apartheid political sentiment rooted in legitimation of occupation of Palestinian land which anybody with a lay understanding of anti-racism anti-oppression and human rights cannot deny.” It was interesting as Jews to be educated by non-Jews as to what hatred towards us actually was Any other group would be condemned by the TDSB for attempting to define another group’s understanding and definition of racism against themselves it ruled that Palestinians had a “plausible right” to be protected from genocide and that South Africa had the right to present its claim to the court We believe that all people should be protected from genocide and political violence and that all civilian casualties of war and terrorism are tragic But the ICJ rulings are a far cry from the common accusation that Israel is directly and intentionally committing genocide and we must remember that the proximal cause of both Israeli and Gazan suffering in this conflict is Hamas What these parents are really trying to say is that the problem with FSWC is that it’s Zionist It stands for the right of the Jewish people to self-determination in their ancestral homeland of Israel What they won’t plainly say is that they oppose this right of the Jewish people and they oppose Israel’s right to exist as a Jewish state Police investigate the Yeshiva Gedolah school for clues after shots were fired at two Jewish schools Thursday Montreal police say two Jewish schools in the city were hit overnight by gunshots Police say nobody was inside at the time of the shootings Gili Zemer is a concerned mother of three Jewish children in the TDSB and an entrepreneur David Mandel is a Toronto-based cognitive psychologist with two children in the TDSB PLATINUM Corporate & Industry Council Members: Little Stars, Big Voices Zemer Gitai, Fenna Krienen, Michael Skinnider Every year, the National Institutes of Health selects a handful of researchers performing innovative blue-sky scientific research to receive funding through its High-Risk, High-Reward Research program Nobel laureate John Hopfield, an emeritus Princeton professor whose work transcended departmental boundaries, celebrated that kind of scientific research in a press conference Tuesday following the announcement of his 2024 Nobel Prize in physics noting that “the kind of science which has such extensive possibilities [also has] the possibility that you just don’t find anything at all This year, the NIH awarded $207 million in grants to 67 high-risk, high-reward biomedical and behavioral researchers, including four at Princeton: John F. Brooks II, Zemer Gitai, Fenna Krienen and Michael Skinnider Graduate alumna Rong Lu to pursue her research at the University of Southern California where she is an associate professor of stem cell biology and regenerative medicine. The goal of these NIH Director’s Awards is to “enable exceptionally creative scientists to potentially transform biomedical science,” according to the organization. “The High-Risk, High-Reward program champions exceptionally bold and innovative science that pushes the boundaries of biomedical and behavioral research,” said Tara Schwetz, deputy director of the NIH for Program Coordination, Planning, and Strategic Initiatives in the awards announcement “The groundbreaking science pursued by these researchers is poised to have a broad impact on human health.” the Director’s Pioneer Award has encouraged researchers at all stages of their careers "to pursue new research directions and develop groundbreaking high-impact approaches to a broad area of biomedical behavioral or social science," the announcement said Gitai’s achievements have been recognized by many prestigious awards including a previous Pioneer Award in 2015 the Human Frontier Science Program’s Young Investigator Award in 2013 and the Beckman Young Investigator Award in 2007 he was elected into the American Academy of Microbiology the New Innovator Award supports “unusually innovative research from early career investigators,” according to NIH which defines "early career" as being within 10 years of a researcher's education. Brooks joined the Princeton faculty in January 2022 after completing a Ph.D in microbiology from Northwestern University and a B.S in microbiology from the University of Michigan He also performed postdoctoral studies at the University of Texas-Southwestern in the laboratory of Lora Hooper Gray Fellowship from the Howard Hughes Medical Institute (HHMI) a Pew Biomedical Scholar Award and a Hypothesis Fund Award Krienen is an assistant professor in the Princeton Neuroscience Institute and affiliated faculty in Quantitative & Computational Biology. Her research focuses on the outsized development of the human neocortex the part of the brain responsible for advanced cognitive abilities like language Humans have a much larger neocortex than other primates, allowing for enhanced cognition but also making humans more vulnerable to neurological disorders like autism and Alzheimer’s disease. The NIH funding will support Krienen and her research team as they investigate how genomic recording systems "reveal evolutionary modifications in the primate neocortex." She came to Princeton in 2022 after completing an undergraduate degree at UC-Berkeley at Harvard University and a postdoctoral fellowship with Steve McCarroll at Harvard Medical School and the Broad Institute Krienen’s previous awards include a 2023 Klingenstein-Simons Fellowship from Klingenstein Philanthropies and the Simons Foundation a 2020 Next Generation Leader award from the Allen Institute and a 2019 Bridge to Independence Fellowship from the Simons Foundation Autism Research Initiative the NIH Early Independence Award has provided funding to allow “exceptional junior scientists” to bypass a traditional postdoctoral fellowship and launch independent research labs Skinnider is an assistant professor in the Lewis-Sigler Institute for Integrative Genomics and an assistant member of the Ludwig Institute for Cancer Research Princeton Branch He investigates the small molecules in the human body that collectively influence our risk of disease and determine how we respond to prescription drugs the vast majority of these small molecules remain unknown — the “dark matter” of the metabolome Skinnider came to Princeton in 2023 after receiving his undergraduate degree from McMaster University and his M.D./Ph.D. from the University of British Columbia. He also spent time as a visiting Ph.D. student at the École Polytechnique Fédérale de Lausanne. His previous honors include the 2023 Young Explorer Award from the journal Science and the NOMIS foundation, the 2022 International Birnstiel Award, the 2021 Scholarship in Molecular Medicine from the Dan Davis Foundation and the 2020 Borealis AI Fellowship. He was also selected for the 2020 Forbes 30 under 30 list and the 2024 cohort of the “Talented 12” early career researchers by Chemical & Engineering News. This website is using a security service to protect itself from online attacks. The action you just performed triggered the security solution. There are several actions that could trigger this block including submitting a certain word or phrase, a SQL command or malformed data. You can email the site owner to let them know you were blocked. Please include what you were doing when this page came up and the Cloudflare Ray ID found at the bottom of this page. With the emerging field of artificial intelligence (AI) becoming increasingly relevant to our everyday lives Jewish Action hosted a conversation between Rabbi Dr a professor in the Neuroscience Program at Bar-Ilan University and a longtime columnist of Jewish Action rabbinic head of the Jerusalem College of Technology (JCT) to understand some of the implications of this technology and its impact on halachah Rav Rimon serves as a rav in Alon Shevut Darom and teaches classes in halachah at Yeshivat Har Etzion He also teaches at the Herzog College and at the Beit Midrash for Women in Migdal Oz Rav Rimon was awarded the Moskowitz Prize for Zionism on Yom Yerushalayim in 2014 for his monumental project JobKatif on behalf of the Jews of Gush Katif Rav Rimon is opening a beit midrash that will research the application of halachah to the newest technological developments Zivotofsky for assisting in the preparation of this article Ari Zivotofsky: Webster’s Dictionary defines artificial intelligence (AI) as a branch of computer science dealing with the simulation of intelligent behavior in computers there have been tremendous developments in this area to the point that they can extrapolate and deduce AI uses computer algorithms to arrive at conclusions Will AI limit the role of doctors by making predictions and diagnoses can we rely on a computer to make medical decisions Rabbi Yosef Zvi Rimon giving a talk on AI and halachah at the OU’s Torah New York 2019 event held this past September at Citi Field Rabbi Yosef Zvi Rimon: This is an excellent question there has been extraordinary progress in this area and AI has become increasingly intelligent over time IBM’s chess-playing program Deep Blue beat world chess champion Garry Kasparov The principles of the game were programmed into the computer which masterfully won the match by blindly searching through millions of moves Google’s AI subsidiary DeepMind devised AlphaZero Given no (“zero”) human input aside from the rules of chess it beat the world’s best chess-playing computer program after continuously playing chess against itself for a mere four hours; it played the game millions of times and learned from its mistakes AlphaZero is regarded as the best chess player in the world—human or computer—and when playing AI no longer just acquires knowledge; it arrives at conclusions on its own (mevin davar mitoch davar) AI is no longer just feeding information into one big database There’s no question that AI is becoming increasingly sophisticated and is able to perform human activities with greater speed and efficiency AI is being used to spot lesions on mammograms and AI systems are being developed to diagnose whether or not one will develop Alzheimer’s disease or other diseases later in life Scientists are also working on developing algorithms that will help them make decisions about cancer treatment A doctor may know how to interpret X-rays and can be well versed in the most current research but computers have access to far more data and therefore arrive at much more precise conclusions Based on the trajectory of today’s research one can envision that there will come a day when artificial intelligence will be making most medical decisions and a doctor has something that AI lacks—human intuition What about teaching a robot to do nikkur achorayim (the removal of certain large blood vessels cheilev [prohibited fats] and the gid hanasheh [sciatic nerve] after a kosher animal is properly slaughtered and inspected) What about teaching a robot to check articles of clothing for traces of shatnez RR: I don’t see why checking for the presence of shatnez—wool and linen mixed together in an article of clothing—would be a problem No special kavanot (concentration of the mind in performance of a religious act) are required nowhere in the Torah is it written that a human being must do the checking a robot should be able to do nikkur achorayim; however the actual shechitah (the Jewish religious and humane practice of slaughtering animals) must be done by a God-fearing Jew The Shulchan Aruch (Yoreh Deah 2:11) rules that shechitah is only acceptable if it is done by a human being Thus it should be clear that shechitah may not be done by a robot See also siman 7:1 where the Shulchan Aruch explicitly states that shechitah may not be done by a machine that is not directly operated by a human Could a computer check the sharpness of the shochet’s (ritual slaughterer) blade It must be exquisitely smooth and exceedingly sharp The Shulchan Aruch states that one must check the knife b’kavanat halev (with mindful concentration) twelve times (YD 18:9) A laser could be used to check the sharpness of the knife but cannot serve as the the final arbiter because a human being has to do the checking issue a warning to the schochtim indicating the knife is too dull RZ: Video cameras are used for certain aspects of kashrut supervision they are used to verify that the milk produced is cow’s milk and that it was not extracted in violation of Shabbat If a robot could be programmed to learn what’s important in a kosher kitchen such as not mixing meat and milk and using only kosher-certified products would it be acceptable to use robotic mashgichim there is no requirement that a mashgiach has to be physically present The halachah wants to ensure that a proprietor does not do anything improper The halachic requirement is “mirtat,” which means that the proprietor has to be afraid that he will be caught and will suffer the consequences if he tries to do something improper Assuming a robot is observing and recording what is taking place because if there are no consequences [for violating kashrut standards] RZ: Our discussion until now centered on today’s technology Let’s spend a few minutes discussing future technology enables users to interact with computers via brain activity or “thinking” only One use of BCI is to enable people with paralysis and other disabilities to control robotic arms or other devices by thinking about such actions the wiring together of brains and computers is actually a reality and companies have invested millions of dollars in moving progress along in this area It is very likely that one day our brains might be able to interact with our smartphones or tablets—and we will be able to turn an oven or light switch on simply by thinking about it can one theoretically fulfill a mitzvah simply by thinking about it can one violate Shabbat by merely thinking about doing a forbidden act RR: The well-known Shabbat zemer “Mah Yedidut” states v’gam lachashov cheshbonot/ hirhurim mutarim ul’shadeich habanot—[On Shabbat] your non-Shabbat desires are prohibited as is performing business calculations/ but pleasant thoughts are permitted The question is—what types of “thoughts” are permitted on Shabbat There are several Torah sources that define thought One such source is found in Tosafot in Masechet Gittin 31a which discusses separating terumot and ma’aserot (tithes) by “thought” on Shabbat Can one actually separate terumot and ma’aserot simply by thinking about it There is a machloket Acharonim on how to understand this Tosafot According to Rabbi Shlomo Zalman Auerbach it is forbidden to separate terumot and ma’aserot in this manner [on Shabbat] I don’t think BCI would be permitted for general use on Shabbat; however if we’re talking about an individual who is paralyzed and BCI [can enable him to move his limbs on Shabbat] RZ: What about fulfilling positive mitzvot through brain-computer interface can one use BCI to lift the arba minim or even to give a ring to a woman in order to betroth her RR: Since one can be mekadesh (betroth) a woman even through a shaliach using BCI for this purpose may not be a problem using BCI to fulfill a positive commandment is another matter an individual using BCI has not actually performed an action because the computer is an intermediary directing his hand or artificial limb the individual’s thoughts are controlling the movements and perhaps that suffices to fulfill the mitzvah would we be able to rely on it for mitzvot that require the involvement of a human being I believe that with regard to the issue of fulfilling a mitzvah via BCI each and every mitzvah would have to be discussed and evaluated separately RZ: We’ve touched upon the connection between AI and almost all four parts of Shulchan Aruch What about nezikin [tort law] in Choshen Mishpat that a self-driving car causes harm to property—or Although there may have been a human in the car an autonomous system—AI—was in full control of the vehicle The company testing the car’s capabilities RR: I was actually asked this very question after a self-driving vehicle did indeed kill someone it is understood that when a person is controlling a steering wheel in a conventional car The case is classified as “adam hamazik,” an individual who caused harm It then needs to be determined whether the driver killed the individual by accident—in which case he would be liable for the Torah’s punishment of exile in an ir miklat [city of refuge]—or if he did so intentionally—in which case the beit din would determine his punishment and therefore the halachic category of adam hamazik does not apply; rather the category of “mamon hamazik,” property that causes damage This is similar to a case where a bull gores a person and injures him which is classified as “mamon shehizik.” Assuming the autonomous car has the status of mamon shehizik It would seem that the owner of the car would have to take responsibility unlike the cases of mamon hamazik discussed in the Gemara There is someone out there who programmed the car.” One could counter that as the owner he was obligated to ensure that the programmer’s work was up to standard and if he did not do so and his property caused harm The underlying question here is how halachah defines the basis of the owner’s responsibility for damage caused by his property Is an owner inherently responsible for damage caused by his property unless there are circumstances beyond his control he would be responsible for damage caused by a self-driving car unless he can prove there were extenuating circumstances Or is he only responsible for damages that were caused due to negligence on his part he didn’t take sufficient security measures to ensure his animal or property would not cause damage it would have to be determined that there was some degree of negligence RZ: Do you see a future where a robot or computer will be comparable to a human being there is a debate in the scientific community as to whether or not we can actually develop the technological know-how to manufacture a robot that will be able to think on its own Some scientists believe this will happen; others say it will never come to be would we be able to rely on it for mitzvot that require the involvement of a human being A robot could never be considered a human for the purposes of joining a minyan And even if it were to write in the most beautiful manner and in the most precise way the Torah requires a Jewish person with da’at (understanding) Even if a robot had sechel (intellect/brainpower) A robot can never attain the status of a human being and therefore it cannot perform these religious functions RZ: What about future smart homes and Shabbat it will most likely fulfill residents’ wishes before they are even aware of them Imagine entering your dining room in a future smart home Your smart home has learned all about you and is aware that you entered the room It knows the kind of music you prefer and starts playing your favorite songs it recognizes that you are thirsty and prepares a cup of coffee Eventually there may be sensors all over the home—sensors in the refrigerator will detect that you are running low on breakfast foods and will place an order online; sensors in the medicine cabinet will check if you have taken your pills How will we deal with all of this on Shabbat let’s begin with sources in the Gemara that deal with “davar she’eino mitkaven,” unintended consequences of a permitted action the Gemara presents a disagreement between Rabbi Shimon and Rabbi Yehudah Rabbi Shimon says: A person may drag a bed a chair or a bench on the ground [on Shabbat] provided that he does not intend to make a furrow Rabbi Yehudah says: No vessels may be dragged since the furrow that is created is a davar she’eino mitkaven; he had no intention to plow This is similar to another Gemara that discusses one who sees a gazelle in his house Shabbat 107a) responds with the following: In Yerushalmi [13:6] it appears that from the outset they permitted him to lock his house This is because even though doing so will trap the gazelle inside since he needs to protect his home it is permissible as long as he did not only intend to trap the gazelle It would appear that intent plays a pivotal role in determining whether or not an act constitutes a violation of Shabbat Let’s look at a more contemporary illustration of this principle: Say your neighbor has a light sensor in his front yard and if you pass by the house the sensor will detect movement and the light will go on Can you pass by your neighbor’s house on Shabbat Rabbi Shmuel Wosner writes (Shevet Halevi 9:69) that as long as your intention is not to go there to turn on the light Now let’s examine our original question of smart homes and sensors on Shabbat The fact that AI sensors are continually learning about you even as you move around your home on Shabbat does not necessarily constitute a violation of Shabbat (since it is an unintended consequence of your actions) suppose you go downstairs to your kitchen on Shabbat morning and after a few minutes the shutters suddenly open and the coffeemaker begins preparing coffee because your smart home “recognizes” that at that particular time and temperature you like the shutters open and a coffee ready—that would be problematic This is because AI is doing a forbidden melachah (cooking) a greater concept at play here that should be discussed There are certain activities that the rabbis forbade on Shabbat even though they are Biblically permissible because they have the potential to destroy the nature of Shabbat A religious man I know has a very successful Internet reputation management business a client in New York was desperate to reach him It was an “emergency.” She e-mailed him and did not receive a response I lost thousands of dollars today!” He explained to her that it was Shabbat “So what do you do on Shabbat?” asked the woman and we eat a meal with our family,” he replied “Our Shabbat meal can take two hours—we sit together with our children “I try to gather my family together for a meal so we can have some quality time but even if I finally succeed in getting everyone to sit down together Then one child gets a WhatsApp message and is distracted Another child gets a text and leaves the room Can you please give me the formula for Shabbat?” while it can sometimes seem as if halachah closes doors allowing one to enter areas that would otherwise be inaccessible A teenager once told me that by 4:00 pm on Shabbat afternoon he could no longer hold out without his phone “You have a serious problem if you cannot be alone with yourself for twenty-four hours no to the Internet; but through Shabbat you open doors to yourself I believe in the derech of Rabbi Avraham Yitzchak HaKohen Kook who embraced progress and felt that technological advancements are positive overall the fallout of being available all the time is not a positive development; it means that one is always distracted and never focused We must be wary of turning Shabbat into a yom chol It is up to our generation’s posekim to assess technological advances and to determine what is allowed and what is forbidden and when heterim are detrimental to upholding the sanctity of Shabbat Shabbat is the only time we close all our doors and stay focused on the truly important things in our lives More in this Section: Rabbi Tzvi Ortner: The Solution Finder Miri Eliahu could not speak; her voice became a squeak that frightened her grandchildren Then she found her way to the Hadassah Medical Organization's Voice Clinic and within 81 minutes When this young grandmother’s cough and laryngitis didn't seem to go away She also saw a local speech therapist for months Eliahu went from being an outgoing and vivacious woman to a silent one Eliahu was suffering from aphonia," explains Dr “Aphonia can be a confusing and difficult disorder to diagnose for doctors who haven't seen it and even more difficult for patients you may feel helpless and even simple tasks like swallowing food may prove painfully inconvenient there are several treatment methods dependent on the severity of the case Eliahu began treatment with Speech Therapist Sherry Lotem Landau Zemer explains why these exercises are so important: "You know how people always tell you not to whisper when you are losing your voice That's not because it's going to hurt your vocal cords That's because whispering can teach your brain to change the way you speak so that you don't use your voice properly There's a change in the brain that needs to be overcome--and can be overcome with correct exercises First you show that a person can make sound the vocal cords relapse to the correct way of working.” Landau Zemer recalls that she once had a patient who moved to Israel from the United States “He hadn't spoken for a year and a half,” she said “He came to Hadassah ten days into his Aliyah for help He carried a pad everywhere and wrote what he had to say "I heard my voice and asked if that was really me,” relates Mrs “Do you recognize this voice?” she asked him telling you that there has been a miracle--a Hadassah miracle.” The Women's Zionist Organization of America and Hadassah the Power of Women Who Do are registered trademarks of Hadassah Colossal From her Baltimore studio, Israeli artist Zemer Peled (previously) sculpts countless spikes and oblongs into densely textured artworks Amorphous forms bristle with porcelain pieces of varying shape and hue mimicking organic elements like coral reefs and intertwined vines Other sculptures depict oversized blooms with the firm pointed edges of each shard directly contrasting the soft and fleshy petals found in nature and head to her site to see her recent coronavirus-themed pieces Do stories and artists like this matter to you? 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See our Terms of Service and Privacy Policy Eylon Zemer is currently the compliance manager at Caledonian Global Financial Services in Toronto where he also serves as a director Caledonian has a global presence with offices in New York the British Virgin Islands and Grand Cayman where it was established over 40 years ago It has recently been awarded “Best Offshore Bank Cayman Islands” and “Best private bank” by World Finance Zemer plays an integral role in Caledonian’s global compliance and anti-money laundering effort by providing expertise in offshore and private banking His responsibilities involve implementing internal policies and procedures across multiple lines of business including He is also part of the Foreign Account Tax Compliance Act (FATCA) implementation team Zemer has previous experience in account monitoring and investigations Zemer spent time working directly with Caledonian’s global chief compliance officer in the Grand Cayman headquarters compliance and anti-money laundering conferences and seminars This is something he continues to do in Toronto with the latest being the 1st Annual AML & Financial Crime Conference in Toronto After having attained a Bachelor of Arts degree from Toronto’s York University Zemer went on to successfully become a Certified Anti-Money Laundering Specialist (CAMS) and is currently completing a diploma program offered by the Society of Trust and Estate Practitioners (STEP) You must be logged in to post a comment View Poll Archive ACAMS is the largest membership organization dedicated to enhancing the knowledge and skills of financial crime detection and prevention professionals worldwide. Its CAMS certification is the most widely recognized anti-money laundering certification among compliance professionals. Visit the ACAMS website at www.acams.org Join us at the Akustika Fair at the Nuremberg Exhibition Centre from April 4-6 Meet The Strad team at stand F08 and pick up a free copy of the magazine The Strad Directory Jobs Cellists Amit Peled and Ismael Guerrero perform alongside sculptures by Peled’s sister, Zemer Peled, in a programme called ‘Siblings’ Watch cellists Amit Peled and Ismael Guerrero perform ’Siblings’ - a varied programme of solo and duo cello works played alongside artwork by Peled’s sister, Zemer Peled. Filmed in Baltimore in May 2020, the programme includes: John Williams: Theme from Schindler’s List for Two Cellos Bach: Suite for Solo Cello no.4 in Eb major Boccherini: Sonata for Two Cellos in C Major, G74 Cassado: Sonata Nello Stile Antico Spagnuolo (arranged for two cellos by Peled/Guerrero) Leonard Cohen/George David Weiss: Hallelujah/What a Wonderful World (arranged by Brett Howland) Zemer Peled is an artist based in the United States, having attained an MA at the Royal College of Art in London, UK. Her art examines the beauty and brutality of the natural world, with her work formed from thousands of porcelain shards constructed into sculptures and installations of various sizes. View this post on Instagram A post shared by Zemer Peled (@zemerpeled) Read: Sentimental Work: Amit Peled Watch: John Clayton’s ‘The Hill We Climb’ performed by cellists Amit Peled and Mount Vernon Virtuosi Watch: Yo-Yo Ma performs Bloch, Bach and Song of the Birds Peled will play the instrument for a short time to promote the instrument’s sound and history with audiences describing its public debut as a ‘first date’ The violinist performs a work from his new album The Bow and The Brush which features compositions all inspired by paintings and sculptures This new arrangement by Sam Hong calls for strings and a small wind section uncovering a more intimate approach to the work Who needs the full symphony orchestra when you can play the whole thing on one violin The violinist and vocalist performs ’A Change is Gonna Come’ by Sam Cooke a song that became an anthem for the American Civil Rights Movement The mixed-instrument quartet performs a work that is quite clearly Site powered by Webvision Cloud As part of a new body of work on view at the COLLECT Art Fair which opens today in London, artist Zemer Peled (previously) created a new series of “blooming” sculptures from assorted ceramic shards The new pieces include her continued use of blue cobalt found in traditional Japanese pottery that has been smashed with a hammer and arranged in the form of large blossoms Peled also constructs much larger cactus-like pieces that can tower several feet tall or even span floor to ceiling You can see several more new blooms in her portfolio and catch her on the May cover of Ceramics Monthly Peled is represented at COLLECT by The Cynthia Corbett Gallery We have the address for the funeral home & the family on file If you're not happy with your card we'll send a replacement or refund your money The family of Mark Zemer created this Life Tributes page to make it easy to share your memories Using thousands of handcrafted porcelain shards, Israeli born artist Zemer Peled (previously) produces large-scale sculptures that are densely textured The works change depending on one’s stance at once looking as if they are made with soft feathers or sharp spines In either circumstance the pieces reflect the natural world imitating swirling wind patterns or rolling planes of grass “The forms are never static; the visual dance of sharp ceramic parts conveys a sense of constant movement,” explains Mark Moore Gallery the sculptures appear to shift shapes as you move around them an identity becoming and unbecoming in front of you.” '#' : location.hash;window._cf_chl_opt.cOgUQuery = location.search === '' && location.href.slice(0 location.href.length - window._cf_chl_opt.cOgUHash.length).indexOf('?') !== -1 '?' : location.search;if (window.history && window.history.replaceState) {var ogU = location.pathname + window._cf_chl_opt.cOgUQuery + window._cf_chl_opt.cOgUHash;history.replaceState(null "\/zemirot-shabbat-kol-mekadesh\/?__cf_chl_rt_tk=hV8V.IiLt2HtKUvGFyn5GoDGLTsI8x.cTZ6Kw489JkE-1746491706-1.0.1.1-L3w0BJBJSyGCd8WHY2kginh947GuHWAfHaHPpZjVcE8" + window._cf_chl_opt.cOgUHash);cpo.onload = function() {history.replaceState(null ogU);}}document.getElementsByTagName('head')[0].appendChild(cpo);}()); Israeli artist Zemer Peled (previously) explores both the beauty and brutality of nature with sculptures constructed from ceramic shards The pieces billow and bloom like flowers or sea creatures taking color from Peled’s use of blue cobalt found in designs and landscapes used in traditional Japanese pottery The artist uses a slab roller to build sheets of clay which are fired and then smashed to pieces with a hammer providing a contrast between smooth and soft materials that go into each piece Zemer Peled’s labor-intensive process that bridges narrative and formalist elements Peled utilizes a process of creation and destruction to make sculptures consisting of thousands of handcrafted porcelain shards resulting in works that can be read in relation to art historical tradition The sculpture’s narrative impulses lean to encounters with the otherworldly—like complex topiaries marking a not-so-distant land--yet they remain distinctly tied to earth’s patterns This conflation of the foreign and familiar creates a frenzied dislocation in the work the works spiral outwardly in rhythmic patterns interpreting not only the dynamism of nature but also the startling strangeness of a life lived in transition Peled's work examines the beauty and brutality of the natural world Her sculptural language is formed by her surrounding landscapes and nature Her sculptures and installations consist of thousands of hand-crafted porcelain shards; a technique that yields a texture both delicate and severe large scale-like ceramic pieces appear airy Peled's fragments are geometric barbs that mysteriously take on an alluring form - offering a sense of softness despite a sharp actuality She has recently been featured in Hi-Fructose Magazine and Ceramics Monthly (which featured her on the cover of the May 2015 issue) Peled transforms sharp slivers of porcelain into feathers and spines that describe objects of unknowable origins: seductive but untrustworthy The forms are complexly ordered from the inside out often bulging or spilling over with textures both delicate and severe The forms are never static; the visual dance of sharp ceramic parts conveys a sense of constant movement an identity becoming and unbecoming in front of you The act of making for Peled is a feat of endurance and adaptation with the aim to embody a fleeting but fundamental feeling of mystery The construction of her sculpture parallels negotiations any outsider makes in encountering a new world as they delicately construct a self that is both adaptable and resilient Zemer Peled’s work examines the beauty and brutality of the natural world constructed into sculptures and installations Using a slab roller Peled makes sheets of clay which are fired and then smashed into pieces with a hammer creating a contrast between soft and solid material Her current body of work inspired by the Blue and White floral and landscape designs painted on Japanese Wares Looking at the small painting then enlarging and turning them into life-size sculptures she would the viewer to feel as if they are walking inside a blue and white porcelain plate It’s time to recognize this week’s Educator of the Week presented by the Tennessee Education Lottery a first grade teacher at Caywood Elementary School in Lexington Zemer has been teaching for eleven years and says from a young age she has always had a passion for children “I’ve actually always known I wanted to be a teacher I always played school at home,” Zemer said. and also has been involved in her church helping children Her biggest challenge is getting down on herself when students aren’t understanding She says she wants to make sure she is doing her job by teaching and that the students get it. “I always like to say things and have them repeat things after me and so I think they learn best by doing and moving so I try to keep them active whenever we’re learning so that way we’re always involved,” Zemer said The best part of teaching for Zemer is the students because they make everyday fun and she enjoys coming to school to see them everyday. “I always hope my kids know that I love them but most importantly that Jesus loves them I pray every morning when I come in that I will show Jesus’ love to my students each and everyday and that they see that and that they remember that above all else,” Zemer said Zemer is now eligible for the Tennessee Education Lottery Educator of the Month award To vote for her or any other nominees, go to the Tennessee Education Lottery website To nominate an educator for our weekly award molecular biologist Zemer Gitai and his research group announced that they had discovered an antibiotic that simultaneously pierced through a disease's defenses while poisoning it from within it was not susceptible to antibiotic resistance Discovering the “poisoned arrow" required a novel combination of biochemical expertise and machine learning, which turned out to be greater than the sum of their parts, and can lead to the discovery of many more powerful medicines, said Gitai Princeton's Edwin Grant Conklin Professor of Biology and a professor of molecular biology. To that end, Gitai founded ArrePath a drug discovery spinout that recently announced a seed round of $20 million to advance its machine learning-based platform for discovering new classes of antibiotics and other drugs. “Antimicrobial resistance is one of the greatest threats of our times,” said Gitai “I am thrilled that ArrePath will help address this impending crisis by innovating the process of antibiotic drug discovery with novel technologies insightful company leadership (President and CEO Lloyd Payne and Vice President for Technology and Data Science Kurt Thorn of the Class of 1996) alumnus of Princeton who devoted his graduate school years to discovering and testing Irresistin-16 the first antibiotic identified through the ArrePath method Gitai, Martin and a team of colleagues published findings in Cell in 2020 identifying the "poisoned arrow" Irresistin-16, which can kill deadly bacteria using two independent mechanisms simultaneously who led the research team and is first author on the new article about the ‘poisoned arrow’ antibiotic “We used a computational machine learning approach with Irresistin and our idea here is that we can use similar types of approaches to very quickly identify other novel drugs,” said Gitai “A key thing at the heart of our thinking is: What are the strengths of working with bacteria in the antibiotic space the big advantage comes from bacteria’s short lifespan The studies are very fast and cheap and scalable and quantitative so we can generate a ton of data super quickly — and that's vitally important because data is the fodder for machine learning.” Irresistin-16 is a proof of concept for ArrePath's new method of developing future antibiotics “Princeton is tremendously excited at the launch of ArrePath,” said Tony Williams, new ventures associate in Princeton’s Office of Technology Licensing in combination with the experienced and capable management team provides the perfect platform for the company to further develop Professor Gitai’s important technology and discover next-generation anti-infective therapeutics ArrePath is the latest in a growing portfolio of high potential well-resourced companies that have emerged out of Princeton research in recent years." Gitai serves as the chair of the company’s science advisory board. Barbara E. Englehardt, professor of computational biology in the Department of Computer Science at Princeton also serves on ArrePath’s scientific advisory board, and Gary Laevsky director of Princeton’s Confocal Imaging Facility The research was supported primarily by the National Institutes of Health (DP1AI124669 to ZG JKM) with additional funding from the National Science Foundation (NSF PHY-1734030) Flow cytometry was performed at the Princeton University Flow Cytometry Resource Facility supported by the National Cancer Institute (NCI-CCSG P30CA072720-5921) Israeli ceramicist Zemer Peled took up pottery as part of therapy after a break-up in her 20s and now exhibits her work at galleries and museums around the world Zemer’s large and small-scale sculptures and installations examine the beauty and brutality of the natural world and are made from thousands of porcelain shards that she creates using her growing collection of hammers Zemer found herself getting overwhelmed and used her ‘lifesaver’ – clay – to help her process what was going on around her Video produced by Caitlin Sneddon.Programme produced by Jane Thurlow This website is using a security service to protect itself from online attacks The action you just performed triggered the security solution There are several actions that could trigger this block including submitting a certain word or phrase You can email the site owner to let them know you were blocked Please include what you were doing when this page came up and the Cloudflare Ray ID found at the bottom of this page Artist Zemer Peled creates something whole from things that are broken Her ceramic sculptures of plant-like organisms are formed with thousands of porcelain shards The arrangements are a spellbinding combination of colors and forms that have an otherworldly appeal conveys this sort of beguiling beauty; the pieces have an inviting warmth to them with tropical greens their texture is defensive with porcupine line-like needles that cover their entire surfaces The nature of Peled’s work is often at odds with one another. “The association of porcelain with grace, refinement, and civilization is turned on itself when we are confronted with this material in another state,” she says there’s a “brutality” to her work with its all-over fragmentation “When seen in the organic formations of Peled’s structures this time estranged from its original context of neatness but nonetheless unified by an overall cohesiveness of movement and composition.” Scroll down to enjoy the details of In Eden. Then, follow Peled on Instagram to see what she’s working on next A post shared by Zemer Peled (@zemerpeled) Zemer Peled: Website | Facebook | Instagram Surreal Ceramic Sculptures Expertly Crafted to Look Like Carved Wood Artist Fuses Ceramics Plates With Fringe To Explore Her Dual Heritage as a Mexican-American Colossal Ceramic Installation Reflects the Fragility of the Coral Reef Want to advertise with us? Visit My Modern Met Media Celebrating creativity and promoting a positive culture by spotlighting the best sides of humanity—from the lighthearted and fun to the thought-provoking and enlightening '+n.escapeExpression("function"==typeof(o=null!=(o=r(e,"eyebrowText")||(null!=l?r(l,"eyebrowText"):l))?o:n.hooks.helperMissing)?o.call(null!=l?l:n.nullContext||{},{name:"eyebrowText",hash:{},data:t,loc:{start:{line:28,column:63},end:{line:28,column:78}}}):o)+" \n '+(null!=(o=c(e,"if").call(r,null!=l?c(l,"cta2PreText"):l,{name:"if",hash:{},fn:n.program(32,t,0),inverse:n.noop,data:t,loc:{start:{line:63,column:20},end:{line:63,column:61}}}))?o:"")+"\n"+(null!=(o=(c(e,"ifAll")||l&&c(l,"ifAll")||n.hooks.helperMissing).call(r,null!=l?c(l,"cta2Text"):l,null!=l?c(l,"cta2Link"):l,{name:"ifAll",hash:{},fn:n.program(34,t,0),inverse:n.noop,data:t,loc:{start:{line:64,column:20},end:{line:70,column:30}}}))?o:"")+" Princeton faculty members Coleen Murphy, Mohamed Abou Donia and Zemer Gitai are among 20 researchers nationwide to receive 2021 Transformative Research Awards from the National Institutes of Health (NIH) Murphy is also one of the 10 recipients of the NIH Director's Pioneer Award — the only recipient of both the Pioneer Award and the Transformative Research Award this year. These awards are part of the NIH Common Fund’s High-Risk, High-Reward Research Program which supports investigators pursuing highly innovative high-impact biomedical and behavioral research Murphy, professor of molecular biology and the Lewis-Sigler Institute for Integrative Genomics, received the Pioneer Award for her project, "Cracking the code of transgenerational inheritance of behavior." Murphy graduated from the University of Houston with a B.S earned her doctorate in Biochemistry at Stanford University then did her postdoctoral work at UCSF with Cynthia Kenyon including cognitive aging and reproductive aging which has enabled them to identify remarkably well-conserved genetic pathways that can extend each of these processes with age Murphy’s team made the surprising discoveries that C elegans can “read” the small RNAs that bacteria produce and use the information to avoid pathogens and transmit this learned information both vertically (transgenerationally) and horizontally (to neighboring animals) These results have opened up new avenues of research into memory transfer transgenerational inheritance and small-RNA-mediated trans-kingdom communication Murphy, Abou Donia and Gitai each received the Transformative Research Award for their shared project, "Small RNAs as Novel Modulators of Microbe-Host Interactions." Abou Donia an associate professor of molecular biology After completing his post-doctoral studies at the University of California-San Francisco Donia started his independent laboratory in 2014 at Princeton his group investigates the role of the human microbiome in health disease and response to therapeutic interventions He is a recipient of the NIH Director's New Innovator Award the Kenneth Rainin Foundation Innovation and Breakthrough Awards the Pershing Square Sohn Prize for Young Investigators in Cancer Research the Vilcek Prize for Creative Promise in Biomedical Science and has been named a Pew Biomedical Scholar Gitai Princeton's Edwin Grant Conklin Professor of Biology received his bachelor's degree from MIT in 1996 and his doctorate from UCSF in 2002 After his postdoctoral work with Lucy Shapiro at Stanford University he joined the faculty of Princeton University in 2005 His research focuses on the cell biology of bacteria studying how cells self-organize across spatial scales molecular and engineering approaches to understand to understand problems such as cell shape formation metabolic organization and community structure the Gitai lab has extended its use of quantitative methods to discover novel features of microbe-host interactions and antibiotics with novel mechanisms of action Gitai's achievements have been recognized by many prestigious awards including the NIH Director's Pioneer Award the NIH New Innovator Award and the Beckman Young Investigator Award Email: editor@tiranatimes.com “Maldives Vibes” towers at 72 x 36 x 36 inches and assumes the form of coral reefs found underwater “In Eden,” a collection of six corals in green “Intertwine,” towers at 21 x 16 x 21 inches and takes the form of intertwined the grandiose “Coronavirus 1” and “Coronavirus 2” sold for a whopping $2,600 and $4,800 Read the commentsFiled in:art Decor & Accessories Design The home you love starts here The home you love starts here Apartment TherapyThe wordmark for the Apartment Therapy brand.More From Us By subscribing, you acknowledge and agree to our Terms of Use and Privacy Policy. A team of Princeton researchers led by Professor Zemer Gitai has found an antibiotic that can simultaneously puncture bacterial walls and destroy folate within their cells — taking out even monstrous bacteria with the effectiveness of a poisoned arrow — while proving immune to antibiotic resistance Poison is lethal all on its own — as are arrows — but their combination is greater than the sum of their parts A weapon that simultaneously attacks from within and without can take down even the strongest opponents coli to MRSA (methicillin resistant Staphylococcus aureus) A team of Princeton researchers reported today in the journal Cell that they have found a compound that can simultaneously puncture bacterial walls and destroy folate within their cells — while being immune to antibiotic resistance Bacterial infections come in two flavors — Gram-positive and Gram-negative — named for the scientist who discovered how to distinguish them The key difference is that Gram-negative bacteria are armored with an outer layer that shrugs off most antibiotics no new classes of Gram-negative-killing drugs have come to market in nearly 30 years “This is the first antibiotic that can target Gram-positives and Gram-negatives without resistance,” said Zemer Gitai, Princeton’s Edwin Grant Conklin Professor of Biology and the senior author on the paper But what we’re most excited about as scientists is something we’ve discovered about how this antibiotic works — attacking via two different mechanisms within one molecule — that we are hoping is generalizable leading to better antibiotics — and new types of antibiotics — in the future.” The greatest weakness of antibiotics is that bacteria evolve quickly to resist them but the Princeton team found that even with extraordinary effort they were unable to generate any resistance to this compound which is why we call the compound’s derivatives ‘Irresistin,’” Gitai said It’s the holy grail of antibiotics research: an antibiotic that is effective against diseases and immune to resistance while being safe in humans (unlike rubbing alcohol or bleach which are irresistibly fatal to human cells and bacterial cells alike) this is like discovering the formula to convert lead to gold or riding a unicorn — something everyone wants but no one really believes exists graduate who spent most of his graduate career working on this compound “My first challenge was convincing the lab that it was true,” he said But irresistibility is a double-edged sword Typical antibiotics research involves finding a molecule that can kill bacteria breeding multiple generations until the bacteria evolve resistance to it looking at how exactly that resistance operates and using that to reverse-engineer how the molecule works in the first place the researchers had nothing to reverse engineer from “This was a real technical feat,” said Gitai “No resistance is a plus from the usage side but a challenge from the scientific side.” The research team had two huge technical challenges: Trying to prove the negative — that nothing can resist SCH-79797 — and then figuring out how the compound works Martin tried endless different assays and methods none of which revealed a particle of resistance to the SCH compound meaning that he exposed bacteria to the drug over and over and over again Since bacteria take about 20 minutes per generation the germs had millions of chances to evolve resistance — but they didn’t the team also serially passaged other antibiotics (novobiocin nisin and gentamicin) and quickly bred resistance to them Proving a negative is technically impossible so the researchers use phrases like “undetectably-low resistance frequencies” and “no detectable resistance,” but the upshot is that SCH-79797 is irresistible — hence the name they gave to its derivative compounds They also tried using it against bacterial species that are known for their antibiotic resistance, including Neisseria gonorrhoeae, which is on the top 5 list of urgent threats published by the Center for Disease Control and Prevention “Gonorrhea poses a huge problem with respect to multidrug resistance,” said Gitai I was given penicillin-G — the penicillin discovered in 1928 the standard strains that are circulating on college campuses are super drug resistant the break-glass-in-case-of-emergency drug for Neisseria and there really is no break-glass backup anymore That’s why this one is a particularly important and exciting one that we could cure.” The researchers even got a sample of the most resistant strain of N gonorrhoeae from the vaults of the World Health Organization — a strain that is resistant to every known antibiotic — and “Joe showed that our guy still killed this strain,” Gitai said a co-first-author on the paper and the lab manager for the Gitai Lab Without resistance to reverse engineer from the researchers spent years trying to determine how the molecule kills bacteria from classical techniques that have been around since the discovery of penicillin through to cutting-edge technology Martin called it the “everything but the kitchen sink” approach and it eventually revealed that SCH-79797 uses two distinct mechanisms within one molecule Princeton authors on the paper include Joseph Sheehan (left) seen here on a pre-social-distancing walk across the Princeton campus “The arrow has to be sharp to get the poison in, but the poison has to kill on its own, too,” said Benjamin Bratton, an associate research scholar in molecular biology and a lecturer in the Lewis Sigler Institute for Integrative Genomics The arrow targets the outer membrane — piercing through even the thick armor of Gram-negative bacteria — while the poison shreds folate a fundamental building block of RNA and DNA The researchers were surprised to discover that the two mechanisms operate synergistically combining into more than a sum of their parts “If you just take those two halves — there are commercially available drugs that can attack either of those two pathways — and you just dump them into the same pot that doesn’t kill as effectively as our molecule which has them joined together on the same body,” Bratton said There was one problem: The original SCH-79797 killed human cells and bacterial cells at roughly similar levels it ran the risk of killing the patient before it killed the infection It is nearly 1,000 times more potent against bacteria than human cells the researchers demonstrated that they could use Irresistin-16 to cure mice infected with N This poisoned arrow paradigm could revolutionize antibiotic development, said KC Huang a professor of bioengineering and of microbiology and immunology at Stanford University who was not involved in this research “The thing that can’t be overstated is that antibiotic research has stalled over a period of many decades,” Huang said “It’s rare to find a scientific field which is so well studied and yet so in need of a jolt of new energy.” the synergy between two mechanisms of attacking bacteria who was a postdoctoral researcher at Princeton from 2004 to 2008 “This compound is already so useful by itself people can start designing new compounds that are inspired by this That’s what has made this work so exciting.” each of the two mechanisms — the arrow and the poison — target processes that are present in both bacteria and in mammalian cells Folate is vital to mammals (which is why pregnant women are told to take folic acid) and of course both bacteria and mammalian cells have membranes because there’s a whole class of targets that people have largely neglected because they thought because then I would just kill the human as well,’” Gitai said “A study like this says that we can go back and revisit what we thought were the limitations on our development of new antibiotics,” Huang said it’s fantastic to have new hope for the future.” “A dual-mechanism antibiotic kills Gram-negative bacteria and avoids drug resistance,” by James K appears in the June 25 issue of the journal Cell and was released online on June 3 (DOI: 10.1016/j.cell.2020.05.005) Gabby Zemer was also hired as a new executive Sony Pictures has renewed its first-look deal with Will Gluck’s Olive Bridge Entertainment announced the hire of Gabby Zemer as a new executive at the company Zemer spent the past three years at Blumhouse Productions where she worked alongside Couper Samuelson on the upcoming “Black Christmas” remake Zemer worked under Deborah Jelin Newmyer at Outlaw Productions shortly after graduating from NYU Tisch School of the Arts Gluck’s long history at the studio includes the smash hit Emma Stone comedy “Easy A” ($75 million worldwide) “Friends with Benefits” ($150 million worldwide) the musical “Annie” ($134 million worldwide) and the worldwide animated blockbuster “Peter Rabbit” ($351 million worldwide) It became Sony Pictures’ highest-grossing film ever in the U.K. Gluck is currently in post-production on “Peter Rabbit 2: The Runaway,” which will be released in theaters worldwide on April 3 Olive Bridge has several films in development at the studio including “Steal Away,” a remake of the French romantic comedy heist “The Last Diamond,” written by Gluck and Chris Bremner and “Move On,” a sci-fi romance spec script by Ken Kobayashi (repped at UTA and Gotham Group) Gluck and the studio also announced two new projects in development: An ensemble comedy inspired by the worldwide videogame phenomenon “Just Dance” from Ubisoft with a screenplay written by Amelie Gillette Brian Gatewood & Alessandro Tanaka for Screen Gems; “Much Ado,” a modern retelling of Shakespeare’s “Much Ado About Nothing,” a pitch from Ashley Bradley (repped by Gersh); an English-language adaptation of the bestselling Japanese book and hit film from Toho “If Cats Disappeared from the World,” which Olive Bridge is producing with Masi Oka Gluck’s television business is with eOne under a two-year overall deal and includes “Encore” on Disney+ and an animated series in production at Netflix Olive Bridge is repped by UTA and Sloan Offer Using thousands of ceramic shards Israeli artist Zemer Peled constructs sculptures that resemble beautiful blooming flowers The intricate works combine a variety of colors and designs most notably cobalt blue that's used in traditional Japanese pottery Peled arranges the shards according to their length The similar-looking pieces form long petals with a dotted Peled uses a slab roller and creates sheets of clay that are glazed and fired She then smashes them into small pieces using a hammer These shards are later divided and collaged into her sculptures Peled's work engages both the beauty and brutality of nature through appearance and touch her ceramics highlight the elegance of flowers and their incredible organic structure pointed edges and are a stark contrast to the soft-colored blooms Want to advertise with us? Visit My Modern Met Media. Celebrating creativity and promoting a positive culture by spotlighting the best sides of humanity—from the lighthearted and fun to the thought-provoking and enlightening. Show Search Search Query Submit Search Don't Miss Print Yom Kippur is a complicated day for Miriam Bar-Zemer which begins this year on the evening of Sept is considered the holiest day of the year — a time of deep introspection which Jews have traditionally honored by spending the day in synagogue in a collective act of prayer a 29-year-old graduate student who was born in Israel and grew up fairly secular in Los Angeles deciding what to do on that day is an annual challenge Her family didn’t belong to a synagogue for most of her childhood and now as an adult it’s not a space that she finds conducive to self-reflection but she feels like fasting in isolation misses the point “I feel like it being the most important holiday but then I struggle to meld the tradition with my own interpretation of what it means to feel redemption,” she said Lifestyle A death meditation may sound morbid, but often it’s a celebration of life. At a Pasadena shop, you can experience a moving death meditation for yourself. Even for many non-religious Jews, Yom Kippur addresses a fundamental need, said Rabbi Tarlan Rabizadeh, vice president for Jewish engagement at American Jewish University. “We’ve got this one day to really wrestle and go deep,” she said. “It’s like it’s in our DNA.” “We find lots of ways to hide from our brokenness during the year,” said Rabbi Joel Nickerson of Wilshire Boulevard Temple. “This is the one day to focus on your brokenness, and you’re supposed to do it in the presence of other people. It’s a double layer of vulnerability.” Despite all this painful soul-searching, most rabbis will tell you that Yom Kippur is a hopeful holiday, designed to help individuals examine, reckon with and take action to shed their guilt and shame. “A lot of people see it as a day they are supposed to not eat and sit in services that are boring,” Nickerson said. “That’s on us as religious leaders to make the services more relevant and meaningful to people’s lives.” In another departure from tradition, Nickerson plans to lead a “paddleboard and prayer” service on Sunday to celebrate Rosh Hashana, the Jewish new year that begins 10 days before Yom Kippur. “We meet in Malibu, go into the ocean and circle up and do a service out there,” he said. “You can’t just rely on people showing up for the traditional experiences.” Find yourself at these Los Angeles-area labyrinths when you’re feeling overwhelmed — or when you just want a calming, off-the-beaten path experience. Kaplan has fasted on Yom Kippur in the past but stopped years ago after she sat next to a young undergraduate student at services who grew faint from not eating. “I took him home with me and made lunch for both of us,” she said. “It felt more important to feed him than to fast, and that was my last experience with fasting.” Now Kaplan spends Yom Kippur and the days before it (known in the Jewish tradition as the Yamim Noraim or the Days of Awe) making a deliberate effort to reach out to friends and family with whom she has not been in regular contact. “Especially at that time, I think about the people who are important to me,” she said. “And at this point in life, getting on as one is, it becomes more important to talk to people because you don’t know how they are doing.” For Dani Mahrer, 36, creating space for self-reflection on Yom Kippur means climbing a mountain on her own. Last year, the South Pasadena resident took the day of Yom Kippur off work and drove up Angeles Crest Highway for an eight-mile hike up Mt. Baden-Powell. “I didn’t want to fast and I didn’t want to go to synagogue, but I wanted to do something meaningful,” she said. “I find I can be the most self-reflective and focused and not distracted when I’m out in nature and where I don’t have cell service.” California These 12 beautiful places in Los Angeles will lift your spirits who lives in Brentwood and identifies as “proudly Jewish” and atheist describes the holiday as having a weight around it that is felt by both religious and nonreligious Jews “Even if you don’t think about your Jewish identity for 364 days a year if you forgot it was Yom Kippur and then you find out Over the past two years he has honored the holiday by speaking at synagogues about his work as community engagement director for the Western region of HIAS a Jewish nonprofit that resettles refugees “My office is officially closed on Yom Kippur but if there is an opportunity to bring more people into the work I’m doing I want to take it,” he said “I find that experience really meaningful.” He doesn’t fast — “I don’t find it helps me be a better healthy person” — but he always attends his family’s large meal to break the fast at the end of the day “There’s something really joyous about it,” he said Cantor Jonathan Friedmann, the community leader of Adat Chavarim, a small humanistic community that emphasizes Jewish culture rather than the theistic religion, said the group holds one service to cover both Rosh Hashanah and Yom Kippur. “We take the high notes from both of the holidays, filter it through a humanistic lens, and give it to the people in about an hour,” he said. “It’s rather informal and also meaningful.” The community deliberately leaves the day of Yom Kippur open to allow congregants to choose how to honor it in a way that feels authentic to each individual. Some feel like they already acknowledged the High Holidays and treat Yom Kippur as just another day, while others might join family for more conventional services. Still others, like Friedmann, who also works as a dean at the Academy for Jewish Religion, California, take the day off from work and commemorate the holiday in the same way the average American might celebrate Memorial Day or July Fourth — as a day to pause, reflect and be grateful for the break from daily life. “For Jews who are keyed into their culture, I think Yom Kippur and Rosh Hashanah play that role,” he said. “These are important days that you shouldn’t treat like other days, but that doesn’t mean you have to go to synagogue.” Sound baths are everywhere in Los Angeles, even in churches. Here’s what it’s like to experience the singing bowls and gongs in grand, acoustic settings. Rabbi Noah Farkas, president and CEO of the Jewish Federation of Greater Los Angeles, said he’s not surprised that roughly half of the Jewish adults in Los Angeles choose to spend Yom Kippur outside of synagogue. After all, the city is filled with creative thinkers and abundant, awe-inspiring beauty. “Some don’t care at all, but the other 49% are up in the mountains, they are riding bikes on the beach, they are meditating on the waves or meeting with friends to come up with creative rituals on how to let go of what is holding them down,” he said. “All those things are exploding all at once.” Farkas said the traditional Yom Kippur practices of not eating, sitting in synagogue, covering one’s head with the prayer shawl and abstaining from the “delights of the world” help him get into a space of self-reflection, but he understands that doesn’t work for everyone. “If that’s not the right technology for you, then go find the thing that gets you into that place,” he said. “And if you’re a creative person, make the thing.” As for Bar-Zemer. she still doesn’t know how she’ll spend Yom Kippur this year, but she appreciates that there are a variety of options available to her. “The beauty of Judaism to me is there is so much diversity,” she said. Deborah Netburn covers faith, spirituality and joy for the Los Angeles Times. She started at The Times in 2006 and has worked across a wide range of sections including entertainment, home and garden, national news, technology and science. Subscribe for unlimited access Site Map A team of Princeton researchers has identified a compound that can kill both Gram-positive and Gram-negative bacteria via two independent mechanisms works by simultaneously targeting bacterial folate metabolism and membrane integrity SCH-79797 was found to be more effective than a combination of existing treatments against methicillin-resistant Staphylococcus aureus was also found to be effective against Neisseria gonorrhoeae in a mouse vaginal infection model Pathogenic bacteria can be classified as either Gram-positive or Gram-negative who developed a staining technique that can distinguish between them The key difference is that Gram-negative bacteria are protected by an outer layer that resists most antibiotics no new classes of Gram negative-killing drugs have come to market in nearly 30 years “ … only six new classes of antibiotics have been approved in the past 20 years none of which are active against Gram-negative bacteria,” the authors wrote And despite recent efforts to “reinvigorate antibiotics research,” they continued most of this work has resulted in compounds that function via similar mechanisms to those of traditional antibiotics while recently discovered natural product-derived candidates have either only been effective against Gram-positive bacteria there is still a strong need for characterizing new classes of antibiotics with distinct mechanisms of action (MoA) especially those that target Gram-negatives with low resistance frequency,” the team noted “An ideal antibiotic would be hard to develop resistance against able to kill both Gram-positive and Gram-negative bacteria and easy to access.” The holy grail of antibiotics research would thus be an antibiotic that is effective against the pathogen A team of Princeton researchers led by Zemer Gitai have found an antibiotic that can simultaneously puncture bacterial walls and destroy folate within their cells—taking out even monstrous bacteria with the effectiveness of a poisoned arrow—while proving immune to antibiotic resistance Authors on the new paper in Cell include Joseph Sheehan (left) [Courtesy of Zemer Gitai]The Princeton University team identified the new candidate as one of the most potent “hits” in a small molecule library screen the compound had previously been reported as a human PAR-1 antagonist Another study had suggested that SCH-79797 increased the ability of neutrophils to kill bacteria perhaps by directly functioning as an antibiotic Studies focusing on its anticoagulant activity had also suggested that SCH-79797 could be safely tolerated in animals so the Princeton researchers carried out further studies to further investigate its antibiotic properties Bacteria are adept at evolving quickly to resist antibiotics but the researchers found that they were unable to generate any resistance to SCH-79797 or riding a unicorn—something everyone wants but no one really believes exists “My first challenge was convincing the lab that it was true.” The ability of a compound to resist the development of bacterial resistance is also something of a double-edged sword going through multiple generations of bacteria until they evolve resistance to it But since SCH-79797 was proving irresistible “This was a real technical feat,” said Gitai “No resistance is a plus from the usage side but a challenge from the scientific side.” This gave the research team the challenge of both trying to prove that bacteria wouldn’t develop resistance to SCH-79797 To demonstrate that bacteria would not become resistant to the compound Martin first tried a multitude of different assays and methods none of which revealed the development of any resistance whatsoever He then carried out serial passaging over 25 days which involved exposing the bacteria to the drug over repeated generations Bacteria take about 20 minutes per generation so while this duration of serial passaging gave them millions of chances to evolve resistance the scientists also serially passaged other antibiotics (novobiocin and gentamicin) and showed that bacteria quickly developed resistance to them “… mutants that evolved increased resistance to antibiotics like trimethoprim and nisin did not demonstrate cross-resistance to SCH-79797,” the team noted This apparent “irresistable” characteristic of SCH-79797 was the basis for naming derivative compounds which is why we call the compound’s derivatives ‘Irresistin,'” Gitai said The team also tested the compound against bacterial species that are known for their antibiotic resistance which is on the top five list of urgent threats published by the Center for Disease Control and Prevention “Gonorrhea poses a huge problem with respect to multidrug resistance,” said Gitai “We’ve run out of drugs for gonorrhea I was given penicillin-G—the penicillin discovered in 1928 That’s why this one is a particularly important and exciting one that we could cure.” The researchers acquired from the World Health Organization repository a sample of the most resistant strain of N which is resistant to every known antibiotic and “Joe showed that our guy still killed this strain,” Gitai said “We’re pretty excited about that.” from classical approaches that have been around since the discovery of penicillin Martin called it the “everything but the kitchen sink” approach The team likened this to using an arrow coated in poison “The arrow has to be sharp to get the poison in an associate research scholar in molecular biology and a lecturer in the Lewis Sigler Institute for Integrative Genomics The arrow targets the outer bacterial membrane piercing through even the protective coat of Gram-negative bacteria “… the combination of two different antibacterial activities on the same molecular scaffold can produce a more potent antibacterial effect than co-treating with two antibiotics with the two separate targeting activities,” the investigators wrote “If you just take those two halves—there are commercially available drugs that can attack either of those two pathways—and you just dump them into the same pot that doesn’t kill as effectively as our molecule which has them joined together on the same body.” One problem with SCH-79797 was that it killed human cells and bacterial cells at roughly similar levels so the researchers developed an SCH-79797 derivative that they demonstrated was nearly 1,000 times more potent against bacteria than human cells the researchers demonstrated that they could use Irresistin-16 to cure mice infected with N This poisoned arrow paradigm could revolutionize antibiotic development a professor of bioengineering and of microbiology and immunology at Stanford University who was not involved in the research “The thing that can’t be overstated is that antibiotic research has stalled over a period of many decades,” Huang said “It’s rare to find a scientific field which is so well studied and yet so in need of a jolt of new energy.” The synergy between two mechanisms of attacking bacteria “can provide exactly that,” added Huang who was previously a postdoctoral researcher at Princeton “This compound is already so useful by itself That’s what has made this work so exciting.” Each of the two mechanisms targeted by the new compounds are present in both bacteria and in mammalian cells and both bacteria and mammalian cells have membranes because there’s a whole class of targets that people have largely neglected because they thought because then I would just kill the human as well,'” Gitai said that are effective in animals and address these key criteria with a unique dual-targeting MoA the ability to kill both Gram-negative and Gram-positive pathogens and an undetectably low frequency of resistance,” the authors concluded “The acute need for new antibiotics to treat N gonorrhoeae makes IRS-16 particularly promising small molecule candidate for future development … This promising antibiotic lead suggests that combining multiple MoAs onto a single chemical scaffold may be an underappreciated approach to targeting challenging bacterial pathogens … Thus our findings identify and characterize a promising new antibiotic and provide a potential roadmap for future antibiotic discovery efforts.” “A study like this says that we can go back and revisit what we thought were the limitations on our development of new antibiotics,” Huang further commented it’s fantastic to have new hope for the future.” Copyright © 2025 Sage Publications or its affiliates including those for text and data mining and training of large language models .st1{fill-rule:evenodd;clip-rule:evenodd;fill:#2a2a2a}By Jon Szerlag | jszerlag@mlive.com ZEMER (TREMBLAY), MARYLYN ANNE Michigan Center Michigan Born December 21st 1931 in Jackson Preceded in death by her husband of 57 years Norman R She retired from the State of Michigan after 33 years of service as an Administrative Manager She enjoyed going to Texas during the winter and being with her family She was a member of Our Lady of Fatima Parish for 50 years where she played the organ for 13 years and worked with the school children and also worked with the funeral dinner gang She also played the organ for Sacred Heart Catholic Church of Hudson MI Marylyn belonged to the Friends of the Jackson County Library she belonged to the Holy Family Catholic Parish of Lindale where she played the organ sang in the choir and worked the soup kitchen She and several friends also worked the Catholic Thrift Store View Marylyn Anne Zemer's full obituary. Visit Marylyn Anne Zemer's guestbook. Visit the Jackson Citizen Patriot obituary page. See more obituaries from the Jackson Citizen Patriot: Use of and/or registration on any portion of this site constitutes acceptance of our User Agreement, (updated 8/1/2024) and acknowledgement of our Privacy Policy, and Your Privacy Choices and Rights (updated 1/1/2025) © 2025 Advance Local Media LLC. 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