When US-born Altamura Distilleries managing director Frank Grillo was choosing where to move in Italy he had three top priorities: somewhere south Renowned for their hearty and flavorfully complex Pane di Altamura—not to mention the region’s three surrounding airports—Puglia quickly became the obvious option Grillo began to understand the joys of the region far beyond its locational and gastronomic advantages—the hospitality of the region combined with its peoples' joie de vivre Grillo saw the region's PDO certified bread as an opportunity to create something truly unique and celebratory of the region Its complex grains already provided for an impressive base for the region’s coveted loaves but what if someone could tap even further into their potential Triple distilled and five times filtered through active charcoal the goal with the spirit’s unique taste was to let people experience Altamura in liquid form As rich in flavor as it is smooth going down the vodka offers a taste of the region in a bold and new a world made of people who love to share and live their lives fully,” says Grillo this vodka represents a new and undiscovered tasting experience." The multi-award winning distillery’s newest release can be found on shelves in Italy Grillo sat down to share more details about Altamura's past ‍Italy is synonymous with wine and olive oil What challenges did you face introducing vodka into such a wine-dominant culture You are absolutely correct about the prevalence of wine and low alcohol beverage consumption Our approach in Italy has been to focus on the provenance of the product and its linkage to the history of Pane di Altamura and its wheat Italy is a country that celebrates its regional heritage and the food and wine that have been a part of that heritage for literally centuries We have aligned Altamura vodka as another way of experiencing the culinary history that is so deeply linked to its namesake bread and city ‍What was the reaction of local Pugliese communities when they learned you were transforming their beloved wheat into vodka and fascination were the initial reactions we met It has evolved into deep appreciation and pride that we are taking this important Pugliese food source and expressing it in a way that is both innovative ‍Altamura Vodka celebrates Pugliese terroir in liquid form If you could describe its flavor profile as a personality that dinner guest who doesn't talk too much ‍Pane di Altamura is a staple at every table in Puglia How does Altamura Vodka pair with traditional Pugliese dishes We love to serve our Altamura Martini (three parts vodka with one part excellent dry vermouth such as Carpano garnished with a twist) alongside Pane di Altamura dipped in some amazing Pugliese Olive oil ‍How has being an American in Italy influenced your approach to crafting and marketing an authentically Italian product I think we brought a fresh view to the story of Altamura Innovation does not need to mean destroying or ignoring the past I think we understood the history of Altamura and how the specific wheat raised in a unique terroir came to produce outstanding bread We just asked what other story the wheat could tell ‍If you could share a glass of Altamura Vodka with anyone — past or present — who would it be It has to be Fellini and I would toast to his mantra "La vita è una combinazione di pasta e magia" ‍What’s on the horizon for Altamura Distilleries or is there a new chapter brewing in your portfolio But we definitely want to explore other ways to express the wheat and terror of Altamura We're starting to plan for American-style wheated whiskeys Stay up-to-date with exclusive events and content Thousands in Centre County Lose Power After Severe Storms Man Dies by Electrocution in State College After Severe Storm Damaged Power Lines Road Closures Continue in Centre County After Severe Storm Marie-Louise Altamura passed away January 16 2025 at age 100 at Centre Care in Bellefonte Marie-Louise was preceded in death by her brother Jacques Derasse who passed away Oct. Her father served in the French Foreign Legion in Africa and Indo China and died when she was seven years old in 1931 Due to her mother’s poor health she lived with her Aunt & Uncle in Coligny where she attended boarding school Marie-Louise lived in Algeria for one year with her Aunt & Uncle where she attended College of Maison Carree in the town of Maison Carree She returned to Paris the following year when she received word that Germany was preparing to invade Paris She was part of the Exodus and witnessed the Germans marching into Paris She shared stories of how the Parisians suffered many hardships during the war During this time she lived with her Aunt & Uncle Camille who was Chief of the French Resistance where she witnessed American soldiers secretly sleeping in their home At the end of the war she was present with her mother when her Uncle Camille was arrested by the Germans and taken to prison. At the end of the war Marie-Louise met an American soldier in Chalons sur Marne in 1946 and came to the U.S 1946 where they were married in NYC and settled in Norwich Marie-Louise taught French in two private girls’ schools in MD and retired from St CT in 1986 where she taught French 1,2,3,4 & 5 She loved her students and teaching them the French language as well as taking some of her students to France and various countries every other year. PA and leaves behind 7 grandchildren and 17 great grandchildren She had a great sense of humor and she loved hearing stories about her grandchildren & great grandchildren and was known as Grandmere A funeral service will be held at Koch’s Funeral Home in State College on Sat. She will be buried at Graysville Cemetery in Spruce Creek 80% of consumers turn to directories with reviews to find a local business We offer the latest breaking news and videos straight from the Centre County region in Central PA Contact us: info@statecollege.com © Copyright 2000 – 2024 | StateCollege.com® | All Rights Reserved | State College PA – Centre County – Central Pennsylvania – Home of Penn State University This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply. StateCollege.com Privacy Policy page This Valentine’s Day, luxury Mayfair hotel The Ritz London introduces the Aurora Rubra, a sun-kissed cocktail celebrating the romance and vibrancy of Southern Italy. Exclusively available throughout February, the Aurora Rubra is inspired by two quintessential elements of Italian terroir—premium vodka from Puglia and succulent blood oranges from Sicily. Deep crimson in colour, thanks to luscious blood orange juice, the Aurora Rubra evokes fiery sunrises over Mount Etna, while its sweet-tart flavour delivers vibrant complexity. Italian vermouth, Mancino Sakura, adds herbal and floral notes, celebrating Italy’s rich traditions. A touch of Japanese sake brings balance and elegance with its smooth, umami-rich character, while a splash of Spanish sherry nods to the shared Mediterranean heritage with nutty depth and subtle salinity. Conceived to whisk guests away to the sun-soaked Mediterranean, the Aurora Rubra—meaning “Red Dawn”—offers a deliciously sophisticated mix of flavours, perfect for intimate, low-lit celebrations at The Ritz this Valentine’s season. Aurora Rubra: A Sun-Kissed Toast to Southern Italy Ross is one of the co-founders of The Luxury Editor. Fight manager Altamura, one of the most-knowledgeable, passionate and interesting figures in the sport, is in the north of England with Doheny as they prepare for Saturday’s fight with Liverpool’s aggressive WBA featherweight champion Nick Ball. Doheny has seen almost everything, fighting almost everywhere. He’s been favorite and underdog, written off and hyped up. “I think he’s one of those fighters that not many would have actually predicted to win a world championship on the way up, even though he's always a quality operator and he was an elite amateur,” says Altamura. Now a worldy-wise veteran who has fought Nayoa Inoue, Michael Conlan, Iount Baluta, Daniel Roman, and Sam Goodman, Doheny’s boxed in Ireland, Australia, Japan, Dubai, the US, and Thailand. When they travelled back to Japan last May – to box in the Tokyo Dome in Doheny’s fourth fight in Japan – he did so knowing that victory could see him box Naoya Inoue in his next fight. That proved to be the case, too, and he fought modern great Inoue last September inside the Ariake Arena. Having given a good account of himself, and given Inoue more to think about than many believed he would, Doheny suffered a back spasm that caused him issues for days afterwards. Despite the pain, the veteran knew he had more left to give the sport before he even left the dressing room that night. “Straight away,” says Altamura. “In the dressing room, straight away, he said to me that he wanted to press on if there was the right opportunities.” Doheny wasn’t satisfied with the ending, but he was vindicated by his performance. Some had anticipated he would be blown away, but he was competitive, claimed a round or two and then his back awkwardly seized up. Altamura views Ball as a clever fighter, a crafty champion who knows how to use his diminutive stature but squat, physical presence. He feints well, has a solid jab, and tries to break his opponents down. The skilful Doheny will have to offset any momentum Ball can build, keep him turning, adjust his feet and do his best to at least contain the champion if not shut him down entirely. “I think the belief that I take is that if he [Ball] wants to go rushing through the front door, he’s gonna to find out,” Altamura adds. “I think that TJ is the best puncher he’s been in with so far. TJ is a very explosive puncher. So if he wants to come rushing through the door and trying to bully and overpower him, he better be careful. He may just run into something interesting.” For 12 years and many thousands of air miles, Doheny and Altamura have been through a lot. There have been the world title winning highs, the empty locker-rooms of defeat, rebuilding, restructuring and now this, what could amount to one last charge at world glory. This website may contain adult language. TM & © 2025 BoxingScene.All Rights Reserved. This website may contain adult language TM & © 2025 BoxingScene.All Rights Reserved LBV Magazine English Edition in the Lamalunga karst system near the town of Altamura in southern Italy an extraordinary archaeological discovery was made: a Neanderthal skeleton which is estimated to be between 130,000 and 172,000 years old The discovery was not only significant due to its age but also because of the exceptional state of preservation of the skeleton which is embedded in speleothem formations and covered by coral-like concretions The Lamalunga cave system is characterized by its geological complexity with formations of stalactites and stalagmites that have sealed the skeleton over millennia The Altamura Man was discovered in a small which has provided a unique environment that has favored the preservation of the skeletal remains but has greatly complicated their extraction and study Given the fragility of the site and the importance of the specimen researchers chose an in situ study approach employing advanced digital technologies to capture precise data without disturbing the environment the “KARST” project led these efforts using virtual anthropology techniques and digital imaging equipment specifically designed for challenging underground conditions One of the key innovations was the digital reconstruction of the Neanderthal’s skull researchers were able to virtually extract the skull from the speleothem formations creating a three-dimensional model that provides a detailed view of its morphology radiographic and endoscopic studies were conducted to examine the internal features of the skeleton and assess its state of preservation The Altamura Man represents one of the best-preserved Neanderthal fossils ever discovered Analysis of the skeleton has revealed a combination of archaic and classic morphological features suggesting an evolutionary complexity that could redefine our understanding of Neanderthal dispersal and adaptation in Europe The detailed study of the specimen’s teeth showed common dental pathologies indicating aspects of its diet and general health the anatomical features observed in the skeleton such as the cranial structures and scapula provide information about the morphological variability within the Neanderthal population The Altamura Man offers an unprecedented opportunity to explore the interaction between paleoecology and human evolution Its exceptional state of preservation allows scientists to investigate the environmental conditions and ecological factors that may have influenced Neanderthal life The context in which the skeleton was found also raises questions about Neanderthal behavior and use of space The arrangement of the skeleton suggests that the individual may have fallen into the cave or been placed there by other members of its group The latter could imply some form of ritual or cultural behavior although further research is needed to confirm such hypotheses Despite the significant advances made in the study of the Altamura Man The research faces logistical and ethical challenges related to the conservation of the site and the potential extraction of the remains for more detailed studies The researchers conclude that the most recent analyses have allowed us to determine that “Altamura Man” was an adult Neanderthal showing a number of archaic morphological features common with fossils from about 200,000 years ago found in Spain and yet also showing features of the later so-called “classic” Neanderthals from 60,000-40,000 years ago Today we can suggest with more confidence that the skeleton although disarticulated and covered with concretions making it the most informative Neanderthal specimen to date Researchers hope that with proper planning and the necessary courage the Lamalunga system can become a reference point in the study of human evolution and an example of how science and the community can work together to preserve paleoanthropological heritage Costantino Buzi, Marco Boggioni, et al., Virtual paleoanthropology in karstic environments. The challenging case of the Neanderthal skeleton from Altamura (southern Italy). Quaternary Science Reviews, Volume 338, 15 August 2024, 108833. doi.org/10.1016/j.quascirev.2024.108833 Subscribe to get the latest posts sent to your email. Archaeologists from universities in the United States and Denmark found, deep within the Actun Uayazba Kab cave in Belize, two small stone tools dated between 250 and 900 AD that… For centuries in China, men and women gathered to play a game called Cuju. Considered an ancient form of soccer, a pastime, but also a political tool, it played a… A team of researchers has succeeded in recreating for the first time in a laboratory experiment a phenomenon that until now only existed as a theory in the realm of… As part of a major construction project, the Cantonal Archaeology of Aargau carried out a rescue excavation between early May 2024 and the end of March 2025. 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You can also support us with a monthly subscription and receive exclusive content. 08 Mar 2025 16:30:00 GMT?.css-1txiau5-AnswerContainer{color:var(--GlobalColorScheme-Text-secondaryText2);}Team Altamura won 2–1 over Juventus Next Gen on Sat Predicted lineups are available for the match a few days in advance while the actual lineup will be available about an hour ahead of the match The current head to head record for the teams are Juventus Next Gen 0 win(s) Have scored 4 goals in their last 5 matches Who won between Juventus Next Gen and Team Altamura on Sat 08 Mar 2025 16:30:00 GMT?Team Altamura won 2–1 over Juventus Next Gen on Sat 08 Mar 2025 16:30:00 GMT.InsightsHave scored 5 goals in their last 5 matches Juventus Next Gen is playing home against Team Altamura on Sat Sign up for our daily Newsletter and stay up to date with all the latest news You are receiving this pop-up because this is the first time you are visiting our site You are using software which is blocking our advertisements (adblocker) we are relying on revenues from our banners So please disable your adblocker and reload the page to continue using this site.Thanks despite the challenges faced by the fresh-cut sector president and vice-president of the PO respectively explain the current trends in the baby leaf market and what is new in this sector The baby leaf production segment had a successful year in 2024 with the mild climate contributing to sufficient availability of the main references though there has been a notable increase in exports to eastern European countries which were previously considered marginal markets but there is a growing demand for oriental varieties which are increasingly used in cooking (Tatsoi which have already entered our assortment for a few years now," says Alfonso Altamura we aim to consolidate our market shares in both the fresh produce and fresh-cut segments The strategy is founded on two pillars: international expansion and the enrichment of the production portfolio we plan to expand the membership base and diversify the product range with new additions expected as early as the next summer season primarily yellow melons and watermelons," explains Fabio Altamura Op Altamura is optimistic about the future and is focusing on innovation and international expansion The company's participation in Fruit Logistica 2025 will be a pivotal opportunity to showcase its latest innovations we will be developing the theme 'The Green Pizza,' in collaboration with I Borboni Pizzeria a globally renowned name in the pizza industry The Green Pizza represents a vision of the future with a topping featuring baby leaf products as the primary ingredient The event will also feature renowned pizza artisans namely Daniele Ferrara and Valerio Iessi of Pizzeria I Borboni as well as Geppino Croce of Vicceria and Carmine Pierno of Pizzeria Stratto This collaboration represents an innovative opportunity to experience our products through one of the most popular and consumed products in the world while also paying homage to what symbolizes the essence of the Made in Italy concept," explains the Altamura brothers Op Altamura will be exhibiting at Fruit Logistica 2025 (Berlin For more information:Op Altamuravia PacinottiPontecagnano Faiano (SA) - Italy[email protected]www.opaltamura.com FreshPublishers © 2005-2025 FreshPlaza.com This website is using a security service to protect itself from online attacks The action you just performed triggered the security solution There are several actions that could trigger this block including submitting a certain word or phrase You can email the site owner to let them know you were blocked Please include what you were doing when this page came up and the Cloudflare Ray ID found at the bottom of this page A Neanderthal skeleton was discovered encased in rock in an Italian cave 30 years ago but it hasn’t been studied much due to a long-running impasse about how to safely excavate it By Michael Marshall The Altamura Man skeleton in Lamalunga cave This is an extract from Our Human Story, our newsletter about the revolution in archaeology. Sign up to receive it in your inbox for free every month. Have you heard of Altamura Man? Since it was new to me, I’m going to guess that you may be unfamiliar with it. Which is peculiar, because it’s an astonishing specimen. To find Altamura Man you would need to travel to Puglia (also known as Apulia) in southern Italy: if you think of Italy as looking like a boot, Puglia is… Explore the latest news, articles and features David Altamura will drop what he’s doing and head out to catch a wave SaveLog in or to save articleShareCopy link Share via...Gift this articleSubscribe to gift this article Gift 5 articles to anyone you choose each month when you subscribe David Altamura is the co-founder and CEO of health and wellness centre Wildsoul Wellness and owner fitness studio Globe Athletic How long have you been surfing and how did you get into it?I’ve been surfing for 30 years learning to surf in Byron is almost obligatory I worked at the Byron Bay Swimming Pool as a swim teacher so we were always given right of way at the Wreck Gift 5 articles to anyone you choose each month when you subscribe. Follow the topics, people and companies that matter to you. The NIOA Group has announced the appointment of experienced combat systems specialist Frank Altamura as it continues to expand its collaboration with the US defence industry The recently retired Project Director Joint Ammunition and Weapons Systems (PD JAWS) at Picatinny Arsenal joins NIOA as Business Development Manager – North America With extensive experience in weapons and protections systems munitions procurement and defence technology integration Altamura brings a wealth of knowledge to the company’s United States operations which include Tennessee-based Barrett Firearms Mr Altamura was instrumental in leading technical innovations developing Department of Defense policy and regulation adjustments and coordinating munitions logistics with foreign partners he managed development of the next generation of terrain shaping obstacle capability to meet the latest international agreements “We are thrilled to welcome Frank to our US team,” NIOA Group CEO Rob Nioa said “As we continue to strengthen and diversify our participation in the US defense industrial base Altamura said: “I’m excited to join the NIOA team The NIOA portfolio and allied nation customers coupled with an international partner base is a great fit for what I bring from my Army career It is also obvious that NIOA’s leadership promotes innovation and encourages creativity by team members I find their vision for the future as an exhilarating opportunity for me to help NIOA grow in the industry.” Mechanical Engineering from Stevens Technical Institute and Bachelor’s Degree Mechanical Engineering from New Jersey Institute of Technology as well as multiple executive leadership certificates NIOA has had a permanent office at Picatinny Arsenal the US Army’s garrison for armaments development and procurement Save my name, email, and website in this browser for the next time I comment. Δdocument.getElementById("ak_js_2").setAttribute("value",(new Date()).getTime()) Daily News Bulletin from APDR for 06/05/25 - India signs deal for Rafale Marine aircraft - APDR The Inter-Governmental Agreement between India and France has been signed for India’s acquisition of 26 Rafale Marine to equip the Indian Navy SPONSORED CONTENT: Facing the Evolving Needs of Maritime Security - APDR IAI Israel's premier defence corporation and a provider of naval and maritime solutions is at the forefront of maritime security New Zealand budgets for new naval helicopters - APDR New Zealand will spend NZ$2 billion (US$1.19 billion) in its upcoming budget to replace the Defence Force’s aging maritime helicopters Thales Australia wins top honour at defence industry awards - APDR Thales Australia recently won the prestigious Chief Minister’s Award for Excellence in Defence Industry – Large Business Daily News Bulletin from APDR for 05/05/25 - South Australia touts defence industry growth - APDR South Australia is leading the nation’s defence industry growth with the state’s economic contribution up 30 pct to $1.9 billion in 2023-24 Work starts on RAAF Base Darwin refresh project - APDR Defence has held a sod turning ceremony to acknowledge commencement of the RAAF Base Darwin Mid-Term Refresh project worth almost $160 million Δdocument.getElementById("ak_js_1").setAttribute("value",(new Date()).getTime()) South Korea’s Kim is a huge underdog and has the chance to record the upset of the year in the first major fight of 2025 when he meets Inoue on Friday at the Ariake Arena in Tokyo, Japan. Kim accepted Friday’s fight at less than two weeks’ notice after Inoue’s original foe Sam Goodman had to withdraw having suffered a cut in sparring. Kim, already on the bill, was on standby, and he has a motivation that echoes back to 1970s light-heavyweight great Matthew Saad Muhammad. Saad, one of the sport’s great warriors, was abandoned by his brother on the streets of Philadelphia when he was a small boy. Saad Muhammad, who first was known as Matt Franklin, grew up in an orphanage and eventually went into foster care, ensuring his life became an ongoing search for his identity and his family. Kim was also an orphan, but he was never adopted. He has battled the odds his entire life, and next has a fight for the undisputed junior-featherweight title. The 32-year-old is 21-2 (13 KOs). “Many of you wouldn’t know that Joon is an orphan,” said Altamura. “He was never adopted. He was undersized as a kid. “He was viciously bullied throughout his upbringing and yet here he is, on the biggest stage of the world, from the orphanage to the undisputed world championship, and I think that that’s an incredible accomplishment and it speaks volumes about the kind of person he is.” Altamura is a fight historian and knows all about Saad Muhammad’s unlikely story – from the streets of Philadelphia to the walls of the International Boxing Hall of Fame. The Australian knows Kim has a lot to do, too, but Altamura also recognises that Kim has already come through a lot to be there. “Our message is to all the troubled kids in the world, to the orphans, I want you to know that there’s brighter days ahead,” he said. “You are loved, tomorrow the sun will rise, so never lose hope and this man right here is the embodiment of if you never lose hope, good things can happen in your lives.” From the fresh market to the fresh-cut sector from edible flowers to watermelons and melons is looking forward to summer with a strategy of growth on several fronts Following a successful winter season for baby leaf products the company is preparing for a summer campaign by introducing new products such as watermelons there is a growing interest in edible flowers where the Mama Salad brand aims to strengthen its presence in Europe This dynamic environment is marked by a constant state of flux Vice President of the producers' organization has provided a thorough overview of the current situation as well as the future strategies Baby leaf: A resilient market despite the uncertain climateThe baby leaf sector has demonstrated its strength and dynamism even in the face of the challenges posed by climate change "The most recent winter campaign showed a positive trend," explains Altamura The mild weather conditions during the winter months contributed to optimal production and despite the fluctuations in weather patterns in March the quality of the product remained consistently high These results attest to the organizational and agronomic skills of the members who are able to maintain high-quality standards even in conditions that are not always ideal appreciated both for its versatility in the kitchen and because it is in constant demand from the large-scale organized distribution and foreign markets." A trend that strengthens Op Altamura's market position in the ready-to-eat salad segment and yellow melonsOp Altamura's offerings extend beyond baby leaf products the company's associates will expand the offer with watermelons one of our associates specializes in the production of yellow melon with over 150 hectares cultivated and a harvest scheduled from mid-June to the beginning of October," says Altamura Altamura is introducing watermelons and mini-melons which will be distributed under the 'Altamura OP' brand The total area allocated to these crops reaches 200 hectares We are in the final stages of planning with our customers." and exportsEdible flowers are becoming increasingly popular This positive trend has prompted us to expand our production and add new varieties to our range in order to meet the needs of the catering The appeal of edible flowers lies in their vibrant colors making them a strategic and rapidly expanding product They symbolize innovative and quality-driven agricultural practices Fresh-cut segment: A growing trend and the opening of new marketsWhile the company continues to focus on the production and commercialization of fresh baby leaf it is developing a fresh-cut segment to further differentiate itself in the eyes of its customers the first ready-to-eat line launched by the producers' organization in 2022 is strengthening its presence both in Italy and abroad the fresh-cut segment contributes 10% of our total turnover We have a strong presence in several European markets particularly in the Benelux region and Germany and we are committed to further expanding our international footprint," Altamura stated The ready-to-eat fruit and vegetable sector is no longer a passing trend; it is a concrete answer to the convenience needs of today's consumers Upcoming trade fairs: PLMA and Fruit Attraction in the spotlightOp Altamura's strategic growth plan includes active participation in industry events we will have our own stand at Fruit Attraction in Madrid," concludes Altamura Credits photo article: TMH Studio www.todisco.media For more information:Op AltamuraVia PacinottiPontecagnano Faiano (SA) - Italy[email protected]www.opaltamura.com Thank you!We have emailed you a PDF version of the article you requested You can also addto your safe senders list to ensure you never miss a message from us IFLScience HomeThe Most Complete Neanderthal Skeleton Ever Found Still Can't Be ExcavatedComplete the form below to listen to the audio version of this article IFLScience needs the contact information you provide to us to contact you about our products and services You may unsubscribe from these communications at any time For information on how to unsubscribe, as well as our privacy practices and commitment to protecting your privacy, check out ourPrivacy Policy IFLScience HomeJoin for Exclusive FacebookemailBenjamin holds a Master's degree in anthropology from University College London and has worked in the fields of neuroscience research and mental health treatment. Facebookemail EditedbyMaddy ChapmanMaddy Chapman Facebook emailMaddy is an editor and writer at IFLScience with a degree in biochemistry from the University of York Altamura Man's features aren't like most other Neanderthals Image credit: Costantino Buzi et al., Quaternary Science Reviews, 2024 (CC BY 4.0) a strangely atypical Neanderthal man has been stuck upside down for around 150,000 years this remarkable skeleton represents one of the most spectacular human fossils ever discovered and could help to clear up some of the mysteries surrounding our evolution as a species – if only we could get the old bloke out The inverted skull of this peculiar specimen was first spotted poking out of a wall within the Lamalunga karstic system researchers were struck by the skeleton’s unusual orientation and gnarly appearance caused by the accumulation of calcite blobs – otherwise known as "cave popcorn" – upon the surface of the cranium Unfortunately, however, the bones have completely fused with the surrounding rock, leaving Altamura Man sealed within his natural tomb Summarizing the ancient hominid’s frustrating predicament the authors of a new paper explain that the skeleton “still lies deep within a spectacular cave setting partly embedded within speleothems and extensively covered by coralloid concretions.” “These peculiar location and conditions would entail major difficulties in excavating and preserving ex-situ this skeleton,” they add Powerless to get their man out of his speleo-prison and into a lab researchers were unable to study this intriguing individual for several decades although uranium-thorium dating did reveal that he was between 130,000 and 172,000 years old and miniature laser scanners that could fit through tiny openings in the rock wall The combined results of these studies revealed that Altamura Man was a “fully adult Neanderthal who suffered some rather common dental pathologies,” leaving him with several teeth missing a digital reconstruction of the skull demonstrated that the skeleton possessed a number of morphological features that had never previously been seen in “classic Neanderthals” A reconstruction of Altamura Man's face.Image credit: Roberto Montanari/Shutterstock.comFor instance the skull bore similarities to that of an older hominid that lived in a Spanish cave around 430,000 years ago and which has been classified as an early type of Neanderthal Altamura Man was more akin to other members of his species Based on this mish-mash of characteristics researchers believe Altamura Man probably belonged to an isolated population of Italian Neanderthals that evolved separately from those elsewhere in Eurasia and which preserved some of its more archaic traits for an exceptionally long time it’s thought that this particular individual probably died after falling into a sinkhole and getting stuck in a crevice where he has remained ever since – and is likely to stay forever more The study is published in the journal Quaternary Science Reviews Humans T. Rex Handbags Could Soon Be A Thing, Ronan The Sea Lion Has Better Rhythm Than Some Humans, And Much More This Week2 days agolink to article ancient ancestors Human Wounds Heal Nearly 3 Times Slower Than Other Animals': Could This Be Due To Our Evolution?3 days ago150link to article T. Rex Leather, Glow-In-The-Dark Gas Clouds, And Musical Sea Lions link to article The Five Most Common Headaches link to article © 2025 IFLScience. All Rights Reserved. RSS Murray Bridge High School student Abby Altamura has won an innovation award for her sustainable business idea This story is now free to read. Help Murray Bridge News tell more stories like this by subscribing today What started out as a "basic idea" for an innovative business has won local high school student Abby Altamura an award was presented at the school's presentation night last Monday "Trying to get (the cases) customisable while getting sustainable materials took a lot of research," she said "The back was interchangeable and it included different attachments like card holders." Abby's plan for her phone case business was to have fully sustainable edges of the case and interchangeable compostable backings and then you could keep swapping out the back," she said A 30-page folio included the plan for the business Abby looked at ways it might be possible to continue her idea outside of the classroom but there were a lot of factors to consider "Looking a manufacturers overseas and such but there's not a lot of people who do interchangeable phone cases," she said Initially Abby was actually in another class but decided to go into business innovation two weeks into the school year but I thought I might as well try it and it was actually alright," she said She also took home the year 12 creative arts subject award on the night I think my mouth opened and the principal was standing there laughing at me," Abby said The award presentations were a reminder of how far each graduate has come and how bright their futures are A highlight of the night was each student’s name being called up so they could walk across stage to receive their well-deserved graduation certificates Holly Lynch and Riley Hagger receiving their awards at the MBHS presentation night Andriana Karras and Megan Clothier receiving their awards on presentation night Read more about the night award winners at www.mbhs.sa.edu.au photographers and other artists from around the Murraylands have shared $4300 worth of prizes at the annual awards Lee Spurling invites you to come and play eight-ball in Murray Bridge Residents across the district are being invited to contribute to a feasibility report on services in the region Take a behind the scenes look at a movie shooting in Old Tailem Town last Thursday Metrics details Complete Neanderthal skeletons are almost unique findings A very well-preserved specimen of this kind was discovered in 1993 in the deepest recesses of a karstic system near the town of Altamura in Southern Italy We present here a detailed description of the cranium after we virtually extracted it from the surrounding stalagmites and stalactites The morphology of the Altamura cranium fits within the Neanderthal variability though it retains features occurring in more archaic European samples Some of these features were never observed in Homo neanderthalensis in fossil specimens dated between 300 and 40 ka Considering the U-Th age we previously obtained (>130 ka) the morphology of Altamura suggests that the archaic traits it retains may have been originated by geographic isolation of the early Neanderthal populations from Southern Italy On-going debate about these models involves integration and stochastic occurrence of Neanderthal features Photographic probes (a) were used to acquire photogrammetrically the basal and posterior components (BP) of the cranium (b) Its frontal and facial parts (FF) were acquired by laser scanner from the Apse (c) where also the mandible and several long bones are directly visible on the cave floor (c we describe and contextualise its overall external morphology within the European human variability of the Middle and early Late Pleistocene The inside of this chamber— containing a few human bones belonging to the same skeleton—can only be observed with difficulty through a few narrow gaps in the speleothem curtain The cranium is cemented upside down within the speleothem curtain with stalagmites adhering to its sides; its anterior part faces the Apse whereas the rear and the base face the Back-chamber cranial base and most of the cranial vault BP) is accessible only via indirect inspection with probes through the gaps in the speleothem curtain whereas a uniformly thin calcite layer coats the rear and the base including the whole occipital bone where the anatomical structures are consequently more clearly visible a Homologous landmark configurations were acquired on the FF and BP of Altamura and of a reference specimen the nearly complete Cranium 5 from the Sima de los Huesos site (SH-5); b landmark coordinates were processed separately by Generalised Procrustes Analysis (GPA); c FF and BP were aligned according to the reference specimen showing the highest morphological affinity; d–f various views of the virtual model of Altamura aligned on SH-5; g SH-5 lateral view is quantitatively closer to “early” (ERN) than to “classic” (EWN) Neanderthals: this result is definitely consistent with its chronology which clearly predates the Late Pleistocene Even the facial morphologies of Altamura and SH-5 show similar receding zygomatic arches and frontal squama whereas they differ in the morphology of the supraorbital arches the cranial architecture of Altamura looks like an antero-posteriorly “stretched” variant of SH-5 different orientation of the mastoids and different shape of the browridges Full circles represent fossil specimens; orange: virtual reconstructions of Altamura based on SH-5 (Alt-SH-5) on the mean shape of the EWN sample (Alt-ENW) and on Saccopastore 1 (Alt-Scp1); blue: Mid-Pleistocene specimens (SH-5: Sima de los Huesos 5; Petr: Petralona); green: Homo neanderthalensis (Amd: Amud; Gua: Guattari 1; LaFer: La Ferrassie; LaCha: La Chapelle; Scp1: Saccopastore 1; Sha: Shanidar); grey: Homo sapiens c Cranial morphology associated at extreme negative (−) and positive (+) values of the first three principal components; yellow and violet respectively indicate local expansion and contraction from the mean shape but show a closer affinity with the Neanderthal morphology when discrete apomorphic traits are considered 3D map variations of the occipital squama showing Altamura compared to the average morphology of Homo neanderthalensis (a) Mid-Pleistocene humans (b) and Homo sapiens (c) Colour maps are reported in posterior and lateral view Warm and cold colours indicate respectively which regions in the three average morphologies are respectively locally contracted and expanded compared to Altamura may shed light on the origin and evolutionary pattern of the Neanderthals suggesting that Neanderthal populations lived in southern Italy during MIS 6 a time span characterized by cold temperatures which do not seem belong to the “Neanderthal lineage” the relatively small endocranial capacity is not at all the unique trait differentiating Altamura from the ERN and EWN samples suggesting that examples of variable degrees of similarity (or diversity) with the Neanderthal morphology existed simultaneously in separated regions it seems to us that the “accretion model” explains Neanderthal evolution only when a non-linear and ecologically-driven perspective is considered taking into account the geographic distribution of the fossil record environmental isolation and local extinctions DTA finds the best fit in aligning two disarticulated models by using a comparative sample as reference This method includes the following steps: (i) symmetrisation of the landmark configurations (ii) scaling of the reference configuration to the size of the target set generalized Procrustes analysis) between the scaled reference and the target configuration (iv) calculation of the cumulative morphological distance between the two aligned configurations (i.e. the comparative specimen with greatest morphological affinity to Altamura was used as reference to align (translation and rotation) the two disarticulated cranial fragments since these landmarks are not clearly visible We performed three virtual reconstructions of Altamura using for reference the models of SH-5, Saccopastore 1 and the mean of EWN (Fig. 3 and Supplementary Data Fig. 5) We assessed the phenetic affinity of Altamura among the comparative sample performing a PCA by using a set of 28 anatomical landmarks In the PCA we used the covariance matrix built on the comparative sample we performed an ordinary Procrustes analysis to register the shapes of the three virtual reconstructions of Altamura on the mean shape of the comparative sample the registered landmark configurations of Altamura (based on the three models) were projected to predict its PC scores values The nexus data matrix was processed with PAUP version 4.0b1048 using the Maximum Parsimony and the Neighbour-joining algorithms We limited our analysis to features visible on the 3D reconstruction of the Altamura cranium; however the score of five of these was assigned only tentatively because overlying concretions may have altered or partially obscured the original morphology Three of these five uncertain features were assigned to the “Neanderthal condition” position of the external auditory meatus on the same horizontal plane as the temporal zygomatic process (feature n. 17, Supplementary Data Table 4); this feature is typical of EWNs whereas it is not fully expressed in both Saccopastore specimens It is worth mentioning that only the left meatus is visible in Altamura (the right one is covered by speleothems and cannot be acquired digitally) as well as part of the zygomatic bar of the same side; shape and depth of the mandibular fossa (feature n. 18, Supplementary Data Table 4); the fossa is preserved only on the left side and is partially filled with concretions; shape and position of the foramen magnum (feature n. 19, Supplementary Data Table 4) Also in this case the sample of Saccopastore looks less derived than Altamura which resembles shape and position of the foramen magnum in Saccopastore 1 The method is based on building closed polygonal chains lying on equidistant parallel planes cutting the mesh The planes are set perpendicular to the axis defined by the maximum cranial length calculated as glabella-opistocranion chord a number of equidistant contour curves (polylines) are drawn on the cranium We used the morphology of this set of curves to highlight the anatomical features of Altamura Polylines were digitally defined using Mimics (Materialise NV Belgium) on each specimen by calculating a series of non-overlapping closed polygons spaced by 2.0 mm We used SH-5 from Atapuerca for reference in aligning the mid-sagittal planes (glabella the evenly-spaced polylines were automatically generated starting from the opistocranion and the topology of the occipital squama was returned Further information on research design is available in the Nature Portfolio Reporting Summary linked to this article All data needed to evaluate the conclusions of the paper are present in the article and Supplementary Data Data and R code are available at 10.6084/m9.figshare.21900495 On the phylogenetic position of the pre-Neandertal specimen from Reilingen A Middle Pleistocene Homo from Nesher Ramla in Neanderthals Revisited: New Approaches and Perspectives (eds Hublin Neandertal roots: cranial and chronological evidence from Sima de los Huesos A Pliocene‐Pleistocene stack of 57 globally distributed benthic δ18O records The Neanderthal in the karst: first dating and paleogenetic data on the fossil skeleton from Altamura (Italy) The pre-modern human fossil record in Italy from the Middle to the Late Pleistocene: an updated reappraisal Three-dimensional topographic survey of the human remains in Lamalunga Cave (Altamura In situ observations on the dentition and the oral cavity of the Neanderthal skeleton from Altamura (Italy) High‐resolution synchrotron X‐ray fluorescence investigation of calcite coralloid speleothems: elemental incorporation and their potential as environmental archives Distinct among Neanderthals: the scapula of the skeleton from Altamura New tool for digital alignment in virtual anthropology The Sima de los Huesos crania (Sierra de Atapuerca Virtual reconstruction and comparative analyses of the Middle Pleistocene Apidima 2 cranium (Greece) in Brain Endocasts—The Paleoneurological Evidence (eds Holloway Paleoneurology of an “early” Neandertal: endocranial size Geometric morphometric variability in the supraorbital and orbital region of Middle Pleistocene hominins: Implications for the taxonomy and evolution of later Homo A new age within MIS 7 for the Homo neanderthalensis of Saccopastore in the glacio-eustatically forced sedimentary successions of the Aniene River Valley Caractères dérivés de la région occipito-mastoïdienne chez les Néandertaliens A re-examination of presumed Neandertal-like fossils Past extinctions of Homo species coincided with increased vulnerability to climatic change Better support for a small effective population size of Neandertals and a long shared history of Neandertals and Denisovans A high-coverage Neandertal genome from Vindija Cave in Croatia Fragmentation of Neanderthals’ pre-extinction distribution by climate change Morphological description and comparison of the dental remains from Atapuerca-Sima de los Huesos site (Spain) The accretion model of Neandertal evolution Humans of the Middle Pleistocene: The controversial calvarium from Ceprano (Italy) and its significance for the origin and variability of Homo heidelbergensis Virtual ancestor reconstruction: revealing the ancestor of modern humans and Neandertals New age estimates for the Swanscombe hominid and their significance for human evolution The new chronology of the Ceprano calvarium (Italy) A mitochondrial genome sequence of a hominin from Sima de los Huesos Nuclear DNA sequences from the Middle Pleistocene Sima de los Huesos hominins New bracketing luminescence ages constrain the Sima de los Huesos hominin fossils (Atapuerca Apidima Cave fossils provide earliest evidence of Homo sapiens in Eurasia The impact of a date for understanding the importance of Homo naledi Digital reconstruction of the Ceprano calvarium (Italy) Glacial refugia of mammals in Europe: evidence from fossil records Climate refugia: Joint inference from fossil records species distribution models and phylogeography Statistical Shape Analysis: with Applications in R Vol a new algorithm for fully automatic extraction of cranial endocasts and the calculation of their volumes in Statistical Shape and Deformation Analysis (eds Zheng A Companion to Paleoanthropology (John Wiley & Sons The Neanderthal endocast from Gánovce (Poprad Virtually estimated endocranial volumes of the Krapina Neandertals in Effective Computational Geometry for Curves and Surfaces (eds Boissonnat Arothron: An R package for geometric morphometric methodsand virtual anthropology applications R Core Team, R: a language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. https://www.R-project.org/ (2019) Download references This research was funded by the Italian Ministry of Education as well as the Parco Nazionale dell’Alta Murgia and the municipality of Altamura for their combined contribution to the study of the Altamura skeleton We are indebted to the speleologists of the C.A.R.S (Centro Altamurano Ricerche Speleologiche) for their valuable assistance during the operations in the cave and a second reviewer for the constructive suggestions that have greatly improved this paper Catalan Institute of Human Paleoecology and Social Evolution (IPHES-CERCA) Natural History Museum – Palazzo Nonfinito Centre for the Exploration of the Deep Human Journey Centro Mixto UCM-ISCIII de Evolución y Comportamiento Humanos designed the research and interpreted the results; G.M. had a central role in planning the digital acquisition in situ of the skeletal elements; A.P. performed the virtual reconstruction of the Altamura cranium; A.P. reviewed and edited the original draft; G.B. revised and edited the final draft of this paper The authors declare no competing interests Communications Biology thanks Rolf Quam and the other reviewer(s) for their contribution to the peer review of this work Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Download citation DOI: https://doi.org/10.1038/s42003-023-04644-1 Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily. Play Duration: 2 minutes 37 seconds2m 37sBrought to you by In a warehouse in Port Adelaide, Michael Altamura is up early preparing for Sauce Day. It's an annual celebration that is as much about family, as it is about the 1,400 jars of preservative-free passata he produces. "There's about five families all together", Altamura said. "Everyone gets into it". Michael Altamura is making 1,400 jars of passata with five families at his warehouse in Port Adelaide on Sauce Day.(Troy Sincock, ABC) Published: 10h agoMon 5 May 2025 at 8:00pm Download the ABC listen app to text and call your favourite live radio 27 Apr 2025 18:00:00 GMT?.css-1txiau5-AnswerContainer{color:var(--GlobalColorScheme-Text-secondaryText2);}Avellino won 2–1 over Team Altamura on Sun The current head to head record for the teams are Avellino 1 win(s) Who won between Avellino and Team Altamura on Sun 27 Apr 2025 18:00:00 GMT?Avellino won 2–1 over Team Altamura on Sun 27 Apr 2025 18:00:00 GMT.InsightsHave scored 8 goals in their last 5 matches Avellino is playing home against Team Altamura on Sun they found an upside-down human skull fused into the rock alongside a large collection of other human bones The skull’s jutting brow was covered in a layer of pearl-like coralloid calcium deposits otherwise known as cave popcorn Much of the remains were covered in some form of the mineral that had leached down from the surrounding limestone scientists believe the person (the “Altamura Man”) had fallen through a sinkhole in the surrounding limestone karst and never made it back out again In the early going, no one knew if the skeleton had belonged to an early Homo sapiens human or Neanderthal, and given its remote location, serious scientific study was slow to come. In 2009 a group of researchers received permission from Italian authorities to remove a piece of its right shoulder blade in an attempt to understand who this unlucky person had been When the team – which hailed from universities in Italy Spain and Australia – examined the full skeleton they found it to be remarkably intact and mostly visible from the tunnel despite the rampant calcification The remains rested in what came to be called the “Apse of Man,” named for the large domed area of a church that rises above the altar. Behind the Apse, scientists say lies an unreachable “back chamber” that contains a few of the man’s bones The team initially tried to date the shoulder blade by extracting its collagen but they couldn’t find enough to pass through an accelerator mass spectrometer Read More: Who Were the Neanderthals? they began to pursue a different strategy and collected calcium deposits from bones still in the cave along with a stalagmite already found broken The researchers aimed to date the skeleton by first dating the deposits which had dripped onto the bones over thousands of years they tested the calcium and estimated that the Altamura Man was between 130,000 years and 172,000 years old placing it among the oldest Neanderthal fossil ever found A further examination of the set classified them as belonging to an “Early Neanderthal” with a mixture of archaic and later features Attempts at DNA analysis using the shoulder blade fell short of the researchers’ hopes but tests did confirm that the Altamura Man was a Neanderthal Read More: The Fascinating Path of Neanderthal Evolution: Where Did Neanderthals Come From? For a 2020 study scientists snaked a videoscope into the skull’s mouth and estimated that the Altamura Man had been a younger adult at the time of his death he’d suffered from poor oral health and had lost at least two teeth during his lifetime who appear to have mostly enjoyed healthy teeth The skeleton continues to attract study as the most complete Neanderthal fossil yet found even though much of it remains encased in rock In March 2023, a paper attempted to digitally reconstruct the skull which possessed both newer (in Neanderthal terms) and archaic features putting it at odds with its own time period "the remnant of an archaic population which was probably not in simple continuity with the Neanderthal lineage,” the paper says Read More: How Much Neanderthal DNA Do Humans Have? Register or Log In Want more?Keep reading for as low as $1.99 Subscribe Save up to 40% off the cover price when you subscribe to Discover magazine. Volume 10 - 2023 | https://doi.org/10.3389/fvets.2023.1148673 This article is part of the Research TopicNew Insights in Veterinary Cancer ImmunologyView all 10 articles the evidence of a co-causative role of FcaPVs in the development of FOSCC is as follows: 1) Different FcaPV types (-1/-2/-3/-4/-5) exhibit mucosal tropism (16, 21) 2) A subset of FOSCC samples is associated with FcaPVs DNA (11–14, 19, 20) 3) Detection of FcaPVs DNA in a subset of FOSCC is a common finding in different geographical areas, as per independent studies by different research groups (11–14, 19, 20) 4) There is histological, molecular and immunohistochemical evidence of PV active infection in a subset of FOSCC by different research groups (13, 15, 19) 5) FcaPV-2 displays high viral load and expression of E6E7 oncogenes in FOSCC samples (10, 19) 6) FcaPV-2 DNA is detectable and viral oncogenes are expressed in FOSCC-derived cell lines (18) 7) FcaPV-2 E6 and E7 oncoproteins exert transforming properties by impairing p53 and pRb pathways in feline living cells (10, 18, 22) 8) FcaPV-3 induces cellular changes compatible with PV-induced cancer and displays high viral load in FOSCC (13, 14) Schematic diagram showing the diagnostic workflow proposed in this article Follow up of biological behavior and response to therapies of FcaPV-positive vs FcaPV-negative tumors would help to understand whether the former constitutes a different oncological entity compared to the latter and possibly pave the way to de-escalation strategies we believe it is time to begin studies in domestic feline clinical behavior and response to therapies of FcaPV-related FOSCC this would help to ameliorate the approach of the veterinary oncologists in terms of diagnosis therapeutic and prognostic evaluation toward feline patients We are used to think of comparative oncology as the discipline in which studies on animal models pave new ways in human medicine this would be the case were the “human model” traces the path for feline oncology although we do not yet know what lies at the end of the road All authors contributed to the article and approved the submitted version This work was financially supported by a grant from the Board of Directors The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher Human papillomavirus and oropharyngeal cancer PubMed Abstract | CrossRef Full Text | Google Scholar PubMed Abstract | CrossRef Full Text | Google Scholar Equine papillomavirus type 2: an equine equivalent to human papillomavirus 16 Comparison of the levels of equus caballus papillomavirus type 2 (Ecpv-2) DNA in equine squamous cell carcinomas and non-cancerous tissues using quantitative pcr Tumor cell plasticity in equine papillomavirus-positive versus-negative squamous cell carcinoma of the head and neck The presence of bovine papillomavirus type 4 DNA is not required for the progression to the malignant state in cancers of the alimentary canal in cattle Malignant transformation of a canine papillomavirus Type 1-induced persistent oral papilloma in a 3-year-old dog Malignant transformation of canine oral papillomavirus (Cpv1)-associated papillomas in dogs: an emerging concern Genomic characterisation of canine papillomavirus type 17 a possible rare cause of canine oral squamous cell carcinoma Transforming properties of felis catus papillomavirus type 2 E6 and E7 putative oncogenes in vitro and their transcriptional activity in feline squamous cell carcinoma in vivo Investigation of multiple felis catus papillomavirus types (-1/-2/-3/-4/-5/-6) Dnas in feline oral squamous cell carcinoma: a multicentric study Comparison of prevalence of felis catus papillomavirus type 2 in squamous cell carcinomas in cats between Taiwan and Japan In situ squamous cell carcinoma of the gingiva and nictitating membrane associated with felis catus papillomavirus type 3 in a cat A virome sequencing approach to feline oral squamous cell carcinoma to evaluate viral causative factors Histopathological investigation of feline oral squamous cell carcinoma and the possible role of papillomavirus infection mucosal tropism: the papillomavirus paradigm comes to an “and” Felis catus papillomavirus Type 2 E6 oncogene enhances mitogen-activated protein kinases and akt activation but not egfr expression in an in vitro feline model of viral pathogenesis Felis catus papillomavirus type-2 E6 binds to E6ap promotes E6ap/P53 binding and enhances P53 proteasomal degradation Detection of felis catus papillomavirus type-2 DNA and viral gene expression suggest active infection in feline oral squamous cell carcinoma Presence of papillomavirus DNA in feline squamous cell carcinoma and injection site-sarcoma Part 2: Pre-Neoplastic Neoplastic Dis Vet J Telomerase reverse transcriptase (Tert) expression and expression of matrix metalloproteinases (Mmp)-1/-2/-9 in feline oral squamous cell carcinoma cell lines associated with felis catus papillomavirus type-2 infection Feline oral squamous cell carcinoma: a critical review of etiologic factors management of head and neck cancer in the era of human papillomavirus: educating our patients on human papillomavirus and prognosis of head and neck squamous cell carcinoma Treatment preferences in human papillomavirus-associated oropharyngeal cancer Evolving role of human papillomavirus as a clinically significant biomarker in head and neck squamous cell carcinoma Animal models of head and neck squamous cell carcinoma Hpv related head and neck squamous cell carcinoma: new evidences for an emerging spontaneous animal model Hpv-associated oropharyngeal cancer de-escalation strategies and trials: past failures and future promise Anti-Egfr monoclonal antibody cetuximab displays potential anti-cancer activities in feline oral squamous cell carcinoma cell lines immunostaining is predictive of longer survival time in cats with oral squamous cell carcinomas Localization of felis catus papillomavirus type 2 E6 and E7 Rna in feline cutaneous squamous cell carcinoma Use of fluorescence in situ hybridization to detect felis catus papillomavirus type 2 in feline bowenoid in situ carcinomas and 5 in feline bowenoid in situ carcinoma: an in situ hybridization study Citation: Altamura G and Borzacchiello G (2023) Feline oral squamous cell carcinoma and Felis catus papillomavirus: is it time to walk the path of human oncology Received: 20 January 2023; Accepted: 02 May 2023; Published: 17 May 2023 Copyright © 2023 Altamura and Borzacchiello. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) distribution or reproduction in other forums is permitted provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited in accordance with accepted academic practice distribution or reproduction is permitted which does not comply with these terms *Correspondence: Giuseppe Borzacchiello, Ym9yemFjY2hAdW5pbmEuaXQ= Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher 94% of researchers rate our articles as excellent or goodLearn more about the work of our research integrity team to safeguard the quality of each article we publish Frank Grillo (left) with Salvatore Calabrese Frank Grillo created his Altamura vodka to showcase the flavour of the special wheat that is its base It’s amazing how often I wake up and think: ‘I’m living in Italy making vodka?’” These are the candid words of Frank Grillo who founded Altamura Vodka less than two years ago following a successful career in marketing Grillo and his partner relocated from the States to Puglia after baking a loaf of Pane di Altamura bread Grillo was inspired by the idea of a local wheat-based vodka “I thought it would be fun to make a vodka using the same local wheat used to make Pane di Altamura It’s the only bread in the world with a PDO and the plan was to only use the exact wheat which you’re allowed to use to make Pane di Altamura and express it through the vodka,” says Grillo I’m more of a bourbon and rye drinker and I have plans to make American-style wheat whiskies here as well But it was important that we started with vodka because it’s the best way to express the terroir of Altamura and our concept Our vodka will always be the focal point of the business.” Over the past couple of years Grillo has been showcasing his vodka at the major bar trade shows and awards ceremonies around the world And while the vodka leaves an impression on elite bartenders so too does Grillo with his bright blue hair and eccentric attire “I really wish there was a cool story behind the hair but really I just saw it in a copy of GQ magazine and went with it This invasion is reflective of Altamura’s demand on Grillo he now has just one outstanding marketing client and the rest of his time is spent running “We want to be working with the upper echelons of the on-trade Our first collaboration was with Maybe Sammy and we’ve been lucky enough to do a takeover at Paradiso as well as other top bars We’re also expanding into new markets where the on-trade is thriving such as South America – it’s important not to rely on just one or two markets “I don’t ever want to become removed from the brand I think it’s important that myself and Steven [Acuña co-founder] remain at the heart of the business We’re producing more vodka in the next distillation run than we sold all of this year which is a huge increase in operations.” With the construction of a new distillery underway and plans for wheat-based whiskies and gin in the future the ambition for Altamura is growing at the same pace as its volumes “I’ve become less shy about saying this but I believe we can be a global contender I believe we’re earning the right to sit on bar shelves next to Grey Goose and Belvedere and become a product of that scale “We need to prove the staying power of Altamura and operate successfully across different markets simultaneously in order to hit the next stage but I don’t think you can grow at that level in today’s world independently.” Grillo carries an endearing combination of modesty practicality and raw ambition which has taken Altamura to such heights in a short time I think it’s a combination of having a great product but also getting a lot of luck at the same time but we’ve played the hand well.” The latest digital edition can be found here You will need to log in/register to view it The pricing structure of non-alcoholic spirits has a high level of elasticity - there’s already a broad spectrum of price points which consumers are trying to navigate The co-founder of Altamura Distilleries in Italy’s Puglia region discusses the company’s plans to expand into new markets and spirits categories Which markets is Altamura Vodka available in and where would you like to launch into What flavours are derived from using local wheat to make the vodka The durum wheat of Altamura gives the vodka a certain umami that I like to describe as the flavour of sautéing mushrooms and finishing them with some vermouth. The mouthfeel is creamy, and it finishes with an elegant smoothness. In the just released Vodka Masters results the vodka was described as having a ‘luxurious’ texture lending itself to both savoury and sweet cocktails I highly recommend a classic Martini served in the style of The American Bar at The Savoy: three parts vodka The umami in the vodka pairs exceptionally with the flavours of a great dry vermouth The on-trade is enormously important to us – we have focused extensively on engaging the highest echelons of the mixology world and the mixologists are the artists that use our paint to create liquid art We think the unique profile and mouthfeel of our vodka can be an inspiration in cocktail making We have engaged with some of the most renowned names in mixology: Paradiso the Atrium Bar at the Four Seasons Florence and the Aman Venice We participate in important trade events like Tales of the Cocktail and we are always seeking opportunities to support guest shifts in all of our markets Tell us about your plans to move into gin and whisky Beyond our vodka we will produce gin and American-style whiskies using the exact same wheat that we use in our vodka We intend on distilling and racking the whisky in Altamura We’ll distil the first whisky in 2024 also but that will be in the barrel for at least four years before release With the strong interest in flavoured vodkas we intend to introduce a few Altamura options that respect the terroir it comes from We’re looking at savoury profiles like a tomato vodka using Datterini tomatoes and a green pepper vodka using mild Friggitelli both of which are grown in Puglia as examples How are plans progressing to open a gin and vodka distillery in Puglia We expect to begin distilling in Puglia in mid-2024 What do you have planned for the year ahead It’s about continued execution as we expand our market presence and also make the vodka available in more formats like one-litre and 500ml bottle sizes This interview can be found in the October 2023 issue of The Spirits Business magazine We are using cookies to give you the best experience on our website You can find out more about which cookies we are using or switch them off in settings This website uses cookies so that we can provide you with the best user experience possible Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful Strictly Necessary Cookie should be enabled at all times so that we can save your preferences for cookie settings we will not be able to save your preferences This means that every time you visit this website you will need to enable or disable cookies again db speaks to Altamura Distilleries managing director Frank Grillo to discover how the brand is utilising Puglia’s ancient wheat varieties to create vodka Despite his Sicilian heritage and sharing a surname with one of the island’s best-known grape varieties US-born Grillo is blazing a trail for spirits When asked how he ended up in the heel of the Apennine Penisula When we were looking where to move in Italy and Puglia flies to the top pretty quickly when it comes to that we said ‘let’s go’.” Puglia is already renowned for the quality of its bread and no meal in the region is complete without a healthy portion of crusty carbohydrates perhaps accompanied by a generous glass of Primitivo and plenty of locally-produced olive oil made from wheat sourced from Alta Murgia National Park in the province of Foggia has the rare distinction of being the only PDO-certified bread in the world Duilio and Simeto are known for their hardiness and complexity of flavour It was the quality of the bread that convinced Grillo that Pugliese wheat also had the potential to be transformed into something stronger: “We were going for expressing the flavour and the terroir of the wheat we weren’t looking to be a taste neutral I don’t say that in a disparaging way The original thought about Altamura Vodka was if you boiled a loaf of bread so the mission was to let people experience Altamura in a liquid format Altamura Distilleries has sourced its wheat through the godfather of grain The third generation to farm the fields of Altamura Cappiello’s instinctive knowledge of his crop gave him the confidence to participate in the project: “If you can make the best bread in the world the spirit is actually distilled in Poland Here [in Puglia] we’re going to first build out the gin distillery and then the vodka distillery We didn’t know what reception the product was going to get so we’ve started with a contract distiller to get set up We ship all the wheat from Altamura to Poland and then ship the vodka back to Italy.” the secret to distillation is finding what’s ‘just right’: “When we did our tastings we were choosing between distilling it two Five was too much because it stripped out everything it wasn’t as smooth as we would have liked it’s triple distilled and filtered five times through active charcoal.” “The Italians use the word ‘morbida’ to describe cheese and it means somewhere between smooth and creamy – it describes our vodka too it’s got a really nice finish to it,” he explained Grillo is certainly not the only one to be charmed by Puglia with the region becoming a highly popular tourist destination “The benefit to us of what is going on here in Puglia is the ability to broadcast that we exist to people outside of Puglia “You’ve got so many visitors here from all over the world We were sitting here [in the town of Ostuni] earlier and we could hear accents from Belgium the UK and the US – Puglia really magnifies us experience the vodka as part of their vacation As for the international markets Altamura Vodka is currently available in he said: “We’re in India and the UK The good thing about vodka is it is the ‘little black cocktail dress’ of spirits It is consumed almost everywhere and can be easily adopted.” “Brand Italy sells really well in Asia,” Grillo pointed out “Italian products are regarded as high quality and given the provenance of Altamura wheat that authenticity really helps us in markets that like Italian products.” It might be suggested that the sanctions against Russia in many western countries in response to the invasion of Ukraine might be advantageous for a new vodka brand looking to gain traction Grillo pointed out: “We slot right against Belvedere and Grey Goose and there isn’t really a Russian product in that category It’s those brand that own what I like to call the ‘€15 Martini market’.” the simplicity of a “proper Martini” is the perfect way to serve the spirit: “I’m a bit of a zealot about this – a 1940s three-to-one ratio with a really great Vermouth and If someone says they don’t like Martinis I tell them ‘you’ve never tasted a Martini what you’ve tasted is chilled vodka!’” Grillo also pointed out that Altamura Vodka has an umami character that works well with the olive brine of a Dirty Martini “We’ve also seen cocktails play on the idea of bread tomatoes and olive oil,” Grillo shared Grillo and EMEA president Steve Acuña suggested oysters sea urchin and any raw fish dishes as food pairings with “super-chilled” vodka But Altamura Distilleries is not stopping with using Pugliese wheat for vodka Grillo disclosed: “There will be two gins and one more geared towards a Negroni which has a little less juniper and more burnt orange aroma so that it works with the Campari and vermouth We will also produce what would be known in American parlance as a wheated ‘Bourbon’ and a wheated rye whiskey using 51% corn and 49% Altamura wheat and 51% rye and 49% Altamura wheat Matured in charred new oak for four-to-five years we’ll have to come up with the ‘Méthode Traditionnelle’ of Bourbon!” We met the co‐founder of Italy’s Altamura Vodka just six months ago we caught up with Frank Grillo again to discover the latest from the brand How have things been going since we last spoke but we didn’t really get going/start selling anything until that September/October and we’ve focused on introducing our product to the best bars and mixologists in the world Our initial focus has been Italy, and we’ve collaborated with cool venues like the St Regis Hotel in Venice and the Four Seasons in Florence. We really began our expansion in the late second half of 2023 – we’ve launched in the UK and we’re adding countries in Europe; France We’ve also entered Australia. We’ve collaborated with the Maybe Sammy team in Sydney, and will use their Sammy Fest (a big event in April) to properly launch there. We’ve got Salvatore [Calabrese] and Federico [Pavan] from Donovan Bar in London coming over. Salvatore has become a little bit like our launch machine, in a way. He also helped us launch in India at Sidecar Then there are one or two countries in South America What challenges have you faced since the initial launch I always say the easiest thing we do is make vodka – putting it in boxes and shipping is a royal pain Everyone’s got different rules on bottling The customs process and all of that has been a whirlwind to learn as we’ve expanded How is the new gin coming along and that’s really been all‐consuming for us We produced a neutral grain spirit from our wheat but we had to divert it to vodka because suddenly we were producing more of that than we planned But we want to produce the gin in smaller quantities but we thought that using the same mouthfeel that wheat gives the vodka would be very interesting We will get to the gin before the end of the year and it would have been a distraction to get the gin going We’re going to follow the standard of a Bourbon we can’t call it a Bourbon because it’s not made in the US but it will stylistically be a wheated Bourbon We want to express the wheat in every way we can we get the first production of the whisky in this year and as the EU maturing time is a minimum of three years it’s probably then four years before we release it as a wheated Bourbon doesn’t need as much of the impact from the wood as something that’s got a lot of rye in it and I would love to rack those here in Altamura We’ve identified a farmhouse we can lease and put the barrels there How are you positioning Altamura’s brand image in the vodka market We’re positioning the product against Grey Goose and Belvedere – that’s our competition but we just have a different take on vodka than they do We’re trying to represent the terroir of Altamura in the bottle This story is part of Loved and Lost, a statewide media collaboration working to celebrate the life of every New Jersey resident who died of COVID-19. To learn more and submit a loved one's name to be profiled, visit lovedandlostnj.com A renowned teacher and guidance counselor in Bergenfield for four decades “He was a professional student,” said Helen Altamura “He loved to read and to learn.” Altamura was raised in Weehawken and went to high school at St Michael’s in Union City with his future wife The two married one week after he graduated from Seton Hall University. He earned a master’s degree in education from Seton Hall and another from William Paterson He put them to use in the Bergenfield school district Altamura spent 40 years working in Bergenfield as an English and social studies teacher guidance counselor and districtwide guidance coordinator. “You could just tell he loved his job,” said his daughter “That definitely inspired me — and my sister — to get into teaching.” But after his first year in Bergenfield he was forced into a roughly two-year leave of absence he trained as a medic at California’s Fort Irwin and spent about 10 months in Vietnam. “He never mentioned any regrets,” his wife said “He always said he learned a lot over there.” Loved and Lost: Jack Ferber was passionate about family, community and sports Loved and Lost: Emmanuel 'Manny' Carrillo, a family man with a megawatt smile Altamura spent his last 47 years in Saddle Brook he taught Sunday School to the young students at Saddle Brook’s St Philip the Apostle Roman Catholic Church after his children had gone through the program. He also continued to work for the Bergenfield district after retirement he helped guide the students who were freshmen when he retired through their senior year. He loved teaching,” Helen Altamura said “He couldn’t get enough of it.” Altamura often read and spent time with his family The annual family getaway to Wildwood was his favorite tradition one he adopted from his parents and passed down to his three children Everyone made it a priority to come down,” Mitchell said “He was everything you could ever want in a father.” a month after he was hospitalized for an infection in his artificial knee Vodka producer Altamura Distilleries has partnered with distributor Amistad Spirits to launch its flagship expression in India Altamura Vodka will make its debut in North India By the end of the first fiscal quarter of 2024, the brand plans to also be available in Maharashtra said: “Partnering with Altamura Distilleries is a significant milestone for Amistad Spirits We are proud to be entrusted with the exclusive distribution rights for their exceptional Altamura Vodka in North India.” To mark the brand’s entry into the Indian market the Italian vodka is planning an exclusive launch at Sidecar Calabrese will help to host an afternoon masterclass and evening bar takeover sharing Altamura’s signature cocktail – The Altamura Martini – with guests Additional drinks have also been created especially for the event general manager sales and distribution – Asia at Altamura Distilleries added: “Altamura Distilleries is not just introducing spirits; we are sharing the Italian heritage and legacy Our range will be a blend of tradition and innovation The vodka is thought to be the first spirit made entirely from ancient Altamura grains The three stripes on Altamura’s bottle reflect the colours of Puglia – yellow The lioness symbolises the strength and pride of Puglia Altamura Vodka has been bottled at 43% ABV in a partnership that looks like a great fit Australia’s Mike Altamura is one of boxing’s very best at managing the careers of fighters Altamura has a wealth of experience taking boxers from their debut to world championships and everything in between Altamura has a resume that boasts taking 10 fighters to world titles extensive experience in scouting multiple Olympics and he has worked with fighters and companies across an incredible 80 countries worldwide To say he’ll bring a strong skillset to Sweet Science MGT is an understatement led by CEO and Athlete Manager Katia Benal the firm has an impressive roster of fighters They have Top-5 world-ranked Caroline Veyre Altamura was excited to delve into this new chapter in his career I know Katia from years back and we have kept in touch I met her through a great fighter named Tammara Thibeault who was in Australia for the 2018 Gold Coast Games” Katia has put together a very formidable team and it’s so refreshing to see someone who battles and fights for their fighters Altamura has an outstanding reputation industry-wide for his ability to deftly move fighters His experience in working with everybody from 4-round Katia has achieved so much in a short time To see her out there pushing and battling every day to land her fighters their best opportunity “To have the opportunity to partner with someone like that - I’m blessed” The managing director of Italy’s Altamura Distilleries discusses how the company is using local wheat to create vodka Located in the Puglia region, Altamura Distilleries recently launched its vodka in the UK The wheat used to make the vodka has been grown in Altamura or the adjoining communes of Puglia in Italy for more than 2,000 years Grillo said: “The original thought about Altamura Vodka was if you boiled a loaf of bread Altamura Distilleries has sourced its wheat through the ‘godfather of grain’ Cappiello’s instinctive knowledge of his crop gave him the confidence to participate in the project: “If you can make the best bread in the world the spirit is distilled in Poland using a contract distiller but there are plans to open a gin and vodka distillery in Puglia Grillo explained: “Here [in Puglia] we’re going to first build out the gin distillery and then the vodka distillery We didn’t know what reception the product was going to get so we’ve started with a contract distiller to get set up We ship all the wheat from Altamura to Poland and then ship the vodka back to Italy.” The vodka is triple distilled and filtered five times through charcoal Altamura Vodka is currently available in India and the UK “The good thing about vodka is it is the ‘little black cocktail dress’ of spirits,” Grillo said “It is consumed almost everywhere and can be easily adopted Italian products are regarded as high quality that authenticity really helps us in markets that like Italian products.” Grillo pointed out: “We slot right against Belvedere and Grey Goose and there isn’t really a Russian product in that category It’s those brands that own what I like to call the ‘€15 Martini market’.” Grillo also recommends serving the vodka in a Martini: “I’m a bit of a zealot about this – a 1940s three-to-one ratio with a really great vermouth and He also pointed out that Altamura Vodka has an umami character that works well with the olive brine of a Dirty Martini Grillo disclosed: “There will be two gins; a London Dry which has a little less juniper and more burnt orange aroma so that it works with the Campari and vermouth “We will also produce what would be known in American parlance as a wheated ‘Bourbon’ and a wheated rye whisky Matured in charred new oak for four to five years we’ll have to come up with the ‘méthode traditionnelle’ of Bourbon.” We are using cookies to give you the best experience on our website. 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This means that every time you visit this website you will need to enable or disable cookies again. 06 Jan 2025 16:30:00 GMT?.css-1txiau5-AnswerContainer{color:var(--GlobalColorScheme-Text-secondaryText2);}Team Altamura won 2–0 over Foggia on Mon The current head to head record for the teams are Foggia 1 win(s) Have scored 5 goals in their last 5 matches Haven't kept a clean sheet in 9 matches Who won between Foggia and Team Altamura on Mon 06 Jan 2025 16:30:00 GMT?Team Altamura won 2–0 over Foggia on Mon 06 Jan 2025 16:30:00 GMT.InsightsHave scored 7 goals in their last 5 matches Foggia is playing home against Team Altamura on Mon NJ) -- Necessity is the mother of invention for DIY culture especially in the arts in NYC Altamura Legacy Concerts is excited to bring that spirit to its living room setting in the heart of Princeton on Sunday The gathering kicks off with pioneer break dancer Ana "Rokafella" Garcia in a talk and a viewing of excerpts from her film "All the Ladies Say." John Cage's prepared piano music follows with New York Times featured pianist Adam Tendler ALC Artistic Director Cristina Altamura hosts with Adam Sliwinski of Sō Percussion Princeton University piano student Otto Trueman will warm up the audience starting at 3:45pm Tickets range from $10-$30 and are available for purchase online Princeton United Methodist Church is located at 7 Vandeventer Avenue ((at the corner of Nassau Street) in Princeton Legacy Arts International is a Princeton NJ based musical arts organization which facilitates cultural exchange initiates performances and educational programs to build vibrant artistic communities and documents important artistic legacies This series was also developed to serve the PUMC community and helps to fulfill its core mission to provide a physical space that is gracious the sanctuary area of the venue will be available for a free will offering at the door to increase accessibility thanks to Legacy Arts International donors and the generosity of my dear friends and family 2022 /PRNewswire/ -- Altamura Distilleries a producer of premium spirits from the unique Altamura Italian wheat won four top awards from The Spirits Business' Vodka Masters Competition and has named the companies' first UK distributor Altamura Distilleries' Vodka won the following awards in The Spirits Business' Vodka Masters Competition: Category Vodka – Smooth Vodka – Europe Super-Premium (£21-£30) Vodka – Wheat "Our mission was to make a premium vodka that represents the terroir of Altamura and its storied wheat," stated Frank Grillo "We're very pleased the tasters recognized the uniqueness of our product This is the second judging we have entered since launching our vodka and the second time we have been recognized with an award." Altamura Distilleries is also very pleased to announce that it has teamed with Saviano Food Import LTD West Yorkshire to distribute the companies' vodka and soon to be available gin in northern England "We are excited to be able to bring this uniquely Italian vodka to our customers," said Gennaro Saviano of Saviano Foods "We are certain the barmen at our client restaurants will enjoy using Altamura Vodka to create unique cocktails for their patrons." Saviano Food Import, with more than 10 years experience, provides a multitude of Italian foods, produce, wines and spirits to top Italian restaurants throughout Yorkshire, Lincolnshire, Manchester and Liverpool. For more information: http://www.savianofoodimportltd.com/ Altamura Distilleries Media Contact:Scott Hamilton+1 601-214-1133[email protected] Do not sell or share my personal information: IFLScience HomeHow The Ancient "Altamura Man" Became Embedded In A Cave WallComplete the form below to listen to the audio version of this article FacebookemailJames is a published author with four pop-history and science books to his name. He specializes in history, strange science, and anything out of the ordinary. FacebookemailDOWNLOAD PDF VERSION The "popcorn" appearance is the easiest part to explain Image credit: Riga et al, PLOS ONE, 2020 (CC BY 4.0) - cropped a strange sight was found in a cave in Altamura Inside the Lamalunga cave – created by a sinkhole – was a virtually complete fossilized skeleton of a human As well as that, the remains were covered with "cave popcorn"; tiny, spot-like marks all over the bones. The "popcorn" appearance could be explained easily. When calcite is dissolved in rainwater it can then accumulate on the surface of the cave floor "Cave popcorn usually occurs in wet areas of the cave where water can flow on the surface," Lee-Gray Boze, physical scientist from the United States Geological Survey, told How Stuff Works "Many of the longest cave systems tend to be drier and these dry areas tend to be less decorated usually indicating a wet environment and air flow." "Other common environments can include dripping water in which the drips may cause popcorn to form in a radius around the drip sites." Image credit: Riga et al., PLOS ONE, 2020 (CC BY 4.0)The popcorn helped one team discover the likely cause of the man's death. "Faunal remains found in some of the galleries are often isolated bony elements accumulated in depressed areas of the cave, suggesting that they were transported and dispersed by water," one team investigating the body found "This was not the case with the human skeleton given that it is largely represented and concentrated in a small area the skeleton collapsed where it has been found." The team believe that the man had probably fallen into a sinkhole, and gotten stuck. There he likely starved or died of dehydration before being covered in popcorn and discovered by scientists over 100,000 years later Altamura man still had a few surprises left Further analysis of the man's teeth by another team in 2020 found wear on the teeth suggesting that he was an adult – though not old – at the time of his unfortunate death They also found that one of his teeth was likely lost a few weeks before his death "since the other teeth of the right maxillary arcade had enough time to rearrange their position along the tooth row" "must have been lost a few weeks before death since alveolar resorption is still in an incipient stage". An earlier version of this article was published in May 2023