Vannes’ quest to avoid relegation from the Top 14 will take place without Juan Bautista Pedemonte. The Pumas flanker is out for the remainder of the season. He underwent knee surgery in January. The operation was thought to see him sidelined for up to three months; however, it will be for the duration of the season ESPN Argentina report that Pedemonte has also had surgery on a troubled shoulder His recovery time means Vannes will be without him After 16 rounds of the 2024-2025 Top 14 season Vannes are bottom of the table on 24 points Racing 92 are 13th on 27 and Stade Français and 12th on 28 points Tags A crushing 78-18 away win by Los Pampas sees the Buenos Aires side returning to … Enter your email to receive editorial updates, special offers and breaking news alerts from Vogue Business. You can unsubscribe at any time. Please see our privacy policy for more information LVMH is boosting its jewellery production capacity with the acquisition of the Pedemonte Group a manufacturer with locations in northern Italy and Paris Pedemonte Group was founded in 2020 as a merger of several independent production workshops known for their use of technology and traditional craftsmanship and currently has 350 artisans and employees the company has its own Made in Italy jewellery brand LVMH bought Pedemonte Group from the Equinox III SLP SIF investment fund for an undisclosed sum “With this strategic acquisition for our maisons the LVMH Group further strengthens its presence in Italy while continuing to support the ecosystem of companies that contribute to the success of our maisons,” says Toni Belloni our maisons will gain a partner recognised for its know-how to support their growth and maintain their leadership in jewellery.”  Earlier this year, LVMH expanded its Métiers d’Excellence artisan training programme to the US in partnership with Tiffany in an ongoing effort to preserve centuries-old skills Comments, questions or feedback? Email us at feedback@voguebusiness.com Luxury braces as China hits new Covid record Can Black Friday solve fashion’s stock problem? Sephora appoints new president and CEO Sign up to our newsletter for a truly global perspective on the fashion industry The players are Gloucester second-rower Matías Alemanno and Vannes flanker Juan Bautista Pedemonte Both now face a significant time on the sidelines before they will play again Santiago del Estero’s Juan Bautista Pedemonte is facing two or three months on the sidelines Pedemonte underwent surgery on his meniscus including the cleaning of the area He has had limited game time in Vannes’ rookie Top 14 season; thus far Pedemonte has made four appearances Pedemonte made his test debut in 2024 for Argentina he will be back playing in time to be considered for international duty in July Tags LVMH Acquires Jewelry Manufacturer Pedemonte Group The strategic acquisition will bolster the luxury titan’s production capacity in its watch and jewelry division. 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Supplier BulletinApr 24, 2025Protect Your Customers and Your BusinessSponsored by the Gemological Institute of America This site uses cookies to give you the best online experience. By continuing to use & browse this site, we assume you agree to our Privacy Policy All measures were dependent on anesthesia stages. BIS, LZc, and PE presented lower values at increasing anesthetic dosage. Inversely, Alpha Power increased with increasing propofol at low doses, however this relation was reversed at greater effect-site propofol concentrations. Significant group differences between elderly patients (>65 years) and young patients were observed for BIS, Alpha Power, and LZc, but not for PE. BIS, Alpha Power, and LZc show important age-related biases during slow propofol induction. These should be considered when interpreting and designing EEG monitors for clinical settings. Interestingly, PE did not present significant age differences, which makes it a promising candidate as an age-independent measure of hypnotic depth to be used in future monitor development. Volume 14 - 2022 | https://doi.org/10.3389/fnagi.2022.910886 Background: Improving anesthesia administration for elderly population is of particular importance because they undergo considerably more surgical procedures and are at the most risk of suffering from anesthesia-related complications Intraoperative brain monitors electroencephalogram (EEG) have proved useful in the general population Probably because these monitors do not account for the natural differences in EEG signals between young and older patients In this study we attempted to systematically characterize the age-dependence of different EEG measures of anesthesia hypnosis Methods: We recorded EEG from 30 patients with a wide age range (19–99 years old) and analyzed four different proposed indexes of depth of hypnosis before during and after loss of behavioral response due to slow propofol infusion during anesthetic induction Alpha Power and two entropy-related EEG measures and permutation entropy (PE) using mixed-effect analysis of variances (ANOVAs) We evaluated their possible age biases and their trajectories during propofol induction Results: All measures were dependent on anesthesia stages and PE presented lower values at increasing anesthetic dosage Alpha Power increased with increasing propofol at low doses however this relation was reversed at greater effect-site propofol concentrations Significant group differences between elderly patients (>65 years) and young patients were observed for BIS and LZc show important age-related biases during slow propofol induction These should be considered when interpreting and designing EEG monitors for clinical settings PE did not present significant age differences which makes it a promising candidate as an age-independent measure of hypnotic depth to be used in future monitor development In this context we believe it is paramount to (1) better characterize this bias to account for it in clinical settings and (2) explore the age-dependence of other candidate measures of hypnotic depth PE also shows greater values during wakefulness than after LOC it remains unknown whether these measures showcase important age biases or if they are independent of the patient’s age In this study we attempted to systematically characterize the age-dependence of two spectral-based EEG markers of depth of anesthesia and to explore the possible age-dependences of two information-based EEG markers of hypnosis We did this by analyzing EEG signals from before during and after LOC in patients of a wide age range undergoing surgical anesthesia by slow propofol infusion This study is reported following the STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) guidelines and was registered in Clinical Trials.gov (NCT04774120) Local ethics committee approvals (Comité de Ética de Ciencias de la Salud Pontificia Universidad Católica de Chile) were obtained before data acquisition This was a prospective cohort study conducted at the Hospital Clínico Pontificia Universidad Católica de Chile (Santiago Patient recruitment and informed consent were obtained during preoperative visit Data was collected from anesthesia preoperative assessment intraoperative electronic health records and postoperative evaluation Patient follow-up period was up to discharge from the post-anesthesia care unit The start of non-zero suppression rate (yes or no) was defined as the moment when a suppression rate value [suppression rate (SR) >1%] appeared in the BIS® monitor Eligibility criteria included patients aged >18 years scheduled to undergo elective surgery under general anesthesia presenting an American Society of Anesthesiologists (ASA) Physical Status I or II Patients with preexisting neurocognitive comorbidities body mass index greater than 35 kg m–2 or altered preoperative cognitive status (Mini-mental test <24 points) were excluded Patients were selected from the elective surgeries schedule according to research and surgical team availability they were invited to participate during preoperative evaluation SedLine and BIS data were simultaneously obtained in the operating room and pulse oximetry) were connected to the patients and a 20G peripheral venous catheter was installed for fluid and drug administration Patients received 100% oxygen for 3 min prior to propofol infusion we administered propofol at a rate of 15 mg kg–1 h–1 in patients ≥65 years and 20–25 mg kg–1 h–1 in younger patients (<65 years) until a SR ≥1% was observed in the BIS monitor If SR ≥ 1% was not achieved during the first 10 min after the start of propofol administration the infusion rate was increased by 5 mg kg–1 h–1 Propofol infusion was stopped at SR ≥ 1% and the study protocol was considered completed at this point opioids and muscle relaxants were administered To estimate Alpha Power, we followed previously employed strategies (Şeker and Özerdem, 2016) For each 15 s segment we filtered the signal between 8 and 12 Hz (Butterworth filter fourth order) and calculated its Hilbert transform (analytical signal) The square of the absolute value of the analytic signal yielded the spectral power within the alpha band which we averaged across time for each 15 s segment Permutation entropy was calculated using the “ordpy” Python library (Pessa and Ribeiro, 2021) with an embedding dimension (m) of 5 points and an embedding delay of 1. These values were chosen to follow previously published guidelines (Pessa and Ribeiro, 2021). Details of this measure can be found in previous work (Olofsen et al., 2008) PE segments the signal into groups of m contiguous points (embedding dimension and codifies the points in terms of its ordinal pattern if the 5 points sub-segment is strictly decreasing 5}; if it strictly increases it will be coded as {5 1}; if it decreases in the first 4 points but the last one increases above all of them it will be coded as {2 This is repeated for all sub-segments in the signal each 15 s segment produces a high number of patterns Permutation entropy is the Shannon entropy of this distribution of all these ordinal patterns Shannon entropy (and PE) will be maximal for a homogeneous distribution that is a signal in which all ordinal patterns occur with the same probability Shannon entropy (PE) will be low if only a few of the possible ordinal patterns are present in the signal were averaged to obtain one value per patient per minute for each measure (PE to estimate Total Spectral Power and Spectral Edge Frequency 95% (SEF95) we calculated the power of each frequency component in each patient using the DFT-Welch method with hanning windows (4.5 s 50% overlap) within the 15 s raw EEG windows Total Alpha Power was defined as the summation of all spectral powers lower than 30 Hz We chose this limit as our sampling frequency because it did not allow us for robust spectral estimation in higher frequencies SEF95 was calculated from the cumulative sum of spectral powers across frequencies as the frequency value below which 95% of the spectral power was contained Considering a previous study reported by Lysakowski et al. (2009) would have 80% power to detect a difference of 15 units of BIS in the group’s averages employing a within group standard deviations of 12 BIS units with a significance level of 0.05 using a two-sided two-sample t-test Differences in demographic and clinical data were assessed using Independent Samples t-test (uncorrected, see Table 1) Normality was checked with the Shapiro–Wilk test To analyze the effect of age on each EEG measure in different anesthetic stages we separated our data into five 1-min segments: 2 min before LOC (LOC-2) the midpoint between LOC and the maximal propofol concentration at the effect-site accordingly to Schnider’s model (LOC-CeMax) and the point of maximal effect-site concentration (CeMax) we conducted a t-test to compare each measure at LOC between groups (above or below 65 years of age) and PE) we conducted a mixed-effect analysis of variance (ANOVA) with age group as the between subjects’ factor and anesthesia stage (LOC-2 The assumptions of sphericity of the variances were tested using Mauchly The Huynh-Feldt correction was applied if there was violation to the sphericity assumption We recruited a total of 30 patients ranging from 19 to 86 years of age that underwent urological or gastrointestinal surgery (Table 1), separated into two groups, Young (<65, median [IQR]: 44[26.5]) and Elderly patients (>65, 71.5[9.5]). Modeled effect-site propofol concentrations were similar between groups before and during LOC and deviated strongly in latter anesthetic stages (Table 2 and Figure 1) Schnider’s Effect-site propofol concentrations across anesthesia stages: 2 min before loss of consciousness (LOC) (LOC-2) for elderly (unfilled circles) and young patients (filled circles) Error bars represent the 95% confidence interval Interestingly PE was not significantly different between young and elderly patients [PE F(1) = 0.216 and as expected elderly patients showcased significantly lower total spectral power and higher SEF95 than younger populations and permutation entropy (PE) across anesthesia stages and age groups Line plots depicting the different values of BIS (A) and PE (D) across anesthesia stages for young (filled circles) and elderly (empty circles) patients: Error bars represent the 95% confidence interval Hypnotic measures at loss of consciousness (LOC) In the present work we systematically analyzed the age differences of four different EEG-derived measures of hypnotic depth before during and after loss of consciousness by continuous propofol infusion and LZc displayed a significant difference between age groups throughout anesthesia stages Elderly patients showed significantly greater BIS and LZc values and significantly lower Alpha Power PE did not show significant differences associated with age if BIS is employed in surgical settings on elder patients it should not be interpreted in the same way as it is interpreted in younger populations (e.g. they quantify very different aspects of a signal PE quantifies the diversity (entropy) of very small ordinal patterns of activity; in this work those patterns lasted ∼56 ms LZc also qualifies the diversity of patterns then only patterns that are strictly non-redundant between them are selected these are in general much longer than those considered in PE calculations The differences in the age-dependency of these two measures reported here could inform further research into the specific aspects of anesthesia EEG signals that change during aging The dosing scheme used reflects clinical practice whereby elderly patients receive less propofol than younger patients at LOC in combination with the fact that BIS and LZc showcased higher values in elderly patients could imply that these measures are more closely related to predicted effect-site propofol concentrations than to depth of anesthesia however this should be tested specifically in a separate study our results showcase the presence and magnitude of the age bias of currently employed EEG derived hypnotic depth measures (BIS and Alpha band power) throughout five different induction stages We also show that LZc also presents strong age biases during propofol induction these biases do not preclude the use of any of these indexes as measures of depth of hypnosis but encourage the inclusion of age as a covariable when using them to estimate depth of hypnosis in clinical settings PE appears as a promising candidate to be considered as an age-independent measure of hypnotic depth The data is available upon reasonable request from the corresponding author The studies involving human participants were reviewed and approved by Comité de Ética de Ciencias de la Salud Pontificia Universidad Católica de Chile The patients/participants provided their written informed consent to participate in this study and LC: interpretation of results and drafting of the manuscript All authors contributed to the article and approved the submitted version Funding for this project came from institutional and departmental sources the FONDECYT postdoctoral project (N°3200248) awarded to GB We would like to thank Victor Contreras for helping with data acquisition and administrative endeavors The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher The Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fnagi.2022.910886/full#supplementary-material Occurrence of and risk factors for electroencephalogram burst suppression during propofol-remifentanil anaesthesia Brain activity complexity has a nonlinear relation to the level of propofol sedation CrossRef Full Text | Google Scholar Sample entropy tracks changes in electroencephalogram power spectrum with sleep state and aging CrossRef Full Text | Google Scholar Pharmacokinetic-pharmacodynamic model for propofol for broad application in anaesthesia and sedation BIS monitoring on intraoperative awareness: A meta-analysis Effect of delirium and other major 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the anteriorization of alpha rhythms during propofol-induced unconsciousness Age-related changes in 1/f Neural electrophysiological noise Comparison of bispectral index-guided individualized anesthesia with standard general anesthesia on inadequate emergence and postoperative delirium in elderly patients undergoing esophagectomy: A retrospective study at a single center EEG complexity as a measure of depth of anesthesia for patients CrossRef Full Text | Google Scholar Bispectral index monitoring does not improve early recovery of geriatric outpatients undergoing brief surgical procedures Fuentes C and Cortinez LI (2022) The effect of age on electroencephalogram measures of anesthesia hypnosis: A comparison of BIS Lempel-Ziv complexity and permutation entropy during propofol induction Copyright © 2022 Biggs, Boncompte, Pedemonte, Fuentes and Cortinez. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) distribution or reproduction in other forums is permitted provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited in accordance with accepted academic practice distribution or reproduction is permitted which does not comply with these terms *Correspondence: Juan C. Pedemonte, amNwZWRlbW9AZ21haWwuY29t Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher 94% of researchers rate our articles as excellent or goodLearn more about the work of our research integrity team to safeguard the quality of each article we publish By subscribing, you agree to our Terms of Use and Privacy Policy Pedemonte’s Watches & Jewelry Division as well as its jewelry maisons will allow LVMH to significantly increase its production capacity while its workshops will contribute to the overall growth of the division Pedemonte group was first established in 2020 under Equinox through a merger of several independent production workshops including Villa Pedemonte Atelier and Vendorafa Lombardi combining decades of heritage and experience The exact figure of the acquisition from Equinox III SLP SIF investment fund has yet to be disclosed Merging “cutting-edge technology and artisanal craftsmanship,” Piedemonte’s impressive execution in its collaboration with LVMH maisons ultimately warranted the deal Metrics details Despite a high rate of concurrent mathematical difficulties among children with dyslexia we still have limited information regarding the prevalence and severity of mathematical deficits in this population we developed a comprehensive battery of cognitive tests known as the UCSF Mathematical Cognition Battery (MCB) with the aim of identifying deficits in four distinct mathematical domains: number processing The mathematical abilities of a cohort of 75 children referred to the UCSF Dyslexia Center with a diagnosis of dyslexia along with 18 typically developing controls aged 7 to 16 were initially evaluated using a behavioral neurology approach A team of professional clinicians classified the 75 children with dyslexia into five groups based on parents’ and teachers’ reported symptoms and clinical history These groups included children with no mathematical deficits and children with mathematical deficits in number processing the children underwent evaluation using the MCB to determine concordance with the clinicians’ impressions neuropsychological and cognitive standardized tests were administered Our study reveals that within a cohort of children with dyslexia and among those with mathematical deficits there is heterogeneity in the nature of these deficits If these findings are confirmed in larger samples they can potentially pave the way for new diagnostic approaches Understanding the nature of mathematical deficits in children with dyslexia is essential for designing appropriate interventions and elucidating the complex relationship between reading and mathematical abilities we designed and tested a new battery of tests the UCSF Mathematical Cognition Battery (MCB) specifically designed to comprehensively assess mathematical deficits in a cohort of dyslexic children The development of the MCB is rooted in the extensive body of cognitive and neuroscientific research we provide a comprehensive description of this research and elucidate its influence in shaping the selection of the four mathematical domains evaluated by the MCB: 1 These domains encompass number processing; arithmetical procedures; arithmetic facts retrieval; and geometrical abilities which affect mathematical cognition and differ in their cognitive and neural correlates can be differentially impacted by neurological processes and environmental factors they likely contribute to the classification of mathematical deficits The brain network involved in number processing primarily encompasses the lateral parietal lobe but also extends to the inferior frontal gyri, insula, and subcortical structures44 With such an extensive network of brain regions problems in mathematical reasoning can stem from various underlying computations leading to different behavioral phenotypes clinical assessment of deficits in number processing should include subitizing non-symbolic ANS (comparison between two arrays of dots) symbolic ANS (comparison between two numbers written in digit form) and transcribing between number digits and number words When assessing calculation arithmetical procedures skills clinically it is important to cover mental calculations as well as written calculations involving all four operations Children who struggle with arithmetic facts often face difficulties in memorizing basic addition and subtraction facts (e.g. 3–1 = 2) or recalling multiplication tables (e.g. if their number processing and arithmetical procedures skills remain intact they may be able to reconstruct operation results using counting and mental strategies When conducting clinical assessments of arithmetic facts retrieval it is crucial to evaluate an individual’s knowledge of these facts The testing should include appropriate assessments of multiplication tables taking into account the individual’s age and educational level Drawing from research in mathematical cognition and neuroscience which supports the potential classification of four distinct mathematical deficits we have developed and evaluated a new battery of tests called the UCSF MCB The MCB is specifically designed to comprehensively assess the four previously mentioned mathematical domains: 1 we provide a detailed description of the battery and present the results obtained from a large cohort of children (n = 75) referred to the UCSF Dyslexia Center with a dyslexia diagnosis as well as 18 typically developing control children Our focus is on classifying mathematical cognitive deficits in children with dyslexia There were no group differences noted in the demographic characteristics there was a significant group difference in diagnoses when the controls were removed from the analysis the significant group difference in diagnoses was no longer present (p = 0.318) No significant differences were found in the distribution of mathematical deficits across grades (p = 0.83) it should be noted that this analysis may be underpowered due to the relatively low number of cases in some groups The TD group performed significantly better than all other subgroups on the ANS for digits It is possible that the Dysl_notM group performed worse than the TD group in this subtest because 20% of the Dysl_notM group had ADHD and attentional deficits may affect the ANS score performance on the subitizing subtest revealed a main effect of group (p = 0.031) but post hoc analysis indicated a specific group effect only for TD compared to all other groups combined (TD mode = 6 dots; all other groups combined mode = 5; p = 0.016) The Dysl_notM group performed well on the MCB subtests evaluating number processing Some of these participants obtained low scores only on subtests assessing teaching exposure (e.g. 8% obtained a low score in the “equivalent fractions” subtest and 18% in the “percentage” subtest) or more complex mathematical skills (e.g. 30% obtained a low score in the “simplifying expressions” subtest and 36% obtained a low score in the “solving equations” subtest) Lexical mistakes refer to instances when digits are incorrectly chosen Syntactical mistakes refer to instances when digits are correctly chosen Children with deficits in number processing performed significantly lower than all other groups in the addition and subtraction subtests of the calculations section and the multiplication subtest of the arithmetic facts section which suggests that deficits in number processing represent more fundamental deficits in learning mathematics They also performed worse than TD and Dysl_notM subgroups on the ANS for digits They correctly identified the pattern in each sequence but made mistakes in calculating the answer the arithmetical procedures group exhibited comparable performance to children with number processing deficits they did not demonstrate strong performance in the number processing subtests their scores in these particular subtests were still relatively higher than those of the number processing group the group showing deficits in arithmetical procedures performed better on most subtests than the group showing deficits in number processing but worse than the other subgroups They also took the longest to complete the written calculation subtest which also includes multiplication and division they performed not significantly different from the group with deficits in number processing on both computerized geometrical subtest and the 3D models subtest The group with deficits in geometrical abilities was the only group to perform worse than TD on the ANS for dots (p = 0.032) which might be confusing for children who have trouble perceiving forms and identifying shapes Three participants (4% of dyslexia sample) were excluded from further analyses because their deficits overlapped in arithmetic procedures and fact retrieval and a clear subgroup could not be determined their previous and current history did not indicate any symptoms of mathematical difficulty ~25% of the children with dyslexia and mathematics difficulties (12 out of 47) obtained a score on the WJ-IV Calculation test at or greater than the 25th percentile (average performance); of these children five had deficits on arithmetic facts retrieval the group with Dysl_notM had higher scores on the WJ Calc and Matrix Reasoning subtests than the groups showing deficits in number processing and arithmetical procedures but the Dysl_notM and the group with a deficit in arithmetic facts retrieval performed better than the group with a deficit in number processing They also had significantly lower scores on JLO than the arithmetic fact retrieval group (p < 0.05 Bonferroni-corrected) Most deficits appeared in tests that require visual reasoning and judgments Children with deficits in arithmetical procedures obtained lower scores than the Dysl_notM group on WJ Calc and Matrix Reasoning Children with deficits in arithmetic facts retrieval did not perform worse than other groups in any of the neuropsychological tests They had the highest group average of the dyslexia sample on untimed line degree matching (JLO) and performed significantly better than the children with deficits in number processing The children with deficits in arithmetic facts retrieval also had the highest scores on geometry subtests of the MCB among the groups with math difficulties Children with deficits in geometry obtained good scores in general cognitive and academic tests their scores on the visuomotor test (Beery VMI) were the lowest They also had a low score in long-term visual recall (Rey-Osterrieth Figure 3-minute Delay) our understanding of the frequency and severity of these deficits in this population remains limited we have developed and evaluated the UCSF MCB a set of subtests specifically designed to classify mathematical cognitive deficits in children with dyslexia The MCB was developed at UCSF Dyslexia Center (UCSF-DC) and tailored for children ranging from 2nd to 8th grade allowing for personalized educational practices and interventions based on individual profiles we present the initial results of a large cohort of children referred with a diagnosis of dyslexia (n = 75) who were carefully evaluated by a group of expert clinicians The MCB confirmed the clinicians’ mathematical impressions demonstrating its potential as a promising assessment tool that can be scaled to larger cohorts of children we explore the clinical and educational implications of our findings and their relationship to current neurocognitive theories of mathematical deficits The main result of our study is that the MCB can effectively identify mathematical impairments in children with dyslexia 50 out of the 75 participants referred with a diagnosis of dyslexia at the UCSF-DC were found to have deficits in mathematics which were rarely identified in their previous evaluations This suggests that many cases of mathematical difficulties are currently going undetected The commonly administered assessments such as WJ (Calculation Test and FAM may not capture difficulties in mathematics particularly if those difficulties are not severe or related to number deficits the arithmetical procedures group and the arithmetic facts group did not show significantly poorer performance in their corresponding subtests It is worth noting that the number processing group displayed inferior performance across the subtests related to arithmetical procedures and arithmetic facts retrieval the arithmetic facts retrieval group exhibited the lowest scores in the subtests designed to identify challenges in arithmetic facts retrieval the arithmetical procedures group demonstrated the lowest scores in the subtests designed to pinpoint difficulties in calculation We will briefly explore potential criteria to describe the main characteristics of each group and the likely neurocognitive correlates Deficits in number processing are characterized by difficulties in understanding and manipulating numerical quantities Children with deficits in number processing struggle with comprehending the magnitude of numbers deficits in number processing were observed in at least three of the following subtests: translating numbers between different representations (digits Sometimes deficits may also be observed in subitizing and more frequently in the Approximate Number System (ANS) both in symbolic (digits) and non-symbolic (dots) formats We found no significant difference in the group of children with a number processing deficit compared to the other groups in the subitizing test these children often struggled to provide an accurate estimation of the number of dots when the quantity exceeded five even when the maximum number of dots on the screen was nine children with a deficit in number processing performed worse than the control group and the other subgroups on the ANS for digits While all groups tended to perform better on digits than dots the children with a deficit in number processing only showed a slight improvement in digits compared to dots (a difference of one point) whereas the other groups showed greater differences (minimum difference: 6 This further highlights the pervasive difficulties experienced by children with a deficit in number processing no significant difference was observed between children with a deficit in number processing and children with a deficit in geometrical abilities in the geometrical subtests children with a deficit in number processing demonstrated difficulties in various tests that require visual reasoning and judgment but showed preserved verbal knowledge This suggests that a cognitive mechanism involving higher-order nonverbal reasoning and attention may underlie the difficulties observed in this subgroup Children with deficits in number processing often exhibit this difficulty through mistakes in counting and identifying patterns in numerical sequences only 13.3% (10 out of 75) of the children with dyslexia were diagnosed with deficits in number processing This indicates that only a small portion of dyslexic children who struggle in mathematics may also have dyscalculia Deficits in arithmetical procedures are characterized by a focal impairment when applying arithmetic procedures While not showing deficits in numerical skills children with deficits in arithmetical procedures struggle with understanding and reproducing mental and/or written calculations these children performed significantly differently from the other subgroups both in terms of accuracy and speed in calculations Errors include treating subtraction as a commutative operation (e.g. 5–3 ≠ 3–5) and inverting the order of digits (e.g. Slow processing was often due to the adoption of ineffective counting strategies this group did not demonstrate a significant difference in performance compared to the number subgroup making it challenging to precisely characterize their mathematical deficits It is possible that they share similarities with the number subgroup it is more likely that their difficulties stem from cognitive mechanisms unrelated to the mathematical domain indicating that other factors might contribute to their challenges “subtract the smaller number from the larger,” at the expense of other rules which may suggest difficulties in ranking competing choices It is also possible that when performing written calculations If someone has proficient calculation skills and knowledge they may divide their attention between the motor program of writing and the estimation of the correct result in order to check their work simultaneously a child who has not mastered calculations may instead divide their attention between the motor program of writing and searching their mind for the appropriate calculation rules/algorithms for those numbers interventions for this type of deficit may focus on alternate strategies that reduce the burden of divided attention Deficits in arithmetic facts are characterized by impairments in arithmetic facts retrieval Children with deficits in arithmetic facts do not show difficulties in number subtests they struggle to recall the results of operations that should have been learned through rote memorization The deficit in recalling multiplication tables is coupled with difficulties in writing multi-step multiplications and divisions Since our cohort was recruited based on symptoms of dyslexia it is difficult for us to distinguish these differences Future studies using the MCB to evaluate the performance of children with dyslexia compared to dyscalculia could help address this question Deficits in geometry are characterized by impairments in geometrical abilities Children with deficits in geometry exhibit difficulties in the nonverbal representations of mathematical information They may struggle to process distances and directions recognize geometrical transformations (e.g. and mentally reconstruct a 3D model from a 2D shape they made mistakes in solving problems related to geometrical transformations (symmetries and identifying characteristics of geometrical figures Recent research suggests that spatial ability predicts performance in mathematics100 but it remains unclear which mathematical skills are involved Our group of children with deficits in geometry is not large enough to draw conclusions on this point and further research is necessary to validate our findings The existing research examining the relationship between dyslexia and mathematical impairments is limited and still underdeveloped has accepted the existence of different subtypes of dyslexia This raises the possibility of subtyping difficulties in mathematics as well but further studies might aim at disentailing the specific neural correlates associated with visuo-perceptual The emerging line of research indicates that mathematical impairments may exhibit different profiles and underlying mechanisms similar to the subtypes observed in dyslexia Other subtests appear to simply differentiate typically developing children from children with dyslexia but do not provide information on the specific deficits (subitizing and ANS for digits) suggesting that deficits in number processing might be subdivided into two distinct groups Given the developmental nature of learning difficulties related to mathematics it is possible that mathematical deficits may present differently at different ages and/or be partially compensated through other cognitive strengths such that one may only show difficulty when math reasoning becomes more complex and the learning environment is less scaffolded future work should be careful to include skill assessments at varying points of development through adulthood future studies might help to elucidate the unique cognitive and neural correlates of these mixed cases the cohort of children we tested (n = 93) is relatively small and unequal in group size preventing more advanced statistical comparisons of the distinct mathematical deficits It would be helpful to replicate these findings in larger studies and with reliability metrics for the MCB Despite recognizing the limitations in our approach we believe that the MCB provides a foundation for clinically relevant and neurocognitively informed diagnoses and models we are still in the development stage of the battery in which we are relying on detailed clinical observation to determine relevant subtests following a behavioral neurology methodological approach We are currently administering a second version of the MCB to increase our sample size with an independent group of subjects which will allow us to conduct refined psychometric standardization and to identify cut-off scores for each group We plan to use the MCB to assess children who only have mathematical learning differences to investigate whether the four deficits align with subtypes of dyscalculia Four subtests were specifically created to assess arithmetical procedures skills with three focusing on mental calculation skills and the fourth evaluating written calculation abilities The addition and subtraction problems within the calculation subtests were designed to target difficulties related to arithmetic procedures while a mental multiplication subtest and the multiplication and division problems in the written calculation subtest aimed to evaluate arithmetic facts retrieval skills the time taken to complete the calculation subtests was recorded to assess fluency which can help differentiate between difficulties in arithmetic procedures and arithmetic facts retrieval These tasks involved items that varied in terms of symmetry three tasks were added to evaluate mathematical abilities in older children in order to detect instances when individuals might have compensated for basic deficits but still experience difficulties with more complex problems seven supplementary tasks were designed to verify adequate teaching exposure and to confirm or exclude specific deficits a deficit in arithmetical procedures could be confirmed when solving word problems if the appropriate operation is identified but the calculation is performed incorrectly Participants were recruited through the UCSF-DC a multidisciplinary research center dedicated to studying dyslexia and related neurodevelopmental cognitive disorders participants who were referred due to concerns of dyslexia underwent a comprehensive research evaluation conducted by a team of clinicians This team provided an overall diagnostic impression based on various factors including clinical history (first symptoms and most severe impairments reported by parents and teachers) family history (similarities between siblings and/or parents) standard neuropsychological and academic testing and questionnaire responses indicating clinical significance Participants were excluded from the study if they exhibited borderline or impaired general cognitive scores had a known history of severe perinatal events such as strokes or acquired brain injuries or psychiatric disorders associated with seizures Inclusion criteria required fluency in English and an age between 7 and 16 years The group of typically developing control participants consisted of volunteers recruited through advertisements and families expressing interest in participating in the study Typically developing control participants had no subjective concerns regarding academic achievement no prior diagnoses of neurodevelopmental disorders Most children in the clinical group (57 out of 75 76%) attended independent schools specifically tailored to children with learning differences allowing their teachers to provide detailed descriptions of their academic challenges The guardians of the participants provided informed written consent and the participants themselves provided assent The study was approved by the University of California San Francisco (UCSF) Institutional Review Board and complied with the Declaration of Helsinki the team of clinicians considered each child’s clinical history performed cognitive and academic evaluations and determined whether the child exhibited difficulties in mathematical cognition which aspect was most affected: number processing The assessment of these children’s mathematical abilities was not solely based on standardized assessments since their previous diagnoses primarily focused on cognitive and linguistic abilities mathematical abilities were also evaluated using the Woodcock–Johnson IV Test of Academic Achievement The clinical evaluation process began with a comprehensive assessment of the participant’s clinical history which carried significant weight in the overall evaluation If parents and teachers did not report any difficulties in math learning but the participant’s performance on a math subtest was below average the implications of the poor performance were carefully examined or subthreshold math deficits were considered Clinical impressions were formed based on a convergence of positive historical evidence of mathematical learning difficulties teacher-reported challenges in mathematics and either notably low performance on any math subtest (falling below the 5th percentile) or below-average scores across multiple math subtests 50 out of the 75 participants with a previous diagnosis of dyslexia were classified as having difficulties in some aspect of mathematics (66.6%) 10/50 (20%) were judged to have an overall impairment in mathematics experiencing difficulties in understanding basic concepts such as numbers and magnitudes These children were described as struggling to process numbers correctly teachers often reported that these children had trouble connecting numbers to their corresponding magnitudes while parents recalled instances during early learning when their child struggled with counting or understanding differences in quantities of objects The team classified these participants as having difficulties in number processing The majority of children who struggled in mathematics (32/50 64%) appeared to understand numbers but still faced challenges in calculation activities 16 children experienced difficulties primarily in mental or written calculations while the other 16 had impairments in memorizing multiplication tables and math facts The team classified these participants as having deficits in arithmetical procedures and arithmetic fact retrieval 8 out of the 50 children (16%) who struggled in mathematics were described as having difficulty with mathematical activities involving orientation and the processing of visuospatial information (such as reading graphs and comparing similarities and differences in figures) These children did not have trouble with calculations but struggled to understand mathematical concepts when presented visually The team classified these participants as having visuospatial difficulties which we identified as impairments in geometrical math abilities 25/75 children were classified as not having trouble in mathematics (33.3%) Among the 50 children with math difficulties 10/75 were classified as having impairments in number processing (13.3%) The UCSF Dyscalculia MCB was not used for the clinical impression evaluation The 75 dyslexic participants and the 18 typically developing children were tested with the UCSF MCB) to investigate whether new measures of mathematical cognition could be used to identify different mathematical deficits in this cohort of children each participant was tested for a total of 1 hour and fifteen minutes Performance and time were recorded for each subtest Each child was assessed with the battery tailored to the child’s grade level Children tested during the first three months of the scholastic year (until Christmas break) were evaluated with the battery tailored to their previous grade level to help alleviate didactical confounds 12 children were tested on the 2nd grade battery form Demographic, neuropsychological, and MCB measures were compared across groups (refer to Table 1) Group differences in MCB were evaluated to potentially classify mathematical cognitive deficits in children with dyslexia The data were analyzed using Stata 15 (StatCorp Parametric data were analyzed using ANOVA and independent sample t tests while non-parametric data were analyzed using chi-squared analyses Tests for unequal variances were employed as appropriate A Bonferroni correction was applied to account for multiple comparisons All statistical analyses were reviewed and The statistical analysis of group performance in the UCSF MCB is presented along with a general description of the performance in clinically defined groups The z scores were calculated based on the average of each group Further information on research design is available in the Nature Research Reporting Summary linked to this article The datasets generated and analyzed during the study are not publicly available because not all research on our project has been completed The data are available from the corresponding author upon completion of the study with protected health information excluded per HIPAA requirements and pending any other university obligations or requirements regarding data sharing No undisclosed code was used in this study Insider accounts of dyslexia from research mathematicians Prevalence of combined reading and arithmetic disabilities Dyscalculia and dyslexia in adults: cognitive bases of comorbidity Developmental dyscalculia: prevalence and demographic features The prevalence of specific arithmetic difficulties and specific reading difficulties in 9- to 10-year-old boys and girls The prevalence of specific learning disorder in mathematics and comorbidity with other developmental disorders in primary school-age children Mathematical skills in children with dyslexia Phonological processing and arithmetic fact retrieval: evidence from developmental dyslexia and executive functioning in preschoolers: longitudinal predictors of mathematical achievement at age 7 years Chapter 11 - Subtypes and comorbidity in mathematical learning disabilities: multidimensional study of verbal and visual memory processes is key to understanding Number sense and developmental dyscalculia and the developing brain: atypical development Digit dyslexia: a category-specific disorder in development dyscalculia Procedural dyscalculia and number fact dyscalculia: double dissociation in developmental dyscalculia Developmental cognitive neuropsychology of number processing and calculation: varieties of developmental dyscalculia Disabilities of arithmetic and mathematical reasoning: perspectives from neurology and neuropsychology The number sense: how the mind creates mathematics Numerical and arithmetical deficits in learning-disabled children: relation to dyscalculia and dyslexia Cognitive mechanisms in numerical processing: evidence from acquired dyscalculia Cognitive mechanisms in number processing and calculation: evidence from dyscalculia Developmental Dyscalculia: heterogeneity might not mean different mechanisms Number development and developmental dyscalculia Towards an anatomical and functional model of number processing Tuning curves for approximate numerosity in the human intraparietal sulcus Neurocognitive start-up tools for symbolic number representations Evidence for numerical abilities in young infants: a fatal flaw Two systems of non-symbolic numerical cognition Numerosity discrimination in infants: evidence for two systems of representations Brannon, E. M. & Merritt, D. J. Chapter 14 - evolutionary foundations of the approximate number system. In: Space, Time and Number in the Brain (eds. Dehaene, S. & Brannon, E. M.) 207–224 (Academic Press, 2011). https://doi.org/10.1016/B978-0-12-385948-8.00014-1 The effects of cross-sensory attentional demand on subitizing and on mapping number onto space Math difficulties in attention deficit hyperactivity disorder do not originate from the visual number sense Subitizing but not estimation of numerosity requires attentional resources Subitizing reflects visuo-spatial object individuation capacity Modulating attentional load affects numerosity estimation: evidence against a pre-attentive subitizing mechanism Relations of different types of numerical magnitude representations to each other and to mathematics achievement Associations of non-symbolic and symbolic numerical magnitude processing with mathematical competence: a meta-analysis Links between the intuitive sense of number and formal mathematics ability Impaired acuity of the approximate number system underlies mathematical learning disability (dyscalculia) From “Five” to 5 for 5 min: arabic number transcoding as a short and sensitive screening tool for mathematics learning difficulties Working memory deficits in developmental dyscalculia: the importance of serial order Symbolic and nonsymbolic number comparison in children with and without dyscalculia Developmental dyscalculia and basic numerical capacities: a study of 8–9-year-old students Ansari, D. The foundations of numerical and mathematical abilities: a literature review. https://openknowledge.worldbank.org/handle/10986/26821 (2012) Developmental trajectory of number acuity reveals a severe impairment in developmental dyscalculia Can Dyscalculics estimate the results of arithmetic problems Cognitive arithmetic and problem solving: a comparison of children with specific and general mathematics difficulties Cognitive analysis of children’s mathematics difficulties Selective impairment as evidence for mental organisation of arithmetical facts: BB How is phonological processing related to individual differences in children’s arithmetic skills Left angular gyrus mediates the retrieval of arithmetic facts during problem solving Arithmetic in the developing brain: a review of brain imaging studies Is finger-counting necessary for the development of arithmetic abilities The origin of mathematics and number sense in the cerebellum: with implications for finger counting and dyscalculia Stability and change in children’s division strategies An analysis of the counting-on solution procedure in addition Counting knowledge and skill in cognitive addition: a comparison of normal and mathematically disabled children The acquisition of addition and subtraction concepts in grades one through three A case study of arithmetic facts dyscalculia caused by a hypersensitivity-to-interference in memory Cerebral pathways for calculation: double dissociation between rote verbal and quantitative knowledge of arithmetic A deficit for arithmetical procedures: lack of knowledge or lack of monitoring Emerging neurodevelopmental perspectives on mathematical learning specific and otherwise: a neuropsychological perspective Spatial visualization and gender differences in high school geometry Importance of assessing spatial ability in intellectually talented young adolescents: a 20-year longitudinal study Development of sensitivity to geometry in visual forms A cortical representation of the local visual environment The fusiform face area: a module in human extrastriate cortex specialized for face perception A new neural framework for visuospatial processing Arm movement-related neurons in the visual area V6A of the macaque superior parietal lobule and visuoconstructive abilities in congenital hypothyroidism Massachusetts general hospital comprehensive clinical psychiatry (Elsevier The role of 2D and 3D mental rotation in mathematics for young children: what is it The effects of two-dimensional stimuli and three-dimensional stereoptic stimuli on spatial representation in drawings Effect of stimulus dimension on perception and cognition The representation of geometric cues in infancy The role of three-dimensional depth cues in infants’ perception of partly occluded objects The pupil responds spontaneously to perceived numerosity Reduced 2D form coherence and 3D structure from motion sensitivity in developmental dyscalculia Basic and advanced numerical performances relate to mathematical expertise but are fully mediated by visuospatial skills Developmental dyscalculia is related to visuo-spatial memory and inhibition impairment Working memory and arithmetic calculation in children: the contributory roles of processing speed The role of working memory in mental arithmetic Errors in multi-digit arithmetic and behavioral inattention in children with math difficulties Distinct representations of subtraction and multiplication in the neural systems for numerosity and language The relationship between reading fluency and arithmetic fact fluency and their shared cognitive skills: a developmental perspective The association between arithmetic and reading performance in school: a meta-analytic study Hippocampal-neocortical functional reorganization underlies children’s cognitive development Why do spatial abilities predict mathematical performance Effects of development and enculturation on number representation in the brain Calculation difficulties in children of very low birthweight: a neural correlate Brain hyper-connectivity and operation-specific deficits during arithmetic problem solving in children with developmental dyscalculia Hippocampal–prefrontal engagement and dynamic causal interactions in the maturation of children’s fact retrieval Effects of problem size and arithmetic operation on brain activation during calculation in children with varying levels of arithmetical fluency A distinct cortical network for mathematical knowledge in the human brain Contributions from specific and general factors to unique deficits: two cases of mathematics learning difficulties Are specific learning disorders truly specific In how many ways is the approximate number system associated with exact calculation Core knowledge of geometry in an amazonian indigene group Wechsler Intelligence Scale for Children | 5th Edition Nancy A, M. ATP: receptive one-word picture vocabulary test-4 (ROWPVT-4). https://www.academictherapy.com/detailATP.tpl?eqskudatarq=8547-8 Children’s color trails test 1 & 2: test–retest reliability and factorial validity California verbal learning test-second edition (CVLT-II) Rey complex figure test under four different administration procedures The Beery-Buktenica VMI: Developmental test of visual-motor integration with supplemental developmental tests of visual perception and motor coordination: administration Download references This work was made possible by the Charles and Helen Schwab Foundation and K24 DC015544 The authors thank the children who participated in this study and their families for the time and effort they dedicated to this research Faculty of Psychology and Educational Sciences Department of Epidemiology and Biostatistics and MG contributed to the conceptualization and design of the study BP and ME were involved in the implementation of the study and MG edited the first draft of the manuscript All authors contributed to the manuscript revision and read and approved the submitted version The authors declare no competing interests Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Reprints and permissions Download citation DOI: https://doi.org/10.1038/s41539-024-00217-x Anyone you share the following link with will be able to read this content: a shareable link is not currently available for this article Sign up for the Nature Briefing newsletter — what matters in science This website is using a security service to protect itself from online attacks The action you just performed triggered the security solution There are several actions that could trigger this block including submitting a certain word or phrase You can email the site owner to let them know you were blocked Please include what you were doing when this page came up and the Cloudflare Ray ID found at the bottom of this page By Rob Bates | November 28 a jewelry manufacturer with divisions in Italy and France Pedemonte Group was created in 2020 by the Equinox III SLP investment fund Villa Pedemonte Atelier and Vendorafa Lombardi The acquisition will allow LVMH to “significantly increase its production capacity,” a statement said adding that “existing workshops are mobilizing all their resources to support the strong growth of [LVMH’s jewelry and watch] division.” The company currently employs 350 artisans and employees said joining LVMH “will allow us to maintain our ambitions in terms of development training and strengthening of our human resources We will also pursue an ambitious investment policy to meet new challenges The acquisition will give LVMH “a partner recognized for its know-how to support their growth and maintain their leadership in jewelry,” said Antonio Belloni LVMH has made its jewelry and watch division a priority, particularly after it purchased Tiffany & Co. in 2021. Top: Worker at a Pedemonte factory (photo courtesy of LVMH) By Rob Bates May 05 By Annie Davidson Watson May 05 By Brittany Siminitz May 05 By Karen Dybis May 05 2025 © RX USA. Use of this website is subject to terms of use. Could you introduce your profession in a few words?  I am a Prevention Senior Manager, and I am part of the Safety and Risk Prevention department within the FOS (maintenance) division. I have four teams under my leadership, including the Safety Culture, Prevention and Operating Process, Quality Assurance and Quality Control teams, which bring together around forty Cast Members.   Since 2012, I have also been in charge of implementing the Disney “Wild About Safety” program in France and across Europe. This program – which represents one of the biggest projects of my career – aims at raising awareness about risk prevention among children.   Can you tell us about your professional journey within the company. Why did you apply for a position at Disneyland Paris?  Thereafter, I was compelled to leave Operations teams due to health issues. I continued my journey within the Human Resources division, where I took on various roles that notably focused on the development of training courses for new Cast Members and guest satisfaction analysis.    My career took a new turn when I joined the Safety division, and especially the “Safety Culture” team, whose mission consists of raising awareness and giving Cast Members the keys to adopt the right gestures for working in a safe environment every day. We also have implemented the “Wild About Safety” awareness-raising program and we were the first Disney Park in the world to promote it through the TV sets installed in our hotels.  My scope of responsibilities broadened over time, and I am now at the head of four teams:  I am assisted by fantastic teams, and I always tell people that “I don’t lead teams, but I am part of these teams,” because they help me grow as much as I strive to help them grow.  Our awareness-raising mission extends way beyond Disneyland Paris. Over the past two years, we have taken part in France’s biggest bicycle race event, and we even gave a presentation at the International Safety Education Summit to educate children on the safety issue. Wild About Safety is a program that is beloved by Cast Members because it makes it possible to teach safety rules to children in a caring and playful way.   Which teams do you collaborate with and how do you work together to ensure safety across the resort?   I collaborate with many teams, especially with the Maintenance department that conducts its operations both during the day and at night. I also work alongside Operations teams. Communications teams also help us bring numerous projects to life. All of the teams play a role in ensuring safety at Disneyland Paris.  Can you tell us about a project or a measure that contributed to strengthening safety across the resort, and of which you are particularly proud?  I am very proud of all of the projects we carry out in collaboration with passionate and engaged teams, but if I had to pick one, I would choose the safety culture project.  Our role is to make Cast Members realize that it is important to follow safety instructions to protect oneself and that their behaviors and choices may have a life-saving impact.  I am also particularly proud of the Disney Wild About Safety awareness-raising program, which is intended for children. Also, as part of the collaborative relationship we have had with the National Federation of Firefighters of France since 2016, we are going to raise awareness among children in schools. I think that if we manage to give children the keys to protect themselves in dangerous situations, our mission will be accomplished!   My many years of service have earned me many Disney Awards, but the reward that touched me the most was the Legacy Award. This reward is particularly important to me, and it shows that Disneyland Paris is truly appreciative of all our work. © Disney • Pixar © & TM Lucasfilm Ltd. © MARVEL. Tous droits réservés. We and our partners process information about you, your devices and your online behavior using technologies such as cookies for the purpose of providing, analyzing and improving our services, personalizing content or advertising displayed on this site and other sites, applications or platforms and to provide social networking functionality. More info in our Privacy Policy. Functional cookies are essential, allow basic functions and are necessary for the proper functioning of the website. Statistics cookies collect information anonymously. This information helps us understand how visitors use our website. Content from video platforms and social networks is blocked by default. If Advertising cookies are accepted, access to content from external media no longer requires manual consent. LVMH Group has announced the acquisition, from the Equinox III SLP SIF investment fund, of the Pedemonte Group, a jewelry producer present in Italy and France. This strategic operation for the Watches & Jewelry Division and its jewelry Maisons will allow the Group to significantly increase its production capacity, while the existing workshops are mobilizing all their resources to support the strong growth of the Division. The company currently employs 350 artisans and employees who will continue to provide, alongside the current management, their expertise, skills and know-how, often passed from one generation to the next, to support the production of jewelry pieces for all of its customers. “With this strategic acquisition for our Maisons, the LVMH Group further strengthens its presence in Italy while continuing to support the ecosystem of companies that contribute to the success of our Maisons. With Pedemonte, our Maisons will gain a partner recognized for its know-how to support their growth and maintain their leadership in jewelry,” says Toni Belloni, Deputy Managing Director at the LVMH Group. “We are very pleased to welcome the teams from the Pedemonte Group and its subsidiaries with whom we have been working for many years. Today our stories and our values come together around this spirit of excellence and enterprise, the perpetuation of craftsmanship and the development of creativity” adds Stéphane Bianchi, Chairman and CEO of the Watches & Jewelry Division. “We are extremely proud of the group’s history and growth. The deployment of a high-performance manufacturing platform has garnered the interest of an international player as relevant and important as LVMH,” comments Angelo Facchinetti, Partner at Equinox, a private equity firm. “Joining the LVMH Group is a source of pride and motivation for the entire management team and employees. This operation will allow us to maintain our ambitions in terms of development, training and strengthening of our human resources, the heart of our activities. We will also pursue an ambitious investment policy to meet new challenges, particularly in technology,” says Gian Andrea Garrone, Chairman and CEO of Pedemonte Group. Print Two Los Angeles police officers tried to intervene when a colleague intentionally struck a knife-wielding man with a department SUV last year in an attempt to disarm the man — a maneuver that the civilian Police Commission has now ruled was a clear violation of LAPD policy Commissioners agreed with Chief Michel Moore and an internal Los Angeles Police Department review board that found the officer, Oswaldo Pedemonte, had broken from policy when he drove into 31-year-old Jonathan Mitrani at a slow speed, knocking him to the ground during an encounter in North Hollywood last February. Mitrani had been walking toward the vehicle, knife in hand, after leading officers on a slow procession along Burbank Boulevard, during which police struck him several times with a stun gun and a projectile launcher. Moore concluded that Mitrani appeared intoxicated in police videos and did not pose an immediate threat to Pedemonte as the officer sat “in his police vehicle with the windows rolled up, protected by the ballistic panels,” the chief wrote in a report he presented to the commission. The review board had found that Pedemonte could have driven away if he felt he were in danger, and Moore agreed. “The Board noted that the Department does not train officers to use the police vehicle as an impact weapon and that there was no imminent threat to Officer Pedemonte or any other person to justify the use of the police vehicle in that manner,” Moore wrote. His report says that Pedemonte drove the SUV at 2 to 3 mph into Mitrani, who briefly grabbed the hood before being sent sprawling onto the pavement. California After picking an interim LAPD chief, L.A. Mayor Karen Bass told The Times she expects the nationwide search for a permanent replacement to take months. The incident, which drew significant news coverage at the time, began after a 911 call that reported Mitrani had shown up drunk and after curfew at a facility where he was living, in violation of the facility’s rules. A Los Angeles Fire Department dispatcher followed up with a request for police backup, saying Mitrani had a knife and appeared suicidal. Responding officers found Mitrani outside the facility and tried to get him to approach them, but he ignored their commands and instead began walking away. The review board unanimously condemned Pedemonte’s actions. Moore’s report also said that four officers involved in the encounter were late to activate their body cameras. Moore sided with the minority of board members who found that Pedemonte’s decision to get into his vehicle to follow Mitrani didn’t necessarily violate department rules. Pedemonte’s use of a Taser earlier in the encounter was found to be within policy. Other police actions during the incident were also found to be within LAPD policy or otherwise justified. The officers found to have violated policy could face discipline ranging from written reprimands to termination. Any proposed discipline is protected by privacy laws and can be appealed before the LAPD’s Board of Rights. Further appeals can be taken up in state court. Under department rules, an officer has a duty to intervene when they see another officer using unreasonable force. Upon seeing Pedemonte begin to drive toward Mitrani, Officer Geovanny Salazar and a supervisor, Sgt. Joseph Fleming, tried to intercede. Salazar yelled, “Wait, wait, wait, stop, stop, stop!” and Fleming repeatedly shouted, “No!” LAPD Chief Michel Moore told police commissioners that he had “concerns” after reviewing video of the fatal shooting of a man who charged at officers while holding a plastic fork Moore and the review board faulted Pedemonte for not alerting his fellow officers of his intentions when he got into the SUV and later drove into the suspect who is part of the LAPD unit that investigates serious uses of force Pedemonte said he feared being trapped inside the vehicle if Mitrani got any closer I’m gonna use the vehicle as an impact weapon,” Pedemonte said according to a transcript from the interview adding that he “did not want to run him over.” the civilian commission said that three Rampart Division officers were justified in fatally shooting a woman who had pointed what turned out to be a replica revolver in their direction While faulting one or more of the officers for not seeking cover at times and for using profanity officials said that their use of lethal force fell within policy because they opened fire only after the woman had pointed what appeared to be a real revolver at them The officers had no way of knowing in the moment that the gun was fake One of the involved officers was Jacqueline McBride, the daughter of a police union official. McBride, who also has a sister on the force, became the third member of her immediate family to shoot someone in the line of duty, according to previous reporting. Libor Jany covers the Los Angeles Police Department. Before joining the Los Angeles Times in 2022, he covered public safety for the Star Tribune in Minneapolis. A St. Paul, Minn., native, Jany studied communications at Mississippi State University. Politics Climate & Environment Subscribe for unlimited accessSite Map from the Equinox III SLP SIF investment fund a jewellery producer present in Italy and France The group said the strategic acquisition would significantly increase its jewellery production capacity Created in 2020 from the merger of several independent production workshops each with several decades of existence and experience the Pedemonte Group is today a recognised player in jewellery manufacturing With locations in the cities of Valenza and Valmadonna (Alessandria) in northern Italy the Pedemonte Group combines cutting-edge technology with artisanal craftsmanship It is involved in all the key stages of production and has demonstrated total excellence in execution in all its collaborations with LVMH Maisons The company currently employs 350 artisans and employees who will continue to provide sometimes passed from one generation to the next to support the production of jewellery pieces for all of its customers Deputy Managing Director of the LVMH Group “With this strategic acquisition for our Maisons the LVMH Group further strengthens its presence in Italy while continuing to support the ecosystem of companies that contribute to the success of our Maisons our Maisons will gain a partner recognised for its know-how to support their growth and maintain their leadership in jewellery.” “Joining the LVMH Group is a source of pride and motivation for the entire management team and employees This operation will allow us to maintain our ambitions in terms of development once a seemingly unstoppable force in the… In a landmark move for the jewellery sector A landmark auction at Sotheby’s Hong Kong on 7 May… Copyright © 2020 GJEPC | Kwebmaker The Pedemonte group was set up in 2020 following the merger of various independent jewellery production workshops, and is a mix of craftsmanship and advanced technology.The group’s VPA, Lombardi, Greco F.lli, Gieffedi and Thea workshops all produce jewellery for leading international brands. New Argentina coach Felipe Contepomi has named a much-changed squad for next month's tests with France and Uruguay, leaving out 15 members of the set-up at last year's Rugby World Cup. Among the big-name absentees from Contepomi's first full squad are ageing test centurion's hooker Agustin Creevy and fly-half Nicolas Sanchez as well as utility back Juan Cruz Mallia. Toulouse's Mallia, Bordeaux-Begles lock Guido Petti and La Rochelle prop Joel Sclavi are missing due to their end-of-season committment with their French clubs. Ex-Pumas playmaker Contepomi took over from Australian Michael Cheika after October's World Cup third-place play-off loss and assembled a training squad, without playing a game, in London earlier this year. Contepomi has selected four uncapped players. Brive prop Francisco Coria Marchetti, Vannes back-rower Bautista Pedemonte as well as lock Franco Molina and full-back Mateo Soler from the Dogos XV domestic side have yet to feature for the test side. Eleven members of the squad play their club rugby in France, including in-form Clermont winger Bautista Delguy. "This year is the starting point of a new World Cup cycle with the main objective of the Australia 2027 World Cup," Contepomi said in an Argentine Rugby Union statement on Wednesday. "We will put a lot of emphasis on the recovery of the players, and that is why several will have a rest and will be part of the squad rotation for other games in the year (the Rugby Championship and the November Window)," he added. Los Pumas play France on July 6 and 13 before a test against Uruguay a week later. They then play six games in The Rugby Championship before facing Italy, Ireland and Les Bleus again in November. FORWARDS: Matias Alemanno, Eduardo Bello, Bautista Bernasconi, Ignacio Calles, Santiago Coria Marchetti, Thomas Gallo, Santiago Grondona, Marcos Kremer, Pablo Matera, Franco Molina, Julian Montoya, Joaquin Moro, Joaquin Oviedo, Lucas Paulos, Bautista Pedemonte, Pedro Rubiolo, Ignacio Ruiz, Lucio Sordoni, Mayco Vivas BACKS: Tomas Albornoz, Lautaro Bazan Velez, Gonzalo Bertranou, Martin Bogado, Mateo Carreras, Santiago Carreras, Santiago Chocobares, Santiago Cordero, Jeronimo de la Fuente, Bautista Delguy, Gonzalo Garcia, Ignacio Mendy, Matias Moroni, Matias Orlando, Mateo Soler and where a recently opened boutique-restaurant–community hub offers a serenely chic place for them to shop It is called Etxe Nami which means “house” and “wave” in Basque and Japanese and is situated one quick TGV stop past Biarritz in the center of Saint-Jean-de-Luz (a quaint port town that hosted the moving final scene of Eric Rohmer’s 1986 summer-holiday classic Le Rayon Vert) The name and concept reflect the half-French half-Japanese heritage of founder Gloria Reiko Pedemonte a habitué of the Paris underground creative scene who decamped to the region two years ago after a decade-plus running the electronic music label Tsunami-Addiction Inspired by memories of the country home of her Japanese grandmother a storied early-aughts Paris canteen run by the influential magazine Pedemonte partnered with Paris-based chef Lena Balacco to create a multipurpose space she describes as “a spiritual initiatory journey that would dive me into my deep roots.” An adjacent garden offers ongoing workshops for the public It all makes for an experience far richer than retail—one that feels both radically new and completely natural in a region where time seems to stand still “The Basque country looks strangely like Japan and they have a lot in common: The ocean and mountain landscapes “We want to forge strong links between Japan and the Basque country by relying on crafts and tradition while combining them with modernity The space is an invitation to travel—to understand the cultures.” Etxe Nami, 11 Avenue Jaureguiberry, Saint-Jean-de-Luz, France; etxenami.com. Dear Reader,Unfortunately our comment platform isn\'t available at the moment due to issues with our paywall and authentication vendor Lisa Bencze was living for her wedding to the love of her life His beautiful and comical daughter’s wedding plans that’s what Mike Bencze would like to talk about But instead of a wedding there will be a memorial service Bencze (BEN-see) does his best to hold it together while speaking of his astonishment at the “most amazing” humanity revealed since everything abruptly changed for his Lisa who was born in Santa Rosa just 27 years ago 1 for Lisa and Matt Pedemonte was the marriage ceremony they’d set for this coming September at the lovely Sweet Lane Gardens then a massage therapist at Sonoma Mission Inn a surgical technologist at Sutter Santa Rosa Regional Hospital were friends well before they agreed it would be good to spend forever together had a blast starting to make wedding-day plans with the future bride - “just such a bubbly the discomfort she felt in her abdomen in November didn’t seem remarkable Then it became painful enough to warrant a trip to the doctor 13: She was suffering from an extremely rare and menacing cancer Her fiancé didn’t leave her side as she set off to consult with doctors as far away as San Diego and undertook aggressive therapies chemo treatments and a regimen of drugs that required a small travel case to tote the 30 bottles or more” of medications Lisa made a heartbreaking call to Sweet Lane Gardens She told Sweet of her illness and that she couldn’t be certain that she and Matt could marry on Sept ‘I don’t know if I’m going to be married on that date because I have to take care of this first.’” The owner of the wedding venue then declared to the ailing bride-to-be that once she beat the cancer she and Matt would come there to Petaluma Hill Road and have “the best goddamn wedding Lisa held tightly her resolve to marry Matt Given to me by the world’s most perfect guy,” she posted to Facebook on March 1 “And I don’t know exactly when it will happen anymore - but I can’t wait to become his wife “I can’t wait to stand on the beach on our honeymoon and feel the sand between my toes holding my husband’s hand knowing that we have already conquered our biggest battle I know that day will come and I can almost feel the sun on my face just thinking about it .. Lisa’s condition had worsened and her pain increased so much that she was admitted to Sutter’s Santa Rosa hospital She and Matt had to accept that there would be no wedding in the garden but they were determined to be married - right there in Room 2119 of the hospital’s Vineyard View wing It would be a far simpler wedding than originally planned a beauty made for her by Amparo Chavez of Santa Rosa’s Mariposa Seamstress shop But it no longer fit because of the weight she’d lost to her medical ordeal The seamstress was heartsick to hear of what Lisa That night she spent “four or five hours” making major alterations to the dress Chavez told them the gown was her gift to Lisa Family friend Ron Kamler reached out to the county clerk’s office the county’s new clerk-recorder-assessor-registrar of voters She offered to file the necessary marriage documents and to be at-ready around the clock to come to the hospital and conduct the ceremony all was ready for a wedding in Sutter Hospital Room 2119 But a mere two days after she’d been admitted The conclusion that an exchange of vows was not possible seemed as devastating to the nurses and other of the wing’s staffers as to Lisa’s sister and the dozen or so other family members and friends encamped there Lisa’s father stood in awe of the care and caring that his daughter and his entire family received from the staff “It was if they all looked at caring for Lisa as their mission in life and our family will be forever grateful,” he said He cheered to learn that in May the Sonoma County-based DAISY Foundation which acknowledges service beyond the call by nurses across the U.S honored Lisa’s nurses for all they did for his daughter and their family Time had to pass before her dad could talk about losing her and about the truly overwhelming kindness generosity and caring shown to her and all who loved her Though the planned September wedding won’t happen at Sweet Lane Gardens the proprietors are preparing to welcome in a few more days Lisa’s and Matt’s families and friends to a complimentary celebration of a life that was just splendid but far too short You can reach Chris Smith at 707-521-5211 or chris.smith@pressdemocrat.com The team from Brittany now joins the French elite This is historic as never before has Vannes played at the highest level in France It means that Vannes officially trade plays with the relegated Oyonnax for the 2024-2025 Top 14 season Getting there was far from easy but has come after investments in the roster and in transforming the club itself. Puma Francisco Gorrissen was part of the road to the Top 14. Gorrissen was signed from Super Rugby Americas to play for Vannes Gorrissen joined Vannes from Argentina in 2021. He captained the Pro D2 side to the play-off’s in 2023 and to the top spot of the Pro D2 during the 2024 season Gorrissen has made history by captaining Vannes to Pro D2 glory He did so while also having his contribution recognized as Gorrissen was named Man of the Match for Vannes in the Final The 29-year-old debuted for Argentina against Australia in the 2021 Rugby Championship. In 2024 he may add to his two test caps Felipe Contepomi will be rotating players in July ahead of the 2024 Rugby Championship The Pro D2 Final saw Gorrissen joined by Juan Bautista Pedemonte in the back-row. Pedemonte is also a former Super Rugby Americas player. He joined Vannes in 2005 Pedemonte will be a possibility for Contepomi’s roster in July The Brittany club is also adding a player from a third South American country. Iñaki Ayarza has been recruited from Charente Ayarza and Vilaseca offer the proposed of a Chilean-Uruguayan mid-field combination Both were starting players for their countries at Rugby World Cup 2023 Vannes will compete in the 2024-2025 Top 14 and the 2024-2025 Challenge Cup In recent seasons the gap between the Pro D2 and Top 14 has decreased This has been demonstrated by the ability of team to adapt and thus avoid relegation Vannes’ top priority will be to compete as such to remain in the competition and not be relegated straight back to the Pro D2 The club’s home venue is the Stade de la Rabine. The team has strong local support. It has a population of 55,000. The largest attendance was 11,865 for Vannes vs Dax in April Vannes recently announced a significant stadium upgrade The new modern facility will have a capacity of 10,000 This is the minimum requirement to compete in the Top 14 Argentine Marcos Moneta won the award for scoring the best Rugby SVNS try during the … Application Areas Coatings Technologies Legislation Markets & Companies People & Careers Production & Lab Raw materials Sponsored Content Home » News » Markets & Companies » DKSH distributes Kronos’ TiO₂ pigments for coatings in four countries sales and logistics for Kronos’ TiO2 pigments DKSH is a distributor of specialty chemicals and ingredients Kronos’ TiO2 is a white pigment that plays a key role in the production of paints and coatings It also plays a crucial role in specialties such as cosmetics Kronos has entrusted DKSH to grow its specialty chemicals business in Australia It follows their successful partnership in Portugal since 2017 and Spain since 2015 This is thanks to DKSH’s extensive distribution network strong capabilities in marketing and sales “We are very pleased to build on our established collaboration in Europe and expand into Asia Pacific where DKSH has been a leader in the distribution of industrial chemicals for a very long time We are confident that this extended partnership will deliver mutual and sustainable growth to both companies in all the four countries.” Atul Nagarkar “We are delighted to extend our partnership with Kronos to cover four new markets in Asia Pacific Kronos offers titanium dioxide products that are designed to provide excellent and long-lasting performance in a variety of applications With DKSH’s strong distribution network and value-added services we will be able to expand the growth and market share of their TiO2 pigments in the four main markets.” Demand for sustainable products continues to grow — but decorative coatings must also be durable Striking the right balance is one of the greatest challenges facing the.. has introduced three regional entities in Germany The aim is to decentralise the company’s structure have inaugurated a new laboratory in Shanghai The centre aims to strengthen innovation capabilities in the region US chemicals group Dow is considering the shutdown of two energy-intensive plants in Schkopau and Böhlen The decision follows market overcapacities rising costs and increasing regulatory pressures... Duncan Taylor will take over as interim CEO of Allnex on May 1 who will retire from the company on June 30 Taylor will continue to serve as Chief Financial Officer.. Marcus Jordan has assumed the role of Chief Executive Officer (CEO) of IMCD N.V Find the answers to the most frequently asked questions in our FAQ collection Equinox bought a 40% stake in Manifattura Valcismon produces cycling jerseys for the Castelli brand Preparations for the 2020 Super Rugby campaign continue Los Jaguares continues to make required alterations to the player roster due to the departure of players The latest newcomer is flanker Santiago Grondona who joins on a three-year deal Grondona has gone through the national system He played for Argentina in the U20 Championship from which he was called-up to Los Pumas by Mario Ledesma He would tour Europe in November 2018 but did so strictly as a tourist who remains uncapped In 2019 Grondona played for the Jaguares XV in the Currie Cup First Division and also received game time for the Argentina XV. He was in the team which defeated Uruguay in the RWC 2019 warm-up match in Montevideo last month For the match Grondona was joined by numerous Jaguares players. They were props Juan Pablo Zeiss and Lucio Sordoni; second-rower Lucas Paulos; fellow flanker and new Jaguares signing Bautista Pedemonte; scrum-half Gonzalo Bertranou; and winger Sebastián Cancelliere For Los Jaguares’ 2020 campaign Gonzalo Quesada will be without Santiago García Botta In addition Juan Manuel Leguizamón retired from Los Pumas last week meaning his retention as a Jaguar will not occur Grondona and Pedemonte are cover for Matera and Leguizamón There are likely to be others to join the remaining 2019 back-rowers  Rodrigo Bruni The 21-year-old Grondona has signed until the end of 2022 He is the third new signature following Pedemonte and winger Mateo Carreras Tags Rain showers this evening with overcast skies overnight Restaurateurs and brothers Peter and Lawrence Mammas Entertainment guru Andy Nulman and his old Just for Laughs partner Bruce Hills CJAD’s Dan Laxer and his new wife Yana Chirskaya PLAN B CASTING: CBC has announced the casting for a second season of the time-bending original drama series Plan B the main characters will be portrayed by Vinessa Antoine (Diggstown The Revenant) and Sarah Booth (Three Pines The new season follows Mia Coleman (Antoine) Via the mysterious Plan B agency she goes back in time to try and prevent a family tragedy from occurring Something to share? Email mcohen@thesuburban.com, follow me on Twitter @mikecohencsl and on our blog section at www.thesuburban.com Email notifications are only sent once a day Your browser is out of date and potentially vulnerable to security risks.We recommend switching to one of the following browsers: Join our newsletter for daily jewellery news Check if you already have access from your company or university South Pacific Cacao co-owner Jessica Pedemont South Pacific Cacao chocolate is unlike anything I’ve had in Australia One bar tastes like it’s been doused in honey Another smells like flowers and tastes like it’s been blended with toasted cereal grains Next season the same chocolate bars might taste like caramel or passionfruit Yet they contain nothing but roasted cacao beans and a bit of sugar This is how chocolate can be when it’s made bean-to-bar cacao beans can express an enormous variety of flavours and aromas particularly after they’re fermented (a key step in the production of all chocolate) Depending on the season and where the beans grown one crop can taste quite different to another are only apparent when the beans are carefully sourced from a single origin (one country or growing region) or single plantation (a single farm or small collective of cooperative farms) travel spots and more – curated by those who know That brings us to the other side of this story: South Pacific Cacao one of the few bean-to-bar chocolate shops in Sydney The Haberfield-based company is a joint venture between Jessica Pedemont and Brian Atkin She’s a former Rockpool chef with a flair for making chocolate He’s a Solomon Islander-Australian who runs Makira Gold a social enterprise that empowers Pacific Island farmers to ditch the low-quality low-margin farming geared for the commercial chocolate market All of South Pacific Cacao’s beans come from Makira Gold dried and packaged so it’s clear which beans are from which farmer Although the beans vary from season to season Pedemont knows roughly what flavour profiles are more pronounced in each farmer’s beans To produce the more distinct flavours – whether honeyed earthy or citric – and reduce the beans’ natural bitterness “Commercial bulk cocoa beans don’t have the fermentation needed for good quality chocolate We’ve done all kinds of work [and provided machinery] to help farmers improve their fermentation,” Atkin says Atkin and his team do a lot of work behind the scenes to make sure the Pacific Island beans are as high quality as possible Sometimes it’s as simple as providing a hermetically sealed bag for a long dinghy journey or maybe dealing with the complex problems related to the Solomon Islands’ huge rainfall and exorbitant electricity prices there will always be a few duds that need to be found and removed “The biggest component of flavour comes out of fermentation but roasting is one of the tools a chocolate maker can use to tweak the flavour,” Atkin says “A commercial roaster will roast the crap out of it,” Pedemont says organic beans that we don’t want to over roast.” Is it like coffee where a light roast brings out more of the bean’s inherent flavour and a dark roast results in a more generic flavour The process of separating the husk from the bean it’s incredibly finnicky and time consuming but Pedemont has invested in a custom-built machine just for this but she salvages hers and turns it into a tea (a tisane to be more precise) that smells and tastes like chocolate a viscous liquid before they can be shaped into bars How long and exactly how to conch is a big decision for a chocolate maker though it tends to be a two- or even three-day process Grind longer and you get a smoother texture but grind too long and the excess aeration will sap some of the flavour Some chocolate makers aerate on purpose by grinding with the lid off and the milk chocolate gets a bit of desiccated coconut (it’s ground down with the beans and used as a milk alternative) Usually cocoa butter would be added but the South Pacific beans are fatty enough The extras might include vanilla from the tiny island nation of Niue The process of turning liquid chocolate into a nice snap-able block It’s not as simple as just cooling it down and the final chocolate block will be crumbly and limp as a doona Tempering ensures the cocoa-butter crystals form in an ordered way The old school way is to pour the liquid chocolate onto a marble slab and slowly cool it getting those crystals to line up and create some structural integrity But Pedemont and most other modern makers use a machine Before the tempered chocolate completely cools and hardens South Pacific Cacao favours simple rectangles with prints on top The range usually stretches from a coconut-y melt-in-your-hand 50 per cent cacao product to a slightly bitter South Pacific Cacao’s stock-standard bar is the 70 to 75 per cent cacao a slightly granular and wildly flavoursome number that tastes like the best honey there is Pedemont’s second business at the same location Charcoal Chicken and Rosewater Desserts: A Local’s Guide to Merrylands Where Chefs Eat: Peter Gilmore Really Knows Crows Nest