Cloud is a compellingly tricky film to pin down, both stylistically and thematically. As Yoshii moves out of Tokyo into the countryside to focus on his shady business full-time, the film continues along this path, ramping up the isolation and paranoia along the way. Scenes are quiet until they’re suddenly not. The eerie soundtrack dips in and out. The acting is performed with an intentional lack of passion. Even the most extreme moments unfold with an increasingly unsettling reserve. Bauer Consumer Media Ltd, Company number 01176085; Bauer Radio Limited, Company number: 1394141; Registered office: Media House, Peterborough Business Park, Lynch Wood, Peterborough PE2 6EA and H Bauer Publishing, Company number: LP003328; Registered office: The Lantern, 75 Hampstead Road, London NW1 2PL All registered in England and Wales. VAT no 918 5617 01 H Bauer Publishing are authorised and regulated for credit broking by the FCA (Ref No: 845898) Yoshii (Masaki Suda) works in a factory, but he makes most of his money from online reselling. He buys goods – therapy devices, figurines, designer handbags – cheaply, and then sells them on again at an enormous markup. He’s so good at his side hustle, soon he’s able to chuck in his day job, and buy himself and his girlfriend Akiko (Kotone Furakawa) a picturesque house in the woods, with more than enough space for all his stock. But along the way to that success, Yoshii has made a lot of enemies, sellers and buyers alike, all of whom feel he has ripped them off. They are angry. They want revenge. Anyone who’s seen a film by Kiyoshi Kurosawa before knows that there are few directors better at instilling a seemingly innocuous scene with almost unbearable levels of dread. Whether he’s going full pelt or not – and Kurosawa at full pelt requires a mighty strong stomach! – he has an extraordinarily precise ability to control the tone of his movies from beat to beat; his plots often contain wild twists and turns, but you never feel like he has lost control. Cloud is split into two very distinct halves. In the first, we watch Yoshii as he goes about his days. Although he operates his business with an almost sociopathic single-mindedness, feeling no qualms about his dubious dealing, we see that he does at least have genuine feelings for Akiko – those feelings are the one thing that show he has a little bit of humanity. On a macro level, Cloud resounds with a general sense of dismay over the depersonalisation, the societal fracturing, of the gig economy. Alliances are drawn up over the course of the movie, but they are flimsy, self-serving ones, liable to be broken at a moment’s notice if those allied see a better offer on the table. It’s a vision of everyone as their own business, staring intently at their own computer screens, waiting to see if anyone is going to buy what they’re selling. Kurosawa has clear thoughts as to where it’s all leading, and that is nowhere good – but he sure does make the journey entertaining. Δdocument.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); BEIRUT (Lebanon) - As Akatsuki Japan continue to build the foundation of its national team program, you see many promising talents younger than 25 years old. You can see it in their list of players initially called up to the training camp in preparation for Window 6 of the FIBA Basketball World Cup 2023 Asian Qualifiers at the end of January the 24-year-old's journey is a bit different from his similar-aged peers The 1.96M (6'5") forward was not a featured star of youth national team programs like Yudai Nishida He hasn’t even played for a youth national team though he was a candidate to make the final roster for the U19 World Cup in 2017 who was not a part of the youth national team programs had made a name for himself as the NCAA Division I leader in assists back in 2018-19 Hirotaka Yoshii doesn’t have that kind of resume He’s played in Japan’s B.League ever since 2018 and has been a key piece of the mighty Alvark Tokyo for the past two years but it wasn’t as if he was lighting the league on fire I never thought about playing for the national team," Yoshii confessed suiting up as a starter for Akatsuki Japan as they tipped off against Australia in the third window of the FIBA Basketball World Cup 2023 Asian Qualifiers Not only was it his first time starting for the national team but it was also his first game with the national team ever I thought it was simply a great honor to play for the team." "Playing for Japan has been a valuable experience for me," He added "I don’t get many minutes in my club so I am thankful for being able to play in games with the national team I also think that it has been a good opportunity for myself and my name to be known to others." Yoshii was not just a one-time afterthought addition to coach Tom Hovasse’s roster either Yoshii also started three of five Asia Cup 2022 games and has been a part of the team in the Asian Qualifiers windows since Over the 11 games in 2022 that he played for the flag Among all of the players that have played for Japan this past year and Yudai Nishida have played more than Yoshii Not bad for someone who still has some doubt about his own level of play "There are times that I think I had a good play here and there," he admits "But I don’t think I am good at basketball yet." Coach Tom Hovasse might not entirely agree with his player on that While there’s still room for Yoshii to improve he’s certainly earned his part on the court for Akatsuki Japan His counting numbers (6.3 points and 3.5 rebounds per game in the Qualifiers) might not pop out This matches well with his choice of jersey number ("91") which is inspired by Dennis Rodman ("When I was in high school In his limited minutes playing for his professional club Yoshii specializes in playing defense against foreign players A large part of that is because of his height which allows him to better cover these "imports" who usually have that size advantage against the general local Japanese player His height was also a part of his basketball origin story ("I started playing basketball in third grade when the coach invited me to play because of how tall I was") and Yoshii has made good use of that ever since When Hovasse came on board as the head of the men’s national team Yoshii has been one of the staples of this program so far but considering the playing time that has been invested in developing Yoshii there seems to be a good chance that the young forward will be a part of the team that will play at the World Cup that will be co-hosted in Okinawa "There is only a small percentage of basketball players anywhere in the world who is able to play in the World Cup for their national team," he said "[To be a part of this program] is representing and playing with a lot of responsibilities." Yoshii considers himself as being lengths away from being a "good player" going up against physical teams like Australia and Iran and just learning from Yuta Watanabe at the Asia Cup he’s finding his role on the team and improving in that role with each passing game Even though he might not have an extensive resume as that of the majority of his teammates he built a strong one right now - one that could add FIBA Basketball World Cup 2023 experience real soon Please log in and check your service registration status.To cancel your subscription 1) === '|') document.write("&#"+unescape(l[i].substring(1))+";");else document.write(unescape(l[i]));} image: Mapping clock neuron connectivity enables the elucidation of mechanisms underlying circadian clock-related behaviors Drosophila is an ideal model for mapping this connectivity as they have a simple but conserved circadian clock neural network revealed the synaptic connectome of the circadian clock neurons in Drosophila Credit: Basisunus from Wikimedia Commons (https://openverse.org/image/61de2dee-fc34-4337-bf08-42b85d9538ff?q=drosophila+brain&p=14) enables organisms to respond to rhythmic environmental changes occurring over 24 hours The master circadian clock located in the brain regulates several peripheral clocks in different tissues through endocrine and systemic signaling The circadian clock neural network is highly conserved across species making the fruit fly Drosophila melanogaster an ideal model for circadian clock studies “The connectome developed in this study revealed the importance of clock neurons in regulating the feeding and mating behaviors of Drosophila.” Using the FlyWire connectome the researchers identified 242 clock neurons based on morphology “The number of clock neurons identified in this study is higher than the previously reported 150 neurons indicating the presence of novel neurons.” The study also identified new neuron subtypes and connections among different subgroups across both brain hemispheres DN1pA was identified as an important center linking the clock networks across the two brain hemispheres as it formed both ipsilateral and contralateral connections This extensive contralateral synaptic connectivity indicates that the neurons on the opposite sides of the brain are connected The study revealed that light input pathways influence clock neurons and ocelli provided indirect inputs to the clock neurons indicating a new layer of complexity in how light stimulus plays an important role in the functioning of the circadian neurons the study suggests that the output of the clock network neurons was directed toward the intrinsic brain neurons The clock network utilized descending neurons such as Allostatin-C and SIFamine (SIFa) peptidergic neurons Neurotransmitter analysis showed that most of the lateral clock neurons expressed the excitatory neurotransmitter acetylcholine whereas most of the dorsal clock neurons expressed glutamate “The inhibitory neurotransmitter GABA was absent in clock neurons Glutamatergic (small-central projecting DN3) and cholinergic clock neurons were involved in synaptic outputs to neurons that regulate hunger the study identified 12 neuropeptides that were upregulated in the clock network DH44 and Proctolin were the novel neuropeptides identified in this study This suggests that clock neurons communicate through peptidergic paracrine signaling These findings significantly improved our understanding of the connectivity and functioning of clock neurons and have potential implications for the development of therapeutic strategies for circadian disorders such as sleep and mood disorders in humans As one of the leading universities in Japan Okayama University aims to create and establish a new paradigm for the sustainable development of the world Okayama University offers a wide range of academic fields which become the basis of integrated graduate schools This not only allows us to conduct the most advanced and up-to-date research but also provides an enriching educational experience Website: https://www.okayama-u.ac.jp/index_e.html About Professor Taishi Yoshii from Okayama University Taishi Yoshii has been a Professor at the Graduate School of Environmental He completed his PhD from Okayama University in 2006 and his Master’s degree from Yamaguchi University He was awarded the Excellent Poster Award at the 19th Academic Conference of the Japanese Chronobiology Society He has published his research in various peer-reviewed journals and Biochemical and Biophysical Research Communications 10.1038/s41467-024-54694-0 Synaptic connectome of the Drosophila circadian clock The authors declare no competing interests are not responsible for the accuracy of news releases posted to EurekAlert by contributing institutions or for the use of any information through the EurekAlert system Copyright © 2025 by the American Association for the Advancement of Science (AAAS) Star pitcher Roki Sasaki thanked the Lotte Marines and their fans Sunday in his first public appearance since the club announced it will post him for a move to Major League Baseball this offseason Many MLB clubs are expected to woo the 23-year-old right-hander who was Lotte's first-round pick in the 2019 draft and has a 29-15 career record with a 2.10 ERA over four seasons with the Marines Speaking at a fan event at Lotte's home ground Sasaki vowed to "do my best in the United States." "All of the warm encouragement and tough love I've received will give me strength," he said introduced Sasaki at the event and urged Marines fans to continue supporting him "We have a player who will leave the Marines and challenge himself to reach new heights," Yoshii said "I would like to give him a warm send-off." Renowned as Japan's hardest-throwing pitcher the talented but injury-prone Sasaki threw a perfect game in April 2022 against the Orix Buffaloes Sasaki said there had been ups and downs but he was grateful for the support he received "There were times when things didn't go well because of injuries and other reasons but I was able to get through them thanks to the support of the manager Fans loudly applauded Sasaki and voiced their encouragement "Ganbare" meaning "do your best" in Japanese FOCUS: Baseball: Sasaki posting suggests flaws in Japan's system Baseball: Lotte to post flamethrower Roki Sasaki for MLB move To have the latest news and stories delivered to your inbox, subscribe here. Simply enter your email address below and an email will be sent through which to complete your subscription. Please check your inbox for a confirmation email. If you wish to change your message, press 'Cancel' to go back and edit. Thank you for reaching out to us.We will get back to you as soon as possible. "none"); */ } $("document").ready(function($) { let url = window.location.pathname; let nav_home = $('.only-home'); if (url != '/' && url != '/#') nav_home.removeClass("row"); }); $("document").ready(function($) { let url = window.location.pathname; let nav_home = $('.only-home'); let nav_home2 = $('.only-home2'); let nav = $('.without-home'); if (url != '') { $(window).bind('scroll load resize' "@id": "https://www.theworldfolio.com//interviews/Tsukaki-Shoji-Modernizing-Sampo-Yoshii/6487/" } "headline": "Tsukaki Shoji: Modernizing Sampo-Yoshii for the 21st Century" the Japanese textile manufacturer is striving to continue their sacred mission: to forever be good for the seller Please start the interview by giving us a quick introduction to your company I would like to begin by explaining the roots of our company There is a town under preservation in the Omi area of Shiga Prefecture Major Japanese companies such as Itochu and Marubeni started their business in the Omi area The first president of Toyota was also born in Omi Our company learned a lot from the philosophy of the Omi merchants we will have an event to spread the philosophy of the Omi merchants I am the sixth generation of Kizaemon Tsukamoto We have inherited the same name through the different generations It was the third generation of Kizaemon Tsukamoto who founded our current business My photo will be placed alongside the photos of my father and grandfather I will not put my photo next to the different generations We also have photos of the historic executive managers of the company dating back 150 years This was also a custom of the Omi merchants Itochu had similar customs a few years ago This painting is based on a painting by Korin Ogata Silk used to be one of the main import goods in Japan.  It was the top import for around 30 years The theme of this exhibition is Nishijin-ori and the Silk Road the Silk Road has been the main trade route in Asia The Silk Road extended from the west of the Eurasian continent all the way to Japan It created a large-scale economy throughout history and It was the way that technology for orimono passed from the West to the East Culture and designs were also spread through the Silk Road Chinese characters and Buddhism were spread this way The eastern end of the Silk Road was Nara in Japan Nara has the oldest tradition associated with the Silk Road As the theme of this exhibition is the Silk Road you can see the designs of each country here in our museum Some treasures are preserved in the Shoso-in Temple in Nara You can see the four different seasons here for example This is the design of the orimono for this particular area It was made using an 1800-hole jacquard weaving machine we opened our Tango Creative Center in Kyotango City Many of the craftsmen in the area were quite old The purpose of the center is to train the younger generations of craftsmen you can see a replica of the treasure in the Shoso-in Temple in Nara You can see products from both the East and the West here We also have Ancient Egyptian patterns on Nishijin textiles This exhibition shows the different cities and towns that the Silk Road passed through There are many designs from areas where Islam was the main religion we had a visitor from Thailand who needed to learn about the Silk Road they recognized the designs as you can find similar designs in Thailand You can see the details of the designs here There are a lot of different design types in China We have many different inspirations for designing kimonos here Our kimono designs incorporate many different aspects of the Silk Road Buddhism came from India to China through the Silk Road we have kanji characters and hiragana characters All of the writings related to Buddhism in India were translated into kanji in China The words of Buddhism inspired many of our designs We used the Nishijin-ori technique to make this item You can see Buddha being brought up to heaven The Buddha is wearing yellow clothes from India They are all made using orimono techniques Japanese Buddhism has many different rules from different religions Japanese people accepted all of these differences and backgrounds we reproduced a painting from 900 years ago with these new types of threads We weaved famous paintings such as Monet with the same threads We also weaved the Genji Monogatari which is an ancient Japanese story These were all done using the Nishijin-ori technique There is a weaving process and a dyeing process It takes around 10 months to design one of our kimonos you specialize in trading a wide range of fashion products with a particular focus on preserving traditional Japanese culture Among the products you offer is the kimono a garment that represents over 1,500 years of Japanese history you are also dedicated to creating original in-store products through collaboration with retailers Can you elaborate on your expertise in handling kimono products and explain how you strive to preserve tradition throughout the process we emphasized the opening of the Tango Creative Center on July 25th you can read the conversation that I had with the mayor of Tango We want to collaborate with the local government so that we can revitalize the local market The different weaving companies need to collaborate to make this happen you can see some photos from the Kaga Yuzen Women Artists Competition Kaga is another large area for the production of kimonos and is comparable to Kyoto Female designers have competed in this competition for the past 42 years We want to train young designers so that we can preserve and pass on our traditions We are also working together with the Outrigger Hotel in Waikiki Hawaii to build a chapel we collaborated with a coat retailer to host an event during the Gion Festival which is one of the biggest festivals in Japan We invited maikos (Japanese apprentice hosts one rank below geishas) and we were able to make many sales We do not only collaborate with retailers to develop original products We also have these kinds of events to sell our products and we have been able to diversify our businesses very well Your company focuses on seven different types of businesses which shows how you have managed to diversify your business throughout your many years of history Could you please give us an overview of your seven business divisions and the synergies that you can create among them which one do you believe has the most growth potential both for the domestic market and the overseas market as well The first is Tsukaki Shoji which is our original company It runs our museum and our Tango Creative Center The next company is Kyoto Wasou which specializes in Kaga Yuzen Both Tsukaki Shoji and Kyoto Wasou are wholesalers The third company is Kyoho which is a dye manufacturer for Kyoyuzen you can see photos of the weaving process for Nishijin-ori The next pages show the museum and the dyeing process You can also see photos of the Narutaki Creative Center and the technique that is called suminagashi or paper marbling It involves putting the dyeing material on the surface of the water and the craftsmen use various tools to create various designs you put the textile over the surface of the water Issey Miyake and Asics also used this technology This technology allows you to capture the moment of the design on the surface of the water These companies loved this concept and decided to use it we opened the Tokamachi Creative Center in Niigata Prefecture The supply chain in Kyoto is different from the supply chain in Tokamachi different steps are followed by different companies These different companies are connected like a chain There is also the issue of the aging craftsmen and we have opened the Tokamachi Creative Center in the area While Tsukaki Shoji was founded by the third generation He recently met with the Minister of the Mines there We conduct many different types of activities The fifth company in our group is Marie Classe They are located in Ginza and their business is wedding dress rental Our business in Hawaii will start in February of next year The final company is Tamura which is a foundation underwear business They have several patents to help women have better body shapes The first is real estate while the second is our financing business which one do you believe has the most growth potential for the domestic market and which one has the most growth potential for the overseas market We are still analyzing the potential for these businesses foundation underwear is limited to Southeast Asia due to the body sizes of the people there Japan has a historically deep clothing culture with its kimono and yukata characterized by timeless designs that have gone through improvement and modifications over the years Japan is famous for its cultural heritage and craftsmanship and innovative technologies integrated into the supply chain How would you define the uniqueness of the Japanese fashion and apparel industry It is a difficult question as we are engaged in the kimono business which is a little different from the apparel business The Japanese clothing business and clothing trends have been able to gain momentum in the global market A lot of this comes from the kimono-making process with the kimono being the traditional clothing of Japan To what extent do you believe the kimono has influenced the Japanese clothing industry we have an extensive network of department stores All these traditional department stores like Takashimaya and Mitsukoshi started their business as gofukuya when it comes to designers who have global activities they tend to incorporate the kimono traditions in their designs and oftentimes use the materials that are used for kimonos The kimono is still often used for important life events the kimono area is different from the typical apparel areas As for your second question regarding the strengths of the Japanese fashion industry it will be very difficult for it to continue to grow I believe that the strength of Japan lies in its weaving technology and its technology to produce original designs we have the tradition of incorporating international design elements.  These are Japan’s strengths in the global market.  You just mentioned that Japan’s strengths lie in its craftsmanship and its technology This is something that is under threat due to Japan’s aging population The first is a shrinking labor force which makes it difficult to pass on the accumulated know-how and manufacturing experience The second challenge is that the shrinking population will lead to a shrinking domestic market which is forcing Japanese companies to look abroad to find new opportunities How is your company navigating the challenges of a shrinking labor force and shrinking domestic market and to what extent are you looking overseas to continue the company’s corporate growth I think that those same trends can also be found in countries like Italy To overcome the challenge of the shrinking labor force we have been engaged in activities such as the opening of the Tango Creative Center which is focused on the training of the young generations We are collaborating with the local government and local associations of the industry it is very difficult to tackle the overall trend of the aging craftsmen The first involves training the young generation as soon as possible The other strategy is to ask the seasoned craftsmen to expedite the process of weaving so that we can stock the orimono There are some materials such as threads that will be difficult to produce in the future because the craftsmen who make those threads are also aging We are therefore asking these seasoned craftsmen to accelerate the production of these threads so that we can stock the important threads It is also important for us to look toward the overseas market We are now considering supplying the obi that we have weaved to overseas designers so we have not been good at collaborating with non-Japanese people That is what produced Japan’s closed society What types of artists are you looking to collaborate with Do you have any specific countries in mind that would be appealing to your obi business so we are trying to collaborate with the designers there to attract wealthy potential customers in the country we have a lot of similarities with Chinese dresses We are collaborating with a famous Chinese designer and are supplying the textiles for kimonos to them They carry out the dyeing process to make Chinese dresses that are sold at very high prices We have already spoken at length about your kimono business We are also very interested in understanding why your company decided to venture into the luxury jewelry business where you have been able to purchase demantoid garnet from Madagascar and bring it to Japan where you cut it to meet the needs of many customers not only in Japan but also around the globe What was the motivation behind expanding into the jewelry business could you please introduce the different brands that you have One of our motives was that we had the know-how needed for the jewelry business and the fur coat business as the know-how is very similar to the kimono business Some of the products that we make are worth JPY 1-2 million We also have channels for distribution in department stores and kimono retailers we were able to distribute our fur coats and jewelry Our diamonds are our best-selling products especially rare diamonds such as pink diamonds and red diamonds These diamonds are worth between JPY 10 million and JPY 100 million The other aspect of our jewelry business is to develop new color stones We have sold many different colored stones We noticed the need to find new colored stones That was why we decided to look into Madagascar Across the ocean from Madagascar lies Tanzania Madagascar is an isolated island with unique gemstones We dispatched our employees to the mines there and discovered different gemstones that we brought back to Japan it takes time for customers to learn about new color stones we were able to spread the information regarding these new stones and begin to distribute them what ambitions or goals would you like to achieve in the years to come and how would you like your company to be seen in the eyes of the global market We believe in the philosophy of the Omi merchants which is known as Sanpo-Yoshi or “three-way satisfaction.” This philosophy means being good for the buyers My dream is to spread this business philosophy to the world Kanji is one thing Japan has in common with those countries We also have similarities that derive from Confucianism and Buddhism That is why the philosophy of Sanpo-Yoshi has been widely accepted in East Asia It is a business style that teaches what society should be like I have made a lot of friends not only in Japan but also in China This company represents my business and my life I want to communicate Japanese traditions to the global market I would like to link these assets with the global market I will do my best for the company so that my sons and my employees can inherit these assets industrial and financial news about global economies with a focus on understanding them from within Japanese director Kiyoshi Kurosawa dives into the black market world of merchandising in his latest techno thriller There are very few directors that can build tension with just the scroll of a mouse or the click of a button From the Japanese director known best for techno-thriller Pulse and j-horror Cure Kurosawa's latest techno-thriller Cloud follows a young reseller in his descent into the black market world of merchandising The quality and authenticity of the products Yoshii resells are of little importance to him Kurosawa presents blackmarket dealing as a gambling addiction inviting audiences to watch Yoshii’s dead eyed glance as he watches the products on the screen When the anonymous item is desirable Yoshii’s screen quickly fills with red 'sold out' labels but his products don’t always sell and as his reputation as a dodgy dealer spreads online the obsessive reseller is left desperately chasing his purchasing high Cloud stands in bleak contrast with modern media's obsession with scammers Bling Ring) partly because despite exploring greed What makes Cloud different from these financially motivated thrillers is its lack of aspirational opulence Where Uncut Gems has gaudy diamond encrusted accessories and Spring Breakers has bags of cash Cloud only offers an unending number of boxes that are loaded onto Yoshii’s shelves unopened and return to his car and onto the courier in the same condition Their value is deemed by what the market for them is making them Schrodinger’s boxes an infinite number of unseen goods that matter only because of the demand of unseen buyers It is never entirely apparent whether Yoshii wishes for wealth in any extreme sense He clearly wishes for more than the exhaustion of the daily grind of the average worker with nothing to show for it Yoshii has some assemblage of aspirations beyond being a factory worker but he doesn’t yearn for material wealth His growing addiction to reselling goods seems instead to be his attempt at gaming life Yoshii’s downfall is not particularly unique or special Nor is there anything extraordinary about Yoshii’s desires or ambitions which is very much in keeping with Kurosawa’s characters Alongside an electronic hum that haunts much of his filmography even while descending into a protagonist's personal hell Kurossawa’s latest techno-thriller Cloud is arguably two movies in one The first act is a slow yet engaging crawl as Yoshii finds himself quickly entangled in the sticky matter of the dark web while the second is a brutal shootout sequence in which the people Yoshii has disregarded in his financial climb seek their revenge alludes to the vacuous desperation of our online worlds bringing strangers together in a chaotic bid for revenge Cloud is Kurosawa's latest film to critique digital society demonstrating how the internet casts a bleak shadow over our reality hollowing out its key players and leaving them stuck in a world where a win means more than life itself picturehouses.com escapism and design stories from around the world direct to your inbox Billie is a London based culture and lifestyle writer. Her work on film internet culture and sexuality can be found in Dazed This website is using a security service to protect itself from online attacks The action you just performed triggered the security solution There are several actions that could trigger this block including submitting a certain word or phrase You can email the site owner to let them know you were blocked Please include what you were doing when this page came up and the Cloudflare Ray ID found at the bottom of this page Feb 19, 2025 3:18 PM ESTFX’s Shogun series released in 2024 was a massive hit taking home a record-breaking 19 Primetime Emmys The critics and audiences were all in on the samurai drama set in 1600s Japan based on James Clavell’s novel but Jerry London was not feeling the most modern adaptation “Mine was based on the love story of Shogun between Blackthorne and Mariko and this new one is based on Japanese history who was the Shogun,” he told the outlet “It’s very technical and very difficult for an American audience to get their grips into it.” In the FX show, Blackthorne is played by Cosmo Jarvis, Mariko by Anna Sawai, and Toranaga by Hiroyuki Sanada According to London everyone he spoke to about the FX series couldn’t understand it and said the new filmmakers “didn’t care about the American audience.” What’s it all about?’ I watched the whole thing It’s very difficult to stick with,” he said London was happy the new series was not too similar to his because he “didn’t want my show to be copied.” which they didn’t do,” he said While London shares his gripes about the new series, FX has renewed it for two more seasons He has been a writer and editor at SPIN and Rolling Stone and has written for Vulture When he's not working he can likely be found attending a very cool concert or seeing one of his beloved local sports teams which will likely end up disappointing him He can be reached at luke.mccormick@mensjournal.com Sign up for our newsletter and be the first to hear about exclusive offers Confessions The modern master of Japanese horror discusses his latest a thrilling examination of the consequences of digital-age alienation Touted as the master of the Japanese thriller since the success of Cure in 1999 each release from Kiyoshi Kurosawa is anticipated as a promise of excellence The director presented his 27th feature film at the 81st Venice Film Festival this year and other biblical values with a Kurosawa-esque twist This is probably what seems strange with Cloud who found a way to make money by reselling online become the target of such deep resentment and violence “I originally wanted to make an action movie which is why you find violence in the film and no one seems shocked.” Kurosawa has a point as he touches on the human brain’s pliability – how we normalize something simply because we’re repeatedly exposed to it “But this violence also comes from the fact that these people meet online as if it was all a game!” Another point for the director normalizes the murderous impulses of humans exacerbated by our new means of communication which seemingly detach us from reality and critical thinking “I don’t know if it’s right or wrong but I didn’t intend to create a character that resembles me there’s probably a bit of me in all of my characters and now I’m very embarrassed because I feel like you’ve uncovered my secret!” the only female character and Yoshii’s fiancée is apparently the only one capable of eliciting emotions from him But while he will do everything to ensure they have a comfortable future and a proper marriage Akiko will begin to act increasingly strange as Yoshii’s troubles grow “I think Akiko is a symbol of hope for Yoshii even though she is an ambiguous character who cannot be labeled as good or bad as she doesn’t know what she thinks either It was at university that Kurosawa found refuge honing his craft before achieving his first major international success with Cure in 1997 Perhaps this is why the filmmaker seems attached to this institution From The Excitement of the Do-Re-Mi-Fa Girl to Cloud and Creepy Kurosawa’s plots often take place or refer to this learning space where friendships the relationships I have built during my college years have continued until this day it might have influenced my writing indeed But I wish to talk more about Tokyo and the people who live there when they come from rural areas leaving behind a crime scene worthy of CSI saved by his assistant with connections in high places you’ll be able to buy and sell as much as you want; we’ll be behind you to ensure everything goes smoothly.” The figure of the assistant hints at the rise of rampant capitalism and unbridled greed In the face of this assistant’s boundless loyalty Akiko’s betrayal seems all the greater: ‘When his only hope and only then can he finally realises what he has done and the kind of society he is in.'” set against a backdrop of a burning sky at sunset heading toward a fate where he can fully live his choices I think Yoshii realizes that hell is the world he was living in A world where most of the people who hate him have no hope And it’s only once he becomes aware of this that he can finally build another world you can interpret the ending however you like!” Despite its sometimes brutal and often absurd form as the characters’ reactions seem exaggerated Cloud encourages reflection on our world—a hell fueled by online networks that endlessly deepen the divide between humans lost in their own inability to connect with one another Jan 10, 2025 12:52 PM ESTBased on the 1975 novel by James Clavell, the epic historical series Shogun swept the 2025 Golden Globes although the 2024 drama was originally conceived as a limited series with just one season the popularity and acclaim for the series have made a second season more than just a wish there are several reasons to believe that Shogun Season 2 will actually happen sometime in the near future and Tadanobu Asano all taking home Golden Globes recently the details of Shogun Season 2 are still a bit murky Here's everything we know about the return of the samurai-heavy epic that is easily one of the best TV series in recent memory.  As of right now, there is no concrete release date for Shogun Season 2. The reason for this is because Shogun's new season has not started filming. After the 2025 Golden Globes, co-showrunner Rachel Kondo told Variety that the writing process is "ongoing," while her partner Justin Marks said the writers' room was about "six weeks" from mapping out Season 2 it's unlikely we'll know about the release date But work is happening on the show's story right now What Is Shogun's New Season About?The ambiguous ending of 'Shogun' Season 1 The final episode of Shogun Season 1 was Episode 10 "A Dream of a Dream," and it did not end on a cliffhanger one could argue that because the final episode showed Blackthorne (Cosmo Jarvis) rebuilding his ship it follows that Season 2 would have to let us know whether he was successful or not deal with the fallout of the deaths of Lady Mariko (Anna Sawai) and Kashigi Yabushige (Tadanobu Asano) There's also a scene of an elderly man on his deathbed who may or may not be Blackthorne at some point in the future.  Speaking to Slate in 2024 about the ending of Season 1 husband and wife co-showrunners Justin Marks and Rachel Kondo said: "There’s a little ambiguity that we’d like to stay there...we initially frame the story as if it were the recollection of an old man looking back on his life with regret in some way only to find that what we were really seeing was the dream of a young man looking forward with regret to the life that he could possibly have." Clearly, Season 2 would have to delve into these narrative complexities, and either make things more clear, or perhaps, even more layered. The show is now moving beyond the events of the original novel there will be even more creative narrative freedom than ever before Hiroyuki Sanada win Best Television Series - Drama for "Shogun" during the 82nd Annual Golden Globes held at The Beverly Hilton on January 05 (Photo by Rich Polk/GG2025/Penske Media via Getty Images) Assuming their characters didn't die in Season 1 most of the cast of Shogun could return for Season 2 With so many dreams within dreams, and memories of the past and possible futures haunting the characters of Shogun, it seems that in a sense, anything could happen, and the return of any character, is totally possible. Where to watch Shogun Season 1You can stream all 10 episodes of Shogun Season 1 on Hulu or Disney+. By Ryan Britt covers all things entertainment for Men's Journal He's written three critically acclaimed books on pop culture the making of Star Trek, and the history of Dune. He owns more James Bond novels and Sherlock Holmes books than is reasonable.  Volume 11 - 2018 | https://doi.org/10.3389/fnmol.2018.00409 Tuberous sclerosis complex (TSC) is an autosomal dominant neurogenetic disorder affecting the brain and other vital organs TSC is caused by a loss-of-function mutation in the TSC1 or TSC2 gene These gene products form a protein complex and normally suppress mammalian target of rapamycin (mTOR) activity mTOR inhibitors have been used to treat subependymal glioma (SEGA) that is a brain tumor characteristic of TSC neuropathology of TSC also involves dysregulated cortical circuit formation including neuronal migration It is currently unknown to what extent mTOR signaling inhibitors correct an alteration in neuronal morphology that have already formed prior to the treatment we address the efficacy of rapamycin treatment on neuronal migration and dendrite formation we suppressed Tsc1 expression in a fraction of neuronal progenitor cells during the fetal period we found that more Tsc1-suppressed cells remained within the periventricular zone and rapamycin treatment facilitated neuronal migration Tsc1-suppressed pyramidal neurons showed more complex branching of basal dendrites and a higher spine density at postnatal day (P) 28 Aberrant arborization was normalized by rapamycin administration every other day between P1 and P13 but not P15 and P27 abnormal spine maturation improved by rapamycin treatment between P15 and P27 but not P1 and P13 Our results indicate that there are multiple critical windows for correcting different aspects of structural abnormalities in TSC and the responses depend on the stage of neuronal circuit formation These data warrant a search for an additional therapeutic target to treat neurological symptoms of TSC These microscopic structural changes and functional alterations underlie neurological disabilities in TSC It is likely that the response to rapamycin is maximal while the abnormal morphology is formed it remains unclear whether each of these cellular processes has a sensitive period to respond to the mTOR inhibitor treatment we address the efficacy of rapamycin treatment on neuronal migration we transferred a DNA construct encoding Cre recombinase tagged with green fluorescent protein (Cre-GFP) into E 15.5 neuronal progenitor cells in a Tsc1fl/fl mouse fetal brain and suppressed the gene expression in a group of cells that are born around the same time we found that more Tsc1-suppressed cells remained within the periventricular zone and that rapamycin treatment facilitated neuronal migration the lamination pattern of Tsc1-suppressed neurons was widened and scattered more than WT cells Tsc1-suppressed pyramidal neurons showed more complex branching of basal dendrites which was normalized by rapamycin administrations between postnatal day (P) 1 and P13 but not between P15 and P27 abnormal spine maturation improved with rapamycin between P15 and P27 but not between P1 and P13 These results suggest that there is a critical time window during neuronal circuit formation to correct abnormal neuronal morphology in TSC Timed pregnant mothers were anesthetized with 2–3% isoflurane and oxygen the uterus was externalized and the lateral ventricle of E15.5 embryos was injected with 1–2 μg Cre-GFP alone or in combination with 0.1–0.2 μg DiO-YFP Using an ECM 830 apparatus (Harvard Apparatus Mouse embryos were electroporated at embryonic day 15 (E15) and acute coronal brain slices (240 μm) were prepared at E17 and E18 Occipital slices were transferred onto slice culture inserts (Millicell) in cell culture dishes (35 × 10 mm; Corning) with Neurobasal medium (Invitrogen) containing the following: B27 (1%) Slices were used for imaging (1–2 h after slicing) or for pharmacological treatments (incubated at 37°C in 5% CO2 A subset of slices was incubated with the medium containing rapamycin (100 μM) Cre-GFP- and mCherry-positive cells were imaged on an inverted Nikon microscope (TE 2000-S) with a 20 × objective lens [numerical aperture (NA) 0.45] mCherry was added to ensure fluorescent signal detection during serial imaging slices were kept in an acrylic chamber at 37°C in 5% CO2 We captured time-lapse images with a Cool SNAP EZ camera (Roper Scientific) using NIS-Elements software (Nikon) The neuronal migration velocity was measured using a plugin for ImageJ (Mouse Tracker, programmed by P. Malatesta, IST Genova) that allows tracking the cell position over time. Using the coordinates obtained with ImageJ, the velocity was calculated with Excel (Microsoft) (de Anda et al., 2010) Averaged pixel intensity was calculated by dividing total pixel intensities with the pixel area of cytosol averaged intensity of Cre-GFP signal was measured A cell was considered Cre-GFP positive when its averaged Cre-GFP intensity in the nucleus was above 100 Immunolabels of TSC1 and phosphorylated S6 were compared between neurons with and without Cre-GFP neurons expressing Cre-GFP (indicated with a dotted circle) shows suppression of Tsc1 protein as compared with neurons without Cre-GFP (C,D) Immunohistochemistry of p-S6 protein shows increases in neurons expressing Cre-GFP (labeled with a dotted circle) indicating overactivation of mTOR signaling A magnification of the neuron encircled by a white box is shown at the bottom and depicts the cytosol (a space between two yellow dashed lines) which is defined as ROI to measure immunolabels immunostaining was performed using an antibody to phosphorylated serine 240/244 of the S6 ribosomal pro- tein (pS6) Serial Z-stacks were acquired under the same settings for the ipsilateral and contralateral hemispheres of coronal sections Because layer 2/3 cortical neurons project to the contralateral hemisphere mRFP+ axons were followed to measure pS6 levels in cells of the non-electroporated region ROIs were generated using an elliptical selection tool and average intensi- ties for each ROI were determined The ROI did not include the nucleus that had low pS6 staining For both cell size and pS6 staining measurement 3 sections per mouse and 38–111 cells per section were analyzed Neurons were blindly traced and analyzed based on spherical shells concentric with the somal centroid and spaced at a 5μm interval The number of intersections and nodes were counted from the soma to the distal end of dendritic branches basal dendritic branches within the interval between 15–40 μm and number of spines were counted to calculate the spine density (number of spines per μm) To examine the migration of Tsc1-suppressed neuronal progenitor cells we combined a Cre-lox recombination system and in utero electroporation we used a Tsc1fl/fl mouse which has exon 17 and 18 flanked with Lox sequences and electroporated a DNA construct encoding Cre-GFP into wild-type (WT) or mutant fetuses at embryonic day 15.5 (E 15.5) We performed Immunohistochemistry in both WT and mutant brains at P28 and confirmed that Cre-GFP expressing neurons in the mutant showed suppression of the TSC1 protein (Figures 1A,B) and increased phosphorylation of ribosomal protein S6 (p-S6) (Figures 1C,D) indicating an enhanced mTOR signaling as a result of suppressed TSC1 function Tsc1-suppressed neurons show a scattered distribution and some cells are mislocalized outside of layer 2/3 the distribution of Cre-GFP (+) neurons is scattered Arrowheads indicate mislocalized cells and some of them are positive for the layer 2/3 marker Brn2 the distribution of neurons that were electroporated with Cre-GFP at E15.5 is consistent with layer 2/3 (C) The graph shows averaged percentage of Cre-GFP (+) cell in 10 segments as shown in (A) Cre-GFP (+) neurons in Tsc1fl/fl mouse brains is more widely distributed than those in WT *P < 0.05.**P < 0.01.***P < 0.001 dashed lines indicate the superficial and ventricular surface of the visual cortex These results indicate that Tsc1-suppressed post-mitotic neurons remain in the ventricular zone/intermediate zone longer than WT neurons and that rapamycin normalizes the departure timing once neurons leave the ventricular zone/intermediate zone Rapamycin treatment of the fetal brain slice corrected migration of Tsc1-suppressed neuronal progenitors (A) Fetal cortical slices that were prepared at E18.5 Cre-GFP (+) cells without rapamycin treatment appear to be balloon cells (arrowheads in the magnified image) and stay within the ventricular zone (C) In WT slice with or without rapamycin treatment rapamycin treatment resulted in subtle distribution changes In Tsc1fl/fl slice treated with rapamycin (100 μM) Cre-GFP (+) cells migrate to the cortical plate and are similar to progenitor cells in WT (except for Bin 1 and 3) Approximately 70% of Tsc1-suppressed cells without rapamycin treatment is localized in Bin 9 and 10 (D) The velocity of migrating cells is comparable between Tsc1fl/fl and WT brains these results suggest that the optimal timing to treat the dyslamination defect in the TSC1 cortex is prenatal when the majority of newborn neurons are migrating toward the cortical plate Postnatal administration of rapamycin does not correct the aberrant migration pattern of Tsc1-suppressed neurons (A) Representative images of the visual cortices collected from a Tsc1fl/fl mouse with postnatal rapamycin treatment and a WT animal (B) In Tsc1fl/fl animals that treated with rapamycin postnatally the distribution of neurons electroporated with Cre-GFP at 15.5 is wider than that in WT cortex Figure 5. Sholl analysis of electroporated pyramidal neurons. (A) There was no significant difference between Tsc1-suppressed and WT neurons in numbers of intersections throughout the apical dendrite. (B) WT and Tsc1-suppressed neurons with and without rapamycin treatment. Dashed boxes are magnified in Figure 6A (C) Basal dendrites of Tsc1-suppressed neuron had higher intersection numbers than WT cells between 15 and 40 μm from the soma rapamycin treatment between P1 and P13 but not between P 15 and 27 reduced the basal dendrite arborization ***P < 0.001 Error bars represent s.e.m Figure 6. Spine density of basal dendrites in electroporated pyramidal neurons. (A) Basal dendritic segments that are encircled with dashed boxes in Figure 5B The signal density of each image is inverted for an improved visualization (B) Tsc1-suppressed neurons have a higher spine density than WT cells at P28 Rapamycin treatment between P15 and P27 reduced spine density in Tsc1-suppressed neurons while neurons treated between P1 and P13 did not show a change in spine density cortical tubers alone may not be sufficient to explain neurological symptoms and microscopic abnormalities outside a tuber result in impaired circuit formation Using in utero electroporation and live cell imaging we find a scattered distribution of Tsc1-suppressed neurons Dyslamination results from the delayed departure of the mutant progenitors from the ventricular zone and is correctable with rapamycin treatment during neurogenesis postnatal administration of rapamycin did not correct malpositioning of Tsc1-suppressed neurons Our results indicate that mTOR inhibitor can correct the cortical lamination defect if it is given during corticogenesis While the result suggests cortical tubers and dyslamination are potentially treatable with a mTOR inhibitor the treatment is currently not feasible in a human embryo due to a concern for teratogenicity Neurons in different brain regions and ages have different local connectivity which is also likely to contribute to the interpretation abnormally elaborate dendritic arborization occur in response to up-regulation of mTOR signaling pathway Recent evidence suggests that each dendritic arbor process distinct information. For example, in a pyramidal neuron of the mouse visual cortex, each dendritic branch is tuned to a different orientation, and they are summated in the soma (Hausser, 2000; Jia et al., 2010; Grienberger et al., 2015) Further study is needed to address whether dendritic integration and sensory processing are dysregulated in Tsc1-suppressed neurons Our results indicate that there is a critical period for rapamycin response to normalize exuberant dendritic branching of Tsc-1-suppressed neurons that correspond to the first 2 weeks of postnatal life mTOR pathway is responsible for dendritic arborization in an early postnatal period before spine maturation occurs We also find that the rapamycin effect on aberrant spine formation is optimal between P15 and P27 when activity-dependent synapse formation is at its peak While rapamycin treatment is effective in correcting dendritic spine formation our results suggest that there may be a limit in compensating for the structural changes preceding mTOR inhibition further studies are needed to understand whether there is an additional therapeutic target to further improve neuronal connectivity RC and FCdA performed experiments on migration and contributed to writing the manuscript The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest AY is supported by DoD TSCRP Career Transition Award (W81XWH-09-1-0088) NARSAD Young Investigator Award and University of Illinois at Chicago start-up funds FCdA is supported by Deutsche Forschungsgemeinschaft (DFG) Grant (FOR 2419; CA1495/1-1; and CA 1495/4-1) ERA-NET Neuron Grant (Bundesministerium für Bildung und Forschung Landesforschungsförderung Hamburg (Z-AN LF) and University Medical Center Hamburg-Eppendorf (UKE) The Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fnmol.2018.00409/full#supplementary-material A neural circuit for spatial summation in visual cortex Lateral competition for cortical space by layer-specific horizontal circuits Therapeutic value of prenatal rapamycin treatment in a mouse brain model of tuberous sclerosis complex Multimodality imaging for improved detection of epileptogenic foci in tuberous sclerosis complex Quantitative visualization of ictal subdural EEG changes in children with neocortical focal seizures Loss of Tsc1 in vivo impairs hippocampal mGluR-LTD and increases excitatory synaptic function Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations Neuronal and glia abnormalities in Tsc1-deficient forebrain and partial rescue by rapamycin Neocortical neurogenesis: morphogenetic gradients and beyond Tuberous sclerosis complex proteins control axon formation Laminar and compartmental regulation of dendritic growth in mature cortex Dendritic arbor development and synaptogenesis Molecular pathogenesis of tuber formation in tuberous sclerosis complex Centrosome motility is essential for initial axon formation in the neocortex Prognostic significance of tuber count and location in tuberous sclerosis complex Reversal of learning deficits in a Tsc2+/– mouse model of tuberous sclerosis European Chromosome 16 Tuberous Sclerosis Consortium (1993) Identification and characterization of the tuberous sclerosis gene on chromosome 16 Single-cell Tsc1 knockout during corticogenesis generates tuber-like lesions and reduces seizure threshold in mice Adjunctive everolimus therapy for treatment-resistant focal-onset seizures associated with tuberous sclerosis (EXIST-3): a phase 3 Regulable neural progenitor-specific Tsc1 loss yields giant cells with organellar dysfunction in a model of tuberous sclerosis complex Molecular logic of neocortical projection neuron specification Diversity and dynamics of dendritic signaling Critical period plasticity in local cortical circuits Increasing knowledge of PTEN germline mutations: two additional patients with autism and macrocephaly mTOR signaling: at the crossroads of plasticity Experience-dependent and cell-type-specific spine growth in the neocortex Control of dendritic arborization by the Phosphoinositide-3'-Kinase-Akt-mammalian target of rapamycin pathway Dendritic organization of sensory input to cortical neurons in vivo Linkage of an important gene locus for tuberous sclerosis to a chromosome 16 marker for polycystic kidney disease Epilepsy surgery in children with tuberous sclerosis complex: presurgical evaluation and outcome Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis Pten regulates neuronal arborization and social interaction in mice Dynamic remodeling of dendritic arbors in GABAergic interneurons of adult visual cortex Sustained activation of mTOR pathway in embryonic neural stem cells leads to development of tuberous sclerosis complex-associated lesions Cytoarchitectural alterations are widespread in cerebral cortex in tuberous sclerosis complex The neurobiology of the tuberous sclerosis complex Response of a neuronal model of tuberous sclerosis to mammalian target of Rapamycin (mTOR) inhibitors: effects on mTORC1 and Akt signaling lead to improved survival and function A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons Tsc2-Rheb signaling regulates EphA-mediated axon guidance Subcellular patterning: axonal domains with specialized structure and function the product of the tuberous sclerosis 1 (TSC1) gene interacts with tuberin and appears to be localized to cytoplasmic vesicles Development and plasticity of the primary visual cortex The leaving or Q fraction of the murine cerebral proliferative epithelium: a general model of neocortical neuronogenesis Cell-specific alterations of glutamate receptor expression in tuberous sclerosis complex cortical tubers Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2 Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex van Slegtenhorst Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34 van Slegtenhorst The differential effects of prenatal and/or postnatal rapamycin on neurodevelopmental defects and cognition in a neuroglial mouse model of tuberous sclerosis complex Activity-dependent regulation of dendritic growth and patterning Tuberous sclerosis complex: correlation of magnetic resonance imaging (MRI) findings with comorbidities BDNF induces transport of PSD-95 to dendrites through PI3K-AKT signaling after NMDA receptor activation Postsynaptic BDNF-TrkB signaling in synapse maturation TrkB and protein kinase Mζ regulate synaptic localization of PSD-95 in developing cortex Eye opening induces a rapid dendritic localization of PSD-95 in central visual neurons Tsc1 mutant neural stem/progenitor cells exhibit migration deficits and give rise to subependymal lesions in the lateral ventricle Mangoubi T and Yoshii A (2018) Multiple Critical Periods for Rapamycin Treatment to Correct Structural Defects in Tsc-1-Suppressed Brain Received: 30 June 2018; Accepted: 18 October 2018; Published: 08 November 2018 Copyright © 2018 Cox, Calderon de Anda, Mangoubi and Yoshii. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) distribution or reproduction in other forums is permitted provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited in accordance with accepted academic practice distribution or reproduction is permitted which does not comply with these terms *Correspondence: Akira Yoshii, YXlvc2hpaUB1aWMuZWR1 Department of Anatomy & Cell Biology Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher 94% of researchers rate our articles as excellent or goodLearn more about the work of our research integrity team to safeguard the quality of each article we publish Today's print edition Home Delivery A district court on Thursday referred to the family court a case involving a 16-year-old boy charged with murdering his parents in the city of Sagamihara Yokohama District Court Judge Takahira Yoshii said that educative and protective measures are appropriate for the boy.googletag.cmd.push(function() { googletag.display('div-gpt-ad-1499653692894-0'); }); "The incident wouldn't have happened if he had not been placed in an inappropriate environment by his parents," the presiding judge said Yoshii said that the boy "regrets" what he did and that he needs to receive special education Public prosecutors had sought a prison sentence of 10 to 15 years for the boy The judge found the boy guilty of killing his 52-year-old father and 50-year-old mother at their home near Tokyo on Feb by stabbing them multiple times in their necks with a knife He was in his first year of high school at the time The boy had admitted to murdering his father while claiming that he killed his mother because she had asked him to The defense argued that this amounted to a case of assisted suicide Yoshii noted that the mother had gone out to the balcony to seek help which contradicted the defense's claim The defense pointed out that the boy was a victim of severe maltreatment and had become desperate after enduring many years of physical and mental abuse by his parents waited for his mother to return home to kill her due to his strong homicidal intention In a time of both misinformation and too much information quality journalism is more crucial than ever.By subscribing Your subscription plan doesn't allow commenting. To learn more see our FAQ Sponsored contents planned and edited by JT Media Enterprise Division serves as a memoir for Paul Gonzenbach (lead singer/songwriter) and his summer 2003 bout with severe mental illness disturbing lyrics painted beautifully on the canvas of intelligent pop music The messages of grief and despair are unpretentiously laid out before you as if you were watching your best friend contemplate jumping from the top of a building on a beautiful afternoon Picks Us Apart is not all doom and gloom: There is a lot of hope in the unspoken lines The music of JYPU is at times mellow and lush but can also be fuzzy and angry similar to the lyrics of the Red House Painters; they also have the disposition of Joy Division I talked to the lead singer/songwriter Paul Gonzenbach about touring songwriting and the homoerotica of Elvis Presley: The Jim Yoshii Pile-Up has recorded with Christopher Walla (of Death Cab for Cutie) They are about to embark on the most extensive tour they have ever done to support an album Donate $10 OR MORE to get a SLUG sticker pack SLUG Mag is one of Utah’s longest-running and most experienced independent magazines SLUG has given a voice to Utah’s community and continues to expand its coverage in both print and digital media Kumiko Kakehashi's So Sad To Fall In Battle: An Account of War Based on General Tadamichi Kuribayashi's Letters from Iwo Jima is a masterpiece. I find this book challenging as it reveals the depth of my own ignorance This is the story of Lieutenant General Tadamichi Kuribayashi. Five months before Japan's surrender on August 15, Kuribayashi led a fierce battle against overwhelming American forces on the isolated island of Iwo Jima Kakehashi's book reveals that Japan's Imperial General Headquarters (IGHQ) altered his famed death poem "Unable to complete this heavy task for our country so sad we fall" was the original first line in the poem the IGHQ changed "so sad we fall" to "so bitterly we fall." Kakehashi presents 41 letters that Lieutenant General Kuribayashi sent to his family from Iwo Jima I also read Kuribayashi's letters and telegrams from Iwo Jima in 1995 This was a decade before the publication of Kakehashi's book I was then conducting interviews for the series "Voices Without a Voice: The 50 Years of War Dead's Families." Despite the chaos during and after the war the family managed to preserve the letters from Iwo Jima carefully I focused not on their content but on how the family read them "Have you ever seriously considered developing your willpower establishing a family as a man will be challenging Lieutenant General Kuribayashi had addressed this letter to Taro He drew red lines next to "developing willpower" and "challenging future," hoping Taro would remember his father's teachings There was also a letter addressed to Yoshii Yoshii had personally obscured these sections which included lines such as "My remains will likely never return..." The post-war life of the Kuribayashi family once venerated as the "House of the War God," underwent a dramatic change Both Yoshii and Taro spoke little about their post-war hardships during the interviews the silent voices of Kuribayashi's wife and children can be heard clearly through his letters CAPTION: A letter from Lieutenant General Kuribayashi to his wife I also had the honor of interviewing Takako decades ago. Back then, she was the head of a kindergarten in Kawaguchi City, Saitama Prefecture "Relatives of the soldiers who died on Iwo Jima came to our house on several occasions asking for money," she revealed Takako related this story in an interview at the kindergarten I remember seeing posters of her eldest son In July, I met with politician Yoshitaka Shindo (66) in his ministerial office, which overlooks the National Diet Building Shindo is Takako's son and Lieutenant General Kuribayashi's grandson.  Some 30 years after my interview with his mother he has become a member of the National Diet Yoshitaka Shindo is shouldering a significant responsibility always telling me to reflect on how I should conduct myself," he said "Our relatives often say that she's the one who most inherited Tadamichi Kuribayashi's personality." Shindo remembers her as "elegant and never angry I can't recall ever seeing her laugh genuinely "We can never truly heal the sorrow of war," Shindo opined "It is our responsibility to ensure that our country never experiences such devastation again." I recently visited the Kuribayashi family for the first time in about 30 years Yoshii passed away at the age of 99 in 2003 Kuribayashi's eldest son Taro passed away the year after that to review the letters from Iwo Jima once more She kept them in a plastic file along with paraffin paper to protect against moisture also a granddaughter of Lieutenant General Kuribayashi faces the challenge of preserving these historically valuable documents who published her new book War Museum: Connecting the Circuits of Memory "As long as the family wishes to keep the letters there comes a point when these personal items become 'historical testimony.'" She worries where the family should entrust the Iwo Jima letters at that juncture "There is no museum in Japan that provides a complete overview of the war," she explained We are approaching the 80th anniversary of the end of the war next year I could hear the "silent voices" from Iwo Jima.  Read the article in Japanese Author: Kinya Fujimoto You must be logged in to post a comment ' + scriptOptions._localizedStrings.webview_notification_text + ' " + scriptOptions._localizedStrings.redirect_overlay_title + " " + scriptOptions._localizedStrings.redirect_overlay_text + " Please view the main text area of the page by skipping the main menu. The page may not be displayed properly if the JavaScript is deactivated on your browser Japanese version Your request appears similar to malicious requests sent by robots Please make sure JavaScript is enabled and then try loading this page again. If you continue to be blocked, please send an email to secruxurity@sizetedistrict.cVmwom with: going back to school provided the insight and perspective he felt he needed for the latest chapter of his long and varied baseball career The 58-year-old Yoshii called an end to a 24-year pro career after the 2007 season having pitched for four teams in Japan's majors as well as Major League Baseball's New York Mets did not arm him with the knowledge he felt was required to be the coach he wanted to become a lot of things about coaching were difficult," Yoshii told Kyodo News on Wednesday at Yokohama Stadium "I lacked confidence that the things I told players to do were right Because what a coach says can impact a player's career I asked myself if it was OK to be so careless Yoshii coached for Nippon Ham Fighters manager Hideki Kuriyama but quit in 2012 It was the first of two times Yoshii would leave after the two had a falling out but it did not prevent Kuriyama from wanting the coach on his Japan World Baseball Classic staff in 2023 Yoshii undertook a master's course in physical education at Tsukuba University to dive deep into answers that would improve his coaching "I've become able to enter into a kind of scientific objective mode as a result of the coursework I was required to do," Yoshii said After a coaching stint with the SoftBank Hawks and a second with the Fighters he oversaw fire-balling young right-hander Roki Sasaki's careful initiation into pro baseball and helped guide him on the path to becoming Japan's youngest perfect-game pitcher in 2022 Yoshii said the Marines did not let Sasaki pitch in any games in 2020 because of how slowly he recovered from the arm inflammation that comes with pitching Sasaki's bone density was widely reported to be low a sign that his bones had not fully developed something Yoshii had learned was relatively common "Baseball needs to be very careful with players turning pro out of high school because adding too much muscle on those with immature bones can lead to injuries." without depending solely on practical experience Through talking about different things with different players the scope of my understanding grew broader still." His experience and education made Yoshii an attractive candidate for a managing job he didn't particularly want suddenly quit the Marines after the 2022 season "It (managing) is a lot of trouble," Yoshii said But as to whether he has learned anything from sitting in the big chair since last season "I'll let you know after we win a championship." FEATURE: Trailblazing female baseball coach aims for Japan pro ranks To have the latest news and stories delivered to your inbox Simply enter your email address below and an email will be sent through which to complete your subscription Please check your inbox for a confirmation email Thank you for reaching out to us.We will get back to you as soon as possible Japanese version Yoshii Toranaga is a powerful bushō from a feared lineage and lord of the expansive Kanto Region He is isolated and outnumbered by his enemies in Osaka Castle when the story begins But little does anyone realize that Toranaga is a brilliant strategist and a master of the long game Blackthorne finds more than he bargained for when his ship washes ashore in Japan Mariko is deeply faithful and darkly determined Yabushige is Lord of Izu within the Kanto Region SaveLog in, register or subscribe to save recipes for later.You have reached your maximum number of saved items Remove items from your saved list to add more Add articles to your saved list and come back to them anytime You’re going to need black belt-level online booking skills to secure a reservation at this handsome omakase counter set inside Nobu at Crown. New seats are released at noon on the first day of each month, and with space for only 10 diners at a time, demand is much greater than supply. Nimble fingers are rewarded with a first-class experience courtesy of Ryuichi Yoshii and Hyota Sugihara who share jokes with guests and prepare Sydney’s best sushi. Nigiri is the main event, including imperador, blue mackerel, chu-toro and ume-licked bonito among the highlights, plus leatherjacket and the defined flavours of its kombu-marinated liver, and squid scored and scalded to bloom like a flower. Composed courses are in their own league too, from the jewel box of beautifully sculpted sashimi treasures to start, to a wagyu kushiyaki skewer tiled with truffle, foie gras, Tasmanian sea urchin and caviar. Exclusive stuff, indeed. Good Food hatGood Food hat17/20Review17 courses, 10 guests, more than two years to book: Is Yoshii’s Omakase worth the $350 price tag?Continue this series XOPPBig-ticket energy fuels Golden Century’s spin-off. SaveLog in, register or subscribe to save recipes for later.You have reached your maximum number of saved items Rika Yoshii grew up in Point Loma wanting to become a rock star she found her passion at Cal State San Marcos where she has served as the chair of the Computer Science and Information Systems Department and is now the interim faculty director of the new Master of Science in cybersecurity program “San Diego is a cybersecurity hub,” said Yoshii “We have many military installations and we have many defense industry partners all in the area So it is really important to have a good cybersecurity program.” But this isn’t just any cybersecurity program It is the only professional science master’s program in cybersecurity in the state and one of just a handful in the nation “We are creating the future leaders who can be chief information security officers in computer science from UC Irvine and worked as a project leader at Rockwell and a researcher for the Northrop Research and Technology Center before joining the computer science department at CSUSM in 1993 to pursue her love of teaching Her areas of expertise include developing adaptive intelligent tutoring software “I love teaching more than anything else,” Yoshii said “Even my research is related to learning CSUSM is where I can help a diverse population of students reach their full potential Without them I would not be where I am today I want to encourage and help all students to become whatever they want to become.” Graduate School of Economics of Kobe University he serves as vice editor of Russian and East European Studies (the Japanese Association for Russian and East European Studies) and is a managing member of the Japan Economic Policy Association Sign up to receive the Gourmet Traveller newsletter and offers we choose to share with you straight to your inbox  By joining, you agree to our Privacy Policy & Terms of Use “Wow,” whispers a fellow diner after downing a meltingly plush bonito nigiri dabbed with umeboshi paste “This is insane,” her partner cries out later on between spoonfuls of meringue-soft Hokkaido sea urchin and Kaluga caviar draped over impeccably cooked and vinegared rice Visceral reactions like these aren’t uncommon at the 10 chairs along chef Ryuichi Yoshii’s opulent counter set-up His rarefied sourcing powers and knife skills are obvious in a quick-fire succession of sushi that dazzles in every small bite but the in-between moments are just as commanding Whistle-clean strands of snow crab and ocean trout roe in a hollowed-out yuzu lull you into submission early and if the soufflé-textured tamago doesn’t elicit your complete surrender it’ll be the concluding chestnut Mont Blanc with sake-lees mousse Gourmet Traveller is Australia’s trusted authority on food bringing the latest news and trends to life through quality journalism enticing recipes and evocative photography it has been inspiring and informing Australians with the best in cooking Our critics bring the expertise of years of critical eating as the country’s leading title in the luxury sector Gourmet Traveller works closely with Australia’s leaders in the travel and hospitality industries to give our readers exclusive access The Gourmet Traveller legacy is one of trust While Shōgun may tell the story of the fictional warlord Yoshii Toronaga his exploits are based on the life of a real historical figure who ruled Japan – the revered Tokugawa Ieyasu Bringing to life the world of feudal Japan, Shōgun is the story of a nation on the edge of a samurai civil war where honour is everything and life is fast and fleeting The series, streaming on Hulu in the US and Disney+ in the UK, is a lavish adaptation of James Clavell’s 1975 historical fiction novel of the same name Much of the plot revolves around Yoshii Toranaga a fabled warrior and one of five regents ruling the country following the death of its supreme leader Already there are plots in the dark about who should step into the void left by the taiko’s death but nonetheless Shōgun is based on real history a thinly veiled analogue of a real warlord and shōgun – Tokugawa Ieyasu The character of Yoshii Toranaga in Shōgun is inspired by the life of warlord and later shōgun From more than a century of near-constant civil war laid the foundations in the late-16th century who fought alongside both Nobunaga and Hideyoshi He went from child hostage to feared warlord to military dictator, and in the process established a shōgunate that lasted 265 years Born with the name Matsudaira Takechiyo in 1543 the future Tokugawa Ieyasu was the son of a daimyo (large landowner) Although the Matsudaira family claimed ancestry to the prodigious Minamoto clan which ruled Japan from the 12th to 14th centuries and counted the first shōgun among its number they were a minor power based in Mikawa province The Sengoku (‘warring states’) period had been raging for decades by now It was a time of relentless fighting and civil strife between the daimyos that kept Japan divided The ever-shifting loyalties of Ieyasu's father meant that the boy was just four or five when he was offered as a hostage to secure an alliance with a strong neighbouring clan While being transported from his home at Okazaki Castle to the Imagawa base at Sunpu who threatened to kill him if the Matsudaira did not abandon the proposed alliance The boy was spared and lived with the Oda for several years Takechiyo received military training and education in matters of governance He also became clan leader after his father’s death in 1549 and father 11 sons and five daughters – and personally led forces on campaign against the Oda circumstances had changed: the Imagawa clan was in disarray while an impressive warrior named Oda Nobunaga had taken over the Oda and launched a mission to unify the country by force.Ieyasu saw an opportunity to return to his family’s domain and assert his own control Emerging as a new daimyo to be reckoned with Takechiyo would take a new name too: Tokugawa Ieyasu Ieyasu rose in prominence and expanded his territory thanks to the alliance with Oda Nobunaga who had become the most powerful man in Japan Nobunaga died after being betrayed by one of his vassals Into this vacuum stepped Nobunaga’s brilliant general Toyotomi Hideyoshi As part of the ongoing attempt to unify the country the two joined forces to defeat the dangerous Hojo clan Ieyasu was offered Hojo provinces to the east as long as he gave up his existing territory Despite the risks of starting anew in unknown lands Ieyasu moved his administration to a small fishing village called Edo where he immediately embarked on a massive construction project to transform the area into a political centre to rival Kyoto and a cultural hub for artisans and businessmen became the foundations of the modern-day Imperial Palace Tucked away in his eastern corner of Japan he avoided getting caught up in Hideyoshi’s ill-fated military invasions of Korea Tokugawa was among the most powerful daimyo and appointed one of the ‘council of five elders’ tasked with ruling on behalf Japan of Hideyoshi’s young son he would seize the chance to take power for himself Those loyal to Hideyoshi’s wishes for his son Hideyori to rule formed a faction against Ieyasu but his so-called Eastern Army defeated the Western Army of Ishida Mitsunari at the decisive battle of Sekigahara in 1600 Ieyasu shook up the political landscape by moving them to different parts of the country confiscating land from enemies and giving it to allies he split the daimyos into three classes – shinpan (those related to the Tokugawa clan) fudai (his loyalists) and tozama (those who swore fealty after Sekigahara) – which each had varying degrees of restrictions within his new system He was awarded the title of shōgun by the emperor of Japan in 1603 marking him as the pre-eminent warlord in the land this meant little as he continued to rule anyway yet the move established his shōgunate as a hereditary title in the hopes of preventing future claims from other daimyos Having let Hideyori remain at Osaka Castle for years Tokugawa ultimately defeated this last rival in 1615 Tokugawa initially welcomed trade with European merchants and allowed missionaries to operate he came to see foreigners as a threat to his dictatorial order so he forbade Christianity and curtailed traders This laid the groundwork for Japan’s isolationist policy William Adams began working in a shipyard at the age of 12 and was involved in the defeat of the Spanish Armada in 1588 before joining a fleet of Dutch merchant ships bound for the East Indies his ship anchored off Japan and he was brought before Ieyasu in the months before his victory at the battle of Sekigahara The Englishman impressed Ieyasu so much that he became a trusted advisor and the shogun lavished him with land and a title where he helped build ships and set up a factory for the East India Company Just as Ieyasu was the inspiration for Toronaga in Shōgun, John Blackthorne is loosely based on William Adams Tokugawa died of an illness at the age of 73 A magnificent mausoleum and shrine would be erected in Nikko the Tokugawa Shōgunate ruled Japan: a time of peace but achieved through rigid and often ruthless control It ended only with the Meiji Restoration in 1868 which re-established direct imperial rule once again The series, streaming on Hulu in the US and Disney+ in the UK, is a lavish adaptation of James Clavell’s 1975 historical fiction novel of the same name Hiroyuki Sanada as Yoshii Toranaga in Shōgun (Photo courtesy of Kurt Iswarienko/FX)The character of Yoshii Toranaga in Shōgun is inspired by the life of warlord and later shōgun Enter your email address now to receive the real history behind the latest releases By entering your details you are agreeing to our terms and conditions and privacy policy This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply He went from child hostage to feared warlord to military dictator, and in the process established a shōgunate that lasted 265 years The ever-shifting loyalties of Ieyasu's father meant that the boy was just four or five when he was offered as a hostage to secure an alliance with a strong neighbouring clan Just as Ieyasu was the inspiration for Toronaga in Shōgun, John Blackthorne is loosely based on William Adams Jonny WilkesFreelance writerJonny Wilkes is a former staff writer for BBC History Revealed and he continues to write for both the magazine and HistoryExtra He has BA in History from the University of York you are agreeing to site title terms and conditions and privacy policy New Product Development for Smith Travel Research (STR)She is responsible for developing new products to supplement STR’s current offerings Her current projects include a customer satisfaction platform and a forward booking product Yoshii has 21 years of global lodging industry experience She has a broad background which includes internal audit Yoshii was Senior Director of (Worldwide) Research for Hilton Hotels Corporation She received a Bachelor of Science degree in Accounting from Christian Brothers University I became project leader for the SENDAI UMINO-MORI AQUARIUM in July 2014 My job was to manage the schedule and make sure we hit all our milestones There were seven companies involved in the project some from Sendai and some from the Tokyo region they all had their own views on what sort of aquarium we should make My role—in conjunction with Yokohama Hakkeijima the firm responsible for the marine exhibits—was to interpret and realize all the different parties’ aspirations but one thing was never in doubt: we all wanted to create something very special there was a lot of discussion about whether to include an exhibit of the local marine life of northeast Japan people there felt understandably ambivalent toward the sea we were keen to create an aquarium that had a distinct and we wanted to make people aware of that We ended up installing a giant aquarium with a northeast Japan theme It accounts for about one third of the total exhibition space and has proven very popular I spent several years working on the Hiroshima Carp baseball team which is based in the Hiroshima Zoom-Zoom Stadium I brought that skill set up to the aquarium in Sendai No one had sold such a large sponsorship program for an aquarium before but I devised a variety of packages to pitch to potential sponsors visitor numbers fluctuate according to the team’s performance whereas the flow of people to aquariums is pretty constant we managed to raise in sponsorship for the first year The most important thing is to make sure that’s sustainable and to get our partners to renew next year necessarily has an impact on the local community One aspect of my job was to get up on stage at town hall meetings explain our plans and reassure residents that we would do our best effort to prevent traffic jams There was a lot of anticipation locally before the opening I used to spend about half the week up in Sendai and when I was on the train or in restaurants I’d often hear people talking about it It attracted 500,000 visitors in its first two months of operation We are now expecting to exceed our original target for the first year I was lucky to be put in charge of this project and given so much latitude I’m relatively young—in my mid-thirties—so it was a precious opportunity I took my own kids to the aquarium in August 2015 and they had a great time I think it was one of their best memories of the summer holidays Now that SENDAI UMINO-MORI AQUARIUM is up and running in the sense that we both own and operate the facility so before we embark on another similar project we need to verify that it works as a business and is delivering all-important value for our shareholders we may explore working on another facility somewhere else COPYRIGHT © 1996-2025 MITSUI & CO. Metrics details The Original Article was published on 21 July 2017 The effects of NGM on the proteome of S a–c Two-dimensional (2-D) electrophoresis in the presence or absence of NGM or 17DN (a DMSO control; b NGM; c 17DN) whose expressions were decreased in the presence of NGM on 2-D gel Yutaka Yoshii and Ken-ichi Okuda contributed equally to this work Jikei Center for Biofilm Science and Technology Core Research Facilities for Basic Science The original article can be found online at https://doi.org/10.1038/s41522-017-0026-1 Download citation DOI: https://doi.org/10.1038/s41522-017-0038-x Anyone you share the following link with will be able to read this content: a shareable link is not currently available for this article Sign up for the Nature Briefing newsletter — what matters in science She issued a notice on September 13 to Galaxy Play asking it to publicly express regret for divulging her private life to the public without her consent "Em Va Trinh," a biopic on Trinh Cong Son (1939-2001) has a character playing Yoshii and reveals a lot of details about her relationship with Son Yoshii wanted an apology through a press release within seven days She also wants the apology included in the film every time it is screened and the producer to make a pledge not to do something similar again The production company merely said it has received the notice from Yoshii and made no further comment claimed her client remained silent when the film was released for fear of affecting its revenue who is involved in many charity initiatives in Vietnam saw the film and was reportedly taken aback to see a lot of inaccuracies and her character (played by Japanese actress Nakatani Akari) canceling her wedding with Son (played by Tran Luc) and returning to Japan One of the primary plot developments of the film is the love story between Son and Yoshii in the late 1980s when she falls in love with Vietnamese culture Despite having a master's degree in Japanese culture she is pursuing a master's degree in Trinh Cong Son's anti-war music She travels to Vietnam to meet a writer she admires and Son's music and master thesis bridge their relationship her brother and Michiko once intended to marry but it failed to go ahead for unknown reasons Yoshii successfully defended her thesis on the influence of Trinh Cong Son's anti-war music in wartime Vietnamese society in Paris in 1991 and examiners at the University of Paris VII graded it as excellent Now Yoshii frequently visits Vietnam and burns incense at Son’s grave She is currently a professor at Mie University's Center for International Education and Research in Japan "Em Va Trinh" has been biggest Vietnamese hit this year with box office collections of more than VND100 billion (US$4.2 million) But it has sparked a lot of debate and received mixed reviews Some viewers have said the portrayal of the musician in the film is different from what they understood from reading about him Others said Son's connection with Yoshii was wrongly depicted changing him into a shallow person while in love According to the production company, it had attempted to "relive the legend" of Trinh Cong Son and therefore mistakes were unavoidable The work is a biopic and not a documentary and this was made explicit at the start of the film by the disclaimer "inspired by real characters," it pointed out Email: evne@vnexpress.netTel: 028 7300 9999 - Ext 8556 Hiroyuki Sanada has closed a deal to return as Lord Yoshii Toranaga Hiroyuki Sanada has closed a deal to return as Lord Yoshii Toranaga – which means a season 2 is likely on the horizon and the Latin American streamer Star Plus in just the first six days of its release Shogun follows "the collision of two ambitious men from different worlds, John Blackthorne a risk-taking English sailor who ends up shipwrecked in Japan a land whose unfamiliar culture will ultimately redefine him; Lord Toranaga a woman with invaluable skills but dishonorable family ties who must prove her value and allegiance." It's based on the 1975 Jams Clavell novel of the same name which is considered to be a work of historical fiction Created by Rachel Kondo and Top Gun: Maverick writer Justin Marks So far Sanada is the only cast member who has signed on to reprise their role Shogun season 1 is streaming now on Hulu. For more, check out our list of the best new TV shows coming your way in 2024 and beyond Tv & FilmLauren Milici is a Senior Entertainment Writer for GamesRadar+ currently based in the Midwest She previously reported on breaking news for The Independent's Indy100 and created TV and film listicles for Ranker A 23-year-old man was found guilty Wednesday of killing a protected deer in a popular park in the western Japan prefecture of Nara earlier this year The Nara District Court sentenced Hayato Yoshii to 10 months in prison for attacking the deer with an ax around 2 a.m are protected under Japan's cultural properties protection law "The defendant did not value the animal's life His act was brutal and malicious," Judge Risa Ishikawa said in handing down the ruling to Yoshii noting his motive for the attack was that he became furious after one of the deer suddenly rammed his car but that cannot justify his action He was accused of violating the law that protects cultural properties after killing the female deer Police were notified by a passerby about the attack and identified the suspect using surveillance camera footage of the area the court also found Yoshii guilty of drunken driving in Matsusaka and possessing a Japanese sword without authorization The sword was found when his home in the city was searched by investigators on March 2 Year's 1st deer fawn born in Nara Park in western Japan Man arrested for killing protected wild deer in Nara, western Japan Deer-friendly digestible paper bags developed in Japan