Jason Lemon is a Senior Politics Editor at Newsweek based in Brooklyn, New York politics and international affairs. He joined Newsweek in 2018 and had previously worked as an editor at a Middle Eastern media startup called StepFeed He also worked a year as a contributor to The Atlanta Journal-Constitution and has bylines in The Christian Science Monitor Al Fanar Media and A Magazine. He is a graduate of the American University of Beirut in Lebanon and Andrews University in Michigan You can get in touch with Jason by emailing j.lemon@newsweek.com either observed and verified firsthand by the reporter or reported and verified from knowledgeable sources Translations may contain inaccuracies—please refer to the original content President Donald Trump dismissed price increases on common items purchased by consumers in a Sunday interview with NBC News' Meet the Press saying "that's peanuts compared to energy." The Trump administration has had to defend its decision to apply a 145 percent tariff on Chinese products raising concerns about the severe impact on pricing that the tariffs will cause Chinese online marketplace Temu has halted shipments directly from China to the United States as the U.S government eliminated the "de minimis" exception for Chinese goods which would have exempted shipments under $800 from the tariffs Trump underscored his defense of the tariffs saying: "Maybe the children will have two dolls instead of 30 dolls and maybe the two dolls will cost a couple of bucks more than they would normally." Trump made the comment after Meet the Press host Kristen Welker pressed him about how the cost of specific items—including tires strollers and clothing—have increased "in the wake of your tariffs." "That's peanuts compared to energy," the president responded Gasoline is thousands of times more important than a stroller some place," Trump continued adding that mortgage rates are going down "despite the fact we have a stubborn Fed." Welker continued to ask the president on the potential impact of tariffs referring to his quote about dolls and asking if it was an acknowledgement of the potential cost of tariffs on everyday goods "I don't think a beautiful baby girl that's 11 years old needs to have 30 dolls," Trump said "I think they can have three dolls or four dolls because what we were doing with China was unbelievable We had a trade deficit of hundreds of billions of dollars with China." Trump added that he's not saying Americans will see "empty store shelves," but rather that "they don't need to have 250 pencils They can have five," later saying that "we don't need to feed the beast." The tariff concerns remain even as the Trump administration received great news from the jobs market, with April's jobs report show that the U.S. added 177,000 jobs which has fueled fears of an oncoming recession Speaking on the matter of such contrasting elements within the same economy I think the good parts are the Trump economy and the bad parts are the Biden economy He did a terrible job on everything from his auto pen some of the things he was supposedly signing..." but I've only just been here for a little more than three months look at what's happened in the last short period of time." "Didn't it have nine or 10 days in a row or 11 days where it's gone up and the tariffs have just started kicking in and we're doing really well," Trump continued the fake news was giving me such press on the tariffs Welker: When does it become the trump economy? Trump: It partially is right now, and I really mean this. I think the good parts are the Trump economy and the bad parts are the Biden economy pic.twitter.com/mjmnTWlPDh Welker took the opportunity to also address the case of Kilmar Abrego Garcia was arrested in 2019 and accused of being a member of the MS-13 gang which the Trump administration has designated a foreign terrorist organization Abrego Garcia and his legal team have denied he is a member of the gang based on confidential information provided to the court He was shielded from deportation to El Salvador because he said he would be targeted by MS-13's gangland rivals who lived in Maryland with his wife and children was deported to El Salvador in March after being arrested in what the Trump administration lawyers said was an "administrative error." His family denies any ties to gangs and Abrego Garcia has no criminal record in the U.S. although his wife accused him of domestic violence and obtained a restraining order against him He has been ordered to return to the U.S. by U.S. District Judge Paula Xinis and a recent decision by the U.S. Supreme Court instructed the Trump administration to "facilitate" Garcia's release and return, but the White House has resisted efforts Trump recently said he could bring Abrego Garcia back but would not do so. He also said it "wouldn't bother" him to bring Abrego Garcia back stateside but said he ultimately is letting the Department of Justice (DOJ) determine the next steps When Welker pressed him on his comments about the situation and the limits of his power to affect the situation he reiterated his view that ultimately the DOJ will determine what happens And they're not viewing the decision the way you said it They think it's a totally different decision." Trump added: "I have the power to ask for him to come back if I'm instructed by the attorney general that it's legal to do so but the decision as to whether or not he should come back will be the head of El Salvador is a very capable man." Ahmed Baba, co-founder and president of Rantt Media, wrote on X, formerly Twitter on Sunday: "While Trump proudly raises prices on Americans and preaches scarcity he is grifting hundreds of millions of dollars in his crypto ventures as he directly profits off the presidency Just an unprecedented level of corruption while he economically harms everyday Americans." Labor Secretary Lori Chavez-DeRemer told Fox Business on Friday that Trump "mentioned to the American people over and over again that the Golden Age was coming I will tell you the Golden Age is here...This is another great jobs' report...Better than expected." asked whether he was concerned about empty shelves recently told Fox & Friends: "Not at present .. and then we will see how quickly the Chinese want to de-escalate." The impact of the U.S. tariffs on Chinese products are expected to start taking effect in around five to seven weeks after ports work through already stockpiled goods, with Port of Los Angeles Director Gene Seroka saying he expects to see "less choice and higher prices" once the tariff effects kick in ET: This article has been updated with additional information Newsweek is committed to challenging conventional wisdom and finding connections in the search for common ground Newsweek is committed to journalism that is factual and fair We value your input and encourage you to rate this article Newsletters in your inbox See all First clinical trial of its kind could be ‘life changing’ for those living in fear of severe peanut reaction Adults with severe peanut allergies can be desensitised by daily exposure according to the first clinical trial of its kind After being given steadily increasing doses of peanut flour over a period of months two-thirds of the trial participants were able to eat the equivalent of five peanuts without reacting The findings suggest that the window of opportunity for treating allergies could extend into adulthood raising the prospect of new treatments for those severely affected “Constant fear of life-threatening reactions place a huge burden on people with peanut allergy,” said Stephen Till the professor who led the research at King’s College London “The only way to manage a peanut allergy is strict avoidance and treatment of allergic reactions “Although peanut immunotherapy is known to be effective in children this trial provides preliminary evidence that adults can also be desensitised and that this improves quality of life.” The Grown Up Peanut Immunotherapy (GUPI) trial recruited 21 adults aged between 18 and 40 with a clinical diagnosis of peanut allergy The participants were initially given a dose of 0.8mg peanut flour mixed in with food then 1.5mg 30 minutes later followed by 3mg a further 30 minutes later Those who were able to safely tolerate these very low doses – equivalent to less than 1% of a peanut – in a clinical setting were continued on a daily dose at home for two weeks Participants returned every two weeks to increase their dose under supervision until they reached a 1g dose, the equivalent of four peanuts. The participants maintained a daily dose for three months, after which 67% of them were able to consume at least 1.4g of peanut protein – the equivalent of five peanuts – without reacting. The findings are published in the journal Allergy “Living with peanut allergy is a huge burden due to the need for constant vigilance and the risk of accidental exposures,” said Hannah Hunter lead author and a specialist allergy dietitian at Guy’s and St Thomas’ NHS foundation trust “Many participants who completed the trial told us that the treatment had been life-changing and they were no longer living in fear.” Some patients took longer than others to desensitise – time on the trial ranged from eight to 14 months before the pandemic although Covid-related delays meant the process took 23 months for some participants the participants were able to continue their daily peanut consumption to remain desensitised and were advised not to consume more than their daily dose and to still carry an adrenaline EpiPen was diagnosed with a peanut allergy as a baby and said that the possibility of accidental exposure to peanuts was a source of anxiety I have four peanuts every day with my breakfast to maintain my immunity,” he said a tiny mistake could have life-threatening impacts but now I don’t have the fear that I might collapse and die from eating a takeaway.” A larger multi-centre trial would be required before the treatment could be introduced more widely but the findings suggest the approach could be as effective for adults with severe allergies chair of the national allergy study group at King’s College London said: “Conventional wisdom has been that oral immunotherapy for food is really just for children and there is clear evidence that the younger it is started that doesn’t mean that the benefits would not still be worthwhile for adults ATLANTA — The National Peanut Board (NPB) has launched “Something’s Missing,” a new promotional campaign to spotlight the absence of peanuts from K-12 cafeterias and college and university dining halls With vivid visuals and a striking narrative, the campaign uses a part-empty meal tray or to-go container to illustrate a key food item, like a peanut butter sandwich or a peanut sauce The campaign highlights the unintended consequences of blanket allergen bans that remove a nutritious affordable and culturally significant food from millions of students’ plates “The message is simple but powerful: something’s missing from foodservice menus marketing and communications manager at NPB we’re talking about access to plant-based protein good fats and an ingredient beloved across cultures This campaign helps reframe the conversation and bring best practices and compassion into decision-making at every level of food service.” Housed at NationalPeanutBoard.org/SomethingsMissing the campaign will appear at key industry conferences in trade publications and across digital platforms social media content and engaging ads tailored to both K-12 and college and university audiences Something’s Missing also encourages K-12 and college and university operators to share their stories of successfully serving peanuts while following best practices to keep students with allergies safe This initiative aligns with the Board’s broader strategy to ensure that peanuts remain a viable and visible choice in institutional dining State peanut grower organizations continue to play a crucial role in this effort working at the local level to build relationships with school nutrition directors chefs and administrators to champion smart The Something’s Missing campaign is not only a call to action but also an invitation to reimagine what inclusion really means in K-12 and campus dining By partnering with experts and elevating voices across the foodservice landscape NPB is driving forward its mission to educate For more information about the campaign, visit NationalPeanutBoard.org/SomethingsMissing WASHINGTON — Eating gradually increasing doses of store-bought home-measured peanut butter for about 18 months enabled 100% of children with peanut allergy who initially could tolerate the equivalent of at least half a peanut to consume three tablespoons of peanut butter without an allergic reaction This easy-to-implement treatment strategy could potentially fulfill an […] WASHINGTON — The Foundation for Food & Agriculture Research (FFAR) is now accepting Harvest for Health Breakthrough Crop Challenge applications Harvest for Health is accelerating the development of underutilized crops to increase the diversity of foods in the marketplace The Harvest for Health Breakthrough Crop Challenge invites applicants to submit predictive models that can screen underutilized crops to determine a […] ATLANTA — The National Peanut Board is embarking on a contemporary process for food allergy research funding The request for proposals (RFP) process is now open through August 7 Up to $250,000 will be awarded in total to qualified studies designed to advance food allergy solutions Interested applicants can find more details and submit a Letter […] — The Livestock Marketing Association is proud to announce the opening of its 2025 scholarship program application period This annual program is designed to support students who understand the vital role of agriculture and its supporting industries including the auction method of livestock marketing John Greenley: Making Rural Missouri Shine Angus Foundation Seeks Donations for Silent Auction Be sure you have your GPS enabled and try again We use cookies in order to optimize our website and improve it continuously Peanut prices in India have declined again and there is little hope of a recovery in the near future The prospect of reduced sowing for the coming season does not affect the outlook either Trade on the Indian peanut market has been limited over the past two weeks and prices are still falling Market experts currently reckon that the price declines could continue for up to eight weeks The governments of the individual federal states are gradually releasing their stocks for sale market players are also observing that demand for high-quality varieties is slowly picking up farmers will also soon increase their purchases in order to By entering a Mundus Agri Membership you can obtain the news item for free Incoterms are internationally recognized trade clauses that facilitate the trade in goods with the help of standardized contract formulas They regulate the distribution of costs and obligations and thus prevent misunderstandings and disputes They must always be agreed by both contracting parties and confirmed by signing the contract Please note that this is only a rough overview of the Incoterms. For a comprehensive description of the Incoterms, please visit the website of the International Chamber of Commerce Peanut allergy is the leading cause of pediatric emergency room visits among food allergens The allergy now affects 2% of all children A real-world study of peanut oral immunotherapy in children younger than 3 has shown the approach is both safe and effective at desensitizing children to the increasingly common food allergy The UVA Health Children’s researchers enrolled 30 peanut-allergic children in the study of what is called epOIT – Early Peanut Oral Immunotherapy The researchers cautiously and gradually increased the dose of peanut protein the children were given Sixteen children showed no adverse effects at all while 12 suffered only mild hives or rash that were easily treated with antihistamines including one due to an anaphylactic reaction occurring at home (There was no placebo group in the study.) All of the 27 children who completed the study were ultimately able to consume a “maintenance dose” of 500 mg of peanut protein per day One child even accidentally consumed about 3,000 mg of peanuts (about 40 Reese’s Pieces) and had no reaction Eight other children were able to complete a formal peanut food challenge in the allergy clinic and are now freely eating peanut multicenter clinical trials to advance what could be a game-changing new treatment for peanut allergies in very young children “Our study demonstrated that epOIT performed in younger ages – starting less than age 3 – is quite safe and effective at achieving desensitization: consumption of the equivalent of about two peanuts daily,” said researcher Jonathan Hemler a pediatric food allergist at UVA Health Children’s "About one-third of the cohort eventually were also able to achieve free consumption of peanut after passing a formal peanut food challenge in the allergy clinic Our study corroborates the findings of other published studies which show ‘the younger the better’ when starting desensitization therapy for peanut allergy.” The number of children suffering peanut allergy has grown over the last several decades and now affects approximately 2% of all kids It’s the leading cause of pediatric emergency room visits among food allergens While some children eventually outgrow the allergy That leaves the children and their families desperate to avoid accidental exposures often requiring dramatic changes in their lifestyles Routine childhood activities such as enjoying a school snack can be perilous Prior studies had suggested that peanut oral immunotherapy can desensitize children to peanuts if started early enough providing protection from an allergic reaction in case of accidental exposure But Hemler and his colleagues wanted to put that to the test in a real-world clinical setting After having detailed discussions with parents about the potential risks involved they began by giving the young trial participants 14 mg of peanut per day – less than 5% of a typical peanut The families then returned to UVA Health Children’s every two weeks to increase the dose and be observed after taking the increased dose to make sure the children were OK All the 27 participants who completed the study were eventually able to sustain the 500 mg target for daily peanut consumption – the equivalent of about two peanuts.  After consuming 500 mg of peanut protein daily for at least a year eight of the children who showed the most promising responses in their allergy testing results moved on to consume a “challenge” dose of 6,000 mg of peanut protein and their families were then told the children could eat peanuts freely but to keep peanut in their child’s diet regularly to maintain this protection The child who accidentally consumed all those Reese’s Pieces was given the same direction and none of the nine children has since had his or her peanut allergy return Hemler and his colleagues say their promising results offer important evidence that the approach is safe and effective in children ages 6 months to 3 years old They posit that starting peanut allergic children on epOIT very early in life made them more likely to become desensitized – the average age of the study participants at the start of the study was only 14 months.  the researchers are encouraged by the initial results “The allergy community needs definitive answers as to whether epOIT can possibly help induce tolerance or outgrowth of peanut allergy,” Hemler said “This would require a robust double-blinded there are ethical considerations when designing such a trial around whether giving placebo to these young children could cause harm given the findings from our study and the current published literature.” The researchers have published their findings in PAI, Pediatric Allergy and Immunology The researchers have no financial interest in the work The study was supported by Food Allergy Research and Education (FARE) To keep up with the latest medical research news from UVA, subscribe to the Making of Medicine blog Categories: All Releases Email  |  jdb9a@virginia.edu © 2025 by the Rector and Visitors of the University of Virginia CHARLOTTESVILLE, VA (CVILLE RIGHT NOW/UVA HEALTH) – UVA Health Children’s researchers have helped conduct a real-world study of peanut oral immunotherapy in children younger than 3 which shows the approach is both safe and effective at desensitizing children to the increasingly common food allergy A UVA Health release describes the researchers enrolled 30 peanut-allergic children in the study of what is called epOIT – Early Peanut Oral Immunotherapy There was no placebo group in the study.adButlerLazyLoad("2108384115404894200",100,["688449","688449","688449"],"177030"); Jay Hart is a news reporter with CvilleRightNow.com Reach him by email at jhart@charlottesvilleradiogroup.com or call 434-977-6397 UVA Alert Monday morning from self-inflicted gunshot incident The Nelson County Sheriff and The AWARE Foundation of Virginia asking help finding a missing Nelson County teen Governor Youngkin took final actions to complete the legislative session for 2025 in the General Assembly City Council Monday night considers a grant program to assist low- and moderate-income people whose home ownership in the city may be in jeopardy due to financial stress associated with costs owning that home Virginia’s standing as one of the top states in the nation for patient safety in hospital settings has again been affirmed in the Leapfrog Group Hospital Safety Grade rankings Peanut butter is a staple in everything from smoothies to sandwiches and it is just as good eaten straight from the jar But this creamy spread has some surprising talents outside the kitchen too It turns out peanut butter can be used for way more than just snacking and some of its off-label uses might actually come in handy George Washington Carver may have come up with hundreds of ways to use it but here are a few he probably didn't see coming For most of the peanut butter uses below you'll want to use a plain There's no need to spurge on fancy stuff either organic peanut butter for your next snack attack Below you'll find eight surprising ways use peanut butter for common household tasks.For more household tips, learn how to a cheeseburger in the air fryer and the worst places to put your Alexa speaker Save the cheese for happy hour snacking and smear a little pb on the trap Forget cheese -- to catch mice or rats, use peanut butter.  You can bait a mousetrap with it or just leave some goober goo on a plate: Peanut butter is a natural anticoagulant that disrupts its normal blood-clotting function As anyone who has opened a jar knows, peanut butter is naturally oily. That makes it a good emollient for buffing purses, sofas and other leather goods. Just apply a dollop to a soft cloth and wipe the leather in a circular motion until it shines.Pro tip: Peanut butter is also claimed to be great for getting scratches out of woodwork Peanut butter is rich in oil that can give hair a lustrous glow or apply the spread directly to your tresses.  If the smell of dinner is permeating every nook and cranny of your house try heating up a tablespoon of peanut butter in a pan Let it sizzle for a minute and the aroma should be replaced with a mild Peanut butter as shaving cream the natural oils in peanut butter work as an effective barrier between your skin and a razor blade (And they double as a good moisturizer.) Apply some smooth peanut butter to your face Peanut butter can also help with a squeaky hinge, stuck window sill or other household jam. (No pun intended.) Just dab a little on the stuck part and wipe it clean.It can also be used to lubricate engine valves and will get glue gum or other sticky substances out of carpet or fabric Run out of windshield wiper fluid? According to The Family Handyman just rub peanut butter on the glass and let it sit for about 10 minutes before you hose it down Trying to get our four-legged friends to dry-swallow a pill is a fool's errand Plop that thing in a gob of peanut butter and they will happily take it down the hatch.  Exposing children with peanut allergy to proteins from the legume is an approved treatment to reduce the risk of allergic reactions and now we have evidence it also works in adults By Carissa Wong Peanuts are one of the most common foods people are allergic to Adults with peanut allergy reduced their risk of reactions by eating a little peanut protein every day as part of a trial This approach is already approved in the US for children with the condition Peanut allergy occurs when the immune system mistakenly identifies proteins in the legume as a threat It responds by producing more IgE antibodies which are a vital part of the immune response but go into overdrive with allergic reactions a life-threatening reaction that can affect someone’s breathing or their heart rate Read more The new drugs preventing allergic reactions to peanuts and other foods but an intervention called oral immunotherapy was approved for children with the allergy in the US in 2020 This involves training the immune system to tolerate the allergen by exposing it to gradually increasing doses of peanut proteins However, it was unclear if the approach also worked in adults. “Most of the life of a peanut allergic individual is spent as an adult, but we’ve had no treatment to reduce their underlying reactivity to peanuts,” says Stephen Till at King’s College London “There are some grounds for suspecting that adults would be more hard to desensitise than children because your immune system is easier to modify when you’re younger.” Till and his colleagues recruited 21 adults with peanut allergy the participants were only able to eat up to an eighth of a peanut Get the most essential health and fitness news in your inbox every Saturday The team had each participant eat the protein equivalent of one 40th of a peanut every day for two weeks This dose was slightly increased every two weeks for several months until they could safely and consistently eat the protein equivalent of four large peanuts every day for a month Three participants dropped out of the study due to allergic reactions, while three others left due to reasons unrelated to the treatment. “This dropout number is acceptable for this kind of treatment,” says Cezmi Akdis at the Swiss Institute of Allergy and Asthma Research The remaining 15 participants took part in an allergy test where they ate increasing doses of peanut protein under the researchers’ supervision All but one of them was able to eat the equivalent of five peanuts without having an allergic reaction In another part of the experiment, the team analysed blood samples collected from the participants before and after they received oral immunotherapy. This revealed that the intervention caused them to have higher levels of IgG antibodies which counteract the effects of IgE antibodies Inside the new therapies promising to finally beat autoimmune disease coeliac disease and lupus are all caused by the body attacking itself But new therapies that reset the immune system could offer lasting help “This approach could mean that adults with peanut allergy can be relieved of the anxiety of eating food contaminated with peanuts.” But this was a relatively early-stage trial and larger ones are needed to verify the results and establish how long the protection lasts “I’d expect you’ll need to take daily or regular doses of peanuts in the long term to maintain the tolerance to the allergen,” says Akdis so I think people affected by peanut allergies may well be fine adhering to this sort of method.” Speak to your doctor before seeking new treatments for medical conditions Allergy DOI: 10.1111/all.16493 grown peanuts is important to the industry there are concerns about those exports with the tariff talks This legume can reduce cholesterol and help with weight loss and healthy blood sugar levels We tend to think of peanuts as nuts — it’s in the name Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy “Peanuts are popular in many cuisines worldwide and in plant-based diets,” says registered dietitian Julia Zumpano as well as several vitamins and minerals.” Zumpano breaks down peanut health benefits An ounce of peanuts also provides these key nutrients: Peanuts are a nutrient-dense food that offer some specific health benefits Zumpano shares the top reasons why peanuts are good for you may help reduce the risk of a wide range of chronic diseases,” says Zumpano Peanuts are packed full of plant compounds and mineral antioxidants “Phytosterols are compounds found in plants and they’re similar in structure to cholesterol they block the absorption of cholesterol in your digestive system which can lower cholesterol levels,” explains Zumpano which can make you feel full quicker and longer,” notes Zumpano Peanuts might even make weight loss more pleasant if you’re not a fan of low-fat diets, according to a study of people cutting calories to lose weight Those who ate 1 ounce of peanuts before two meals each day lost around the same amount of weight as those on a low-fat diet All nuts help keep blood sugar steady, as they’re rich in fiber and protein and low in carbs. But what’s going on at a cellular level? A review of 40 different experiments found that eating peanuts and tree nuts may improve your insulin sensitivity This means your body can use insulin more effectively But consuming peanuts isn’t likely to lower blood sugar directly regularly eating peanuts is more likely to help prevent blood sugar problems in the long run “Normal blood sugar levels are a cornerstone to good health and lowering your risk of many chronic diseases,” says Zumpano Peanut butter is easily the most popular of all the nut butters peanut butter has most of the same health benefits as peanuts,” reports Zumpano popular brands of peanut butter also contain added sugar and salt which makes peanut butter less healthy than plain peanuts Peanut allergies are common This allergy response happens when your immune system mistakenly identifies the proteins in peanuts as harmful substances These allergic reactions can be severe and even life-threatening for some people Anyone with a peanut allergy should avoid peanuts peanut butter and any foods that contain them this green-tinged nut can help with gut health and cholesterol levels These nuts are packed with healthy monounsaturated fat Fill your nutrient gaps with smart nut picks What you need to know about the hidden risks healthy nutrition plan is just as important as staying consistent with your exercise routine sleep can be tough — propping yourself up or sleeping on your side may help If you fear the unknown or find yourself needing reassurance often you may identify with this attachment style If you’re looking to boost your gut health This website is using a security service to protect itself from online attacks The action you just performed triggered the security solution There are several actions that could trigger this block including submitting a certain word or phrase You can email the site owner to let them know you were blocked Please include what you were doing when this page came up and the Cloudflare Ray ID found at the bottom of this page Dan May 1, 2025 Peanuts Approval has been received for use of a product by peanut growers Almost six months after the seizure and death of internet star Peanut the Squirrel sparked massive public outrage lawmakers and others are supporting a proposed new law they say would prevent similar incidents in the future traveled to Albany this week to join legislators and animal welfare activists in support of "Peanut's Law: Humane Animal Protection Act," which has sponsors in both the Assembly and state Senate A Senate version of the bill is sponsored by Democrat Jessica Scarcella-Spanton Read the full article here. FIND YOUR SEATSPROMOTIONS 2025 – The Chihuahuas are honoring the 75th anniversary of PEANUTS™ with a game-worn jersey auction and Fireworks Spectacular as part of a six-game homestand that kicks off tonight versus the Las Vegas Aviators (Oakland A’s affiliate) Fans are invited to join the festivities on Saturday as the Chihuahuas take the field in limited-edition Peanuts-themed jerseys The jersey features PEANUTS™ characters in comic-book style drawings alongside the signature Chihuahuas wordmark in yellow Paying tribute to Charlie Brown’s iconic outfit the jersey sleeves are bright yellow with the classic black zig-zag trim The online jersey auction is LIVE NOW and concludes at the final out of the seventh inning on Saturday Fans interested in bidding can participate by texting the word “BID” to 915-600-6677 The celebration will culminate in a PEANUTS™-themed Fireworks Spectacular lighting up the night sky following the game Fans are encouraged to arrive early and enjoy themed promotions honoring one of the most beloved comic strips of all time The series also features Autism & Sensory Awareness Night tonight Bark Back at Cancer presented by The Hospitals of Providence on Wednesday Fans can also enjoy a midweek matinee game on Wednesday with a 12:05 p.m and there are food and beverage specials Tuesday through Thursday visit epchihuahuas.com or follow the Chihuahuas on social media APRIL 8 | GATES: 5:30PM | FIRST PITCH: 6:35PM Game Highlight: Autism & Sensory Awareness Night presented by Gozo’s Ice Cream Join us for a fun and inclusive night at Southwest University Park as we celebrate Autism & Sensory Awareness Night with the Chihuahuas Enjoy a fan-friendly environment designed with accessibility in mind To help create a comfortable experience for all guests the public address volume will be lowered to better accommodate those sensitive to loud sounds Complimentary sensory bags will also be available (must be returned) at the Guest Services Booth This special night is dedicated to providing a safe Game Highlight: Taco Tues & Brews presented by Cazadores Game Highlight: Savings for Those Who Serve and government officials may receive up to 25% savings on tickets by purchasing tickets via GovX.com APRIL 9 | GATES: 11:00AM | FIRST PITCH: 12:05PM Enjoy a midweek break at a Chihuahuas midweek matinee game make the Chihuahuas game the perfect backdrop for a fun and relaxing afternoon Game Highlight: Mature Munchies presented by AARP Patrons can visit the promotions booth behind Section 112 to receive their vouchers APRIL 10 | GATES: 5:30PM | FIRST PITCH: 6:35PM Game Highlight: Thrifty Thursday presented by Speaking Rock Giveaway: Bark Back at Cancer presented by The Hospitals of Providence Join the Chihuahuas for Bark Back at Cancer Night an evening dedicated to raising awareness in the fight against cancer Show your support as we unite to honor survivors APRIL 11 | GATES: 5:30PM | FIRST PITCH: 6:35PM Giveaway: Reversible Jersey Giveaway presented by Cesar Ornelas Law Limited-edition reversible jerseys will be given away to 1,500 fans through the gates Limit is one per person while supplies last Game Highlight: Fetch the Fun Friday presented by KSII FM APRIL 12 | GATES: 5:30PM | FIRST PITCH: 6:35PM Game Highlight: 75th Anniversary of PEANUTS™ Celebration The El Paso Chihuahuas are celebrating the 75th anniversary of PEANUTS™ with a special themed night at the ballpark Fans can look forward to limited-edition game-worn jerseys featuring beloved Peanuts characters and Charlie Brown’s iconic zig-zag design a postgame Peanuts-themed Fireworks Spectacular Game Highlight: PEANUTS™ Game-Worn Jersey AuctionDon’t miss your chance to bid on the one-of-a-kind Peanuts jerseys by texting “BID” to 915-600-6677 starting Tuesday at noon through the final out of the seventh inning on Saturday Winners who have paid in full can come down to the field post-game to receive the jersey from the respective player Get ready for an electrifying night at the ballpark The Chihuahuas will light up the sky with a Fireworks Spectacular choreographed to the music of PEANUTS™ for an unforgettable experience APRIL 13 | GATES: 11:00AM | FIRST PITCH: 12:05PM Who doesn't love America's Pastime & an early afternoon in the sun with friends and fun Join the Chihuahuas for a paw-some celebration as we celebrate Chico’s birthday It's the 75th Anniversary of Peanuts and we are celebrating with special themed jerseys Specialty Peanuts Jerseys:  A silent auction for the game-worn jerseys will take place in the arena lobby  Bidding ends at the start of the 3rd period  Proceeds from the auction will benefit the Boys & Girls Club and the Blue Bucket Brigade Peanuts + Komets Apparel: The Komets are teaming up with Peanuts for a special apparel selection as part of Peanuts Night on March 9th which will be available online and at the game will feature custom original art of Snoopy and the Peanuts gang across a selection of shirts and sweatshirts for children and adult lines.   Meijer Family Nights + Post Game Skate:  Visit the Memorial Coliseum Ticket Office and get 4 Upper Arena Tickets for just $58! Also bring your skates to go out on the ice after the game Sign up for our email newsletter to be the first to know about news and upcoming games Spanish scientists reveal that snacking on whole peanuts could help protect your cells’ youth opening new doors to harnessing everyday foods for healthier aging Study: Unveiling the Impact of Peanut Consumption on Telomere Length in Young and Healthy Individuals: Insights from the ARISTOTLE Study: A Randomized Clinical Trial Image Credit: Rolling Stones / Shutterstock Did you know that telomeres, the protective caps at the ends of our chromosomes, shorten as we age, potentially accelerating aging and disease? In a recent study published in the journal Antioxidants, a research team in Spain explored whether consuming peanuts, which are rich in antioxidants to further our understanding of the potential role of diet in slowing down cellular aging Increases in monounsaturated fat and m-coumaric acid intake were linked to longer telomeres in the study’s analysis diets rich in antioxidants may help reduce the rate of telomere attrition Peanuts are a common dietary source of several antioxidant compounds These compounds may neutralize reactive oxygen species (ROS) and reduce inflammation While some observational studies suggest an association between higher nut intake and longer telomeres evidence from clinical trials remains limited and inconsistent Participants who ate skin-roasted peanuts saw no cases of accelerated telomere shortening while 22% of the peanut butter group and 38% of the control group experienced significant shortening over six months parallel-design clinical trial was conducted over 6 months to investigate whether daily peanut consumption could impact telomere length in saliva samples of healthy young adults A total of 63 participants were initially recruited but 5 were excluded due to incomplete data leaving 58 participants aged 18–33 years for analysis Participants were randomly assigned to one of three groups: 25 g/day of skin-roasted peanuts (SRP) or 32 g/day of a control butter made from peanut oil (CB) Dietary intake was tracked using a validated 151-item food frequency questionnaire at baseline and after 6 months Physical activity was assessed via the Minnesota Leisure-Time Physical Activity Questionnaire Telomere length was measured using quantitative PCR (qPCR) on saliva-derived DNA expressed as a telomere-to-single-copy gene (T/S) ratio researchers analyzed self-reported dietary records and urinary biomarkers linked to peanut intake such as resveratrol metabolites and coumaric acids Participants were instructed to avoid other nuts Fiber intake spiked by 12% in the skin-roasted peanut group suggesting whole nuts’ structural integrity may play a role in gut health linked to telomere preservation the group consuming skin-roasted peanuts (SRP) showed a modest but statistically significant increase in telomere length compared to the control group (mean difference: 0.53; 95% CI: 0.01 peanut butter (PB) consumption did not produce significant changes relative to the control 0% of SRP consumers experienced accelerated telomere shortening (defined as a reduction in length below the 20th percentile) compared to 22% in the PB group and 38% in controls may promote gut microbiota-derived short-chain fatty acids (SCFAs) which were previously linked to lower cortisol and depression biomarkers in the same trial but the researchers noted that unsalted peanuts might be preferable for older populations due to cardiovascular risks A key limitation was the relatively small sample size (58 participants) and lack of a peanut-free control group While the SRP group showed higher baseline HDL cholesterol levels (1.73 mmol/L vs this imbalance was not fully addressed in the analysis While the 6-month intervention provided insights and longer-term studies are needed to confirm effects The study suggests that daily consumption of skin-roasted peanuts for 6 months may slow telomere shortening in young likely due to their high monounsaturated fat (MUFA) content and bioactive compounds like m-coumaric acid Peanut butter did not show similar benefits possibly due to processing-related changes in fiber structure or nutrient bioavailability "These findings highlight the importance of whole foods over processed alternatives in promoting cellular health," the authors noted They emphasized the need for longer trials in diverse populations Posted in: Child Health News | Men's Health News | Medical Science News | Medical Research News | Women's Health News Chinta Sidharthan is a writer based in Bangalore Her academic background is in evolutionary biology and genetics and she has extensive experience in scientific research in evolutionary biology from the Indian Institute of Science and is passionate about science education she explored the origins and diversification of blindsnakes in India as a part of which she did extensive fieldwork in the jungles of southern India She has received the Canadian Governor General’s bronze medal and Bangalore University gold medal for academic excellence and published her research in high-impact journals Please use one of the following formats to cite this article in your essay Peanuts pack a punch for youth: study finds cellular benefits 2025 from https://www.news-medical.net/news/20250415/Peanuts-pack-a-punch-for-youth-study-finds-cellular-benefits.aspx "Peanuts pack a punch for youth: study finds cellular benefits" <https://www.news-medical.net/news/20250415/Peanuts-pack-a-punch-for-youth-study-finds-cellular-benefits.aspx> https://www.news-medical.net/news/20250415/Peanuts-pack-a-punch-for-youth-study-finds-cellular-benefits.aspx Cancel reply to comment Learn how experts are advancing benzodiazepine analysis and detection using insights from the lab discusses how he is addressing today’s medical challenges using the technology of the future Explore how the Radian ASAP mass spectrometer is being used to streamline and enhance seized drug screening you can trust me to find commercial scientific answers from News-Medical.net please log into your AZoProfile account first Registered members can chat with Azthena, request quotations, download pdf's, brochures and subscribe to our related newsletter content A few things you need to know before we start Read the full Terms & Conditions Please enable JS and disable any ad blocker Cartoonist Charles Schulz poses with a sketch of Snoopy in his office in Santa Rosa who died shortly after his retirement in 2000 featuring beloved characters Charlie Brown Schulz said he didn't think it would last long "Peanuts was originally sold as a space saving comic strip at the time It was probably the smallest comic strip around," Schulz told Morning Edition in 1995 "I've always said there was no room for adults because if they had stood up they would have bumped their heads on the top of the panel." Eventually, the Peanuts gang was everywhere. T-shirts, lunchboxes, Macy's Thanksgiving Day Parade balloons. NASA even named the two modules of the Apollo 10 spacecraft after Peanuts characters Charlie Brown and Snoopy. The craft flew on a mission to orbit the moon in 1969 curator of the Charles Schulz Museum in Santa Rosa said the Peanuts comic strip had 100 million readers at its peak Key to the strip's popularity was that the characters expressed emotion "The newspaper comic strips that Schulz grew up reading were nothing like this," Clark said "Schulz was so revolutionary in being so emotionally honest." was derived from his own childhood growing up in Minneapolis in the 1920s "There were episodes in our neighborhood where there were some cruel children and it's very difficult out there in the playground to survive," he told NPR Clark said the museum is seeing record-high attendance these days. From June 2023 to June 2024, the museum reported having 100,000 visitors – the most ever in its 22-year history Clark credits social media for the comic strip's latest bump in popularity. In recent years, Snoopy sparked a Gen Z frenzy as teens and other youth scoured stores for merchandise featuring the beagle the character's official TikTok account following ballooned they're using it to make memes and they're able to use it in fashion and design – and they're doing fun stuff with it," Clark said "And it's really interesting to see where this creative drive and this influence and inspiration will take everyone." Last year, Apple TV+ began streaming a special about the origin of Franklin the first Black character on the Peanuts comic strip A new Peanuts film that began production last year is also in the works at Apple TV+ Reena Advani edited the radio version of this story Become an NPR sponsor More » More » More » More » More » More » Peanut is one of the most common food allergies It often begins in childhood and usually lasts for life NIH-supported studies over the past few decades have led to important advances and improved treatment options for many people with peanut allergies Most such treatments were tested in kids who are highly sensitive to peanuts unable to tolerate even the equivalent of a half peanut These treatments can raise the safe threshold before a reaction Less has been known about effective treatments for the estimated 800,000 children in the U.S These children can tolerate eating half a peanut or more Sicherer and Julie Wang of the Icahn School of Medicine at Mount Sinai designed a clinical trial at-home treatment strategy could help kids with high-threshold peanut allergy tolerate more peanut protein They were randomly assigned to either test the new treatment strategy or continue avoiding peanut children in the treatment group received a minimum daily dose of 1/8 teaspoon of store-bought peanut butter Doses were gradually increased and tested under medical supervision every eight weeks daily doses had reached about the equivalent of 1 tablespoon of peanut butter participants in both the treatment and avoidance groups underwent a medically supervised feeding test to assess how much peanut they could eat without an allergic reaction The researchers found that all 32 treated children who participated in the oral food challenge could tolerate 9 grams of peanut protein That’s equivalent to about two and a half tablespoons of peanut butter only three of the 30 kids who underwent the oral food challenge in the avoidance group (10%) could tolerate that much peanut protein The treatment group’s daily at-home doses of peanut butter were well tolerated None of the treated children needed epinephrine to ease severe allergic reactions at home although one needed it for a reaction during a medically supervised dose increase To assess the potentially lasting effects of treatment kids in the treatment group continued to eat at least 2 tablespoons of peanut butter weekly for 16 weeks They then avoided peanut for eight weeks and returned for a final food challenge The researchers found that 26 of the 30 treated children (86.7%) were still able to tolerate 9 grams of peanut protein and effective pathway for allergists to treat children with peanut allergy who can already tolerate the equivalent of at least half a peanut considered a high-threshold peanut allergy,” Sicherer says “My hope is that this study will eventually change practice to help these children and encourage additional research that includes this approach for more foods.” References: Peanut Oral Immunotherapy in Children with High-Threshold Peanut Allergy. Sicherer SH Funding: NIH’s National Institute of Allergy and Infectious Diseases (NIAID) and National Center for Advancing Translational Sciences (NCATS) Therapy boosts peanut tolerance in allergic kids Creating an artificial sense of touch Scratching and allergic skin inflammation Subscribe to get NIH Research Matters by email New biomarker tracks cognitive decline in Alzheimer’s disease Midlife eating patterns tied to health decades later Radiation from CT scans and cancer risks Research in Context: Can we slow aging? Sex-specific pain suppression by immune cells Assistant Editors: Vicki Contie and Brian Doctrow NIH Research Matters is a weekly update of NIH research highlights reviewed by NIH’s experts. It's published by the Office of Communications and Public Liaison in the NIH Office of the Director NIH…Turning Discovery Into Health® U.S. Department of Health and Human Services It’s (almost) the most wonderful time of the year Apple TV+ will provide special free streaming windows for nonsubscribers to enjoy the iconic Peanuts holiday specials from Mendelson/Melendez Productions and Peanuts Worldwide October 20; “A Charlie Brown Thanksgiving,” available Saturday November 24; and “A Charlie Brown Christmas,” available Saturday Subscribers can watch these specials anytime The Apple TV+ lineup for Peanuts classics holiday fare (in chronological order): Join the Peanuts gang for a timeless adventure as Charlie Brown preps for a party Snoopy sets his sights on the Red Baron and Linus patiently awaits a pumpkin patch miracle Peppermint Patty invites everyone to Charlie Brown’s for Thanksgiving even though he is already going to celebrate at his grandmother’s Snoopy decides to cook his own version of a Thanksgiving meal with help from his friends feeling down about the commercialism of Christmas Lucy recruits Charlie Brown to be the director of the gang’s holiday play Can he overcome his friends’ preference for dancing over acting find the “perfect” tree and discover the true meaning of Christmas and is available to watch across all of a user’s favorite screens Apple TV+ became the first all-original streaming service to launch around the world and has premiered more original hits and received more award recognitions faster than any other streaming service in its debut documentaries and series have earned 516 wins and 2,310 award nominations and counting including multi-Emmy Award-winning comedy “Ted Lasso” and historic Oscar Best Picture winner “CODA.” Apple TV+ is available on the Apple TV app in over 100 countries and regions, on over 1 billion screens, including iPhone, iPad, Apple TV, Apple Vision Pro, Mac, popular smart TVs from Samsung, LG, Sony, VIZIO, TCL and others, Roku and Amazon Fire TV devices, Chromecast with Google TV, PlayStation and Xbox gaming consoles, and at tv.apple.com for $9.99 per month with a seven-day free trial for new subscribers customers who purchase and activate a new iPhone Mac or iPod touch can enjoy three months of Apple TV+ for free.* Snoopy has had multiple personas over the years including the Red Baron, Beagle Scout and Joe Cool, he now has another one to add to the list, Joe Kind, thanks to Starbucks The iconic beagle pal of the "Peanuts" gang, has made his way onto the coffee company's reusable coffee cup and other merchandise as part of a "kindness, coffee, and community" campaign that spans across the United States and the globe mug and stainless-steel tumbler with "Peanuts"-inspired designs on them and will only be available for purchase at participating Starbucks stores for a limited time Here's how you can get your hands on the limited edition Starbucks and Snoopy items You may have heard talk about a free reusable Starbucks Snoopy cup it's not available to United States customers some global Starbucks Rewards customers can get their hands on a free reusable coffee cup North American customers of the widely popular coffee company don't always get all of the same promotions that others have While you can't get the free reusable coffee cup this go around Snoopy and the "Peanuts" gang merchandise is available for a limited time at Starbucks across the country The Joe Kind line is part of a three piece merchandise set that includes Snoopy "Peanuts Love Cold Cup": A 24-ounce cold cup shows Joe Kind Snoopy listening as his bestie Woodstock shares a story in bird language The cup features a double-wall construction and a flat lid with a straw."Peanuts Joe Kind Snoopy Stainless Steel Tumbler": A 16-ounce stainless steel tumbler that has Joe Kind Snoopy and Woodstock soaking in all of the love The double-wall vacuum insulated tumbler keeps drinks hot for 1.5 hours and cold for 4 hours."Peanuts Friendship Ceramic Mug": A 14-ounce Peanuts mug showcases all of the Peanuts pals hanging out and having a good time.How much are Snoopy cups from Starbucks?The drinkware ranges from $17.95 to $29.95 Want to add one of the Joe Kind items to your coffee cup collections Check out your local Starbucks to see if the limited edition items area available Find you local store at starbucks.com. Metrics details Peanut (Arachis hypogaea L.) is an important oilseed and food legume crop with seed size and weight being critical traits for domestication and breeding genomic rearrangements like structural variations (SVs) underlying seed size and weight remain unclear Here we present a comprehensive pangenome analysis utilizing eight high-quality genomes (two diploid wild two tetraploid wild and four tetraploid cultivated peanuts) and resequencing data of 269 accessions with diverse seed sizes 22,232 distributed and 5,643 private gene families The frequency of SVs in subgenome A is higher than in subgenome B We identified 1,335 domestication-related SVs and 190 SVs associated with seed size or weight a 275-bp deletion in gene AhARF2-2 results in loss of interaction with AhIAA13 and TOPLESS reducing the inhibitory effect on AhGRF5 and promoting seed expansion This high-quality pangenome serves as a fundamental resource for the genetic enhancement of peanuts and other legume crops To optimize the exploration of genomic variations it is important to have access to high-quality genomic resources across various populations of peanuts Developing a pangenome can identify missing or unannotated genes in the current reference genome aiding in the discover of genes linked to yield especially for large-sized variations such as SVs we generated a comprehensive pangenome for both wild and cultivated peanuts two tetraploid wild species and four tetraploid cultivated species We assessed the genome-wide diversity of 269 peanut accessions and conducted SV-GWAS to investigate agronomic traits related to yield Our analysis of the peanut pangenome showed significant genomic variations from breeding and highlighted trait-related variations affecting seed size and weight providing a valuable resource for future improvements AABB landrace and AABB improved) of peanut including 269 peanut accessions with different seed sizes Relationships of peanut accessions are illustrated using a phylogenetic tree based on subsampling 100,000 SNPs The labeled accessions were used for downstream high-quality genome assembly or pangenome construction Seed size (seed weight and length) differs significantly across four peanut populations P values were calculated by two-tailed Student’s t-test PCA based on SNPs from the A subgenome (d) and the B subgenome (e) Summary of nucleotide diversity (π) and population divergence (FST) in the A subgenome (f) and B subgenome (g) between peanut populations Results of population structure analysis using ADMIXTURE clustering when K = 8 landrace and improved accessions is highlighted in a dashed box Source data US10 and so on) and several landrace accessions (SA080 SA117 and so on) were clustered into one group and shared more than 35% proportions with their ancestry BB accessions (H104 suggesting that cultivated accessions likely originated from wild allotetraploid accessions Comparison of pods from representative diploid Possible ancestry and evolution of cultivated peanuts Gene family PAVs in representative accessions Pan-core gene family curve in representatives n = 100 (iterations of random sampling without replacement) Fitting of power law model of new gene family (n) and sample (N) with n = kN−a Number and percentage of core (eight of eight) distributed (two of eight to six of eight) and private (one of eight) gene members in representative accessions and private gene family members in the A and B subgenomes (i) Pfam enrichment analysis of distributed and private gene members in the super-large pod accession ZP06 PAV of genes with the domain PF00931 (NB-ARC domain) present in the A subgenome The white number in the boxes is the hit count of protein–genome alignment which is unlike the strict standard in gene annotation Phylogenetic tree of genes in the family OG0025534 based on multiple sequence alignment P values were calculated by two-tailed Student’s t-test (b Plot of a nucleotide-binding oligomerization domain-like receptor (NLR) gene with both large SVs (red) and small variants (SNPs and indels) (blue) SVs in the A and B subgenomes of representative accessions Distribution of SVs (the circles from outer to inner are nonredundant insertions (INS) inversions (INV) and translocations) in chromosomes insertions and inversions in the A and B subgenomes Sizes of insertions in promoter and exon regions Repeat content of insertions in promoter and exon regions Expression of single-copy genes with SVs in promoter and exon regions Fragments per kilobase of transcript per million mapped fragments; MITE Miniature inverted repeat transposable elements; NS Number of insertions and deletions from diploids to tetraploid in the A and B subgenomes Enriched KEGG pathways for genes with SVs in the A and B subgenomes of ZP06 An allele of NDH16G00520 (Snakin-2) with a 214-bp insertion has higher expression levels in flowers and fruits than the allele without the insertion NDH14G21970 (glutamine-dependent NAD(+) synthetase) with a 7.9-kb deletion has strong evidence of supported WGS A 1.2-kb insertion in NDH05G28200 (glycosyl transferase) divides it into two genes A 1.7-kb deletion in NDH18G35100 (enhanced disease susceptibility 1) and NDH18G35110 (γ-aminobutyric acid GABA permease) generated two truncated genes with different protein sequences Major genomic regions with evidence of selective sweeps during the evolution of landrace accessions from wild accessions (a) and during the evolution of improved accessions from landrace accessions (b) nucleotide diversity ratio (πW/πL or πL/πI) and XP-CLR tests were used for selection analysis Regions with evidence of selection (top 5% for at least two metrics) are highlighted Different SVs from two populations were used for searches of SV-related genes SV-related genes and SV exon-related genes under selection in the A (sub-A) and B subgenomes (B-sub) Pfam enrichment analysis of genes and SV-associated genes with evidence of selection Repeat overlap with SVs of selection in the A and B subgenomes A 629-bp deletion in CRK26 (NDH09G29320) from a CRK gene cluster at chr and genotyping of the population for CRK26 genes with (red) or without a deletion (steel blue) A 27.7-kb deletion in an IRK gene (NDH10G19410) from an IRK gene cluster at chr 10 from haplotype assembly and long-read alignment expression level of seed (middle) from various accessions and expression level of root from accession NDH108 with bacterial wilt infection (right) in the tandem unit of pod size genes NTF6 (NDH13G04110/NDH13G04130/NDH13G04150 mediator of RNA polymerase ll transcription subunit 36a) and disease-resistant related genes FBRL2 (NDH13G04100/NDH13G04120/NDH13G04140 protein kinase superfamily protein) at chr Graph-based SV-GWAS using genotype (SVs and indels from Minigraph-Cactus) and phenotype (seed weight) data from resequencing accessions Horizontal lines represent the significant threshold (P = 1 × 10−3 Gene structure of AhCKX6 and location of the insertion landrace and improved peanut accessions with the two haplotypes of AhCKX6 Box plots for seed length and 100-seed weight according to the genotype of the SV in AhCKX6 The numbers of accessions with the HapI and HapII genotypes are 61 and 183 Evolution of CKX6 proteins in different plant lineages Phylogenetic analysis of CKX proteins from various plant lineages using the alignment of 25 full-length CKX6 protein sequences The ancestral CKX gene sequence evolved in the kingdom Plantae along with the diversification into monocot and eudicot plant species >150 Ma Expression levels of AhCKX6 in different tissues of HapI and HapII The expression level of AhCKX6 was higher in HapI than in HapII in developing seeds Seeds of HapII accessions contain more cytokinins than those of HapI accessions Model showing the mechanism by which AhCKX6 regulates peanut seed size P values were calculated by two-tailed Student’s t-test (f Graph-based SV-GWAS using genotype (SVs from Assembly and Read) and phenotype (seed length) data from resequencing accessions Horizontal lines represent the significance threshold (P = 1 × 10−3 Box plots for seed length and 100-seed weight according to the genotype of the SV in AhARF2-2 Relative expression levels of AhARF2-2 in different tissues Expression pattern of ARF2-2 after NAA treatment Bimolecular fluorescence complementation (BiFC) assay of the interaction of AhARF2-2 Y2H of the interaction of AhARF2-2 with AhIAA13 (h) or AhTPL (i) BD-T7-Lam (pGBKT7-Lam)/AD-T7-T (pGADT7-T) was used as the negative control and BD-T7-53 (pGBKT7-53)/AD-T7-T was used as the positive control Dual-luciferase assay in tobacco leaves expressing LUC Renilla luciferase (REN) was used as the internal control to normalize values in each assay Overexpression of AhARF2-2HapI/HapII in Arabidopsis thaliana Relative expression levels of overexpression (OE) and wild-type (Col) Arabidopsis seed length (o) and seed width (p) between the OE and Col plants Model of AhARF2-2 determining peanut seed size: AhIAA13 binds AhARF2-2 via the AUX/IAA domain P values were calculated by two-tailed Student’s t-test (d our comprehension of the molecular mechanisms and evolutionary factors influencing peanut pod size and weight remains limited we developed comprehensive peanut pangenomes by integrating data from eight high-quality peanut genomes and 269 resequenced accessions This resulted in an extensive resource of genomic variations that contribute to key agronomic traits in peanuts The newly constructed pangenomes and identified variations enhance our understanding of the genetic basis underlying traits such as seed size and weight and will facilitate advancements in crop science and peanut breeding thereby potentially improving global food security Our analysis revealed that combining assembly-based and read-based methods using long-read sequencing data improves the identification of SVs in plant genomes a significant observation is that most insertion SVs are associated with LTR retrotransposons and DNA transposons Our study revealed that SVs could influence gene expression functional dynamics and uneven domestication between the two subgenomes Our research suggested that resistance was compromised as yields increased during peanut domestication SV-GWAS identified two significant regions potentially related to seed size and weight Subsequent experiments confirmed that SVs in these genes influenced seed size and weight an SV in the 3′-UTR of the AhCKX6 gene on chr encodes an auxin response factor and negatively regulates seed size our research still has the limitation on the sample size of tetraploid wild peanuts in population selection owing to the specificity of Arachis monticola acting as an intermediate between cultured and wild peanut we have developed an extensive dataset comprising high-quality reference genomes pangenomes and significant genomic variations elucidating the influence of SVs on critical traits This study furnishes a genetic resource for the identification of functional genes associated with yield and disease resistance offering valuable tools for breeding and crop enhancement for peanut as well as other polyploid species All 269 analyzed accessions (two accessions were previously published and others were newly sequenced) were collected from major peanut-growing regions which are currently one of the most complete and representative collections worldwide were used to analyze the major haplotype of the candidate gene related to the seed traits Plant DNA was extracted using the Plant DNA Extraction Kit (catalogue number SM262; Seven) Peanut seedlings were grown in pots in a growth chamber set to 28 °C with a 16 h light and 8 h dark photoperiod and ~60% relative humidity Experiments were conducted when the seedlings reached the four-leaf stage All Arabidopsis thaliana wild-type and transgenic plants were from the Columbia (Col-0) ecotype background Arabidopsis thaliana Col-0 plants and tobacco (Nicotiana benthamiana) plants were grown in pots in a growth chamber at 23 °C with a 16 h light and 8 h dark photoperiod and ~60% relative humidity The FPKM was used to estimate the gene expressions Windows filtered with at least two metrics were considered as domestication-sweep regions NDH108 was cultivated using the hydroponic method (14 h light and 10 h dark photoperiod) seedlings were inoculated with Ralstonia solanacearum (strain number 180731-1) provided by the Institute of Plant Protection Henan Provincial Academy of Agricultural Sciences We performed RNA-seq of roots in NDH108 with bacterial wilt infection 12 and 24 h) of three independent experiments in replicates The analysis process of raw reads was the same as described in the section ‘Gene expression analysis’ Fluorescence images of transiently infected tobacco leaf subepidermal cells were captured utilizing laser scanning confocal microscopy (catalogue number LSM710 Cytokinin measurements were performed by Wuhan Metware Biotechnology Co. utilizing seeds from the Amon and ZP06 varieties approximately 15 days following the peg’s penetration into the soil The AhGRF5 (Arahy.V829EQ) promoter was integrated into the pAbAi vector The recombinant plasmid pAbAi-AhGRF5 was digested with the restriction enzyme BstBI (catalogue number R0519V New England Biolabs) and transferred into the Y1H yeast strain and tested on SD/-Ura medium (catalogue number PM2271 Coolaber) with different concentrations of aureobasidin A The CDS of AhARF2-2HapI and AhARF2-2HapII were cloned into the pGADT7 and transferred into the Y1H yeast strain tested on SD/-Leu medium (catalogue number PM2201 Coolaber) with 200 ng ml−1 of aureobasidin A The CDSs of AhARF2-2HapI and AhARF2-2HapII were cloned into the N-terminal half of yellow fluorescent protein (nYFP) The CDSs of AhIAA13 and AhTPL were cloned into the C-terminal half of YFP (cYFP) to generate HapI-nYFP The appropriate pairs of constructs (AhTPL-cYFP and HapI-nYFP; AhTPL-cYFP and HapII-nYFP; AhIAA13-cYFP and HapI-nYFP; AhIAA13-cYFP and HapII-nYFP) were infiltrated into N benthamiana leaves via Agrobacterium-mediated transient infiltration and detected by laser scanning confocal microscopy (catalogue number LSM710 MDB4JZ) and AhTPL (Arahy.UFRA39) CDSs were cloned into pGBKT7 vector (bait vector) These recombinant vectors were transformed into the Y2H yeast strain The bait vectors pGBKT7-53 (BD-T7-53) and pGBKT7-Lam (BD-T7-Lam) serving as positive and negative controls respectively were cotransformed with the prey vector pGADT7-T were grown on deficient medium: lacking tryptophan and leucine (SD/-Trp/-Leu; catalogue number PM2221 tryptophan histidine and adenine (SD/-Leu/-Trp/-His/-Ade; catalogue number PM2221 The statistical analyses were mostly performed in R (v.4.0.2) For biochemical and molecular biology analysis at least three individuals were mixed in each sample with three biological replicates Standard deviations and P values were calculated using two-tailed Student’s t-test and analysis of variance Further information on research design is available in the Nature Portfolio Reporting Summary linked to this article Peanut (Arachis hypogaea L.): a prospective legume crop to offer multiple health benefits under changing climate The genome sequences of Arachis duranensis and Arachis ipaensis the diploid ancestors of cultivated peanut Study of evolution of cultivated peanut through crossability studies among Arachis ipaënsis Fine-mapping of a wild genomic region involved in pod and seed size reduction on chromosome A07 in peanut (Arachis hypogaea L.) Multi-omics profiling identifies candidate genes controlling seed size in peanut Transcriptome analysis and gene expression profiling of the peanut small seed mutant identified genes involved in seed size control Comparative transcriptomics analysis of developing peanut (Arachis hypogaea L.) pods reveals candidate genes affecting peanut seed size Global transcriptome and co-expression network analyses revealed hub genes controlling seed size/weight and/or oil content in peanut Fine mapping of qAHPS07 and functional studies of AhRUVBL2 controlling pod size in peanut (Arachis hypogaea L.) Nested-association mapping (NAM)-based genetic dissection uncovers candidate genes for seed and pod weights in peanut (Arachis hypogaea) The genome sequence of segmental allotetraploid peanut Arachis hypogaea yields insights into genome evolution and oil improvement Genome of an allotetraploid wild peanut Arachis monticola: a de novo assembly The genome of cultivated peanut provides insight into legume karyotypes polyploid evolution and crop domestication A near complete genome of Arachis monticola Genomic variation in 3,010 diverse accessions of Asian cultivated rice Pan-genome of wild and cultivated soybeans Long-read sequencing of 111 rice genomes reveals significantly larger pan-genomes Pan-genome storage and analysis techniques Advances in Arachis genomics for peanut improvement A genomic variation map provides insights into peanut diversity in China and associations with 28 agronomic traits Chloroplast and whole-genome sequencing shed light on the evolutionary history and phenotypic diversification of peanuts Allelic variation of TaWD40-4B.1 contributes to drought tolerance by modulating catalase activity in wheat Genome-wide association study of leaf architecture in the maize nested association mapping population Genome-wide association study dissects the genetic architecture of oil biosynthesis in maize kernels Genome-wide association studies of 14 agronomic traits in rice landraces A map of rice genome variation reveals the origin of cultivated rice Resequencing 302 wild and cultivated accessions identifies genes related to domestication and improvement in soybean Genomic analyses in cotton identify signatures of selection and loci associated with fiber quality and yield traits domestication and diversification of Brassica juncea Resequencing of 429 chickpea accessions from 45 countries provides insights into genome diversity A chickpea genetic variation map based on the sequencing of 3,366 genomes Genome-wide association study of major agronomic traits related to domestication in peanut Genomic insights into the genetic signatures of selection and seed trait loci in cultivated peanut Comparison of Arachis monticola with diploid and cultivated tetraploid genomes reveals asymmetric subgenome evolution and improvement of peanut NextDenovo: an efficient error correction and accurate assembly tool for noisy long reads HiC-Pro: an optimized and flexible pipeline for Hi-C data processing Cytokinins: synthesis and biological activity of geometric and position isomers of Zeatin1 Conversion of N6-isopentenyladenine to zeatin by Actinidia tissues Evolution of cytokinin biosynthesis and degradation is associated with grain weight in hexaploid wheat Root-specific expression of chickpea cytokinin oxidase/dehydrogenase 6 leads to enhanced root growth drought tolerance and yield without compromising nodulation Conversion of N-(delta-isopentenyl) adenosine to adenosine by enzyme activity in tobacco tissue Cytokinins in the bryophyte Physcomitrella patens: analyses of activity and cytokinin oxidase/dehydrogenase overexpression reveal the role of extracellular cytokinins Evolutionary expansion and expression dynamics of cytokinin-catabolizing CKX gene family in the modern amphidiploid mustard (Brassica sp.) The AUXIN RESPONSE FACTOR 2 gene of Arabidopsis links auxin signalling Current status of structural variation studies in plants Major impacts of widespread structural variation on gene expression and crop improvement in tomato Asymmetric subgenome selection and cis-regulatory divergence during cotton domestication Genomic selection and genetic architecture of agronomic traits during modern rapeseed breeding The complex relationship between disease resistance and yield in crops fastp: an ultra-fast all-in-one FASTQ preprocessor Fast and accurate short read alignment with Burrows–Wheeler transform BCFtools/csq: haplotype-aware variant consequences A program for annotating and predicting the effects of single nucleotide polymorphisms SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3 Edgardo M. O. Vcf2phylip v2.0: convert a VCF matrix into several matrix formats for phylogenetic analysis. Zenodo https://doi.org/10.5281/zenodo.2540861 (2019) PHYLIP—phylogeny inference package (Version 3.2) PLINK: a tool set for whole-genome association and population-based linkage analyses Fast model-based estimation of ancestry in unrelated individuals Fast and accurate de novo genome assembly from long uncorrected reads NextPolish: a fast and efficient genome polishing tool for long-read assembly Chromosome-scale scaffolding of de novo genome assemblies based on chromatin interactions Benchmarking transposable element annotation methods for creation of a streamlined GenomeTools: a comprehensive software library for efficient processing of structured genome annotations IEEE/ACM Transactions on Computational Biology and Bioinformatics Vol LTR_FINDER: an efficient tool for the prediction of full-length LTR retrotransposons LTR_retriever: a highly accurate and sensitive program for identification of long terminal repeat retrotransposons Generic Repeat Finder: a high-sensitivity tool for genome-wide de novo repeat detection a new ensemble method for TIR transposable element annotation provides evidence for abundant new transposable elements in the maize genome HelitronScanner uncovers a large overlooked cache of Helitron transposons in many plant genomes TEsorter: an accurate and fast method to classify LTR-retrotransposons in plant genomes RepeatModeler2 for automated genomic discovery of transposable element families Using RepeatMasker to identify repetitive elements in genomic sequences Tandem repeats finder: a program to analyze DNA sequences Using intron position conservation for homology-based gene prediction Transcriptome assembly from long-read RNA-seq alignments with StringTie2 Comprehensive analysis of alternative splicing in rice and comparative analyses with Arabidopsis Using native and syntenically mapped cDNA alignments to improve de novo gene finding Automated eukaryotic gene structure annotation using EVidenceModeler and the program to assemble spliced alignments Draft genome sequence of bitter gourd (Momordica charantia) a vegetable and medicinal plant in tropical and subtropical regions BUSCO update: novel and streamlined workflows along with broader and deeper phylogenetic coverage for scoring of eukaryotic InterProScan 5: genome-scale protein function classification PANNZER2: a rapid functional annotation web server clusterProfiler: an R package for comparing biological themes among gene clusters OrthoFinder: phylogenetic orthology inference for comparative genomics Comparative genomics: the bacterial pan-genome Large-scale gene expression alterations introduced by structural variation drive morphotype diversification in Brassica oleracea ParaAT: a parallel tool for constructing multiple protein-coding DNA alignments Muscle5: high-accuracy alignment ensembles enable unbiased assessments of sequence homology and phylogeny KaKs_Calculator 3.0: calculating selective pressure on coding and non-coding sequences Using MODELTEST and PAUP* to select a model of nucleotide substitution D-GENIES: dot plot large genomes in an interactive New strategies to improve minimap2 alignment accuracy Adaptive seeds tame genomic sequence comparison SVIM-asm: structural variant detection from haploid and diploid genome assemblies Long-read-based human genomic structural variation detection with cuteSV Truvari: refined structural variant comparison preserves allelic diversity Transient structural variations have strong effects on quantitative traits and reproductive isolation in fission yeast Pangenome graph construction from genome alignments with Minigraph-Cactus Variation graph toolkit improves read mapping by representing genetic variation in the reference Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype The Sequence Alignment/Map format and SAMtools BEDTools: a flexible suite of utilities for comparing genomic features Population differentiation as a test for selective sweeps A comprehensive benchmark of graph-based genetic variant genotyping algorithms on plant genomes for creating an accurate ensemble pipeline GraphTyper2 enables population-scale genotyping of structural variation using pangenome graphs GraphAligner: rapid and versatile sequence-to-graph alignment Pangenome-based genome inference allows efficient and accurate genotyping across a wide spectrum of variant classes Variance component model to account for sample structure in genome-wide association studies Interactive Tree of Life (iTOL) v5: an online tool for phylogenetic tree display and annotation Bandage: interactive visualization of de novo genome assemblies RCircos: an R package for Circos 2D track plots Samplot: a platform for structural variant visual validation and automated filtering JBrowse 2: a modular genome browser with views of synteny and structural variation LDBlockShow: a fast and convenient tool for visualizing linkage disequilibrium and haplotype blocks based on variant call format files MEGA5: molecular evolutionary genetics analysis using maximum likelihood FastTree 2—approximately maximum-likelihood trees for large alignments Highly accurate protein structure prediction with AlphaFold A new mathematical model for relative quantification in real-time RT–PCR The circadian-controlled PIF8-BBX28 module regulates petal senescence in rose flowers by governing mitochondrial ROS homeostasis at night Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana Xue, H. PeanutPAN: pan-genome for peanut genomics study (1.0.0). Zenodo https://doi.org/10.5281/zenodo.15003999 (2025) Download references The computations in this paper were run on the π 2.0 cluster supported by the Center for High Performance Computing at Shanghai Jiao Tong University This work was supported by grants from the Key Program of National Natural Science Foundation of China (NSFC)-Henan United Fund (grant number U22A20475) Key Scientific and Technological Project of Henan Province (grant numbers 221111110500 National Natural Science Foundation of China (grant number 32170643) Natural Science Foundation of Shanghai (grant numbers 20ZR1428200 Shanghai Key Program of Computational Biology (grant number 23JS1400800) and National key R&D program (grant number 2023YFF1001600) acknowledges the start-up grant from the Food Futures Institute of Murdoch University decision to publish or preparation of the manuscript These authors contributed equally: Kunkun Zhao and Kai Zhao prepared the samples and reagents All authors read and approved the final paper The authors declare no competing interests Nature Genetics thanks the anonymous reviewers for their contribution to the peer review of this work Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Download citation DOI: https://doi.org/10.1038/s41588-025-02170-w Anyone you share the following link with will be able to read this content: a shareable link is not currently available for this article Sign up for the Nature Briefing newsletter — what matters in science Adults with peanut allergies may be able to reduce their risk by slowly acclimatizing to peanut protein Scientists realized relatively recently that parents could reduce a child’s chance of developing a peanut allergy by exposing them to small amounts during infancy, a discovery that forced a U-turn in parenting advice in much of the world But it wasn’t known whether the same was true for adults, whose immune systems are more developed. Scientists gave 21 subjects the equivalent of 2.5% of a peanut daily before building the doses up but 14 ended up able to eat five peanuts safely One man told the BBC his allergy had almost killed him, but he now eats peanuts every day Sign up for Semafor .css-w8sqnb{text-transform:capitalize;}flagship Trophy Nut Company is recalling cans of its Honey Roasted Peanuts due to the potential inclusion of cashews Newsweek reached out to Trophy via email Wednesday night for comment Numerous recalls have been initiated this year due to potentially damaged products undeclared food allergens or the potential for bacteria Millions of Americans experience food sensitivities or food allergies every year. According to the U.S. Food and Drug Administration (FDA) the nine "major" food allergens in the United States are eggs cashews fall under the tree nuts category of food allergens so the sensitivities and reactions for those allergic vary between the two In an alert posted by the FDA on Wednesday the recalled peanuts were distributed in Heinen's Grocery Stores in Illinois and Ohio from October 24 The recalled products have a UPC number of 20601401877 and they are packaged in an 8.25-ounce composite can with a best if used by date of October 1 The FDA alert notes that 143 cases of the peanuts are being recalled According to the agency, there has been one allergic reaction reported as of Wednesday. It also posted a picture of the recalled product in its alert. in part: "The recall was initiated after receiving a consumer complaint that product labeled as Honey Roasted Peanuts contained cashews Subsequent investigation indicates the problem was caused by a temporary breakdown in the company's production and packaging processes." The FDA, in part, on its website in March: "Food allergic reactions vary in severity from mild symptoms involving hives and lip swelling to severe that may involve fatal respiratory problems and shock While promising prevention and therapeutic strategies are being developed Early recognition and learning how to manage food allergies are important measures to prevent serious health consequences "To protect those with food allergies and other food hypersensitivities the FDA enforces regulations requiring companies to list ingredients on packaged foods and beverages For certain foods or substances that cause allergies or other hypersensitivity reactions there are more specific labeling requirements." Customers who have purchased the recalled nuts may return them to a Heinen's Grocery Store for a full refund People with additional questions may also contact the company's customer service at 1-800-729-6887 from 8 a.m. to 4 p.m. ET weekdays or email the company at custserv@trophynut.com Newsweek is committed to journalism that's factual and fair Hold us accountable and submit your rating of this article on the meter. sustainability and economics are among the topics on the agenda for the 45th South Carolina Peanut Growers Meeting The morning session includes a welcome from Richard Rentz chairman of the South Carolina Peanut Board South Carolina’s commissioner of agriculture Josey Peele of AMADAS Industries will discuss technological advances in peanut harvesting and Eric Streepy of the Kelley Manufacturing Company (KMC) will present on combine setup and maintenance Kendall Kirk Clemson Extension precision agriculture engineer will provide an update on using precision agriculture in peanut research sustainability director for the American Peanut Council The morning session concludes with a presentation by Clay Pirkle director of operations for the Georgia Federal-State Inspection Service on using improved probe technology for the buying point Peanut yield contest awards will be announced during lunch followed by prize drawings before the afternoon session begins The KMC Grand Prize is a $5,000 voucher to be used towards a piece of equipment or parts growers must visit the Kelley Manufacturing Company booth for entry and be certified as a peanut grower with a Farm Service Agency farm number Grand Prize from AMADAS is the use of a new 4-row or 6-row AMADAS Peanut Digger/Inverter for the 2025 harvest season or $10,000 towards the purchase of a new AMADAS Self-Propelled Peanut Combine or $5,000 towards the purchase of a new AMADAS 4-row or 6-row Pull-Type Peanut Combine growers must be 2024 commercial peanut growers who intend to plant peanuts in 2025 The afternoon program includes a cost and returns outlook from Nathan Smith Other speakers include Riley Godwin of the South Carolina Department of Natural Resources Region 3 Law Enforcement Division who will address the proper use of depredation permits for wildlife management Michael Marshall, Clemson Extension agronomic weed specialist, will provide a weed control update. Dan Anco will discuss twin row and growth regulator effects on maturity and pod distribution The meeting is expected to conclude at approximately 3 p.m Continuing education and pesticide credits have been applied for. For more information, contact Dan Anco at 630-207-4926 or danco@clemson.edu.  Or email us at news@clemson.edu Clemson News is the go-to source for stories and news about the innovations research and accomplishments of the Clemson Family Share on FacebookShare on X (formerly Twitter)Share on PinterestShare on LinkedInDOTHAN (WTVY) - The city of Dothan is known as the ‘Peanut Capital of the World’ because the majority of peanuts in the United States are grown within a 100-mile radius of Dothan Until the 1920s when the boll weevil got a hold of the fields and left farmers in the South with destroyed fields and left farmers with little to no money George Washington Carver came into the picture Carver who was a professor of agriculture at Tuskegee University discovered hundreds of uses for peanuts relating to cooking Carver didn’t stop there as he also introduced field rotation to farmers in the area meaning that fields could be exhausted by continual planting the soil on farm lands matched well for growing shallow peanut plants which led to revitalized farming around Dothan launched the “Peanuts Around Town” project designed to reinvigorate the downtown Dothan area and increase tourism crafted by local artists and Replica Plastics to showcase residents and businesses You can find these sculptures placed in front of shops One of the most famous peanut sculptures everyone probably knows about is the one at located the Driver’s License Office Parents usually take their child’s picture beside the peanut once they get their license the city of Dothan has a total of 91 sculptures in town and four in surrounding areas The boll weevil caused some damage but made up for it as the agricultural economy flourished in the end salted green peanuts boiled in brine were sold during the summer months throughout Dothan “Peanut Capital of the World.” you can find this marker located on the east side of Adams Hall In support of Dr.Caver’s extensive research you can find him honored on murals and in museums in Dothan The Dothan Visitor’s Information Center located at 3311 Ross Clark Circle NW offers a map that outlines the locations of each peanut sculpture for anyone interested in a self-guided tour 2024-PeanutMap by Cassidy Lee on Scribd Subscribe to our News 4 newsletter and receive the latest local news and weather straight to your email every morning. Get instant notifications on top stories from News 4 by downloading our mobile apps 2024-PeanutMap by Cassidy Lee on Scribd Reese's has introduced a Peanut Butter White Bar in the U.K. combining its signature peanut butter filling with a white chocolate flavored coating featuring the ridges of Reese's Peanut Butter Cups The product aims to cater to the growing popularity of white chocolate which reportedly saw a 32.9% increase in sales in the U.K The recommended retail price for the bar is £1.75 The Reese's Peanut Butter White Bar is available at ASDA and SPAR stores across the U.K. "We are excited to introduce the Reese's Peanut Butter White Bar to British consumers building on the success of the original Reese's Peanut Butter Bar," Jackson Hitchon Africa and world travel retail at The Hershey Company Get the latest news and resources from Vending Times Sign up to receive GPB Event announcements via Email LISTEN: GPB's Orlando Montoya speaks to Mark Moore a Georgia nonprofit organization that manufactures peanut products for malnourished children.  This comes after a federal judge temporarily blocked a plan for employee “buyouts.” It's part of the Trump administration's plans to strip down the agency along with unprecedented efforts to cut the federal budget This week, USAID’s staff was cut from more than 8,000 direct hires and contractors to fewer than 300 employees, the Associated Press reported with President Trump writing on social media Friday This move came after Trump associate and Department of Government Efficiency head Elon Musk called USAID a “criminal organization” in a Feb. 2 post on his X platform The dismantling of USAID could have negative impacts on local economies in South Georgia where peanut products are created to send overseas to severely malnourished children nonprofit that makes a children’s survival mixture from milk and peanuts known as an RUTF — or ready-to-use therapeutic food MANA manufactures enough packets of the vitamin-rich paste to feed approximately 2 million children per year through programs by USAID But MANA received a stop work order from USAID about a week ago Confusion set in nationwide as Musk’s “DOGE” group began shutting down websites and agency functions. Secretary of State Marco Rubio said there would be waivers for emergency food aid as part of the Food for Peace Title II Act under the Farm Bill implemented by USAID’s Bureau for Humanitarian Assistance Moore said his $80 million budget for MANA this year includes a variety of contracts for the RTUF but is largely subsidized by USAID A Feed the Future Innovation Lab for Peanut Research through the University of Georgia which aimed to help farmers in developing countries grow and profit from healthy peanut crops by learning from producers in Georgia “We were nervous there for a week trying to decide Are they going to honor contracts?' — things like that,” Moore said we got an email from our contracting officer saying 'You can start working on these projects.'” Even if Moore and his 130 employees who make and pack the MANA product for shipping abroad from the Port of Savannah are allowed to continue producing for now he is concerned about the logistics facing an understaffed USAID supply chain “[There are] just too many moving parts at USAID for such a drastic cutback to not have some effect “I can't say specifically what it will be." Fitzgerald has a population of around 9,000 people. Moore reckons MANA is one of the top employers in the town the plot across the street rotates between cotton and peanuts According to the USDA, Georgia produces more peanuts than all other states combined. The Georgia Peanut Commission's 2023 report noted Georgia's 4000 peanut farmers harvested 778,000 acres of peanuts in 77 counties, yielding a $2.2 billion industry. The crop's dominance is one of the reasons Gov. Brian Kemp celebrated MANA’s expansion in May 2022. "It’s great to see the amazing work done by hardworking Georgians in Ben Hill County," Kemp said in the statement. "We are excited to watch MANA Nutrition serve communities in need worldwide with products from our state's No. 1 agriculture industry. We have been laser-focused on creating impactful opportunities across the state, and jobs like these will be good for the local community for years to come.” Jason Dunn, Director of the Fitzgerald-Ben Hill Development Authority, also praised MANA’s and local farmers’ “combination of Georgia Grown peanuts and the state-of-the-art production … expanding the reach of Georgia’s ag legacy." Last July, MANA broke ground on the refurbishment of a 320,000 square foot facility in Pooler, Ga., a few miles from the Port of Savannah, calling it “one of the largest dedicated humanitarian warehouses in the United States of America.” Georgia Ports President and CEO Griff Lynch said he was "honored to handle [MANA's] vital product line through our port.” Samantha Power, the former USAID Administrator with strong Georgia ties who served until Jan. 20, 2025, when Jason Gray was appointed to the role by Trump, visited the Fitzgerald location in May 2024. Power attended Atlanta’s Lakeside High School as a child and was later lauded in her role as U.S. Ambassador to the United Nations under President Obama as “a powerful representative of the United States” by the late Republican senator from Georgia, Johnny Isakson. In a Feb. 5 interview on MSNBC, Power said the current administration’s targeting of USAID relied on the public not knowing what U.S. impacts it had. “The calculated bet here was that this was for foreigners,” she said of perceptions about the organization she led for four years. “The people who are trying to destroy the agency aren’t people who know anything about what USAID does, they don’t know we deliver magical peanut paste made in rural Georgia that Georgia farmers care passionately about being part of … they take pride in bringing those kids, basically, back to life.” As for Moore, he said he hopes Americans understand what a small fraction of taxpayer dollars actually go to fund USAID as part of the overall U.S. budget. “Our giving to USAID as a government entity is [equivalent to] $100 out of $50,000; it's two-tenths of 1%,” he explained as an analogy. “So is it acceptable to waste any of it? No. Should we misspend it?  No. Should we look at it and examine it? Yes. But if you eliminate it, is it the thing that's going to change your financial situation? And what is the impact, then, of eliminating that $100 spend in your $50,000 budget? And it's massive.” Moore said that the future of USAID may be blurry but the livelihood of his nonprofit organization's employees and the need for MANA's lifesaving product around the world are clear.  "We're not discouraged yet," he said. "We're going to keep going, and finding a way forward is too important to just sit around and sort of indulge in feeling sorry for ourselves. We're going to get it done." Orlando Montoya is newscaster producer for Georgia Public Broadcasting. Kristi York Wooten (she/her) is a digital editor and journalist based in Atlanta. She works with the GPB radio and digital news teams as an editor, writes and produces features for digital and radio and leads editorial and production for the GPB News Weekend newsletter. Her work appears in The New York Times, The Economist, The Atlantic, Newsweek, Rolling Stone and others. GPB is committed to bringing you comprehensive news coverage from Georgia, across the country and around the world.  Your support makes this possible.  Please consider making a gift today to support this vital public service. Notifications can be managed in browser preferences. A new trial gives "hope" to thousands of people who suffer from nut allergies I would like to be emailed about offers, events and updates from The Independent. Read our Privacy notice A 44-year-old man with a life-threatening peanut allergy can now eat a handful of peanuts every morning as part of his daily routine who has experienced multiple hospitalisations due to accidental peanut exposure Lassiter's severe allergy previously dictated his life requiring constant vigilance to avoid even trace amounts of peanuts This new development offers a glimpse into a future where adults with peanut allergies might be able to live without the constant fear of accidental exposure Experts highlight that previous desensitisation studies primarily focused on children, leaving adults with limited treatment options suggests that similar treatments could be effective for adults the study's success provides hope for thousands of adults living with the daily challenges of severe peanut allergies Health officials said the trial gives "hope" to thousands of people. The peanut desensitisation, also known as oral immunotherapy, works by introducing micro amounts of peanuts and gradually increasing the dosage to build up immunity. Mr Lassiter, an executive coach from Beckenham in Greater London, was diagnosed with a peanut allergy as a child. He told the PA news agency that he “managed” his condition but always felt nervous eating out. “I had a really severe episode on our once-in-a-lifetime holiday to Chile with my wife in 2018 that changed everything,” he said. He said that the episode occurred when they were on holiday “1,000 miles from anywhere” when he was given food with peanuts in. Mr Lassiter took his auto-injector pen, and his inhaler to ease his breathing, and was taken to hospital by ambulance. He had to stay in a high dependency unit overnight where he needed adrenaline and oxygen. “It was a real shock, because obviously we’re a long way away from home,” he told PA. “I recall saying to my wife: ‘I can’t keep dealing with this, it’s just so terrifying’.” On another occasion, during a meal out in Soho in London, Mr Lassiter said that he accidentally ate peanuts after they were hidden under some ice cream. “Within a few seconds, I knew I was in trouble. “By the time I was in St Thomas’s it was pretty bad – I remember I’d swollen up to a huge size relative to my normal size and asking the nurse if I was going to make it.” Speaking about the new study, he said: “I got to the point where I was having a total of four peanuts a day, which I still take to this day. “This morning I had my four peanuts after I ate my breakfast, as if it was some sort of a teaspoon of medicine.” He added: “It’s been life-changing for me – it’s increased my confidence immeasurably. “It’s had a huge effect on my life. I feel much calmer, much happier and really excited about the ability to do all of these things in the future.” Researchers from King’s College London and Guy’s and St Thomas’ NHS Foundation Trust stressed that this type of treatment should only be initiated under very close supervision. Their new study, published in the journal Allergy, saw 18 adults with a typical peanut allergy gradually desensitised to peanuts. After their allergy was confirmed by teams in hospital, patients were given small amounts of peanut flour to eat at home, starting with the equivalent of 0.5% to 1% of a whole peanut. Their dosage increased gradually and once they could tolerate 50-100mg of peanut protein they were switched to eating whole peanuts, peanut butter or peanut products. By the end of the study, which was funded by the National Institute for Health and Care Research, two thirds (67%) were able to eat the equivalent of five peanuts without reacting. Chief investigator Stephen Till, professor of allergy at King’s College London and consultant allergist at Guy’s and St Thomas’, told the PA news agency: “The problem is that once I see (adult) patients in my clinic, there’s been nothing that we’ve been able to do to them – we can’t offer them desensitisation because the data is all from young children – in medicine you can’t give treatment to children or to adults based on a clinical trial that’s been performed in the other group. “So we have got this sort of, and continue to have this sort of big unmet need of adults with peanut allergy.” He added: “We were really pleased because we got the evidence that we hoped we would get – we saw results that were broadly in line with with what been obtained from studies in young children. “Our phase two study suggests that this treatment is is potentially effective in adults.” But he said larger studies were needed to confirm findings and stressed that food immunotherapy “definitely must be done under very close clinical supervision”. Commenting on the study, public health minister Ashley Dalton said: “This ground-breaking research offers hope to thousands living with peanut allergies. “For too long, people have navigated daily life in fear of accidental exposure that could be life-threatening.” Professor Lucy Chappell, chief scientific adviser at the Department of Health and Social Care and chief executive of the NIHR said: “These results mark an important milestone in allergy treatment and offers new hope to adults living with peanut allergies. “For adults who have long lived with the daily burden and fear of accidental exposure they may have a pathway toward greater safety and an improved quality of life.” Commenting on the study, Adam Fox, chair of the National Allergy Study Group, and professor of paediatric allergy at King’s College London, said: “Conventional wisdom has been that oral immunotherapy for food is really just for children and there is clear evidence that the younger it is started, the safer and better the outcome. “However, that doesn’t mean that the benefits would not still be worthwhile for adults, and this study shows that for many, oral immunotherapy for peanut at least, can still make a real difference. “This is only a small study and we hope to see larger studies to follow, but it’s an important proof of principle that this may well be a treatment for adults too. “However, this treatment requires careful medical supervision and should never be attempted without this.” Join thought-provoking conversations, follow other Independent readers and see their replies In celebration of National Peanut Day on Sept the makers of the PLANTERS® brand are thrilled to announce the launch of PLANTERS® Special Reserve peanuts These limited-edition peanuts are specially grown catering to the discerning palate of true peanut connoisseurs Harvested on less than 150 acres under the sun-soaked fields of Virginia PLANTERS® Special Reserve peanuts are cultivated to be considerably larger than the standard peanut making them the epitome of premium snacking “We are excited to offer this exclusive product to our loyal fans and to honor the long-standing legacy of MR “PLANTERS® Special Reserve peanuts embody the pinnacle of quality and taste and we are delighted to celebrate National Peanut Day with such a premium offering.” Peanut aficionados and MR. 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Available exclusively at mrpeanutspecialreserve.com for $19.06 — a nod to the year the PLANTERS® brand was founded — these peanuts are destined to become a treasured keepsake To allow more peanut fans to take advantage of the PLANTERS® Special Reserve peanuts a limited quantity of canisters will also be available at Walmart.com and Amazon.com For more information about PLANTERS® products PEANUT® and the limited-edition PLANTERS® Special Reserve collection the Planters® brand has been the ultimate snacking solution for consumers for over a century with a vast portfolio of peanuts No matter what you’re craving — salted mixed nuts — Planters® products have you covered which has been owned by Hormel Foods Corporation (NYSE: HRL) since 2021 who is currently touring the salty streets of America in his world-famous NUTmobile Fans of the Planters® brand can request the world’s largest peanut on wheels by submitting a request at plantersnutmobile.com/request For more information on all Planters® products