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Elizabeth Michelle “Beth” Heesch
1990 in Omaha to Donald and Michelle (Moser) Dooley
Beth grew up in Yutan and graduated from Yutan High School in 2008
She then received her associate’s degree from Metropolitan Community College
She married Nicholas “Nick” Heesch on August 29
Beth participated in Renaissance Fairs in the Omaha area
and she enjoyed playing Dungeons & Dragons with friends
Donald (Michelle Moser) Dooley of Yutan; siblings
NY and Michaela Dooley of Yutan; grandparents
Lorina Patterson of Louisiana; niece and nephew
2025 at Heafey-Hoffman-Dworak-Cutler Mortuary 7805 W
Visitation will be 4-7 PM Tuesday with a Rosary starting at 7 PM at Heafey’s in Omaha
Visitation continues on Wednesday 1 hour prior to the service also at Heafey’s
Interment will be at Resurrection Cemetery in Omaha
Online condolences may be left at www.mosermemorialchapels.com
Heafey-Hoffmann-Dworak-Cutler, West Center Chapel, 7805 West Center Road, Omaha, Ne 68124. (402)-391-3900. www.heafeyheafey.com
Our prayers for your healing ❤️🩹 are on our lips
We pray that you will remember forever the good days and fun times
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People often said Craig Faye Heesch “restored their faith in humanity.”
Craig passed away peacefully in Saint George
Craig’s arrival into the world was as remarkable as the life he would live
After celebrating the 4th of July at a dance
where Craig was born prematurely at just 3 ½ pounds
beginning a journey that would defy the odds
He learned to sing while standing in his crib
blending his voice with Frank Sinatra’s instead of taking a nap
with his five siblings and several cousins
living in log cabins and helping their parents run the Whispering Pines Resort
Craig was educated in a one-room schoolhouse
where a neighbor—who initially reprimanded Craig and his brother for breaking bottles into the creek—soon became a close friend and introduced Craig to The Church of Jesus Christ of Latter-day Saints
He was baptized and remained steadfast in his faith every day of his life
It was in this ward where he first met Varna Howell
Craig worked installing the telephone system in Medford
Air Force and later the Air National Guard
and with encouragement from the legendary Mel Tormé
Craig pursued singing as a strong interest when he wasn’t providing for his then wife
later divorced and then continued his business endeavors
Craig's strong work ethic led him to create successful businesses
where he survived a plane crash and subsequent jungle imprisonment
His plight even caught the attention of President Ronald Reagan
Craig returned home to the United States and went on to invent a bellow-type screw that was patented and used in the aerospace industry
Craig's brother called him to say that Varna was single and suggested he contact her
Craig's smooth voice continued to captivate audiences
His singing career included performances at prestigious venues such as the Lincoln Center in New York
and he performed as the guest artist with the famed 72-piece Seoul Pops Orchestra in Korea
Craig’s album From Out of the Wings was produced by Jim Pike
and received many Grammy Award nominations
Renowned jazz authority Johnny Adams also praised Craig’s vocal successes
“Not since Frank Sinatra or Buddy Greco have I been so impressed with a vocalist.”
Craig's keen mind and exemplary ambition led him to employment as a policeman for the Culver City Police Department
and a certified Master Golf Instructor who taught on the LPGA Tour and at Dixie College
Craig's contributions to both music and business were remarkable
but those who knew him best remember him for his unwavering faith
He and Varna served for ten years in the San Diego temple and also served a mission for The Church of Jesus Christ of Latter-day Saints on Temple Square from 2016 to 2017
where they were adored by the 200 young women who had the privilege of knowing Craig
His impact on their lives was immeasurable
One of the many things those close to Craig will remember is his passion for culinary creations
With this came a unique and often perfectionist approach to his cooking
The reward for his efforts was the joy of sharing his creations with family and friends
Craig was a man whose life was first and forever grounded in faith
and unwavering belief in the good in others will live on in the hearts of all who knew him
After years of struggling with declining health
“I’m ready to go home.” Shortly thereafter
Varna; son Craig Allen (Angela) Heesch; daughter Colleen Flint; grandchildren Ashley (Shane) Harder and Vincent Craig Heesch; and darling great-granddaughters Sienna
and Kira; stepchildren Cheri (David) Meiners
and Andrea (Dylan) Wolfe; 14 great step-grandchildren; and sister Diane Smith
Preceded in death by Robert Erik Jorgensen
A memorial service for Craig will be held on Tuesday
at The Church of Jesus Christ of Latter-day Saints
A visitation at the same address will begin at 9:00 a.m
Join the Zoom meeting after 9:45 @ https://zoom.us/j/91707904520 Meeting ID: 917 0790 4520
feel free to donate in his honor at: https://www.churchofjesuschrist.org/comeuntochrist/light-the-world/giving-machines
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which officials say is likely to dissolve in two years without additional funding
is putting its third operating referendum in less than a year on the Feb
During a special meeting earlier this month
the Mauston School Board unanimously voted to put a four-year
which will include a primary election for state superintendent of public instruction
That same referendum failed by 69 votes on Nov
the district began the process of dissolving by the 2026-27 school year
saying it would no long be able to fund operations
Mauston School District Superintendent Joel Heesch said area stakeholders advised him and the board to retry the $1.75 million per year referendum after the narrow rejection on Nov
I see a future with this district and I could see the future for years,” Heesch said during the meeting Dec
That’s why the consideration of dissolution.”
a $9 million referendum over four years failed by a much larger margin
Heesch said that the district must pass the Feb
“We are not in a position where we can swing and miss,” Heesch said
referring to another potential referendum rejection
the owner of a $200,000 home in the district would pay roughly $1,442 in school property taxes in 2025-26
That is a $130 projected decrease from the amount paid for the same home in 2023-24
as the district has paid off capital referendum debt from its technical education wing and Grayside Elementary School projects earlier this decade
Heesch has said the district would likely adopt a second resolution in July ordering dissolution
The district’s emergency fund balance of just over $2 million would likely be exhausted for operating expenses over the next two school years without referendum funding
School Board Vice President Mike Zilisch and member Betty Kryka expressed a desire to go for a four-year
$9 million measure again but said a $7 million referendum would have a better chance of approval by district voters
“The $1.75 (million) will get us by for at least four years,” Kryka said
“Are we then going back to the community again?”
Zilisch said that unless the state funding formula for public education changes
the district would likely need to propose another referendum after the four-year measure expires
$7 million referendum would still result in some program cuts and positions remaining unfilled
but it would allow the district to retain and restore many of its current programs and staff
Mauston School District residents can contact district Superintendent Joel Heesch at jheesch@maustonschools.org or at (608) 847-5451
New restaurants and businesses are opening in La Crosse area
A 47-year-old Blair man faces criminal charges after he was arrested in Holmen during a child sex sting
A 34-year-old La Crosse woman faces multiple criminal charges after an April 10 traffic stop in La Crosse
A tornado touched down in Eau Claire County Monday according to the National Weather Service
A traffic stop of a wrong-way driver in La Crosse on April 3 resulted in drunken driving charges
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A Juneau County school board is considering dissolving its district after voters failed a referendum needed to continue operations
The School District of Mauston’s Board of Education approved a resolution to consider dissolution at their meeting on Monday
Superintendent Joel Heesch said there is no immediate action being taken to dissolve
But the resolution allows the board to consider the district’s next steps
“It’s just a matter of us being able to lay out this timeline,” Heesch said
“We have two more years with the current status that we have financially
Mauston leaders had tried to address the district’s projected budget shortfall through an operational referendum
The first proposal in April would have given the district $2.25 million in each of the next four years
But Heesch said voters overwhelmingly rejected the referendum
forcing the school board to reconsider their ask
The board put another operating referendum on the November ballot for $1.75 million in each of the next four years
which Heesch said would have led to some budget cuts by the district
Voters failed the referendum again, this time by 69 votes — or less than 2 percentage points. It was one of 30 school referendums that voters failed statewide this month, according to an analysis by the Wisconsin Policy Forum.
“What we continue to tell people is that $1.75 (million) gave us a future, something that we could see years down the road,” Heesch said. “Zero did not. We just could not see a future with zero.”
Heesch said the board plans to put forward another operational referendum on either the February or April ballot. But the district, which has 250 employees and 1,400 students, is also preparing for the possibility that the measure will not be successful.
The school board approved a myriad of budget cuts for the 2025-26 school year that include closing an elementary school and cutting all sports, clubs and field trips.
Mike Zilisch, vice president of Mauston’s school board, said he worries that these budget cuts will push students and families to start leaving the district, which would further hurt their budget because of the state’s enrollment-based funding formula.
“We’re going to lose that (state) revenue from those kids,” Zilisch said. “It really is kind of a death spiral, if you will. As more of these things come to fruition, the more and more tough decisions we’re really going to have to make.”
He said the district already chose not to fill more than 20 vacant staff positions for the current school year, which he said has hurt student learning and put more stress on remaining staff.
Both Zilisch and Heesch pointed to the state’s school funding formula as part of why the district is facing financial challenges.
“It’s so enrollment driven, which is a challenge in rural areas,” Heesch said. “You’re seeing declining enrollments, your revenues are either flat or decreasing based on those enrollments, while your expenditures, especially through an inflationary period, have increased dramatically.”
Based on public comment given at Monday’s meeting, Zilisch said he also believes some community members voted down the referendum this month because of misinformation about whether the district was really facing a budget deficit.
“We need to push out the message that we really do need this money,” he said. “We’re not asking for $1.75 (million) because we want to. We’re asking for $1.75 (million) because we need it. We need it for our kids. We need it for the community.”
He said the board will hold a special meeting in early December to decide how to approach their next operating referendum.
Wisconsin Public Radio, © Copyright 2025, Board of Regents of the University of Wisconsin System and Wisconsin Educational Communications Board.
Volume 12 - 2024 | https://doi.org/10.3389/fchem.2024.1386055
A promising pollution control technology is cold plasma driven chemical processing
The plasma is a pulsed electric gas discharge inside a near atmospheric-pressure-temperature reactor
The system is energized by a continuous stream of very short high-voltage pulses
The exhaust gas to be treated flows through the reactor
The methods applied involve the development of robust cold plasma systems
industrial applications and measuring technologies
Tests of the systems were performed at many industrial sites and involved control of airborne VOC (volatile organic compound) and odor
chemical and odor measuring data were collected with state-of-the-art methods
To explain the test data an approximate solution of global reaction kinetics of pulsed plasma chemistry was developed
The latter shows that the amount of removal
This variable is electric plasma power divided by gas flow divided by input concentration
In the results sections we show that in some cases up to 99% of volatile pollution can be removed at an acceptable energy requirement
In the final sections we look into future efficiency enhancements by implementation of (sub)nanosecond pulsed plasma and solid state high-voltage technology and by integration with catalyst technology
The plasma is a pulsed electric gas discharge
It appears as a cloud of electric mini sparks contained in a reactor at atmospheric pressure
This cloud is being energized by a stream of very short high-voltage pulses
The air to be treated flows through the reactor
The processes run continuously over a long period of time (hours to days or months)
the high voltage is not continuous but pulsed
The pulses are very short (5 ns - 5 microsecond) and are repeated at high rate (100 Hz–10 kHz)
Pulsing the plasma over a long time means that chemical processing behavior is pulsed as well as quasi continuous; actually
the process is a near infinite row of short duration
To be able to realize this continuous operation
systems with robust high-voltage power source and reactor have been developed
They can operate over long periods of time (weeks to months)
Important challenges within this technology area are raising the levels of performance in the areas: removal efficiency
overall reliability and resilience to dust and condensing water
The main purpose of this paper is to present the principle of cold plasma processing
two industrial plasma processing systems and results of case studies performed with these systems
a deeper look at plasma processing kinetics
and finally a look into the future of plasma processing
The applied pulsed plasma technology relies basically on the combination of a pulsed power source and a plasma reactor at atmospheric conditions
The pulsed power source delivers a flow of electrical energy pulses to the reactor
5–100 ns wide and has a power level that peaks at levels up to hundreds of Mega Watt
These pulses are repeated at a rate of 10–5,000 pulses per second
The pulsed power source takes its energy from the grid and delivers it to the plasma in the reactor at an efficiency of up to around 80%. The plasma delivers this energy to the electrons with an efficiency between ca. 1%–50% (van Heesch et al., 2008)
The electrons initiate the chemical process
This process is a chemical conversion from reactants into products
This conversion can be expressed as the concentration of reactants converted
divided by the concentration of reactants on input
The conversion will be compared with the electrical energy needed to perform this conversion
This electrical energy is expressed as an energy density
This energy density is defined as electrical energy divided by treated volume
This is the same as the electrical power into the reactor divided by volumetric gas flow into the reactor
It is the crucial parameter for pulsed plasma processing
Species particle concentration for reactants and products are the other important parameters
Figure 1. (A) Layout of the nanosecond cold plasma system (Beckers, 2015). (B) Basic layout of the circuit called “Ch charger” in panel A is given by the left part of the circuit in panel (B). The functionality is described in Beckers (2015)
Figure 2. (A) Typical voltage and current traces for the plasma reactor of the nanosecond system. (B) The container with the nanosecond system. More information in Beckers (2015)
(A) Layout of the microsecond cold plasma system
(B,C) Photos of the container housing the microsecond system and of the ozone reactor
Figure 4. (A) Electric layout (simplified) of the microsecond cold plasma system. More information in Li et al. (2018)
(B) Typical voltage traces at the terminals of the DBD plasma reactor of the microsecond system
We obtained this result by applying circuit simulation software (LTspice) for fitting the calculated response of circuit to the measured behavior
The 5 kW and the 20 kW device were mounted in 20-ft freight containers for housing
They are equipped with fully automated control
Both systems can be remotely controlled via a protected internet connection
The microsecond plasma machine was equipped with a post-processing device
added to the output of the plasma machine serves as plug flow reactor to convert residual ozone
Layout and pictures of the device are shown in Figures 3A–C
we made a comparison with an industrial RONS injector device
This injector technology is commercially available from several manufacturers
It is housed in a reactor chamber separate from the exhaust process flow
A very clean air flow is fed into the device and the output flow is injected into the exhaust flow
Chemically active species from plasmas (radicals)
have short lifetimes (100 microsecond or less)
The relatively long transit time from plasma production chamber of the injector device to stack will reduce the effectiveness of the active species
Ozone will easily survive the transit time but for O and OH radicals it will be difficult
divided by the reactor volume and N is the number of pulses applied during reactor transit time
The value of a cannot be well established but can be assumed to be very small
1. Global chemical kinetics developed in (van Paasen et al., 1997; Yan et al., 2001)
Multiple pulsed plasma volumes in which reactive species are generated by a high-voltage pulse
The sum of transient plasma volumes created during the reactor transit should be larger than the reactor volume (a.N > 1)
Reactive species induced oxidative degradation of target compounds
Remixing of the plasma volumes into the reactor after each pulse
detailed knowledge of rate constants would be needed
we performed a least-squares fit on the data to obtain values for γ and k
Equation 1 is implicit in the unknown X. It can be found that the solution involves the application of the Lambert function W(z). This function is defined as the inverse of f(z), where f(z) = z.exp(z). We only use the positive part of the principal branch of W, denoted by (W0), and apply real arguments. We used Mathematica from Wolfram (Weisstein, 2002) to obtain the explicit solution of Eq. 1:
Figure 5 shows the behavior of the value of the conversion X
Three data sets have been plotted: the measured data
the model according to the Lambert function (Model 1) and a simplified expression according to an exponential function of k.E/C0 (Model 2):
Figure 5. 2D graph of conversion as a function of the parameter E/C0. The triangles are the 82 measured data points collected during 3 days of on-site testing. The squares are the values according to the solution Eq. 2 (Lambert function) of Eq. 1. The smooth curved line is according to the approximation in Eq. 4
Equation 4 was already given in 1986 by Masuda as based on the best fit to his experimental data (Masuda and Nakao, 1986)
The parameters k and γ in Eqs 2, 3 were fitted (least squares, linear) to our measured data to obtain γ = 4.813 ppm and k = 2.053 ppm m3/Wh. Figure 6 shows the 3D plot of the solution of Eq. 1, fitted to the measuring data. Figure 7 is the 2D projection of the 3D surface of Figure 6
Figure 6. 3D surface as the implicit solution of Eq. 1
The dashed black lines are lines of constant X
The X-E-planes to the left (small C0) show model 3 and the X-E planes to the right (large C0) show model 4
Figure 7. 2D graph that is the projection of the surface plot in Figure 6
Dashed black lines are lines of constant X
The best fit between the data points and Eq. 4 is obtained for a slightly different value than the one for k in the calculations to obtain Figure 6
We denote the related new parameter by k*
and its best fit is k* = 3.25 ppm m3/Wh
where SIE (specific energy density, sometimes denoted as beta in literature) is the engineering constant for a specific process, used in literature. SIE is the specific input energy, defined as the energy density needed to obtain a 1/e reduction of the pollutant concentration. We can notice the following: Eq. 4 has a power series expansion that for small arguments ε, ε = (k*.E/C0), that simplifies to Eq. 6
Furthermore, it can be noticed that Eq. 5 is the analogue of Eq. 4 for SIE = C0/k*
This latter observation shows that the model based on an SIE value can only be used if C0 is constant during the test
and that the actual SIE value depends on the value of C0 of the specific test
Moreover, these findings show that the model according to Eq. 4 combines both former models given by Eqs 5, 6
The 3D graph of Figure 6 was made to show the global behavior of the implicit solution of Eq. 1. The axes ranges were chosen in accordance with the ranges during the described measuring campaign. The measuring data are superimposed. The figure also clearly shows the models 3 and 4 of Eq. 5 (small C0 X-E-plane) and 6 (large C0 X-E-plane)
Testing was performed during a project for plasma assisted odor reduction at an animal feed plant
The described 20 kW microsecond DBD system was fed with a flow that was branched off from the main flow
The DBD system has the earlier mentioned rest-ozone reactor as the permanent post-processing unit
The industry plant was equipped with a plasma injector system fed into the main flow
far behind the branch-off location for the DBD system
This injector device was running permanently
Results of GCMS and odor measurements at an animal feed production facility
We compared the concentration in the input of the two considered plasma systems with the concentrations in the output of the DBD-Ozone reactor system and with the concentration in the output far behind the plasma injector system
Odor reductions of up to 91% were achieved with the DBD machine
The injector machine showed odor reductions of up to 90%
The product with the highest protein content (B) has the highest odor reduction
an energy density setting for the DBD system significantly higher than that of the plasma injector machine does not lead to significantly more odor reduction by the DBD system
The project proved that the investigated cold plasma DBD machine functions well and reliably during long times of operation
We were able to perform extensive measurements and analysis of the performance of a 20 kW DBD machine for the industrial odor emissions of an animal feed plant
The plasma injector machine showed odor reductions of up to 90%
Two animal feed products (A and B) have been tested
For product A there is no clear correlation between the reduction of total VOC (volatile organic compounds) concentration and the reduction of the odor concentration
For product B there is a slightly positive correlation between total VOC reduction and the odor reduction
an energy density setting for the DBD system significantly higher than that of the plasma injector machine does not lead to more odor reduction by the DBD system
A higher energy density does lead to more VOC reduction
and its interaction within the complex of particles-VOCs-SVOCs-oxidation-water
semi-volatile organic compound) have consequences for the performance
Fine dust removal following the production process should be at a higher rate than present to prevent contamination of the DBD machine
an injector system does not pollute from fine dust because the injector plasma source is not in contact with the process air
VOC clustering into aerosols by ozone and radicals can in theory also bind the odorous VOCs
This possible mechanism could in theory mask odorants
The water vapor condensation also leads to interactions with VOCs
This system of particles-VOCs-oxidation-water can mask or can cause odors and can also mask and cause VOCs
Ad hoc solutions have been found for the nuisance caused by condensation of water by adding water conduits and by temperature management of the DBD machine
the DBD machine must be kept at a temperature near or above the dewpoint of the exhaust gas of the plant
The ideal location of the full-scale DBD machine is therefore in line with the chimney
The 20 kW microsecond system in combination with the ozone reactor placed behind the plasma reactor, has been tested for emissions from a hot mix asphalt manufacturing facility and for effectiveness of the rest-ozone reactor. As in Section 4.1
the ozone reactor is the post processing device that employs the rest ozone from the microsecond plasma system
The emissions being tested contain polycyclic aromatic hydrocarbons (PAH)
Naphthalene is the major constituent of the PAH
We measured total VOC content with a three-channel FID (flame ionization detector) setup
Channel 1 measures the VOC content in the flow from the stack of the asphalt plant
Channel 2 measures the VOCs after plasma process
Channel 3 measures the output gas from the ozone reactor
The results are shown in Figure 9 and can be described as follows
Time records of the conversion X for the full process (DBD plus Ozone reactor) and for the Ozone reactor alone for two different Asphalt products
(A) The process 17/11: We see a conversion larger than 40% under wide spectrum of parameters
The post-processing conversion of this device alone is up to 55%
(B) The process 18/11: We see a total conversion of up to 59%
The post-processing device alone converts up to 40%
It turns out that the product 18/11 is more difficult to convert
the total conversion X and the share in it by the DBD-reactor increase with energy density E
During the time from start and end of a tests we notice a time delay effect between settings of the energy density and the response seen in the conversion
In parallel we notice a background conversion that possibly can be attributed to capture of PAH by aerosol formation around mist droplets
We should keep in mind these uncertainties in the following summary:
At an energy density of 17 Wh/m3 we see a conversion of 69% on total VOC for process 17/11
At an energy density of 56 Wh/m3 we see a conversion of up to 78%
On all measurements we see a conversion larger than 40% under wide spectrum of parameters
For the process 18/11 we see a total conversion of up to 59%
During operation of the microsecond plasma machine we encountered a problem due to water vapor condensation if reactors and piping cool down below the dewpoint temperature of the exhaust gas of the plant
a demister should be used in future as a supporting solution
For a range of input parameters, the total conversion was measured and documented. We collected 82 data points, for C0, the input concentration, and for the accompanying output concentration CN. The results have been summarized in Figures 5–7
Testing was performed for odors/VOCs from processing manure into fertilizers
We applied the 5 kW ns plasma machine
A small post processing device was connected the output of the machine
It is an activated carbon filter of 0.45 m3
Odor was monitored by a certified laboratory
Total VOC content was measured by the Mulitrae-Lite PID (photo-ionization detector) device
The tests were done during a 1.5-h (run1) and a 4-h run (run2). The results are summarized in Table 2
Results of tests with the nanosecond system on odor and VOC conversion at a facility that processes manure into fertilizer
The tests prove that odor reduction is effective for a manure processing plant by application of a nanosecond plasma machine in combination with a small carbon filter
Extrapolating the energy density to the full exhaust flow of 100,000 m3/h of the plant
we calculate a power need of 280 kW for the plant
This number fits in the range of the other power needs of the plant
The nanosecond plasma system was applied at a manure processing facility. The product of the process is compost. We applied the nanosecond cold plasma system (Winands et al., 2006)
The VOC samples were collected by Pra-Odournet BV and analyzed by GC-MS
Various combinations of conventional processing and cold plasma processing were investigated
It turned out that the certified odor measurements only partially reflect the results of the chemical measurements
The case acid scrubber nearly off in combination with cold plasma at its high mode (3.2 Wh/m3) has a good performance. These results are summarized in Table 3
Results of tests with the nanosecond system on odor and VOC conversion at a facility that processes manure into compost: The case acid scrubber nearly off in combination with cold plasma at its high mode (3.2 Wh/m3)
The case acid scrubber fully on and cold plasma at its medium mode (2 Wh/m3) has a rather mixed performance
but the VOC conversion has turned into VOC production
Results of tests with the nanosecond system on odor and VOC conversion at a facility that processes manure into compost: The case acid scrubber fully on and cold plasma at its medium mode (2 Wh/m3)
In the drive towards industrialization of the pulsed plasma technology
two aspects are important: energy efficiency and solid-state technology
Both these topics will be addressed in this section
where we look towards future implementations of pulsed plasma systems for industrial air cleaning
Figure 10. (A) Ozone production efficiency as a function of the applied voltage and rise time in a 50-mm diameter, 1-m long, coaxial pulsed plasma produced by the sub-nanosecond pulse source. (B) Overview of ozone generation yields and concentrations for different experiments done in Eindhoven. The <10 ns results are those performed with the sub-nanosecond pulse source. The other results are those of systems such as shown in, e.g., Figures 1, 2
An overview of results from pulsed corona systems from Eindhoven is shown in Figure 10B. The results show that while the industrial nanosecond system (from Figures 1, 2) performs very well
it is outperformed by the sub-nanosecond pulse source
the sub-nanosecond pulse source is very much a lab prototype using an oil spark gap
the aim is to achieve the results of the sub-nanosecond pulse source
but then with a pulsed power system that lends itself for commercialization
One such a system would be a solid-state system
Figure 11. (A) The 20-kV solid-state IMG. (B) Some example waveforms (van Oorschot and Huiskamp, 2023)
In this paper we presented the principle of cold plasma processing
The developed apparatus for VOC abatement performed very well. Tests conducted on VOC and odor removal at industrial sites in Netherlands proved that in some cases, up to 99% reduction is achievable. For the PAH Naphthalene, being a hard to convert VOC, a conversion of 75% could be obtained, which is a promising result. To summarize the different treatment methods and results, the key parameters of the reported methods and the existing injection method are given in Table 5
Case numbers refer to the case numbers in the section headings
and at an electric energy cost of 0.1 € per kWh)
The global processing behavior has been analyzed theoretically and experimentally
the pulsed plasma process behaves according to the Lambert function
We showed that existing processing models have a common ground in the Lambert function
The argument of the Lambert function in the case of plasma processing
is a combination of input pollutant density C0 and energy density E
A workable approximation for this Lambert function is an exponential function of the argument E/C0
This functionality was already given by Masuda in 1986 as a fit to his experimental data
Synergy in four types of application areas
The raw data supporting the conclusion of this article will be made available by the authors
The author(s) declare that financial support was received for the research
and Dutch Municipal funding from the City of Helmond
The authors gratefully acknowledge the support from TU/e
and the City of Helmond and the valuable contributions from P.F.M
The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations
Any product that may be evaluated in this article
or claim that may be made by its manufacturer
is not guaranteed or endorsed by the publisher
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Received: 14 February 2024; Accepted: 17 May 2024;Published: 07 June 2024
Copyright © 2024 Van Heesch, Huiskamp, Yan, Beckers, Smulders, Winands, Lemmens, Blom, Segura, Hoeben, Van Paasen, Van Oorschot, Bonkestoter, Van Den Brand, Hennink, Smulders, Pemen and Van Der Laan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use
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1958 to Eldon and Marjorie (Rasmusen) Schmidt in Tyler
Minnesota and grew up on the family farm near Lake Benton
she and her family moved into town and Jackie attended school while also working at her Mom’s restaurant
working for a number of years in upholstery at Bayliner Marine in Pipestone
Jackie began working in healthcare and enrolled in school Southwestern Technical College for administration and accounting
Jackie took a job in billing support at the Pipestone County Medical Clinic
She enjoyed the people she worked with through the years
Jackie died suddenly as the result of a heart attack at the age of 64 years
She was currently a member of Faith Community Church in Pipestone
She had a gift of taking something ordinary and somehow turning it into something beautiful
enjoyed working together on their home and took great pride in their yard
She was always very fashion focused and had a shoe collection that many ladies would envy
Jackie loved her two children and later loved spending time with her grandkids and attending their various sporting events and activities
Jackie loved her family with her whole heart and let it be known that they were her pride and joy
Jackie is lovingly survived by her husband
Washington; and other relatives and friends
Eldon and Marjorie Schmidt; and her mother-in-law Ethel Heesch
April 14th at Copperleaf in Willmar. His funeral will be 1:00 pm
April 19th at Good Hope Lutheran Church in Titonka
Iowa with visitation one hour prior to the service. Interment will be in the church cemetery. Funeral arrangements are with Harvey Anderson Funeral Home in Willmar
Virgil was born on the family farm on November 11
the son of Nick and Charlotte (Geisking) Heesch
He was baptized and confirmed at Good Hope Lutheran Church and attended Titonka Consolidated School. Following his schooling
he worked on the family farm when he met Jeanette Swalve. They were married on October 13
1941 at The Little Brown Church in the Vale in Nashua
Iowa. They made their home on the farm in Ledyard
they moved to Forest City in 1980 where he began his “second career” driving school bus. He drove for Forest City School
driving a regular route and then began driving for the girls softball team. He made many close relationships with players and coaches. He retired at the age of 86
Minnesota to be closer to his family. He maintained his own apartment till he was 98 when he finally moved into Copperleaf Assisted Living.
Paul (Marlene) Heesch of Waite Park and Sheryl (Phil) Mulder of Prinsburg; six grandchildren
two sisters-in-law and many nieces and nephews
Duane Sheldahl in 2007 and Herb Harms in 2016; great grandson
Noah Mellema in 2010; two brothers and two sisters
a hardworker and providing a Christian Home
A Juneau County school district will ask voters for a third time to approve a referendum needed to continue operating beyond the next two years
The School District of Mauston will put a referendum on the Feb. 18 ballot asking voters to allow the district to exceed the state-imposed revenue limit by $1.75 million annually for the next four years
It’s the same amount that voters narrowly rejected during the November election
which failed by less than 2 percentage points
The community overwhelmingly rejected the district’s first referendum of $2.25 million last April
Without the additional funding, district leaders said they will be unable to operate Mauston schools past the 2026-27 school year. The school board voted last month to consider dissolving the district over the lack of funding
The board also approved myriad budget cuts for next school year
including closing an elementary school and cutting all sports
School board vice president Mike Zilisch said the group decided to bring the referendum back right away instead of waiting for the spring election in April
He said it hopes to prevent families and staff from leaving the district
which would further complicate the district’s budget projections
“April is getting to that point where students and family are going to start looking at options for the next school year
“We felt February was the most prudent (time) to get that through
to be able to give people enough time to prepare if
District leaders say they have continued to battle misinformation about the budget
including some claims that the district does not need the additional funding and
But Superintendent Joel Heesch said his district is far from alone in their budget struggles
He said almost all of the state’s school districts have gone to referendum to cover increasing operating expenses
“I find it hard to believe that 90 percent of the school districts in the state are overspending or misappropriating funds,” Heesch said
“I know that that’s not the case
So I would like people to be able to take a step back and see the root of the problem is not your local school district
it’s the funding formula that we have at the state (level).”
Heesch said state lawmakers have acknowledged to him that the state’s funding formula isn’t working
But he said there appears to be little interest in fixing the system to help schools keep pace with rising costs
Heesch said the district will not be able to get another question on the April ballot
He said they will continue to answer the community’s questions and offer public listening sessions ahead of the next vote to try to gain more support
Board of Regents of the University of Wisconsin System and Wisconsin Educational Communications Board
Home / Sports / Iowa High School Sports
Solon senior will be relied on even more to help round out team scores this season
SOLON — Brennan Heesch is not new to the Solon boys’ golf lineup
the Solon senior has been a mainstay in it since he joined the program
Heesch was part of three straight Class 3A state tournament teams
His final campaign will be a little bit different
serving as one of the Spartans leaders behind all-state performers Isaiah Zoske and Jack McCarty
“There’s more pressure to shoot good scores and I feel like I have shot good scores
I like it a lot more than not having expectations
Heesch has been an important contributor for those successful Spartan teams and will be relied on even more to help round out team scores this season. He helped Solon open the season Monday with a 151-166 dual victory over host Mount Vernon at Kernoustie Golf Club
“He’s been a key cog in our teams over the last few years,” Solon Coach Adam Stahle said
“He’s going to be critical for any success that we have this year.”
He averaged 38.29 for nine holes last season and carded 80.83 per 18 with a 41.02 combined adjusted average (which combines all competition and factors in course difficulty)
Stahle noted that Heesch can get overshadowed by Zoske’s and McCarty’s accolades but he provides stability to the Spartans with his experience
Heesch has played in stressful competition during major tournaments and knows how to handle it
He leads by example and demonstrates a strong work ethic
“He adds that consistency,” Stahle said
I know there are a lot of kids that look at him and see what they want to try and get to and emulate his game
He’s not going to be the first to lead the charge and say a lot
He works extremely hard and dedicates a lot of time to it.”
he can usually be found playing at Lake MacBride Golf Course
“It is something I do a lot,” Heesch said
all I’m pretty much doing is golfing
It (time) depends on how busy the course is
The biggest emphasis in the offseason was his mental game
Heesch possesses confidence in his ability thanks to good rounds posted during the summer and in last season’s sectional and district meets
He said he knows that he can post low scores and it is a matter of doing it during the varsity season
“It’s all about believing in yourself and having trust in yourself,” Heesch said
“A lot of (mental focus) is on the course
It’s forgetting about the last shot and focusing on the next.”
Heesch set his sights on a specific goal this year
He wants to add all-Wamac Conference honors to his resume and is determined to earn multiple medals — team and individual — in all three postseason meets
A feat he managed in sectional and district competition as a junior
the goal is a state championship,” Heesch said
“I think we lost a few people but we definitely have enough good people to get there and win.”
The Spartans have about 65 golfers out at all levels
Solon played well and still identified things to improve
preparing for a tough schedule in a stacked Wamac that had three state-qualifying teams a year ago
“They were able to put up pretty good scores,” said Stahle
adding the Wamac could have three to four teams at state this year
We lost three seniors that were on the team that played a lot of golf
The thing that is really cool behind it is we have a lot of kids who patiently waited their time
For them to get out there — varsity and JV overall — to play like we thought they were able was very encouraging to see.”
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Wes will be deeply missed by his seven children
TX; fifteen grandchildren; twenty-six great grandchildren; one great-great grandchild; numerous nieces and nephews; sister-in-law
I will miss wes,,I saved all my soda cans for him he would walk by with JD and collect them a couple times a week
wes was a very sweet man with a heart of gold..to wes’ family may you keep him in your heart and he will be with you for ever,,as a lot of us will do,,,May you Rest In Peace Wes with JD
and website in this browser for the next time I comment
Metrics details
Overexpression of prostate-specific membrane antigen (PSMA) on the vasculature of triple-negative breast cancer (TNBC) presents a promising avenue for targeted endogenous radiotherapy with [177Lu]Lu-PSMA-I&T
This study aimed to assess and compare the therapeutic efficacy of a single dose with a fractionated dose of [177Lu]Lu-PSMA-I&T in an orthotopic model of TNBC
Rj:NMRI-Foxn1nu/nu mice were used as recipients of MDA-MB-231 xenografts
The single dose group was treated with 1 × 60 ± 5 MBq dose of [177Lu]Lu-PSMA-I&T
while the fractionated dose group received 4 × a 15 ± 2 MBq dose of [177Lu]Lu-PSMA-I&T at 7 day intervals
Tumor progression was monitored using [18F]FDG-PET/CT
Ex vivo analysis encompassed immunostaining
Tumor volumes were significantly smaller in the single dose (p < 0.001) and fractionated dose (p < 0.001) groups
Tumor growth inhibition rates were 38% (single dose) and 30% (fractionated dose)
Median survival was notably prolonged in the treated groups compared to the control groups (31d
[177Lu]Lu-PSMA-I&T decreased the size of viable tumor areas
that [177Lu]Lu-PSMA-I&T binds specifically to the tumor-associated vasculature
This study highlights the potential of [177Lu]Lu-PSMA-I&T for endogenous radiotherapy of TNBC
[177Lu]Lu-PSMA-I&T was produced by a GMP approved clinical routine procedure primarily used for patient care
a cassette synthesizer type GRP 3 V (Scintomics
Germany) dedicated to the radionuclide (SC-05 for 177Lu using acetate buffer during labeling)
Germany) was transferred to the reactor containing precursor PSMA-I&T and acetate buffer
the solution was quenched by a saline solution containing DTPA
Radiochemical purities and yields were > 95% (measured with radio-HPLC)
France) was purchased with a volume activity of 600 MBq/mL at the time of calibration
Germany) supplemented with 10% fetal bovine serum and 1% penicillin/streptomycin (Pan Biotech
Cells were tested biweekly for mycoplasma contamination
France) at 6–8 weeks of age were used for orthotopic TNBC xenograft implantation
Animals were housed at 20–24 °C in a 12 h daylight cycle and given at least 7 days for acclimatization before the start of the experiment
5 × 106 MDA-MB-231 were resuspended in a 10 µL culture media/10 µL matrigel mixture (Corning
Mice were inoculated in the mammary fat pad on the right flank
Tumor growth was monitored daily using caliper measurements
Tumor volume was calculated daily according to the following formula assuming an ellipsoid shape:
In addition to the daily caliper measurements
image analysis of [18F]FDG-PET/CT based tumor volumes was blinded to avoid bias
Animals were finalized upon reaching a humane endpoint for the therapy study (i.e.
15 mm tumor diameter or 1500 mm3 tumor volume
6 mice were not considered for the quantification due to reaching an unusual early end point (tumor diameter 15 mm
Animals were randomly distributed into 3 groups: Control (n = 6)
[177Lu]Lu-PSMA-I&T single dose (60 MBq) (n = 7) or fractionated dose (4 × 15 MBq) (n = 5)
Randomization was done based on equivalent distribution of tumor volumes
Under 1.5–2.5% isoflurane in medical grade compressed air at 0.8 L/min
the lateral tail vein was injected with [177Lu]Lu-PSMA-I&T (single dose: 60 ± 5 MBq once
fractionated dose: 15 ± 2 MBq every 7 days for 4 weeks) diluted with 0.9% NaCl to a total volume of 50 µL
The administered dose was calculated by subtraction of decay-corrected syringe activity post-injection from pre-injection activity
Initially the animals received an intraperitoneal injection with 10 MBq of [18F]FDG diluted with 0.9% NaCl to a total volume of 100 µL; 30 min later
each animal was placed on the scanner bed and the CT scan was initiated under 1.5–2.5% isoflurane in medical grade compressed air at 0.8 L/min
All mice were imaged with a small animal PET/SPECT/CT system (Tri-umph®II
however only the PET and CT modalities were used for this study
The exposure settings used were as follows: 130 uA
and 360° rotation with 512 views; the duration of the CT scans was ~ 5 min
A dynamic 30 min PET scan was initiated at the end of the CT scan
The CT had an axial field of view of 91.1 mm and a PET of 112 mm
the isoflurane concentration was adapted to achieve a respiratory rate between 75 and 50 breaths per minute
where μw is the linear attenuation coefficient of the water and μt is the linear attenuation coefficient of the tissue
The PET data were reconstructed using a 3D ordered-subset expectation maximization (i.e.
OSEM-3D with three iterations and eight subsets) with a maximum a posteriori probability algorithm (30 iterations) into a 240 × 240 × 192 image matrix (resulting in final voxel dimensions of 0.25 × 0.25 × 0.597 mm)
and CT scatter correction were applied to all PET reconstructions
The PET images were automatically aligned to the CT using a custom-made transformation in PMOD software package from a capillary phantom
To exclude the bed and other objects from the CT image
an automatic isocontour detection around the mouse using -500 HU as a minimal threshold on the coronal view was used
The newly created images were used to show exemplary CT by capturing with a window from − 1000 to + 1000 HU
PET images were captured using a window from 0 to 2.6 SUVbw
the images co-registered PET/CT scans were used
small intestine) were fixed with 4% PFA overnight at 4 °C
the organs were kept for 2–3 days at 4 °C in 30% sucrose
Cryosections (6 μm) of tumor and organs were made using a cryostat (Leica
The TUNEL staining procedure was carried out with the in situ cell death detection kit accordingly to the manufacturer’s instructions (Roche
Nuclei were counterstained with DAPI and slides were mounted in mowiol
permeabilized for 5 min with 0.1% triton/PBS
and blocked for 90 min with 5% goat serum at room temperature
Samples were incubated overnight at 4 °C with primary mouse α-PSMA (Abcam
sections were incubated with goat α-mouse Alexa Fluor 488 (Thermo Fisher Scientific
1:1000) and goat α-rabbit Alexa Fluor 555 (Cell Signaling
1:1000) antibodies for 1 h at room temperature
Germany) staining was applied for 3 min and the cells were mounted with mowiol
Images were acquired with an Imager Z.1 microscope (Zeiss
All following steps were performed at room temperature
Sections were immersed with PBS and rinsed with running water followed by incubation in Haematoxylin (10 min)
Sections were rinsed again with running water and subsequently incubated in Eosin (1 min) followed by washing twice with running water for 5 min
xylol: 1 and 10 min) were performed and tissues were mounted in pertex (Medite
After the complete decay of injected 177Lu
tumor cryosections were washed 3 × with PBS and were incubated with 2 MBq [177Lu]Lu-PSMA-I&T per tissue for 4 h at room temperature
the slides were coated with NTB solution (Kodak
USA/NY) and incubated at − 20 °C in the dark
After 6 days the slides were equilibrated for 30 min at room temperature and incubated in developer (Tetenal
and destilled water (10 min) and stained with H&E
Tumor cryosections were washed with PBS and incubated with 2 MBq [177Lu]Lu-PSMA-I&T per tissue for 4 h at RT
sections were exposed on plates (Fuji Film BAS-IP SR 2025
Germany) for 24 h at room temperature and scanned using the Typhoon FLA 7000 (GE Healthcare
USA/IL) to obtain an image of the [177Lu]Lu-PSMA-I&T distribution
All statistical analyses were performed using the Graph-Pad Prism software (Version 8)
Kaplan–Meier survival curve was analyzed with the log-rank test
Comparison of mean values was analyzed with ANOVA and Tukey’s post-hoc correction after testing for normal distribution
A Schematic therapy regime of single dose (pink) and fractionated dose (violet) of [177Lu]Lu-PSMA-I&T
Tumor growth was monitored weekly via [18F]FDG-PET/CT (blue arrows)
single dose (pink) and fractionated dose therapy (violet) animals (n ≥ 5); ** p = 0.002
C Waterfall plot analysis of tumor volumes on the day of finalization
Volumetric differences were significant for the single dose (** p = 0.003) and fractionated dose (** p = 0.001) treated animals when compared to the control group
A Tumor growth analysis comparing the time period (in days) until reaching 200% of the initial tumor volume (TV) in control and therapy receiving groups (n ≥ 5); ** p = 0.008)
B Kaplan–Meier survival of single dose and fractionated dose group compared to the control
Representative PET/CT images of [18F]FDG distribution 30 min post injection in control (A–D)
and fractionated dose (I–L) group before (− 1d) and 6 or 27 d after therapy
Colored images represent PET/CT images with a SUVmax of 2.6 and HU range from − 1000 to 1000
Black and white images represent PET with a SUVmax of 2.6
TUNEL staining (green) of tumor and organs of control (A
Nuclei were counterstained with DAPI (blue)
The staining solution without enzyme served as negative control (S–U)
Microscopic evaluation of HIF1α (red) expression in tumor tissue from control (A
The black box inside the schematic tumor tissue illustrates the location of interest
Evaluation of PSMA expression in TNBC tumors using [177Lu]Lu-PSMA-I&T AURA (A–C; zoom-in: D–F) with corresponding H&E staining (G–I); and [177Lu]Lu-PSMA-I&T mAURA (J–L) with corresponding PSMA/CD31 immunofluorescence staining analysis (M–R)
despite the fact that the necrotic core contributes to the overall tumor volume
the vital tumor tissue (indicated by [18F]FDG uptake) decreased under treatment with [177Lu]Lu-PSMA-I&T
The corresponding H&E images further demonstrate
that the tumor tissue of the treated groups contains less viable regions compared to the control group
assuming that [177Lu]Lu-PSMA-I&T efficiently decreased the blood supply and thus the overall cell viability
Further we could prove the presence of PSMA on the tumor-associated blood vessels via mAURA and immunostaining
verifying the expectation that the tumor growth inhibition is a direct consequence to the irradiation of the tumor-associated vasculature
These radiation effects might contribute to the therapeutic potential of [177Lu]Lu-PSMA-I&T
Considering the predominant PSMA expression on the vasculature
[177Lu]Lu-PSMA-I&T destroys the tumor-associated endothelial cells and therefore stops or decreases the blood supply to the tumor
The prognosis of patients diagnosed with TNBC is poor and due to the lack of therapeutic options
targeted strategies are urgently searched for
this is the first in vivo evaluation of [177Lu]Lu-PSMA-I&T therapy in TNBC mice comparing a single dose and a fractionated dose approach
It is clearly demonstrated that [177Lu]Lu-PSMA-I&T inhibits tumor growth and improves survival
[177Lu]Lu-PSMA-I&T accumulates in the blood vessels and thus acts as an anti-angiogenic radio therapeutics
Further studies need to address the dosimetric aspect to improve the therapeutic effect of the fractionated dose
it would be interesting to test if a combination of [177Lu]Lu-PSMA-I&T and chemotherapy could enhance the tumor growth inhibiting effect
We are aware that experiments regarding biodistribution and toxicity are not included in this study
[117Lu]Lu-PSMA-I&T is a very common and frequently used radiotracer
therefore the biodistribution and toxicity were already sufficiently evaluated before
Especially regarding the amount of animals
one should use as much as necessary and as little as possible
In this first in vivo attempt using [177Lu]Lu-PSMA-I&T in TNBC
we used relatively small groups of n = 8 mice per group
After demonstrating efficacy of the treatment
the n-number can be increased for further optimization of the therapy in future studies
we propose to perform a dosimetry study to calculate the optimal injected dose
Another limitation is the high amount of necrosis formation in the MDA-MB-231 xenograft
which is characteristic for this cell line
assuming that the vascularization of the tumor is moderate
a combinational approach with [117Lu]Lu-PSMA-I&T and chemotherapeutics could be useful to increase the efficacy of the treatment
All data generated or analyzed during this study are available from the corresponding author
Triple-negative breast cancer: a review of current curative intent therapies
Recent advances in therapeutic strategies for triple-negative breast cancer
Stem cell marker aldehyde dehydrogenase 1 (ALDH1)-expressing cells are enriched in triple-negative breast cancer
Triple-negative breast cancer molecular subtyping and treatment progress
Lymphatic and blood vessels in basal and triple-negative breast cancers: characteristics and prognostic significance
Efficacy and safety of bevacizumab in combination with docetaxel for the first-line treatment of elderly patients with locally recurrent or metastatic breast cancer: results from AVADO
phase III trial of chemotherapy with or without bevacizumab for first-line treatment of human epidermal growth factor receptor 2-negative
locally recurrent or metastatic breast cancer
phase III trial evaluating the efficacy and safety of bevacizumab in combination with chemotherapy for second-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer
Antiangiogenesis therapy for breast cancer: an update and perspectives from clinical trials
Prostate-specific membrane antigen in breast cancer: a comprehensive evaluation of expression and a case report of radionuclide therapy
Detection of prostate-specific membrane antigen on HUVECs in response to breast tumor-conditioned medium
Induction of PSMA and internalization of an Anti-PSMA mAb in the vascular compartment
The potential of PSMA as a vascular target in TNBC
[177Lu]-PSMA-617 radionuclide treatment in patients with metastatic castration-resistant prostate cancer (LuPSMA trial): a single-centre
Lutetium-177 labelled PSMA targeted therapy in advanced prostate cancer: current status and future perspectives
Renal safety of [177Lu]Lu-PSMA-617 radioligand therapy in patients with compromised baseline kidney function
CBCT-based bone quality assessment: are Hounsfield units applicable
Interfering with tumor hypoxia for radiotherapy optimization
Therapeutic radionuclides: biophysical and radiobiologic principles
Characterizing the metabolic heterogeneity in human breast cancer xenografts by 3D high resolution fluorescence imaging
Characterization of a murine xenograft model for contrast agent development in breast lesion malignancy assessment
PSMA expression in the Hi-Myc model; extended utility of a representative model of prostate adenocarcinoma for biological insight and as a drug discovery tool
Safety of PSMA-Targeted Molecular Radioligand Therapy with 177Lu-PSMA-617: Results from the Prospective Multicenter Phase 2 Trial RESIST-PC (NCT03042312)
177Lu-PSMA-I&T radioligand therapy for treating metastatic castration-resistant prostate cancer: a single-centre study in East Asians
Expression of hypoxia-inducible factor 1: mechanisms and consequences
Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodelling
and sirtuins in cancer initiation and progression
Modulation of glutathione promotes apoptosis in triple-negative breast cancer cells
PSMA brings new flavors to PI3K signaling: a role for glutamate in prostate cancer
Early PSA change after [177 LU]PSMA-617 radioligand therapy as a predicator of biochemical response and overall survival
68Ga-PSMA-11 PET/CT-derived metabolic parameters for determination of whole-body tumor burden and treatment response in prostate cancer
Angiogenesis inhibitors in cancer therapy: mechanistic perspective on classification and treatment rationales
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The authors are grateful to Susanne Allekotte for technical support and Prof
Barbara Klinkhammer for the provision of H&E images
Open Access funding enabled and organized by Projekt DEAL
This research was funded by Deutsche Krebshilfe (Project Number: 70113779 and 70113780) and Deutsche Forschungsgemeinschaft in the framework of the Research Training Group ‘Tumor-targeted Drug Delivery’ (Project Number: 331065168)
Department of Radiology and Nuclear Medicine
Maastricht University Medical Center (MUMC+)
School for Cardiovascular Diseases (CARIM)
FMM is medical advisor for Nanomab Technology Ltd
and Advanced Accelerator Applications (AAA) GmbH
He has recently received institutional grants from Nanomab Technology Ltd.
Furthermore he has an interventional research contract with CURIUM
All animal experiments were approved by a German competent authority (Landesamt für Natur
Umwelt und Verbraucherschutz Nordrhein-Westfalen) for compliance with the Animal Protection Act
in conjunction with the regulation for the protection of animals used for experimental and other scientific purposes
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations
unless otherwise stated in a credit line to the data
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DOI: https://doi.org/10.1186/s13058-024-01787-9
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1995 in Sioux Falls to Arlen and Betsy (Teerink) Heesch
She was raised and attended school there and graduated from Washington High School in 2014
She attended college in Minneapolis at the Minnesota Art Institute
Ashley was a free spirit that was learning who she was and blossoming beautifully
She loved her truck and spent hours driving around and listening to music in it
Ashley also liked “Anime” and “Monga” and watched many movies and read books involving the Japanese art
Her friends were very important to her as well and hangin’ at Fryin’ Pan was one of her “things.” She will be deeply missed by everyone who knew her
Ashley was greeted in Heaven by her one sibling
a go fund me account has been established @ http://www.gofund.me/ashleyheesch
Our deepest sympathy to you as you go though this tough time
I know that Grandpa Jesse was waiting for you to wrap his arms around you…life will never be the same without the two of you…you both taught us what unconditional love was all about…you shared your quick wit and humor to brighten our days…your laughter and shared moments were a joy to behold…I will always hold those moments close to my heart
May the God of all comfort give you the strength to endure the pain in your hearts at this time
Keep the hope alive of being together again in the near future
Please extend our deepest sympathies to your family
We were fortunate to know the Bears chefs when we lived in Hartford and always look forward to your welcoming smile at McDonalds
My heart goes out to everybody who has lost this beautiful light in their lives far too early
I loved going to work to see your hugh smile when you walked thru the door
I also loved the after work trips to fry’n pan breakfasts
May you RIP and god be with you on your next resting place in HEAVEN
will celebrate their 50th wedding anniversary on Saturday
Cards may be sent to them at 1322 Eighth Ave
Their family includes Jayson and Amy Heesch
They have 12 grandchildren and one great-granddaughter
Janet Malloy and Jerry Heesch were married April 22
at Holy Rosary Catholic Church in Fort Dodge
LLC | https://www.messengernews.net | 713 Central Ave.
Pella Regional Health Center has named Chris Heesch
to the role of Director of Clinic Services
This position is responsible for the direction and coordination of Pella Regional’s medical clinics in Pella
Heesch was most recently employed at Mayo Clinic Health System in Red Wing
He provided leadership and management to all aspects of clinic operations including Family Medicine
His previous experience includes working as a Registered Nurse at Sandford USD Medical Center in Sioux Falls
.st1{fill-rule:evenodd;clip-rule:evenodd;fill:#2a2a2a}By Douglas Perry | The Oregonian/OregonLiveThe bombings started near Mount Hood in the early fall of 1974
The huge explosions made the ground jump even miles away -- and caused three Bonneville Power Administration transmission towers to topple
sending three additional massive towers crashing to earth
but the big bangs spread fear through the region
the Bonneville Power Administration released a letter from “J
(Reorganized Veterans of Viet Nam).” The letter demanded $1 million
had “the men and equipment to keep as many towers down as is necessary to force compliance with our demands.”
One letter stated that they would cause an enduring blackout in Portland and set fire to the Bull Run watershed if authorities attempted to capture the men the group planned to send to pick up the ransom
The letter called the bombings so far a “demonstration project.”
was not a criminal organization but simply “demanding just compensation from the government.”
This was an era of politically motivated bombings in the U.S
There were more than 2,500 of them during an 18-month period in 1971-72
Hawker -- the pseudonym was a nod to the Jayhawkers
the determined anti-slavery guerrillas in Kansas and Missouri during the Civil War period -- sent off another “impeccably typed” letter on Tuesday
stated that the group was temporarily suspending the threat against the “U.S
Government” because of poor weather conditions
landing in the mailbox of a Portland teacher
Postal Service wasn’t getting the job done
Hawker began communicating with the FBI through citizen’s band (CB) radio
The bomber used a duck call and Morse code to maintain anonymity
but it ultimately proved to be the “BPA Bomber’s” undoing
Forty-five years ago this month, FBI agents used mobile “direction finders” to zero in on the CB radio signal
34-year-old Beavercreek truckdriver David W
When Sheila turned around in her seat and noticed an official-looking car carrying official-looking men right behind them
The agents pulled over the car and searched it
finding a CB radio and a duck call that the agents determined “sounded like the transmissions we had been receiving.”
FBI agent-in-charge Julius L. Mattson added in a statement to the press: “We also found in Mrs
Heech’s purse a 22‐caliber derringer pistol
David Heesch immediately confessed to the bombings
and he admitted his actions had nothing to do with revolutionary politics
He explained he had recently lost his long-haul driving job and was desperate
David was sentenced to 20 years in federal prison
He would spend nearly five years behind bars before being paroled
ended up serving 11 months in prison after originally receiving a 10-year sentence
The couple remained married -- and very much in love
David, who became a TriMet bus driver after serving his time, died in 2006. Eight years later, Sheila told Sandy Post columnist Paul Keller that she and their children still missed him “very much.” And she expressed admiration for her husband
including his ability to teach himself how to handle explosives for that long-ago criminal sojourn
“He knew what he was doing with that dynamite,” she said
“He knew which direction he wanted those towers to fall -- and they did.”
“David thought that if he could get that money
he would be able to spend more time with his kids,” she said of the $1 million ransom demand
Sheila told Keller that she and her husband had been very “young” when they tried to pull off their audacious extortion plot
and that their criminal actions were an aberration
She claimed the reason both she and her husband had their sentences cut was because judges recognized the kind of people they really were
“We certainly weren’t terrorists,” she said
@douglasmperry
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eight students sit with pencils at the ready
The lights are dimmed and the teacher at the front of the classroom has a worksheet projected onto the board
Looking to fill the blank space with an answer
the teacher turns to her class and asks the students what type of question would they ask to find out a person's age
Students think long and hard about the answer
the students recite their answer: "How old is she?"
This course has the look and feel of an adult basic education course for English Language Learners
This class is not provided at a school; it is in a conference room
And these learners are learning occupational English skills to help them perform their jobs successfully at GNP Co.'s chicken processing facility in Cold Spring
"This is about engaging people," said Janelle Heesch
GNP human resource manager at the Cold Spring facility
"It's an awesome opportunity to learn English and to help our employees better themselves here."
GNP's ELL course can be traced back to 2002
the program was not as definitively organized until 2006
has been working to provide limited English speakers the chance to improve their language skills to help them with both their workplace and social interactions
The class is open to all non-English speakers
"We have the biggest participation from our Somali employees
It just depends on who is looking for the opportunity."
The GNP ELL program is a 16-week course on paid time that meets every Tuesday and Thursday
in the midst of the company's shift change
"The team members either come into work an hour early or stay an hour late in order to be in this class," Heesch said
The company has made arrangements with other employees to fill the gaps while students are in class
Each employee interested in participating in the voluntary program has to complete the Comprehensive Adult Student Assessment Systems test prior to being enrolled
"It's a standardized adult basic skills test," Scott Wallner
assistant director of community education at St
Wallner said between 50 and 60 employees sign up each semester to take the test
About 22 students will be selected to enroll in the GNP ELL course
"Basic test scores have a lot to do with (the selection process)," Heesch said
Those who already have some English skills are more likely to be selected
Heesch said selection is also heavily influenced by the length of time the employee has been with the company (students typically have worked between 90 days and six months) and whether the employee is in good standing with the company on issues such as as attendance
students work together with an instructor to master some of the basic materials
and given personal instruction and group activities
A lot of the work focuses on discussion with peers and completing worksheets
But the GNP ELL program is primarily focused on helping employees improve their occupational English skills
including skills needed on the production floor
"Some of the basic pieces are that we help with forms
such as internal promotions and open enrollment (for insurance)," Heesch said
Wallner said the course also helps teach employees how to communicate with their supervisors and ask questions about their pay stubs
"We try whenever possible to use nonsensitive GNP memos and incorporate them into our lesson," Wallner said
Students also will have quality assurance lessons
where once or twice a semester processed birds will be brought into the classroom and students will have to identify if certain birds are acceptable to be sent out to consumers
"It's all really relevant to their work life at Gold'n Plump," Wallner said
"One of the things about adult basic education is there needs to be enough students to generate enough hours to make it worthwhile," Wallner said
this program has generated enough hours to sustain itself."
Overwhelming demand led GNP to convert its ELL course into a two-semester
The semesters are broken down by level of proficiency
with one semester geared toward beginners and another for intermediate and advanced learners
"The retention rate is very high," Wallner said
"Which is not always the case in a voluntary program."
GNP executives and even local lawmakers are invited to a small graduation ceremony at the end of each semester
Students are required to take a post-program CASAS test to determine if advancements have been made in their English comprehension
Wallner said most students see an eight- to 12-point jump
qualifying them to to move up at least one level on the English proficiency portion of the assessment
Heesch said the biggest success of the program has come in the employee attitudes and confidence
"We see our employees are more comfortable to step up
Heesch said about 25 percent of graduates of the GNP ELL course have been promoted within the company
"We can't speak specifically to the link," Lexann Reischl
"But we are seeing improved work performance and engagement
we are creating a better work experience and they are more involved."
Reischl said GNP covers costs of materials and invests about 5,000 labor hours annually in the ELL program
Instructors are compensated through the company's partners
But the monetary investment made by GNP is an investment both Reischl and Heesch said has been worth it
"We truly believe in our people and want to give them the opportunity to grow in their career paths," Heesch said
Reischl said the program's success is partially due to the investment GNP has committed to providing career development opportunities
we are hiring with the long term in mind," she said
"We enter into relationships with our employees
Our mindset is that we are entering a relationship
And we will invest more in the long term for the advancement and development of our team members."
The other reason for success is the positive engagement between team members
"We are so excited that all of the people (who go through this program) are excited and proud of what they have accomplished," Reischl said
Follow Vicki Ikeogu on Twitter @VickiSCTimes or call her at 259-3662
If you or someone you know is doing something innovative, creative or unique in Central Minnesota business, let us know and it could be featured here. Call Times reporter Vicki Ikeogu at 320-259-3662 or email vikeogu@stcloudtimes.com and let us know your Bright Idea
What does an occupational English Language Learner program look like? Times reporter Vicki Ikeogu had the opportunity to observe one of GNP Co.'s ELL courses and has your behind-the-scenes look how GNP is working to improve the language skills of its employees. Check out www.sctimes.com for the video
.st1{fill-rule:evenodd;clip-rule:evenodd;fill:#2a2a2a}By Brendan KirbyMOBILE, Alabama – A local doctor who accuses his former employer of firing him for exposing fraud will get his day in court
Dr. Christian Heesch, a cardiologist who worked for Diagnostic Physicians Group before his termination in 2011, recently won $4.41 million in a whistleblower suit against the medical practice
and a pair of health clinics affiliated with the hospital company
He has a separate claim against Diagnostic Medical Group alleging retaliation for his firing
District Judge Kristi DuBose to rule in its favor without a trial
arguing that Heesch had failed to demonstrate the necessary elements of a retaliation claim
But DuBose ruled this week that those are issues for a jury to decide
there are credibility and factual determinations that must be made by a jury as to why DPG terminated" Heesch
Heesch filed a lawsuit in 2011 under a provision of federal law that allows private citizens to pursue fraud claims on behalf of the federal government and then share in the proceeds of any monetary damages
He alleged that the financial compensation of doctors in the practice violated anti-kickback provision of the Stark Law
which is designed to prevent excess payments from Medicare
Medicaid and other government health programs
Heesch maintained that doctors improperly received bonuses based on the number of tests and procedures that they referred to Infirmary Health's clinics
The federal government took over the suit last year and negotiated a settlement last month in which the defendants agreed to pay $24.5 million
Diagnostic Physicians Group asked Heesch to resign on July 11
a month after he requested extensive records form the firm concerning Medicare payments
The board voted to terminate him on July 25 of that year and notified him two days later
Diagnostic Physicians Group lawyers argued that the practice did not know that Heesch was investigating fraud until December 2011 when it received a subpoena from the Department of Health and Human Services Office of the Inspector General
The lawyers also argued that the practice terminated Heesch because he was difficult to work with
But DuBose wrote that Diagnostic Physicians Group was on notice when Heesch hired a lawyer and began requesting documents
she wrote; it is sufficient that he complained directly to supervisors
(Heesch's) counsel and forensic analysis asked specifically for information on Medicare and Medicaid payments
and the billing and collection amounts on professional services separated by group member," she wrote
As to defense arguments that it had a valid reason to fire Heesch
the judge wrote that the law requires only that the plaintiff establish that his investigation of the company's financial practices was not unrelated to his dismissal
there is sufficient evidence to clear the low bar set for establishing this element," DuBose wrote
"Only two weeks passed between (Heesch's) July 13 letter expressly citing Stark violations and DPG terminating his employment."
DuBose wrote that "a reasonable jury could infer that retaliation was also a motivating factor in (Heesch's) termination
The Court finds particularly significant the timing of (his) termination; five weeks after (his) counsel requested information regarding payments covered by the Stark law and one week after (he) wrote a letter stating (his) belief that DPG was violating the Stark law."
DuBose's decision paints a picture of a rocky relationship between Heesch and his bosses
The Stark law allegations were not the first time he had butted heads with his superiors
he often submitted written complaints about work-related issues
he sent a 12-page latter t the Infirmary chief of staff expressing concerns about the catheterization laboratory
he objected in writing after the Diagnostic Physicians Group board asked cardiologists from the Heart Group to join the practice
he documented complaints regarding call coverage
he wrote about his frustration with an insurance company faxing confidential papers to a receptionist in the office
"The record plainly shows (Heesch) did not shy away from making his complaints known," DuBose wrote
Heesch's peers acknowledged that he provided quality care but made it clear he was difficult to work with at times
Colleagues sent two separate letters to the board in 2010 complaining about their working relationship with him
Heesch returned to the office several times to retrieve personal belongings
he secretly recorded conversations with his former co-workers
Attorneys for both sides quoted excerpts from those conversations to bolster their legal arguments
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Where did you grow up in Germany?I’m from the north
I think it’s my favorite city in the world
My mother’s a goldsmith and my father’s a doctor
and somebody asked me if I wanted to try out modeling and I said
why not?” I started [last] year — my mother agency is called Modelwerk in Hamburg
but I was always tall and I sometimes watched TV shows about modeling
like Germany’s Next Top Model with Heidi Klum
Do you miss a lot of school for modeling?For the spring 2013 fashion weeks
so I missed two and a half weeks of school
but my best friend told me after what I missed
there are not that many models in my city because it’s not that big
but since I do miss a lot of school sometimes
What do your parents think?They’re really proud
she watched my first show — it was the Dior Haute Couture show — she sat in front of the computer and watched the live-stream and she started crying
Tell me about Dior couture.It was my first show in my life
I was in London and then I got [an e-mail] that I should come to Paris
and I took a train and went to the casting
I’ve never seen anything like it before — it was amazing
Raf Simons was there at the casting and I really like him
What shows stood out for you last season?Of course Valentino
I really loved the music in the show and the dresses were awesome
I think it’s a good idea and I think it’s important for where we are now
And it was nice to see Karl Lagerfeld in life
I also saw the Hula-Hoop bag — the girl who carried it told me it was quite heavy
You’ve also done some editorial work. What was it like to shoot for Wonderland and work with Julia Sarr-Jamois?It was in London and the photographer was Michael Hauptman from New York. It was really fun — it was a nice day, it was sunny. There’s one picture
and he was working outside on a house painting it
and we asked him to come to the shoot and we ended up talking a lot
what do you do in your spare time?I do ballet
I go surfing because I live on the Baltic Sea
I started that when I was 9 and I go with my brother and it’s not far away from where I live
Normally I don’t like classical music that much
songs you can dance to.Do you keep a specific diet?My family and me
always — organic foods and a lot of vegetables
And I think it’s important to drink a lot of water
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Michael Heesch grew up in suburban Chicago and dreamed of one day pitching at Wrigley Field
when the University of South Carolina Beaufort left-hander was invited to participate in a pre-draft workout for the Chicago Cubs last weekend
Now Heesch begins the quest of making the dream come again
as the Cubs selected him in the eighth round of the Major League Baseball First-Year Player Draft on Tuesday
Heesch tried to keep his mind off the draft as much as possible Tuesday
but knowing the Cubs had every intention of selecting him
he couldn't pull himself away from the MLB.com coverage for long
"I knew the Cubs were going to try to take me
I was waiting for their phone call," Heesch said
When the call came - a bit earlier than expected - Heesch left the room to take it
saw his son's name flash across the screen
Heesch was on his way to Wrigley Field to meet with representatives from the organization
including president of baseball operations Theo Epstein
for a physical and extended spring training in a week
but it's the first draft for Theo Epstein with the Cubs," Heesch said
"It's an unbelievable privilege to be drafted and to be thought of so highly by the guy who broke the curse of the Bambino."
The news that he will get the chance to pitch at the next level - and for his favorite team
no less - comes on the heels of a remarkable senior season at USCB
Heesch went 9-3 with a 2.21 ERA and a school-record 118 strikeouts to earn Sun Conference Pitcher of the Year honors and help the Sand Sharks win a school-record 41 games and advance to the Avista-NAIA World Series for the first time
In two seasons after transferring from Illinois-Chicago
Heesch compiled a 14-8 record and a 2.81 ERA in 34 games (30 starts)
He struck out 196 and walked 34 in 198 2/3 innings
he was named a second-team NAIA All-American - the first USCB player to earn All-America status - and on Tuesday
All that good news didn't happen by accident
"He's as hard of a worker as I've been around," said USCB coach Bryan Lewallyn
is the Cubs' minor league pitching coordinator
and he's done everything that was asked of him and more
He has turned himself into the guy that he is."
The guy he has become is an intimidating lefty - he stands at 6-foot-5 and 250 pounds - with a fastball that sits around 90 mph and gets to 93 or 94 when needed
an effective slider and a developing changeup
as evidenced by his 9-to-1 strikeout-to-walk ratio this season
and he was durable enough to pitch 122 1/3 innings this year with five complete games
That endurance indicates Heesch could project as a starter
especially if he can develop better command of his changeup
"The other thing he has going for him is he doesn't think he has to throw 95 or 96 to get people out," Lewallyn said
"He has a good feel for pitching and holding runners and that sort of thing
and he understands that he can pitch at 88 to 90 and get guys out
and then when he needs to he can run one up to 93 or 94."
Heesch is the second USCB player to be drafted
Price was selected by the Arizona Diamondbacks in the 30th round of last year's draft
He went 3-2 with a 4.96 ERA in 15 games (11 starts) for the Missoula Osprey in rookie ball last season and is currently in extended spring training at the Diamondbacks' training facility in Scottsdale
Jeff and Kelly Heesch of Watertown announce the engagement of their son
Steven Charles Heesch to Averi Louise Schmidt
daughter of Dan and Michelle Schmidt of Bismarck
The bride-to-be graduated from Bismarck High School and N.D
State University/Valley City State University
She is employed with Bismarck Public Schools
Her fiancé graduated from Watertown High School and S.D
5 wedding in the Legacy United Methodist Church at Bismarck
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iForward high school junior Reni Van Heesch was disappointed she and her peers never got to give their school presentation about Black historical figures and ways to celebrate the month
and Van Heesch joined other students whose efforts to honor the month were resisted by administrators and public officials in Wisconsin
“We spent the whole week trying to get it ready,” Van Heesch
As student council president, Van Heesch and other student council members wanted to give a 10-minute virtual presentation to high school homerooms using Google Classroom.
iForward is a growing virtual charter school that’s part of the Grantsburg School District but serves students across the state. Last school year, there were 695 students enrolled in grades 6-12. In October, the school expanded to include kindergarten through 5th grade
said in an interview that she wanted the student council to focus on planning more social activities like virtual game nights and movie nights.
what about doing something about Black History Month,’ I said
‘Black History Month is very important
but we have an African American history class and we have it infused in our curriculum
My concern is we really need you to do that important job of having events planned that bring kids together and promote friendships,’” Quade said.
Quade also contended there would be an equity issue if the school allowed for a program about Black History Month while not doing anything special for months that celebrate other ethnicities and communities.
don’t have space in their schedules for the optional African American history class
She thought the presentation would be a helpful supplement.
can’t we do a presentation on it?” Van Heesch said.
Other students around the country who pushed for recognition this February also faced opposition. Such incidents come up annually, said Jalaya Liles Dunn, director of the Southern Poverty Law Center's Learning for Justice project that provides resources for educators
unfortunately," Liles Dunn said. "It is arising and coming up more and more
particularly in February but throughout the year."
Just in the Milwaukee metropolitan area, a resolution drafted by five high school students to recognize the month was blocked by the Common Council, which instead passed a more “positive” proclamation written by the mayor.
In New Berlin, where students and parents signed a petition asking for more curriculum on Black history, a school board member said he disagreed with the concept of Black History Month.
Liles Dunn said the rise of the Black Lives Matter movement and recent protests around the country have activated more students
who have turned the racial justice lens on their own schools.
"Young people had a chance to see a modern movement and it reminded them they have power and they can use it," Liles Dunn said
"I’m proud of the young people for standing up for themselves and using their voice
but I’m also disappointed sometimes in the schools."
The presentation also included suggestions for celebrating the month
such as reading a book by a Black author or registering to vote.
youth organizer for the ACLU of Wisconsin who reviewed the students’ draft slides at the request of the Milwaukee Journal Sentinel
said the presentation would have been a fruitful learning opportunity.
"A student-led assembly addressing a real-world issue is a powerful authentic learning opportunity
something that schools implementing best practice ought to encourage rather than shut down,” Owens-Wilson said.
Contact Rory Linnane at rory.linnane@jrn.com. Follow her on Twitter at @RoryLinnane.
Esther who is represented by Next Models wears for the cover top and trousers 3.1 Phillip Lim
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Our cover star ESTHER HEESCH sits down with Editor ANA MARKOVIC to talk about getting scouted at 15
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Just a few days ago I rewatched the „Dior and I“ movie with my family and it brought back all the beautiful memories
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WAUKESHA - Angie Van Heesch has never met Griselle Cruz face to face
When Van Heesch learned that Cruz had been stabbed
Van Heesch thought about the Waukesha woman's three children for who Van Heesch's 17-year-old daughter babysits on Sundays
She also thought about her own children and the trauma they have faced in their own lives
So it was an easy decision to set up a recovery and support fund for Cruz
whose injuries were significant after she was stabbed in the back outside her home in front of friends and family
Heartened to hear that the Cruz children's school was helping any way it could
she "wanted to build on that," which is what The Cruz Benefit Fund at Waukesha State Bank will try to do
it was about helping a mom and her family," Van Heesch said
"My children all have been in foster care and have had traumatic life experiences
The fund is intended to assist the family with medical and general living expenses while Cruz focuses on her recovery
Angie's daughter Kadejah knows the children well
Even the babysitting arrangement was a way for Angie's family to help alleviate the rigors experienced by another young family
"She babysits most Sundays for a few hours so Griselle can go to church and then rest for a few hours," Van Heesch said
noting that Cruz had been working a third-shift job
The shock of what occurred — with police and rescue workers arriving to find a 9-inch kitchen knife sticking out of Cruz's back as she lay face down on a neighbor's lawn — was almost too horrid to imagine
"There really are no words to explain how to feel about this situation," Van Heesch said
It would be an ideal Saturday that turned disastrous
My heart breaks for all the witnesses that are processing this traumatic experience."
Griselle is active in the community and was a leader for the Blair School PTO
faces one count of first-degree attempted homicide
domestic abuse and use of a dangerous weapon
carrying a maximum sentence of 65 years in prison
according to a criminal complaint filed May 7 in Waukesha County Circuit Court
Van Heesch can only hope the family can pull together
"I hope that Griselle and her family will be able to move on from this and build an even stronger
A way to helpDonations for Griselle Cruz and family can be dropped off at any Waukesha State Bank location or mailed using this address:
whistleblower will receive $4.41 million from settlement
.st1{fill-rule:evenodd;clip-rule:evenodd;fill:#2a2a2a}By Brendan KirbyMOBILE, Alabama – Infirmary Health and three other defendants have agreed to pay $24.5 million to settle a federal fraud lawsuit, and a doctor who blew the whistle will reap millions
according to a settlement announced Monday
Attorneys indicated they would file the settlement paperwork by Saturday. The Justice Department outlined terms of the agreement in a news release. The federal government picked up the lawsuit from Dr
who had filed a whistleblower lawsuit alleging that the company was improperly paying incentives to induce doctors to order tests reimbursed by Medicare and other federal health programs
"Financial arrangements that compensate physicians for referrals encourage physicians to make decisions based on financial gain rather than patients' needs," Assistant Attorney General Stuart Delery said in a prepared statement
"The Department of Justice is committed to preventing illegal financial relationships that undermine the integrity of our public health programs."
The agreement settles claims against Infirmary Health
a pair of affiliated clinics and Diagnostic Physicians Group
Infirmary Health CEO Mark Nix noted that the company
the largest private health care provider in Southwest Alabama
admitted no wrongdoing as part of the settlement
He added that patient care never was an issue
nurses and employees work to provide the highest quality of care to the 800,000 patients we treat each year," he said in a statement
"This agreement to settle these claims represents our strong desire to move past litigation about what has been a very complex issue and allow us to end this distraction so that we can focus on our mission and purpose as a community healthcare provider."
Nix noted that claims made by the government and Heesch against Infirmary Health and Infirmary Medical Clinics had been dismissed earlier this year
The settlement resolves claims against the affiliates and removes the possibility that the government could appeal the judge's earlier dismissal
"This settlement will allow us to avoid additional expenses of defense and the distractions associated with litigation," Nix said in the statement
"Our intent has always been to comply with the very complex and extremely technical Stark Law
This complaint resulted from what has been a disagreement with the government over our interpretation of the law as written."
formally called the Physician Self-Referral Act
places limits on referrals of Medicaid and Medicare patients
It is intended to ensure that a doctor's medical judgment is not tainted by improper financial incentives
The government's civil complaint alleged that the two Infirmary Health-affiliated clinics
IMC-Diagnostic and Medical Clinic in Mobile
had agreements with Diagnostic Physicians Group to pay doctors a percentage of Medicare payments for tests and procedures referred by the group's doctors
Authorities contended that amounted to a violation of the Stark Law and the Anti-Kickback Statute
Also named in the lawsuit was Infirmary Medical Clinics
an affiliate of Infirmary Health that directly owns and operates the two clinics named in the suit and about 28 other practices in the Mobile area
Infirmary Medical Clinics purchased Diagnostic and Medical Clinic from Diagnostic Physicians Group in 1988 and agreed to pay the group a share of the revenues the clinics collected
including Medicare payment from diagnostic imaging and laboratory tests
After Infirmary Medical Clinics acquired the IMC-Northside Clinic in 2008
the physicians practicing there joined Diagnostic Physicians Group and agreed to the same key terms as the earlier agreement with Diagnostic and Medical Clinic
The government alleged that these payments were illegal kickbacks and that in June 2010
an attorney for Diagnostic Physicians Group warned employees of both medical practices that the compensation likely violated the law
The allegations first came to light in a lawsuit filed by Heesch
a cardiologist who had been employed by Diagnostic Physicians Group
Heesch sued under a provision of the False Claims Act that allows private citizens to act on behalf of the government and share in recovery
Heesch's complaint described a complicated financial relationship between the doctors and Infirmary Health
It listed $521.6 million in payments from government health insurance programs from 2004 through 2010 to affiliated doctors
The suit also alleged that doctors' pay was tied to referrals and that they received more than $18.6 million in bonuses during the time period
The Justice Department said Monday that Heesch will receive $4.41 million as part of the settlement
"Today's settlement represents a single but significant step towards achieving integrity in the administration of public health programs in this region," Mobile-based U.S
Attorney Kenyen Brown said in a prepared statement
physician groups and other medical entities operating illegally within public health programs will be held accountable
who helped bring this particular case to light."
The defendants agreed to sign a "corporate integrity agreement" as part of the settlement
The agreement with the inspector general of the U.S
Department of Health and Human Services requires the defendants to enact internal compliance reforms and submit federal health care program claims for independent review for the next five years
"Patients must know that medical advice is based on best practices
not on their provider's bottom line," Office of Inspector General Special Agent in Charge Derrick L
"We are pleased these allegations are resolved and will continue to work with the U.S
Department of Justice to investigate and pursue illegal
the government has recovered more than $20.2 billion through False Claims Act cases since January 2009
with more than $14 billion of that amount coming in cases involving fraud against federal health care programs
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