Photo: Marcel van Hoorn.Russian turkey meat exports are on the rise driven by soaring sales to China where it proved to be highly competitive are projected to reach 35,000 tonnes in 2025 and 60,000 tonnes in 2030 executive director of the National Association of Turkey Producers revealed during an industry conference in Moscow Around 60% of Russian turkey is exported to China where Russian firms managed to eat into the market share of the other prominent suppliers “we have ousted large suppliers from this market: the US and South America.” ALSO READ: Bird flu outbreaks in Europe disrupt Russian hatching egg imports Exports are expected to remain a key force driving the Russian turkey industry growth Russian farmers manufactured 438,000 tonnes of turkey which was 3.8% up compared with the previous year the output is expected to climb further by 6% to 465,000 tonnes The ultimate goal is to push the export share to 10% of the turkey meat production A worsening bird flu situation and a decline in consumption in key sales markets are the main challenges the Russian turkey industry faces we also see risks associated with a decrease in overall meat consumption Europe is already seeing the negative dynamics of the consumption of all types of meat meat often becomes less affordable for consumers,” Velmatov said The impact of the ESG agenda and tightening environmental regulations on turkey farmers is also seen as a threat to the industry ALSO READ: Eastern Europe weights in on plans of egg exports to the US the Russian turkey industry could have experienced a stronger growth in output but the bird flu epidemic hurt hatching egg imports and consecutively hampered the industry’s production performance “We mainly imported them [hatching eggs] from Europe By the end of 2024 we manufactured 66% of the products in our country where the total market demand is estimated at 52 million eggs,” Velmatov said Velmatov projected an increase in the production of hatching eggs to 38 million pieces while the demand in this segment will jump to 55-56 million pieces Several new projects currently under discussion can boost Russian hatching egg production further by 30-40% in the coming years Please note that this is an automated translation and it will not be perfect All articles have been written in English and if anything appears to not make sense A new type of training camp: intervals around New Zealand on a fully-loaded bike but after 12 years of sharing so much of our lives—living and spending most of our time together— it feels necessary to create space between us to both reconnect with ourselves and fully embrace our individual expression.” Jazz Monroe called it “a revelatory experience that requires no legible revelations: vocals of ecstatic defiance matched to music seemingly composed of pure magnitude; melancholic synths and bombastic strings and drums.” He continued against-the-odds triumph against staggering forces.” You currently use an outdated internet browser. You can upgrade to a modern browser or use the Google Chrome Frame to optimize your viewing experience We’re proud to share that ARVOO Imaging Products is the chosen supplier of Hoorn’s newest scan vehicle This state-of-the-art ANPR vehicle is already hard at work ensuring efficient parking enforcement of both paid parking zones and permit areas across the city Thank you to Gemeente Hoorn and Brickyard for the seamless implementation this summer a special thanks goes to Chantal van der Wolk-Robert and Lucas Van Mouwerik We look forward to seeing the continued positive impact the ScanGenius scan system will have in Gemeente Hoorn ARVOO was founded in 1993 as an engineering firm specializing in automatic image and signal processing by computers including the integration of artificial intelligence This thirty years of experience and passion for image processing technology make ARVOO a unique company within the industry ARVOO has a team of innovative hardware and software developers who continuously collaborate on new applications and products Market demand guides their development efforts ensuring that the team aligns with the needs of the market Since ARVOO develops both the hardware and software in-house enabling rapid response to customer preferences and requirements Taco van der Hoorn’s Cube Litening Aero C:68X must be the most custom bike of the 2025 men's Paris-Roubaix.  The Cube Litening Aero C:68X is the aero bike used by the Intermarché–Wanty WorldTour team.  the mechanics have been tinkering with van der Hoorn's race bike which we were able to take a good look at before the race got underway in Compiègne.  Ellery James Roberts and Ebony Hoorn have released three studio albums as a duo BY Megan LaPierrePublished Feb 24 "We can never know where life will lead us, but for the foreseeable future we won't be collaborating together anymore as Lost Under Heaven," Roberts and Hoorn wrote in a statement posted to social media today. "Only love remains between us, but after 12 years of sharing so much of our lives — living, working, and spending most of our time together — it feels necessary to create space between us to both reconnect with ourselves and fully embrace our individual expression." See Roberts and Hoorn's full statement below. View this post on Instagram A post shared by LOST UNDER HEAVEN (@lostunderheaven) Be the first to get our biggest stories delivered to your inbox. The momentum Howell gained from nearly erasing a nine-run deficit against Brighton Monday seemed to carry over into the rematch between the rival baseball teams Thursday Howell rolled to a 14-3 victory over Brighton in a game that ended after five innings because of the 10-run mercy rule The Highlanders built their 14-3 lead through three innings Brighton jumped out to a 9-0 lead after three innings before Howell scored seven unanswered runs over the next three innings The Highlanders had the tying run at the plate in the sixth before Josh Metz got the final four outs for the save Nick Hoorn and JT Thomas hit home runs to power the Highlanders’ attack Josh Soneral and Jimmy Steakley each drove in two runs for Howell (2-2) RELATED: Knee injury added to stress of college recruiting for Howell softball star Addison Caldwell RELATED: Brighton's Sam Meriweather runs near-record in race that isn't his main event Hayden Beaver was 4-for-4 with four runs and two RBIs Jacob Monroe drove in four runs and Nolan Carruthers drove in three runs for Pinckney (3-1) in the second game Owen Zylka struck out seven batters in 4 2/3 innings and had two RBIs Lucas Frack drove in three runs and Bobby Griffon was 2-for-2 with two RBIs for Hartland (1-0) The Sentinels didn’t allow a hit in 11 innings to sweep Stockbridge Noah Piesko threw no-hitter and fanned 13 batters in seven innings in the first game Mickey Brown had eight strikeouts in three innings and Ryan Eikey pitched the final inning to combine for a no-hitter in the nightcap Drew Goodwin drove in three runs in the second game Addie Frantti had two goals and one assist as Hartland ended a two-game losing streak by winning its KLAA West opener “We had a couple of games where we lost to a couple of very good teams,” Hartland coach Andrew Kartsounes said “I thought our last game we weren’t connecting as well and being creative together I thought we played well as a team today and really moved in a positive direction.” Brighton is off to its first 3-0 start since 2019 ending a four-game winless streak (0-2-2) in its rivalry with Canton Brynn Bobby and Kyla Bobby scored for the Bulldogs Olivia Sebestyen and Brynn Bobby scored for Brighton which got a shared shutout from Macy Martin and Anna Brown-Nall on Tuesday Hartland’s only victories in individual events were by Roman Ignagni in shot put (45 feet Raymond Schleif in discus (131-2) and Chris Collins in high jump (5-3) Hartland freshman Hannah DePestel made her high school debut by winning the 400 in 59.26 seconds and the 200 in 27.39 She was also on a first-place 3,200 relay team Elliana Neuer won the 1,600 in 5:24.24 and was on two winning relays for Hartland while Loren Deslieres and Caden Friemark had four each Mia Balogh three goals and Maggie Burchfield two goals and three assists for Brighton (2-0) Ava Deyo had three goals and Janie Mitter two for Howell Taco van der Hoorn suffered a career-threatening crash in April 2023 – but after months of hard times Dutchman beats Krijnsen and Laporte to take first win after long-term concussion layoff Taco van der Hoorn (Intermarché-Wanty) won the Elftedenrace scoring his first victory since 2022 just two months after returning to racing following a 16-month spell on the sidelines with concussion The Dutchman was in the break for much of the 200km race and won with an attack from the lead group at 3.6km from the finish line. Seven seconds behind Van der Hoorn, Jelte Krijnsen (Parkhotel Valkenburg) and Christophe Laporte (Visma-Lease A Bike) rounded out the podium having also been in the 17-rider breakaway move Results powered by FirstCycling Dani has reported from the world's top races She has interviewed many of the sport's biggest stars and her favourite races are the Giro d'Italia Dutch rider back to health after severe concussion layoff Intermarché-Wanty announced a two-year extension with popular Dutch rider Taco van der Hoorn on Wednesday winner of a stage in the Giro d'Italia and one-day races such as Omloop van het Houtland and the Brussels Cycling Classic The team's Performance Manager Aike Visbeek said the group missed him during his extended absence "Taco van der Hoorn is one of our most popular personalities a rider who is admired by the fans for his aggressive racing style," Visbeek said he forms the core of the team on which we build our identity since our accession to the World Tour in 2021 he inspires his teammates with his temperament and good mood which is why we missed him so much during his long absence he was immediately ready to perform and managed to maintain this level until the end of the season We are very happy to be able to count on him again in the coming seasons Van der Hoorn was a relative latecomer to the WorldTour signing with Jumbo-Visma in 2019 at the age of 25 following a successful season with Roompot that included a stage win in the BinckBank Tour He joined Intermarché in 2021 and racked up three wins that year including his Giro d'Italia stage win where he held off the chasing peloton by a mere four seconds after being in the breakaway from kilometre zero Van der Hoorn came within millimetres of a Tour de France stage win in 2022 being narrowly out-paced by Simon Clarke from a five-man escape He looked set for another shot at a victory in the Grand Tours in 2023 until his crash in the Tour of Flanders left him with a serious concussion Van der Hoorn said he has confidence in the future "It is difficult to summarize all the progress made over the past eighteen months but I hope that my experience can serve as an example for anyone going through a dark period," the affable Dutch rider said "I've chosen to continue my career with Intermarché-Wanty "My personal ambition fits perfectly with the team's objectives I enjoy the full confidence of the sports directors in the races in which I believe I have a good chance of achieving a good performance I feel involved with it and I feel listened to in the development of our equipment I share the same vision as our Head of Equipment Mikey van Kruiningen always seeking to push the limits together with our technical partners." she coordinates coverage for North American events and global news As former elite-level road racer who dabbled in cyclo-cross and track Laura has a passion for all three disciplines When not working she likes to go camping and explore lesser traveled roads UCI governance and performing data analysis The Hoorn police are investigating several tips in their search for the man who raped a 31-year-old Polish woman early this month. He attacked her in broad daylight in a park between Schout in Hoorn and Dorpsstraat in Zwaag The man approached the woman while she was walking in the park at around 5:00 p.m He pulled her into the bushes and raped her Witnesses saw the man and the victim emerge from the bushes at the same The police did a forensic investigation at the scene and officers went into the neighborhood to talk to locals and seek witnesses the police said they’d received multiple tips “Our detectives are still following up on them,” a police spokesperson told NH Nieuws “That this could happen in the middle of the day is incomprehensible Primary and secondary schools in and around Hoorn said on Friday that children are being added to a group on Snapchat Schools in the Noord-Holland city confirmed that they issued a warning to parents and children about the matter Tabor College and the small vocational school Vonk both warned parents about the chat group “dit wordt de grootste groeps-chat ooit,” which translates in English as “this will be the biggest group chat ever.” Primary schools have also spoken to children about it They advised the children to leave the group immediately and to talk to their parents or guardians about it It is not yet known how many children have actually been added to the group It is also not known whether they were shown pornographic imagery showing adults or images portraying sexually abused children It has not been made clear whether those added to the group were also encouraged to share explicit photos and videos of themselves or named as the administrator behind the chat group It has yet to emerge whether similar warning have been issued outside of Hoorn and the surrounding area In January, Giro d’Italia 2021 stage winner Taco van der Hoorn rejoined his Intermarché-Wanty teammates for the first time since his crash during a Spanish training camp Although at that time he had not fully regained his strength and struggled with intense group rides and attend the team’s official presentation “I was very happy to join the team for the first time since my crash to be united with staff and riders all together in their preparation for the 2024 season which unfortunately started without me because of the consequences of my concussion The past couple of months I alternated between hope and doubt with periods of rapid progress as well as weeks during which I suffered and was forced to rest,” he said at the time he has ramped up his training and has been cleared to race After 16 months of recovery from concussion Taco van der Hoorn is ready to race again in Tour of Leuven on 15 August Show him some love ❤️ pic.twitter.com/wJioVF48E6 — Intermarché-Wanty (@IntermarcheW) August 13, 2024 He will join his team at the Tour de Leuven – Memorial Jef Scherens on Thursday The 57th edition of the one-day race is 192.4 km a Belgian pro cyclist known for his sprinting prowess and success in one-day races during the 1950s and early 1960s He won the Tour of Flanders in 1956 and also triumphed in Paris-Roubaix and the Belgian National Road Championships Get the digital edition of Canadian Cycling Magazine Δdocument.getElementById( "ak_js_1" ).setAttribute( "value" the horse Shanna Baars rode on the Dutch team at the 2020 European Junior Riders Championships He will continue his sport career under Aniek Hoorn Fernando is a 14-year old KWPN gelding by Westpoint out of Lotus (by Donnerhall x Roemer) Fernando is out of the same dam line as Dutch Olympic team horse Nadine through his grand dam Charites He is a half brother to Katie Robicheaux' small tour horse Galandro (by Bon Bravour) the bay was competed up to ZZ-level between 2016 and 2019 Ottevanger trains at Dressage Stable van Baalen Fernando sold to the Baars family in 2020 as a junior horse for Shanna The pair qualified on the Dutch team for the 2020 European Junior Riders Championships in Pilisjaszfalu where they won team bronze and placed 25th in the individual test Baars continued with Fernando at Young Riders level in 2021 through 2023 showing him at 6 CDi's in three years time: Opglabbeek and Exloo in 2021 Opglabbeek and Exloo in 2022 and Geesteren in 2023 In that period Baars rode on the Dutch Young Riders team with her number one With Shanna now studying law at university and training Farzana G to  Grand Prix level a new rider and owner was sought for Fernando "We're training hard to make the transition to Under 25 but are giving Farzana all the time she needs to master the movements," Baars told Eurodressage "Because I'm still studying we sold Fernando because it's too much otherwise." The bay has been sold to Aniek Hoorn as a schoolmaster Hoorn competed with Ico vd Beekerheide in pony classes at national level in The Netherlands from 2021 through 2023 Last year she rode her first tests on horse TOP's Go for it (by Jazz x Negro) Stalls for Rent at Durondeau Dressage in Peer, Belgium Exceptionally Well Located Equestrian Facility in Wellington, Florida Well-built Equestrian Estate With Multiple Business Opportunities in Sweden Stable Units for Rent at Lotje Schoots' Equestrian Center in Houten (NED) For Rent: Several Apartments and Stable Wing at High-End Equestrian Facility Stable Wing Available at Reiterhof Wensing on Dutch/German border Real Estate: Well-Appointed Country House with Extensive Equestrian Facility in the U.K. Rémi Blot The Dutchman has been an integral part of Potter’s plans this season and is the only player to start every Championship game this term for the Swans The 26-year-old was appointed as vice-captain during the summer and has regularly led the side as skipper Leroy Fer has faced injury problems Van der Hoorn’s current contract is due to expire next summer but while not prepared to discuss specific details Potter says discussions to keep the ex-Ajax centre-half in SA1 are in progress “There is no update as such but we are speaking to the player,” said Potter “I would prefer to keep the conversations between the player and the club private he has got better and better and has been playing to a really consistent level “He has the potential to continue to improve and I am sure he will see himself being able to play higher and that is really good.” Van der Hoorn had to wait for his chance for regular first-team football after joining Swansea in the summer of 2016 And Potter feels there is plenty more to come from a player who has performed so consistently “He is at a good age where he has some good experiences beyond him but still has a lot of his career ahead of him," he added he can be a bit of a grumpy so and so at times “He has responded to the leadership role he has had in the group and we look forward to him carrying on that development.” © 2025 Swansea City Association Football Club Limited In the wake of the exhibition of his decade long project “Urban Songlines” on view at the Tate I sat down with Dutch artist Allard van Hoorn for a conversation about art and its relationship to public space By designing collaborative participatory choreographies for architecture Allard van Hoorn encourages us to find novel ways of connecting experiencing and listening to public spaces David Van Leeuwen: How did you come to be interested in public space and the relationship of art to public space Allard van Hoorn: I guess I wasn’t always an artist in my youth I followed a path dictated by my environment at one point I felt like I wanted to develop a personal relationship to the world I felt that the point to start is public space because that is where I had to learn I had to step out of my door and feel and see and look at the world in order to be able to relate to it my idea was to investigate public space by doing some interventions in them.  I remember the very first thing I brought from Holland was a roll of duct tape and that coincided with the date I moved to Barcelona There was a free market in the streets of Amsterdam and kids and grownups tape a few square feet in the sidewalk before Queen’s day and they occupied that space with the tape so I found one in an old factory and the studios were only divided by the beams in the ceiling I was in the space for a while I was thinking about how to relate to the studio but at that point I had no idea what to do with the studio I eventually decided to reproduce what I saw last I taped the circumference of that square space that was mine I would put the cross in it as people in Amsterdam would do for Queens’ day I put the words on the wall that people put in it saying ‘occupied’ I left for a week and came back to the space the neighbor on the right-hand side had pushed an empty shopping cart containing a blank white canvas into the space and it was sitting squarely in the space a starting point.  The neighbor on the other side had drawn on the wall with an arrow pointing at my space ‘sin trabajo’ which translates in Spanish into ‘without work,’ the literal translation is jobless “hey if you don’t do anything with this space you may end up unemployed.” I thought it was amazing that just me doing a contemplative passive exercise with this space for myself as a thinking exercise led to two strong reactions from my neighbors I started to do interventions in the streets I wanted to see what possibilities would open up if we listened to spaces like buildings and bridges instead of just inhabiting them It is baked into our memories and it largely guides our attention How is sound important to your work and to public space I got very interested in the idea of how to work with public space and sound after reading “Songlines” a book by Bruce Chatwin in 2008 I was struck by the technique of aboriginals to translate their public space by singing the shape in language and in tone it was a threefold method in relating to the land it is a sonic map that you get to learn when you are born when the aboriginal mother is pregnant and she feels the first kick she marks the ground and the tribal elders assign a stretch of land from that point on to the horizon that is the songline that they learn to sing – the songline passes throughout the entire continent The tonal structure of the sung description of this landscape allows them to envision how the landscape will look like without knowing the language they relate to the land in a spiritual way And the third is a sense of management and taking care of the land to maintain balance I learned that I was super interested in sound being a representation of public space More than half of the people I know live in cities but active listening can open up new avenues of understanding places 063 Urban Songline (Another Hurling of the Silver Ball) | Latitude: 50.204794° N – 50.214926° N / Longitude: -5.482636° W – -5.493938° W Ives Feast Day tradition of ‘hurling’ a small silver ball is chased through the town as part of the celebrations You have re-imagined the small silver ball into a larger one that is a mirror of sorts I have always liked the idea of the artist putting up their mirror to the world I learned that it was previously an active fishing and mining town and that there was a close-knit community that was more and more broken up by recent tourism These cute houses are rented out as holiday homes to tourists whose presence has gentrified the area pushing older communities into the suburbs helping each other out seem to have been lost to a certain extent the idea of supersizing the silver ball felt like a tool for self-reflection in relation to the sense of community gentrification; the slow-moving very reflective ball became a rolling mirror through public space that allowed participants to see each other together in the landscape What kind of choreographies would they design How would they reimagine the function of the silver ball if they had control over it We organized workshops with the different communities and any other community that wanted to collaborate We invited them to design their own workshops together with me and the Tate team and to see how they wanted to use that reflection that mirror that rolls through public space as a way to reconnect and discuss the idea of community sense in their town Guy Debord speaks of the re-humanizing effects of participation How do you view the value of participation by the audience and collaborators in your works generally participation and collaboration is something that develops while you are doing the project and its kind of a feedback system Buckminster Fuller had this design science implementation model where feedback is essential Continuous feedback loop into the original system and the more we get to the day we all perform together and activate this thing in public space something changes because somebody gave this very insightful input into the system I think it is essential that the spirit of the project has a life after the artist came and activated it in a certain community I try to create projects where the local community has as much ownership as possible if not entirely Their participation is the activation of the artwork Upon watching the video of the performance it is clear that there was a large turnout from the St What was it about the project that resonated with them The feedback I got was that people had a lot of ownership over the project They came up with the choreography for their own parts they have a ritual where they beat the grounds with a stick to wake up the apple trees that takes place in the community orchard in February the event is meant to stimulate a good harvest It was their idea to beat the silver ball as a community tool to wake it up and wake up its senses As the apple-orchard group handed over the ball to the skate park community meeting each other talking with each other in that landscape in the reflection of the ball that allowed a wider conversation Are there artists or thinkers that have influenced your ideas about art and its relation to public space or the value of public spaces in general I already mentioned Richard Buckminster Fuller I see his creativity and his discovery and research into the relationship of man in the special and mechanical world was an exercise that ended up in useable and tangible objects such as architecture and vehicles What I learned from this practical approach to art is that we can create tools that function in communities to spark conversation or incite change that have done projects that don’t seem like art performances because they are placed out of that context yet again in the public spaces where you don’t expect them to be art For artists working with interventions in public space this also goes for Christo and Jeanne Claude is that the audience extends beyond an art audience When you are in a white cube or in a museum When you encounter something in public space and you do not have to know anything about art and when you can interact with it differently I am interested in art and artists who allow meaning to be created by their audience or users; the openness that void where you have the chance to put in your own meaning A renowned architect once said that what would define the greatest architects How do your ideas of space relate an architect’s idea of space Architecture has to be more than the function alone The form must invite certain other aspects that are common to our lives and that is why I often introduce dance in buildings because I see dance as somewhat of a polar opposite to architecture which is regarded as one of the highest physical technological achievements of society Where architecture is static and rigid in its power If the body moves in public space it choreographs the space self-controlled piece of architecture in public space Then these two are opposites on the spectrum To create architecture came from the body and walking “Walkscapes” by Francesco Careri the very first architectural interventions in public were common paths between groups in the landscape creating a line in public space and together with dance they were the first two ways of creating architecture in space “Urban Songlines 2009-19” was on view at Tate, St. Ives May 24-September 1, 2019. Allard van Hoorn was featured in Fridman Gallery’s New Ear Festival 2020.   Will Benny Or Innovate Environmental Design in the Art World? Israeli-born Sculptor Sheds Light on Mexican-American Border Crisis in New Exhibit  David Van Leeuwen is a writer and attorney living in Brooklyn He has written on a wide range of topics for art David has also for many years collaborated with artists screenshot of Sunrise / Sunset Haiku Engine at sunrise Allard van Hoorn's Sunrise / Sunset Haiku Engine visually and verbally translates the sky above the Whitney Museum Using the names of the Dutch Boy house paint colors as a “haiku engine,” it generates site-specific poetry for day and night a screenshot of a patch of sky above the Whitney is taken from a webcam view of the Manhattan skyline The image is then pixelated to extract a range of colors which are matched to swatches of the Dutch Boy colors whitney.org is tiled with these colored paint swatches and their accompanying labels representing the colors of the sky at that moment The project uses the sky as a free zone of imagination and draws attention to the perception of our environment Visit Allard van Hoorn's website. installation and performance artist creating choreographies and musical scores for architecture scenographies for the built environment and scripts for investigating our relationships to public and architectural spaces His work has been shown at institutions and events including the 7th Bucharest Biennale; 1st Yinchuan Biennale; 6th Marrakech Biennale; 3rd Istanbul Design Biennial; 2nd Tbilisi Triennial; 12th Biennal de la Havana; 2013 Shenzhen / Hong Kong Bi-City Biennale of Urbanism and Architecture; 2011 Gwangju Design Biennial; ISCP Amsterdam; Storefront for Art and Architecture; NYC © 2025 Whitney Museum of American Art A Realistic Day In My Life Living In New York City Swansea City boss Steve Cooper makes six changes for the first game of 2020 against Charlton Athletic Wayne Routledge and Borja Baston are all restored to the starting XI Tom Carroll and Bersant Celina all miss out after starting against Barnsley while Sam Surridge has been recalled from his loan spell by Bournemouth Ben Cabango and Kyle Naughton making up the back four Skipper Matt Grimes partners Byers in midfield with Dhanda taking up the number 10 role as Andre Ayew and Routledge occupy the flanks while the visitors include former Swansea midfielder Darren Pratley in their starting XI Swansea City: Freddie Woodman; Connor Roberts Davide Cimolai won the race for second place just ahead of Peter Sagan, whose Bora-Hansgrohe team had done so much of the work on the front of the peloton, pushing to try to drop rival sprinters but getting their timing wrong when it came to chasing down the break. Read more“I can’t believe it,” Van der Hoorn said “I just wanted to go in the break and be aggressive for the whole Giro I know how difficult it is to try to win a stage or even get to the finish line with the group but if there’s even 0.5% of a chance you just take it.” The Ineos Grenadiers rider Ganna was safely in the peloton to retain the pink jersey the Italian continuing to lead by 16 seconds from Tobias Foss with no major changes at the top of the general classification before the potential for a more serious shake-up on Tuesday Van der Hoorn was the last survivor from a youthful eight-man breakaway which had gone up the road with hardly any hope let alone expectation as the 190km stage from Biella began on damp roads The group included four riders still in their first professional season A lead that reached six-and-a-half minutes was gradually cut down on the leg-draining rolling finish to the stage and it seemed a matter of when they would be caught even when Van der Hoorn raced away from Simon Pellaud to go solo with nine kilometres remaining “I didn’t believe [we had a chance] when it was only one minute with 25km to go but the guy from Androni [Pellaud] was pulling really hard on the last climb,” the Dutchman added and then I heard on the radio the gap was 40 seconds so I just went full gas to the line With one kilometre to go I was looking back and thinking ‘I’m going to make it’ The peloton passing through Campetto Village Photograph: Tim de Waele/Getty ImagesVan der Hoorn joined Intermarche-Wanty-Gobert from Jumbo-Visma in the winter as the Belgian squad stepped up to the WorldTour level In a quote published on his team’s Twitter account Van Der Hoorn said: “Five months ago I considered quitting cycling because I had no contract Attention now turns to Tuesday’s 187km hilly stage from Piacenza to the uphill finish in Sestola where the first major changes to the overall standings since the opening time trial could come 'I'm making progress but it's often three steps forward and then two back' says Dutch rider Taco van der Hoorn has outlined the frustration and long recovery process as he continues his fight back to health from a concussion suffered back in April The Dutchman crashed hard at the Tour of Flanders and hasn't raced since after being hit by a heavy concussion he's still in the rehabilitation process and is still waiting to get back to 100% Speaking to WielerFlits the Intermarché-Circus-Wanty rider said that "things are going OK" but noted that he still has good and bad periods "Things are going OK considering the circumstances but the circumstances are not very good at the moment," he said I'm making progress but it's often three steps forward and then two back." You'd like to ride again and be part of the peloton again Van der Hoorn was one of several Intermarché riders to crash out of the Tour of Flanders on a nightmare race day for the team that also saw leader Biniam Girmay suffer a concussion But while the Eritrean star recovered relatively quickly and got back to racing by the summer Van der Hoorn's battle back to health has been a long and challenging one He told WielerFlits that the uncertainty about the future only adds to the frustration "And it's also that you have a headache every day "It also caused my concussion to bother me in everyday life – that I had to stay at home a lot and couldn't actually do much." no being with people because it was too busy I was also able to do some work on aero testing and material development I was also able to meet up with friends more often Van der Hoorn is a rider who loves getting in a breakaway and going on the attack, having taken the biggest win of his career on stage 3 of the 2021 Giro d'Italia with a late solo move He's still some way away from being able to replicate the exertions of racing "The last thing that is still not going very well is exertion My doctors are confident that this will heal completely again That's because everything else has also fully recovered The uncertainty is not the most fun to have This injury just doesn't allow itself to be predicted That's tricky because – unlike a fracture or something – there is no end date." Van der Hoorn, who previously suffered a concussion in late 2017 that took him out of the bulk of the 2018 season said that he's working with a rehab psychologist as part of his efforts to recover and get back to racing He said that he's confident he'll be able to quickly get back to his racing level once he's able to train normally again "Once my head is good and if I can train for an hour with more intensity then complaint-free training is also close," he said I will be back to my highest level within two months "That also went very well in 2018 and that has given me a lot of peace of mind since then – that after such a long period of inactivity That I would then lose all my training investment Be one of the first to try our new activity feed The Dutchman made headlines with his dramatic breakaway victory but it almost never happened after he came close to retiring last year Throughout the Giro d’Italia, VeloNews will be talking to some of the unsung heroes in the peloton – those riders that battle on each day without the recognition the major GC favorites or sprint stars receive Ask most people who their favorite rider is and they’ll probably say something like Peter Sagan or Miguel Indurain Not Taco van der Hoorn The Dutch rider who stole fans’ hearts with his dramatic against-the-odds win in the first week of the Giro d’Italia used to have a poster of Graeme Obree – a two-time individual pursuit world champion who made his name with his innovative approach to riding and hour record attempts – on his wall Also read: Giro d’Italia unsung heroes: Pieter Serry the farmer’s son “I like that in his time he was maybe not the biggest talent if you compare it with maybe Chris Boardman, but he was a smart rider. He was always developing something, and he was interested in all the details of the aerodynamics,” van der Hoorn told VeloNews. “I think it’s nice he was not doing the things that everybody was doing, and he looked a bit outside the box.” “He looked at how it was possible to progress if that was with aerodynamics, training, food, or something else. It’s nice to look in a different way, and try to make yourself better.” Obree was best known for his successes in hour record, his “Old Faithful” bike made with parts from a washing machine, and his array of creative riding positions – possibly the most well-known of those was his subsequently banned “superman” position. A post shared by Taco van der Hoorn (@tacovanderhoorn) A little bit of the Flying Scotsman can be seen in van der Hoorn’s approach to racing particularly his pursuit of aerodynamic gains Van der Hoorn rides with narrower handlebars than most and ekes out a touch more aero gain by pushing his brake hoods inwards “I don’t really know him so I don’t think I can compare myself to Graeme Obree but we both think that aerodynamics are an important thing,” van der Hoorn said “I started using [the handlebars] already when I was in my first year as an under 23 but after a week it is not strange at all.” Also read: Taco van der Hoorn’s underdog win is what makes cycling great “I’m happy that I’m one of the few using them so I’m happy with other guys to stay with the wider handlebars.” When van der Hoorn unexpectedly won stage 3 of the Giro d’Italia he utilized all of the aero advantages he could harness From wearing a skinsuit and a helmet with taped-up vents Also read: Giro d’Italia unsung heroes: Simon Pellaud the breakaway specialist “Maybe I would have won the stage with less aero handlebars but maybe not “I think it will always help and it gives me the upper hand and if you can save energy for the key points then that it’s really important.” it’s more about training and food and that kind of stuff but it’s a detail that can make a difference.” Van der Hoorn spent four days responding to all the messages he received after taking his stage win The victory was something of an allegory for his career almost succumbing to the pack behind but finally persevering Twice he was nearly forced into retirement His first brush with retirement came in 2017 when a heavy fall during a cyclo-cross race resulted in a concussion that sidelined him for eight months he was again facing a future without racing when his contract at Jumbo-Visma ran out and no new team was forthcoming His career was saved first by the Continental Beat Cycling team and then by Intermarché-Wanty-Gobert The ups and downs were tough for van der Hoorn but what got him through was his love of riding his bike Also read: Giro d’Italia unsung heroes: Antoine Duchesne bouncing back from disappointment “I just really like cycling, that’s the thing. I really like the sport, the training, and being with the team and spending each evening with the other riders,” van der Hoorn told VeloNews. “I like the whole cycling life, trying to be better every day and seeing what kind of details you can invest in to be better again. I really like to try to get the most out of my body and to be the best bike rider I can be.” “I also enjoy being outside with nature and the beautiful environment. If I was a swimmer or something you could also progress and try to be the best you can be, but then you are always in the swimming pool. Training is also seven hours riding your bike in nature.” A post shared by Taco van der Hoorn (@tacovanderhoorn) As much as van der Hoorn enjoys riding his bike outside and focusing his attentions on the minutiae of aerodynamics After completing a degree in Human Movement Science a few years ago He has considered doing a Master’s degree in sport psychology but plans to take a philosophy course later in the year and is reading a book on the subject that his friend gave to him ahead of the Giro d’Italia “I read quite a lot during the altitude camp and that was quite nice to do something outside of training but here you’re so busy focusing on the race that I haven’t had time,” said van der Hoorn “I am looking to do a course so that I can study again It’s just a small course to do something else next to cycling.” “It’s good to sometimes not focus on cycling cycling is good but then it is also maybe a bit too much sometimes It’s nice if you can have your thoughts on something else than only thinking about training What’s it like to be an American cyclist living in France Watch to get professional road cyclist Joe Dombrowski’s view Taco van der Hoorn's highly-optimised Cube Litening C:68X TEIs this the most extreme bike at the Tour Taco van der Hoorn's highly-optimised Cube Litening C:68X TEThe bike that ALMOST helped Taco van der Hoorn to a Tour de France stage win With 18km of cobbled roads borrowed from Paris-Roubaix stage five of the 2022 Tour de France promised fireworks The stage victory went to Simon Clarke of Israel-PremierTech (and chapeau to him) with breakaway specialist and bike-tech fetishist Taco van der Hoorn finishing a narrow second With that in mind, we thought it was as good a time as any to take a look at van der Hoorn highly-optimised bike, an unusually specced Cube Litening C:68X TE As a fan of famous aero-innovator Graeme Obree van der Hoorn is a devout follower of the mantra His position on the bike is one of the most extreme in the WorldTour peloton We measured van der Hoorn’s handlebars at a narrow 38cm at the drops but his hoods are turned in to achieve an effective width of just 30cm at the tip of the brake hoods – perfect for long-distance cruising in the breakaway To further optimise his position, van der Hoorn uses a zero-offset seatpost and a short-nosed road saddle. This places him further forward and higher over the bottom bracket which should help him to get the power out when riding in an aggressive position The Cube Litening C:68X TE (the TE stands for ‘Team Edition’) is one of the best aero road bikes available, and it’s no surprise to see van der Hoorn sticking with this model, rather than switching to the new lightweight Cube Litening we spotted at the Giro d’Italia Though it nominally only has clearance for 28c tyres in practice it can take a bit more than that so it arguably makes it an ideal bike for a flat (We're yet to confirm what size tyres van der Hoorn had fitted for the Tour's cobbles but we'd have expected most teams to run 30c rubber – ed.) And it certainly looks as if van der Hoorn’s Cube has seen its fair share of cobbles tidy and well maintained when we photographed it ahead of the Grand Départ in Copenhagen it also had its fair share of battle scars On top of the aerodynamic riding position and bike van der Hoorn has also optimised his drivetrain on the day before the opening stage of this year’s race it had an enormous set of 56/44t chainrings on it Those are chainrings we’d have previously seen almost exclusively on time trial bikes optimised for flat courses van der Hoorn had an 11-34t cassette – a wide range option which likely helps him stay in that whopping 56t chainring more of the time Given the mostly flat parcours of the Tour to date we’d be surprised if van der Hoorn has strayed from that setup since The explanation for this is likely to be as simple as a limited availability of new parts – even former Tour winner Geraint Thomas is still using the same setup (albeit with less extreme gearing) Leaving no stone unturned, van der Hoorn also has the CeramicSpeed OSPW Aero system – a €739 derailleur cage assembly which is claimed to reduce drivetrain friction and improve a bike’s aerodynamics When we last checked in with van der Hoorn, he was running Continental GP5000TL tubeless tyres on Newmen carbon wheels Since then, though, he and the rest of his team have upgraded to the latest Continental GP5000 S TR tyres It’s a tyre which has already secured back-to-back victories at Paris-Roubaix, a win at the world time trial championships, and, perhaps most importantly of all, a coveted spot at the top of our best road bike tyres round-up The Conti tyres were mounted on Newmen Advanced R.50 Streem carbon wheels Notably, Intermarché Wanty Gobert’s head mechanic, Mikey van Kruinigen, told us the team isn’t using tubeless tyre inserts at this year’s Tour Though they offer a run-flat solution in the event of a puncture, van Kruinigen told us the foam inserts have a tendency to soak up tubeless sealant meaning they needed to add more than would otherwise be required that wasn’t acceptable to the team’s weight-conscious riders One nice detail we spotted was a sticker on each rim which noted how much sealant had been added to the system it’s crucial to check its state periodically in order to maintain its puncture-sealing performance The wheels also had a well-worn set of Shimano RT-MT900 disc brake rotors this is likely a reflection of the ongoing shortage of new bike parts across the industry and it appears even pro teams are having to squeeze every bit of life out of their parts While van der Hoorn was narrowly pipped to the line after a gruelling stage over the Roubaix cobbles the former Giro stage winner clearly has good legs and a bike setup that works for him so we’re looking forward to seeing what else is to come over the next two weeks of the Tour Metrics details Adapted plant pathogens from various microbial kingdoms produce hundreds of unrelated small secreted proteins (SSPs) with elusive roles we used AlphaFold-Multimer (AFM) to screen 1879 SSPs of seven tomato pathogens for interacting with six defence-related hydrolases of tomato This screen of 11,274 protein pairs identified 15 non-annotated SSPs that are predicted to obstruct the active site of chitinases and proteases with an intrinsic fold Four SSPs were experimentally verified to be inhibitors of pathogenesis-related subtilase P69B including extracellular protein-36 (Ecp36) and secreted-into-xylem-15 (Six15) of the fungal pathogens Cladosporium fulvum and Fusarium oxysporum Together with a P69B inhibitor from the bacterial pathogen Xanthomonas perforans and Kazal-like inhibitors of the oomycete pathogen Phytophthora infestans P69B emerges as an effector hub targeted by different microbial kingdoms consistent with a diversification of P69B orthologs and paralogs This study demonstrates the power of artificial intelligence to predict cross-kingdom interactions at the plant-pathogen interface In response to apoplast colonization by bacterial the host plant secretes a broad diversity of metabolites and proteins that are presumably toxic and harmful to extracellular microbes have learned to live in this challenging environment but molecular mechanisms that these pathogens use to avoid or suppress extracellular immunity are largely unknown we demonstrate that AFM can also be used for cross-kingdom discovery screens for protein–protein interactions at the plant pathogen interface illustrated with the discovery of four pathogen-secreted inhibitors targeting a tomato-secreted immune protease P69B facilitating statistical analysis that demonstrates that AFM scores are statistically different between compatible and incompatible complexes (p = 2.1e–09 and 1.8e–9 To analyse the structures of the best models for each of these 376 protein pairs we established a custom script in Python to present the surface of the hydrolase structure in gray with the active site in red and the putative inhibitor as cartoon and lines colored using a rainbow scheme based on the plDDT scores This presentation facilitated a quick classification of how the SSP binds to the hydrolase a The 376 candidate complexes were manually screened for complexes where the SSP blocks the active site of the hydrolase with an intrinsic fold b The remaining 36 candidate complexes included 13 complexes between Kazal-like inhibitors and P69B and cystatin-like inhibitors with Pip1 and 23 candidate complexes with other candidate inhibitors transcriptome analysis of infected plants showed that genes encoding eight SSPs are not expressed at the tested conditions whereas genes encoding 11 SSPs are expressed during infection No transcriptomic datasets were available for Xp (4 SSPs) d Distribution of the final 15 candidate hydrolase-inhibitor complexes over the tested tomato pathogens and target hydrolases The 36 complexes included eight complexes of Kazal-like proteins from Pi bound to P69B, and five complexes of cystatin-like proteins from Pi bound to Pip1 (Fig. 3b) The selection of these inhibitors validated our manual screening method since these interactions could also be predicted by sequence homology No transcripts were detected for eight candidate inhibitors Although the expression of these candidates might have been missed by chosen conditions and materials these eight candidates were not analyzed further There was no expression data available for Xp infections but these four candidates were all retained No novel inhibitors were identified from pathogens Ps and Pi but some inhibitors may not have been included in our SSP selection or have been missed by AFM as false negatives putative chitinase inhibitors are also produced by bacterial pathogens is not in a complex with proteins that have structural similarity to our tomato hydrolase models our 15 SSP-hydrolase complexes uncover candidate targets of these SSPs These data confirm that all four tested candidate inhibitors indeed inhibit P69B so it is likely that XpSsp1 homologs play an active role during Xanthomonas infections although these proteins are highly conserved the residue predicted to occupy the S1 pocket is highly variant (K despite the high structural diversity of the five P69B inhibitors most inhibitors seem to occupy the S4 and S2 pockets with similar residues but the predicted residues occupying the S1 pocket can be strikingly diverse and include both basic (Lys) and acidic (Asp) residues We successfully used AFM as a discovery tool to identify cross-kingdom interactions at the plant-pathogen interface We used AFM to predict complexes between 1879 SSPs with six extracellular hydrolases and from 376 complexes with high scores we manually selected 15 putative inhibitors that block the active site with an intrinsic fold and are likely expressed during infection Four of the candidates were produced and confirmed to be P69B inhibitors This work demonstrates that the use of artificial intelligence to predict cross-kingdom protein complexes can make instrumental contributions to predicting protein functions in host-microbe interactions but these are not in complex with proteins that have structural similarity to the tomato hydrolases these AFM models correctly predicted that four of these SSPs are indeed P69B inhibitors although further assays are required for validation of the predicted structures we successfully used AFM to identify functions of four unrelated We found that the vast majority of the SSPs in AFM-predicted complexes with high scores are probably not hydrolase inhibitors rather be substrates or allosteric regulators which remains to be explored in the future we were successful with identifying inhibitor candidates because we used a stringent selection by manually screening the structures for SSPs that block the active site and have an intrinsic structure This stringent selection resulted in a high hit rate because all four tested candidates were confirmed to be P69B inhibitors In addition to previously described Kazal-like inhibitors of Phytophthora infestans we discovered four P69B inhibitors from three additional tomato pathogens: XpSsp1 from Xanthomonas perforans; CfEcp36 from Cladosporium fulvum and FoTIL and FoSix15 from Fusarium oxysporum These pathogens secrete P69B inhibitors because they are exposed to very high levels of P69B during apoplast colonization This suggests that other tomato pathogens probably also secrete P69B inhibitors that remain to be identified We may have missed some putative P69B inhibitors produced by other pathogens because they were too large (>35 kDa) were not detected in the used transcriptomic dataset It seems likely that other proclaimed chitinases may have antibacterial activities and that this is why they are targeted by bacterial inhibitors It seems likely that P69B has many additional substrates in tomato and its apoplastic pathogens our AFM screen identified 17 pathogen-produced SSPs that interact with the substrate binding groove of P69B but lack an intrinsic structure and might therefore be substrates that can be studied further These ‘ring-of-fire’ positions will likely cause differential sensitivity of the paralogs for the different pathogen-derived inhibitors This variation indicates that the P69B paralogs evolved from parallel arms races with pathogen-secreted inhibitors resulting in gene duplication and diversification in the ancestral Solanum species these observations indicate a fascinating arms race at the plant-pathogen interface These low scores indicate that AFM can produce false negatives Some of the low scores might be due to low mean non-gap MSA depth for some of the SSPs which is below the desired 100 MSA for 45% of the tested SSPs This implies that new interactions might be discovered when additional SSP sequences are added to the database screens for hydrolase inhibitors can be automated using a script that searches for residues of candidate inhibitors that are in close proximity to the active site We propose artificial intelligence to predict plant-pathogen interactions will be a revolutionary approach in future research Mean non-gap amino acid depth for chains of each protein were calculated using the features.pkl output file generated by AFM (Supplementary Data 1 Mean non-gap MSA depths for proteins modeled in several different complexes are the mean of their mean non-gap MSA depths from all complexes Total computing time calculations of AFM were based on the timings.json file of each protein complex To calculate CPU and GPU hours based the timings.json files it is necessary to know that all AlphaFold2 monomer computations were completed with eight CPU cores and one GPU at any time AFM computations were executed with one CPU core and one GPU at any time The proteomes and transcriptomes were from the following genome assemblies: GCF_000007805.1 (P All TM scores were normalized relative to the length of the experimentally resolved proteins Interface residues of experimentally resolved protein complexes were identified using Pymol’s InterfaceResidues script Genes were considered expressed during infection if they exceed an average gene expression ≥2 TPM The minimum expression level of EBI’s gene expression atlas is 0.5 TPM resulting in a binary pJK187 plasmid that contains the 35S promoter and 35S terminator with the nptII kanamycin and LacZ as the fragment to be replaced by insert sequences The gene sequence of P69B (with NtPR1a signal peptide, see Supplementary Table 7) was synthesized at Twist Bioscience and inserted into the binary vector pJK187 using BpiI to yield NtPR1a-P69B-His (pFH20) Plasmids were sequenced using Source Bioscience using 35S promoter (5′-ctatccttcgcaagacccttc-3′) and terminator (5′-ctcaacacatgagcgaaacc-3′) primers to confirm the inserts Validated binary plasmids were transformed into A tumefaciens GV3101 (pMP90) via heat shock transformation The recombinant protein of P69B-His was purified by HisPur™ Ni-NTA resin and concentrated in 25 mM Tris-HCl pH = 6.8 using a 50 kDa MWCO Amicon Ultra-15 filter Sigma-Aldrich) and cultures in LB (Luria-Bertani) liquid medium were induced with 0.1 mM isopropyl β-D-1-thiogalactopyranoside (IPTG) and incubated at 18 °C for 24 h Cells were pelleted by centrifugation at 8000 x g for 5 min and the supernatant was discarded The cell pellet was resuspended in 50 mM Tris-HCl The CelLytic™ Express (Sigma-Aldrich) was used for bacterial cell lysis and the supernatant was collected for further protein purification The recombinant proteins were purified using HisPur™ Ni-NTA resin (Thermo Fisher Scientific) and amylose resin (NEB) and then the TEV protease (Sigma-Aldrich) was added to remove the purification tags His-tagged TEV protease and purification tags were removed over Ni-NTA and a 30 kDa Amicon filter whilst concentrating the cleaved inhibitor protein in 25 mM Tris-HCl pH 6.8 Inhibitors were used immediately or stored at −80 °C The Bio-Rad DC Protein assay kit was used to measure the protein concentration of candidate inhibitors and P69B 85 pmol purified candidate inhibitors were preincubated with 0.85 pmol purified P69B-His protein at room temperature for 0.5 h in 25 mM Tris-HCl (pH 6.8) and then labeled by adding 0.5 μM FP-TAMRA (Thermo-Fisher) and incubating for 1 h at room temperature in the dark The labeling reaction was stopped by adding 4× loading buffer (200 mM Tris-HCl (pH 6.8) 40% glycerol) and boiling for 7 min at 95 °C Samples were separated on 15% SDS-PAGE gel The gel was washed three times with Milli-Q water and scanned for fluorescence with the Typhoon scanner (GE Healthcare) using a Cy3 setting Signal intensities were quantified using ImageJ and normalized to the EpiC1 negative control Statistical testing of inhibition was based on two-sided pairwise comparisons between the putative inhibitor and the EpiC1 negative control Calculated p-values were adjusted for multiple testing using the Benjamini–Hochberg procedure Further information on research design is available in the Nature Portfolio Reporting Summary linked to this article Source data are provided with this paper Apoplastic immunity and its suppression by filamentous plant pathogens Significance of inducible defense-related proteins in infected plants A genomic cluster containing four differentially regulated subtilisin-like processing protease genes is in tomato plants two differentially regulated genes encoding new members of the subtilisin-like proteinase family from tomato plants A Kazal-like extracellular serine protease inhibitor from Phytophthora infestans targets the tomato pathogenesis-related protease P69B A second Kazal-like protease inhibitor from Phytophthora infestans inhibits and interacts with the apoplastic pathogenesis-related protease P69B of tomato A Phytophthora infestans cystatin-like protein targets a novel tomato papain-like apoplastic protease Fungal effector protein AVR2 targets diversifying defense-related Cys proteases of tomato The Cladosporium fulvum virulence protein Avr2 inhibits host proteases required for basal defense Screen of non-annotated small secreted proteins of Pseudomonas syringae reveals a virulence factor that inhibits tomato immune proteases Compatibility in the Ustilago maydis-maize interaction requires inhibition of host cysteine proteases by the fungal effector Pit2 An effector from the Huanglongbing-associated pathogen targets citrus proteases Functional divergence of two secreted immune proteases of tomato Glycosidase and glycan polymorphism control hydrolytic release of immunogenic flagellin peptides Sueldo, D. J. et al. Activity-based proteomics uncovers suppressed hydrolases and a neo-functionalised antibacterial enzyme at the plant-pathogen interface. New Phytol. https://doi.org/10.1111/nph.18857 (2023) Rapid evolution in plant chitinases: molecular targets of selection in plant-pathogen coevolution Selection on Glycine beta-1,3-endoglucanase genes differentially inhibited by a Phytophthora glucanase inhibitor protein Evolution of a guarded decoy protease and its receptor in solanaceous plants Structure of the glucanase inhibitor protein (GIP) family from Phytophthora species suggests coevolution with plant endo-beta-1,3-glucanases Enhanced late blight resistance by engineering an EpiC2B-insensitive immune protease Protein complex prediction with AlphaFold-Multimer Highly accurate protein structure prediction with AlphaFold Computed structures of core eukaryotic protein complexes AlphaFold2-multimer guided high-accuracy prediction of typical and atypical ATG8-binding motifs Predicting the reactivity of proteins from their sequence alone: Kazal family of protein inhibitors of serine proteinases DALI shines a light on remote homologs: one hundred discoveries Structure of the subtilisin Carlsberg-OMTKY3 complex reveals two different ovomucoid conformations TM-align: a protein structure alignment algorithm based on TM-score Crystal structure of tarocystatin-papain complex: implications for the inhibition property of group-2 phytocystatins The mixed xylem sap proteome of Fusarium oxysporum-infected tomato plants The top 10 fungal pathogens in molecular plant pathology Top 10 plant pathogenic bacteria in molecular plant pathology The top 10 oomycete pathogens in molecular plant pathology The complete genome sequence of the Arabidopsis and tomato pathogen Pseudomonas syringae pv Genome sequence of the plant pathogen Ralstonia solanacearum A gapless genome sequence of the fungus Botrytis cinerea Comparative genomics reveals mobile pathogenicity chromosomes in Fusarium A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome Genome sequence and analysis of the Irish potato famine pathogen Phytophthora infestans ApoplastP: prediction of effectors and plant proteins in the apoplast using machine learning Detecting sequence signals in targeting peptides using deep learning SignalP 5.0 improves signal peptide predictions using deep neural networks Identification of several pathogenesis-related proteins in tomato leaves inoculated with Cladosporium fulvum (syn Fulvia fulva) as 1,3-beta-glucanases and chitinases Contrasting roles of the apoplastic aspartyl protease Apoplastic enhanced disease Susceptibility1-Dependent1 and Legume Lectin-like Protein1 in Arabidopsis systemic acquired resistance An extracellular aspartic protease functions in Arabidopsis disease resistance signaling Structural basis for Ca2+-independence and activation by homodimerization of tomato subtilase 3 Binding of chloromethyl ketone substrate analogues to crystalline papain Crystal structure and mode of action of a class V chitinase from Nicotiana tabacum Crystal structure of class III chitinase from pomegranate provides the insight into its metal storage capacity Crystal structure of human pepsin and its complex with pepstatin University of Oxford Advanced Research Computing A single regulator mediates strategic switching between attachment/spread and growth/virulence in the plant pathogen Ralstonia solanacearum System-wide hypersensitive response-associated transcriptome and metabolome reprogramming in tomato Investigations on VELVET regulatory mutants confirm the role of host tissue acidification and secretion of proteins in the pathogenesis of Botrytis cinerea An integrated analysis of mRNA and sRNA transcriptional profiles in tomato root: insights on tomato wilt disease (2020) Extracellular proteolytic cascade in tomato activates immune protease Rcr3 Activity-based protein profiling: the serine hydrolases oryzicola infecting rice reveals novel insights into bacterial-plant interaction Specific hypersensitive response–associated recognition of new apoplastic effectors from Cladosporium fulvum in wild tomato (2001) Solution structure of BSTI: a new trypsin inhibitor from skin secretions of Bombina bombina Putative novel effector genes revealed by the genomic analysis of the phytopathogenic fungus Fusarium oxysporum f physali (Foph) that infects Cape gooseberry plants Host-induced bacterial cell wall decomposition mediates pattern-triggered immunity in Arabidopsis Cleavage of a pathogen apoplastic protein by plant subtilases activates host immunity Cladosporium Avr2 inhibits tomato Rcr3 protease required for Cf-2-dependent disease resistance (2012) Dual disease resistance mediated by the immune receptor Cf-2 in tomato requires a common virulence target of a fungus and a nematode The Ustilago maydis effector Pep1 suppresses plant immunity by inhibition of host peroxidase activity AF2Complex predicts direct physical interactions in multimeric proteins with deep learning Accurate prediction of protein structures and interactions using a three-track neural network Evolutionary-scale prediction of atomic-level protein structure with a language model PAE viewer: a webserver for the interactive visualization of the predicted aligned error for multimer structure predictions and crosslinks Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution US-align: universal structure alignments of proteins SeqKit: a cross-platform and ultrafast toolkit for FASTA/Q file manipulation Centrifuge: rapid and sensitive classification of metagenomic sequences Trimmomatic: a flexible trimmer for Illumina sequence data Near-optimal probabilistic RNA-seq quantification Exploring genetic variation in the tomato (Solanum section Lycopersicon) clade by whole-genome sequencing The de novo reference genome and transcriptome assemblies of the wild tomato species Solanum chilense highlights birth and death of NLR genes between tomato species Genome of Solanum pimpinellifolium provides insights into structural variants during tomato breeding clone sequences and assembly contigs with BWA-MEM The sequence alignment/map format and SAMtools association mapping and population genetical parameter estimation from sequencing data The genome analysis toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data Martin, M. et al. WhatsHap: fast and accurate read-based phasing. bioRxiv https://doi.org/10.1101/085050 (2016) Automated generation of heuristics for biological sequence comparison Assembly of designer TAL effectors by Golden Gate cloning A golden gate modular cloning toolbox for plants Rapid migration in gel filtration of the Cf-4 and Cf-9 resistance proteins is an intrinsic property of Cf proteins and not because of their association with high-molecular-weight proteins A simple and efficient protocol for the production of recombinant cathepsin V and other cysteine cathepsins in soluble form in Escherichia coli Download references We like to thank Urszula Pyzio for excellent plant care Sarah Rodgers and Caroline O’Brian for excellent technical support; Dr Jiorgos Kourelis for constructing pJK187; Dr China) for providing expression data of XOC_0943 in rice; Dr Nattapong Sanguankiattichai for excellent suggestions and the Advanced Research Computing (ARC 2015) facility of the University of Oxford for access to their high-performance computing cluster This project was financially supported by Clarendon fund and the Interdisciplinary Doctoral Training Program (DTP) of the BBSRC (project DDT00060 and ERC-2020-AdG project ‘ExtraImmune’ (project 101019324 These authors contributed equally: Felix Homma produced candidate inhibitors and P69B and performed inhibition experiments; R.H wrote the manuscript with input from all authors The funding body had no influence on the design of the study and collection and interpretation of data and in writing the manuscript The authors declare no competing interests Nature Communications thanks Andreia Figueiredo and the other reviewer(s) for their contribution to the peer review of this work Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Download citation DOI: https://doi.org/10.1038/s41467-023-41721-9 Anyone you share the following link with will be able to read this content: a shareable link is not currently available for this article Sign up for the Nature Briefing: Microbiology newsletter — what matters in microbiology research Jeanette Hoorn is a Professorial Fellow of Art History at the School of Culture and Communication Recent mining blasts at a sacred site in Western Australia have fired up protestors A recent ban on climbing the sacred rock in Australia’s ‘red centre’ was celebrated with singing and dancing What other forms of art have emerged from the site Irina Dumitrescu Claudia Tobin Michael Prodger Tim Smith-Laing Apollo This episode explores an ancient funeral stele and how digital technologies are helping to preserve Egyptian heritage sites A lawsuit filed this month in Alexandria calls a Catholic priest a "diseased pedophile who raped and sexually assaulted many young boys." The priest was among 27 named in a February 2019 letter from Bishop David P Talley as having credible accusations of sexual abuse against minors.  The lawsuit claims Van Hoorn was "moved frequently throughout the various parishes of the Diocese of Alexandria." The Diocese of Alexandria is the sole defendant named in the lawsuit and a Friday email and telephone message seeking comment weren't immediately answered Lawsuit: Fired Alexandria Police lieutenant expected to file lawsuit after appeal denied The victim is referred to only as Lou Doe. The alleged abuse against Doe happened in 1962-63 while the child was in the first or second grade The Doe family's children attended Sacred Heart of Jesus School in Pineville during the 1960s A Diocesan Permanent Review Board comprised of clergy and lay people dug into 535 files of clergy who worked in the diocese in its various configurations dating back to its 1853 establishment Talley's list didn't detail where the priests worked but did give details about the allegations against them Van Hoorn was accused in the sexual abuse of two minor males It's not known if the case from this lawsuit is from the other allegation against Van Hoorn who was suspended from active ministry in 1979 and retired as a priest in 1983 The lawsuit states that Doe and family were devout Catholics who became friends with Van Hoorn since the children attended Sacred Heart spent almost his entire career with the diocese and in Louisiana Church abuse: Investigation finds 27 local priests accused of sexual abuse Van Hoorn "ingratiated" himself to the family becoming friends with the parents by giving gifts to them and the children He often stayed at their home for dinner and sometimes overnight the priest even recuperated at the family's home after "electroshock treatments for significant emotional and psychological disorders," it reads The alleged abuse happened at the family's home Doe later sought professional help until late last year once he became sure it was Van Hoorn who had abused him Town Talk archives provide details about Van Hoorn's service within the diocese Our Lady of Prompt Succor in Alexandria and Immaculate Heart in Tioga details plans to honor Van Hoorn for his 20th anniversary in the priesthood he was assistant pastor at Immaculate Heart in Tioga A dark photo with the article shows Van Hoorn sitting at a desk in front of a typewriter The lawsuit accuses the diocese of multiple counts of negligence fraudulent concealment and being a public nuisance It alleges that the diocese has not been open regarding Van Hoorn's history and kept specific allegations against him from the public and parishoners for years Business: Alexandria Farmers Market returns to Jackson Street location Tuesday It contends that and other actions go against the so-called Dallas charter a policy enacted in 2002 by the United States Conference of Catholic Bishops It claims the diocese didn't reach out to any of Van Hoorn's alleged victims and that the diocese "has attempted to impugn victims' credibility character and veracity in direct contradiction of those pronouncements." At least one other lawsuit has been filed against a priest on the list released last year by the diocese a man identified as Paul Doe filed the lawsuit accusing the late Rev William Allison of sexually abusing him when he was a primary school student at Our Lady of Fatima in Monroe a skinsuit and more all contributed to the Dutchman's surprise victory It’s rare to see a lone breakaway rider outfox the peloton on a sprint stage at a Grand Tour so it was fantastic to see Taco Van Der Hoorn (what a great name by the way) of Team Intermarché - Wanty - Gobert Matériaux take a win on stage three of the 2021 Giro d’Italia To understand why events like this are so rare How can one rider overcome the collective strength of the teams working together to bring everything back together in time for a sprint finish and Van Der Hoorn expertly exploited the brinkmanship taking place between the top sprint teams It also looked very much like the peloton underestimated the Dutch rider’s strength giving him too much leeway without realising he had the firepower to make the move stick It was also an exciting victory for us tech nerds because Van Der Hoorn was using a highly optimised clothing and bike setup With a final gap of just four seconds over the chasing peloton I’d argue those optimisations were absolutely crucial to his victory that’s not to take anything away from his physical performance But racing is about combining brains and brawn and Van Der Hoorn clearly has both in spades The rider is the biggest cause of aerodynamic drag in the rider plus bike system, accounting for around 80 per cent of the total Anything you can do to improve the way the air flows over your body can make a significant difference to how much power is required to ride at a given speed you’ll be able to ride faster for the same effort Van Der Hoorn has clearly done his research, because his position of riding in a tucked down position, with his hands on the hoods and forearms parallel to the ground, is one of the fastest positions available on a road bike When we tested this position in a velodrome we found it saved a whopping 94 watts when riding at 45kph versus riding with straight arms on the hoods #AeroGainz don’t come much bigger than that is also something we’re increasingly seeing throughout pro cycling You can see how much more narrow Van Der Hoorn’s arms are compared to his breakaway companions and narrow equals fast as it reduces your frontal aera Part two of optimising the aerodynamics of your body is aero clothing and kit Van Der Hoorn has been meticulous in his clothing choices with both halves of the garment sewn together to reduce drag It also uses fabrics designed to be skin tight and aerodynamically efficient at race speeds On top of this, Van Der Hoorn was also using aero overshoes like those we would normally see used for time trials he was wearing arm warmers made out of an aerodynamic fabric too When it comes to saving energy for that big attack every little helps and it starts right from kilometre 0 On top of all this, Van Der Hoorn was wearing an aero road helmet and he’d even taken the time to tape over the vents on the front While an aero road helmet is a decent drag-reducing tactic (the difference between a Specialized Prevail and a Specialized Evade is apparently around 11 watts at 45kph) the latter detail may be a bit more hit and miss Continuing on the ‘aero is everything’ theme, Van Der Hoorn was also riding a full-on aero road bike, the Cube Litening C:68X, which is said to reduce aerodynamic drag by 30 per cent compared to the previous, non-aero-optimised Cube Litening fully hidden cables and a slippery integrated handlebar and stem Though the body is the largest contributor to aerodynamic drag the bike accounts for around 20 per cent of total drag which apparently equates to about 3 seconds per kilometre product manager for bicycle tyres at Continental Van Der Hoorn's team performed its own testing and found a 12 watt difference at 45kph between the GP5000 TL tubeless tyres and the Continental Competition tubulars they had been using previously Departments The DCS cohort is an on-going population-based cohort including almost all people with type 2 diabetes (T2D) in the catchment area of the DCS a primary care setting in the West-Friesland area of the Netherlands participants receive a standardized annual assessment with measurement of diabetes-related risk factors and complications The resulting database included 13,955 people with T2D in 2017 The study has been approved by the Medical Ethical Review Committee of the VU University Medical Center Individuals were informed about the use of their data and were offered an opt-out A description of the DCS cohort has been published previously You can find more information on the Hoorn studies cohort website Meta-data of this cohort can be found on the website of GECCO APH contact persons: Petra Elders, Joline Beulens, Amber van der HeijdenContact: p.elders@amsterdamumc.nl Location AMCMeibergdreef 91105 AZ AmsterdamPhone number:(020) 566 9111 Route & Parking De Boelelaan 11171081 HV AmsterdamPhone number:(020) 566 9111 Route & Parking Contact us Emergency services searched in vain for a swimmer missing off the coast of Scheveningen at the Zuidelijk Havenhoofd on Sunday evening The swimmer went into the sea with three others but disappeared around 8:30 p.m The other three were rescued from the water Another person is missing in the Markermeer after a boat capsized between Hoorn and Edam The emergency services responded to the Zuidelijk Havenhoofd with helicopters and boats after the report of the swimmers in trouble. They called off the search for the last missing swimmer when it got too dark to see, said the local security office, Haaglanden Veilig An eyewitness saw rescue workers pull two “boys” out of the water. “They both had legs covered in blood. There was also a mother there who was panicking and screaming,” the witness told Omroep West. According to them, the boys tried to save the missing swimmer but couldn’t get close. “The water was so wild, really impassable. Those boys barely survived.” The rescued swimmers were taken to the hospital. Their current condition is unknown. Another person is missing in the Markermeer after a boat capsized between Hoorn and Edam at around 5:15 p.m. on Sunday, a spokesperson for the police confirmed to ANP. The boat had four people on board, three of whom ended up in the water. One managed to get back on board under their own power, and the rescue society KNRM rescued the second. The coast guard launched a large search for the missing person but had to call it off without success when it became too dark to see. The police will continue the search on Monday. © 2012-2025, NL Times, All rights reserved. ​CategoriesCategoriesEnglishGENERALDe Hoorn brewery celebrates 100th anniversary6 November 2023 De Hoorn brewery in Leuven will celebrate its 100th anniversary with a week of festivities. De Hoorn was where the first Stella Artois was brewed in 1926. There will be parties on Monday and Tuesday evening and guided factory tours for 1,600 people on Wednesday and Thursday. On Thursday evening, 100 residents of Leuven will be served a "beer pairing" dinner in the old brewery. The week will culminate in a party for 800 people on Friday. To celebrate this milestone, parent company AB InBev is launching special editions of Stella Artois cans, and the drink will be servied in vintage glasses in more than 1,000 bars and cafés throughout Belgium. "We wanted to pay tribute to the packaging of yesteryear, including the original logo from 1964 and the typical Stella Artois colours: red, white and gold,” says Olivier Maillet, director of the Stella Artois brewery in Leuven. ©Ab InBevThe brewing activities of AB InBev date back to the 14th century but it was in the early 20th century that Stella was born De Hoorn was the base for brewing Stella until production moved to its current location where the beer is made with the same recipe The De Hoorn buildings remained empty following the move until 2012 when seven Leuven residents reopened it De Hoorn is now a well-known venue for parties and corporate events "AB InBev has gone from a small company to a globally known brewer," said city councillor Lalynn Wadera on Monday at the start of the festivities "The company has always had the ambition to be innovative #FlandersNewsService | © PHOTO BELGIAN FREELANCE Copy linkGet updates in your mailboxYour email addressSubscribeBy clicking "Subscribe" I confirm I have read and agree to the Privacy Policy rapid and high-quality information 24 hours a day from Belgium and abroad to all Belgian media not to mention entertainment and lifestyle our journalists and press photographers produce hundreds of photos and news stories Since the end of March 2022 English has been added as a language businesses and various organisations that need reliable information Belga News Agency also offers a comprehensive range of corporate services to meet all their communication needs www.belganewsagency.eu Sophomore Nick Hoorn has made a name for himself as Howell’s leading hitter but the biggest moment so far in his high school baseball career came on the pitcher’s mound On a day featuring great pitching performances in Livingston County Hoorn threw a no-hitter for the Highlanders Monday in a 2-0 victory over Canton The Chiefs’ only two base runners reached on errors Hoorn struck out 10 batters in seven innings and didn’t issue a walk throwing only 77 pitches in going the distance he’s 5-0 with a 1.52 earned run average and 35 strikeouts in 32⅓ innings Howell (19-10) took a 1-0 lead in the third inning when a double by Andrew Hiller scored Owen Elsey The Highlanders’ other run scored in the sixth when courtesy runner Brett Parris scored when an error was committed on a bunt by Landon Allen Easton Storey pitched a two-hitter and struck out 14 for his second straight shutout Storey hasn’t allowed a run in his last four outings giving up five hits and fanning 39 in 19 innings while Evan Larson and Jack Storey were each 2-for-4 with two RBIs for the Bulldogs (18-7) The Eagles’ runs scored on a double by Sam Clay in the first inning and a double by Gannon Grundman in the third After being denied a potential winning rally by a great defensive play in the first game Pinckney came back from a 3-0 deficit in the second game The Pirates (11-13) scored twice in the top of the seventh with singles by Talon Koppmann and Jonny Hoffman delivering the runs Landen Bauer gave up three runs in the first but settled down and didn’t allow a run in his final 4⅔ innings Nolan Carruthers pitched 1⅓ innings of no-hit scoreless ball Chelsea first baseman Luke Anstead made a diving stop on a hard ball hit down the line by Carruthers to end the game with the tying run on second base Hartland won its sixth consecutive KLAA championship with yet another blowout in the league’s title game The Eagles have outscored five opponents 81-13 in the league’s championship crossover game during that streak There wasn’t a title game in 2018 when Hartland went 8-0 in league play Jacob Ross had three goals and four assists Drew Lockwood had three goals and one assist and Joey Mattord scored twice for the Eagles Livonia trailed only 2-1 after one quarter before Hartland extended its lead to 9-1 by halftime and 12-1 through three quarters Nolan Hudnut stopped 13 out of 14 shots for Howell (13-4) which begins state tournament play at 7 p.m Ryan Tedesco had three goals and two assists Marshall Chambers and Sam Edwards scored Howell’s other goals Gage Overton had five ground balls and five takeaways on defense Hartland won its first KLAA championship since 2019 while Livonia lost in the final by a lopsided margin to a Livingston County team for the fourth straight season Ava Gilardone had five goals and two assists and Madeline Turcotte had four goals and two assists for Hartland Claire Pielack made 10 saves for the Eagles Tenth-ranked Hartland (22-2-1) lost for only the second time when Clarkston scored twice in the bottom of the eighth inning Kate McIntyre was 3-for-4 with two homers and five RBIs in the first game and 2-for-4 with two RBIs in the second game for the Eagles Kylie Swierkos pitched a five-inning shutout in the opener Brighton topped a strong 25-team field by shooting 299 at Plum Hollow Country Club in Southfield Howell ninth with a 330 and Hartland 15th with a 341 Brighton senior Andrew Daily finished first among 125 players Winston Lerch tied for fifth with a 74 and Matt Doyle tied for 39th with an 82 to complete Brighton’s score Zach Spencer tied for fifth with a 74 and Hayden Sturos tied for 27th with an 80 to lead Howell Brady Betteley tied for 35th with an 81 for Hartland Ella Swiderski scored off an assist from Zaryah Griffin as Pinckney completed SEC White play with a 9-0-1 record The Pirates will take a 38-game unbeaten streak in division play into next season They are 36-0-2 since losing 4-1 at Chelsea on April 30 6-4.Doubles: Payton McConnaughey-Morgan Thomas (F) d Loreyna Estrada-Robles-Olivia Delacruz 6-7 (3) 6-0.Doubles: Payton McConnaughey-Morgan Thomas (F) d 6-2; Addison Collard-Olivia Scrimger (O) d Underdog victories reaffirm our love for cycling and make us believe that anything is possible Then there isn’t one as good as Taco van der Hoorn and his against-the-odds victory Monday in Canale on stage 3 of the Giro d’Italia especially Peter Sagan and the Bora-Hansgrohe team thought the flying Dutchman was going to hold off a peloton that was determined on contesting a sprint finish I was thinking: ‘Is this real?’ I didn’t believe when we had one minute with 25k I just think that half-percent it’s enough chance and I just take it,” van der Hoorn said before stepping out on the podium to collect his prizes Also read: Who is Intermarché-Wanty-Gobert Matériaux? It was hard not to feel emotional while watching van der Hoorn celebrate at the finish, hand over his mouth as he tried to absorb just what he’d managed to achieve while the peloton loomed menacingly over his shoulder. Some may even have had a tear in their eye. Who can blame them? His victory was such that many of those beyond the line in Canale, even from outside his own team, broke into cheers as he rolled over the line. That van der Hoorn had come close to retiring on two occasions — once in 2017 due to a serious concussion and again over this winter as he struggled to find a contract — only added to the fairytale “My career was hanging by a thread then,” van der Hoorn said of 2017 “It was also the case at the end of last season when I was without a contract I persisted and I finally received my chance at Intermarché-Wanty-Gobert Matériaux It is the story of a man who never gave up despite the odds being stacked against him climbers and classics riders do what they do best There is a thrill in watching riders at the top of their game duke it out for the sport’s biggest prizes the rare opportunity when an unexpected rider can read between the lines of a script and write their own story That’s what van der Hoorn did Monday with his do-or-die attack It is days like Monday that make the sport of cycling so beautiful and the fact that they’re so rare also means they’re even more special but the success of an underdog is one of the few things that really unites us https://twitter.com/IntermarcheWG/status/1391777522245902337?s=20 It’s no surprise that Mat Hayman’s victory at Paris-Roubaix is considered one of the best editions of the legendary race – because nobody expected it Who can say that they did not cheer on Ian Stannard as he took on three Niki Terpstra and Stijn Vandenbergh — at the 2015 Omloop Het Niewsblad or Mads Pederson storming to a world championship title in Yorkshire in 2019 Also read: 2021 Giro d’Italia stage 3: Taco van der Hoorn solos to narrow win from an all-day break I think it is because we can see a little of ourselves in these underdogs We cannot all be the Tadej Pogačars and Annemiek van Vleutens of this world romping to success on a whim https://twitter.com/flobikes/status/1391806708528332802?s=20 Actress Kate Beckinsale once said: “Everybody likes the underdog because everybody feels like the underdog.” Seeing a rider like van der Hoorn succeed gives us all a little bit of hope that if we keep plugging away Cycling is full of riders who know they will never be the next Peter Sagan or Anna van der Breggen but keep doing the hard yards because they love it and because they believe that one day they can enjoy their moment in the sun Those days are few and far between in a sport as brutal and unforgiving as cycling it further reaffirms our love for the sport and makes us believe that anything is possible .st1{fill-rule:evenodd;clip-rule:evenodd;fill:#2a2a2a}By Fritz Klug | fklug@mlive.comView full sizeCourtesy PhotoBradley Hoorn receiving his diploma from William Sledge the former Master at Calhoun College at Yale University in 2001 Hoorn worked in the World Trade Center and was killed during the Sept Sledge helped drive the process to establish the Brad Hoorn Memorial Fund.WASHINGTON — Ten years have passed “It’s like it happened yesterday,” Kathy Hoorn said of the death of her son who was working in New York City when a hijacked plane struck the north tower of the World Trade Center on the 10th anniversary of the 9/11 attacks families across America will remember the 2,977 people who died in attacks in New York which crashed in a rural Pennsylvania field takes one day at a time and enjoys everything it has to offer but we’re not sitting at home feeling sorry for ourselves,” she said “We do the best we can with the lives we have.” who roomed with him at Yale University and in New York Sion said today’s anniversary is a somber reminder of how much potential was lost when the twin towers fell who he called “the nicest and most genuine guy.” “It’s a call to live your life to the fullest in honor of those who never had a chance to,” said Sion a 31-year-old financial services consultant who now lives outside Washington Hoorn was the type of person who could do whatever he put his mind to Hoorn passed the first level of the certified financial analyst exam which is normally taken by people three to four years older than him Only about half of the people who take the exam pass Hoorn then got a job as a financial analyst at Fred Alger Management Inc. three others in that company were born and raised in Michigan he was earning a six-figure salary right out of college Hoorn had purchased a 1987 red Porsche 911 during his senior year at Yale Cars were a lifelong passion for his roommate “It’s one of the things I’m really glad he was able to get before passing away,” Sion said Sion was on the subway heading to a training session for his job at Lehman Brothers when American Airlines Flight 11 crashed into the north tower The training was canceled after United Airlines Flight 175 crashed into the south tower Sion went to Battery Park and saw the smoke billowing from the twin towers He couldn’t use his cell phone for the rest of the day “It was a huge reality check when I got to the apartment and he wasn’t there,” Sion said “That’s when I started to really get concerned With all the uncertainty and catastrophe at the time Sion said it was also a time when New Yorkers came together to help each other as crazy as it was not to know on a daily basis where Brad was for some time that was probably the most amazing glimpse of humanity in that month or so in New York I have ever seen,” Sion said that remarkable reaching out has continued since Hoorn’s death: Hundreds of people have made contributions to the Brad Hoorn Memorial Endowment Fund established in October 2001 with the Kalamazoo Community Foundation Another fund in Hoorn’s memory also was established by Yale The Kalamazoo endowment fund currently has about $90,000 and provides grants to area education programs such as the Kalamazoo Area Mathematics & Science Center and Gull Lake Community Schools a donor relations officer at the foundation Memorial funds aren’t the only way the victims are being remembered a decade after the attacks they will be honored during the dedication at ground zero of the Sept Three other people with ties to Southwest Michigan died in the attacks on that day: Peter Edward Mardikian had family who lived in Portage; and Barbara Edwards was a 1965 graduate of Western Michigan University whose parents then lived in the Hopkins area But all of the victims “were unique and special individuals with so much more to give,” Hoorn’s aunt said at a remembrance event in Bronson Park on Sept “Please continue to be aware that there are still issues of national security ever-present with us in America Contact Fritz Klug at fklug@kalamazoogazette.com or 269-388-2733 Use of and/or registration on any portion of this site constitutes acceptance of our User Agreement, (updated 8/1/2024) and acknowledgement of our Privacy Policy, and Your Privacy Choices and Rights (updated 1/1/2025) © 2025 Advance Local Media LLC. All rights reserved (About Us) The material on this site may not be reproduced except with the prior written permission of Advance Local Community Rules apply to all content you upload or otherwise submit to this site YouTube's privacy policy is available here and YouTube's terms of service is available here Ad Choices The TimesLast year was supposed to herald the moment when we made peace with our bodies Plus-size models in ad campaigns; realistic-looking boobs bellies and bums in underwear shoots; and record numbers of what the fashion industry calls “curve bookings” on the catwalk hang-ups; hello to letting it all hang out – during the heatwave months of the summer I noticed young women dressing for comfort and cool with none of the self-consciousness around size that was drilled into my generation and with it a revival of the now vintage crop tops ultra-low-rise jeans and body-hugging dresses of my teenage years in the late Nineties and early Noughties it isn’t just those of us who wore them the first time Filippo Ganna defended his overall position on the 90th anniversary of the awarding of the maglia rosa Taco van der Hoorn (Intermarché-Wanty-Grobert-Matériaux) soloed to victory on stage 3 of the 2021 Giro d’Italia With the big bunch breathing down his neck at 200m to go van der Hoorn notched his first grand tour win — and the first win for his team’s WorldTour debut — as the only man remaining from an all-day break I was thinking: ‘Is this real?’” van der Hoorn said from the podium “I didn’t believe when we had one minute with 25k I just think that half-percent it’s enough chance and I just take it.” Also read: Who is Intermarché-Wanty-Gobert Matériaux? Bora-Hansgrohe spent the majority of the stage on the front of the chasing peloton and while the German squad did not contest the win Peter Sagan held Elia Viviani (Cofidis) to take third on the day while David Cimolai (Israel Start-Up Nation) scored the second step on the podium “I think we had the perfect strategy for today and the team worked very well to execute it I’d like to thank all my teammates for their tremendous effort they worked so hard to try our chance at the stage win Overall race leader Filippo Ganna will spend another day in the maglia rosa successfully defending his advantage established on the first stage time trial https://twitter.com/INEOSGrenadiers/status/1391774219315388417 A group of eight had built up a four-and-a-half-minute gap with 100 kilometers to go Vincenzo Albanese (Eolo Kometa) in the blue jersey of the leader of the climbing competition was in the break and made a run at the stage’s climbing contest through 40km to go Giacomo Nizzolo (Qhubeka-Assos) in the chasing group appeared confused — or misinformed — and launched an unmatched sprint only to sit up when he came through the checkpoint after the break had already taken all the sprint points available.sag The acceleration for the intermediate points blew up the break when Albanese attacked and a touch of wheels brought down two Eolo riders and an Intermarché rider Dylan Groenewegen (Jumbo Visma) still finding his legs after a nine-month suspension was spit out of the main bunch along with stage 2 winner Tim Merlier (Alpecin-Fenix) and Thomas De Gendt (Lotto Soudal) who may have been intentionally trying to save his legs and also lose overall time so that he can go unnoticed in attacks later in the three-week race Andrii Ponomar (Androni Giocattoli–Sidermec) who had been on the front and attacked at 75km to go looked to be spent and was shed from the break and was moving backward when the main bunch caught him Caleb Ewan (Lotto-Soudal) dropped back from the Peloton with Ponomar not to contest the sprint at the end of the stage The German-based Bora-Hansgrohe circled around Peter Sagan and Emanuel Buchmann Ineos-Grenadiers were happy to let the squad do the pace-making with overall leader Filippo Ganna tucked in at 12th wheel Bora-Hansgrohe lead the chase over an undulating route with two categorized climbs remaining The tempo was too much for Giacomo Nizzolo (Israel Start-Up Nation) who popped off the peloton at 38km to go https://twitter.com/QhubekaAssos/status/1391349625362296835 just five remained on the front on the final climb of the day The pace forced attrition on the front of the race and just a minute separated the chasing peloton at 20km to go from the three remaining on the front Giulio Ciccone (Trek-Segafredo) and Tony Gallopin (AG2R-Citroën) launched a move to bridge to the front when only Simon Pellaud and van der Hoorn remaining in front of their pursuers Van der Hoorn dropped his break-mate and pressed on stretching a 30-second advantage over the Gallopin group The final 3km was undulating and highly technical and the Dutch rider’s advantage was whittled to just 19 seconds in the final kilometer The former Jumbo-Visma rider put his head down and toughed out for his biggest career win and his team’s first WorldTour victory https://twitter.com/IntermarcheWG/status/1391771757158223882 will shift focus from the sprinters and time trialists to the climbers finishing in Sestola after an ascent of 4km averaging 10 percent that comes just 2.5km from the line Results provided by ProCyclingStats