Text description provided by the architects. Moke Architects has designed a wooden house in Muiden together with la4sale
The living/working house of the two founders of the la4sale landscape agency had to have a 'landscape' appearance based on the nature of the residents
The house has a visible wooden construction
The house designed by Gianni Cito and the partners of la4sale is located directly behind the dike of the IJmeer
in the new residential area near Amsterdam
The residents wanted a house where they could enjoy the view
The house is divided into a front and rear house offset from each other; an idea suggested by the residents
Ecohouse made of Wood - The new living/working house of two designers with a landscape architecture practice seems to have emerged naturally in its green surroundings. The house with a visible wooden construction, pergolas, views and a greenhouse on the roof is located in the old port town of Muiden, directly behind the dike of the Ijmeer near Amsterdam.
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European Commission granted approval of Nubeqa™ (darolutamide) for the treatment of patients with metastatic hormone-sensitive prostate cancer (mHSPC) / Approval is based on Phase III ARASENS trial data
2023 – The European Commission has granted marketing authorization in the European Union (EU) for Nubeqa™ (darolutamide)
plus androgen deprivation therapy (ADT) in combination with docetaxel
for the treatment of patients with metastatic hormone-sensitive prostate cancer (mHSPC)
Nubeqa is already approved for the treatment of patients with non-metastatic castration-resistant prostate cancer (nmCRPC)
who are at high risk of developing metastatic disease
“Today’s approval of Nubeqa represents a significant milestone in addressing unmet medical needs for people living with metastatic hormone-sensitive prostate cancer in Europe,” said Christine Roth
Member of the Executive Committee of Bayer’s Pharmaceuticals Division and Head of the Oncology Strategic Business Unit
“We are committed to improving prostate cancer care across all stages of the disease and recognize that for patients and their families
quality of life is just as critical as prolonging survival and delaying disease progression
We continue in our mission to redefine what it means to live with prostate cancer.”
The EU approval is based on the positive results from the Phase III ARASENS trial
which demonstrated that darolutamide plus ADT in combination with docetaxel significantly reduced the risk of death by 32.5% compared to ADT with docetaxel
the darolutamide combination showed consistent benefits across clinically relevant secondary endpoints
with the overall incidence of treatment-emergent adverse events being similar between treatment arms
“The approval of Nubeqa in mHSPC in Europe is a major step forward for patients and their treating physicians
expanding the treatment options available and our ability to improve clinical outcomes for those living with the disease,” said Prof
Professor of Urology at the Université catholique de Louvain (UCL)
“This approval is supported by robust data from the ARASENS clinical trial
which demonstrate the benefits of darolutamide plus ADT in combination with docetaxel in extending survival
delaying disease progression and maintaining quality of life for patients with metastatic hormone-sensitive prostate cancer.”
Prostate cancer is the most commonly diagnosed cancer in men in almost all northern and western European countries.1
Only 30% of men with mHSPC will survive five years or more after diagnosis.2 Most men with mHSPC eventually progress to metastatic castration-resistant prostate cancer (mCRPC)
a condition with limited long-term survival.3,4
Nubeqa is being investigated in a broad development program with an additional three ongoing or planned large clinical studies
to investigate its potential across prostate cancer patients from the early- to the late-stage of this disease
This includes the ARANOTE Phase III trial evaluating darolutamide and ADT versus ADT alone for mHSPC
Nubeqa is developed jointly by Bayer and Orion Corporation
a globally operating Finnish pharmaceutical company
Bayer is responsible for global commercialization
with co-promotion from Bayer and Orion Corporation in certain European markets
About the ARASENS TrialThe ARASENS trial is the only randomized
trial which was prospectively designed to compare the use of a second-generation oral androgen receptor inhibitor (ARi)
plus ADT in combination with docetaxel to ADT plus docetaxel (a guideline recommended standard-of-care) in metastatic hormone-sensitive prostate cancer (mHSPC)
A total of 1,306 newly diagnosed patients were randomized in a 1:1 ratio to receive 600 mg of darolutamide twice a day or matching placebo
The primary endpoint of this trial was overall survival (OS)
Secondary endpoints included time to castration-resistant prostate cancer (CRPC)
time to first symptomatic skeletal event (SSE)
time to initiation of subsequent anticancer therapy
as well as adverse events (AEs) as a measure of safety and tolerability
Results from this trial were published in the New England Journal of Medicine.5 A plain language summary publication of these data was published in Future Oncology.6 The ARASENS trial demonstrated that darolutamide plus ADT in combination with docetaxel significantly reduced the risk of death by 32.5% compared to ADT with docetaxel alone.5 Improvements in the secondary endpoints supported the benefit observed in the primary endpoint
About Metastatic Hormone-Sensitive Prostate CancerProstate cancer is the second most commonly diagnosed malignancy in men worldwide
an estimated 1.4 million men were diagnosed with prostate cancer
and about 375,000 died from the disease worldwide.7
meaning their cancer is confined to the prostate gland and can be treated with curative surgery or radiotherapy
when the disease will metastasize or spread
the disease is hormone-sensitive and androgen deprivation therapy (ADT) is the cornerstone of treatment
Current treatment options for men with metastatic hormone-sensitive prostate cancer (mHSPC) include hormone therapy
androgen receptor pathway inhibitors plus ADT or a combination of ADT and docetaxel
a large proportion of men with mHSPC will eventually experience progression to metastatic castration-resistant prostate cancer (mCRPC)
a condition with high morbidity and limited survival
About Nubeqa™ (darolutamide)Nubeqa™ (darolutamide) is an oral androgen receptor inhibitor (ARi) with a distinct chemical structure that binds to the receptor with high affinity and exhibits strong antagonistic activity
thereby inhibiting the receptor function and the growth of prostate cancer cells
The low potential for blood-brain barrier penetration for darolutamide is supported by preclinical models and neuroimaging data in healthy humans
This is supported by the overall low incidence of central nervous system (CNS)-related adverse events (AEs) compared to placebo as seen in the ARAMIS Phase III trial and the improved verbal learning and memory observed in the darolutamide arm of the Phase II ODENZA trial.8
a study to explore the potential of darolutamide in the early setting for patients who have experienced a rise in their prostate specific antigen (PSA) levels following surgery or radiation
About Prostate Cancer at BayerBayer is committed to delivering science for a better life by advancing a portfolio of innovative treatments
The company has the passion and determination to develop new medicines that help improve and extend the lives of people living with cancer
Prostate cancer is the second most commonly diagnosed cancer in men7 and a key area of focus for Bayer
The company’s franchise includes two products on the market (Nubeqa™ and Xofigo™) and several compounds in development
including a unique approach of advancing targeted alpha therapies
Bayer is focused on addressing the unique needs of prostate cancer patients
providing treatments that extend their lives throughout the different stages of the disease and allowing them to continue their everyday activities
Find more information at https://pharma.bayer.comFollow us on Facebook: http://www.facebook.com/bayerFollow us on Twitter: @BayerPharma
The company assumes no liability whatsoever to update these forward-looking statements or to conform them to future events or developments
1. The Cancer Atlas: Europe. 2018. https://canceratlas.cancer.org/the-burden/europe/https://canceratlas.cancer.org/the-burden/europe/
2. Ng, K., Smith, S., Shamash, J. Metastatic Hormone-Sensitive Prostate Cancer (mHSPC): Advances and Treatment Strategies in the First-Line Setting. Oncol Ther. 2020;8:209–230. https://doi.org/10.1007/s40487-020-00119-z
3. Siegel DA, O’Neil ME, Richards TB, Dowling NF, Weir HK. Prostate Cancer Incidence and Survival, by Stage and Race/Ethnicity — United States, 2001–2017. MMWR Morb Mortal Wkly Rep. 2020;69:1473–1480. http://dx.doi.org/10.15585/mmwr.mm6941a1
4. Hahn AW, Higano CS, Taplin ME, Ryan CJ, Agarwal N. Metastatic Castration-Sensitive Prostate Cancer: Optimizing Patient Selection and Treatment. Am Soc Clin Oncol Educ Book. 2018 May 23;38:363-371. https://doi.org/10.1200/edbk_200967
5. Smith M.
6. Smith M., Hussain M., Saad F. et al. Darolutamide and survival in metastatic, hormone-sensitive prostate cancer: a patient and caregiver perspective and plain language summary of the ARASENS trial. Future Oncol. 2022;18:21:2585-2597. https://doi.org/10.2217/fon-2022-0433
7. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA: Cancer J Clin. 2021;71:209–249. https://acsjournals.onlinelibrary.wiley.com/doi/epdf/10.3322/caac.21660. Accessed December 2022
8. Colomba E
cross-over phase II trial of preference between darolutamide and enzalutamide in men with asymptomatic or mildly symptomatic metastatic castrate-resistant prostate cancer (CRPC)
Quotes[last lines]
Buchverkäufer: 29.80
Hauptmann Gerd Wiesler: No. It's for me.
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healthy people with symptoms of covid-19 can help to prevent outbreaks in emergency rooms where our society’s sickest will be seeking care
As we begin to see bigger outbreaks in more major cities globally
particularly while we do not have a vaccine
healthy patients with mild symptoms of fever
and shortness of breath who may have covid-19 to avoid going to the emergency room
and in that case they would need to be seen in a hospital—but the vast majority will not
This simple action by the young and healthy could help prevent community spread but
prevent outbreaks in emergency rooms where our society’s sickest will be seeking care for both covid-19 and other medical conditions
do not have the capacity to handle this level of hospitalisations if covid-19 spreads to even a small percentage of our societies
The hope is that these hospitalisation rates will turn out to be much lower
especially because early on in an epidemic
reporting mechanisms tend to catch many more severe cases and undercount the mild or asymptomatic cases
health systems will need to employ large scale channels of communication
by which they can easily contact all people to reinforce these critical messages
doctors can screen people who think that they are at risk by asking basic checklist items
and comorbidities while people are in the safety of their homes
This will allow healthcare professionals to quickly decide who actually needs to be evaluated in the emergency room
and who should remain at home where they can safely recover and limit the risk of infecting other people
One obstacle is that many people do not have access to primary care doctors
health systems need to have call lines by which all people can reach a physician
or other healthcare professional to begin screening
Community home testing will be an important step if initial screenings are suspicious for covid-19
Another considerable concern is that self-isolation for 14 days puts people out of work—an impossible prospect for the many people who can’t afford this luxury
The economic consequences will be severe if a large proportion of any society cannot work
and this is something that political and economic thought leaders need to address
We need many things right now—rapid diagnostics
antivirals with proven benefit—but these could take several months to materialise
We have to instead rely on what we do have at this moment
which is our ability to communicate effectively at scale
minimise spread of disease by self-isolating appropriately
and freeing up valuable medical resources to be focused on those who will need them most
Abraar Karan is an internal medicine doctor at Brigham and Women’s Hospital and Harvard Medical School. The views expressed here are his own and do not represent those of his employers. Twitter @AbraarKaran
BMJ Opinion provides comment and opinion written by The BMJ's international community of readers
and appeal to our international readership of doctors and other health professionals
The best pieces make a single topical point
For more information on how to submit, please see our instructions for authors.
the International Organization for Migration (IOM) carried out Round 18 of the General Population Survey (GPS)
which offers a highly representative assessment of internal displacement in Ukraine
was gathered by 61 enumerators from Multicultural Insights through screener phone-based interviews involving 40,002 randomly selected respondents
alongside follow-up interviews with 1,421 internally displaced persons (IDPs)
These interviews were conducted using the computer-assisted telephone interview (CATI) method and a random digit dial (RDD) approach
This report presents the main findings from Round 18 of the GPS
providing detailed insights into population figures
analysis of displacement flows and mobility intentions
These insights aim to support evidence-based decision-making on strategic
and programmatic aspects of the response and recovery efforts in Ukraine
located in the Netherlands was cut in half and has been turned into an artistic war memorial
the bunker was supposed to hold up to 13 soldiers during bomb raids
It was one of the (many) small hiccups in the New Dutch Waterline
This was an expansive series of water-based defenses that dated all the way back to 1815
With the help of Dutch Studios RAAAF and Atelier de Lyon
the bunker was able to be split through the middle
This has created a unique war memorial for World War II
The New Duch Waterline was meant to be used 1940 to protect the Dutch cities of Muiden
The waterline was to flood the area with water as a means of protection
Bunker 599 was one of 700 built to bolster the virtually obsolete fortresses built after 1815
After 40 long days of cutting through the concrete
it now stands apart from the rest as a tourist attraction and a war memorial
“Our aim with the project was to question the policies on monuments by doing this intervention,” said Ronald Rietveld of RAAAF
Looking up to the bunker across the bridge
Inside the bunker
It looks great in the snow too
Source of all images: http://www.raaaf.nl/nl/projects/7_bunker_599
Evette Champion is one of the authors writing for WAR HISTORY ONLINE
A former employee of Canadian fashion mogul Peter Nygard says he sexually harassed
A Fifth Estate investigation reveals how members of the Winnipeg business elite assisted in suppressing the details of Jonna Laursen’s story — a story that is now being fully told for the first time in 40 years
Jonna Laursen risked everything to make her Canadian dream come true
[Peter] Nygard of TanJay was charged with raping a girl.… And I was like
Laursen was assured by her manager there was nothing to the allegations
successful and often the target of young women trying to make quick money
An investigation by CBC's The Fifth Estate reveals how Manitoba's largest daily newspaper
killed a plan to publish Laursen's story in 1996 and how Nygard's influence assisted in keeping her allegations against him under wraps for more than 40 years
Nygard’s Winnipeg-based company was already hugely successful
as an immigrant from Finland who arrived in Canada in 1952 as a boy with nothing
“I realized early in my life that you must set your goals - you’ve got to get your head in the right direction,” Nygard told the CBC in an interview in 1979
But it didn’t take long for her to regret the decision to work for Nygard
She was exposed to the same kind of harassment that many other Nygard employees would report to CBC
“My first impression was she was very competent
Laursen remembers walking into TanJay headquarters on her first day of work and seeing the walls plastered with posters of Peter Nygard
She said Nygard approved almost every decision at the company
she was promoted to head up the design at one of his divisions
but she said eventually his support came at a price
It was on one of those trips where she says her life changed forever
Laursen admits the whirlwind itineraries of those trips to Asia are now a blur
she believed the incident with Nygard occurred in Taipei
and at another point she thought it was in Hong Kong
But the details of what happened that night are seared into her memory
She remembers being shown her room by the hotel manager
In the middle of the night she woke up with a shock
she felt like she had no choice but to carry on with the company
a senior executive who was travelling with her
When The Fifth Estate reached the executive
he said he didn’t remember Laursen telling him what happened
she said Nygard never physically assaulted her again
but she was uneasy every time he was around her
Until one day 15 years later when Laursen got a call from a reporter with the Winnipeg Free Press
Catherine Mitchell had been working at Winnipeg’s largest daily paper for a decade
when the newspaper received a tip that haunts her to this day
Three of those women had gone to the Manitoba Human Rights Commission with serious complaints about their boss
According to their 1996 report in the Winnipeg Free Press
Nygard’s company paid about $20,000 to settle three sexual harassment complaints
The complaints against Nygard included adding “skinny dipping” to a meeting agenda
that he “frequently was grabbing himself,” and that he would call a female employee into his office while in a “state of undress.”
She remembers that the newsroom was “solidly behind pursuing the story,” but the publisher was not
The decision was made at the time and we just have to live with it.”
CBC News detailed Laursen’s allegations in a letter to Nygard’s lawyers
Laursen is not one of the 57 women involved in the class-action lawsuit against Nygard
Prober warned the CBC that publishing the Laursen’s allegations would be “grossly unfair and illegal” and threatened to pursue the CBC “criminally” if it proceeded
Nygard was not involved in any attempt to stop the publication of a story about unreliable
he was given an award by the Winnipeg Chamber of Commerce for outstanding Canadian distinction
he was given the city’s community service award
wealthy and influential men are starting to be held accountable for sexual misconduct
A shift began in 2017 when more than 80 women came forward to accuse movie and television producer Harvey Weinstein of sexual misconduct
he was found guilty and sentenced to 23 years in prison
I never think that I really told her the details
But yet I feel good about her knowing it.”
Laursen and her daughter embrace once again
She looks out over the fjord and points to a building in the distance
CBC
Radio-Canada
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Jake Sims for Australian Defense Ministry)
SYDNEY — Australia, in the midst of what could be a hallmark strategic review, has officially delayed any decision on the country’s largest defense program until the review is complete early next year, raising serious questions about whether the program will be reduced in size
the top civilian at the Department of Defence
saying his department had combed through lessons from the illegal Russian invasion of Ukraine and warned of “hard choices” ahead
“We do have limited resources — and there will be hard choices to be made about priorities. Defense is committed to communicating with industry early to give certainty for business,” he told a conference at Parliament House in Canberra put on by the Australian Industry & Defence Network (AIDN), according to Asia-Pacific Defence Reporter
“We know that working with industry is the best way to meet the requirements of the ADF and to build the capabilities that we will need for the future.”
He reportedly pointed to command and control systems
precision strike capabilities and the need for robust logistics systems as key lessons learned from Ukraine
His comments made clear the stark strategic background against which the review is being conducted: “Australia needs to be able to preserve our freedom of action and to discourage and deter those seeking to disrupt the international rules-based order — especially through force
We see the need for capabilities to deter conflict — and in a worst case scenario
The war against Ukraine has highlighted this
“has already started thinking about how to implement the DSR [Defense Strategic Review] recommendations.” This will probably require a “comprehensive refresh” of what’s called the Integrated Investment Program
a broad swath of new capabilities and sustainment funding in the budget
“Some of these [priorities] will need to be accelerated — some other capabilities might be re-profiled
The review is expected to be completed in February by the department
who will make those choices and is expected to release the results in March
Among those programs that could see changes is the Infantry Fighting Vehicle program
is to buy 450 IFVs from either South Korea’s Hanwha or Germany’s Rheinmetall
But reports have been circulating for months that the number is now likely to be closer to 300
The decision to delay the decision on the IFV until the SDR is released was made Nov
25 by the minister for defense procurement
He was the one to decide because Defense Minister Richard Marles recused himself from all decisions on the IFV
as Hanwha has a large plant in this home district of Geelong
where the Redback would be built should Hanwha win
expected to be worth at least $18 billion AUD ($11.5 billion US)
One of the top defense procurement experts here
Marcus Hellyer of the Australian Strategic Policy Institute (ASPI)
said even those like himself who want to see “a lighter
more deployable army,” agree they need armor
But how much armor the island nation should have and how heavy it should be are key questions he expects the SDR to consider
“I don’t know how the force structure the army is now building can be moved to the fight and
There are signs the Royal Australian Army may not get as much armor as it wants
the well-connected foreign editor of The Australian
penned a mid-October op-ed sharply critiquing the army’s plan to buy 72 Abrams tanks and the fighting vehicles
We have not deployed a tank outside of Australia or anywhere near combat in more than 50 years,” he wrote
“We are planning to acquire 450 of the heaviest combat vehicles in the world
We cannot transport them effectively inside Australia as it is
We are acquiring infantry vehicles twice as heavy as those of the South Koreans
Our ships can carry only tiny quantities of them.”
In an interview with Sheridan on Nov. 4, Prime Minister Anthony Albanese said Australia would instead focus on missiles
He appeared to ridicule the basic tenet of the army’s argument that armor will be needed to defend the Australia landmass
known generically as the northern strategy since the assumption was that no one could possibly move many forces to attack the island continent’s soft underbelly
“Are we going to be involved in a land war in central Queensland
Will the SDR make big decisions and refocus Australia’s strategy on long-range fires
“It ultimately comes down to the ultimate question that we’re not really good at answering in this country — what are we really trying do with our military?” Hellyer said
where each service gets almost exactly as much as the others
will be bureaucratically and politically perilous
Moriarity said that the government is already focused on building resilient supply chains
along with acquiring stockpiles of high-end consumables
Resources — in other words money — will need to be found for this
Every existing program already has a sizeable constituency ready to defend it and a long-established precedent that no single service gets much more than the others
That would seem to either mean personnel costs need to be cut to buy new weapons — the traditional American approach to tight budgets — or larger programs without a constituency so far
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There were multiple violent incidents in the Netherlands overnight
and two got hurt in separate stabbings in Etten-Leur and Rozenburg
And two people got injured in shootings in Venlo and Muiden
The police responded to a report of a stabbing in a home on Leurse Dijk in Etten-Leur at around 5:00 a.m. on Friday. Responding officers found a body outside and two wounded people inside the home, the Breda police said on Twitter
Paramedics took the two wounded to a hospital
A man died in a stabbing on Raadhuisplein in Rozenburg at around 10:00 p.m. on Thursday. Two men got into an argument, which escalated into a stabbing, the police said
First responders tried to resuscitate the wounded man
One person got hurt in a shooting on Herengracht in Muiden at around 6:00 p.m. on Thursday. The police arrested one suspect and were looking for two others, the Gooi- en Vechtstreek police said on Twitter.
a person got hurt in a shooting in a parking lot on the square in the Blerick district around 10:00 p.m
The police are looking for the perpetrator and asked witnesses to come forward
ISPI
Amid the global turmoil caused by the COVID-19 outbreak
the Hashemite Kingdom of Jordan looked resilient in combating the virus outbreak
Jordan adopted harsh measures for the population and the economy with an unwavering intent to eliminate the virus
despite the proven efficiency of those measures in containing the virus
their economic impacts are still hard to fathom
These economic impacts show that Jordan’s real battle with the virus is not only on the health front but also on the economic front as well.To contain the virus
the government of Jordan enforced a nationwide curfew in mid-March
This measure brought the Jordanian economy to a standstill
with all economic activities shut down.
The shutdown provoked a shock to both sides of the economy
Jordanian businesses started to suffer interruptions in their cash flows which made it harder for them to meet their fixed costs (wages
Jordanian businesses started to search for possible ways that could help them reduce their costs until the economy operates again
67% of Jordanian employers considered laying off some of their workers if the shutdown continued for a longer period
according to a survey conducted by the Center for Strategic Studies at the University of Jordan
If this move is made by Jordanian businesses
it will add to the already high unemployment rates that had reached 19% by the end of 2019
this will mean a decline in already low aggregate demand on the Jordanian job market and hence a longer time for Jordanian businesses to recover
this will mean a drop in the Jordanian government’s tax revenues on business profits and consumption as well
a huge part of the Jordanian labor force works in the informal sector and most of them are day laborers
accounting for more than 52% of the Jordanian labor force
They are currently struggling to meet their daily financial needs.Besides the shutdown and its resultant consequences on Jordanian businesses and labor
COVID-19 will have a long-term negative impact on one of the most promising Jordanian sectors: tourism
This sector will be impacted not only by the shutdown
it will also be negatively impacted by the lower amount of trust and increasing cautiousness among international tourists about traveling abroad and global tourism
it’s expected that it will causes losses in a main source of foreign currency and job creation.Externally
Jordan is highly dependent on remittances from Jordanian workers abroad
Those cash inflows to the country are expected to decline due to the expected global economic recession
the government of Jordan will need a massive amount of funds – which are usually unavailable – to mitigate the emerging economic crisis
These funds will be needed to compensate the vulnerable groups like day laborers and informal workers and the government will need to subsidize private sector wages to sustain employment; finally
the government will need to increase its long-term capital spending to stimulate the economy and accelerate its recovery
securing these funds will not be an easy task for the Jordanian government
Jordan suffers from a chronic fiscal deficit and mounting public debt
The spending needed will increase the country’s public debt to risky levels that may jeopardize its credit rating
the main challenge will be the debt source and its cost: the options of getting this credit are few because the liquidity of international credit markets is drying up due to financial shock caused by COVID-19
The main options will be getting concessional loans from the World Bank and the IMF
the option will be getting credit from the local banks
getting credit from the local banks will exasperate the SMEs’ financing issues if the government is crowding them for the funds available in Jordan’s local credit market
Increased economic hardships for Jordan and perhaps a recession will be inevitable
what Jordan will need to look for is the acceleration of economic recovery
it needs to fight its economic battle maybe even harder than the health battle
Jordan needs to stimulate the sectors that were not impacted by the COVID-19 crisis
the Jordanian ICT sector was able to keep its businesses running where it was able to activate remote working and continue to export services
Such sectors could be the key drivers of the Jordanian economy if they were given the needed incentives to boost their production
these sectors could also absorb the newly unemployed workers of the sectors that were negatively impacted by COVID-19
customs duty exemptions and perhaps subsidies to the private sector
Yet these stimulus packages will be of tremendous cost to government finances and may add long-term pressure on the government’s budget
Jordan is living unprecedentedly exceptional days that necessitate exceptional measures
Jordan needs to be brave in stimulating the economy in the short run and much braver in implementing market reform in the future
This content was created by ISPI MED online analysts
French-language rap is having a political reawakening
was acquitted last year of charges of inciting religious hatred against Muslims
while French aid worker Moussa Tchantchiung was arrested and detained in Bangladesh in December while working with Rohingya refugees
Criticism of the government for not doing more to defend the Muslim French citizen became a cause; #FreeMoussa trended on social media for weeks
These are not the only political topics to have filtered into mainstream French hip-hop of late
Divisions along the lines of race and class in France’s main cities made hip-hop resonate with inner-city youth back in the 1980s
The groups Suprême NTM and IAM (both formed in 1989) rapped about police brutality
identity and life in Seine-Saint-Denis and Marseille
the second generation of rappers are experiencing many of the social problems that their parents had – life in the suburbs
racial profiling and poverty – but at the same time having to deal with the aftermath of the terrorist attacks in Paris
There is a general hostility towards far-right politics
Hip-hop fans are attracted to expression that is as much about engagement as it is entertainment
and the most successful rappers are those who can best work that balance
So while the rapper Médine zoned in on the hypocrisy of laïcité [secularity] in France
his work is often ignored by mainstream media
will often reference France’s colonial past and issues with race
French-Congolese rapper Youssoupha has been reluctant to be labelled as a “conscious” rapper
he makes a more subtle gesture in his video for Entourage
wearing a shirt that says “I can’t breathe”
the last words of Eric Garner who died in 2014 after he was put in a chokehold by an New York police officer
French rap may not always be explicit in its response to social unrest but it remains more political than its British or US cousins
Social media has made it easier for artists to access their audiences and engage with the stories that their fans are talking about
With increasing concerns for young people and ethnic minorities in France right now
it remains the only genre attempting to express what many voiceless people want to say
Photographs show a rhino interacting with a baby zebra
A photograph purportedly showing a rhinoceros lifting a zebra foal out of the mud has been circulating around the internet since at least February 2015
when it was shared by photographer Roel van Muiden of RvM Wildlife Photography
While the above-displayed photograph is frequently shared along with the claim that the rhino had saved the zebra foal
...it took me awhile to notice the tiny zebra foal stuck in the mud
The herd was nowhere in sight so the foal must have been there for quite some time
It's true that one of the rhinos attempted to lift the zebra from the mud
but this was most likely an act of curiosity
the rhino accidentally killed the foal during its investigation:
after being rebuffed by the cows numerous times
made his way down to the water and near to the muddy patch the foal was stuck in
The rhino started to prod the zebra with his horn out of curiosity
After a while he grew impatient and lifted the body out
The rhino lifted the foal so quickly that it had no time to react
The rhino then dropped the foal and moved off
He then came back for another prod and look-see
This time he lifted the zebra in a different position and his horn disemboweled the foal
the bull laid in the mud to roll around and almost crushed the baby zebra
While the above-displayed photographs are real
they do not depict the heartwarming story of a rhino rescuing a zebra — instead
they depict the less inspirational (but no less interesting) story of a hapless baby zebra accidentally killed by a curious rhino
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the people of the Marshall Islands check the walls that protect their homes from the sea
Sea levels in this part of the western Pacific are rising by 12mm a year—four times the global average—and countering them with sandbags
Eight islands in nearby Micronesia have been swallowed by the ocean in recent decades
and most of the Marshall Islands could follow by the end of the century
the apocalyptic consequences of climate change have become reality
Many people will be forced to find new places to live
suggests that there will be 200m environmental migrants by 2050
Both migrants fleeing environmental disaster and those escaping war will be constrained in their choices
But currently only the latter may seek refugee status
They make attacks on tanks more precise and troops easier to trap
Donald Trump’s desire for Greenland, and a shabby visit by his son, reignite the independence debate
The president-elect claims the crossing is controlled by China and rips off American consumers
How a miracle-working Greek bishop, Dutch folk figure and early New York icon became the ubiquitous symbol of Christmas
They were united against the country’s dictator. Now they have little in common
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The Delft students of the Vattenfall Solar Team, which will take part in the Solar Challenge Morocco in a month’s time, have announced that solar car Nuna11 has passed its first laps on Moroccan soil with flying colours. “Now the drivers need to get there as well.”
Out of the pit box, onto the Moulay El Hassan circuit: the first metres on Moroccan soil went well for Nuna11. (Photo: still from the test drive YouTube-video)
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ABC NewsHarvey Weinstein: The jokes we missed in 30 Rock
Entourage and from Seth McFarlaneShare Harvey Weinstein: The jokes we missed in 30 Rock
Entourage and from Seth McFarlaneTopic:Arts
Harvey Weinstein has produced or distributed a number of Oscar-winning movies
Link copiedShareShare articleFive years ago there was a line in an episode of 30 Rock that alluded to Harvey Weinstein having a reputation for asking actresses for sexual favours
It was a quick jab, buried in a wider plot line about show business, but is now being used as an example of how Weinstein's alleged behaviour has been an "open secret" in Hollywood for years
"I'm not afraid of anyone in show business," says actress Jenna Maroney
"I turned down intercourse with Harvey Weinstein on no less than three occasions … out of five."
And it's not the only reference to Weinstein's alleged behaviour that's been laughed off in the past
Take this joke made by comedian Seth McFarlane after announcing the 2012 Oscar nominees for best supporting actress:
And then there was the intimidating and aggressive "Harvey Weingard" played by Maury Chaykin in HBO's Entourage
a character widely believed to have been inspired by Weinstein
You're gonna beg to get back into the pizza business," Weingard yells in one scene
But even Judi Dench, who has had a running joke with Weinstein for years that she has a tattoo of his name on her bottom, says she was "completely unaware" of the alleged offences.
"Whilst there is no doubt that Harvey Weinstein has helped and championed my film career for the past 20 years, I was completely unaware of these offences which are, of course, horrifying and I offer my sympathy to those who have suffered, and wholehearted support to those who have spoken out," she said in a statement provided to Entertainment Weekly.
But Kate Winslet, who won an Oscar for The Weinstein Company's The Reader, appeared to confirm in her statement that there had been rumours about Weinstein for some time.
"I had hoped that these kind of stories were just made-up rumours, maybe we have all been naïve," she wrote.
Weinstein has apologised for causing "a lot of pain" with his behaviour in the past, but his spokeswoman Sallie Hofmeister says he denies "any allegations of non-consensual sex".
Topic:Food and Beverage Processing Industry
CNN and the BBC World Service which is copyright and cannot be reproduced
AEST = Australian Eastern Standard Time which is 10 hours ahead of GMT (Greenwich Mean Time)
An 18-year-old woman from Zaandam was stabbed multiple times in a car under the A1 viaduct with Muidertrekvaart in Muiden on Sunday morning. The police arrested a 21-year-old man from Amsterdam as a suspect
The victim was hospitalized with severe injuries
The Amsterdam man repeatedly stabbed the young woman in a stationary car under the A1 viaduct
“The victim managed to escape from the car
but the man chased her and assaulted her.”
Investigators would like to speak to that woman as a witness and ask her
First responders rushed the severely injured young woman to a nearby hospital for treatment
The police arrested the suspect near the incident a short time later
Netherlands: The stories behind the castlesBookmarkBookmarkBy William NehraJul 18, 2020I think it’s really important for us to remember our history. Not just the great, world-changing events like the World Wars or the Bubonic Plague but it’s important to remember local history. I guarantee you, wherever you are in the world, be it a sprawling city
you can find fascinating and oftentimes surprising stories that have been fallen into obscurity
Castles have been a point of interest for centuries
They have captured people’s imagination through their grandeur
Whether it be Count Dracula or Game of Thrones
castles have provided the setting for numerous stories
So today, with this in mind, we are going to delve into the history of two different castles in the Netherlands
dramatic and disturbing stories of all the castles in the Netherlands
Located at the mouth of the Vecht river, some 15 kilometres south-east of Amsterdam
Muiden Castle (Muiderslot) was built by Count Floris V in 1280
Floris was the Count of Holland and Zeeland from 1256 until his death in 1296
He ruled peacefully (for the most part) and is credited with modernizing administration
reclaiming land from the sea and generally acting in the interests of the common man
When King Edward I of England moved his wool trade from Dordrecht in Holland to Mechelen in Brabant in order to gain Flanders’s support against France
Floris decided to switch sides and ally with the French
This incensed the English King into ordering nobles
who had previously suffered at the hands of Floris
Gerard van Velsen and the lords of Amstel and Woerden
along with several other nobles attacked and kidnapped the Count while he was out hunting
He was taken back to Muiden Castle and kept there until the conspirators caught wind of a rescue attempt organised by the people
They attempted to leave the castle but were stopped by an angry mob
van Velsen rode back to the horse where Floris was bound and gagged and drew his sword
The Count fell to the ground and van Velsen stabbed him 22 times
he was unwilling for the Count to escape alive
as he rumour had it the Count had once raped van Velsen’s wife
either by being quartered or rolled down the street in a barrel lined with nails
The castle was demolished by the year 1300
It was rebuilt between 1370 and 1386 and eventually fell into the hands of the legendary Dutch author
who had taken on sheriff and bailiff duties in the area
Hooft spent his summers in the castle and invited great academics and artists such as Joost van der Vondel
Sir Constantijn Huygens and Gerbrand Bredero to his home
Here the castle saw the founding of the Muiderkring
a literary society for these esteemed academics and artists
Kasteel Waardenburg is another castle that hides secret and mysteries within its walls
The castle was built after Count Otto II of Guelders pledged the manor of Waardenburg in 1265 to a knight named Rudolph de Cock
the infamous Doctor Faust came to own the castle
Faust had recently met the Devil himself at a crossroads and
he made a pact with the Prince of Darkness
In exchange for worldly pleasures and an unlimited capacity for knowledge
Faust would give his soul to the Devil after seven years
black magic and dark experiments the Devil finally returned to claim what was his
He sneaked up on Faust and grabbed him by his hair and hauled him from the castle’s tower
Legend has it you can still see the bloodstains on the floor outside the tower to this day
Castle Waardenburg also has a lot of historical significance
where the old United Provinces (today’s Netherlands
Belgium and Luxembourg) under the leadership of William the Silent
The owner of the castle at the time sided with the Spanish
He laid siege to the castle and destroyed the south side and bailey were completely destroyed and never rebuilt
which explains why the castle is shaped like a horseshoe today
I hope you enjoyed these stories about Muiden Castle and Castle Waardenburg
I think it’s important to share these stories
as they reflect important parts of our history and in some cases
While some of these stories might not be entirely genuine (specifically the Doctor Faust story)
they are a reflection of people and their capacity to entertain through the medium of storytelling
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Wil je een dagje vergaderen in een bijzondere, inspirerende omgeving? Je hebt groot gelijk: ver van kantoor vind je groep de rust om nieuwe inzichten op te doen. En ‘ver van kantoor’ hoeft helemaal niet écht heel ver te zijn. In de directe omgeving van Amsterdam liggen diverse locaties in een omgeving die zowel verrassend is qua sfeer als qua bereikbaarheid. Wij bezoeken vijf inspirerende vergaderlocaties vlakbij Amsterdam!
Meld je nu aan en ontvang elke week het laatste locatienieuws.
Meld je aan voor onze LocatieFlash en mis nooit meer het laatste nieuws over nieuwe en gerestylede locaties.
Amazing Race Suomi -seikkailuohjelman avausjakso on juuri näyttänyt
että pienenkin maan budjetilla on mahdollista tuottaa kansainvälisten standardien mukainen
vauhdikas ja jännittävä Amazing Race -jakso.