Olympic medalists Maia And Alex Shibutani are set to make a competitive comeback after a seven-year hiatus
Two-time Olympic medalists Maia and Alex Shibutani have announced their return to competitive figure skating
They plan to compete in the upcoming 2025-26 Olympic season under the guidance of coaches Marina Zoueva and Massimo Scali
The Shibutani’s decorated career includes two U.S
2017) and three World Championships medals (2011
At the 2018 Olympic Winter Games in PyeongChang
they won bronze medals in the ice dance and the team event competitions
making history as the first athletes of Asian descent and only non-white team to earn an Olympic ice dance medal
the Shibutanis took a break from competition
which they extended following Maia’s kidney cancer diagnosis in 2019
During their time away from competitive skating
the Shibutanis have expanded their horizons as authors of four children’s books while continuing to contribute to the sports world as choreographers
ambassadors and advocates for diversity and representation
“These past seven years have challenged and inspired us in ways we never expected
I’m so happy and grateful to be healthy and in a position to make the decision to return to the sport I love in this way,” Maia said
“Our experiences and the new skills we’ve developed during our time away from competition have brought us different perspectives and created some exciting new possibilities
We're really enjoying the process and look forward to performing and competing together again,” said Alex
The siblings began their partnership in 2004 and have earned medals in each of their 14 U.S
the Shibutanis made their debut at the ISU World Figure Skating Championships and became the youngest ice dance team in nearly 50 years to reach the podium
Figure Skating Hall of Fame in their first year of eligibility for their achievements and contributions to the sport
it’s incredibly exciting to have Maia and Alex return to competition next season,” said Justin Dillon
Figure Skating senior director of athlete high performance
“They are strong ambassadors for the sport
Their comeback adds to the excitement surrounding Team USA after a very successful year and makes the team stronger as we look toward the Olympic season.”
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the 2018 Olympic bronze medalists in ice dance and figure skating’s team event
plan to return to competition for the first time in seven years for the 2025-26 Olympic season
They made the announcement in a social media post and video
“Our experiences and the new skills we’ve developed during our time away from competition have brought us different perspectives and created some exciting new possibilities,” Alex said in a press release
We’re really enjoying the process and look forward to performing and competing together again.”
last competed at the 2018 PyeongChang Games
The Shibutanis won their first world medal (bronze) in their senior debut season in 2010-11 as the youngest medalists in the event in nearly 50 years
They later won both national titles and world championships medals in 2016 (silver) and 2017 (bronze)
they became the second set of siblings to earn Olympic ice dance medals after France’s Isabelle and Paul Duchesnay in 1992
They were also the first ice dancers of Asian descent to earn Olympic ice dance medals
Maia announced that she had a cancerous kidney tumor removed and that she had SDH-deficient renal cell carcinoma
and no further treatment was required at the time
“These past seven years have challenged and inspired us in ways we never expected,” Maia said in Thursday’s release
“I’m so happy and grateful to be healthy and in a position to make the decision to return to the sport I love in this way.”
the Shibutanis wrote four children’s books
they will be coached by Marina Zoueva and Massimo Scali
Zoueva coached them from 2007 through the 2018 Olympics
They worked with Scali as a choreographer in the 2018 Olympic cycle
Figure Skating committee will select the three ice dance couples after next January’s U.S
taking into account results over the previous year
Americans Madison Chock and Evan Bates won their third consecutive world ice dance title
Christina Carreira and Anthony Ponomarenko
plus made the podium in both of their fall Grand Prix starts for the first time
is pursuing citizenship to become eligible to represent the U.S
bronze medalists Caroline Green and Michael Parsons placed ninth at worlds
The 2025-26 figure skating season begins in earnest in September
The top-level Grand Prix Series starts in October
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The Shibutani siblings won bronze in the 2018 Winter Olympics before Maia was diagnosed with cancer in 2019
Maia and Alex Shibutani are making a stunning return to competitive figure skating
"Our experiences and the new skills we’ve developed during our time away from competition have brought us different perspectives and created some exciting new possibilities," Alex Shibutani said in a news release
We're really enjoying the process and look forward to performing and competing together again."
The Shibutani siblings are among the most prominent ice dancing teams in U.S
After making their senior world championships debut in 2011
two national titles and two Olympic medals − in the ice dance and team events at the 2018 Games
While the Shibutanis never formally announced their retirement, they were thought to be done after the 2018 Winter Olympics. Following those Games, they declined to compete at the 2018 world championships and said they would be taking a year off
Maia Shibutani then had surgery in late 2019 to remove a tumor from one of her kidneys
the siblings began to shift their focus to other endeavors
writing four children's books and trying new roles in choreography
"These past seven years have challenged and inspired us in ways we never expected," Maia Shibutani said in a statement
"I’m so happy and grateful to be healthy and in a position to make the decision to return to the sport I love in this way."
The Shibutanis announced they will be training with two of their longtime coaches
Marina Zoueva and Massimo Scali − presumably with hopes of making it back to the Olympic Games for a third time
They finished ninth at the 2014 Sochi Games
The "Shib Sibs" will join a competitive U.S. ice dancing field that had one of its best ever performances at the most recent world figure skating championships in Boston, led by Madison Chock and Evan Bates, who won their third consecutive title
Christina Carreira and Anthony Ponomarenko finished just off the podium in fifth
followed by Caroline Green and Michael Parsons in ninth
Contact Tom Schad at tschad@usatoday.com or on social media @tomschad.bsky.social
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by Chris Murray
Maia Rosarion was one of the top freshmen in the Ohio Valley Conference last season with the 5-foot-10 forward averaging 5.9 points and 5.2 rebounds in just 15.7 minutes per game for Morehead State as a rookie
The Vancouver native is transferred to Nevada for next season
We caught up with Rosarion to discuss her move to the Wolf Pack
FALMOUTH — Maia Ledwell knows to bring an aggressive mindset to her tennis game
Falmouth (4-6) coach Kara Berger said that earlier in Ledwell's career
What has stayed consistent for Ledwell is an attitude for growth
and the junior captain is really coming into her own
In Thursday's 5-0 win over Dennis-Yarmouth (1-8)
Ledwell's best trait is her demeanor on the court
and you can tell if they're winning or losing
That points to Ledwell's leadership and ability to set an example for her teammates
She did shift her play to rein in the aggressiveness when needed
"I kind of adjust to the person I'm playing against," Ledwell said
I'll try to counteract it by just getting the ball over
but she already has some ideas in mind for college
She hopes to play either Division 3 college tennis
or perhaps club tennis for a Division 1 program
she will be prepared for that choice when it is time to make it
"I definitely want to stay local," Ledwell said
Her coach and teammates would say Ledwell is pretty awesome
it can be difficult to keep a positive attitude
2 singles player for the Dolphins and a junior captain
When the losing gets in the way of the high school tennis experience
"I feel like I have to (lift the spirits sometimes)
That's something that I'm really trying harder on
Gurung lost her match to Falmouth's Genevieve Maranchie
D-Y coach Joseph Downes has loved what he has seen from Gurung this season
and considers her one of the team's best players
"She's just improved every day," Downes said
It might not show in the scorecard in the end
One way Gurung did that was organizing a bake sale
especially because last year we only had 11 people
"One of the things I really wanted to incorporate this year was the money
and being able to get supplies and sweatshirts for fun
All that has been a way of recruiting new players to the team
Adam Kurkjian covers high school sports for the Cape Cod Times. You can contact him at akurkjian@gannett.com and follow him on X at @AdamKurkjian
Thanks to our subscribers, who help make this coverage possible. If you are not a subscriber, please consider supporting quality local journalism with a Cape Cod Times subscription. Here are our subscription plans
As part of the ongoing Mutua Madrid Open, WTA stars Ons Jabeur, Camila Osorio, Demi Schuurs, Luisa Stefani and Beatriz Haddad Maia paid a visit to Real Madrid City this week.
The players were welcomed by members of the Real Madrid women’s team -- Athenea del Castillo, Caroline Weir, Rikke Møller Jensen, Linda Caicedo and Antonia Silva -- ahead of a training session.
The two groups exchanged gifts and shared a moment to celebrate the crossover between football and tennis during one of the sport’s biggest combined events. Highlights from the visit are below.
The 2025 Mutua Madrid Open runs through May 4 at the Caja Magica.
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View this post on Instagram A post shared by WTA (@wta)
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Maia Bingham Boggess (BIO ‘25) discovered that the possibilities are endless at BYU
She participated in multiple experiential learning experiences
including working with insects at the Monte L
Bean Life Science Museum and studying microorganisms from Antarctica in Dr
She also completed a dermatology internship
spent a semester studying abroad in Ghana with Dr
and is now working as a medical assistant for Apple
each new opportunity reflected the adaptable nature of her education and her drive to make the most of wherever life took her
Deeply impacted by her study abroad in Ghana under the mentorship of Dr
Boggess engaged in humanitarian work and biological fieldwork
But what left the biggest impression was the bond she formed with Belk and his wife
“He wasn’t just someone assigning me a grade,” she said
and I cared about theirs.” That experience taught her the power of relationships and the value of serving together
The relationships she formed at BYU became essential in helping her navigate an unexpected change
she worked with her professors and academic advisors to complete the remainder of her courses
Boggess was able to remain connected to BYU thanks to strong support from Belk
Belk and his wife have shown Boggess how meaningful and personal mentorship at BYU can be
Boggess’ experiences strengthened her faith and ability to rely on God
"I've always had a plan in my head of what my life should be
My undergrad and mission experiences have taught me that God's plan is better than my plan
His plan might not be the most comfortable
but the result will be better than I could have imagined," Boggess said
It’s a mindset that helps her approach new opportunities with trust
and an openness to whatever God has in store
Boggess continues to live BYU’s motto to “Go forth to serve.” She volunteers with her husband
at a soccer program for children with disabilities and hopes to serve Spanish-speaking communities in the future
thanks in part to her medical Spanish classes at BYU
“Those small community interactions are what fulfill me,” she said
Christ teaches us to minister to the one—to meet the people around us and serve them.” With plans to apply to PA school in Colorado
Boggess feels ready for whatever comes next
College of Life SciencesLife Sciences Building (LSB)Provo
Utah 84602-Dean's Suite: 801-422-1458Advisement Center: 801-422-3042
the year after countryman Gustavo Kuerten turned professional -- and the year before he lit up Paris by winning his first title at Roland Garros
“Guga” Kuerten would be crowned French Open champion three times in five years
memorably carving a heart in the red clay on the way to his final win in 2001
“All of us in Brazil, we grew up hearing about Roland Garros, hearing about Guga and the wins,” Haddad Maia told wtatennis.com on Monday from the Porsche Tennis Grand Prix in Stuttgart. “Most of the courts that we have are clay courts and we are more used to playing on this surface.
“I really like to play on clay. The ball bounces a little bit more. We have rallies. I can also play as a lefty. It’s a very big moment of the year that I can improve my game.”
She’ll be tested immediately Tuesday in Stuttgart with a featured night match against No. 7 seed Emma Navarro. How loaded is this field? That’s two Top 20 players going at it in a first-round match.
Haddad Maia, 30-25 for her career on clay, is hoping two months on European clay bring back the confidence that carried her so far last fall. Haddad Maia, 28, was a finalist in Cleveland, a quarterfinalist at the US Open and a champion at the WTA 500 event in Seoul, winning 12 of 14 matches in that span.
However, after advancing to the third round at the Australian Open in January, it’s been an ongoing struggle this year. Working hard, Haddad Maia insisted, is always the solution.
“There have been moments when I wasn’t playing my best tennis,” she said. “For me, the key was always to work hard, keep in the present, have a positive mentality as I have during my career.
“The mentality to try to be tough. Try to be myself. Controlling the things that I can control and not thinking to control things I can’t. I’m not like a genius person. I know that I need to work very hard to create opportunities.”
That’s precisely what happened in 2023, when Haddad Maia put together a remarkable run on red clay. After reaching the quarterfinals in Stuttgart, she matched that result in Rome -- and then crashed into the semifinals at Roland Garros. It was her best Grand Slam result to date.
View this post on Instagram A post shared by Beatriz Haddad Maia (@biahaddadmaia)
Haddad Maia got to the quarters in Madrid -- beating Navarro along the way -- before losing a three-set match to Iga Swiatek
Haddad Maia leads Navarro 2-1 in their head-to-head
and both of the Brazilian's wins came in the span of one month on red clay
There shouldn’t be any great surprises on Tuesday; Haddad Maia and Navarro sometimes practice together
She came from college and it’s nice to see girls improving and pushing the level up
“I will try to work very hard to bring my game and let’s see if it works again.”
17 in the PIF WTA Rankings and her goal is to crack the Top 10 as she did two years ago after that final four appearance in Paris -- and stay healthy
it’s a very different game,” Haddad Maia said
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Metrics details
daratumumab plus lenalidomide and dexamethasone (D-Rd) improved progression-free survival (PFS) and overall survival (OS) versus lenalidomide and dexamethasone (Rd) alone in transplant-ineligible patients with newly diagnosed multiple myeloma (NDMM)
We report updated efficacy and safety from MAIA (median follow-up
including a subgroup analysis by patient age (<70
737 transplant-ineligible patients with NDMM were randomized 1:1 to D-Rd or Rd
Median OS was not reached in the D-Rd group versus 65.5 months in the Rd group (HR
0.53–0.83; P = 0.0003); estimated 60-month OS rates were 66.6% and 53.6%
D-Rd achieved higher rates of complete response or better (≥CR; 51.1% vs 30.1%)
minimal residual disease (MRD) negativity (32.1% vs 11.1%)
and sustained MRD negativity (≥18 months: 16.8% vs 3.3%) versus Rd (all P < 0.0001)
D-Rd demonstrated clinically meaningful efficacy benefits across age groups
>5 years) continue to support frontline use of D-Rd in transplant-ineligible patients with NDMM
we report results from an updated analysis of the efficacy and safety in MAIA at a median follow-up of 64.5 months
which was the final longest follow-up of the MAIA trial that comprised a complete dataset
We also report results from a subgroup analysis of patients from MAIA based on age (<70 years
an Eastern Cooperative Oncology Group performance status of 0 to 2
and were ineligible for high-dose chemotherapy with autologous stem cell transplant because of age (≥65 years) or comorbidities
The independent ethics committee or institutional review board approved the protocol at each site (Supplementary Table 1)
All methods were performed in accordance with the relevant guidelines and regulations
The trial was conducted in accordance with the principles of the Declaration of Helsinki and the International Conference on Harmonisation Good Clinical Practice guidelines
All patients provided written informed consent
Patients were randomly assigned 1:1 to treatment with D-Rd or Rd and were stratified by International Staging System disease stage (I vs II vs III)
geographic region (North America vs other)
All patients received 28-day cycles of oral lenalidomide (25 mg [10 mg if the patient’s creatinine clearance was 30–50 mL/min] on Days 1–21) and oral dexamethasone (40 mg [20 mg if the patient was aged >75 years or had a body mass index <18.5 kg/m2] on Days 1
and 22) until disease progression or unacceptable toxicity
Patients in the D-Rd group also received intravenous daratumumab 16 mg/kg once weekly during Cycles 1 and 2
and 60 months after the first dose] in patients with a near ≥CR) using bone marrow aspirate samples and was evaluated via next-generation sequencing using the clonoSEQ® assay (v.2.0; Adaptive Biotechnologies
PFS on next line of therapy was defined as the time from randomization to progression on next line of therapy or death
Patients were censored at the last disease assessment before starting their next line of therapy if they did not show disease progression on study treatment
Patients who started their next line of therapy after progressing on study treatment
and had not yet progressed on next line of therapy were censored on the last date of follow-up
Patients without post-baseline follow-up were censored at randomization
The primary analysis was performed in the intent-to-treat (ITT) population
which included all patients who underwent randomization
PFS and OS were compared between treatment groups using a log-rank test stratified with randomization stratification factors
The Kaplan–Meier method was used to estimate distributions; HRs and 95% CIs were estimated using a Cox regression model
with treatment as the sole explanatory variable and stratified with randomization stratification factors
Response rates were compared between treatment groups using the Cochran–Mantel–Haenszel chi-square test
and response rates were analyzed similarly to the overall ITT population
but randomization stratification factors were excluded
MRD-negativity rates were compared between treatment groups using the Fisher’s exact test
Nominal P-values were calculated for all analyses reported herein
Safety analyses were performed in the safety population
which included all randomized patients who received ≥1 dose of study treatment
All authors had full access to all of the data in the study and had responsibility for the decision to submit for publication
The data sharing policy of Janssen Pharmaceutical Companies of Johnson & Johnson is available at https://www.janssen.com/clinical-trials/transparency. As noted on this site, requests for access to the study data can be submitted through Yale Open Data Access (YODA) Project site at http://yoda.yale.edu
Kaplan–Meier estimates of (A) PFS and (B) OS in the ITT population. PFS progression-free survival, OS overall survival, ITT intent-to-treat, D-Rd daratumumab plus lenalidomide/dexamethasone, Rd lenalidomide/dexamethasone, HR hazard ratio, CI confidence interval, NR not reached.
Kaplan–Meier estimates of (A) PFS in patients aged <70 years
and ≥75 years; (B) PFS in patients aged ≥80 years; (C) OS in patients aged <70 years
and ≥75 years; and (D) OS in patients aged ≥80 years
D-Rd daratumumab plus lenalidomide/dexamethasone
A total of 52 patients in the D-Rd group discontinued lenalidomide ± dexamethasone and remained on the rest of study treatment at clinical cutoff; 46 (88.5%) patients discontinued due to AEs (Supplementary Table 5)
Among these 52 patients in the D-Rd arm who discontinued only lenalidomide ± dexamethasone
the median time to lenalidomide discontinuation was 37.8 months (range
and median daratumumab treatment duration was 66.2 months (range
Estimated 60-month PFS and OS rates for the 52 patients in the D-Rd arm who discontinued lenalidomide ± dexamethasone but continued remaining treatment were 98.1% and 100.0%
Thirteen (25.0%) of the 52 patients discontinued lenalidomide and continued on daratumumab + dexamethasone
and 39 (75.0%) of the 52 patients discontinued lenalidomide + dexamethasone and continued on daratumumab monotherapy
Among the 39 patients who discontinued lenalidomide + dexamethasone and continued on daratumumab monotherapy
median time to lenalidomide + dexamethasone discontinuation was 39.1 months (range
and median daratumumab treatment duration was 65.6 months (range
Estimated 60-month PFS and OS rates for the 39 patients in the D-Rd arm who discontinued lenalidomide +dexamethasone but continued on daratumumab monotherapy were 97.4% and 100.0%
One patient in the D-Rd group discontinued daratumumab but remained on lenalidomide treatment at clinical cutoff; the patient discontinued daratumumab after 15 days of treatment due to AEs
The patient had not progressed at the time of clinical cutoff
A Cumulative ≥CR and (B) MRD-negativity rates by 12, 18, 24, 30, 36, 48, and 60 months in the ITT population. CR complete response, MRD minimal residual disease, ITT intent-to-treat, D-Rd daratumumab plus lenalidomide/dexamethasone, Rd lenalidomide/dexamethasone.
128 (35.2%) patients in the D-Rd arm and 194 (53.2%) patients in the Rd arm had received subsequent therapy
Among those who received subsequent therapy
9.4% of patients in the D-Rd arm and 23.2% of patients in the Rd arm received a daratumumab-containing treatment as their first subsequent therapy
received a daratumumab-containing treatment in any subsequent line of therapy
PFS on next line of therapy was 73.7 months in the D-Rd arm versus 48.9 months in the Rd arm (HR
No new safety concerns were observed with longer follow-up (Table 3)
Grade 3/4 treatment-emergent AEs (TEAEs) were reported in 95.9% of patients in the D-Rd arm and 88.8% of patients in the Rd arm
The most common (≥20%) grade 3/4 TEAEs with D-Rd versus Rd were neutropenia (54.1% vs 37.0%) and anemia (17.0% vs 21.6%)
Grade 3/4 infection rates were 42.6% with D-Rd and 29.6% with Rd
Serious TEAEs were reported in 78.8% of patients in the D-Rd arm and 71.0% of patients in the Rd arm
with pneumonia being the most common serious TEAE (18.7% and 10.7%
Overall rate of study treatment discontinuation due to TEAEs was lower with D-Rd versus Rd (14.6% vs 23.8%
TEAEs led to discontinuation of lenalidomide in 36.8% of patients in the D-Rd arm and 24.4% of patients in the Rd arm
and TEAEs led to discontinuation of dexamethasone in 39.8% of patients in the D-Rd arm and 36.2% of patients in the Rd arm
Rate of daratumumab discontinuation due to TEAEs was 14.6%
TEAEs with an outcome of death occurred in 9.9% of patients in the D-Rd arm and 9.3% of patients in the Rd arm
Grade 3/4 TEAEs occurred in 95.5% of patients in the D-Rd arm and 95.0% of those in the Rd arm who were aged ≥75 years and in 92.3% and 95.7%, respectively, who were aged ≥80 years. Rates of common grade 3/4 TEAEs in patients aged ≥75 years and ≥80 years were generally similar to those of the overall study population (Supplementary Table 6)
serious TEAEs occurred in 80.9% of patients in the D-Rd arm and 79.2% of those in the Rd arm
the most common of which was pneumonia (19.7% and 12.6%
TEAEs led to study treatment discontinuation in 15.3% of patients in the D-Rd arm and 27.7% of those in the Rd arm
and TEAEs with an outcome of death occurred in 11.5% and 13.2% of patients
serious TEAEs occurred in 81.5% of patients in the D-Rd arm and 82.9% of those in the Rd arm
with pneumonia being most common (24.6% and 8.6%
TEAEs led to study treatment discontinuation in 6.2% of patients in the D-Rd arm and 20.0% of those in the Rd arm
and TEAEs with an outcome of death occurred in 12.3% and 11.4% of patients
which demonstrated statistically significant and clinically meaningful improvement in PFS and OS with D-Rd versus Rd treatment until disease progression in transplant-ineligible patients with NDMM
Treatment with D-Rd resulted in a 45% reduction in the risk of disease progression or death versus Rd
a 34% reduction in the risk of death was observed with D-Rd
These clinically meaningful improvements are particularly noteworthy given the lower median relative dose intensity of lenalidomide in the D-Rd arm
PFS and OS benefits with D-Rd versus Rd were generally consistent across prespecified patient subgroups
Deepening of response continued over time for patients who remained on D-Rd treatment
as best response of ≥CR rates with D-Rd more than tripled from 6 months (8.2%) to 12 months (28.0%) and continued to increase with continued therapy up to 51.1% by 48 months
Patients who achieved a best response of ≥CR had higher 60-month PFS rates (73.7% with D-Rd vs 53.8% with Rd) and 60-month OS rates (81.7% with D-Rd vs 69.1% with Rd) than patients who achieved a best response of VGPR (37.1% vs 23.2% and 61.5% vs 53.0%
D-Rd also achieved a nearly 2-fold higher MRD-negativity rate and >3-fold higher sustained MRD-negativity rates lasting ≥12 and ≥18 months versus Rd alone
MRD-negativity rates also increased over time with continued D-Rd treatment
more than doubling from 12 months (12.8%) to 60 months (31.8%)
Patients who achieved MRD negativity had improved PFS and OS versus those who were MRD positive
patients who continued on D-Rd therapy had an increased likelihood of achieving deeper responses
translating to improved long-term outcomes
Results from a subgroup analysis of patients from MAIA based on age (<70
and ≥80 years) were consistent with those reported for the ITT population
D-Rd demonstrated a meaningful benefit versus Rd in clinically relevant endpoints
D-Rd induced higher rates of deep responses versus Rd across all age subgroups evaluated
No new safety concerns were observed with longer follow-up
While the rates of grade 3/4 TEAEs and serious TEAEs were higher with D-Rd versus Rd
the rate of study treatment discontinuation due to TEAEs was lower with D-Rd versus Rd
the latter of which may primarily be attributable to the MAIA study design
lenalidomide discontinuation was categorized as overall study treatment discontinuation
overall study treatment discontinuation required discontinuation of both daratumumab and lenalidomide
In subgroup analyses of safety in patients aged ≥75 and ≥80 years
the rates of grade 3/4 TEAEs and serious TEAEs were similar for D-Rd and Rd
and the rate of study treatment discontinuation due to TEAEs was lower for D-Rd versus Rd
patients in MAIA received D-Rd triplet therapy until disease progression
whereas patients in SWOG S0777 received 8 cycles of VRd triplet therapy followed by Rd until disease progression
suggest that MRD status may serve as a more accurate prognostic indicator for clinical outcomes than relying on hematologic response rates (ie
As MRD negativity may serve as a more robust measure of disease control if it is sustained over time
sustained MRD negativity lasting ≥6 months
and beyond may represent yet an even deeper response with a greater prognostic value
A limitation of this study is that the results focus on outcomes of patients treated with D-Rd versus Rd in their first line of therapy
Among patients in the Rd group who received subsequent therapy
23% of patients received a daratumumab-containing regimen as first subsequent therapy and 49% received a daratumumab-containing regimen as any subsequent line of therapy
the D-Rd group demonstrated a significant survival advantage over the Rd group
underscoring the importance of using D-Rd as first-line treatment in this setting and identifying potential barriers to accessing treatment
shaped by factors such as patient location
might have led to fewer patients receiving a daratumumab-based regimen as subsequent therapy
a novel therapeutic human CD38 monoclonal antibody
induces killing of multiple myeloma and other hematological tumors
Direct in vitro comparison of daratumumab with surrogate analogs of CD38 antibodies MOR03087
Antibody-mediated phagocytosis contributes to the anti-tumor activity of the therapeutic antibody daratumumab in lymphoma and multiple myeloma
The therapeutic CD38 monoclonal antibody daratumumab induces programmed cell death via Fcγ receptor-mediated cross-linking
Daratumumab depletes CD38+ immune-regulatory cells
and skews T-cell repertoire in multiple myeloma
High-parameter mass cytometry evaluation of relapsed/refractory multiple myeloma patients treated with daratumumab demonstrates immune modulation as a novel mechanism of action
Deep immune profiling of patients treated with lenalidomide and dexamethasone with or without daratumumab
Comparison of CD38 antibodies in vitro and ex vivo mechanisms of action in multiple myeloma
DARZALEX® (daratumumab) injection [package insert]
and dexamethasone in previously treated multiple myeloma (POLLUX): a randomized
and dexamethasone in previously treated multiple myeloma (CASTOR): a randomized
and dexamethasone versus lenalidomide and dexamethasone alone in newly diagnosed multiple myeloma (MAIA): overall survival results from a randomised
and prednisone in newly diagnosed multiple myeloma (ALCYONE): a randomised
Daratumumab plus lenalidomide and dexamethasone for untreated myeloma
Sustained minimal residual disease negativity in newly diagnosed multiple myeloma and the impact of daratumumab in MAIA and ALCYONE
Final survival analysis of daratumumab plus lenalidomide and dexamethasone versus lenalidomide and dexamethasone in transplant-ineligible patients with newly diagnosed multiple myeloma: MAIA Study
Presented at: the 2024 European Hematology Association (EHA) Hybrid Congress
Consensus recommendations for the uniform reporting of clinical trials: report of the International Myeloma Workshop Consensus Panel 1
International uniform response criteria for multiple myeloma
Lenalidomide and dexamethasone in transplant-ineligible patients with myeloma
Benefit of continuous treatment for responders with newly diagnosed multiple myeloma in the randomized FIRST trial
Daratumumab improves depth of response and progression-free survival in transplant-ineligible
Longer term follow-up of the randomized phase III trial SWOG S0777: bortezomib
lenalidomide and dexamethasone in patients (Pts) with previously untreated multiple myeloma without an intent for immediate autologous stem cell transplant (ASCT)
Bortezomib with lenalidomide and dexamethasone versus lenalidomide and dexamethasone alone in patients with newly diagnosed myeloma without intent for immediate autologous stem-cell transplant (SWOG S0777): a randomised
Maintenance with daratumumab or observation following treatment with bortezomib
and dexamethasone with or without daratumumab and autologous stem-cell transplant in patients with newly diagnosed multiple myeloma (CASSIOPEIA): an open-label
Download references
This study (ClinicalTrials.gov Identifier: NCT02252172) was sponsored by Janssen Research & Development
We thank the patients who participated in the study and their families
and coordinators at each of the clinical sites
Medical writing and editorial support were provided by Lisa Shannon
and were funded by Janssen Global Services
Hematology and Bone Marrow Transplantation with Section of Pneumology
University Medical Center Hamburg-Eppendorf
GMMG-Study Group at University Hospital Heidelberg
Vejle Hospital and University of Southern Denmark
The University of Texas MD Anderson Cancer Center
Arnie Charbonneau Cancer Research Institute
Royal Wolverhampton NHS Trust and University of Wolverhampton
Massachusetts General Hospital Cancer Center
Centre Hospitalier Universitaire (CHU) de Caen
Leeds Institute of Clinical Trials Research
and SKK contributed to the study conception and/or design; TF
and SKK contributed to data acquisition; TF
and SKK contributed to data analysis; and TF
and SKK contributed to data interpretation
All authors participated in drafting and revising the manuscript and approved the final version before submission
PM served on an advisory board for and received honoraria from Janssen
and Takeda; received honoraria from AbbVie
and Takeda; and received travel support from Janssen
HG received grants and/or provisions of Investigational Medicinal Product from Amgen
and Sanofi; received research support from Amgen
and Novartis; served on an advisory board for Amgen
and Adaptive Biotechnologies; received honoraria from Amgen
and Pfizer; and received support for attending meetings and/or travel from Amgen
and Takeda; served in a consulting role for AbbVie
and TeneoBio; and served on a speakers bureau for Amgen
AC served in a consulting role or on an advisory board for AbbVie
and Millennium/Takeda; and received research funding from Amgen
and AbbVie; and received research support from Janssen
RZO received research funding from Asylia Therapeutics
and Takeda; received honoraria from and served as a member on a board of directors or advisory committee for AbbVie
and Takeda; and holds stock in Asylia Therapeutics
NB served in a consulting or advisory role for and received honoraria from AbbVie
and Takeda; and received research funding from Pfizer and Celgene
SB served as a consultant and on a speakers bureau for Sanofi
HQ served as a consultant for and received research funding from AbbVie
and Takeda; served as a member on a board or advisory committee for Amgen
and Takeda; and received research funding from Takeda
CJ served as a member on a board or advisory committee for Amgen and GSK
NR served as a consultant for Bristol Myers Squibb
and GSK; and received research funding from bluebird bio
MM served on an advisory board for Celgene/Bristol Myers Squibb
and Sanofi; received research funding from Janssen and Takeda; and received accommodations from Janssen
and Takeda; and received funding from Janssen and Amgen
GC received research support from Bristol Myers Squibb/Celgene
and Takeda; and served as a consultant for and received honoraria from Amgen
and FB are employees of Janssen and hold stock in Johnson & Johnson
SKK has received research funding from AbbVie
and Molecular Templates; participated in consulting or an advisory board (with no personal payments) for AbbVie
and Arcellx; and participated in consulting or an advisory board (with personal payments) for Oncopeptides
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Melissa Joseph So you’ve been working on this show for over a year
Some people have it planned out and then execute; others are messier
figuring out what it means on the other end
I look at this space first and try to visualize the form of the show
I love that the first works to get started are sometimes the last works to get finished
And I always feel that the last piece is the thing I want to keep working on after the show
MJ That seems like a natural way for one thing to feed into the next so that you don’t get the post-show blues
MJ Your paintings have been increasing in scale for quite some time
Is the diptych in the show the biggest work you’ve done
Some of the pieces have—I’m not sure if I would call it a doubling—but almost a sense of linear time
MCP You know those old stereo cards where you need a viewer to look at them
There are two of the same image next to each other
and when you put them in the viewer it creates a triangle and becomes 3D
although it wasn’t actually over and under; it’s just next to
It’s also this idea of a line being inscribed
It really struck me when I read an essay by Patrick Rosales talking about the Philippine–American War and US imperialism as a horizon line spreading west and obliterating everything it comes in contact with
When it reached the Philippines that was the intention
but for Filipinos there was no such thing as a line
The content of the work is a mix of oral and personal histories and archival materials
MJ Just hearing the word inscribed immediately makes sense
The painting makes us question the veracity of our vision
actually describes perfectly how I’ve been feeling about things in a world that I used to see as a solid image but now seems to be dissolving and fracturing
I really appreciate that the image isn’t gone
MCP That’s the first one where I did the cutting
It’s something that I think about a lot in the work: losing your way and then finding it again
the image of the figures in that painting and in the diptych is these dancers
that painting is my mom when she passed away
and she was dancing with my dad on the dance floor
They were performing in front of all of their friends
that was a very personal painting to me just because I was there
and it was a total seismic shift in my life
MJ Were you already on the path of being an artist
but that wasn’t something that my mom was psyched about
but it’s so hard when we’re young and don’t know how much suffering is embedded into the human condition
I just ditched all my classes and went to art class
MJ I’m so glad you had that outlet and it brought you here
Can you share a bit about the piece with the wooden tree roots
MCP This was an idea I’ve had for a long time and was able to make it happen through this show
MCP The painting is based on a holy pilgrimage site in the Philippines
A theme in the show is questioning the act of looking
Melding the 3D and the 2D has been something I’ve been trying to conceive of for a while
was the first thing that my gay Filipino Auntie gave me
She’s been teaching me all about Filipino spirituality and told me that I have to go to Mount Banahaw
we had to enter into this deep crevice inside of these rocks to get down to this little sliver of healing spring water
The whole idea of that trip was that you go to these sites on the mountain
You do difficult physical acts to get to these places
we signed our names with the backs of our candles onto the cave wall
It’s a way to introduce yourself to the mountain
The names of everybody we went with are written on that painting
Are the animals part of the same spiritual conversation
MCP Dogs have been in the work from the beginning
There’s a couple of different layers to the dogs
aside from me just trying to convince Kim that we need to get a dog
MCP One of my first memories of the Philippines was of all the dogs that were there
I think about that a lot and what it is that we can’t see
They also refer to the St Louis World’s Fair in 1906
when Filipinos were brought and displayed at the fair
They were made to sacrifice and eat a dog every day
but was propaganda to show their perceived savagery
which would justify why America had conquered the Philippines and how they were doing a benevolent assimilation
MJ So are you placing them to confront people
MCP Every time I went to my grandmother’s house in the Philippines
That’s what I was imagining for the larger dog that’s standing on the floor
MJ And do you make collage studies before the paintings
MCP That’s how I’ve learned how to work with archival materials
When I started cutting things up and collaging
it felt like a way to open up the images and mix them all together
My reaction when I first went to research the archives was that it felt stiff and fixed for a reason
There was a US-imperialist message being pushed through these images
My way of countering that was to rip it apart and put it back together in a multiplicity of ways
MCP Getting to share the work has been the biggest gift of all
Openings and exhibitions are celebrations and gathering points where connections are made interpersonally and conversations prompted by the work are exchanged
Just like the magic of the stereoscopic 3D viewer
the gallery becomes a space where visitors become activated by artwork
and a new space has the potential to open up in our imaginations and psyche
Maia Cruz Palileo: SATOR ROTAS is on view at David Kordansky Gallery in Los Angeles until April 26
Melissa Joseph is a Brooklyn-based artist interested in connecting people through shared memories and experiences
The Nevada women's basketball team added its second transfer player in as many days after announcing Tuesday the addition of Morehead State's Maia Rosarion
Rosarion will held bolster the Wolf Pack's frontcourt after a strong rookie season in the Ohio Valley Conference
Rosarion averaged 5.9 points and 5.2 rebounds in just 15.7 minutes per game for the Eagles
She shot 55.9 percent from the field and made 58.1 percent of her free throws
Rosarion played in 29 games with nine starts
upping her averages to 7.6 points and 7.0 rebounds with 1.1 blocks in conference games
She has three years of college eligibility remaining
Rosarion played for Kitsilano Secondary School where she was a two-year varsity starter who mostly played on the wing
should will bolster a front line that last season was thin after injuries to Amelia Raidaveta and Olivia Poulivaati
perform at the 2018 Winter Olympics in Gangneung
(AP) — The Shib Sibs are making a comeback with an eye on more Olympic figure skating medals
The popular brother-sister ice dance team of Alex and Maia Shibutani announced Thursday they will return to competition this season in hopes of making the loaded American squad for the next year’s Milan-Cortina Games
The Shibutanis stepped away from competition after those Olympics
choosing to focus on school and other interests
They have authored four children’s books and worked as choreographers and ambassadors for diversity and representation
They extended their hiatus when Maia Shibutani was diagnosed with a malignant tumor on her kidney in 2019
and additional treatment resulted in a long
“These past seven years have challenged and inspired us in ways we never expected,” Maia Shibutani said
The Shibutanis continued to skate in exhibitions over the years, and they remained close to the Olympic movement, albeit in a different way. Last summer, Alex Shibutani worked as a photographer and Maia Shibutani did media work at the Paris Olympics, where U.S. figure skaters were finally awarded their team gold medals from the 2022 Beijing Games.
Alex Shibutani also is a member of the athletes’ commission for the organizing committee for the 2028 Los Angeles Games.
Now, the Shibutanis hope to be on the next American squad headed to the Olympics.
They will be training with longtime coach Marina Zoueva and Massimo Scali, who recently helped Alysa Liu return from her own brief retirement to win the first women’s world title for a U.S. figure skater in nearly two decades.
“As Olympic medalists and U.S. Figure Skating hall-of-famers, it’s incredibly exciting to have Maia and Alex return to competition next season,” said Justin Dillon, the senior director of athlete high performance for U.S. Figure Skating.
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Actress Maia Campbell appears healthy and sound of mind in new photos shared on Instagram over the weekend
the former ‘In the House’ star posted a candid photo of herself with hairstylist and makeup artist Jayson Glenn
television producer Corey Love and another friend
as the actress hasn’t shared an Instagram update of herself since 2017
Campbell’s last post was an ‘In the House’ throwback for the show’s thirteenth anniversary
One of Campbell’s last updates was in 2020, when she was arrested following an illegal street racing competition in Atlanta. Just ten years before, Campbell was arrested for petty theft.
And the update she’s sharing now seems to be a step in the right direction
it seems things have finally taken a turn for the better as Campbell recently posted a brand new selfie with her hairdresser Jayon Glen on Instagram over the weekend
Campbell looked stunning in the photograph with many of her fans and followers noting how well she looked after all the hardships she faced
Best wishes,” wrote one user in her comments section
“God can turn it all around,” another user said
one thing Campbell hopes to also get turned around is hee career in Hollywood and she subsequently called one major Hollywood player to help her do so: Tyler Perry
Campbell explained how she wants Perry’s help in bringing to life her late mother Bebe Moore Campbell’s book
“72 Hour Hold.” Campbell’s mother passed away in 2006
It was a New York Times bestseller and July is Mental Health Awareness Month
Thank you for praying for me and I’m gonna do my best to make you guys happy.”
Perry has yet to officially respond to Campbell’s request but if he does
this might just be the restart and revival that could prove fruitful to her ongoing career
Actress Maia Campbell made a name for herself in the ’90s thanks to her talent and natural beauty
She was most known for her role as Tiffany on the hit TV sitcom In The House, which she starred in with LL Cool J
Campbell’s life took a turn and spiraled out of control when she began using drugs intensively
She’s been very candid about her journey with addiction
which resulted in jail time and losing custody of her daughter
she appeared as a guest on OWN’s Iyanla Fix My Life
Over the weekend, Campbell posted an Instagram photo of her and celebrity hairstylist and makeup artist Jasyson Glenn
A post shared by Maia Campbell (@maia_campbell)
The photo was the first Campbell had shared of herself on Instagram since May 2017
causing an outpouring of encouragement from her supporters.
God is truly amazing,” one fan commented
“😍😍😍😍 LOOK AT GOD 🙏🏾,” another person added
“I’m really gonna cry. You’ve literally been in my prayers for years
My first representation of seeing a brownskin girl really make it ❤️this makes my heart so happy to see that forever glow,” someone else wrote
Overwhelmed by the public’s love, Campbell followed up with a video to confirm that she was doing well
accompanied by the caption: “Thank you all for the love and support ❤️❤️❤️ more to come.”
Thanks for checking in and wondering if I’m okay,” she began
She also teased what her futures look like. One of her wishes is to work with Tyler Perry and develop a movie based on her mother Bebe Moore Campbell’s 2005 book, 72 Hour Hold.
“Everybody keeps asking me what I want to do with my career. And honestly, I could say that I really want to get in touch with Tyler Perry and have him produce my mother’s book 72 Hour Hold,” Campbell said. “It was a monumental book for me. It was a New York Times Best Seller, and July is Mental Health Awareness Month, so I’m still on that campaign.”
Campbell ended the video by requesting continued prayers as she aims to stay on a successful path of recovery.
“Keep me up in prayer and thank you for praying for me,” she said. “And I’m going to do my best to keep you guys happy. I’ll see you soon. Bye!”
View this post on Instagram A post shared by Maia Campbell (@maia_campbell)
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This year’s must-see shows range from a Nordic Pavilion exploring transgender spaces to a compelling Lebanese project confronting the realities of ecocide
Frieze returns to The Shed in May with more than 65 of the world’s leading contemporary art galleries and the acclaimed Focus section led by Lumi Tan
The Filipinx American artist describes the ‘deep cellular shift’ they experienced while researching their new paintings for Frieze Los Angeles
Maia Cruz Palileo works within the ‘darkness’ of American governmental archives of photographs
Palileo’s paintings and sculptures reflect the landscape of the Philippines
their family’s migration to the US from Manila and the colonial relationship between the two countries.
Ahead of their solo show with David Kordansky Gallery at Frieze Los Angeles
Palileo discusses their recent transformational visit to the Philippines
the ‘liberation’ they find through collage and how their ‘favourite painting is the next painting.’
Livia Russell Can you talk about your new work for Frieze Los Angeles?
Maia Cruz Palileo All the new work is going to be paintings
This body of work kicked off around this time [January] last year
It was a different kind of trip for me because I wasn’t just tagging along with my family
My cousin and I were both really interested in visiting the town that my family is from
and I had other interests in this region that is known for some inactive volcanos and spiritual pilgrimages
It’s different looking at it from over here [the US]
but then on this trip I didn’t have to imagine
This is the river they talked about; that’s the street my grandma lived on; people know us
is the thing that fills in all the gaps. Maia Cruz Palileo
or there’s crazy overgrowth that feels suffocating
there’s something about that constant movement that helps to keep it moving in the space
LR How is your work currently evolving?
MCP The figures in my work have slowly started to meld into the landscapes
This seamlessness happened somewhat as a mistake
it’s almost like all those empty spaces get filled up with whatever’s underneath it
I started playing around with taking the same image and duplicating it
scrambling the figure with the environment
Another line of research has been about the Hudson River School painters and their techniques to dramatize space
showing scale by using a tiny figure and utilizing the Indigenous people of those places
They would even make them up – maybe they didn’t even wear those clothes or didn’t wear clothes at all
I try to counter that and not have the typical tools to make landscape
As an artist I used to struggle with this: it’s lush
LR Are there other sources of inspiration in your new work
MCP The resources that I have been using for this new body of work are a combination of historical archival material – American governmental archive photographs of the colonial period from 1905 to 1920 and images from a botanic school that was established by the US – and my own personal pictures from when I was in the Philippines
I spent time in the archives at the University of Michigan doing this research
The postcards and most of the materials that come from the archive are very flat and lifeless
I had a deep cellular shift just from being there in that space for two weeks
I’ve been working with them for so many years that I feel like I’ve ingested it all
it comes out in this way that has been masticated and processed
The way that the archive material is amassed is so dark
I committed to portraiture to go against what I saw in archives: these anthropological photographs that were really dehumanizing
The first time I started cutting things out
There was a very distinct agenda and narrative to these images
I’m just literally going to chop this up and rearrange it
as opposed to the static sense of those archival works.
LR How does your imagination connect with reality and memory?
it’s really hard to have imagination because everything’s already there for you
The objects in the collection retain an opacity
although you can read between the lines.
I was committed to portraiture as a way to go against what I saw in the archives
I was seeing these anthropological photographs that were really dehumanizing
My reaction to that was noticing that sometimes the people were staring back in this way that was very intense
It involves a lot of care to render a person in this way
when I would ask my grandma to tell me stories
What’s in that empty space that’s not being told
Or I would look at old pictures where someone had their finger over the flash
I’ve been making one gigantic body of work this year
and in the show there will be sculptures and ceramics related to the paintings and featuring lots of animals.
I’ve been invited to collaborate on a project with a scientist at the University of Michigan
She’s researching the effects of pesticides in banana plantations in the South of the Philippines
The show will be about fungus; about how fungus is like anarchy
they’re trying to fight two fungi that are killing their crops
I’m learning about the colonialism that’s happening in these plantations right now
The way that art can open a different channel of research
LR What does time in the studio mean to you?
MCP I’m like an office worker; I work nine to five
What I like about painting is that it happens over a long time
The challenge is re-entering it and seeing it through
It goes through all the different phases: it’s ugly
My favourite painting is the next painting
My studio is in the Brooklyn Army Terminal
I’ve been here since 2012 and I’ve moved around the building: it’s like three blocks long
One day I came in here and the whole studio was hot pink – it’s not called Sunset Park for nothing
Maia Cruz Palileo is presented by David Kordansky Gallery at Frieze Los Angeles 2025.
Frieze is proud to support the LA Arts Community Fire Fund
10% of the value of all newly purchased tickets is also being donated to the fund.
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Frieze Los Angeles is supported by global lead partner Deutsche Bank
continuing its legacy of celebrating artistic excellence on an international scale
Maia Cruz Palileo is an artist based in New York
The Indonesian artist reimagines inherited mythologies in her new beaded cow hide paintings for Frieze New York
The London-based artist talks about the new paintings she’s bringing to Frieze New York and how her figureless works are ‘portraits’
A background in engineering and a fascination with the origins of energy powered a formidable career in art
Participants describe a ‘much-needed boost’ to the LA community and a vital moment for the international art world
The Los Angeles filmmaker was awarded for her work Grief Cannot Exist Without Joy
Christopher Guerrero won the Audience Award
The K-pop star and actor chooses a dramatic painting by Janaina Tschäpe and a deeply meditative piece by Park Seo-Bo
The annual acquisition fund is awarded to an LA-based artist at the fair
selected by a jury including Jay Ezra Nayssan
The fair opens at Santa Monica Airport with immersive solo shows
community initiatives and artists’ projects
founder and director of Art Made Between Opposite Sides
explains its show of ‘Coquestas Frutas’ (Sexy Fruit) created by LGBTQ migrants waiting across the Mexican border
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Maia Campbell seeks to make a comeback in entertainment with the help of Tyler Perry
The actress, who returned to Instagram over the weekend with her first new photos in nearly eight years
Campbell shared her hope to adapt the 2005 book “72 Hour Hold,” written by her late mother
‘what do I wanna do with my career?’ And honestly
I can say that I really wanna get in touch with Tyler Perry and have him produce my mother’s book
Thank you for praying for me and I’m gonna do my best to make you guys happy,” Campbell concluded
Moore Campbell died in November 2006 at 56 after a battle with brain cancer. “72 Hour Hold” was the late author’s final novel, centered on a mother, Keri, who attempts to support her bipolar daughter, Trina. In reality, Campbell was diagnosed with bipolar disorder in 1998 and has struggled with the condition, in addition to substance abuse.
In 2012, Campbell appeared on the former reality show, “Iyanla: Fix My Life,” where she came to terms with her mother’s passing and their contentious relationship.
was riding in the back of her father’s bicycle on Lakeshore Avenue near Hanover Street when a driver opening their door into the bike lane caused them to crash in August 2023
Honoring The Life of Maia Correia; Lakeshore Bikeway; Black History Month Honoree; Home Match; Immigrant Community Vigil; The Oakland Roots
succumbed to thatinjury at Children’s Hospital
Maia’s family and community celebrated her life cut short
andmourned her passing as the fifteenth traffic death in 2023
Maia’s tragic death has galvanized her family as active advocates
to make ongoing improvements in bicycling safety and conditions around Lake Merritt
one of the most utilized recreation areas in Oakland
The District 2 Office of Councilmember Rebecca Kaplan and the At-Large Council Office of Rowena Brown
along with Alameda County Supervisor (former District 2 Councilmember) Nikki Fortunato Bas
find the life and legacy of Maia Correia should be honored and recognized
By successfully identifying available existing Measure BB money (voter-approved countywide transportation funding)
we were able to advance this important project
I was honored to continue the work of former district 2 councilmember Nikki Fortunato Bas
and partner with my council district colleague from the At-Large office
I was moved by the heartfelt words of the Correia family who helped create this resolution and spoke at the City Council meeting
In celebration of Black History and Futures Month
founder & executive director of Urban University
who has over 30 years of experience building upward mobility alongside impoverished and unhoused communities through workforce development collaborations
Tracey is co-founder of the Oakland Transitional Housing Alliance; a new Advisor to the Grand Avenue Business Association
the Executive Program in Social Entrepreneurship at Stanford Graduate School of Business
Tracey holds dear the testimony of her hard-working mother
along with the life skills gained raising two children solo while striving to create an organization that stands as a beacon of light in Oakland
Preventing displacement and homelessness means finding not just any living arrangement but a compatible one
Home Match connects individuals based on their preferences and habits
The program helps with the financial burden on older individuals
create a more affordable living arrangement
mitigating the threats of displacement and homelessness
The District 2 Office is proud to support the adopted measures and existing ordinances that support Oakland's diverse migrant community
District 2 Staff joined the community vigil in support of migrant communities in Oakland organized by Faith In Action East Bay
which took place from Fruitvale Plaza to St
It is important to connect in these community spaces
take time to acknowledge each other and the energy required to continue to show up
In the increasingly uncertain atmosphere that has been created since January 20th
we need to gather and remind each other of the tight bonds of community
Mass deportations are illegal and amoral of immigrants and first-generation citizens
We must continue to raise up our voices against racism and bigotry and stand united together
Experience all of the exciting group options available at Oakland Roots games at the Oakland Coliseum
Roots games are a great way for your friends
youth and adult soccer teams or families to get together and enjoy a memorable experience at a Roots game
The Roots are pleased to offer discounted group seating for groups of 10 or more guests
Please contact to inquire about the 2025 Season
For questions and to reserve tickets please contact tickets@rootssc.com or (510) 488-1144
For information on single-ticket games, please click here.
Premium spaces and group packages are available for Club Oak, Field Boxes, President's Suite, and the Dugout here.
Rebecca Kaplan is an honors graduate of MIT and Stanford Law School
Kaplan was elected in 2008 to serve as Oakland’s citywide Councilmember; she was re-elected in 2020
her colleagues unanimously elected her to serve as Oakland's Vice Mayor
Kaplan also serves on the Metropolitan Transportation Committee and the Oakland- Alameda County Coliseum Authority Board (OACCA)
Rebecca Kaplan for City Council 2020 Officeholder
FPPC ID #14422741714 Franklin #100-451Oakland
THIO improved patients’ overall survival when taken in combination with Libtayo
A treatment for patients living with advanced non-small cell lung cancer (NSCLC) who failed two or more standard-of-care (SOC) options could extend overall survival (OS) to 16.9 months according to updated results from MAIA Biotechnology’s Phase II trial
The Chicago-based company has announced updated data from its THIO-101 pivotal Phase II trial (NCT05208944) examining its lead candidate
an investigational telomere-targeting agent sequenced in combination with Regeneron’s Libtayo (cemiplimab)
a programmed cell death protein 1 (PD-1) inhibitor
Libtayo was approved by the US Food and Drug Administration (FDA) as a first-line (1L) therapy for patients with locally advanced or metastatic NSCLC with 50% or more PD-L1 expression
said: “Treatment with THIO now shows a 99% probability that OS will extend past chemotherapy’s measure by a wide margin
“THIO’s efficacy in advanced stages of NSCLC continues to exceed our expectations
especially in 3L treatment where the cancer is typically even more resistant to therapy
Our findings suggest great benefits to patients with unmet medical needs who see little hope for the future.”
The primary endpoints of the trial were safety and tolerability of THIO as an anticancer drug and priming immune activator, alongside clinical efficacy demonstrated in the form of overall response rate (ORR). The company met both of those endpoints in initial results from the Phase II trial, announced in March 2024 with an ORR of 38%.
Don’t let policy changes catch you off guard
Stay proactive with real-time data and expert analysis
The company added that sequential treatment with THIO followed by PD-1/PD-L1 inhibitors resulted in sustained tumour regression in advanced in vivo cancer models
the company is looking to parse its success into approval before the US Food and Drug Administration (FDA)
A report published by GlobalData in October of last year found that across the seven major markets (7MM: US
revenue from NSCLC treatments is expected to see a significant expansion from 2022’s $25.2bn to 2032’s $63.5bn
expedited by more than 40 pipeline treatments currently in trials
GlobalData is the parent company of Clinical Trials Arena
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View all newsletters from across the GlobalData Media network.
The brother-sister duo will compete in the upcoming season ahead of the 2026 Winter Olympics in Italy
Alex and Maia Shibutani at the 2018 Winter Olympic Games
Olympic bronze medalists Alex and Maia Shibutani are making a surprise return to competitive figure skating after more than seven years away from the sport. The brother-sister duo, known as the Shib Sibs, announced this week that they will compete in the upcoming season ahead of the 2026 Winter Olympics in Milan-Cortina, Italy.
The Shibutanis last competed at the 2018 Pyeongchang Olympics, where they earned bronze in both the ice dance and team events. They did not formally retire but stepped away from competition, later pursuing creative projects including authoring children's books. In 2019, Maia underwent surgery to remove a cancerous tumor from her kidney.
Alex and Maia, now 34 and 30, will train with longtime coaches Marina Zoueva and Massimo Scali as they aim for a third Olympic appearance. Their return adds to an already competitive U.S. ice dance field, led by reigning world champions Madison Chock and Evan Bates.
View this post on Instagram A post shared by Maia Harumi Shibutani (@maiashibutani)
I’m so happy and grateful to be healthy and in a position to make the decision to return to the sport I love in this way."
Daniel Anderson is a disabled Chinese American adoptee based in Seattle. His freelance writing specialties include K-pop, entertainment, and food. He believes that any restaurant can be a buffet, and the key to success is to take a nap each day. Follow his adventures on Instagram @danzstan
Gold House will host its fourth annual Gold Gala on May 10 in Los Angeles and celebrate the theme of First Lights with more than 600 guests
The Golden State Valkyries coach is "setting the standard" and opening the door for more Asian women in the sports world
The Icelandic Chinese jazz musician says "the support and scholarships I received as a child have directly led to the career I have now"
but it was still a huge accomplishment at the time
The Vietnamese American first joined Billboard as president in 2022 and helped launch the Billboard Women in Music event
and more at the first major golf tournament of the year
This MAIA project webinar showcased a suite of knowledge tools developed to support climate decision-making
The webinar featured SEI Senior Research Fellow and weADAPT developer Sukaina Bharwani
who discussed the latest advancements in MAIA’s Climate Connectivity Hub and Climate Change Taxonomy
Photo: Dibakar Roy / Unsplash
Timely, reliable information is vital to tackle climate change. But it is not always easy to find, navigate or use. The Maximising impact and accessibility of European climate research (MAIA) project brings together knowledge tools to bridge the gap between you and what is out there by transforming how you access
The MAIA Knowledge Tools Launch Event showcased its tools
which were specifically designed to meet the needs of climate action practitioners and researchers
Learn more about MAIA knowledge tools
The video recording of the session will be uploaded here as soon as it is available
introducing the goals and scope of the MAIA project
Sukaina Bharwani (SEI), presenting innovations underpinning MAIA’s Connectivity Hub and Taxonomy.
Dennis Halvik (AIT), introducing MAIA’s SumarAIse tool.
Andrea Geyer (SCC), introducing MAIA’s Discovery Services.
Get the latest updates and invitations to your inbox with SEI’s global newsletter.
'I'm doing great! I just wanted you to know that.'
Beloved ’90s actress Maia Campbell shook the internet on April 13 when she returned to social media. Best known for her roles in In The House, Sister Sister, and South Central, Campbell discussed her career prospects after a hiatus from the public sphere.
Over the weekend, Campbell dropped a photo of herself on Instagram, smiling with celebrity hair and makeup artist Jayson Glenn.
It was Campbell’s first photo on Instagram since May 2017, and her healthy glow drew an outpouring of support from her longtime fans.
View this post on Instagram A post shared by Maia Campbell (@maia_campbell)
In response, Campbell posted a video on Instagram to confirm that she has been doing well. She captioned the post, “Thank you all for the love and support. More to come.”
In the video, she began, “Hey everybody! Thanks for checking in and wondering if I’m OK. I’m doing great! I just wanted you to know that.”
She continued to drop some hints about what her future projects might look like, revealing that she hopes to work with Tyler Perry to produce a movie based on her mother, Bebe Moore Campbell’s 2005 book, 72 Hour Hold..
“It was a monumental book for me. It was a New York Times bestseller, and July is Mental Health Awareness Month, so I’m still on that campaign,” she said.
Campbell concluded the heartfelt video by thanking her fans for their continued support and asking for people to keep sending prayers her way as she pushes forward in the recovery journey.
and thank you for praying for me,” she stated
“And I’m going to do my best to keep you guys happy
Campbell was iconic in the ’90s due to her natural beauty and charm on hit sitcoms
she fell from the public eye after she began using drugs
In a journey that she has openly discussed
Campbell battled with addiction and spent time in jail
After appearing on Iyanla’s Fix My Life
RELATED CONTENT: Karmelo Anthony Released From Jail After Texas Judge Lowers Bond From $1 Million To $250K
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desperately trying to lock in for my prelim tomorrow
but I can’t stop thinking about all of the things I want to say in my very first article of my very first column
I can’t help but reminisce about every decision I’ve ever made in my life
And this sense of urgency and depth in thought pretty much sums me up as a person
Because this is the first time you’re hearing from me
I think it’s important to communicate some of my own personal values that I have developed over the two years of me being a student at Cornell
From living in a house with 40 other girls to writing for The Sun
I am surrounded by opinions on a daily basis
I thought it was time I share some of mine in the best way I know how
I want to talk about one of the most important aspects of my life: my friends
There are some things I am extremely passionate about in this life: women’s rights
nothing gets me going quite like talking about the importance of strong
My friends here have consistently shown up for me in the most unimaginable and invaluable ways
and they’ve taught me so much about what it takes to show up for them too
Having had a tight-knit friend group in high school
I was terrified at the thought of never finding people that invoked the same level of love
The friends I have made since my first day on campus
and it is safe to say that they have changed the trajectory of my life
Though this statement may lend itself to the fact that we are at one of the most prominent and selective universities in the country
the people here that I have gotten to know and love inspire me every single day
Between being international champions in their niche sports and activities (one of my best friends is literally a jump rope champion) and having such passion for their respective academic and career fields
there is no shortage of talent and dedication among my friends
They certainly push me to be the best version of myself
and I feel immense pride in them and their achievements
they are still my biggest cheerleaders when it comes to mine
they have taught me the gravity of displaying outward and unequivocal support for my loved ones
Having recently gone through a breakup as someone who is relatively new to relationships
I was unsure of how to navigate uncharted waters
or how intense the waves in these waters would even be
extracurricular obligations and the emotions that come with being a 19-year-old girl existing on this planet (like many others at this university)
it took not one ounce of verbalization from me for my friends to sniff out my melancholy and act
my roommate and our best friend exchange a glance
when one left and came back with her hands occupied with a woven basket full of goodies
my body just kind of melted into itself (my friends can attest to this statement)
and we wanted to show how much we love you,” my roommate said
To say I was overwhelmed with a deep feeling of gratitude is a colossal understatement
as I recognized an act of service such as this required my friends to take time out of their incredibly busy schedules to put together this basket full of chocolate (classic)
These “thinking of you” baskets have become a staple among my friends
I think they could really put things in perspective for a lot of others on this campus too
In an environment riddled with intensely rigorous academics and roaring competition
The fierce chill characteristic of Ithaca winters doesn’t help either
I am so tired of a busy schedule being the excuse for being a bad friend
I am not saying to shower your friends in expensive gifts and overwhelm them with cheesy messages
I am simply advocating for a little bit more consideration when it comes to the fact that
you do have to maintain friendships if you want to continue to have them
It should feel good to uplift those you love
even if that is in the form of a simple “Hey
how are you?” text message every once in a while
your friends should display their love for you in the ways you need it most
and if you have any doubts about if your friends are in it for the long haul
I really hope some Cornellians pick their heads up from their computers and recognize the value of
social interaction and genuine relationships with others
And I don’t mean putting all of your eggs in one basket (cutting off your relations with your friends and prioritizing a romantic partner)
I will always make my friendships a priority and brainstorm the ways in which I can foster these relationships further
Maia Mehring is a Lifestyle co-editor on the 143rd editorial board
She is a sophomore in the School of Industrial and Labor Relations and can be reached at mmehring@cornellsun.com
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US siblings Maia and Alex Shibutani announced Thursday they are coming out of retirement after seven years to compete in the 2025-26 season with an eye on next year's Winter Olympics in Italy
Two-time Olympic medallist ice dancers Maia and Alex Shibutani announced their return to competition for the 2025-26 Olympic season on Thursday
seven years after the US siblings retired from the sport
captured bronze medals in team and ice dance at the 2018 PyeongChang Winter Olympics and took world ice dance silver in 2016 at Boston and bronzes in 2011 and 2017
and inspired by new possibilities," Maia Shibutani posted on social media
"We love skating and have decided to compete in the upcoming 2025-26 Olympic season
@alexshibutani and I have been working hard and we can't wait to perform together again."
will be coached by Marina Zoueva and Massimo Scali
who had guided the duo before their retirement
The siblings stepped away from competition in 2018 and Maia was then diagnosed with kidney cancer a year later
they wrote four children's books and served as choreographers
"These past seven years have challenged and inspired us in ways we never expected," Maia Shibutani said
"I'm so happy and grateful to be healthy and in a position to make the decision to return to the sport I love in this way."
Alex Shibutani said new routines will reflect their growth during the time away from competition
"Our experiences and the new skills we've developed during our time away from competition have brought us different perspectives and created some exciting new possibilities," he said
The 2026 Winter Olympics will be held in Italy next February
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The Arts Inspire at Davidson
Diversity & Inclusion
Maia Harrell ’20 was a chemistry major at Davidson and opened a small business back home in Atlanta
She has now returned to campus and works in the Office of Alumni & Family Engagement as the assistant director for regional engagement
connecting Wildcats all across the country
Harrell with Davidson girlfriends their freshman year
Maia followed a strong line of women to Davidson
She is pleased about the opportunity to give through the Wildcat Women Fund and make a difference for those following in her Davidson footsteps
I take both of those identities very seriously
My blackness was supported by the Black Student Coalition (BSC) as a student and the Davidson Black Alumni Network (DBAN) as an alum
but my woman-ness has not been supported in the same direct way
Giving to the Wildcat Women Fund will ensure direct support to — and with — other women Wildcats like me
Maia Harrell with Emily Magen ’20 and her mom when Brian Stevenson spoke on campus
I grew up surrounded by Davidson women: my mom
my godmother and too many play-aunts to count
I grew up seeing their power and seeing how they embodied what it means to be a Davidson woman
"A Davidson man needs no introduction," but quickly changed it to “A Davidson WOman needs no introduction" once I became one
I am most excited to see how this fund will support women at Davidson
especially with the current political climate taking rights and services away from women
I hope this fund will mitigate these effects to the women and women-identifying students at Davidson
Harrell with RLO co-workers and former residents at Fall Fling her sophomore year
I hope this fund will allow the women and women-identifying students at Davidson access to the necessary healthcare they need
I hope we can serve as a model for other institutions to continue to directly support and care for a large part of the student body
I didn't have the best student experience at Davidson; some of it personal and some it institutional
I believe giving back will allow me to make real changes to areas of campus I loved when I was a student
and areas I believe need to be improved from when I was here
(704) 894-2000
Today our “Star Trek Fleet Command” team is introducing its first-ever
“Maia,” expanding the game’s universe with a cinematic narrative experience created to captivate longtime Star Trek fans and new players alike.Featuring Star Trek legend LeVar Burton as Geordi La Forge
“Maia” presents a thrilling storyline inspired by a player’s very first mission in “Star Trek Fleet Command.”In this visually stunning adventure
Geordi and the independent crew of the Realta face imminent danger from a Klingon attack and encounter Maia
Maia’s introduction marks the beginning of exciting new possibilities in storytelling
character development and narrative innovation for “Star Trek Fleet Command.” Check out the video here!Mu751u8JnsnZSJ" title="YouTube video player" frameborder="0" allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" referrerpolicy="strict-origin-when-cross-origin" allowfullscreen>
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How to treat high-risk myeloma at diagnosis and relapse
Clinical course of patients with relapsed multiple myeloma
Survival and outcomes of newly diagnosed multiple myeloma patients stratified by transplant status 2007-2018: retrospective analysis from the Canadian Myeloma Research Group Database
The clinical course of multiple myeloma in the era of novel agents: a retrospective
Treatment of multiple myeloma with high-risk cytogenetics: a consensus of the International Myeloma Working Group
Multiple myeloma: 2020 update on diagnosis
Multiple myeloma with high-risk cytogenetics and its treatment approach
Daratumumab in transplant-eligible patients with newly diagnosed multiple myeloma: final analysis of clinically relevant subgroups in GRIFFIN
Revised International Staging System for multiple myeloma: a report from International Myeloma Working Group
Interpreting clinical trial data in multiple myeloma: translating findings to the real-world setting
Defining and managing high-risk multiple myeloma: current concepts
High-risk multiple myeloma: how to treat at diagnosis and relapse
Presented at: European Hematology Association (EHA) Hybrid Congress; 2024; Madrid
International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma
A simplified frailty scale predicts outcomes in transplant-ineligible patients with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial
Daratumumab plus lenalidomide and dexamethasone in transplant-ineligible newly diagnosed multiple myeloma: frailty subgroup analysis of MAIA
International Staging System for multiple myeloma
IMWG consensus on risk stratification in multiple myeloma
group of newly diagnosed myeloma identified by genomic analysis
Daratumumab plus lenalidomide and dexamethasone (D-Rd) versus lenalidomide and dexamethasone (Rd) alone in transplant ineligible patients with newly diagnosed multiple myeloma (NDMM): updated analysis of the phase 3 MAIA study
Presented at: 64th American Society of Hematology (ASH) Annual Meeting & Exposition; 2022; New Orleans
and dexamethasone with or without daratumumab before and after autologous stem-cell transplantation for newly diagnosed multiple myeloma (CASSIOPEIA): a randomised
Chromosomal 1q21 abnormalities in multiple myeloma: a review of translational
The independent adverse prognostic significance of 1q21 gain/amplification in newly diagnosed multiple myeloma patients
Gain of chromosome 1q is associated with early progression in multiple myeloma patients treated with lenalidomide
Chromosome 1q21 abnormalities in multiple myeloma
Amp 1q21 is more predictable with dismal survival than gain 1q21 of newly diagnosed multiple myeloma in real-world analysis
Concepts of double hit and triple hit disease in multiple myeloma
Experts’ consensus on the definition and management of high risk multiple myeloma
and dexamethasone as induction and extended consolidation improves outcome in ultra-high-risk multiple myeloma
Lenalidomide maintenance versus observation for patients with newly diagnosed multiple myeloma (Myeloma XI): a multicentre
Ixazomib significantly prolongs progression-free survival in high-risk relapsed/refractory myeloma patients
Elotuzumab therapy for relapsed or refractory multiple myeloma
Subgroup analysis of ICARIA-MM study in relapsed/refractory multiple myeloma patients with high-risk cytogenetics
Primary outcomes by 1q21+ status for isatuximab-treated patients with relapsed/refractory multiple myeloma: subgroup analyses from ICARIA-MM and IKEMA
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Karolinska University Hospital at Huddinge
and SKK contributed to the study conception and/or design; PM
and SKK contributed to data acquisition; PM
and SKK contributed to data analysis; and PM
and GlaxoSmithKline; and received research funding from bluebird bio
a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law
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DOI: https://doi.org/10.1038/s41375-024-02506-1
Director Dean Fleischer Camp provided some potential insight on how that happened
and it involved an adorable "stuffie" routine Maia Kealoha had before leaving the set each day
and they developed a real bond during filming:
I was pretty passionate that Maia would need something to act opposite
when you’re spending money on a movie
could she just act with a tennis ball if we’re going to be replacing Stitch entirely?’ It just felt like this was the heart of the movie and she needed to have a proper scene partner..
‘Get him out of the truck and get him on the rig’
This Side-By-Side Comparison Of Lilo & Stitch Animated And Live Action Are Almost Identical, And I Kind Of Feel Like That's The Problem
I don't think there was any denying Lilo & Stitch was going to have heart
and remains a fan-favorite Disney movie to this day
The question that surrounds every remake of a Disney original is how will it differentiate itself from the animated version
I think that everyone wants to see a lifelike version of Stitch run around and cause mayhem with a bunch of live-action actors
And behind-the-scenes stories like these make me very excited for what will play out onscreen
Wholesome entertainment for all the family
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Perhaps I'm asking the wrong question about an upcoming kids movie
I should be asking how kids will respond to seeing Maia Kealoha interact with Stitch
and how many will desperately hope to get their own pet alien to go on adventures with
I think some adults get caught up in their own nostalgia being tapped in Hollywood
and they forget about the generation of children who might not have seen the movie yet
I'm sure my kid will be a fan regardless of box office earnings and whether it was a necessary remake
Lilo & Stitch is officially hitting the movie release schedule on May 23rd
but he also regularly reports on happenings in the world of Star Trek
He graduated from the University of Southern Indiana with a degree in Journalism and a minor in Radio and Television
He's great at hosting panels and appearing on podcasts if given the chance as well
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‘That Was The First Time I’d Seen Him Nervous’: Mission: Impossible’s Simon Pegg Recalls The Stunt That Even Had Tom Cruise Feeling Uneasy
President Trump Threatened Massive Tariffs On The Film Industry
But There Are Some Basic Questions That Need To Be Answered
Watch James Gunn’s Dog Go Crazy Watching Superman’s Krypto (Which Was Totally Based Off Him)
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