The company behind the phone-size Palma e-reader has released a 25.3-inch color desktop display by Andrew Liszewski FacebookThreadsIf you buy something from a Verge link, Vox Media may earn a commission. See our ethics statement. Boox is debuting its first desktop monitor featuring a color E Ink screen. The new version of the Boox Mira Pro carries over the same functionality as the black-and-white version that launched in 2023, but using the same E Ink color display technology found in devices like the Kindle Colorsoft E Ink offers several advantages to display technologies like LCD and OLED including a screen that reflects light instead of emitting it so it’s potentially easier on the eyes for prolonged use The Mira Pro Color is only 25.3-inches in size but is priced at $1,899.99 Boox also says its Mira Series of E Ink monitors only ship from China and “some countries may levy tariffs on the imported goods.” If you’re having one shipped to the US The Mira Pro Color features front lighting similar to what’s found in e-readers with the option to adjust the color temperature to warmer hues at night. It’s also got a pair of speakers, a dedicated refresh button on the side to remove ghosting, and five ports including HDMI, mini HDMI, USB-C, and DisplayPort. If you’re a gamer, photo or video editor, or someone who uses their desktop monitor for watching TV and movies, the Mira Pro Color isn’t for you. But if you spend your days editing text, writing, or crunching numbers in spreadsheets in a space with plenty of light, an E Ink monitor might be worth considering, particularly if you find yourself frequently dealing with eye strain. A weekly newsletter by David Pierce designed to tell you everything you need to download, watch, read, listen to, and explore that fits in The Verge’s universe. why would investors put in so much money and value such a young enterprise at around $10 billion If Thinking Machines Lab turns into a success like these two companies then your venture capital fund is done for the decade so the rest of your portfolio of early startups doesn't really matter Those businesses can all fail and you've still generated impressive returns "Each year brings a handful of outliers that hit the proverbial grand slam," wrote Sebastian Mallaby in his 2022 book on the subject "The only thing that matters in venture is to own a piece of them." If Thinking Machines doesn't do amazingly well there's another path where investors can still make money — even if they've put what seems like a ridiculously high valuation on this startup.  startups that struggle to sell products and generate revenue still have other valuable assets Maybe they've invented a new tech thing and have patents to back it up Murati is incredibly talented and she's hired quite a few experts from her OpenAI days) big tech companies sometimes swoop in and acquire these startups When these transactions are mostly for talent when tech companies are racing for domination Amazon did a similar one with Adept.  These types of transactions don't generate 10x or 100x returns for VCs But they can get them out of struggling startup investments with little financial damage or sometimes even a relatively healthy gain For instance, the Character.ai deal netted investors a return of about 2.5x, BI's Ben Bergman wrote last year.  Let's call this the "Big Tech put."  A put option is a financial contract that gives the owner the right to sell an asset at a specific price by a specific date a put is the idea that if the price of something falls a lot someone important will step in and support it it's the idea that if the sh*t hits the fan higher powers will intervene to clean up the mess.  If broader markets can have "put" theories then why can't venture capitalists have their very own "Big Tech put" Mira announces a partnership with global soccer star Ali Riley who plays for Angel City FC and New Zealand Women’s National Team The collaboration aims to support women as they navigate major life transitions by encouraging open conversations around hormone health and expanding access to personalized As Riley rehabs what could be a career-ending injury she’s opening up about the emotional and physical toll of IVF — and the role hormone tracking played in giving her back a sense of agency Riley began monitoring her hormone levels with Mira unsure if motherhood was even possible for her “So many parts of my life this year have felt  up in the air It gave me concrete information  to rely on Having this resource was powerful — the one thing I knew I wanted when  I wasn’t able to play soccer or spend time with my team And that was to have the option of having a baby.” she decided to pursue IVF and continued using Mira throughout her cycle “I felt like I had a roadmap in front of me,” she said “When I saw that I was still in a late reproductive phase And being able to track my levels at home during IVF gave me peace of mind between doctor’s appointments — I wasn’t left wondering what was happening inside my body.” Mira’s technology offers lab-quality hormone tracking from home — a breakthrough for those undergoing fertility treatments. It’s the first at-home hormone monitor validated for fertility treatments offering clinical-grade accuracy with real-world convenience One study found that tracking urine E3G with Mira showed a similar correlation to the number of eggs retrieved during IVF as standard blood-based estradiol testing These early findings suggest that at-home hormone monitoring could play a meaningful role in improving both the patient experience and the overall delivery of fertility care — particularly for those navigating treatment in high-pressure or time-sensitive phases of life “Ali’s story is a powerful reminder that knowledge is the foundation of confidence,” said Sylvia Kang “We’re proud to support her journey and to continue delivering science-backed tools that empower women to understand their bodies at every stage.” Mira and Ali Riley aim to raise awareness around the emotional and physical realities of fertility treatment while also redefining what support can look like for women navigating life’s biggest transitions she can empower others to feel less alone — whether they’re managing IVF or simply trying to better understand their hormonal health Riley’s experience also shines a light on the systemic gaps in professional sports where reproductive health is rarely addressed “Most research in sports medicine is based on men’s bodies,” she explains “There’s a huge lack of education when it comes to fertility even menstrual cycles — it’s still taboo in many teams.” fertility preservation or IVF can only happen during the offseason and often without much institutional support “There are so many decisions we’re forced to make without the right information or resources,” said Riley “I was lucky to have access to Mira and a strong support system but so many of my colleagues are flying blind Mira is offering to donate hormone-tracking kits to football clubs interested in providing their athletes with better fertility and hormonal health resources Mira and Riley are calling for more transparency and more compassion in women’s health — helping women everywhere feel seen Mira is a San Francisco-based hormonal health company providing integrative care and hormonal testing for over 140,000 customers Mira was founded in late 2015 by a group of scientists and business execs to solve the problem of the unavailability of advanced home health testing The company’s mission is to develop data-driven hormonal health solutions to help women make confident health decisions during every stage of their lives – from the menstrual stage to menopause and website in this browser for the next time I comment Δdocument.getElementById( "ak_js_1" ).setAttribute( "value" About Femtech Insider Advertise with us! Become a Member! Contact us Privacy Policy // Terms of Use How to watch California high school girls lacrosse: Valhalla vs May 6Data SkriveMira Mesa High School travels to face Valhalla High School on Tuesday How to watch Mira Mesa vs. Valhalla girls lacrosseMira Mesa and Valhalla will take the field on Tuesday, May 6, at 6 p.m. PT. Don't miss out on any of the action with NFHS Network The NFHS Network gives you access to live high school sports around the country Follow your favorite team and never miss a game Want to track your alma mater, local team or family member's school throughout the playoffs? NFHS Network has high school lacrosse streaming live plus on-demand replays and highlights of all the action from thousands of schools across America Watch Valhalla vs. Mira Mesa on NFHS Network! All NFHS Network events are available to watch online at and through the NFHS Network Mobile Apps for iOS and Android and TV Apps for ROKU Donald Trump posted a seemingly AI-generated image of him as the pope; the conclave electing Pope Francis’ replacement begins this week Donald Trump posted an image of himself dressed as the pope Sunday referencing the papal conclave due to begin this week was posted on Trump’s accounts across every social media platform the president uses — Instagram Facebook — and subsequently reposted by the official White House accounts The picture of Trump’s trademark glower emerging from under the papal mitre seemed like a nod to nominating himself for the role which, technically, he could be eligible for if he was Catholic. (He’s not, though I suppose he could get baptized in the next few hours.) It wasn’t the first time he’d mentioned taking over the Holy See, saying he was his own “number one choice” for the role Neither of these instances went over well with many Catholic leaders who took offense at the idea that Trump was even considering the idea of declaring himself God — or at least God’s emissary here on earth the extent to which he was kidding is hazy; nearly all of his suggestions the AI-generated video of building a Trump resort in Gaza — carry at least a seed of truth In the case of becoming pope, Trump is certainly aware that he’s not a real possibility to lead the Catholic Church. Still, though, the idea that Trump is ordained by God’s own hand, to execute God’s desires on earth, is not new; Trump supporters have been saying as much since his first term And when he survived an assassination attempt last July they saw it as a clear sign of his divine mandate the image of Trump as pope — were made to appeal to the president’s Christian nationalist base; they’re the ones who already thought he was ordained by God The role they believe God has for Trump is to make America great again by making it Christian And he’s already begun. Trump created a “Task Force to Eradicate Anti-Christian Bias” at the Justice Department devoted to ending “the anti-Christian weaponization of government.” The executive order establishing the task force referenced arrests of Christian anti-abortion activists protesting outside abortion providers and the Biden administration’s declaration of a Trans Day of Visibility as examples of “unlawful targeting of Christians,” and promised to consider topics like returning prayer to public schools And, just last week under Trump’s leadership, Congress added a loophole in a bill to fight antisemitism that allows Christians to promote the harmful idea that Jews killed Jesus The president also announced the formation of a religious liberty commission last week; everyone on it is Christian except for one rabbi ‘Separation between church and state,’” Trump said at the event announcing the new commission For the Christian nationalists who helped put Trump in office ruled by their understanding of biblical values and law — rolling back LGBTQ+ rights limiting or outlawing contraception and abortion Trump’s papal AI slop was a joke But to the Christian nationalists it was meant for And as Trump erodes the separation between church and state the head of a church already — the American church Mira Fox is a reporter at the Forward. Get in touch at [email protected] or on Twitter @miraefox.[email protected]@miraefox I’d like to ask you to please support the Forward American Jews need independent news they can trust At a time when other newsrooms are closing or cutting back the Forward has removed its paywall and invested additional resources to report on the ground from Israel and around the U.S rising antisemitism and polarized discourse This is a great time to support independent Jewish journalism you rely on See our full guidelines for more information, and this guide for detail about canonical URLs subject line “republish,” with any questions or to let us know what stories you’re picking up Copyright © 2025 The Forward Association Murati made plenty of headlines in 2023 and 2024 amid the turmoil and brain drain at OpenAI she's already grabbing more attention for raising a massive new round of funding for her new AI startup In January 2025, BI reported that Murati's startup was seeking $1 billion in seed funding at a $9 billion valuation A representative for Murati declined to comment for this story Murati was named to Time Magazine's list of the 100 most influential people in AI in September 2024 awarded her an honorary doctor of science for her work democratizing tech and making it safer for people to use Murati stepped in to lead the company on an interim basis Murati led the development of ChatGPT and the text-to-image model Dall-E Earlier in her career, Murati worked at Tesla and at augmented reality startup Here's a look at Murati's life and career so far when she won an academic scholarship to study at Pearson College a two-year pre-college program in Victoria Murati participated in a dual-degree program that allows students to earn two degrees from two liberal arts schools in five years She earned a Bachelor of Arts from Colby College in Waterville in 2011 and a Bachelor of Engineering from Dartmouth College's Thayer School of Engineering in Hanover Murati worked at augmented reality startup LeapMotion where she worked on replacing computer keyboards with the tech Murati originally joined OpenAI in 2018 as the vice president of applied AI and partnerships she became senior vice president of research On November 17, 2023, OpenAI's board shocked the tech world by announcing that Altman was stepping down as CEO and as a member of the board The board in a blog post said that it "no longer has confidence in his ability to continue leading OpenAI," adding that Altman was "not consistently candid in his communications." Murati has become known for her more cautious approach to AI and has said she believes it should be regulated As far back as 2023, Murati acknowledged that there are dangers associated with AI particularly when it comes to bad actors misusing the tech she told Time Magazine that it shouldn't be up to OpenAI and other AI companies to self-regulate and that regulators and governments should "definitely" be involved to ensure that AI use is aligned with human values the startup's new flagship model that is faster than its predecessor and can reason across text OpenAI also debuted a custom chatbot at the 2024 Met Gala While weighing in on AI-driven job loss Murati said that some creative jobs might go away "but maybe they shouldn't have been there in the first place." Her comments angered many with one writer telling BI they represented "a declaration of war against creative labor." a move that surprised many people in the tech world she's quietly been working on her new startup which has captured the attention of many in Silicon Valley While little is known so far about the startup it is a research and product lab with the goal of making AI more accessible The startup officially emerged from stealth in February 2025 She's recruited a long list of former OpenAI staffers to Thinking Machines Lab Ex-Meta and Anthropic employees have joined So far, Thinking Machines Lab employees from OpenAI include John Schulman who co-led the creation of ChatGPT; Jonathan Lachman formerly the head of special projects at OpenAI; Barret Zoph a cocreator of ChatGPT; and Alexander Kirillov who worked closely with Murati on ChatGPT's voice mode BI reported that Thinking Machines Lab was raising a $1 billion round at a $9 billion valuation BI reported that Murati doubled her target and was now seeking to raise a $2 billion round which would be the biggest seed round in history Two sources told BI that the round could value Thinking Machines Lab at more than $10 billion Little is known about Murati's personal life At the Cannes Lions Film Festival in 2024 Murati shared a humorous anecdote about her mother's first interaction with ChatGPT was asking the chatbot when Murati would be getting married Murati told Time Magazine that the 1968 movie 2001: A Space Odyssey stirs her imagination the movie's imagery and music in the scene where the space shuttle docks The movie follows astronauts and an AI supercomputer as they journey to space to find the origin of a mysterious artifact Murati also told the magazine she likes the song Paranoid Android by Radiohead which is a poem collection by Rainer Maria Rilke A driving force for Murati's work is achieving AGI AGI would be able to adapt to a broad range of tasks and apply that knowledge to new situations The pursuit of this goal took Murati from Tesla "I very quickly believed that AGI would be the last and most important major technology that we built and I wanted to be at the heart of it," she said recently recalled a “filmy” incident that took place soon after her engagement to the Bollywood actor shared a memorable moment from their arranged marriage In an exclusive interview on the podcast Moment of Silence Mira explained how things changed after Shahid publicly announced their relationship her friends called to inform her that a group of reporters had gathered outside her college gate Later in the interview with Naina Bhan and Sakshi Shivdasani Mira also opened up about the early days of her marriage “I’d like to admit that it was quite isolating because we were just in different phases of life at that time and you look at your friends… I wish I could what she’s doing I couldn’t speak to them as often as I used to ‘Just because you got married doesn’t mean you forget us!’ And I was like The Kabir Singh star and Mira are parents to daughter Misha and son Zain is currently gearing up for his upcoming project Shoaib Akhtar’s YouTube channel also taken down amid escalating digital restrictions Salman Khan gears up for another project after 'Sikandar' setback 'Housefull 5' set to bring Sanjay Dutt and Nana Patekar together on big screen Masaba Gupta's big praise for Hollywood star knows no bounds Ameesha Patel shares unfiltered thoughts on replacing Priyanka Chopra in 'Humraaz' Starlet says pressure has made her physically sick and she doesn’t know if she’ll return to Instagram — or even.. Copyright © 2025. The News International, All Rights Reserved | Contact Us | Authors Staring at a computer screen all day and into the night can be fatiguing for your peepers For certain tasks – such as coding or pawing through documents – an E Ink monitor might be a better fit Boox has launched a 25.3-inch color E Ink display with super-refresh tech called the Mira Pro and now Boox has crashed the party with its own color E Ink monitor The Mira Pro (Color Version) 25.3-inch monitor features Kaleido 3 color E Ink that offers 16 grayscale levels and 4,096 onscreen colors Display resolution is reported to be 3,200 x 1,800 pixels (145 ppi) which seems on the high side for this flavor of color E Ink That's obviously not going to match the billion-plus vivid colors available on many backlit LCD panels but E Ink doesn't use backlighting – it employs adjustable front lights that are considered much kinder to a user's eyes if there's adequate ambient light in the office then users may not need to switch on the dual-tone illuminations at all Boox says that the mellow colors on offer here make "it ideal for tasks that require color differentiation such as reviewing color-coded dashboards or working with complex graphics – perfect for professional workspaces and immersive learning." E Ink on its own can be a bit laggy so Boox has included its super refresh technology in the mix "to enhance refresh rates and image quality while minimizing ghosting." There are four modes available – normal video and slideshow – for choosing the best option for different tasks dark color enhancement and light color filter to suit preferences If remnants of a previous screen's content do get past the automated check points and haunt the current view a physical button on the side of the monitor will initiate a manual refresh There's also a scroll wheel and a function button along the same edge The monitor offers connectivity to a computer It sits on a stylish aluminum stand that supports landscape or portrait orientation Dual speakers provide audio when you need it The Boox Mira Pro (Color Version) isn't cheap and ships direct from China so may be subject to import tariffs This makes it a pricier option than Dasung's Paperlike Color And both are much more expensive than regular backlit computer monitors Product page: Mira Pro (Color Version) E-ink panels traditionally appear on e-readers and signage but some companies started using them for monitors and other general-purpose devices a few years ago The Mira Pro Color makes Boox the latest entrant into the color e-ink monitor market E-reader manufacturer Boox recently introduced a version of its Mira Pro e-ink PC monitor that displays colors Although its media capabilities are far inferior to similar panels from the likes of Asus this monitor might offer a more comfortable and versatile workstation viewing experience Boox updated the Mira Pro with a Kaleido 3 color ePaper panel featuring 16 grayscale levels and 4,096 colors Although the colors might look muted compared to most LCD and especially OLED screens the glare-free e-ink technology consumes far less energy and makes reading text in bright rooms easier The Mira Pro Color primarily targets tasks like reviewing color-coded data and coding for long hours The company hasn't specified the Mira Pro Color's precise refresh rate, but it is probably a fraction of that of the latest gaming monitors. Other e-ink PC monitors from companies like Dasung typically support 40Hz or 60Hz Boox's new offering allows users to customize its responsiveness level toward different tasks to maximize colors or minimize ghosting Four presets are available for web browsing the Mira Pro Color supports a 3,200 x 1,800 pixel resolution at 145ppi and measures 25.3 inches Supported operating systems include Windows but the company warns that it can only ship from China meaning US customers will likely encounter steep tariffs Boox also recently upgraded its seven-inch e-readers new Go 7 and Go 7 Color Gen II retain their 150-to-300ppi e-ink screens while also adding e-pencil support and upgrading to Android 13 Although the company advertises the Go series devices as e-readers their full Google Play Store support makes them e-ink tablets in practice With the new Tab X C Boox has also updated its 13.3-inch pro-level tablet with a higher resolution color e-ink screen the new model is $50 cheaper than its predecessor TechSpot is a registered trademark and may not be used by third parties without express written permission TechSpot is represented by Future PLC. Learn about advertising opportunities It promises to offer paper-like visuals with vibrant colors Boox appears to be on a product-launching spree After recently dropping portable e-readers the company now has a new E Ink monitor dubbed Mira Pro (Color Version) It is a 25.3-inch monitor that claims to have paper-like visuals alongside rich colors The latest monitor is aimed at professionals and those who spend a lot of time on screens The massive 25.3-inch can be used as a primary or secondary screen and supports split-screen multitasking Then there’s adjustable dual-tone front lights to ensure readability in all lighting conditions and further making it eye-friendly The monitor further utilizes Boox Super Refresh technology that increases refresh rates alongside having four preset refresh modes “The Mira software allows further fine-tuning of Refresh Speed and Light Color Filter for truly customized viewing.” The Mira Pro (Color Version) is also port-friendly as it features HDMI The monitor supports all major operating systems like Windows an ergonomic stand for height adjustment alongside support for tilt and pivot modes for preferred comfortable viewing The VESA interface also enables the monitor to be mounted on a wall or desk your trusted companion in the world of Android As for pricing, the Boox Mira Pro (Color Version) is already available for purchase and retails at $1899.99 and every other gizmo connected to the internet you can find him on a long drive or lounging on the couch binge-watching a crime series you will then be prompted to enter your display name Not a lot of people will genuinely want an E Ink monitor and other tasks that benefit from a more comfortable giving you a fatigue-free display to rest your weary eyes One of the most interesting technologies used in displays is E Ink which has seen a revitalization in recent years by expanding well beyond simple eReaders into tablets On the extreme end of the spectrum, you can even find a E Ink monitor to place on your desk a premium 25.3-inch monitor that boasts an 1800p color E Ink screen but the Mira Pro is something very different and very cool.. The BOOX Mira Pro (Colore Version) is now available (when it's in stock) for $1,899.99 at BOOX premium E Ink monitor that boasts a 25.3-inch the monochrome original has been joined by a color version That's 16 grey levels and 4,096 colors behind its glass with a two-tone front light so you can work in all lighting conditions and a dedicated refresh button to help combat the ghosting so common with E Ink displays You can switch between multiple display modes allowing the Mira Pro to adjust its readability and refresh rate for the content on screen The included aluminum stand supports height but the Mira Pro also supports 75 x 75mm VESA mounts for added flexibility but same E Ink display that is its greatest draw is also its greatest drawback Most people will be frustrated more often than not with an E Ink display with even the most premium panels afflicted with washed out colors and constant ghosting For those who spend hours upon hours in front of a screen purely focused on staying productive E Ink may be exactly what they need to save their eyes and brain from the stress When the BOOX Mira Pro (Color Version) costs $1,899.99 at BOOX This fascinating monitor is now available to purchase but don't be surprised to find it out of stock (quantities are likely limited) If you need it, here's a quick recap on what E Ink is. This is a display technology commonly used in eReaders like the Amazon Kindle where it has reigned supreme for many years you can find it in a much wider variety of devices There's a reason E Ink displays are still niche outside of eReaders, though, and that's because of the downsides compared to backlit IPS LCD or self-lit OLED displays E Ink displays are generally terrible with moving content E Ink displays basically suspend countless particles (usually black and white) in fluid Running an electric current through those particles causes them to change alignment so the pixels can alternate between black and white but are more complex and considerably more expensive While preferrable over monochrome E Ink in some cases color E Ink displays also lack the vibrancy and dynamic range of basically any IPS LCD or OLED screen Please logout and then login again, you will then be prompted to enter your display name. That’s how Mira Costa boys’ volleyball coach Greg Snyder described his team’s performance Friday night following the latest chapter in a fierce rivalry between two of the top programs in the nation. The visiting Mustangs (20-1) took command early and never let up, sweeping Loyola 25-19, 25-18, 25-20 to establish themselves as the favorites to win the Southern Section’s highest division. Leading the way was Grand Canyon commit Thatcher Fahlbusch, a senior whose 12 kills came when his squad needed them most. The Mustangs avenged a loss in the finals of the Best of the West Tournament in San Diego two weeks ago — and ended a nightmarish losing streak against the Cubs. Mira Costa senior outside hitter Thatcher Fahlbusch celebrates after recording one of his 12 kills against Loyola on Friday night. (Steve Galluzzo / For The Times) “We served much better and got them out of system,” said Fahlbusch, whose younger brother Blake, a USC commit, was weakened by the flu but still had five kills for Loyola. “Our main strength is in numbers — they can’t key on one guy. We’d lost 11 in a row to them so we wanted to put an end to that.” Despite living in Manhattan Beach, the brothers decided when Thatcher was in eighth grade to go to Loyola, but he transferred after his sophomore year. He’s glad he made the switch — and so are his teammates. “It’s all love,” Thatcher said. “This is an awesome environment to play in.” Adding 12 kills, the last coming on the Mustangs’ third match point, was Mateo Fuerbringer, whose sister Charlie was a setter for Mira Costa and completed her freshman season at Wisconsin in December. Setter Andrew Chapin had 40 assists, UCLA commit Grayson Bradford (a senior transfer from Crespi) had 11 kills, and Alex Heins added seven kills and four blocks for the Mustangs, who had last beaten Loyola in the SoCal Regional Division I finals on June 12, 2021. “We wanted to win so bad,” Bradford said. “We brought the energy and we have so much trust in each other. No matter who it is, we believe we can put any ball away.” Loyola defeated Mira Costa three times last spring — winning the schools’ annual nonleague showdown, then sweeping the Mustangs in the Southern Section Division 1 finals and SoCal Regional finals — on its way to being crowned USA Today/AVCA national champion for a second straight season and the fourth time in school history. Snyder, who took the helm last season and guided Mira Costa to a 37-5 record, the Best of the West title and the Bay League championship, took a few moments to savor his first victory over Loyola and knows the rivals likely will meet again in the playoffs. The teams have met for the section title four times, Loyola winning in four sets in 2005 and 2010 and in three sets in 2024. Mira Costa prevailed in five sets in 2012. The Mustangs won the last of their eight section titles in 2021, sweeping Newport Harbor in the finals under previous coach Avery Drost. High School Sports In rivalry game, Royal defeats Simi Valley 2-1; Freshman Carlos Acuna strikes out 16 in Birmingham 4-0 win over Chatsworth “We haven’t been healthy all week, but take nothing away from them,” said Cubs coach Mike Boehle, who has piloted his alma mater to seven section titles since taking over in 1999. “It’s been four years since they beat us and they played out of their minds.” Nate Garrett led the way with nine kills and Simon Capps added seven for Loyola (12-3). Blue-and-white-clad supporters in the student section waved flags and chanted “Let’s go Cubs!” during introductions, but Mira Costa fans countered with “We can’t hear you!” in a timeout with their team holding a comfortable lead midway through the second set. California Subscribe for unlimited accessSite Map , opens new tab.Reporting by Krystal Hu in New York Anna Tong in San Francisco and Arsheeya Bajwa in Bengaluru; Editing by Shilpi Majumdar and Rosalba O'Brien Our Standards: The Thomson Reuters Trust Principles., opens new tab , opens new tab Browse an unrivalled portfolio of real-time and historical market data and insights from worldwide sources and experts. , opens new tabScreen for heightened risk individual and entities globally to help uncover hidden risks in business relationships and human networks. © 2025 Reuters. All rights reserved MIRA Pharmaceuticals (NASDAQ:MIRA) has announced positive results for its oral ketamine analog Ketamir-2 in a diabetic neuropathy animal model The study demonstrated significant reduction in neuropathic pain symptoms with some subjects achieving complete reversal to pre-diabetic baseline sensitivity The company is currently conducting a Phase I clinical trial at Hadassah Medical Center MIRA plans to initiate a Phase IIa trial in diabetic neuropathy patients by year-end with first human efficacy data expected in H1 2026 Ketamir-2 has shown superior performance compared to FDA-approved medications like pregabalin and gabapentin in preclinical studies it doesn't cause dissociative effects and offers better blood-brain barrier penetration The company is also developing a topical slow-release formulation and exploring applications for PTSD treatment MIRA Pharmaceuticals (NASDAQ:MIRA) ha annunciato risultati positivi per il suo analogo orale della ketamina in un modello animale di neuropatia diabetica Lo studio ha evidenziato una significativa riduzione dei sintomi del dolore neuropatico con alcuni soggetti che hanno raggiunto un completo ritorno alla sensibilità basale pre-diabetica L'azienda sta attualmente conducendo uno studio clinico di Fase I presso l'Hadassah Medical Center con completamento previsto per il quarto trimestre 2025 MIRA prevede di avviare uno studio di Fase IIa su pazienti con neuropatia diabetica entro la fine dell'anno con i primi dati di efficacia sull'uomo attesi nella prima metà del 2026 Ketamir-2 ha mostrato prestazioni superiori rispetto ai farmaci approvati dalla FDA come pregabalin e gabapentin negli studi preclinici non provoca effetti dissociativi e garantisce una migliore penetrazione nella barriera emato-encefalica L'azienda sta inoltre sviluppando una formulazione topica a rilascio lento ed esplorando applicazioni per il trattamento del disturbo da stress post-traumatico (PTSD) MIRA Pharmaceuticals (NASDAQ:MIRA) ha anunciado resultados positivos para su análogo oral de ketamina en un modelo animal de neuropatía diabética El estudio mostró una reducción significativa de los síntomas del dolor neuropático con algunos sujetos que lograron una reversión completa a la sensibilidad basal previa a la diabetes La compañía está llevando a cabo un ensayo clínico de Fase I en el Hadassah Medical Center con finalización prevista para el cuarto trimestre de 2025 MIRA planea iniciar un ensayo de Fase IIa en pacientes con neuropatía diabética antes de fin de año con los primeros datos de eficacia en humanos esperados para la primera mitad de 2026 Ketamir-2 ha demostrado un rendimiento superior en comparación con medicamentos aprobados por la FDA como pregabalina y gabapentina en estudios preclínicos no causa efectos disociativos y ofrece mejor penetración en la barrera hematoencefálica La empresa también está desarrollando una formulación tópica de liberación lenta y explorando aplicaciones para el tratamiento del trastorno de estrés postraumático (TEPT) MIRA Pharmaceuticals (NASDAQ:MIRA)는 당뇨병성 신경병증 동물 모델에서 경구용 케타민 유사체 Ketamir-2의 긍정적인 결과를 발표했습니다 MIRA는 연말까지 당뇨병성 신경병증 환자를 대상으로 2a상 시험을 시작할 계획이며 Ketamir-2는 전임상 연구에서 FDA 승인 약물인 프레가발린과 가바펜틴보다 우수한 성능을 보였습니다 전통적인 케타민과 달리 해리성 효과가 없으며 혈뇌장벽 투과율이 더 뛰어납니다 MIRA Pharmaceuticals (NASDAQ:MIRA) a annoncé des résultats positifs pour son analogue oral de la kétamine dans un modèle animal de neuropathie diabétique L'étude a démontré une réduction significative des symptômes de la douleur neuropathique certains sujets retrouvant une sensibilité de base équivalente à celle d'avant le diabète L'entreprise mène actuellement un essai clinique de phase I au centre médical Hadassah dont l'achèvement est prévu pour le quatrième trimestre 2025 MIRA prévoit de lancer un essai de phase IIa chez des patients atteints de neuropathie diabétique d'ici la fin de l'année avec les premières données d'efficacité humaine attendues au premier semestre 2026 Ketamir-2 a montré des performances supérieures par rapport aux médicaments approuvés par la FDA tels que la prégabaline et la gabapentine lors des études précliniques Contrairement à la kétamine traditionnelle il ne provoque pas d'effets dissociatifs et offre une meilleure pénétration de la barrière hémato-encéphalique L'entreprise développe également une formulation topique à libération lente et explore des applications pour le traitement du trouble de stress post-traumatique (TSPT) MIRA Pharmaceuticals (NASDAQ:MIRA) hat positive Ergebnisse für seinen oralen Ketamin-Analogon Ketamir-2 in einem Tiermodell der diabetischen Neuropathie bekannt gegeben Die Studie zeigte eine signifikante Verringerung der neuropathischen Schmerzsymptome wobei einige Probanden eine vollständige Rückkehr zur prädiabetischen Basissensitivität erreichten Das Unternehmen führt derzeit eine Phase-I-Studie am Hadassah Medical Center durch deren Abschluss für das vierte Quartal 2025 erwartet wird bis Jahresende eine Phase-IIa-Studie bei Patienten mit diabetischer Neuropathie zu starten wobei erste Wirksamkeitsdaten am Menschen für das erste Halbjahr 2026 erwartet werden Ketamir-2 zeigte in präklinischen Studien eine überlegene Leistung im Vergleich zu von der FDA zugelassenen Medikamenten wie Pregabalin und Gabapentin Im Gegensatz zu herkömmlichem Ketamin verursacht es keine dissoziativen Effekte und bietet eine bessere Penetration der Blut-Hirn-Schranke Das Unternehmen entwickelt zudem eine topische Slow-Release-Formulierung und erforscht Anwendungen zur Behandlung von PTBS MIRA's preclinical data for Ketamir-2 represents an important development in the diabetic neuropathy space where current treatments offer efficacy for many patients The animal model demonstrated significant reduction in neuropathic pain symptoms with some subjects achieving complete symptom reversal to baseline sensitivity - a particularly encouraging outcome Ketamir-2's differentiated profile is noteworthy: it's an oral ketamine analog without the dissociative/psychedelic effects of traditional ketamine and bypasses P-glycoprotein transport potentially increasing blood-brain barrier penetration Preclinical data suggests it outperforms FDA-approved pregabalin and gabapentin current standard-of-care options that provide only modest relief for many patients The clinical development appears on track with Phase I dosing underway and completion expected in Q4 2025 followed by Phase IIa in diabetic neuropathy The FDA's designation of neuropathic pain as high-priority could potentially accelerate approval pathways investors should recognize that preclinical efficacy often doesn't translate to humans and the real value inflection points remain the Phase I safety data and eventually Phase II efficacy results in 2026 The diabetic neuropathy market represents substantial opportunity affecting 28-55% of diabetes patients with $10+ billion in associated annual costs but MIRA will need clinical validation to capture this potential MIRA's strategic positioning with Ketamir-2 appears well-aligned with multiple healthcare trends and market opportunities The company is targeting diabetic neuropathy - a condition with high prevalence affecting up to 55% of diabetic patients worldwide and representing substantial unmet need given the limitations of current therapies Their approach addresses three convergent market dynamics: 1) increasing diabetes prevalence driving neuropathy cases 2) growing demand for non-opioid pain solutions amid the ongoing opioid crisis and 3) FDA prioritization of neuropathic pain treatments through potential accelerated pathways The company's pipeline expansion through the pending SKNY Pharmaceuticals acquisition adds strategic diversification with SKNY-1 targeting obesity and smoking cessation - both representing massive markets with satisfactory treatment options This multi-indication strategy across both Ketamir-2 (neuropathy/PTSD) and the acquired SKNY-1 asset creates multiple potential value-creation pathways While the positive preclinical results strengthen MIRA's narrative the most critical milestones remain ahead: Phase I completion in Q4 2025 and Phase IIa efficacy data in 2026 The development of a topical formulation could further expand addressable markets by providing localized treatment with minimized systemic exposure For a company with $14.8 million market cap successful execution across these programs could represent significant upside potential Ketamir-2 Demonstrates Strong Efficacy in Diabetic Neuropathy Model with Some Subjects Achieving Complete Symptom Reversal MIAMI, FLORIDA / ACCESS Newswire / April 16 a clinical-stage pharmaceutical company focused on developing novel therapeutics for neurologic and neuropsychiatric disorders today announced compelling data demonstrating the efficacy of the oral ketamine analog in a validated animal model of diabetic neuropathy Type 2 diabetes was induced in rats using a high-fat diet combined with a low dose of Streptozotocin (STZ) This resulted in hyperglycemia and neuropathic symptoms most diabetic rats exhibited sensory hypersensitivity Treatment with Ketamir-2 led to a significant reduction in neuropathic pain symptoms with some animals returning completely to pre-diabetic baseline sensitivity "Millions of patients with diabetic neuropathy are left with limited often ineffective treatment options," said Erez Aminov we're aiming to offer a non-opioid alternative that's not only safer but potentially more effective We're currently advancing our Phase I study and plan to initiate a Phase IIa trial in diabetic neuropathy patients by year-end Given that the FDA has designated neuropathic pain as a high-priority area for Fast Track and Breakthrough Therapy pathways we believe Ketamir-2 is uniquely positioned to meet this urgent need and unlock significant clinical and commercial value." Translational Data Strengthens Clinical Momentum These results build upon prior preclinical studies using other neuropathy animal models where orally administered Ketamir-2 outperformed FDA-approved neuropathic pain medications such as pregabalin and gabapentin while also demonstrating a favorable safety profile Ketamir-2 does not induce dissociative or psychedelic effects and is not a substrate for P-glycoprotein (P-gp) allowing for more efficient penetration across the blood-brain barrier MIRA has already begun dosing and recruitment in its Phase I clinical trial at Hadassah Medical Center in Jerusalem The study is progressing smoothly and on schedule placebo-controlled trial is assessing safety and pharmacokinetics in healthy volunteers with a Phase IIa study in diabetic neuropathy patients planned to follow "The strong alignment between this model and human pathology together with results obtained with other experimental models gives us a high degree of scientific confidence as we move forward," said Dr "Seeing such robust responses in a validated model of diabetic neuropathy reinforces the potential clinical impact of Ketamir-2 and helps guide the path ahead." Diabetic neuropathy affects between 28% to 55% of patients with diabetes and remains one of the most prevalent and debilitating complications associated with the disease As global diabetes rates continue to climb the number of patients suffering from chronic neuropathic pain is expected to rise sharply placing an increasing burden on healthcare systems worldwide the demand for non-opioid therapies is growing rapidly driven by the ongoing opioid crisis and heightened regulatory scrutiny Ketamir-2's non-addictive profile and lack of dissociative side effects position it as a strong candidate in this emerging treatment landscape The economic burden of diabetic neuropathy is also substantial. A study published in Drugs & Aging estimated that diabetic peripheral neuropathy contributes more than $10 billion annually in direct medical costs in the U.S. alone. This includes costs related to increased hospitalizations, physician visits, disability, and lost productivity.(Gordois et al., Drugs Aging. 2003) Importantly, the FDA has previously identified neuropathic pain as a high-priority area for accelerated development, granting Fast Track and Breakthrough Therapy designations to compounds that demonstrate potential to improve outcomes over standard treatments.(FDA Guidance for Industry - Expedited Programs for Serious Conditions) Ketamir-2 may be positioned to meet key criteria for future regulatory acceleration MIRA anticipates initiating its Phase IIa clinical trial in diabetic neuropathy by the end of 2025 with first human efficacy data expected in the first half of 2026 development of a topical slow-release formulation of Ketamir-2 continues aimed at providing localized pain relief with minimized systemic exposure MIRA is actively conducting ongoing studies assessing the efficacy of Ketamir-2 in models of post-traumatic stress disorder (PTSD) a serious and underserved neuropsychiatric condition MIRA remains committed to unlocking the full therapeutic potential of Ketamir-2 across multiple indications MIRA is also pleased to report continued progress on the pending acquisition of SKNY Pharmaceuticals a move that strengthens MIRA's strategic pipeline MIRA is highly enthusiastic about the promise of SKNY-1 a next-generation oral therapeutic in development for the treatment of obesity and smoking cessation two major public health challenges that lack scalable (NASDAQ:MIRA) is a clinical-stage pharmaceutical development company with two neuroscience programs targeting a broad range of neurologic and neuropsychiatric disorders patent-pending oral ketamine analog under investigation to treat neuropathic pain (NP) major depressive disorder with suicidal ideation (MDD-SI) MIRA's novel oral pharmaceutical marijuana analog is currently under investigation for treating adult patients suffering from anxiety and cognitive decline often associated with early-stage dementia MIRA-55 could mark a significant advancement in addressing various neuropsychiatric Drug Enforcement Administration's scientific review concluded that both Ketamir-2 and MIRA-55 would not be considered controlled substances or listed chemicals under the Controlled Substances Act and its governing regulations Additional information about MIRA Pharmaceuticals is available at www.mirapharmaceuticals.com Cautionary Note Regarding Forward-Looking Statements This press release and the statements of MIRA's management related thereto contain "forward-looking statements," which are statements other than historical facts made pursuant to the safe harbor provisions of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 These statements may be identified by words such as "aims," "anticipates," "believes," "could," "estimates," "expects," "forecasts," "goal," "intends," "may," "plans," "possible," "potential," "seeks," "will," and variations of these words or similar expressions that are intended to identify forward-looking statements Any statements in this press release that are not historical facts may be deemed forward-looking statements regarding the anticipated benefits of the acquisition transaction and claims regarding SKNY-1 Any forward-looking statements in this press release are based on Mira's current expectations and projections only as of the date of this release and are subject to a number of risks and uncertainties (many of which are beyond MIRA's control) that could cause actual results to differ materially and adversely from those set forth in or implied by such forward-looking statements These and other risks concerning MIRA's programs and operations are described in additional detail in the Annual Report on Form 10-K for the year ended December 31 which are on file with the SEC at www.sec.gov and MIRA's website at https://www.mirapharmaceuticals.com/investors/sec-filings MIRA explicitly disclaims any obligation to update any forward-looking statements except to the extent required by law Helga Moya info@mirapharma.com(786) 432-9792 Already have an account? Login The Mustangs held Santa Barbara scoreless for more than five minutes to start the quarter and came away with a 61-40 victory Saturday night. Eneasi Piuleini scored 19 points, McCarthy Bedner had 16 points and Jacob De Armas 12 points for a Mira Costa team that is 29-3 and will play Los Alamitos for the Division 1 championship next Saturday at Toyota Arena in Ontario. “I love this group of seniors and love this team,” Mira Costa coach Neal Perlmutter said. Eneasi Piuleini scored 19 points in Mira Costa’s playoff win over Santa Barbara. (Craig Weston) It’s a neighborhood team whose players had to wait their turn and come up from the bottom and deliver when the opportunity presented itself. De Armas and Piuleini started as freshman junior varsity players before becoming senior stars. Each had dunks that energized Mira Costa’s home crowd. “Good things take time to marinate,” Perlmutter said. “It feels good the guys who stuck around were rewarded.” Mira Costa’s defense held Santa Barbara’s Luke Zuffelato to seven points and only three shots in the first half. He finished with 16 points. Franklin 69, South East 65: Adam Sanchez scored 23 points and RJ Sanders 22 points to help No. 13-seeded Franklin advance in the City Section Division II playoffs. Sun Valley Poly 52, LACES 35: The Parrots advanced to the City Division I semifinals. JD Wyatt scored 28 points. Grant 69, El Camino Real 52: Champ Merrill scored 22 points to help the Lancers become the second East Valley League team in the City Division I semifinals. Eric Sondheimer is the prep sports columnist for the Los Angeles Times. He has been honored seven times by the California Prep Sportswriters Assn. for best prep sports column. Today she announced that indeed she is the CEO of a new public benefit corporation called Thinking Machines Lab Its mission is to develop top-notch AI with an eye toward making it useful and accessible Murati believes there’s a serious gap between rapidly advancing AI and the public’s understanding of the technology Even sophisticated scientists don’t have a firm grasp on AI’s capabilities and limitations Thinking Machines Lab plans to fill that gap by building in accessibility from the start It also promises to share its work by publishing technical notes Underpinning this strategy is Murati’s belief that we are still in the early stages of AI, and the competition is far from closed. Though it occurred after Murati began planning her lab, the emergence of DeepSeek—which claimed to build advanced reasoning models for a fraction of the usual cost—vindicates her thinking that newcomers can compete with more-efficient models Thinking Machines Lab believes that upscaling the capabilities of its models to the highest level is important to filling the gap it has identified even with the efficiencies of the DeepSeek era Though Thinking Machines Lab hasn’t shared its funding partners yet it’s confident that it will raise the necessary millions Murati’s pitch has attracted an impressive team of researchers and scientists Those include former VP of research Barret Zoph (who is now CTO at Thinking Machines Lab) multimodal research head Alexander Kirillov The lab's chief scientist will be John Schulman a key ChatGPT inventor who left OpenAI for Anthropic only last summer Others come from competitors like Google and Mistral AI The team moved into an office in San Francisco late last year and has already started work on a number of projects Though it’s not clear what its products will look like Thinking Machines Lab indicates that they won’t be copycats of ChatGPT or Claude but AI models that optimize collaboration between humans and AI—which Murati sees as the current bottleneck in the field American inventor Danny Hillis dreamed of this partnership between people and machines over 30 years ago Hillis built a super computer with powerful chips running in parallel—a forerunner to the clusters that run AI today Thinking Machines declared bankruptcy in 1994 In your inbox: Get Plaintext—Steven Levy's long view on tech Federal judge allows DOGE to take over $500 million office building for free Big Story: The quantum apocalypse is coming Bluesky can’t take a joke Summer Lab: Explore the future of tech with WIRED It is the essential source of information and ideas that make sense of a world in constant transformation The WIRED conversation illuminates how technology is changing every aspect of our lives—from culture to business The breakthroughs and innovations that we uncover lead to new ways of thinking Thinking Machines Lab has hired a bunch of leaders from OpenAI by Kylie Robison ex-CTO Mira Murati vanished from public view to start something new she is ready to share some details about what she’s working on Her new AI startup is called Thinking Machines Lab, and while the specifics of what it plans to release are still under wraps, the company says its goal is “to make AI systems more widely understood, customizable and generally capable.” The startup also promises at least some level of public transparency by pledging to regularly publish technical research and code. In a press release shared with The Verge, the company suggests that it’s building products that help humans work with AI, rather than fully autonomous systems. “We’re building a future where everyone has access to the knowledge and tools to make AI work for their unique needs and goals,” says the press release. I’d love to chat. You can reach me securely on Signal @kylie.01 or via email at kylie@theverge.com. Please enable JS and disable any ad blocker We use cookies to personalize content and ads and to analyze our traffic and improve our service At a time when art installations are often designed for Instagram appeal Mira Dayal’s work quietly pushes in the opposite direction (2021) at Spencer Brownstone Gallery centered around a one-to-one topographical map of the gallery floor A Hairline Crack (2019) at Gymnasium consisted of trompe-l’œil cracks drawn on the gallery walls Anagen (2019) contained dangling wisps of the artist’s hair sewn into drop-ceiling tiles installed at Lubov Installations such as these eschew bold visuals and instead favor the physical gallery experience People in the arts often speak about artist’s artists nor that it sometimes incorporates language into its visual presentation It’s not even that she also works as an editor and critic tactile ways: the downy hairs that make the gallery ceiling appear like an eerie organism; the graphite-covered floor that’s slick to walk on Dayal practices a materials-minded conceptualism and it’s unlike most art you see on Instagram or experience at a gallery Louis Bury How do you understand your work in relation to minimalism Mira Dayal I’m drawn to the reduced geometry of minimalist work which might come from always having loved math and toying with systems and shapes I ask myself questions such as: Is this doing what I want it to do I appreciate how the physical presence of good minimalist or conceptualist work adds something to its premise and does weird unexpected things when you get in the room with it LB How do these considerations manifest for you at the level of the larger exhibition MD I try to combine different elements into something like an equation that I keep adding to talks about “thinking algebraically” in the studio We both have these algorithms for our work and I think a lot about different possible logics when putting together a larger exhibition All of this leads me to make work that tends to be site-specific and laboriously hand-produced LB Those qualities were prominent in your In That Empire where you covered the entire gallery floor with graphite MD That show ended up having lots of perceptual and physical effects that I couldn’t have anticipated The premise of a one-to-one drawing that’s also a map of the gallery space was ultimately framed by the one-paragraph Jorge Luis Borges story that is the show’s title But this is a good example of how ideas fit together into a larger exhibition I had been thinking about several different things—the role of annotation in Glenn Ligon’s Condition Report how to make a drawing that was also sculptural mapping technologies and aerial views—and the Borges conceit helped these variables cohere LB Your current body of work explores the relations between sculptures How are you fitting those variables together MD This body of work is a bit different because it began with the materials rather than the ideas I was figuring out a sculptural vocabulary in steel and the objects I was drawn to representing were vernacular things I appreciated how these playful objects could be easily rendered in the planes and lines of steel sheets and rods but the sculptures also transmit an intensity in steel And I became interested in how methods of assembling or disassembling paper goods might carry over into steel paper clips and staples are basic metal units to attach paper sheets I started making my own staples to use as connecting tools and making chains of paper clips that attach only to each other LB What’s the relationship between the maquettes and the larger works The maquettes often feel like works in their own right MD The maquettes can look very different from the larger sculptures and are as much about process as about studying a form I often make a larger version first and then play with a specific material problem at maquette scale The larger works are more about seeing what happens when you blow up these ordinary objects to an exaggerated size in a durable This changes the way you encounter them in space; new associations emerge Can you talk about the absence of color in your work MD The only color is that of the materials Not adding color allows the works to remain more open-ended I’m interested in steel’s associations with infrastructure architecture; these sculptures are fragments of larger systems Keeping their surfaces raw allows viewers to glean more information about how the works were made I let the material speak and try not to add visual information that feels superficial to the ideas LB I love how your work plays with different registers of opacity and legibility I think it’s important for the work to have layers—something to draw you in and The work feels like a puzzle for me to understand and hand to the viewer—here’s this—who uses the information provided LB Your work as a critic and editor gives you lots of experience on the viewer side of things How does that background inform your studio practice being a critic and editor means you see lots of shows and talk to lots of artists I absorb a lot and try to make work that I’d be excited to see Editing is also very responsive in that you receive someone else’s text and help bring it into another form of itself I think part of my task as an artist is to respond LB What about your artworks that incorporate language into their visual presentation when I was invited to collaborate with Marina Kassianidou gave us the prompt “a trembling line.” I was thinking about ambiguous images They actually started out not just as a security measure but as a way to make legible texts that machine readers couldn’t read They were an early instance of crowdsourced free labor I got interested in the translations involved: from physical text and then back to paper through my ink drawings They keep getting fragmented and reassembled I’ve experimented with these forms in different mediums which recalls movable type and plates for printing The plasma-cutting technique creates further distortions—rainbow-like heat marks slag—which is a good example of the material doing something to the idea LB What you’re saying brings to mind concrete poetry which is a genre concerned with material instantiations of language MD I’m interested in work that reveals itself slowly What might initially seem like a room full of flat objects starts to yield more information the more you spend time with it The image that comes to mind is a pop-up greeting card: it’s folded-up in an envelope where your initial confusion leads to epiphanies where your initial bedazzlement leads to curiosity about the work’s nuances How do your works’ titles factor into this dynamic MD I often choose matter-of-fact titles because they give you something concrete to hold on to if you don’t know what the work is to avoid dictating the viewer’s experience of the work I always have working titles in my head; sometimes I wish I could give each work ten titles at once Mira Dayal: conjunctions is on view at Fuller Rosen Gallery in Philadelphia until March 16; Mira Dayal: Steel Model of Paper Copy of Desk Top with Pencil Groove is on view at Spencer Brownstone Gallery in New York City until April 26 Louis Bury is the author of The Way Things Go and Exercises in Criticism and a professor of English at Hostos Community College ShareSaveComment@font-face{font-family: "Schnyder"; src: url("https://i.forbesimg.com/assets/fonts/schnyders/schnyders-bold-webfont.woff2") format("woff2") url("https://i.forbesimg.com/assets/fonts/schnyders/schnyders/schnyders-bold-webfont.woff") format("woff"); font-weight: 700; font-style: normal;} @font-face{font-family: "Merriweather"; src: url("https://i.forbesimg.com/assets/fonts/merriweather/merriweather-bold-webfont.woff2") format("woff2") url("https://i.forbesimg.com/assets/fonts/merriweather/merriweather-bold-webfont.woff") format("woff"); font-weight: 700; font-style: normal;} @font-face{font-family: "Euclid"; src: url("https://i.forbesimg.com/assets/fonts/euclidcircularb/euclidcircularb-bold-webfont.woff2") format("woff2") url("https://i.forbesimg.com/assets/fonts/euclidcircularb/euclidcircularb-bold-webfont.woff") format("woff"); font-weight: 700; font-style: normal;} @font-face{font-family: "Schnyder"; src: url("https://i.forbesimg.com/assets/fonts/schnyders/schnyders-light-webfont.woff2") format("woff2") url("https://i.forbesimg.com/assets/fonts/schnyders/schnyders-light-webfont.woff") format("woff"); font-weight: 400; font-style: normal;} @font-face{font-family: "Merriweather"; src: url("https://i.forbesimg.com/assets/fonts/merriweather/merriweather-regular-webfont.woff2") format("woff2") url("https://i.forbesimg.com/assets/fonts/merriweather/merriweather-regular-webfont.woff") format("woff"); font-weight: 400; font-style: normal;} @font-face{font-family: "Euclid"; src: url("https://i.forbesimg.com/assets/fonts/euclidcircularb/euclidcircularb-regular-webfont.woff2") format("woff2") #article-stream-0 .headline-embed .color-accent{color: #000000;} #article-stream-0 .headline-embed.bg-accent #article-stream-0 .headline-embed .bg-accent{background-color: #000000;} #article-stream-0 .headline-embed.color-base #article-stream-0 .headline-embed .color-base{color: #FFFFFF;} #article-stream-0 .headline-embed.bg-base #article-stream-0 .headline-embed .bg-base{background-color: #FFFFFF;} #article-stream-0 .headline-embed.font-base #article-stream-0 .headline-embed .font-base{} #article-stream-0 .headline-embed.font-size #article-stream-0 .headline-embed .font-size{font-size: 54px;} #article-stream-0 .subhead-embed.color-accent #article-stream-0 .subhead-embed .color-accent{color: #333333;} #article-stream-0 .subhead-embed.bg-accent #article-stream-0 .subhead-embed .bg-accent{background-color: #333333;} #article-stream-0 .subhead-embed.font-accent #article-stream-0 .subhead-embed .font-accent{font-family: Euclid,"Noto Sans","Droid Sans","Helvetica Neue",Corbel,Helvetica,Arial,sans-serif;} #article-stream-0 .subhead-embed.font-size #article-stream-0 .subhead-embed .font-size{font-size: 26px;} #article-stream-0 .subhead3-embed.color-body #article-stream-0 .subhead3-embed .color-body{color: #333333;} #article-stream-0 .subhead3-embed.color-body-border{border-top-color: rgba(51,51,51 #article-stream-0 .subhead3-embed .color-body-border{border-top-color: rgba(51,51,51 0.8);} .bg-body{background-color: #333333;} #article-stream-0 .subhead3-embed.font-accent #article-stream-0 .subhead3-embed .font-accent{font-family: Euclid,"Noto Sans","Droid Sans","Helvetica Neue",Corbel,Helvetica,Arial,sans-serif;} #article-stream-0 .quote-embed.color-accent #article-stream-0 .quote-embed .color-accent{color: #FFFFFF;} #article-stream-0 .quote-embed.bg-accent #article-stream-0 .quote-embed .bg-accent{background-color: #FFFFFF;} #article-stream-0 .quote-embed.color-base #article-stream-0 .quote-embed .color-base{color: #000000;} #article-stream-0 .quote-embed.bg-base #article-stream-0 .quote-embed .bg-base{background-color: #000000;} #article-stream-0 .quote-embed.font-accent #article-stream-0 .quote-embed .font-accent{font-family: Schnyder,"Noto Sans","Droid Sans","Helvetica Neue",Corbel,Helvetica,Arial,sans-serif;} #article-stream-0 .quote-embed.font-size p #article-stream-0 .quote-embed .font-size p{font-size: 36px;}Welcome back to The Prompt announced her new venture called Thinking Machine Labs where she plans to build accessible AI systems code and papers and collaborate with the broader community indicating it plans to open source its work Musk said the company’s mission is to “understand the universe…to figure out what’s going on where are the aliens and what’s the meaning of life.” Grok-3 has yet not been independently evaluated and is only available to paying users Forbes sent a cease and desist letter to Perplexity AI legal company Luminance which helps customers like AMD and National Grid generate has raised $75 million in series C funding Chip startup Encharge AI has raised $100 million in a series B funding led by Tiger Global CEO Naveen Verma started the company out of a lab in Princeton where he worked on designing architecture for hardware that would help run large language models more compute and energy efficiently Verma says the chips allow AI models to run locally on devices such as personal computers Elon Musk’s surprise bid for the nonprofit controlling artificial intelligence behemoth OpenAI did exactly what he wanted it to Announced as OpenAI CEO Sam Altman and other business and world leaders convened in Paris for a global AI summit the unsolicited $97.4 billion offer for the nonprofit refocused the world’s attention on Musk and his efforts to block OpenAI’s transition to a for-profit company An irked Altman quickly dismissed Musk’s offer and sources close to OpenAI say it’s hard to imagine it going anywhere Musk has likely caused a headache for Altman who is orchestrating the company’s transition to a for-profit venture He’s attempted to forcefully raise the nonprofit price – which would make it harder for OpenAI to justify paying anything less citing a 25% stake and the company’s valuation at time Altman faces pressure to sell the nonprofit for at least what Musk is asking making it seem like he’s lowballing his own company to reduce share dilution “The important part here is that if [the board] doesn't take it then they've made clear that they think the assets Musk is trying to buy are worth more than $97 billion,” a person familiar with the company told Forbes “So if the for-profit tries to buy them later the nonprofit will have to get more than that — otherwise the board is likely in breach of their fiduciary duties.” Read the full story on Forbes MUMBAI: Two men have been arrested for cheating 1,375 people of ₹20.60 crore by promising them an income of ₹55,000 to ₹75,000 per month if they became part of a car-rental business The arrests were made by the Kashimira police in Mira Road on April 29 Two held for defrauding 1,375 people in car-rental scam Police have seized 246 cars valued at around ₹25 crore from the accused identified as Sandeep Kandalkar aka Raju Rajiv Joshi and Sachin Tetagure both residents of Dapoli in Rantagiri district would tempt people to invest in the supposed rental car business by telling them this was a pick-up and drop service from the airport and ports such as the Jawaharlal Nehru Port Authority The individuals were told they would earn ₹55,000 to ₹75,000 per month if they either invested in the business or rented their own cars for the pick-up and drop service The accused also used the money they collected to buy expensive cars and SUVs “The accused thus collected a total of ₹20.60 crore from 1,375 people,” said a police officer the scamsters initially deposited the promised sums into their bank accounts but soon started to default on the payments The police officer said 246 vehicles have been seized from Mumbai and surrounding areas based on information provided by the two arrested accused The seized vehicles include cars such as the Innova Crysta Police have also identified some associates of the arrested accused They are Divyata Mhatre (26) and Rohan Mhatre (35) both residents of Mira Road; Pravin Telang (44) a Bhayander resident; Vaishali Dhuri (47) from Charkop in Mumbai; Nilesh Shinde (38) a resident of Mantuga East; and Babu Maruti Awad (49) Police said the accused have been charged with cheating and breach of trust under the Bharatiya Nyaya Sanhita and additionally for being members of an organised crime syndicate as the investigation revealed that financial fraud had been committed over a long period of time and stars in—she spends a bit of time sitting at a bedroom vanity Staring through the pretend mirror to the audience she muses and frets about two themes that preoccupy and amuse her character: disgust and vanity These two conditions of self-regard are like flip images of one another “I wanted to explore that—the counterbalance of vanity to disgust,” Pickus said In the play she has moments when she exudes confidence and I’m really smart!” she said in an interview a couple weeks before the show “And then I hate everything about myself and my body Her character worries at different times that she is “intolerable,” “impenetrable”—frighteningly The play is titled mint frappe, and Pickus’s character is called M. The color green makes a dominant impression, both in the language M uses and on the stage. Pickus designed, built, and painted the set—work she began in an independent study last fall with Assistant Professor of Theater Germán Cárdenas-Alaminos the stage has a floral decor: its floor is lime “Green is incredibly important to the play It is also the color for decomposition and rotten food M speaks her thoughts and fantasies out loud (she calls the ones that come at night her “nightly pensivities,” especially the ones where she constructs “little life scenes centering on the core theme of your crush liking you back).” She also occasionally takes a call from a friend with whom she laments about her unrequited crush Pickus began thinking about the play last winter ruminating over the many ideas she had written down in journals and for class essays—about disgust and vanity and disease. Though she was in the very early stages of creativity when her imagination was full but she had no clear route to a plot or script Bowdoin’s theater department got behind her “I wanted a way to explore those themes and had the very, very vague idea that maybe in the future this would become a play,” Pickus said. “I reached out to Professor Killeen [Abigail Killeen but would you have any interest in advising a summer research project where I work on these and dramatize them?' And she was super on board.” I wanted to explore that—the counterbalance of vanity to disgust,” Pickus said she has moments when she exudes self-love and confidence Pickus received a fellowship from Bowdoin to live on campus over the summer and work on the play. In the fall, she was approved to continue developing her show and was awarded funding with a Fall Research Award.  Killeen said that advising Pickus has been “inspiring and joyful.” She found an easy balance between applying her expertise without imposing her own taste or sensibilities due to “Mira's strong but malleable vision for the play always carries the day,” she wrote in an email.  She also praised Pickus's mint frappe for the way it translates personal experiences into the universal “and how it highlights Mira’s intellect Pickus began her work last summer by drafting a series of autobiographical essays She is up-front about the source for much of that dissatisfaction: she was diagnosed with a painful chronic condition her sophomore year When she first experienced the mysterious affliction she was in so much agony she couldn’t walk “There is also a kind of anger at the heart of the play,” Pickus said “for issues that go unnoticed and don’t have a place to be sorted out.” The next phase of her work had her turning to the writers who had initially galvanized her exploration of these themes. She experienced a moment of recognition her sophomore fall when she took the class Mean Women Writers with Marilyn Reizbaum Bowdoin's Harrison King McCann Professor of English the class read Katherine Mansfield’s short repulsive story “Je ne parle pas français,” and the theorist Sianne Ngai’s book “I was very interested in disgust academically and reading a lot of female writers working with disgust and I was also interested in the female experience of ‘I hate my body!,’” Pickus said she takes aim at the self-help industry directed at women and its weak platitudes look in the mirror and recite the affirmations: I am strong you have to before you can love someone else,' or so the saying goes But I know a lot of self-hating people in relationships a lot of people who in fact don't love themselves and so have secured that relationship to have someone else do the loving for them no different than manufactured in China.” Though Pickus started the playwriting process unsure of the outcome—“maybe a play will come out of this maybe it won’t,” she told herself—by early August she had finished a first draft of a script it would have been a good experience reading and writing,” she said I will bury these essays and no one will ever read them.’” one that will be performed April 17 and 18 in Wish Theater to share this thing that doesn’t have a place anywhere else,” Pickus said “I expect a lot of my female peers will feel very seen.”  is aiming to raise a $1 billion funding round at a roughly $9 billion valuation people familiar with the matter told Business Insider A spokesperson for Murati declined to comment A $9 billion valuation is unusually high for a startup less than a year old, but investors have been eager to back AI startups especially those founded by former OpenAI employees a move that sparked turmoil within the company In a blog post Murati positioned the startup as an artificial intelligence research and product lab focused on making AI more accessible we're building Thinking Machines Lab to make AI systems more widely understood customizable and generally capable," the post said Murati has recruited a long list of engineers and AI researchers from her former employer OpenAI Dario and Daniela Amodei also worked at OpenAI and founded Anthropic in 2021 known for its smartphone-sized Palma e-reader is releasing its first-ever desktop monitor with a color E ink display The Mira Pro (Color) is a new version of the existing Mira Pro which debuted in 2023 with a more standard black-and-white E ink screen Boox's new monitor utilizes the Kaleido 3 color ePaper tech, similar to the display on the Amazon Kindle Colorsoft According to Boox, the display comes with 16 levels of grayscale and 4096 colors. It's far less than the 50,000 colors available on the Remarkable Paper Pro tablet one of our complaints about the Remarkable is its slow refresh rate It features a faster refresh rate with four customizable display modes that balance image quality and performance "This monitor offers soft colors, making it ideal for tasks that require color differentiation such as reviewing color-coded dashboards, analyzing data, or working with complex graphic," a press release reads A US customer can expect a price closer to $4654.98 Boox notes that the monitors ship from China and that "some countries may levy tariffs on imported goods." that means a US customer can expect a price closer to $4654.98 thanks to the current 145% tariff being levied against Chinese imported goods by the Trump administration this monitor probably won't work for content editors gamers or people who watch shows or movies on their monitors for professionals diving deep in data entry or writing especially if you deal with regular eye strain He’s been involved in tech since 2011 at various outlets and is on an ongoing hunt to build the easiest to use home media system you are more than welcome to discuss board games or disc golf with him.  you will then be prompted to enter your display name.