Metrics details To characterize the use of olodaterol and indacaterol in clinical practice and to quantify the off-label use in asthma Drug utilization study of new users of olodaterol or indacaterol between 2014 and 2017 in the PHARMO Database Network in the Netherlands and the IMS Real-World Evidence Longitudinal Patient Database panels in France On-label use was defined as use among adults with a recorded diagnosis of COPD Off-label use was defined as use among adults with a recorded diagnosis of asthma without a recorded diagnosis of COPD or as use among patients aged ≤18 years Potential off-label use was defined as no recorded diagnosis of either COPD or asthma The study included 4,158 new users of olodaterol and 9,966 new users of indacaterol Prevalence of off-label use ranged from 3.5% for both drugs to 12.4% for olodaterol and 11.9% for indacaterol Prevalence of on-label use ranged from 47.8% to 77.7% for olodaterol and from 28.7% to 70.1% for indacaterol The remaining new users of olodaterol and indacaterol were classified as potential off-label users with prevalence ranging from 17.3% to 48.6% for olodaterol and from 20.5% to 66.6% for indacaterol This study provides no evidence of a major concern in Europe for olodaterol or indacaterol for off-label use in asthma or for pediatric use The main objectives of the study were to describe the baseline characteristics of patients initiating on olodaterol and to quantify off-label use of olodaterol to treat asthma in three countries in Europe To provide a meanin gful context for the results we also describe characteristics and off-label use of indacaterol the other LABA not indicated to treat asthma The IMS RWE LPD panels include EMRs from routine clinical practice from a subset of GPs (GP panel) and pulmonologist (Pulmonologist panel) in France The study period started on the date of olodaterol launch in each country and ended on the latest date the data were available at the time of each final data extraction The study periods included in the final data extraction for each data source were from March 1 in PHARMO and the Danish population registers and from October 1 The time periods vary by data source due to time lag in availability of data to researchers The study was carried out in accordance with relevant guidelines and regulations The study protocol was approved by the Institutional Review Board (IRB) and by the scientific and ethic committees required by each database The need for informed consent was waived by the IRB Patients were included in the study if they fulfilled all the following criteria: (1) received a first prescription/dispensing for single-agent formulations of olodaterol or indacaterol during the study period (new users with no prescriptions/dispensings ever before) and (2) had at least 12 months of continuous enrolment in the study health care databases preceding the index date the date of the first prescription/dispensing for olodaterol or indacaterol Because the study aimed to assess the use of olodaterol and indacaterol in regular clinical practice individuals with missing or implausible (e.g. age over 120 years) values for age or sex were excluded Review of a sample of 100 patient profiles per drug in each data source was performed to confirm the appropriate performance of the algorithm to identify COPD and asthma and that the appropriate time windows were being used New users of olodaterol and new users of indacaterol were characterized at the index date according to demographic variables (age and sex), lifestyle characteristics as available in each data source (Supplemental Table 3) (smoking respiratory and nonrespiratory comorbidities Covariates were ascertained based on all information available before the index date except for comedications and COPD severity that were ascertained up to one year before index date The main analysis estimated the prevalence of off-label use among new users of olodaterol and indacaterol during the overall study period in each data source Data describing the medical history and comedications of the study population are presented as counts All data sources followed a common protocol and analysis plan and analysis were performed using SAS version 9.2 or higher All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards based exclusively on routinely collected data The study included 4,158 new users of olodaterol and 9,966 new users of indacaterol (Fig. 1) across the three countries. Among users of olodaterol or indacaterol, the main reason for exclusion was not being a new user. Number of users of olodaterol and indacaterol before and after fulfilling inclusion/exclusion criteria in each data source The median age ranged from 63 years (IMS RWE LPD GP panel) to 71 years (Denmark) in new users of olodaterol and ranged from 63 years (IMS RWE LPD GP panel) to 69 years (Denmark) in new users of indacaterol (Table 1) the proportion of females and males among new users of olodaterol and indacaterol was close to 50% in all data sources except in the IMS RWE LPD pulmonologist panel where 64.6% of the new users of olodaterol and 66.9% of the new users of indacaterol were males a high proportion of patients had no information recorded on lifestyle characteristics Among patients with recorded information on smoking history the proportion of those who were current smokers was around 50% in PHARMO-GP and in the IMS RWE LPD GP panel and was higher in the IMS RWE LPD pulmonologist panel which reported that 90.7% of the new users of olodaterol and 72.2% of the new users of indacaterol were current smokers There was incomplete recording of obesity in all data sources In the subset of patients in PHARMO-GP for whom information on obesity was available (72.8% of those new users of olodaterol and 64.6% among new users of indacaterol) the proportion of overweight or obese patients was 66.1% among new users of olodaterol and was 66.7% among new users of indacaterol The proportion of patients with a recorded diagnosis of alcohol-related disorders was below 10% in all health care databases for both olodaterol and indacaterol new users In general, prescriptions/dispensings for respiratory and nonrespiratory medications in the year before the index date were more frequent among new users of olodaterol than among new users of indacaterol in all data sources (Table 2) The most frequent prescription/dispensing for respiratory medications in the year before the index date among new users of olodaterol and indacaterol was LAMA The most frequent prescriptions/dispensings for nonrespiratory medications among new users of olodaterol and indacaterol were Severity of COPD among new users of olodaterol and indacaterol aged 40 years or older with COPD in PHARMO overall, PHARMO-GP, and in Denmark is presented in Table 3 The proportion of patients aged 40 years or older with severe or very severe COPD was lowest in PHARMO-GP and highest in Denmark ranging from 41.7% (PHARMO-GP) to 67.1% (Denmark) among new users of olodaterol and from 42.5% (PHARMO-GP) to 53.0% (PHARMO overall) among new users of indacaterol on-label and potential off-label use in new users of olodaterol and indacaterol the prevalence of off-label use of olodaterol and indacaterol was only somewhat higher in the IMS RWE LPD GP panel (12.4% for olodaterol and 11.9% for indacaterol) No notable differences in off-label use were observed between olodaterol and indacaterol Even in health care data sources with access to primary care data recording may be incomplete when recording is not mandatory for the GPs Incomplete recording is also supported by the fact that the proportion of patients classified as having “probable COPD” is high in all data sources but higher in data sources with no primary care data Use of olodaterol and indacaterol among patients with asthma only (and no COPD) is expected to be limited to patients who have failed to experience symptom improvement with other LABAs who may find presentation dosage or device to be less convenient or who have had drug substance-specific adverse events or contraindications Routinely collected data used in this study do not specifically record indication for use or patient preference; therefore the reported level of off-label use is at least partially attributable to the limitations of the data sources we cannot completely rule out potential misclassification of COPD as asthma although it is less likely that true asthma was misclassified as COPD it is expected that use of olodaterol and indacaterol among patients with asthma only is done with concomitant use of ICS although this was not evaluated in our study This study uses the national health care databases in the form of study results in the main manuscript and in the supplementary material can be shared and prevention of chronic obstructive pulmonary disease (Global Initiative for Chronic Obstructive Lung Disease Heads of Medicines Agency (HMA). Details: Product Name in the RMS: Striverdi Respimat, http://mri.cts-mrp.eu/Human/Product/Details/31094 (2013) Chowdhury, B. A. & Dal Pan, G. The FDA and safe use of long-acting beta-agonists in the treatment of asthma. The New England journal of medicine 362, 1169–1171, https://doi.org/10.1056/NEJMp1002074 (2010) Nelson, H. S., Weiss, S. T., Bleecker, E. R., Yancey, S. W. & Dorinsky, P. M. The Salmeterol Multicenter Asthma Research Trial: a comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol. Chest 129, 15–26, https://doi.org/10.1378/chest.129.1.15 (2006) Drug Utilisation Study for Olodaterol − 03 Aug 2016 - (Version 3.0) (2016) Pharmacy-based Medical Record Linkage Systems Kornum, J. B., Svaerke, C., Thomsen, R. W., Lange, P. & Sorensen, H. T. Chronic obstructive pulmonary disease and cancer risk: a Danish nationwide cohort study. Respiratory medicine 106, 845–852, https://doi.org/10.1016/j.rmed.2011.12.009 (2012) Schmidt, M. et al. The Danish National Patient Registry: a review of content, data quality, and research potential. Clinical epidemiology 7, 449–490, https://doi.org/10.2147/clep.s91125 (2015) Johannesdottir, S. A. et al. Existing data sources for clinical epidemiology: The Danish National Database of Reimbursed Prescriptions. Clin Epidemiol 4, 303–313, https://doi.org/10.2147/CLEP.S37587 (2012) Schmidt, M., Pedersen, L. & Sorensen, H. T. The Danish Civil Registration System as a tool in epidemiology. European journal of epidemiology 29, 541–549, https://doi.org/10.1007/s10654-014-9930-3 (2014) Jouaville, S. L., Miotti, H., Coffin, G., Sarfati, B. & Meihoc, A. Validity And Limitations Of The Longitudinal Patient Database France For Use In Pharmacoepidemiological And Pharmacoeconomics Studies. Value in Health 18, A18, https://doi.org/10.1016/j.jval.2015.03.115 (2015) Marsh, S. E. et al. Proportional classifications of COPD phenotypes. Thorax 63, 761–767, https://doi.org/10.1136/thx.2007.089193 (2008) Validation of general practitioner-diagnosed COPD in the UK General Practice Research Database Soriano, J. B., Visick, G. T., Muellerova, H., Payvandi, N. & Hansell, A. L. Patterns of comorbidities in newly diagnosed COPD and asthma in primary care. Chest 128, 2099–2107, https://doi.org/10.1378/chest.128.4.2099 (2005) Breekveldt-Postma, N. S., Koerselman, J., Erkens, J. A., Lammers, J. W. & Herings, R. M. Enhanced persistence with tiotropium compared with other respiratory drugs in COPD. Respir Med 101, 1398–1405, https://doi.org/10.1016/j.rmed.2007.01.025 (2007) Overbeek, J. A., Bakker, M. & Snoeijer, B. T. Abstract 104: The Difference Between Asthma and COPD – A Distinction Based on Dispensing Data. Pharmacoepidimeology and Drug Safety 26, 3–636, https://doi.org/10.1002/pds.4275 (2017) Verhamme, K. M. et al. Tiotropium Handihaler and the risk of cardio- or cerebrovascular events and mortality in patients with COPD. Pulmonary pharmacology & therapeutics 25, 19–26, https://doi.org/10.1016/j.pupt.2011.10.004 (2012) Study on off-label use of medicinal products in the European Union de Luise, C., Lanes, S. F., Jacobsen, J., Pedersen, L. & Sorensen, H. T. Cardiovascular and respiratory hospitalizations and mortality among users of tiotropium in Denmark. European journal of epidemiology 22, 267–272, https://doi.org/10.1007/s10654-007-9106-5 (2007) Laforest, L. et al. Frequency of comorbidities in chronic obstructive pulmonary disease, and impact on all-cause mortality: A population-based cohort study. Respiratory medicine 117, 33–39, https://doi.org/10.1016/j.rmed.2016.05.019 (2016) Schmidt, S. A. et al. The impact of exacerbation frequency on mortality following acute exacerbations of COPD: a registry-based cohort study. BMJ open 4, e006720, https://doi.org/10.1136/bmjopen-2014-006720 (2014) Perez, T., Serrier, P., Pribil, C. & Mahdad, A. COPD and quality of life: impact of the disease in primary care in France. Revue des maladies respiratoires 30, 22–32, https://doi.org/10.1016/j.rmr.2012.08.005 (2013) Covvey, J. R. et al. A comparison of medication adherence/persistence for asthma and chronic obstructive pulmonary disease in the United Kingdom. International journal of clinical practice 68, 1200–1208, https://doi.org/10.1111/ijcp.12451 (2014) Ingebrigtsen, T. S. et al. Medically treated exacerbations in COPD by GOLD 1-4: A valid, robust, and seemingly low-biased definition. Respiratory medicine 109, 1562–1568, https://doi.org/10.1016/j.rmed.2015.10.015 (2015) Pottegard, A. et al. Primary non-adherence in general practice: a Danish register study. European journal of clinical pharmacology 70, 757–763, https://doi.org/10.1007/s00228-014-1677-y (2014) Hansen, J. G. et al. The Prevalence of chronic obstructive pulmonary disease among Danes aged 45-84 years: population-based study. Copd 5, 347–352, https://doi.org/10.1080/15412550802522635 (2008) Download references Joan Forns for medical writing support and Whitney Krueger The authors would also like to thank Patricia Tennis for her contribution t o the study design and Fernie Penning-van Beest for quality control during the study in PHARMO as well as all the health care providers contributing information to the PHARMO Database Network Lisbeth Munksgård Baggesen and Dora Farkas for data analyses of the Danish National Registers Geoffray Bizouard for data analyses of IMS RWE LPD database This study was funded by Boehringer Ingelheim GmbH under a contract granting independent publication rights to the research team Boehringer Ingelheim co-authors of this manuscript provided feedback and contributed to the design of the study The sponsor had the opportunity to review the report and contribute to the dissemination of the results PHARMO Institute for Drug Outcomes Research provided substantial contributions to study design and interpretation of the data and wrote or critically reviewed the work for important intellectual content provided substantial contributions to study designed and interpretation of the data and critically reviewed the work for important intellectual content All authors approved the final version of the manuscript and are accountable for all aspects of this research and Alicia Gilsenan are employees of RTI Health Solutions a non-profit organization that conducts work for government including pharmaceutical companies like Boehringer Ingelheim Eline Houben and Jetty Overbeek are employees of the PHARMO Institute for Drug Outcomes Research This independent research institute performs financially supported studies for government and related health care authorities and several pharmaceutical companies an independent research institute that performs financially supported studies for health care authorities and several pharmaceutical companies Vera Ehrenstein and Kristina Laugesen are salaried employees of Aarhus University/Aarhus University Hospital Jukka Montonen and Laura Wallace are employees of Boehringer Ingelheim Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Download citation DOI: https://doi.org/10.1038/s41598-019-57397-5 Anyone you share the following link with will be able to read this content: a shareable link is not currently available for this article Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology Enriquetto is the new trattoria in Barcelona that celebrates classic Italian pastas Located in the Sarrià-Sant Gervasi neighborhood this restaurant is the brainchild of entrepreneurs Kim Díaz Enriquetto is located in the same place formerly occupied by Albert Cambra’s restaurant Pervers The name Enriquetto is a tribute to Enric Rebordosa Kim Díaz and Miquel Puchol decided to name the restaurant after their friend and business partner Enriquetto is a declaration of love for Italian cuisine offering simple and delicious dishes in a cozy and unpretentious atmosphere The objective is to create a place where diners feel comfortable without the bill being excessive Enric Rebordosa has personally decorated the restaurant using beautiful porcelain dishes from Limoges and La Cartuja for the dishes The attention to detail and the taste for aesthetics are reflected in every corner of the premises The trattoria has a terrace in a small square next to the restaurant which promises to be an essential meeting point in the neighborhood the partners have opened a small bar across the street Enriquetto’s menu features some of the members’ favorite pasta classics carpaccio inspired by the famous Harry’s Bar Although they do not currently make the pasta by hand The restaurant offers pasta dishes such as ravioli with burrata and red pesto sauce fettuccine Alfredo that the head waiter mixes in front of the diner thanks to a team of professionals over 50 years of age specially selected to vindicate the experience and trajectory of these workers already successfully implemented at Bar Mut allows us to offer a warm and professional service Enriquetto joins the Italian haute cuisine offer in Barcelona competing with other renowned restaurants such as Xemei The trattoria seeks to stand out for its focus on classic pasta and its cozy atmosphere without neglecting quality and authenticity in each dish If you want to delight yourself with the best classic pasta just go to Hercegovina street in the neighborhood of Sarrià-Sant Gervasi Stock images by Depositphotos La venta de la nuda propiedad Copyright © 2022 Salirporbarcelona , All rights Reserved. Created by JEZZ Media Get Recruited Faster with a Player Profile on SoccerWire.com Under-16 Girls’ National Team will travel to Portugal to participate in the UEFA Women’s International Development Tournament being held from May 12-16 in northern Portugal the USA will face Belgium on May 12 at Rebordosa AC Stadium in Rebordosa take on host Portugal on May 14 in Capital Móvel Stadium in Paços Ferreira and finish against Switzerland on May 16 at Municipal Stadium Coutada in Arcos Valdevez The USA will bring a different roster of players from the U-16 GNT squad that recently won the Torneo delle Nazioni in Italy and Slovenia That roster consisted of 10 players born in 2002 five players born in 2003 and five players born in 2001 The roster headed to Portugal is slightly younger and has 10 players born in 2002 and 10 in 2003 +READ: Girls Development Academy East Conference Recap | April 28-29, 2018 The development tournament will feature some unique rules All the matches in the tournament will consist of 40-minute halves and if the score is tied at the end of regulation teams will go directly to penalty kicks to decide the winner with three points awarded for a win in regulation two points awarded for a win in penalty kicks and one point for a loss in penalties Each team is allowed nine substitutes during a match but no more than three stoppages per team to make subs are allowed during the second half the tournament will utilize an experimental “Sin Bin” system for players that commit “temporary dismissal offences.” Red and yellow cards are issued in accordance with the Laws of the Game The temporary dismissal is only to be used when the referee would have issued a yellow card for any of the following offences: A player who has been temporarily dismissed is allowed to return to her team’s technical area and cannot be substituted for an eight-minute temporary dismissal period A goalkeeper is treated in the same way as field players A player who commits a second temporary dismissal offence in the match will receive a second eight-minute temporary dismissal and must be substituted and can not play again in the match +READ: U.S. U-16 Girls National Team wins Torneo delle Nazioni title Temporary dismissals and ‘other’ yellow cards are not combined if a player who has been temporarily dismissed returns to the field and then receives a yellow card a player who has received a yellow card and then commits a temporary dismissal offence is not sent off To underline the development nature of the tournaments each player must play at least 80 minutes across the three matches and UEFA recommends that each player should play no more than 120 minutes over two consecutive games GOALKEEPERS (2): Mia Justus (PDA; North Brunswick Neeku Purcell (Seattle Reign Academy; Seattle DEFENDERS (6): Abby Allen (Lonestar SC; Austin Andrea Kitahata (San Jose Earthquakes; Hillsborough MIDFIELDERS (6): Zoe Burns (Crossfire Premier; Issaquah Devin Lynch (Eclipse Select SC; Naperville Jillian Martinez (Lonestar SC; San Antonio FORWARDS (6): Abigail Borchers (San Jose Earthquakes; Fresno Simone Jackson (LAFC Slammers; Redondo Beach Amelia White (Fort Wayne United; Fort Wayne Join the SoccerWire College Soccer Recruiting Search Engine and learn how to be seen OVER 1 MILLION TIMES PER YEAR This site uses cookies to give you the best possible experience but do not collect personal information By continuing to use the site you agree that we can save cookies on your device The Spanish Pediatric Association (Asociación Española de Pediatría AEP) has as one of its main objectives the dissemination of rigorous and up-to-date scientific information on the various areas of pediatrics Annals of Pediatrics is an open access journal that serves as the Association's Scientific Expression Organ and constitutes the vehicle through which members communicate as well as review articles prepared by experts in each specialty and guidelines or positioning documents prepared by the different Societies/Specialized Sections integrated into the Spanish Pediatric Association a reference for Spanish-speaking pediatrics is indexed in the most important international databases: Index Medicus/Medline IBECS The aim of this study is to evaluate the effectiveness of a disaster preparedness training programme in a Paediatric Emergency Department (PED). A quasi-experimental study was conducted using an anonymous questionnaire that was distributed to health care providers of a PED in a tertiary paediatric hospital. The questions concerned the disaster plan (DP), including theoretical and practical aspects. Questionnaires were distributed and completed in January 2014 (period 1) and November 2014 (period 2). The disaster training programme includes theoretical and practical sessions. The training programme improved some knowledge about the disaster plan, but it has not improved responses in practical situations, which may be due to the low attendance at practical sessions and the time between the training programme and the questionnaires. Analizar la eficacia de un programa formativo sobre catástrofes en un Servicio de Urgencias Pediátricas (SUP). Estudio cuasiexperimental mediante encuestas dirigidas al personal sanitario del SUP de un hospital pediátrico de tercer nivel. Se evalúan aspectos teóricos y prácticos del plan de catástrofes (PC). Las encuestas son cumplimentadas en 2 periodos (periodo 1, enero del 2014, y periodo 2, noviembre del 2014), entre los cuales se realiza una formación con sesiones teóricas y situaciones clínicas. La aplicación de una formación sobre catástrofes ha mejorado algunos conocimientos del personal, pero no ha mejorado las respuestas en las situaciones clínicas planteadas, posiblemente influenciado por la baja asistencia a las sesiones prácticas y el tiempo transcurrido entre la formación y la encuesta. A disaster is any situation or event that overwhelms local response resources, and usually produces severe damage, destruction and human suffering.1–3 The impact of disasters is particularly severe in the field of paediatric emergency medicine, as children are more vulnerable and at greater risk of experiencing dehydration, infection and multiple trauma.1,4 it is essential that paediatric emergency departments (PEDs) and their personnel be properly prepared to manage these situations can result in substantial morbidity and mortality in the population Such preparedness involves a broad range of elements: availability of materials Several studies, most of them conducted outside of Spain, warn of a lack of disaster preparedness.4,6,8,9 In Spain, many PEDs do have disaster plans in place, but they are usually not up to date and are not generally known by the staff.10 The aim of this study was to analyse the efficacy of a disaster preparedness training programme in a PED We conducted a quasi-experimental pre-post intervention study by means of a survey of health care workers in which the training programme was the intervention The study took place in a tertiary paediatric hospital that receives approximately 100,000 visits a year and is the reference hospital for patients with multiple trauma The hospital has a disaster plan (DP) that was updated in 2013 and the PED is equipped with a disaster kit to be opened by the staff in case the DP is activated The target population of our study was the collective of health care workers that regularly staffs the PED (125 individuals) including nursing staff (nurse assistants and registered nurses [RNs]) and doctors in the specialties of paediatric emergency medicine We conducted the study over two time periods (period 1 in November 2014) and the training programme took place between the two (April 2014) the researchers asked the health care staff to fill out the paper-based questionnaire anonymously and no reward was offered for participating The training programme consisted of one theoretical session that explained the hospital's DP and two three-hour-long practical sessions in which various disaster-related clinical scenarios were discussed in small groups to put the DP into practice (victim triage The questionnaire was written in Spanish and based on the published literature,11 and comprised 20 multiple-answer questions (Appendix 1) It included:–Demographic data of the health care worker (sex Five theoretical questions about the external disaster plan Ten practical questions that presented clinical situations in disaster scenarios requiring the application of the DP and that assessed aspects such as victim triage Two personal questions that asked about the perceived importance of the training and whether the respondent felt prepared to respond to a disaster To score the answers for the ten practical questions each correct answer was graded with one point and each incorrect answer with zero points which were added up to obtain the total score for practical knowledge (minimum score We collected 110 questionnaires in period 1 (88% response rate) and 80 in period 2 (64% response rate). Table 1 shows the demographic data of the respondents Sixty percent of the staff that filled out the questionnaire in period 1 had never undergone disaster training of any kind Eighty percent of respondents in period 2 had completed the questionnaire in period 1 71.3% had attended the theoretical session and 43.8% had participated in the practical sessions Thirty percent of respondents in period 2 had completed the full training we observed significant differences in the awareness of the existence of a DP (77.1% vs and knowing where to find the DP (52.77% vs we also observed a significant increase in the number of staff that were aware of its existence (53.6% vs 72.5%; P=.008) and that knew where to find it in the PED (33.6% vs When it came to the responsibilities of the shift manager 33.6% of the health care workers knew them in period 1 We did not observe a significant improvement in the mean score obtained in the practical questions from period 1 to period 2 (5.8/10 vs We also did not find a statistically significant difference between the answers given in each period for any of the 10 practical questions when we analysed each of them separately The staff felt better prepared to face a disaster after participating in the training programme (15.5% vs 41.8%; P<.001) and 98.8% stated that training on this subject is important the training programme succeeded in improving certain knowledge areas in the staff mostly concerning theoretical aspects of the DP the application of this theoretical knowledge to the proposed clinical scenarios did not improve so the results we obtained were not entirely satisfactory the time elapsed between training and the survey was six months so participants may have forgotten some of what they had learned; on the other hand less than half of the staff attended the practical sessions and those that did not were unable to put the DP into practice; last of all the training programme did not include simulation exercises such as drills in the PED or virtual simulations In addition to the limitations inherent in any survey-based study our assessment of the outcomes of the training programme may be biased for lack of a control group consisting of individuals with no training We also were unable to compare the performance of the staff that participated in the training programme with that of staff that did not participate as the surveys were filled out anonymously so its results must be interpreted with caution the high dropout rate between the two periods may be a significant source of bias as the interest in disaster training of respondents in period 2 is probably greater the implementation of a specific training programme on disaster preparedness improved some of the knowledge of health care workers but was not associated with an improvement in answers given to hypothetical clinical situations they were presented with and giving incentives for staff participation The authors have no conflict of interests to declare Please cite this article as: Parra Cotanda C, Rebordosa Martínez M, Trenchs Sainz de la Maza V, Luaces Cubells C. Impacto de un programa de formación de catástrofes en el personal sanitario. An Pediatr (Barc). 2016;85:149–154. Previous presentations: This study was presented as an oral communication at the XX Reunión Anual de la Sociedad Española de Urgencias de Pediatría; April 16–18, 2015; Bilbao, Spain. It has not been published before and it is not under consideration by any other editorial board. Anales de Pediatría (English Edition) follows the Recommendations for the Conduct Editing and Publication of Scholarly Work in Medical Journals Look out for your first newsletter in your inbox soon We help you navigate a myriad of possibilities Sign up for our newsletter for the best of the city By entering your email address you agree to our Terms of Use and Privacy Policy and consent to receive emails from Time Out about news Sign up for our email to enjoy your city without spending a thing (as well as some options when you’re feeling flush) Our newsletter hand-delivers the best bits to your inbox Sign up to unlock our digital magazines and also receive the latest news By entering your email address you agree to our Terms of Use and Privacy Policy and consent to receive emails from Time Out about news, events, offers and partner promotions. Barcelona the guy had the nerve to steal the iconic modernista Muy Buenas sign the glass room divider and the entire stretch of the bar The City Council managed to get everything back and it all ended up in pieces on the ground for a year Rebordosa recalls that a craftsman they worked with at La Confitería told them that Muy Buenas was in trouble and they should go have a look to see what they could do Three years later – half of which the space was closed down and the other half under construction – Muy Buenas reopened Rebordosa says they decided that the screen represented such extraordinary artwork that the rest of the space had to be done in the same way Some people complain it's no longer authentic ramshackle wood and Cuban and later Palestinian cuisine (both dubious) What was all that doing in a bar with modernista decor with Aurelia Teichoa (Disfrutar) and Daniel Martínez (Raúl Resino) in the kitchen the goal is to find a balance between good, home-made cuisine and comfortable surrounds Some dishes are perfect for sopping up with bread and I do just that with the meatballs with cuttlefish The flavour of the sea in the sauce combined with the spiciness is intense in just the right way I keep dipping in the juice from the omelette with green beans which is finished off in the oven and with broth And I even get to top my bread with the salad of curly endive and 'flaonas' (a kind of cream empanada from Figueres) they offer a dish of the day for €13 (Mon Go for the modern Catalan cuisine that will satisfy your taste buds As for their bars at the entrance and upstairs they use only Catalan liquors in their dedicated cocktails If you can’t decide on which drink to try consider the Queen Joan Capri – a gin cocktail infused with cucumber Thanks for subscribing! 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