The only thing that could keep Luke Bellino and Sam Meriweather off the Brighton track and field record board is the schedule Both seniors came within a whisker of setting school records Friday in the Saline Golden Triangle Invitational Meriweather took second place in long jump with a leap of 21 feet He was one-half inch shy of tying the school record set by Noah Grimm in 2018 Bellino finished second in the 400-meter run in 48.98 seconds Brighton’s fastest time since Brian Cermak ran a school-record 48.9 to win the 2004 regional at Milford Bellino and Meriweather will likely have only three more opportunities to produce the little extra effort needed to break those school records the regional meet May 16 at Mason and the state Division 1 finals May 31 at East Kentwood Meriweather was also fourth in the 200 in 22.68 ran with Bellino on the fourth-place 800 relay team and was on the fifth-place 400 relay team Bellino was on a fifth-place 1,600 relay team Pinckney’s Sam Burrts was third in the 110 high hurdles in 15.40 and seventh in the 300 hurdles in 41.44 Producing fast times in the Mike Smith Elite fields were Brighton’s Tyler Brock MOVING ON: See where 27 Howell High School seniors will compete at next level ATHLETE OF THE WEEK: Pinckney's Mackenzie Burns could exceed already impressive softball numbers NATIONAL CHAMPS: Michigan national championship gymnasts from Fowlerville, Howell bonded as youngsters In the girls meet, junior Juliet Lewis became the third-fastest 800 runner in Brighton history, taking first place in 2:15.48. She is less than a second off Maddie Brown’s school mark of 2:14.59 set in the 2019 state finals Lewis also ran on the winning 3,200 relay team with Selena White Ella Lorenz and Lydia LaMarra (9:26.53) and the winning 1,600 relay team with White Payne won the 400 in 58.57 and was fifth in the 200 in 26.95 Ella Lorenz broke the Brighton freshman record in the 1,600 Lauren Parrell set the previous mark of 5:19.0 in 2015 Pinckney’s Madison Cooke was second in the 200 in 26.13 and sixth in the 100 in 12.90 Taking second for Pinckney were Mya Karolak in high jump (5-2) and Nadia Jacobs in pole vault (9-6) Brighton’s Kaydence Hoolsema was fourth in high jump at 5-0 Davea Crowe of Pinckney took fourth in the 300 hurdles in 47.75 Bissett was seventh in 11:19.17 and LaMarra eighth in 11:20.42 for Brighton Freshman Jamo Parsell won the 110 hurdles in 16.65 was on the winning 800 relay team and was third in the 300 hurdles in 43.68 to lead Brighton to a first-place finish out of nine teams Sawyer Switalski and Jaeden Byrd were also on the winning 800 relay (1:36.18) Mason Gay was second in the 100 (11.55) and 200 (23.24) while taking third in the high jump (5-8) and long jump (17-3.5) for Brighton Switalski was second in the 300 hurdles in 43.65 and third in the 110 hurdles in 17.62 Owen Collin was second in the 1,600 in 4:56.17 for the Bulldogs Pinckney’s Cole McCraw won the 3,200 in 9:49.91 Crowe won the 300 hurdles in 48.48 and took second in the 100 hurdles in 17.17 while running on the first-place 800 relay team and second-place 400 relay team Also on the winning 800 relay were Emily Clark Pinckney’s Jaelyn Ray won the 1,600 in 5:16.13 and was on the winning 3,200 relay with Aleena Bower Hoolsema won high jump at 5-3 and Natalie Mazur was second in the 400 in 1:06.87 for Brighton Alexis Erickson was second in discus (86-4) and Emily Clark second in pole vault (8-0) for Pinckney Junior Elliana Neuer became the second-fastest 1,600 runner in Hartland history who set the school record of 4:54.6 in 2010 Neuer also ran 2:20.68 in the 800 to finish 10th and was on the second-place 3,200 relay team that ran 9:45.00 with Hannah DePestel Sophomore Kendel Simmons moved into third on Hartland’s all-time pole vault list Howell’s Rori Gregory was fourth in high jump at 5-0 Earning second-place finishes for Howell were Jack MacGregor in the 3,200 (9:26.18) and Romen Williams in high jump (6-2) Hartland’s Roman Ignagni was fourth in shot put at 49-10 Fowlerville junior Landon Aeschliman cleared a personal-best 12-6 to finish second in pole vault Kody Sweet was fourth in long jump at 19-10.25 Logan Santana struck out six batters in three shutout innings and drove in two runs Josh Soneral drove in five runs in the doubleheader and Daniel Hampton was 3-for-3 in the second game for Howell Justin Jones (four innings) and Blake Lower (three) combined for a two-hit shutout in the first game Mickey Brown struck out 11 batters and allowed one hit in six innings while Aspen Jendrusik was 3-for-3 with two RBIs in the first game for Stockwell Teddy Gottbreht was 4-for-5 with two doubles and four RBIs and Drew Goodwin had two doubles for the Sentinels (11-2-1) went 2-for-2 and drove in two runs for Fowlerville Zoey Overton hit two home runs and drove in four runs in Howell’s final game The Highlanders lost 4-3 to Utica Ford and 11-1 to Frankenmuth in their first two games Easton Lavery and Lara Anderson homered for Howell against Ford Alli Ulanowski pitched 5 2/3 innings of no-hit shutout relief against Dexter Fowlerville lost 9-3 to Portland in its first game before beating Saranac 13-7 and Haslett 12-2 Kiely Davis was 4-for-4 with three RBIs against Saranac and McKenna Maybee was 3-for-3 with two RBIs against Haslett Tommi Kleinschmidt was 6-for-8 with two RBIs in the Gladiators’ two victories Howell’s Cody Baker maintained his torrid scoring pace with eight goals and one assist He’s scored at least eight goals in the Highlanders’ last three victories Caleb Edwards had three goals and two assists Joe Skoczylas had seven goals and Cass Whitaker made 16 saves for Brighton (10-2) Ella Toth and Mia Balogh scored for Brighton Eligible for a Nurse Assist Recall lawsuit Suboxone Tooth Decay Depo-Provera Ozempic Wegovy and Mounjaro Bard PowerPort Yes. Sterile saline recall lawsuits are being investigated after Nurse Assist recalled certain prefilled syringes as well as bottles of 0.9% Sodium Chloride Irrigation and Sterile Water due to potential bacterial contamination that could lead to severe infections among users Financial compensation may be available through a Nurse Assist recall lawsuit for individuals who used the recalled sterile water or saline solutions and experienced any of the following injuries: Nurse Assist produces both saline solutions and sterile water products spray cans or medical kits under various different brands that are widely used by medical providers throughout the U.S. However it was discovered that the sterile solutions may be contaminated with harmful bacteria which could cause severe or life-threatening infections. The saline solutions blend precise amounts of sodium chloride with purified water, which is designed for rinsing and cleansing medical devices The sterile water products are free from any added salts and are intended for medical uses that require salt-free solutions In November 2023, a Nurse Assist saline and sterile water solutions recall was issued after it was discovered that a packaging seal defect could compromise the sterile barrier and allow bacteria to enter the products. This created a serious infection risk for patients throughout the U.S. particularly if they have compromised immune systems Nurse Assist recall lawsuits are now being investigated by lawyers nationwide alleging that Nurse Assist LLC neglected their duty to provide safe sterile medical products and failed to adequately warn consumers and healthcare providers about the risks associated with the contaminated products Lawyers provide free consultations and claim evaluations to help families determine if financial compensation may be available through a Nurse assist recall lawsuit settlements for individuals who used the sterile cleaning solutions and developed any of the following side effects Nurse assist recall lawsuits are being filed for individuals who developed infections or other injuries caused by contaminated saline solutions and sterile water products May 1, 2025 Update: A new lawsuit has been filed against Nurse Assist and McKesson by a Tennessee woman who developed a severe Vibrio vulnificus infection after repeatedly using recalled saline solution to clean lymphedema wounds was contaminated and led to emergency medical treatment and lasting complications As additional reports of infections surface the number of lawsuits tied to the Nurse Assist sterile saline and water recall is expected to grow in the coming months 2025 Update: Lawyers are continuing to investigate claims related to the sterile water and sodium chloride recalls as more individuals begin to connect these products to their infections Hospitals have recently started sending letters to patients treated with the recalled solutions many affected individuals are just now discovering the link between the recalled products and their injuries 2024 Update: One of the first Nurse Assist recall lawsuits was filed on November 5 alleging that contaminated sodium chloride saline solution caused a 26 year old man to develop a severe infection which sent him into septic shock and cardiac arrest April 15, 2024 Update: The FDA issued a Safety Communication today announcing a Nurse Assist sterile water and saline solution recall expansion which now includes additional medical products and manufacturers of kits and trays that contain potentially contaminated Nurse Assist recalled products November 6, 2023 Update: The U.S. Food and Drug Administration (FDA) announced the Nurse Assist sterile water and saline recall on November 6 indicating the manufacturer found the packaging seal may potentially break and compromise the sterile barrier which can introduce harmful bacteria into the solution The U.S. Food and Drug Administration (FDA) first announced the Nurse Assist recall on November 6 impacting numerous water-based medical products including various sizes of 0.9% Sodium Chloride Irrigation USP and Sterile Water for Irrigation USP According to the manufacturers voluntary recall notice the water-based medical products may not be sterile and could potentially be contaminated with bacteria that could cause serious or life-threatening infections Officials warned that the products were distributed individually and possibly in repackaged medical convenience kits throughout the United States and Canada Although the FDA indicates at that time that there had been no reports of patient harm reported healthcare professionals and individuals were instructed to immediately check their inventory and stop using the affected products a number of reports are now beginning to emerge involving severe and sometimes fatal infections caused by the contaminated sterile solutions While the initial recall warned that Nurse Assist sterile saline and water products may have been repackaged in medical kits details about which specific products were impacted was not confirmed at the time However, a Nurse Assist recall expansion was announced in April 2024 in direct response to a number of adverse events emerging from the use of impacted saline or sterile water products repacked in medical kits and trays The following brands of saline and sterile water medical products have been recalled over bacterial contamination risks: Exposure to bacteria in contaminated Nurse Assist saline and water solutions can lead to a range of serious and potentially life-threatening infections and side effects Did you suffer injuries while Using Nurse Assist sterile products Share your story with AboutLawsuits.com and have your comments reviewed by a lawyer to determine if you may be eligible for a lawsuit To prove exposure to recalled saline or sterile water solutions distributed through hospitals lawyers can obtain medical records showing usage during treatments request purchase histories from pharmacies If you received saline or water-based solutions during a hospital stay these may have been administered directly by medical staff To determine if you were exposed to a recalled solution which should include detailed information about the medications and solutions administered during your treatment You can request these records from the hospital’s medical records department contacting the hospital directly and asking if they used any recalled products in their procedures or supplies may provide a quicker answer For those who were prescribed a saline or water solution to use at home after hospital discharge verifying exposure may involve checking discharge instructions or home-care kits provided by the hospital These records often include a list of supplies and medications given to the patient reach out to the hospital’s pharmacy or patient support services as they can confirm if any recalled solutions were dispensed for home use and whether you may have been exposed If you purchased saline or water-based solutions directly from retailers you can check your purchase history for relevant product details This information can help determine if the product you bought was part of the recall if you received any direct notifications from the retailer about a recall it’s essential to review these notices for specific exposure risks contacting the retailer or the manufacturer can provide clarification on whether your purchased product was included in the recalled batches a lawyer can assist you in gathering hospital records and receipts to establish proof of exposure to the recalled solutions Babak Sohrabian and Mojgan Homaie filed a SteriCare wrongful death lawsuit on behalf of their deceased son in California Superior Court on November 5 The defendants named in the lawsuit include Nurse Assist Kameron Sohrabian was prescribed four bottles of Nurse Assist 0.9% sodium chloride saline solution to clean open wounds on his legs caused by lymphedema Kameron experienced severe pain and abnormal swelling which was later diagnosed as a bacterial infection caused by the contaminated saline solution where he went into septic shock and suffered cardiac arrest The lawsuit claims that the defendants failed to warn of the bacterial contamination in the saline solution His parents allege that timely notification of the contamination could have prevented his exposure and tragic outcome The family now seeks compensation for medical costs and the profound emotional and personal loss experienced due to Kameron’s untimely death Nurse Assist recall lawyers provide free consultations and claim evaluations for individuals who have suffered injuries caused by the contaminated saline and sterile water products To determine whether you or a loved one may be eligible for a Nurse Assist recall lawsuit submit information about your potential claim for review by a personal injury lawyer to determine whether a settlement or lawsuit payout may be available There are no fees or expenses unless a recovery is obtained in your case If you or a loved one developed an infection or other injuries from contaminated saline or sterile water products submit information for review by a lawyer to determine if you may be eligible for a Nurse Assist recall lawsuit settlement NOTE: Providing information for review by an attorney does not form an attorney-client relationship Δdocument.getElementById( "ak_js_1" ).setAttribute( "value" Privacy Policy Terms Of Use and Disclaimers RSS Site Sponsored By: Saiontz & Kirk, P.A Δdocument.getElementById( "ak_js_2" ).setAttribute( "value" Δdocument.getElementById( "ak_js_3" ).setAttribute( "value" The Illinois Department of Natural Resources’ long-awaited off-highway vehicle park in southern Illinois will officially open to riders on Friday Sahara Woods State Recreation Area near Carrier Mills in Saline County features Illinois’ first state-managed off-highway vehicle (OHV) trail system in Illinois The nearly 30 miles of two-way trails are designed to meet a growing demand for motorized recreation The Sahara Woods trails were funded in part by federal grants and IDNR capital funds The land at Sahara Woods was the site of an active coal mine from 1936 to 1995 The strip-mined terrain was donated to IDNR in 1999 and the department transformed the site through reclamation efforts to address environmental and safety concerns Riders can visit Sahara Woods online for permit and registration details Sahara Woods State Recreation Area is 5 miles west of Harrisburg contact the OHV trails office at 618-707-1411 or email dnr.saharawoodsohv@illinois.gov Metrics details Salt pillow growth leads to the deformation of the suprasalt strata and can affect geological carbon storage in saline aquifers A concern for storage sites on land is the drinking water because the impact of the deformation on fluid pathways and groundwater systems needs to be studied we present new seismic data from a potential carbon storage site in Denmark A high-resolution seismic dataset was acquired using a strategically deployed nodal array and a landstreamer to assess the effects of the Permian Zechstein salt migration on the layers above a salt pillow We create a geological model of the subsurface through correlation of reflection data with borehole data and investigate the main Upper Triassic Gassum Formation reservoir Our findings reveal a fault system linked to salt diapirism and evidence of salt pillow growth from the Triassic into the Miocene We image up to 2 km-wide Quaternary palaeovalleys which incise the deformed overburden and serve as key groundwater aquifers These results have implications for fluid transport in deep saline aquifers above the salt pillow and for clarifying the deformation impact on the shallower groundwater systems salt pillows have concordant contact with the overlying strata This is significant for the capacity and connectivity of saline aquifers in the overburden detailed investigations are limited due to restricted access or insufficient resolution of subsurface geophysical data These new seismic surveys showcase a unique opportunity of applying environmentally friendly and imaging strategies onshore while collecting high-quality open-access data in urban environments Here, we focus for the first time on the seismic survey at the Thorning salt pillow site (Fig. 1) We present the results of the combined deep and shallow high-resolution seismic acquisition solution to simultaneously image the salt pillow and suprasalt strata including the overlying shallower groundwater systems The unique feature of the study area is the abundance of Quaternary palaeovalleys which can provide insight into the interrelation between the palaeovalleys and deformed overburden The new results are critical not only for investigating the Upper Triassic Gassum Formation for $\hbox {CO}_2$ storage and mapping groundwater resources but also help to recognise the importance of detecting faults between the candidate $\hbox {CO}_{2}$ reservoir and drinking water aquifers A potentially porous interval of the Frederikshavn Formation is only half the thickness of the sandstone of the Gassum Formation based on the data from the Nøvling 1 well The overlaying seal consists of the Jurassic–Lower Cretaceous mudstone below R11 well data suggest the presence of additional formations which may contain porous rocks at depths of 2–4 km below the Oddesund Formation that need further petrological analysis The cross-cutting relationships between the N–S oriented channels and roughly E–W geometries indicates the presence of multiple generations of valley formation the lower-lying terrain along the edge of the deformed suprasalt strata may have guided the course of the channels These observations suggest that the salt pillow and the southern salt diapir may have formed a more singular structure during the early stages of their evolution This relationship may have been influenced by the location of the salt diapir due to the presence of an ice-sheet margin in the study area explains the dense distribution of the palaeovalleys in the area Drinking water aquifers may be present in the palaeovalleys and the identified discontinuous and cross-cutting internal features of the valley infills suggest repeated episodes of erosion and subsequent deposition Considering that the palaeovalley incisions extend down into the Chalk Group the hydrogeological network is likely interconnected with different aquifer systems palaeovalley mapping is critical for groundwater aquifer exploration and enhances our knowledge of groundwater vulnerability to GCS activities in regions affected by salt tectonics Salt tectonics can significantly affect the saline aquifers targeted for carbon storage and the groundwater systems above Using a dual-element seismic acquisition system comprising landstreamer and nodal recorders we were able to image geological features at different depths with high-resolution The new data reveal Quaternary palaeovalleys and faults that truncate the reservoirs and seals which are associated with the salt pillow growth and diapirism some of the faults appear continuous up to the base of the palaeovalleys These findings form the basis for modelling the reservoir structure and fluid pathways which is important for assessing the long-term safety and integrity of the carbon storage site Two synchronized 12 tonne seismic sources were used for the seismic lines P1–P5 which were later replaced by a single 18 tonne source for the seismic lines P6–P8 The 18 tonne source was first tested and calibrated in the field to deliver an equivalent force to the two 12 tonne sources ensuring that both setups are directly comparable Three sweeps were generated every 10 m at the receiver location for a better signal-to-noise ratio A linear 18 s long sweep with a 10–140 Hz bandwidth was chosen based on previous GCS surveys in Denmark during the scope of the same project The shots were accurately time-stamped using a global positioning system (GPS) and simultaneously recorded by the nodal array and landstreamer Fixed or asymmetric split-spread roll-along geometry of approximately 600–1200 live recorders with 10 m spacing was used for the array depending on the length of the profile The position of the nodal recorders was measured using a differential global positioning system (DGPS) The landstreamer was towed by the rear seismic source along the side of the road adjacent to the nodal array the landstreamer consists of 1 to 5 segments each containing 20 three-component (3C) MEMS with 2 m spacing By using a combined nodal and landstreamer seismic acquisition setup were imaged with high-resolution using two complementary datasets The nodal dataset offers good overall reflectivity but may require significant resources particularly in areas with complex geological structures and thin layers within unconsolidated shallow sediments the landstreamer is designed with 3C broadband MEMS system accelerometers MEMS are less susceptible to electromagnetic noise from strong power lines in urban environments due to their fully digital transmission The broadband response improves the vertical seismic resolution allowing for the imaging of thinner seismic features based on the ratio between the maximum and minimum signal frequencies The unmigrated stacked data were further filtered using a coherency filter (FX-deconvolution) Migration was performed using a finite-difference migration algorithm which is imaged only in shot gathers with minimal groundroll noise advanced noise attenuation solutions may be used for complementary deep reservoir imaging using the landstreamer dataset These sources have collocated points from which seismic features could be traced to the study area allowing for consistent geological interpretation The seismic horizons and transecting faults were picked in all seismic profiles and used to create the structural time maps The palaeovalleys were modelled using both the picked horizons and a palaeovalley map which is based on prior electromagnetic surveys Stille, H. The upthrust of the salt masses of Germany. AAPG Bull. 9, 417–441. https://doi.org/10.1306/3D9326C3-16B1-11D7-8645000102C1865D (1925) Hudec, M. R. & Jackson, M. P. A. Terra infirma: Understanding salt tectonics. Earth-Sci. Rev. 82, 1–28. https://doi.org/10.1016/j.earscirev.2007.01.001 (2007) Salt Tectonics: Principles and Practice (Cambridge University Press Trusheim, F. Mechanism of salt migration in Northern Germany. AAPG Bull. 44, 1519–1540. https://doi.org/10.1306/0BDA61CA-16BD-11D7-8645000102C1865D (1960) Hjelm, L. et al. Capture, Storage and Use of CO2 (CCUS). Evaluation of the CO2 storage potential in Denmark. Vol.1: Report & Vol 2: Appendix A and B [Published as 2 separate volumes both with Series number 2020/46]. gpub https://doi.org/10.22008/gpub/34543 (2022) Hospers, J., Rathore, J. S., Jianhua, F., Finnstrøm, E. G. & Holthe, J. Salt tectonics in the Norwegian-Danish Basin. Tectonophysics 149, 35–60. https://doi.org/10.1016/0040-1951(88)90117-5 (1988) Danielsen, J. E., Auken, E., Jørgensen, F., Søndergaard, V. & Sørensen, K. I. The application of the transient electromagnetic method in hydrogeophysical surveys. J. Appl. Geophys. 53, 181–198. https://doi.org/10.1016/j.jappgeo.2003.08.004 (2003) Jørgensen, F., Sandersen, P. B. E. & Auken, E. Imaging buried Quaternary valleys using the transient electromagnetic method. J. Appl. Geophys. 53, 199–213. https://doi.org/10.1016/j.jappgeo.2003.08.016 (2003) Jørgensen, F. & Sandersen, P. B. E. Buried and open tunnel valleys in Denmark-erosion beneath multiple ice sheets. Quat. Sci. Rev. 25, 1339–1363. https://doi.org/10.1016/j.quascirev.2005.11.006 (2006) Jørgensen, L. F. & Stockmarr, J. Groundwater monitoring in Denmark: Characteristics, perspectives and comparison with other countries. Hydrogeol. J. 17, 827–842. https://doi.org/10.1007/s10040-008-0398-7 (2009) Høyer, A. S., Jørgensen, F., Sandersen, P. B. E., Viezzoli, A. & Møller, I. 3D geological modelling of complex buried-valley network delineated from borehole and AEM data. J. Appl. Geophys. 122, 94–102. https://doi.org/10.1016/j.jappgeo.2015.09.004 (2015) Bind 1: Hovedrapport (De Nationale Geologiske Undersøgelser for Danmark og Grønland Papadopoulou, M. et al. Innovative land seismic investigations for CO2 geologic storage in Denmark. Geophysics 88, 251–266. https://doi.org/10.1190/geo2022-0693.1 (2023) Malehmir, A. et al. Fault intersections control short period intraplate start-stop seismicity in the Korean Peninsula. Tectonophysics 834, 1–11. https://doi.org/10.1016/j.tecto.2022.229387 (2022) Zappalá, S. et al. Crustal-scale fault systems in the Korean peninsula unraveled by reflection seismic data. Earth Space Sci. 9, 1–14. https://doi.org/10.1029/2022EA002464 (2022) Zappalá, S. et al. Combined onshore and offshore wide-scale seismic data acquisition and imaging for carbon capture and storage exploration in Havnsø, Denmark. Geophysics 89, 257–272. https://doi.org/10.1190/geo2023-0503.1 (2024) Malehmir, A., Markovic, M., Abramovitz, T. & Gregersen, U. Geological carbon storage site characterization using a dual element seismic recording technology. Sci. Rep. 15, 1–13. https://doi.org/10.1038/s41598-025-96012-8 (2025) Westgate, M. et al. Seismic imaging of halokinetic sequences and structures with high-resolution, dual-element acquisition, and processing: Applications to the Gassum structure in eastern Jutland, Denmark. Earth Space Sci. 1–15, 2025. https://doi.org/10.1029/2024EA004014 (2025) Vejbæk, O. V. & Britze, P. Geologisk kort over Danmark. Geological map of Denmark 1:750 000. Top præ-Zechstein (to vejs løbetid og dybde). Top pre-Zechstein (two-way traveltime and depth). DGU Kortserie 45, 1–9. https://doi.org/10.22008/FK2/F9DWMB/IMCMD5 (1994) Lithostratigraphic subdivision (Danmarks Geologiske Undersøgelse Serie A Madirazza, I. & Jacobsen, B. H. Nøvling: An unusual salt structure on the southern margin of the Danish Zechstein Basin. Bull. Geol. Soc. Denmark. 44, 139–149. https://doi.org/10.37570/bgsd-1998-44-08 (1998) Nielsen, L. H. Late Triassic–Jurassic development of the Danish Basin and the Fennoscandian Border Zone, southern Scandinavia. GEUS Bull. 1, 459–526. https://doi.org/10.34194/geusb.v1.4681 (2003) Andersen, H. L. & Surlyk, F. The Cretaceous-Palaeogene boundary at Stevns Klint, Denmark: Inversion tectonics or sea-floor topography?. J. Geol. Society 161, 343–352. https://doi.org/10.1144/0016-764903-021 (2004) Bjerager, M. & Surlyk, F. Benthic palaeoecology of Danian deep-shelf bryozoan mounds in the Danish Basin. Palaeogeogr. Palaeoclimatol. Palaeoecol. 250, 184–215. https://doi.org/10.1016/j.palaeo.2007.03.008 (2007) Bjerager, M., Surlyk, F., Andersen, H. L., Thibault, N. & Stemmerik, L. Danian cool-water coral reefs in southern Scandinavia localised over seafloor highs. Mar. Petroleum Geol. 27, 455–466. https://doi.org/10.1016/j.marpetgeo.2009.09.008 (2010) Smed, P. Die Entstehung der dänischen und norddeutschen Rinnentäler (Tunneltäler) - Glaziologische Gesichtspunkte. E &G - Quaternary Science Journal 48, 1–18. https://doi.org/10.23689/fidgeo-1398 (1998) Boldreel, L. O. On the structural development of the salt dome province in NW Jutland, Denmark, based on seismic studies. First Break 3, 1–7. https://doi.org/10.3997/1365-2397.1985015 (1985) Geil, K. The development of salt structures in Denmark and adjacent areas: the role of basin floor dip and differential pressure. First Break 9, 1–17. https://doi.org/10.3997/1365-2397.1991022 (1991) Frederiksen, S., Nielsen, S. B. & Balling, N. A numerical dynamic model for the Norwegian-Danish Basin. Tectonophysics 343, 165–183. https://doi.org/10.1016/S0040-1951(01)00223-2 (2001) Reservoir Compartmentalization (Geological Society of London Hardt, J., Dooley, T. P. & Hudec, M. R. Physical modeling of ice-sheet-induced salt movements using the example of northern Germany. Earth Surface Dynamics 12, 559–579. https://doi.org/10.5194/esurf-12-559-2024 (2024) Nielsen, M. H. Signature and timing of the Kattegat Ice Stream: Onset of the Last Glacial Maximum sequence at the southwestern margin of the Scandinavian Ice Sheet. Boreas 32, 227–241. https://doi.org/10.1111/j.1502-3885.2003.tb01439.x (2008) Pedersen, T. V., Rasmussen, E. S. & Kristensen, M. Detailed mapping of Miocene sand-rich deposits in Denmark with high-resolution 2D land streamer vibroseis. First Break 30, 45–50. https://doi.org/10.3997/1365-2397.30.8.60904 (2012) Encyclopedic Dictionary of Applied Geophysics (Society of Exploration Geophysicists Download references The seismic survey was funded by the Geological Survey of Denmark and Greenland (GEUS) as part of Denmark’s carbon capture and storage (CCS) projects 2022–2024 and was completed through a collaboration between Uppsala University and the Geological Survey of Denmark and Greenland (GEUS) for their assistance in leading the data acquisition Open access funding provided by Uppsala University Geological survey of Denmark and Greenland led the seismic data acquisition together with J.P; J.P made the figures and wrote the manuscript; A.M supervised the project and assisted with manuscript revision/improvement; M.B. contributed to the geological interpretation All authors discussed the results and reviewed the manuscript The authors declare no competing interests Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Download citation DOI: https://doi.org/10.1038/s41598-025-99721-2 Anyone you share the following link with will be able to read this content: a shareable link is not currently available for this article Sign up for the Nature Briefing newsletter — what matters in science Share on FacebookShare on X (formerly Twitter)Share on PinterestShare on LinkedInLINCOLN (KOLN) - Thunderstorms moved through eastern Nebraska late Thursday afternoon and evening Tornado Warnings were issued in Saline and Jefferson Counties briefly Douglas County including parts of Omaha experienced flash flooding. Lincoln Electric System reported nearly 2,000 people without power around 4 p.m Widespread severe weather is not expected this evening but the Severe Weather Center is tracking isolated events. Submit photos and videos here. Showers and storms are expected this evening and into the overnight hours as well Rain will then likely taper off into the morning hours Friday Another round is then possible Saturday afternoon as well Click here to subscribe to our 10/11 NOW daily digest and breaking news alerts delivered straight to your email inbox KARK Video: Attorney for Hot Spring County Sheriff Scott Finkbeiner speaks after plea deal – The former sheriff of Hot Spring County has been arrested and jailed in Saline County on Friday Inmate records show Scott Finkbeiner is being held on behalf of the FBI The FBI confirmed that the former sheriff was arrested “on a court authorized document,” which was confirmed by the U.S Attorney’s Office for the Western District of Arkansas A spokesperson for that office confirmed that Finkbeiner is scheduled to appear in court at 10 a.m and would make no further statements on the matter Finkbeiner pleaded guilty in February to falsifying concealing and misleading information in an FBI drug activity investigation count two of the six federal charges he was facing related to the FBI investigation He resigned his position as sheriff the same day and is awaiting sentencing. He had ceased all law enforcement duties as of December 2023 after federal and county charges were brought against him surrounding the FBI investigation Finkbeiner is still facing state charges in Hot Spring County of unauthorized access to criminal records for personal gain and a second charge of sexual solicitation. these are the actual most popular baby names so far in 2025 Whether it’s a short vacation or they’re jetting off to begin their career show the future traveler you care with a meaningful graduation gift National Teacher Appreciation Week begins May 5 take advantage of these freebies and deals Metrics details Impedance and voltage of monopolar currents are directly related a change in behavior of these currents are achieved in endoscopy the underlying electrophysical mechanisms of this effect remain poorly explained This investigation assessed the relationship between the electrical parameters and the surrounding environment for three high-voltage monopolar coagulation currents commonly used for therapeutic endoscopy Six consecutive applications per setting and per environment were performed with dissection knife on porcine kidney When transitioning from air to saline immersion a 99% decrease in impedance was observed for all current settings tested (AirRange: 4400–8150 Ω SalineRange: 64–71 Ω; p < 0.01 for all settings) This resulted in a 52-78% reduction in peak voltage (AirRange: 920–1165 V SalineRange: 257–499 V; p < 0.01 for all settings) and a 237-2030% increase in power delivered (AirRange: 3–19 W SalineRange: 50–117 W; p < 0.01 for all settings) The dramatic decrease in impedance results in a sharp reduction of voltage explaining the coagulation effect observed when passing from air to saline-immersion therapeutic endoscopy All electrosurgical currents are affected by the device itself and environmental conditions The basic physical principles of electricity are led by both Ohm’s law and the equation of electric power according to the relationship between impedance and voltage – i.e. Impedance = Voltage2/Power – which in turn is associated with the cutting effect of monopolar high-voltage currents the electrophysical mechanisms when passing from air to saline-immersion therapeutic endoscopy have not been explored To better understand this phenomenon and explore potential uses of this technique this study aimed to examine how electrical current behaves in two different settings: atmospheric air and saline immersion this pre-clinical research sought to uncover how these environments affect the performance and therapeutic outcomes of currents usually adopted in GI endoscopy We assessed the behaviour of three different high-voltage monopolar coagulation currents usually used in third-space endoscopy (preciseSECT both in atmospheric air and in a 0.9% saline solution were continuously recorded during the procedures These parameters are related according to the following formula: The peak voltage of the current is considered responsible for the spark creation that is associated with the cutting effect of the current was qualitatively and quantitatively evaluated We employed an ex-vivo porcine model for all experiments Kidneys were obtained from a domestic pig at a local slaughterhouse each kidney was thawed in a water bath at 25 °C for 30 min to ensure even thawing and to prevent any change on the biochemical and biomechanical properties of the material The kidneys were maintained at room temperature (22 °C) throughout the experiments To facilitate consistent application on the homogeneous renal cortex each kidney was precisely cut with a sharp knife This preparation allowed us to directly compare the effects of the two different environments under each experimental setting This study utilized the Erbe VIO®3 electrosurgical generator (REF with the settings configured to preciseSECT E6.5 and forcedCOAG E3.0 (further details in Suppl These specific settings were selected to replicate the dissection and coagulation currents typically used in therapeutic endoscopy the electrosurgical generator has been programmed to limit the power delivered according to cutoffs specific for each current (limit preciseSECT: 65 W; limit swiftCOAG 120 W; limit forcedCOAG 50 W) for safety reasons Germany) was employed in an ex-vivo laboratory setting to conduct the experiments the Erbe VIO-docu (Erbe Elektromedizin GmbH specifically designed to capture and analyze electrical data from the VIO®3 this tool works in a fashion similar to a standard oscilloscope but facilitates the real-time acquisition of a broad range of electrical data and power (W) directly from the VIO®3 device data from the VIO-docu were systematically collected across all modes and environments This graph shows the parameter variations when passing from air to saline solution with each of the three currents tested in the ex-vivo model Power (Watts) and Impedance (Ohms) are reported the coloration of the tissue specimens presented as coagulation margin around the treatment area was qualitatively evaluated by a blinded technician under magnification of an incident light microscope whereas the surrounding whitish halo reflects a lateral coagulation effect (whitish appearance indicative for protein denaturation due to the heating causes coagulation) For the purpose of quantitative assessment a blinded technician conducted a measurement of the thermal spread on each separate application area We expressed all electrical parameters as medians with interquartile range (IQR – 25th to 75th percentile) We compared the median values of electrical parameters across the different environments under identical electrical settings by employing a non-parametric Mann-Whitney test (since the sample size per mode and environment was 6) The values of the lateral thermal spread were expressed also as the median with IQR The Mann-Whitney test was also employed here to facilitate comparisons between different environments Data were compiled into an Excel spreadsheet (Microsoft Excel 2010; Microsoft Corporation Statistical analyses were conducted using Prism 9 (GraphPad Software Relationship between voltage and impedance in air and saline immersion setting the decrease in impedance results in exponential drop of voltage with each of the three currents tested in an ex-vivo animal model The internal programing of the preciseSECT mode also adopted to the demand for additional power by increasing the number of power cycles (Supp Tissue effect on porcine kidney in air/CO2 (left) and saline environment (right) Cutting was performed with a HybridKnife® I-Type (Erbe REF 20150-061) with constant speed (1 mm/s) and cutting depth (1 mm) at room temperature Whitish color: coagulation effect; Brownish color: cutting effect The relevance of our findings is related with the fact that this change of behavior appears to be a universal law of any current when transitioning from air to saline solution all the three currents tested showed a 99% drop of the impedance when moving from air to saline solution This dramatic drop in impedance resulted in a consequent decrease in peak voltage according to the relationship between voltage and impedance the drop in peak voltage explains the predominant coagulation effect as a relatively high-voltage is required for spark formation that is necessary for the cutting effect the markedly reduced cutting effect observed in saline immersion in the animal model is to be referred to the decrease in the peak voltage As internal programming of electrosurgical modes is designed to deliver a specified amount of energy to the tissue this drop in voltage is compensated by the increase in power up to the fixed safety limit in power of the mode this increased power is converted to heat and ultimately an even more pronounced coagulation effect a deeper and wider coagulation effect (whitish coloration around the application) can also be attributed to a greater dispersion of electrical charges due to the medium used (saline solution) and not only to the reduction in the total impedance of the medium through which the current is conducted When transitioning from air to saline solution two currents were associated with a 10- to 23-fold increase in power while only 2.5-fold increase was observed in the remaining current The minimal lateral extension of the thermal effect observed with PreciseSECT mode is likely due to its intelligent energy modulation system which adjusts energy delivery based on tissue impedance feedback This regulation results in localized energy deposition and minimized thermal spread two currents resulted in a ≥ 1 mm extension of the lateral thermal effect while no extension was found for the third setting This is likely to be clinically relevant as the wider thermal effect permits a complete coagulation of the whole vessel wall explaining the pre-sealing of large vessels observed in clinical practice a less lateral spreading effect could be useful to minimize deep thermal injury especially when the deep layer is too close to the knife the findings of our study may be applied to any endoscopic technique where a pronounced coagulation effect is needed we already showed the benefit of the air-saline immersion transition for coagulating large vessels in third-space endoscopy and after endoscopic mucosal resection as both prophylaxis and treatment intervention cap-assisted procedures allow for easier switching from air to saline solution within the distal attachment even when the entire procedure is not completely under saline immersion we cannot exclude beneficial application of this technique in other areas outside gastrointestinal endoscopy we cannot exclude that the exponential power increase of the current may result in adverse events in clinical practices this is likely to be prevented by the caution when trying unexplored and untested modes under saline and also by the electrosurgical algorithm that limits the maximum power delivered This is in line with our observation of no major adverse events when applying this approach in clinical practice also due to the lasting cushion of water in submucosa it also simplifies the detection of the bleeding point which is of critical importance during the creation of the submucosal tunnel the replacement of gas with saline solution avoids gas-related adverse events such as subcutaneous emphysema and tension capno-peritoneum Some limitations are present in this study we utilized fixed settings to provide a controlled comparison across the three modes in air and saline environments These settings were chosen based on their relevance in clinical practice aiming to establish a baseline understanding of their electrophysical properties We recognize that the applicability of our findings could be enhanced by exploring a broader range of settings and exploring a broader range of parameters as different clinical scenarios may require adjustments All the settings used are monopolar so that our results cannot be expanded to the bipolar currents generally used in surgery we employed ex vivo porcine kidney tissue due to its homogeneous parenchymal structure which allows for the better visualization of tissue effects and provides consistent electrical parameters (impedance The moderate conductivity of kidney tissue supports effective energy transfer during electrosurgery making it suitable for assessment of both cutting and coagulation effects the kidney cortex shares similarities with the liver another parenchymatous organ widely utilized for studying tissue-electrosurgical interactions We acknowledge that this model does not perfectly replicate the layered GI tract structure we believe it acceptably represents the higher cell-density vessel wall than the submucosal tissue the current model did not include the blood flow as well as intraprocedural bleeding that could have affected the variables we measured particularly the heat sink effect in saline could most likely reduce lateral thermal spread Our controlled setup allowed us to isolate and assess the basic electrophysical properties and to assess the corresponding tissue effect but in vivo studies would be better to validate these findings we propose that an understanding of the fundamental behavior of currents in different environments should be integrated with existing clinical observations in order to form a comprehensive understanding of the phenomenon it would be ideal to have electrosurgical setting created for saline immersion environments possibly utilizing intelligent algorithm that adapt the current for the blend coagulation and cutting effect required the transition from air to saline immersion setting modulates the voltage and power of the applied monopolar currents as a result of a profound decrease in impedance in the saline environment thereby amplifying the coagulation effect while attenuating the cutting effect This explains the desired coagulation effect previously observed in this setting The data that support the findings of this study are available from ERBE but restrictions apply to the availability of these data which were used under license for the current study Data are however available from the authors upon reasonable request and with permission of ERBE Endoscopic vessel sealing: a novel endoscopic precoagulation technique for blood vessels during endoscopic submucosal dissection Digestive endoscopy: official journal of the Japan Gastroenterological Endoscopy Society Venkat, M. & Visrodia, K. Management of Adverse Events of Submucosal Endoscopy. Gastrointest Endosc Clin N Am [Internet]. Jan 1 [cited 2024 Apr 30];33(1):183–96. (2023). https://pubmed.ncbi.nlm.nih.gov/36375882/ Prophylactic underwater vessel coagulation for submucosal endoscopy Underwater coagulation using hybrid knife in peroral endoscopic myotomy for achalasia Tseng, C. W., Hsieh, Y. H., Lin, C. C., Koo, M. & Leung, F. W. Heat sink effect of underwater polypectomy in a porcine colon model. BMC Gastroenterol [Internet]. ;21(1):1–6. (2021). https://doi.org/10.1186/s12876-021-01985-1 Spadaccini, M. et al. Underwater EMR for colorectal lesions: a systematic review with meta-analysis (with video). Gastrointest Endosc [Internet]. 2019 Jun 1 [cited 2024 Apr 30];89(6):1109–1116.e4. https://pubmed.ncbi.nlm.nih.gov/30862352/ Despott, E. J. et al. Saline immersion therapeutic endoscopy facilitated pocket-creation method for endoscopic submucosal dissection (with video). Gastrointest Endosc [Internet]. 2019 Mar 1 [cited 2024 Apr 30];89(3):652–3. https://pubmed.ncbi.nlm.nih.gov/30784510/ Download references The publication fee was partially supported by “Ricerca Corrente” funding from Italian Ministry of Health to IRCCS Humanitas Research Hospital Materials and Chemical Engineering “Giulio Natta” Department of Gastroenterology and Digestive Endoscopy Showa University Northern Yokohama Hospital All authors participated in the data collection All the Authors revised and approved the final manuscript AC is a consultant for ERBERM is a consultant for ERBE 3DMatrix and Boston ScientificCH is a consultant for Alpha-Sigma Olympus and PentaxAR is a consultant for Medtronic Fujifilm and Olympus Others authors nothing to declares Below is the link to the electronic supplementary material Download citation DOI: https://doi.org/10.1038/s41598-024-83503-3 Aimed at informing and supporting coordinated management and conservation actions to benefit those ecosystems the program is an innovative effort that has the power to shape the future of saline lakes and help to secure a stable future for the birds that depend on them The Importance of Saline Lakes Throughout the U.S saline lakes are terminal systems where water flows in but only exits through evaporation leaving behind high concentrations of minerals and salts This unique process creates rich saline or alkaline habitats that support thriving populations of specialized macroinvertebrates (such as brine shrimp and brine flies) providing essential food for millions of migratory birds traveling along the Pacific Flyway These lakes and their associated wetlands—including ecosystems such as Great Salt Lake and Lake Abert—form an interconnected network of critical habitat for shorebirds and waterbirds serving as vital stopover sites during their migratory journeys as well as important breeding grounds Saline lakes also hold significant value for people. They drive economies, with industries like mineral extraction and brine shrimp harvesting generating significant revenue—more than $2 billion annually in the case of Great Salt Lake, which also supports about 7,700 jobs, according to a 2025 report from the Great Salt Lake Strike Team offering recreational opportunities and a deep sense of pride for surrounding communities Their striking beauty and ecological importance have inspired cultural traditions and foster a connection to a natural landscape that is unique to the arid West and Utah as the focus of this comprehensive research effort National Audubon Society's Saline Lakes Program played a key role in advocating for this critical legislation emphasizing the importance of science-based conservation strategies to protect these vital habitats both individually and as an interconnected network By securing federal support for comprehensive research Audubon and its partners helped lay the groundwork for a program that integrates hydrology and remote sensing to guide long-term management and conservation efforts. the Saline Lakes IWAA Program has already produced essential research that goes beyond data collection - it is beginning to develop analyses to provide the scientific foundation needed to make informed decisions about water management The USGS Saline Lake Ecosystem IWAA Program What makes the USGS IWAA program particularly powerful is its approach to integrating multiple components rather than studying individual components in isolation The program examines saline lake ecosystems through five interconnected scientific pillars: This integrated design emerged from an extensive review of the scientific literature and coordination among more than 120 stakeholders with expertise on saline lake systems including representatives from conservation organizations To ensure that research addresses the most relevant conservation needs the program aims to provide comprehensive data on water availability and lake health develop strategies to monitor and assess critical ecosystems and identify knowledge gaps to guide future research and resource management including understanding groundwater interactions as well as the effects of water chemistry on bird food resources are essential for information water management decisions and predicting how ecosystems may respond to future climate and water availability challenges In the two years since its establishment, the Saline Lakes IWAA program has already yielded crucial insights. For example, researchers have tracked 100 American Avocets across Lake Abert and Summer Lake in Oregon resulting in nearly one million location points that reveal how birds use these landscapes This data shows that individual avocets may visit up to 10 different lakes during their migratory journeys reinforcing the importance of focusing protection on the entire network of saline lake habitats Additional tracking efforts for species such as Wilson’s Phalarope and Black-necked Stilt are planned for upcoming field seasons expanding research across waterbird guilds to build a robust dataset that captures diverse movement patterns Insights such as these will enable managers and conservationists to develop targeted strategies that protect critical habitats across the network ensuring that birds have access to the resources they need throughout their migratory journeys Water quality monitoring has been equally revealing USGS scientists have documented dramatic salinity gradients across these terminal ecosystems ranging from near-freshwater conditions to conditions four times saltier than the ocean These variations shape the composition of invertebrate communities create diverse habitats that support different bird species Because the water chemistry of these systems determines the availability of food and suitable conditions for wildlife even small changes can disrupt the delicate balance that sustains these ecosystems. The program’s interdisciplinary approach is already providing needed data on water availability The findings and advancements highlight the important role that science plays in informing conservation decisions By integrating cutting-edge tracking technologies and those interested in the preservation of these habitats for birds and people with the information needed to safeguard these fragile ecosystems The Saline Lakes IWAA program demonstrates that when we invest in understanding these complex systems we can develop more effective strategies for their protection As climate change and increasing water demands continue to strain water resources the insights from the Saline Lakes IWAA program are more critical than ever The path forward requires collaboration across a wide range of partners making a concerted effort that will prove most successful if we: Expand monitoring networks to fill data gaps ensuring that we have a comprehensive understanding of the changing environment fostering a coordinated approach to conservation Support policies that prioritize sustainable water use and habitat protection Use technical insights to inform water resource management and conservation strategies Pursue a balanced approach that considers ecological ensuring that conservation measures are both effective and equitable Understanding how various ecological factors influence overall habitat condition is essential for effective conservation organizations like Audubon can pinpoint effective management strategies where conservation efforts should be focused and how we can balance the needs of both wildlife and people. Get action alerts about water issues in the West as well as issues that are affecting birds nationwide Hurricane season continues to strain the national supply of intravenous fluids to hospitals and dialysis centers around the country Flooding from Hurricane Helene in late September shut down one of the largest suppliers of IV fluids in the U.S sterile water for injection and other fluids that are crucial to the health care system the company and government officials are trying to make sure existing shortages aren’t worsened by the natural disasters the Food and Drug Administration announced it has authorized 19 IV products for temporary importation from Canada Baxter is limiting how much of its IV fluids customers like hospitals can buy to prevent hoarding and to try to ensure equitable access to the supply that is available It’s also trying to increase manufacturing at its other facilities to bridge the gap “We will spare no resource — human or financial — to restart operations and help ensure patients and providers have the products they need,” Baxter CEO José Almeida said in a company update. Baxter hopes to reopen the North Carolina facility in phases and get back to allowing customers to order close to normal amounts of certain products by the end of the year a second facility making the crucial medical products had to close its doors this week because of Hurricane Milton Braun factory making IV fluids in Daytona Beach Florida was not seriously impacted in the storm company spokesperson Allison Longenhagen told NPR in an email “We understand from discussions with employees that there have been no reported injuries but many are still without power,” she wrote in an email to NPR “We are especially thankful to the employees who remained at the site to provide updates throughout the storm.” Braun’s plan to ramp up production of IV fluids after the North Carolina Baxter shutdown threatened the national IV fluid supply Braun worked with the federal government to move 60 truckloads of finished IV solutions to a safe facility outside of Hurricane Milton’s path The FDA hasn’t declared any new IV fluid shortages yet, but six products were already in short supply One type of saline solution had been on the agency’s shortage list since 2018 Become an NPR sponsor NPS Starts Project to Stabilize Historic Salt Tram Towers Contact: Death Valley NP News Contact: Abby Wines Download the NPS app to navigate the parks on the go Metrics details Cyanobacteria are key elements of saline soils particularly in the formation of vast surface crusts in arid regions and mine spoil wastes These microorganisms are also abundant in areas that subjected to periodic wetting and submergence sheaths or mucilage and its component polysaccharides have important effects in improving soil structure in saline environments we studied a nitrogen-fixing cyanobacterium obtained from saline soils in Golestan Province combing both morphological and molecular techniques Phylogenetic analysis was performed via the complete sequence of the 16S rRNA gene along with 16S-23S internal transcribed spacer (ITS) secondary structures Further determinants were investigate using the sequences of the nifD The isolates were assigned to the genus Komarekiella on the basis of 16S rRNA phylogenetic analysis with 98.80 to 100% similarity to other species of this genus The 16S-23S ITS fold structures of the D1-D1’ and V2 helical regions distinguished the isolates from known Komarekiella species ITS p-distances between the studied strain and related taxa revealed that the Komarekiella sp isolate 1400 shared an ITS sequence similarity of 98.20 to 98.47% with the Komarekiella atlantica species These results increase our knowledge of the biodiversity and characterisation of the heterocystous genus Komarekiella in the saline soils of Iran isolated for the first time from this type of environment some morphological characteristics can vary significantly under different environmental conditions make species identification difficult when based on physical characteristics alone Studies concerning the diversity of heterocyst-forming cyanobacteria from saline soils in Iran are scarce which may make their use as biofertilisers difficult A Komarekiella isolate obtained from Iranian saline soils was molecularly and morphologically characterized so that our findings can help to increased knowledge of the biodiversity of nostocacean cyanobacteria biodiversity in saline soils with the expectation that future studies can develop inoculants to improve saline soil structure In October 2020, cyanobacterial biomass was collected from a saline soil area at coordinates of 36°51ʼ25ʼʼN and 54°26ʼ55ʼʼE in Gorgan city, Golestan province, Iran. Soil samples were obtained from the upper 5 cm layer and transported to the laboratory for cyanobacterial extraction and analysis. The information about the soil characteristics is listened in (Table 1) Small fragments of the cyanobacterial mat were cultured in liquid BG-11021 The biomass was periodically examined under a microscope to isolate a single colony The isolated colony was first labelled1355 and stored in an Erlenmeyer flask (250 mL) containing liquid BG-110 It was incubated at 28 ± 2 ºC exposed to light at approximately 50–55 µmol photons m⁻2 s⁻1 and maintained on a 14 h L/10 h D cycle Morphological analysis was performed using an Olympus CX31RTS5 stereoscope and an Olympus BX43 microscope (Olympus both of which were equipped with digital cameras In the morphological description we focused on morphological characters such as: thallus presence and type of akinete and heterocyst The obtained fresh cultures and exsiccates will be deposited in the cyanobacteria culture collection (CCC) and the ALBORZ Herbarium at the Science and Research Branch Sequences were aligned using BioEdit and compared to those in the NCBI databases via BLASTn and BLASTX with coding regions annotated using the NCBI ORF Finder and ExPASY proteomics servers psbA and rbcL were recorded in the DNA Data Bank of Japan (DDBJ) under the accession numbers OR669676 Gloeobacter violaceus was adopted as an outgroup in all phylogenetic Macroscopic growth with dark brown color of Komarekiella sp. isolate 1400 on solid media (a). Different light microphotographs (b-i) of Komarekiella sp. isolate 1400. Details are indicated with lowercase letters (b-i) according to the text. Microphotographs of the close related species to genus Komarekiella: Anabaena sp Cell color changed from pale green to dark brown as growth progressed Phylogenetic relationships among Komarekiella sp. isolate 1400 (in red) and related cyanobacteria based on 16S rDNA sequences (2028 bp) with Gloeobacter violaceus VP3-01 as outgroup. Numbers near nodes indicate standard bootstrap support (%)/ultrafast bootstrap support (%) for ML analyses. The scale bar indicates 0.05 substitutions per nucleotides. Phylogenetic analyses displaying the relationship among the nifD gene sequences (247 bp). Numbers near nodes indicate standard bootstrap support (%)/ultrafast bootstrap support (%) for ML analyses. The scale indicates 0.03 mutations per amino acid position. Phylogenetic analyses displaying the relationship among the psbA gene sequences (445 bp). Numbers near nodes indicate standard bootstrap support (%)/ultrafast bootstrap support (%) for ML analyses. The scale indicates 0.03 mutations per amino acid position. Phylogenetic analyses displaying the relationship among the rbcL gene sequences (728 bp) Numbers near nodes indicate standard bootstrap support (%)/ultrafast bootstrap support (%) for ML analyses The scale indicates 0.02 mutations per amino acid position Phylogenetic trees were used to compare the ITS p-distances of our strain with related Komarekiella strains isolate 1400 shared high ITS sequence similarity with these strains ranging from 98.20% with MTQ17-MM2 and MTQ8-MM1A to 98.47% with HA4396-MV6 clones C10B and C10A Secondary structures of the D1–D1´ helixes from 16S–23S intergenic spacers. Komarekiella sp. isolate 1400, Komarekiella atlantica CCIBT 3483, Komarekiella atlantica CCIBT 3481, Komarekiella atlantica CCIBT 3487, Komarekiella atlantica CCIBT 3552, Komarekiella atlantica CCIBT 3486, Komarekiella sp. SJR-PJCV1, Komarekiella atlantica HA4396-MV6, Komarekiella atlantica HA4396-MV6, Komarekiella atlantica MTQ17-MM2 and Komarekiella atlantica MTQ8-MM1A. Secondary structure comparisons of V2 from 16S–23S intergenic spacers. Komarekiella sp. isolate 1400, Komarekiella atlantica CCIBT 3483, Komarekiella atlantica CCIBT 3481, Komarekiella atlantica CCIBT 3487, Komarekiella atlantica CCIBT 3552, Komarekiella atlantica CCIBT 3486, Komarekiella sp. SJR-PJCV1, Komarekiella atlantica HA4396-MV6, Komarekiella atlantica HA4396-MV6, Komarekiella atlantica MTQ17-MM2 and Komarekiella atlantica MTQ8-MM1A. Secondary structure comparisons of the Box B helices from 16S–23S intergenic spacers. Komarekiella sp. isolate 1400, Komarekiella atlantica CCIBT 3483, Komarekiella atlantica CCIBT 3481, Komarekiella atlantica CCIBT 3487, Komarekiella atlantica CCIBT 3552, Komarekiella atlantica CCIBT 3486, Komarekiella sp. SJR-PJCV1, Komarekiella atlantica HA4396-MV6, Komarekiella atlantica HA4396-MV6, Komarekiella atlantica MTQ17-MM2 and Komarekiella atlantica MTQ8-MM1A. Secondary structure comparisons of V3 from 16S–23S intergenic spacers Komarekiella atlantica MTQ17-MM2 and Komarekiella atlantica MTQ8-MM1A Interestingly, the V2 region was found to be the same for all reference strains, except for Komarekiella sp. isolate 1400, which showed a different number of bilateral bulge (B) regions (Fig. 8) (Table 6) These differences between the studied regions suggested that our studied strain could be a potential new species for the genus Komarekiella however they are usually not sensitive enough markers to distinguish a species from each other The more in-deep studies of the strains including whole gene sequencing and more strain collections it seems to be needed these regions are not sensitive enough to separate taxa at the species level with the calculated 16S rRNA p-distance between the studied strains and related species within the genus Desmonostoc ranging from 98.21 to 98.48% These results broaden the understanding of the genetic variation and ecological range of the genus Komarekiella through a polyphasic analysis of Komarekiella sp demonstrating its presence in an atypical microhabitat within a saline soil region The identification of our strain will broaden the understanding of the geographical distribution of the genus Komarekiella as well as adding the new habitats where it could be isolated For other raw data contact the corresponding authors Action mechanisms of plant growth promoting cyanobacteria in crops in situ: a systematic review of literature and highly repetitive sequences commonly used in the phylogeny and species concept of the phylum cyanobacteria Phylogenetic placement of Dapisostemon gen two tropical heterocytous genera (Cyanobacteria) Morphological and molecular characterization of selected desert soil cyanobacteria: three species new to science including Mojavia pulchra gen Heterocyte-forming cyanobacteria from Brazilian saline-alkaline lakes Phylogenetically distant clade of Nostoc-like taxa with the description of Aliinostoc gen a phylogenetically distinct genus of Cyanobacteria along with the description of two new species and reclassification of Nostoc thermotolerans to Desikacharya thermotolerans comb Cyanobacteria) from Danxia mountain in China based on polyphasic approach Description of the cyanobacterial genus Desmonostoc gen as a distinct phylogenetically coherent taxon related to the genus Nostoc Extending the ecological distribution of Desmonostoc genus: proposal of Desmonostoc salinum sp a novel Cyanobacteria from a saline–alkaline lake Opening the gap: Rare lichens with rare cyanobionts–Unexpected cyanobiont diversity in cyanobacterial lichens of the order Lichinales Unravelling unknown cyanobacteria diversity linked with HCN production A new species of cryptic cyanobacteria isolated from the epidermis of a bottlenose dolphin and as a bioaerosol Multiple phylogenies reveal a true taxonomic position of Dulcicalothrix alborzica sp Molecular phylogenetic and morphometric evaluation of Calothrix sp A new strain of Neowestiellopsis (Hapalosiphonaceae): first observation of toxic soil cyanobacteria from agricultural fields in Iran Characterization of Neowestiellopsis persica A1387 (Hapalosiphonaceae) based on the cpc A Phylogenetic study of Aliinostoc species (Cyanobacteria) using pc-igs nifH and mcy as markers for investigation of horizontal gene transfer A new species of Scytonema isolated from Bilaspur strain histories and properties of pure cultures of cyanobacteria Taxonomic classification of cyanoprokaryotes (cyanobacterial genera) 2014 BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT IQ-TREE: a fast and effective stochastic algorithm for estimating maximum-likelihood phylogenies MrBayes 3.2: efficient Bayesian phylogenetic inference and model choice across a large model space Utility of 16S–23S ITS sequence and secondary structure for recognition of intrageneric and intergeneric limits within cyanobacterial taxa: Leptolyngbya corticola sp Mfold web server for nucleic acid folding and hybridization prediction Cyanobacteria): a new subaerial taxon from the Atlantic Rainforest and Kauai Hawaii nostocalean cyanobacteria isolated from phyllospheres biochemical and molecular characterization of Anabaena Aphanizomenon and Nostoc strains (Cyanobacteria Nostocales) isolated from Portuguese freshwater habitats Morphological and molecular characterization of Goleter sp (Nostocales Nostocaceae) isolated from freshwater in Iran The phylogenetic reconstruction of biosynthesizing genes from Cyanobacteria isolated from Ziarat waterfall of Golestan province Molecular phylogeny of two Aliinostoc isolates from a paddy field Nowruzi, B. & Afshari, G. 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Bioreclamatory studies on salt affected soil by using cyanobacterial biofertilizers. Plant Arch. https://doi.org/10.51470/PLANTARCHIVES.2021.v21.no2.065 (2021) Download references Faculty of Advanced Sciences and Technology Faculty of Converging Sciences and Technologies Download citation DOI: https://doi.org/10.1038/s41598-025-93257-1 Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology Help keep local news alive—donate to support our community reporting!Donate Lonnie Huhman Saline Area Schools, Saline Education Association Typically taking place behind closed doors the state of the negotiations between the teachers and school district was brought out before the community during the February 25 Saline Area Schools Board of Education meeting During the meeting’s Extended Public Comment Saline Education Association (SEA) president Bridget Corie spoke to the school board and gathered public We bring the facilities and curriculum to life And my team deserves more than just recognition—we deserve to be compensated fairly for the incredible work we do We deserve a contract that ensures a comfortable life so we can maintain our focus on the classroom we must keep Saline a district that attracts and retains the best talent – our community deserves it and we have an opportunity to lead – to show educators that working with our youth is valued and appreciated Make people the priority—because at the end of the day they are the driving force behind it all.” Here is Corie’s entire statement before the school board: Raising my children in Saline has been a source of pride for my family We value the district’s history of academic excellence and appreciate the many opportunities and services it provides There is so much to love about this community and school district When I ask my children what they love most about school their answers are never about the facilities They love school because of the people — the ones that stand before them These individuals give of themselves with care and compassion that cannot be measured And it is these incredible people who bring me here tonight I have the honor of representing the dedicated educators behind me as the President of the Saline Education Association and the challenges of this profession have only grown these heroes continue to show up every day because they care—because they believe every child deserves the opportunity to succeed They are the ones who recognize a spark of potential in a student and ignite their curiosity opening doors to new possibilities simply because they believe in them While they are deeply passionate about their work They deserve to be fairly compensated for the work they do The collective bargaining agreement between Saline Area Schools and the Saline Education Association expired on December 31 was shaped by the uncertainty surrounding COVID any pay increases were modest; with 0% on the scale for most staff for the past two years The district worked with us during the difficult years that followed the crash of the housing market so we were willing to work with them and prioritize the financial stability of the district Over the course of the three year contract record funding flowed into public education—even beyond ESSER relief funds the district’s fund balance has risen to approximately 24% the UAAL (pension liability) was permanently reduced by 5.75% we trusted that when it was time to negotiate our contract the district would respond appropriately We had a history of working together and a relationship with the district built on honesty and trust Today we are bargaining with a different administration and in a different financial climate Although we are making good progress through language items in the contract we are struggling to find common ground around the salaries of the people who work closely with children We have seen substantial increases in revenue and a very healthy fund balance We have also seen record inflation and increased healthcare costs have put a strain on our educators financially We believed the district would recognize this their first financial offer added 0% to the salary schedule While there has been some movement from the district they presented their final best offer with an unwillingness to recognize the permanent 5.75% UAAL reduction we would be able to factor in this new source of revenue The Saline Education Association has requested mediation from the Michigan Employment Relations Commission (MERC) Our most senior member of the bargaining team who has been bargaining the certified staff contract for over two decades will be going to mediation for the first time – as you can see I wanted to keep the fight behind closed doors After the district presented their final best offer I was told he had nothing to discuss with me and he stood in support of his team and hopefully all of you respect my decision to stand in support of my team the Sun Times News reached out to Saline Area Schools Superintendent Stephen Laatsch and the Saline Education Association negotiating team have held over 25 meetings where both parties have worked collaboratively to resolve many articles of the SEA contract and have agreed to mediation beginning March 10 We look forward to continuing to work with the SEA to reach a successful agreement.” Photo: Saline Education Association (SEA) president and teacher Bridget Corie speaking at the Feb Photo courtesy of Saline Area Schools Youtube channel Mike Williamson The Sun Times News is the hub of the most useful information in Chelsea Subscribe to our free daily newsletter to stay on top of all the local news National Machining League, Saline Area Schools, Saline High School was crowned the first-ever National Machining League Champion Badenhop earned both the prestigious title and a $10,000 grand prize the Sun Times News connected with Jackelyn Martin Saline Area Schools’ Executive Director of Communications and Community Relations The National Competition is part of the National Machining League which is a high-school level individual competition testing CNC/Machining skills up to 3-axis surfacing Project MFG Competitions are based on the design and testing of a “product” through a competition platform in which individual students compete against one another to complete a trade project Martin said schools can submit up to three students to individually compete and challenge each student’s ability to think critically and demonstrate skill and competency in machining which was held at Southwestern Illinois College on March 31-April 2 saw 15 qualifying students participating in the event The significance of this win was summed up well by Trent Trout a Computer Integrated Manufacturing Instructor in Saline and South and West Washtenaw Consortium Director Kara Stemmer “I am beyond proud of Semmy for not just making it to the National Championship The National Machining League is one of the most rigorous competitions I have seen he worked tirelessly to practice for the competition and to refine his skills as a machinist This is a big win for him and for the program.” “I strongly believe that the skills Semmy developed in Mr Trout’s Computer Integrated Manufacturing (CIM) class and Mr Vasiloff’s Computer-Aided Design (CAD) class — combined with the experience of competing industry-recognized competition — will give him a significant advantage as he moves forward Career and Technical Education classes truly have the power to change the trajectory of students’ lives We’re incredibly grateful to the industry partners who invest in our high school students; these experiences and relationships are invaluable.” “We all walked in with a large level of unknowns because you come from your home school where you maybe have one or two mini-mills and then you come to Southwestern Illinois College where they’ve got a $20 million brand-new shop it was still such a fun competition—and win you still get to come and gain this new experience.” Using hypertonic saline nasal drops can reduce the length of the common cold in children by two days according to a study that will be presented at the European Respiratory Society (ERS) Congress in Vienna They can also reduce the onward transmission of colds to family members The results of the ELVIS-Kids randomized controlled trial were presented by Professor Steve Cunningham from Child Life and Health Children have up to 10 to 12 upper respiratory tract infections which have a big impact on them and their families but no treatments that can make a cold get better quicker." ELVIS-Kids Chief Investigator Dr Sandeep Ramalingam had noted that salt-water solutions are often used by people in South Asia to treat a cold and wanted to explore if this clinical benefit could be replicated in a large study The research team recruited 407 children aged up to six years to a study where they were given either hypertonic saline ~2.6% (salt-water) nasal drops or usual care when they developed a cold 301 children developed a cold; for 150 of these their parents were given sea salt and taught to make and apply salt-water nose drops to the children's noses (three drops per nostril until well) and 151 children had usual cold care Professor Cunningham explains: "We found that children using salt-water nose drops had cold symptoms for an average of six days whereas those with usual care had symptoms for eight days The children receiving salt water nose drops also needed fewer medicines during their illness "Salt is made up of sodium and chloride Chloride is used by the cells lining the nose and windpipes to produce hypochlorous acid within cells which they use to defend against virus infection By giving extra chloride to the lining cells helps the cells produce more hypochlorous acid reducing the length of the virus infection and therefore the duration of symptoms." fewer households reported family members catching a cold (46% vs 61% for usual care) Eighty-two percent of parents said the nose drops helped the child get better quickly and 81% said they would use nose drops in the future Professor Cunningham added: "Reducing the duration of colds in children means that fewer people in their house also get cold with clear implications for how quickly a household feels better and can return to their usual activities like school and work "Our study also showed that parents can safely make and administer nose drops to their children and therefore have some control over the common cold affecting their children." Professor Alexander Möeller is Head of the ERS Paediatric Assembly and Head of the Department for Respiratory Medicine at the University Children's Hospital Zurich He said: "This is an important study that is the first of its kind to investigate the impact of salty nose drops in children with colds Although most colds usually don't turn into anything serious especially for young children and their families. "This extremely cheap and simple intervention has the potential to be applied globally; providing parents with a safe and effective way to limit the impact of colds on their children and family would represent a significant reduction in health and economic burden of this most common condition." The team hopes to further investigate the effect of saltwater nose drops on wheezing during colds after initial results from this study showed that children who received the drops had significantly fewer episodes of wheezing (5% vs 19%) European Respiratory Society Posted in: Child Health News | Medical Research News | Healthcare News Cancel reply to comment Learn how experts are advancing benzodiazepine analysis and detection using insights from the lab discusses how he is addressing today’s medical challenges using the technology of the future Explore how the Radian ASAP mass spectrometer is being used to streamline and enhance seized drug screening you can trust me to find commercial scientific answers from News-Medical.net please log into your AZoProfile account first Registered members can chat with Azthena, request quotations, download pdf's, brochures and subscribe to our related newsletter content A few things you need to know before we start Read the full Saline nasal drops or sprays may help reduce cold symptoms and lower the risk of spreading the virus to others You can purchase these products or make a saline solution at home using distilled or boiled water saline drops can sometimes cause mild irritation or dryness Consult your healthcare provider if symptoms persist or worsen Centers for Disease Control and Prevention. Manage common cold Centers for Disease Control and Prevention. About common cold Ramalingam S, Graham C, Dove J, Morrice L, Sheikh A. A pilot, open labelled, randomised controlled trial of hypertonic saline nasal irrigation and gargling for the common cold National Cancer Institute. Hypertonic saline Cunningham S, Evans E, Graham C, et al. A randomised controlled trial of hypertonic saline nose drops as a treatment in children with the common cold (ELVIS-Kids trial) American Lung Association. Facts about the common cold American Academy of Allergy, Asthma, and Immunology. Saline sinus rinse recipe UCLA Health. Risks and rewards of nasal rinses: what you need to know You are using an outdated browser. Please upgrade your browser to improve your experience and security Louisiana Department of Wildlife and Fisheries (LDWF) Inland Fisheries biologists deployed 100 Christmas trees at two new locations within the Saline-Larto Complex to enhance fish habitat these artificial reefs provide vital protective cover for young fish while also attracting adult bass and crappie The Christmas trees used for this project were generously donated by Lowe’s Home Improvement stores in Pineville and Alexandria but anglers can use the coordinates below to locate the new structures along with other reefs throughout the complex The new reef locations will be added to LDWF’s Louisiana Outdoor Explorer in the near future. To view the location of other public freshwater artificial reefs throughout the state, visit the Louisiana Outdoor Explorer click on the “Get on the Water” tab then select “Freshwater Artificial Reefs” under the layer list For questions regarding the Saline-Larto Lake Complex, please contact LDWF Inland Fisheries Biologist Manager Shelby Richard at (318) 487-5352 or srichard@wlf.la.gov Metrics details To evaluate the hemodynamic effects and the safety profile of fluid bolus resuscitation with hypertonic saline albumin (HSA) in critically ill children we performed a prospective observational pilot study between October 2018 and May 2021 in the pediatric intensive care unit (PICU) in a tertiary hospital in Madrid Sixty-four HSA boluses were analyzed in 23 patients A mean volume of 5.7 ml/kg (Standard Deviation 56% of them had undergone cardiac surgery in the previous 72 h and 47.8% associated right ventricular dysfunction and diastolic blood pressure and a decrease in the vasoactive index was observed after the infusion of HSA This effect lasted for twenty-four hours (p < 0.05) the amount of fluid requirements decreased significantly in the 6 h following HSA infusion [8.7 ml/kg (SD 9.6) vs 15.1 ml/kg (SD 13.6) in the previous 6 h (p < 0.05)] Serum levels of sodium and chloride increased after the infusion reaching their peak concentration after one hour (143 mEq/L (SD 3.5) and 109.7 mEq/L (SD 6) respectively) HSA-related metabolic acidosis or acute kidney injury were not observed in this study Hypertonic saline albumin is safe and effective when infused at a dose of 5 ml/kg in critically ill children further research is required to confirm our findings Fluid bolus therapy (FBT) is a first line therapy for resuscitation of different types of shock and has been a recommendation of international guidelines for about two decades fluid resuscitation remains controversial in pediatric patients and infusion rate is still a major therapeutic challenge Many types of fluids have been used as FBT: isotonic crystalloids natural (albumin) and synthetic colloids (gelatin as well as different combinations of colloids and hypertonic crystalloids none of them has proven to be the ideal resuscitation fluid long-lasting blood volume expansion with few side effects This is why even more restrictive strategies are being explored Severe hyperchloremic acidosis was not observed The main objective of this study was to evaluate the short-term hemodynamic effects and the safety profile of HSA fluid bolus resuscitation in critically ill children pilot study was conducted in the 17-bed medical-surgical pediatric intensive care unit (PICU) of a tertiary hospital in Madrid It is a national referral center for congenital and acquired heart disease and it counts with an advanced cardiac surgery program that includes heart transplant extracorporeal membrane oxygenation (ECMO) and ventricular assist device (VAD) programs All patients between 0 and 16 years of age who received HSA boluses during PICU admission between October 2018-May 2021 were included regardless of their diagnosis on admission Informed consent was obtained from all subjects and/or their legal guardian(s) A local protocol regarding HSA bolus therapy was designed before the study started (Supplementary material-1) HSA was indicated in patients with suspected hypovolemia and persistent hypotension after conventional FBT with more than 20 ml/kg of colloid or crystalloid solutions especially in patients that had right ventricular dysfunction or a positive net fluid balance and intravascular hypovolemia despite fluid overload in the cellular and extravascular spaces HSA fluid bolus therapy was decided at the discretion of the prescribing physician HSA was contraindicated in patients with serum sodium ≥ 150 mEq/L and blood products at the discretion of the treating clinicians and other aspects of patient care were performed at the discretion of the treating clinicians The resulting fluid is equivalent to a mixture of 5% albumin and 3% hypertonic saline An osmolarity analysis of the HSA solution was performed using the OsmoSpecial 1 osmometer (Astori Tecnica SR obtaining a median fluid osmolarity of 980 mOsm/L (Standard Deviation HSA boluses were infused by a central intravenous access at a dose of 5 ml/kg over a 15-minute period repeated 5 ml/kg boluses were administered especially if hypovolemia was suspected (active bleeding excessive fluid output such as high diuresis increased output trough surgical drains….) and if a positive response was observed previously and analytical variables were recorded before and 1 Patients were followed until discharge from the PICU or death Seriated blood tests that included liver and renal function blood gas profiles and coagulation were performed daily during the first 48 h after infusion HSA safety profile evaluation included potential adverse effects such as metabolic acidosis Pediatric Risk of Mortality Score III (PRISM-III) was calculated for each patient on admission or Blood pressure (BP) was monitored invasively in all patients Since BP reference values vary widely in the pediatric population the variable “variation in BP” was calculated using the following formula: (initial BP – final BP) / 100 This was used for all BP measurements (systolic and diastolic BP at each time point of the study) Net fluid balance (total fluid input - total fluid output) was expressed in ml/kg at the end of the three following work shifts after each HSA bolus infusion The morning shift includes the period from 8 a.m transfusion requirements and use of renal-replacement therapy were recorded daily until discharge from the ICU or death IBM SPSS Statistics 25.0 system (IBM SPSS Statistics Quantitative variables were expressed as mean and standard deviation or median and interquartile range depending on whether the sample was normally distributed Qualitative variables were expressed as percentages The Chi-square and Fisher tests were used to compare categorical variables Student’s T and repeated measures ANOVA tests were used for continuous variables Sixty-four HSA fluid boluses were analyzed in 23 patients The most common reason for bolus administration was acute hypotension (62.5%) followed by suspected hypovolemia without hypotension (29.7%) A mean volume of 5.7 ml/kg (SD 2.3 ml/kg) was delivered per bolus Patients had received at least one fluid bolus in the 6 h prior to each HSA bolus in 92% of cases, with a mean prior volume infusion of 15.1 ml/kg (SD 13.6 ml/kg). The most frequent resuscitation fluid was balanced gelafundin solution, according to our local protocol. Table 2 shows the difference between baseline parameters and those 1h representing more than half of the HSA boluses recorded (64%) received more than one HSA bolus over time (36.6% within the next 24 h and 22% between the next 24–48 h) The mean cumulative volume that was infused in patients who received repeated boluses was 22.2 ml/kg (SD 15.7) 23 boluses) received more fluids than those without CRRT (28.3 ml/kg (SD 15.0) vs A patient with septic shock who required mechanical ventilation and CRRT received up to 10 HSA boluses (64.6 ml/kg) over an 18-day period (with a maximum of 2 boluses every 24 h) General linear model of the variation (percentage increase) of systolic blood pressure (SBP) mean arterial pressure (MBP) and diastolic blood pressure (DBP) after the infusion of hypertonic saline albumin Statistically significant values are marked with an asterisk (*) Most patients (70.3%) required further fluid boluses within the next 6 h after the administration of HSA with a mean accumulated volume of 8.7 ml/kg (SD 9.6) Repeated boluses occurred a mean of 8.2 h later (SD 7.4 h) the amount of volume infused after the HSA bolus was significantly lower than before (15.1 ml/kg in 6 h A change in fluid balance was observed after HSA infusion Mean fluid balance during the shift in which HSA was administered was + 15.8 ml/kg (SD 24 ml/kg) and it decreased in the following shifts: -1 ml/kg (SD 25 ml/kg) in the shift immediately after HSA infusion and + 4.3 ml/kg (SD 24 ml/kg) in the shift after that (p < 0.05) Thirty-eight patients (58%) had signs of fluid overload prior to HSA infusion while 40 patients (61%) showed FO 24 h after the bolus (chi-square 0.60 The proportion of patients with pulmonary edema before and after the HSA bolus was 19% and 10% respectively (chi-square 1.91 Three patients (13%) required initiation of CRRT in the 24 h following HSA infusion All of them were in the first 24 h after cardiac surgery for transposition of the great arteries (two after a Nikaidoh procedure and one after a Rastelli procedure) and had right ventricular dysfunction and FO One of these patients had chronic renal failure prior to admission Two of these patients required two HSA boluses before CRRT each General linear model of the variation in sodium and chloride levels (mEq/L) after the administration of hypertonic saline albumin Blood pH, bicarbonate, and albumin were significantly higher (p < 0.05) and lactic acid levels were significantly lower (p < 0.05) twenty-four hours after HSA infusion. No differences were observed regarding blood creatinine or urea concentrations. Urine output remained stable after each bolus (Table 2) Renal disfunction was observed in five patients surrounding the HSA infusion: three patients required initiation of CRRT and the rest of them (2 patients) developed acute kidney injury (AKI) stage 1 according to the KDIGO stratification Fibrinogen slightly increased after HSA (p < 0.05), but no changes were observed in INR and aPTT, as shown in Table 2 30% of patients received red blood cell (RBC) transfusions 28% received platelets and 25% received plasma in the twenty-four hours following HSA bolus Side effects such as anaphylactic reactions or acute lung edema related to the infusion of HSA were not observed Mortality rate in our cohort was 13% (3 patients) due to multiorgan failure as a worsening in their clinical status None of the deaths could be directly attributed to the use of HSA This is the first study to evaluate hemodynamic effects and safety of fluid bolus resuscitation with hypertonic saline albumin in pediatric patients According to the results of this pilot study HSA seems to be an effective resuscitation fluid safe enough to continue performing a larger study Prospective clinical trials with larger sample sizes are needed to assess the effectiveness and safety of HSA and compare it to that of other fluids in pediatric patients In patients with severe ventricular dysfunction it has not been demonstrated that the exclusive use of vasoactive drugs is capable of completely spare the need for fluid boluses achieves the longest intravascular permanence and the shift of interstitial fluid to the intravascular space with the minimum side effects on the endothelium and coagulation The use of HSA administered at a dose of 5 ml/kg can meet several of the requirements of this ideal fluid Sodium and chloride blood levels mildly and transiently increased in our patients but returned to normal levels after a few hours Metabolic acidosis after HSA was not observed pH improved over the 24 h following the infusion The incidence of AKI in our unit is currently 25% according to our local registry (unpublished data) the incidence of AKI in this study is similar to that expected in this cohort HSA bolus safety is still inconclusive and needs further research to conclude the net effect of the potential benefits of using albumin and lower infusion volumes as opposed to the potential deleterious effects of hyperchloremia is unknown Given the fact that this is an observational pilot study it is difficult to determine whether HSA bolus therapy could influence the management of net fluid balance fluid balance switched from being largely positive in the shift prior to hypertonic albumin bolus to neutral in subsequent shifts This finding cannot be attributed solely to HSA infusion; however it seems to indicate that HSA bolus therapy does not pose a risk to the patients further studies are required regarding this topic which is high considering that our global annual mortality rate is between 2 and 3% this is a selected cohort with high severity scores and that required high vasoactive a higher need of fluid bolus administration it is a single-center pilot study with a small sample size it only evaluates the effect of HSA but does not allow comparisons between HSA and other fluids our patients were mainly children with a congenital heart disease many of them in the immediate postoperative period of cardiac surgery the results might not be extrapolated to other populations of critically ill patients Another major limitation is the presence of many confounding factors that affect hemodynamic status a preliminary study that requires further consideration for future research Hypertonic saline albumin seems to be an effective and safe resuscitation fluid in critically ill children It could have a special indication in hemodynamically unstable patients who do not tolerate high volumes of fluids and in those with fluid overload our results must be interpreted with caution as larger studies with different treatment groups longer observation times and confounding factor control are needed The datasets used and/or analysed during the current study are available from the corresponding author on reasonable request Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children Medication and fluid management of pediatric sepsis and septic shock Duration of hemodynamic effects of crystalloids in patients with circulatory shock after initial resuscitation Bundles of care for resuscitation from hemorrhagic shock and severe brain injury in trauma patients-translating knowledge into practice Balanced Versus Unbalanced Fluid in critically Ill children: Systematic review and Meta-analysis Impact of the magnitude and timing of Fluid overload on outcomes in critically Ill children: A report from the multicenter international assessment of worldwide acute kidney injury Mortality after fluid bolus in African children with severe infection Rubbing salt into wounds: Hypertonic saline to assist with volume removal in heart failure Hypertonic saline for fluid resuscitation in ICU patients post-cardiac surgery (HERACLES): A double-blind randomized controlled clinical trial Efficacy and safety of hypertonic saline solutions fluid resuscitation on hypovolemic shock: A systematic review and meta-analysis of randomized controlled trials Hyperoncotic colloids and acute kidney injury: A meta-analysis of randomized trials Colloid solutions for fluid resuscitation in patients with sepsis: Systematic review of randomized controlled trials Role of albumin in the preservation of endothelial glycocalyx integrity and the microcirculation: A review Association between Fluid Balance and outcomes in critically Ill children: A systematic review and meta-analysis Different concentrations of albumin versus crystalloid in patients with sepsis and septic shock: A meta-analysis of randomized clinical trials Early human albumin administration is associated with reduced mortality in septic shock patients with acute respiratory distress syndrome: A retrospective study from the MIMICIII database SAFE Study Investigators; Australian and New Zealand Intensive Care Society Clinical Trials Group; Australian Red Cross Blood Service; George Institute for International Health et al Saline or albumin for fluid resuscitation in patients with traumatic brain injury Fluid resuscitation in patients with traumatic brain injury: What is a SAFE approach Hypertonic saline albumin and terlipressin plus hypertonic saline albumin in an infant animal model of hypovolemic shock hypertonic saline and hypertonic saline colloid resuscitation fluids in an infant animal model of hypovolemic shock Recommendations for hemodynamic monitoring for critically ill children-expert consensus statement issued by the cardiovascular dynamics section of the European Society of Paediatric and neonatal intensive care (ESPNIC) Feasibility and utility of the venous excess ultrasound score to detect and grade central venous pressure elevation in critically Ill children Effects of saline or albumin fluid bolus in resuscitation: Evidence from re-analysis of the FEAST trial Hypertonic-hyperoncotic solutions improve cardiac function in children after open-heart surgery fluid demand regimen (HALFD) in resuscitation Right ventricular dysfunction before and after cardiac surgery: Prognostic implications Intensive care unit management of patients with severe pulmonary hypertension and right heart failure Contemporary management of acute right ventricular failure: A statement from the Heart Failure Association and the Working Group on Pulmonary Circulation and right ventricular function of the European Society of Cardiology Right heart failure: A narrative review for emergency clinicians Assessment of acute kidney injury in neurologically injured patients receiving hypertonic sodium chloride: Does chloride load matter Renal failure associated with unrecognized hyperoncotic states after pediatric heart surgery Epidemiology of acute kidney injury in critically ill children and young adults Postoperative neutrophil gelatinase-associated lipocalin predicts acute kidney injury after pediatric cardiac surgery Hyperchloremia and association with acute kidney injury in critically ill children Multiple electrolytes solution versus saline as bolus fluid for resuscitation in pediatric septic shock: A multicenter randomized clinical trial Hyperchloremia and hypernatremia in critically ill children Is the use of colloids for fluid replacement harmless in children and Blood Institute (NHLBI) recipient epidemiology and donor evaluation Study-IV-Pediatric (REDS-IV-P) Transfusion practices in pediatric cardiac surgery requiring cardiopulmonary bypass: A secondary analysis of a clinical database Download references We would like to thank the Gregorio Marañón Hospital Pharmacy Department for their valuable help conducting HSA osmolarity tests This work was developed within the framework of the research network Primary Care Interventions to Prevent Maternal and Child Chronic Diseases of Perinatal and Development Origin Network (RICORS) RD21/0012/0011 Hospital General Universitario Gregorio Marañón Gregorio Marañón Health Research Institute Primary Care Interventions to Prevent Maternal and Child Chronic Diseases of Perinatal and Development Origin Network (RICORS) RD21/0012/0011 Maternal and Child Public Health Department Sara de la Mata-Navazo (SMN): Formal Analysis Writing-Original Draft-Sarah Nicole Fernández (SF): Investigation Writing—Reviewing and Editing-María Slöcker-Barrio (MSB): Formal Analysis Investigation-Alicia Rodriguez-Martínez (ARM): Investigation-Laura Torres (LT): Investigation-Santiago Rodríguez-Tubio (SR): Investigation-Claudia Olaya (CO): Investigation-Cristina de Ángeles (CA): Investigation-Pablo González Navarro (PGN): Formal Analysis Data Curation-Jesús López-Herce (JLH): Conceptualization Funding acquisition-Javier Urbano (JU): Conceptualization This study was approved by local Ethics and Research Committee of the Gregorio Marañón University Hospital (number 23/2017) and the procedures were followed in accordance with the ethical standards of the responsible committee on human experimentation and with the Helsinki Declaration of 1975 Download citation DOI: https://doi.org/10.1038/s41598-024-73588-1 Hypertonic saline nose drops shortened cold symptom duration in young children and decreased household transmission according to findings presented at the European Respiratory Society International Congress in Vienna The ELVIS-Kids study was inspired by the use of saltwater solutions in South Asia to treat cold symptoms “Hypertonic saline can reduce symptom duration in children aged 0 to 6 years by 2 days (a 25% relative reduction) and can also reduce transmission of colds within households and reduce the need for families to buy pharmacy medicines as treatments,” Steve Cunningham professor of pediatric respiratory medicine in the department of Child Life and Health at The University of Edinburgh The randomized controlled trial included 301 children aged 0 to 6 years with upper respiratory tract infections The researchers assigned 150 children to receive hypertonic saline nose drops (2.6%) and 151 to receive typical cold care they taught parents how to make 2.6% saline with sea salt and water and instructed parents to administer three drops in each nostril four times per day Parents in both groups documented symptoms and side effects for 28 days following symptom onset The researchers also swabbed children’s noses for the first 5 days of symptoms to test for viruses Parents reported administering the saltwater drops a median of three times per day for a median of 5 days The children who received nose drops experienced a median of 6 days of symptoms (interquartile range [IQR] whereas the control group experienced a median of 8 days of symptoms (IQR Fewer household members developed cold symptoms in the nose drops group than the control group (41% vs Cunningham explained that the mechanism of action: “Salt is made up of sodium and chloride By giving extra chloride to the lining cells this helps the cells produce more hypochlorous acid and therefore the duration of symptoms.” The researchers reported mild and infrequent side effects of hypertonic saline during the study “There are no licensed premade hypertonic saline nose drops available for children,” Cunningham told Healio “There are premade saline nose drops available from pharmacies these are not the strength that was used in the trial and so may not be as effective We hope that a hypertonic saline nose drop product that could be used to treat children will be developed soon.” Abstract OA1985: A randomized controlled trial of hypertonic saline nose drops as a treatment in children with the common cold (ELVIS-Kids trial) Presented at: European Respiratory Society International Congress; Sept 7-11 Get the latest news and education delivered to your inbox The email address associated with your Healio account is: If you would like to edit or change the email address that your subscriptions and alerts are sent to You'll receive reminders to complete your saved activities from Healio CME Seattle Mariners starting pitcher Logan Evans talks with manager Dan Wilson after pitching during the fifth inning against the Miami Marlins of a baseball game .st1{fill-rule:evenodd;clip-rule:evenodd;fill:#2a2a2a}By Greg Wickliffe |gwickliffe@mlive.comIt didn’t take long for Logan Evans to settle in on the mound during his MLB debut on Sunday Evans was named to the Seattle Mariners’ 40-man roster and got the nod to start against the Miami Marlins on Sunday giving the rookie right-hander little time to get out any jitters After forcing two ground outs to start the game the former Saline baseball star gave up a home run in the first inning to Miami Marlins’ slugger Austin Ramirez Evans didn’t let the home run faze him as the 23-year-old quickly bounced back Evans forced a ground out to close the first inning and allowed only one hit and one run the rest of the way providing Evans a victory in his first career start He finished the game with three strikeouts two hits and two earned runs allowed in five innings of work Sunday’s start capped off a meteoric rise for Evans who was drafted by Seattle in the 12th round of the 2023 MLB Draft after playing collegiately at Penn State and Pittsburgh Evans has climbed from the rookie league to the Majors making stops at Single-A and Double-A before starting 2025 with the Triple-A Tacoma Rainiers Evans made five starts with the Rainiers this season going 1-1 with 23 strikeouts and a 3.05 ERA in 25.2 innings prior to his call up to the Majors Evans earned all-state honors as a pitcher and was a member of the Hornets’ 2017 state title team Use of and/or registration on any portion of this site 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All rights reserved (About Us) The material on this site may not be reproduced except with the prior written permission of Advance Local Community Rules apply to all content you upload or otherwise submit to this site YouTube's privacy policy is available here and YouTube's terms of service is available here Ad Choices NOVI — A hot goaltender can be the great equalizer in playoff hockey Saline was a heavy underdog against Brighton in a Division 1 regional semifinal Thursday night at Novi Ice Arena but the goaltending of junior Jack Derksen allowed the unranked Hornets to put a scare into the fifth-ranked Bulldogs The game was tied 1-1 midway through the third period before Brighton scored twice in the third to avert an upset bid with a 3-1 victory in its playoff opener The Bulldogs (14-10-2) outshot the Hornets (15-10-2) by a whopping 62-10 margin “Their goalie was good,” Brighton coach Kurt Kivisto said He saw a lot of stuff and smothered a lot of stuff We needed more traffic to make it more difficult for him.” Saline scored first just 56 seconds into the second period on a power-play goal by Chris Thornell Brighton’s Eddie Wheeler tied it less than two minutes later Everett Bosak scored the go-ahead goal with 7:50 left in the game Jacob Daavettila put the game away by scoring a power-play goal with 1:41 remaining The Bulldogs have played in the last three state Division 1 championship games but they graduated many of the key players from that team “We were probably a little bit tight going in and played like that,” Kivisto said It’s good to get that one behind us and hopefully learn from that and be better on Wednesday.” Brighton will face eighth-ranked Northville in the regional championship game at 7:45 p.m but the Mustangs have been bolstered by the addition of defenseman Isaac Nelson since that game Nelson had nine goals and eight assists in 14 regular-season games They have a pretty good defenseman they’ve added since then who has been part of their team We have a young team that’s grown a lot since that time Brighton beat Northville 7-1 in the regional championship game last season The Bulldogs have been peaking at the right time going 6-0-1 in their last seven games after an 8-10-1 start “We like how we’ve been playing down the stretch,” Kivisto said We have a good feeling every day at the rink It’s good to get the first playoff game under our belt.” The Brighton-Northville winner will play the Plymouth-Salem winner in the state quarterfinals at 1 p.m Vince Salmon scored 13 points and Tristian Provancher seven to lead Brighton in its regular-season finale The Bulldogs will face Monday’s Fenton-Hartland winner in the district semifinals Wednesday in Brighton Coen Chwalek 10 and Layne Broker eight for Hartland Williamston scored the last nine points of the game to pull away from a 43-43 tie Wyatt Soli had 16 points and Sam Shrader 11 for the Gladiators Audrey Wardlow scored 17 points and Riley Smith 10 for Pinckney (13-8) Audrey Johnson had 24 points for Livingston Christian New research from a randomized controlled trial presented at the European Respiratory Society (ERS) Congress in Vienna this week suggests that simple saline nasal drops can reduce the length of the common cold in children by 2 days The authors also said using saline nasal drops can reduce forward transmission often virus to household members. The trial included 407 children aged up to 6 years who were either given hypertonic saline (salt-water) nasal drops or usual care when they developed a cold parents were instructed to apply saline drops to the children's noses (three drops per nostril We found that children using salt-water nose drops had cold symptoms for an average of six days where those with usual care had symptoms for eight days "We found that children using salt-water nose drops had cold symptoms for an average of six days The children receiving salt water nose drops also needed fewer medicines during their illness," said study author Steve Cunningham fewer households reported family members catching a cold (46% vs 61% for usual care) when kids were given saline drops. Cunningham explained that the chloride in salt is used by the cells lining the upper respiratory tract to produce more hypochlorous acid "Reducing the duration of colds in children means that fewer people in their house also get a cold but there are more signs of decline in many areas the Centers for Disease Control and Prevention (CDC) said today in its latest updates Wastewater SARS-CoV-2 detections are still high but are dropping in all regions except for the Midwest according to the CDC's latest tracking. Test positivity showed another small decline and is at 16.4% nationally but is higher in the Midwest and Middle Atlantic Emergency department visits declined 10.2% from the previous week but are still at the moderate level in some of the southeastern states especially in seniors and children younger than 2 years old but are also showing downward trends. One metric that rose last week was deaths, which were up 18.2% compared to the previous week, with COVID making up 2.6% of US deaths. For the week ending August 31 COVID deaths averaged roughly 900 per week the CDC said it expects that the upcoming fall and winter virus season will have similar or lower peak numbers of hospitalization from COVID and respiratory syncytial virus (RSV) as last year. it noted that peak will likely be higher than the years before COVID emerged the group said in its update that covers the main three respiratory viruses "COVID-19 activity this fall and winter will be dependent on the progression of the ongoing summer COVID-19 wave." A study today of 1,296 pediatric Italian COVID-19 patients who underwent multiple follow-ups over 2 years shows decreasing rates of long COVID over time The study is published in eClinicalMedicine and is one of the longest studies conducted on kids with long COVID. The findings are based on outcomes seen at a single clinic in Rome from January 2020 through February 2024 and 24 months after a confirmed COVID-19 infection 8.6% (114) were asymptomatic and 88.6% (1,169) had mild Most children were diagnosed as having COVID-19 when the Omicron variant was prevalent (939 More than three fourths of children (79.6%) were not vaccinated before the infection Two factors were associated with increased risk of long COVID diagnosis through 18 months: age of 12 years or older (odds ratio [OR] 1.58 to 8.64) and being infected with the original strain of the virus (OR Older age and original and Alpha infection were associated with long COVID at 3 months as was female sex and comorbidities. Long-COVID diagnosis was considered after continuation or development of new symptoms 3 months after the initial SARS-CoV-2 infection. COVID-19 vaccines were associated with a lower risk of developing Long Covid particularly in adolescents "COVID-19 vaccines were associated with a lower risk of developing Long Covid particularly in adolescents while re-infections had a minimal burden on most patients although one case of Long Covid following re-infection was identified," the authors wrote. UK public health officials have determined that the likely source of a 2022 outbreak of Shiga toxin–producing Escherichia coli (STEC) O157:H7 was lettuce contaminated by sheep feces washed to the field by heavy rainfall and flooding related to climate change The investigation findings detail how consumption of the tainted lettuce sickened 259 people The UK Health Security Agency–led research team conducted whole-genome sequencing traced the lettuce back through the supply chain and used new methods to determine rainfall and temperature before the outbreak and the location of the sheep suspected to be the source of the feces "The gastrointestinal tract of ruminants is the ecological niche of STEC with cattle and sheep being the main animal reservoirs," the investigators wrote "Food items frequently associated with food-borne outbreaks of STEC O157 include raw or undercooked beef or lamb meat products and fresh produce exposed to rainwater run-off or irrigation water containing animal faeces." The 19 patients interviewed reported exposures such as restaurant dining and eating chicken A frequency-matched study involving 41 patients and 206 controls linked the illness to consumption of chicken or salad. Loyalty-card data and supply-chain investigations tied a single lettuce grower to all food service establishments or retailers of interest Our new techniques could help to predict and prevent future outbreaks and inform risk assessments and risk management for farmers growing fresh produce for people to eat The investigators identified no failures by the lettuce grower but a geospatial analysis independently identified the grower as the probable outbreak source and weather data suggested that floodwater carried STEC-contaminated sheep feces to the lettuce crops "Climate change will have increasing impacts on our health and food security," the authors wrote "Our new techniques could help to predict and prevent future outbreaks and inform risk assessments and risk management for farmers growing fresh produce for people to eat." Global Virus Network scientists highlight the need for robust surveillance and readiness for potential human-to-human viral transmission only the severe infections continued to cause symptoms. Almost 90% of the European cases were reported in Romania The Wall Street Journal reports the Trump administration is investing $500 million in the universal vaccine project There are currently 59 herds quarantined in 4 Idaho counties The CDC today addressed what's known about treatments pushed by Kennedy urging caution about vitamin A use and citing individual decision-making by heath providers for others Yet uptake of the vaccine was extremely low—less than 4% through November 2024 Today Novavax weighed in on the FDA's latest stipulations noting that postmarketing commitments aren't unusual and are in place for many approved drugs and biologics 44% of respondents said the new leaders will make them trust their health recommendations less than they used to and Ohio notes an infection in an unvaccinated adult CIDRAP - Center for Infectious Disease Research & PolicyResearch and Innovation Office Email us © 2025 Regents of the University of Minnesota All rights Reserved.The University of Minnesota is an equal opportunity educator and employer Research and Innovation Office | Contact U of M | Privacy Policy Newsletter subscribe Doug Marrin dam removal, environmental restoration, infrastructure costs, public engagement, Saline River Dam The City of Saline is grappling with a critical decision of whether to rehabilitate the aging Saline River Dam or remove it altogether and the community is engaged in discussions about the potential costs The city posted a list of frequently asked questions (FAQs) on its website built in the late 1800s and modified in the 1930s A 2020 safety inspection revealed significant structural issues that need addressing to keep the dam safe and operational This has prompted the City to evaluate long-term solutions the City presented a breakdown of costs for both options: funding assistance is more likely for dam removal potentially reducing local taxpayer burdens Will removal increase downstream flooding?No The Saline River Dam was not designed for flood control and contributes minimally to it Removal would not significantly impact downstream flooding Would removing the dam harm natural habitats?While Mill Pond is a man-made feature returning the river to a natural state could benefit the environment and free passage for fish and aquatic wildlife What would the area look like post-removal?Renderings from the December 9 presentation depict a naturalized river channel similar to Curtiss Park Additional green space could enhance Mill Pond Park with new public amenities designed with community input When will decisions be made?The final feasibility study will be presented in February or March 2025 Public comments are being collected until January 31 The City emphasizes the importance of public engagement Residents are invited to share their concerns and ideas which will be documented in the final report Opportunities for input will continue through public meetings and design phases should the City opt for removal The city is receiving public comment for inclusion in the feasibility report until January 31 There will be additional opportunities for public comment in the future Contacts are listed below for public input The entire FAQ can be found at https://www.cityofsaline.org/_T2_R70.php