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About Kobe

Ever tried it? Hands kneading, slow as *Melancholia*’s planet crash. “The Earth is evil,” Kirsten Dunst mumbles in that film, but this? This is good, mate. Little fact - in Japan, they’ve got this style, Nuru, uses seaweed gel. Slippery as a Balrog in a bath! Had me giggling imagining hobbits slipping around. Pro tip: dim lights, warm oil, no rush - sets the mood perfect. Surprised me how it’s less about the naughty bits, more about feeling alive.

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Then, outta nowhere, my buddy Hiro shows up. He’s got this wild look in his eyes. “You won’t believe what I just saw!” I’m like, “Dude, I’m in the middle of a machine apocalypse here!” But he insists. Turns out, there’s a street performer on Nakamura Street doin’ some crazy acrobatics. I mean, who doesn’t love a good street show?

Discovery of TP0628103: A Highly Potent and Selective MMP-7 Inhibitor with Reduced OATP-Mediated Clearance Designed by Shifting Isoelectric Points | Journal of Medicinal Chemistry